ZA200303341B - Salts of a isothiazole-4-carboxamide and their use as anti-hyperproliferation agents. - Google Patents

Salts of a isothiazole-4-carboxamide and their use as anti-hyperproliferation agents. Download PDF

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Publication number: ZA200303341B
Authority: ZA; South Africa
Prior art keywords: salt; isothiazole; ray powder; bromo; pyrrolidin
Prior art date: 2000-11-28

Application number

ZA200303341A

Other languages

English (en)

Inventor

Thomas G Gant

Williams Glenn Robert

Original Assignee

Pfeizer Products Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-11-28

Filing date

2003-04-30

Publication date

2004-04-30

2003-04-30 Application filed by Pfeizer Products Inc filed Critical Pfeizer Products Inc

2004-04-30 Publication of ZA200303341B publication Critical patent/ZA200303341B/en

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HXHAJRMTJXHJJZ-UHFFFAOYSA-N 3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-(4-pyrrolidin-1-ylbutylcarbamoylamino)-1,2-thiazole-4-carboxamide Chemical compound S1N=C(OCC=2C(=CC(Br)=CC=2F)F)C(C(=O)N)=C1NC(=O)NCCCCN1CCCC1 HXHAJRMTJXHJJZ-UHFFFAOYSA-N 0.000 claims description 24
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- C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
- C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
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Medicinal Chemistry (AREA)
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Life Sciences & Earth Sciences (AREA)
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Obesity (AREA)
Transplantation (AREA)
Oncology (AREA)
Vascular Medicine (AREA)
Endocrinology (AREA)
Ophthalmology & Optometry (AREA)
Emergency Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

ZA200303341A 2000-11-28 2003-04-30 Salts of a isothiazole-4-carboxamide and their use as anti-hyperproliferation agents. ZA200303341B (en)

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RU2319693C9 (ru)	1999-01-13	2008-08-20	Байер Копэрейшн	Производные мочевины (варианты), фармацевтическая композиция (варианты) и способ лечения заболевания, связанного с ростом раковых клеток (варианты)
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SI1478358T1 (sl)	2002-02-11	2013-09-30	Bayer Healthcare Llc	Sorafenib tozilat za zdravljenje bolezni, značilnih po abnormalni angiogenezi
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JP3835763B2 (ja) *	2002-08-19	2006-10-18	ファイザー・プロダクツ・インク	増殖亢進疾患のための組み合わせ治療
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JP2008510734A (ja)	2004-08-18	2008-04-10	タケダサンディエゴインコーポレイテッド	キナーゼ阻害剤
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US8119655B2 (en)	2005-10-07	2012-02-21	Takeda Pharmaceutical Company Limited	Kinase inhibitors
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US7932390B2 (en)	2006-06-29	2011-04-26	Hoffman-La Roche Inc.	Substituted thieno[3,2-C]pyridine carboxylic acid derivatives
BRPI0719883A2 (pt)	2006-10-09	2015-05-05	Takeda Pharmaceutical	Inibidores de quinase
MX2010001636A (es)	2007-08-14	2010-03-15	Hoffmann La Roche	Derivados de pirazolo[3,4-d]-pirimidina como agentes antiproliferativos.
WO2011073521A1 (en)	2009-12-15	2011-06-23	Petri Salven	Methods for enriching adult-derived endothelial progenitor cells and uses thereof
AU2011280969A1 (en)	2010-07-23	2013-02-07	Trustees Of Boston University	Anti-Despr inhibitors as therapeutics for inhibition of pathological angiogenesis and tumor cell invasiveness and for molecular imaging and targeted delivery
BR112015021334B1 (pt)	2013-03-14	2020-04-07	Panoptica Inc	formulação ocular tópica em suspenão e uso da mesma para tratamento e/ou melhora de uma doença do segmento posterior do olho
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2001
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2003
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Also Published As

Publication number	Publication date
NZ525788A (en)	2004-11-26
KR20030059275A (ko)	2003-07-07
DK1337521T3 (da)	2007-01-29
HK1059085A1 (en)	2004-06-18
NO20032388D0 (no)	2003-05-27
CA2430065A1 (en)	2002-06-06
CN1231474C (zh)	2005-12-14
EP1337521B1 (en)	2006-09-27
PL362079A1 (en)	2004-10-18
TNSN01167A1 (fr)	2005-11-10
PT1337521E (pt)	2006-12-29
IL155371A0 (en)	2003-11-23
HUP0302553A2 (hu)	2003-11-28
BG107752A (bg)	2004-01-30
SI1337521T1 (sl)	2006-12-31
YU36403A (sh)	2006-08-17
GT200100237A (es)	2002-07-03
GEP20053652B (en)	2005-11-10
HRP20030408A2 (en)	2003-08-31
SV2002000748A (es)	2002-12-02
OA12532A (en)	2006-06-02
EP1337521A1 (en)	2003-08-27
MY136686A (en)	2008-11-28
JP2008056692A (ja)	2008-03-13
IS6788A (is)	2003-04-14
JP4971946B2 (ja)	2012-07-11
UY27039A1 (es)	2002-07-31
CZ20031315A3 (cs)	2004-04-14
HUP0302553A3 (en)	2009-03-30
CR6963A (es)	2003-11-25
AU2002214204B2 (en)	2007-05-24
JP2004514714A (ja)	2004-05-20
CN1476439A (zh)	2004-02-18
BR0115621A (pt)	2003-09-02
US6831091B2 (en)	2004-12-14
HN2001000268A (es)	2002-01-30
EE200300247A (et)	2003-10-15
NO20032388L (no)	2003-07-18
DOP2001000288A (es)	2002-12-15
ATE340786T1 (de)	2006-10-15
PA8533801A1 (es)	2002-10-31
AP2001002358A0 (en)	2001-12-31
NO325187B1 (no)	2008-02-11
EA200300424A1 (ru)	2003-10-30
US20020151573A1 (en)	2002-10-17
AU1420402A (en)	2002-06-11
CA2430065C (en)	2008-05-20
MA26960A1 (fr)	2004-12-20
DE60123461T2 (de)	2007-02-15
TWI287542B (en)	2007-10-01
ECSP034628A (es)	2003-07-25
PE20020591A1 (es)	2002-07-06
MXPA03004714A (es)	2003-08-19
DE60123461D1 (de)	2006-11-09
AR031512A1 (es)	2003-09-24
WO2002044158A1 (en)	2002-06-06
ES2271086T3 (es)	2007-04-16
EA005859B1 (ru)	2005-06-30
CY1106240T1 (el)	2011-06-08
KR20050116401A (ko)	2005-12-12
SK5862003A3 (en)	2004-05-04
UA74221C2 (uk)	2005-11-15

Publication	Publication Date	Title
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AU2002214204A1 (en)	2002-08-15	Salts of a isothiazole-4-carboxamide and their use as anti-hyperproliferation agents
EP1187826B1 (en)	2006-12-27	Heterocyclic derivatives useful as anticancer agents
AP1252A (en)	2004-02-25	N-[3-ethynylphenylamino]-6.7-bis9-Methoxyethoxy)-4-quinazolinamine mesylate anhydrate and monohydrate.
HK1059085B (en)	2006-02-24	Salts of a isothiazole-4-carboxamide and their use as anti-hyperproliferation agents
WO2005110406A2 (en)	2005-11-24	Phenyl derivatives for the treatment of abnormal cell growth
HK1037180B (en)	2005-10-28	N-(3-ethynylphenylamino)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate anhydrate and monohydrate