ZA200201810B - Combined vaccine compositions. - Google Patents

Combined vaccine compositions.

Info

Publication number: ZA200201810B
Authority: ZA; South Africa
Prior art keywords: vaccine compositions; combined vaccine; combined; compositions; vaccine
Prior art date: 1999-09-07

Application number

ZA200201810A

Other languages

English (en)

Inventor

Wettendorff Martine Ann Cecile

Original Assignee

Smithkline Beecham Biolog

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-09-07

Filing date

2002-03-05

Publication date

2004-05-26

2002-03-05 Application filed by Smithkline Beecham Biolog filed Critical Smithkline Beecham Biolog

2004-05-26 Publication of ZA200201810B publication Critical patent/ZA200201810B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
- C07K16/084—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/295—Polyvalent viral antigens; Mixtures of viral and bacterial antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
- A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- B—PERFORMING OPERATIONS; TRANSPORTING
- B09—DISPOSAL OF SOLID WASTE; RECLAMATION OF CONTAMINATED SOIL
- B09C—RECLAMATION OF CONTAMINATED SOIL
- B09C1/00—Reclamation of contaminated soil
- E—FIXED CONSTRUCTIONS
- E02—HYDRAULIC ENGINEERING; FOUNDATIONS; SOIL SHIFTING
- E02D—FOUNDATIONS; EXCAVATIONS; EMBANKMENTS; UNDERGROUND OR UNDERWATER STRUCTURES
- E02D3/00—Improving or preserving soil or rock, e.g. preserving permafrost soil
- E02D3/11—Improving or preserving soil or rock, e.g. preserving permafrost soil by thermal, electrical or electro-chemical means
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20023—Virus like particles [VLP]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Virology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Microbiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Mycology (AREA)
Epidemiology (AREA)
Communicable Diseases (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Soil Sciences (AREA)
Environmental & Geological Engineering (AREA)
Structural Engineering (AREA)
Oncology (AREA)
Biotechnology (AREA)
Civil Engineering (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Agronomy & Crop Science (AREA)
Biochemistry (AREA)
General Life Sciences & Earth Sciences (AREA)
Mining & Mineral Resources (AREA)
Paleontology (AREA)
Genetics & Genomics (AREA)
General Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)

ZA200201810A 1999-09-07 2002-03-05 Combined vaccine compositions. ZA200201810B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB9921146A GB9921146D0 (en)	1999-09-07	1999-09-07	Novel composition

Publications (1)

Publication Number	Publication Date
ZA200201810B true ZA200201810B (en)	2004-05-26

Family

ID=10860520

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
ZA200306402A ZA200306402B (en)	1999-09-07	2000-09-07	Combined vaccine compositions.
ZA200201810A ZA200201810B (en)	1999-09-07	2002-03-05	Combined vaccine compositions.

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
ZA200306402A ZA200306402B (en)	1999-09-07	2000-09-07	Combined vaccine compositions.

Country Status (33)

Country	Link
US (3)	US6936255B1 (xx)
EP (3)	EP1769806A3 (xx)
JP (2)	JP4689910B2 (xx)
KR (2)	KR100594668B1 (xx)
CN (2)	CN1325117C (xx)
AR (1)	AR025502A1 (xx)
AT (2)	ATE312624T1 (xx)
AU (1)	AU766494B2 (xx)
BR (1)	BR0014171A (xx)
CA (2)	CA2384064C (xx)
CO (1)	CO5280045A1 (xx)
CY (2)	CY1107457T1 (xx)
CZ (2)	CZ302811B6 (xx)
DE (2)	DE60024893T2 (xx)
DK (2)	DK1210113T3 (xx)
ES (2)	ES2253636T3 (xx)
GB (1)	GB9921146D0 (xx)
GC (1)	GC0000201A (xx)
HK (1)	HK1048435B (xx)
HU (2)	HU229099B1 (xx)
IL (3)	IL158107A0 (xx)
MX (1)	MXPA02002484A (xx)
MY (2)	MY142842A (xx)
NO (3)	NO332800B1 (xx)
NZ (2)	NZ517621A (xx)
PL (2)	PL201767B1 (xx)
PT (1)	PT1210113E (xx)
SG (1)	SG110072A1 (xx)
SI (2)	SI1410805T1 (xx)
TR (1)	TR200200607T2 (xx)
TW (1)	TWI258374B (xx)
WO (1)	WO2001017551A2 (xx)
ZA (2)	ZA200306402B (xx)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6207646B1 (en)	1994-07-15	2001-03-27	University Of Iowa Research Foundation	Immunostimulatory nucleic acid molecules
US20060029617A1 (en) *	1997-10-03	2006-02-09	Charreyre Catherine E	Porcine circovirus and Helicobacter combination vaccines and methods of use
FR2772047B1 (fr)	1997-12-05	2004-04-09	Ct Nat D Etudes Veterinaires E	Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
ES2628744T3 (es)	1998-05-22	2017-08-03	Ottawa Hospital Research Institute	Métodos y productos para inducir inmunidad en mucosas
HU228473B1 (en)	1998-10-16	2013-03-28	Smithkline Beecham Biolog	Adjuvant systems and vaccines
US20050002958A1 (en) *	1999-06-29	2005-01-06	Smithkline Beecham Biologicals Sa	Vaccines
GB9921147D0 (en)	1999-09-07	1999-11-10	Smithkline Beecham Biolog	Novel composition
DE60126737T2 (de) *	2001-03-23	2007-11-08	Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts	Modifizierte HPV E6- und E7-Gene und -Proteine als Impfstoff
GB0110431D0 (en) *	2001-04-27	2001-06-20	Glaxosmithkline Biolog Sa	Novel compounds
GB0206360D0 (en)	2002-03-18	2002-05-01	Glaxosmithkline Biolog Sa	Viral antigens
JP4614765B2 (ja) †	2002-05-17	2011-01-19	ユニバーシティ・オブ・ケープ・タウン	Ｌ２ペプチドを含むキメラ・ヒト・パピローマウイルス１６ｌ１タンパク質、それから調製したウイルス様粒子および該粒子の調製方法
CN1650012A (zh)	2002-07-24	2005-08-03	英特塞尔股份公司	来自致病病毒的备选阅读框所编码的抗原
WO2004024182A2 (en)	2002-09-13	2004-03-25	Intercell Ag	Method for isolating hepatitis c virus peptides
JP2006515277A (ja)	2002-10-29	2006-05-25	コーリーファーマシューティカルグループ，リミテッド	Ｃ型肝炎ウィルス感染の処置および予防に関する方法および製品
CA2502015A1 (en)	2002-12-11	2004-06-24	Coley Pharmaceutical Group, Inc.	5' cpg nucleic acids and methods of use
US7858098B2 (en) *	2002-12-20	2010-12-28	Glaxosmithkline Biologicals, S.A.	Vaccine
OA13147A (en) *	2002-12-20	2006-12-13	Glaxosmithkline Biolog Sa	HPV-16 and -18 L1 VLP vaccine.
UA85377C2 (ru) *	2002-12-20	2009-01-26	Глаксосмітклайн Байолоджикалз Са	Применение композиции, содержащей вирусоподобные частички hpv16 і hpv18 при приготовлении медикамента для профилактики инфекции и/или болезни, вызванной группой hpv онкогенных типов, способы индуцирования иммунной реакции, профилактики инфекции и/или болезни, профилактики в популяции субъектов инфекции вызванных одной или несколькими группами онкогенных типов hpv, вакцинная композиция, которая включает hpv16 і нр18
CA2519922A1 (en) *	2003-03-24	2004-10-07	Intercell Ag	Use of alum and a th1 immune response inducing adjuvant for enhancing immune responses
DE602004029657D1 (de) *	2003-03-24	2010-12-02	Intercell Ag	Verbesserte impfstoffe
GB0413510D0 (en) *	2004-06-16	2004-07-21	Glaxosmithkline Biolog Sa	Vaccine
US7758866B2 (en)	2004-06-16	2010-07-20	Glaxosmithkline Biologicals, S.A.	Vaccine against HPV16 and HPV18 and at least another HPV type selected from HPV 31, 45 or 52
CA2566620C (en) *	2004-06-16	2014-03-11	Glaxosmithkline Biologicals S.A.	Vaccine against hpv16 and hpv18 and at least another hpv type slected from hpv 31, 45 or 52
US7833707B2 (en)	2004-12-30	2010-11-16	Boehringer Ingelheim Vetmedica, Inc.	Methods of overexpression and recovery of porcine circovirus type 2 ORF2
NZ560930A (en) *	2005-02-16	2011-06-30	Novartis Vaccines & Diagnostic	Hepatitis B virus vaccine comprising a hepatitis B virus surface antigen, aluminium phosphate, 3-O-deacylated monophosphoryl lipid A and a triethylammonium ion
JP4182074B2 (ja)	2005-03-03	2008-11-19	ファナック株式会社	ハンド及びハンドリングロボット
WO2006100109A1 (en) *	2005-03-23	2006-09-28	Glaxosmithkline Biologicals S.A.	Use of an influenza virus an oil-in-water emulsion adjuvant to induce cd4 t-cell and/or improved b-memory cell response
CA2606092A1 (en) *	2005-04-26	2006-11-02	Glaxosmithkline Biologicals S.A.	Vaccine
AU2006239471A1 (en) *	2005-04-26	2006-11-02	Glaxosmithkline Biologicals S.A.	Vaccine
TWI457133B (zh)	2005-12-13	2014-10-21	Glaxosmithkline Biolog Sa	新穎組合物
US7790203B2 (en) *	2005-12-13	2010-09-07	Lowder Tom R	Composition and regimen for the treatment of herpes simplex virus, herpes zoster, and herpes genitalia epidermal herpetic lesions
PL3320919T3 (pl)	2005-12-29	2020-11-30	Boehringer Ingelheim Animal Health USA Inc.	Multiwalentne immunogenne kompozycje PCV2 i sposoby wytwarzania takich kompozycji
CN101426522B (zh)	2005-12-29	2014-11-12	贝林格尔.英格海姆维特梅迪卡有限公司	Pcv2免疫原性组合物用于减轻猪临床症状的用途
US20090246220A1 (en)	2006-08-28	2009-10-01	Ertl Hildegund C J	Constructs for enhancing immune responses
HUE037808T2 (hu)	2006-09-26	2018-09-28	Infectious Disease Res Inst	Szintetikus adalékanyagot tartalmazó vakcina kompozíció
US20090181078A1 (en)	2006-09-26	2009-07-16	Infectious Disease Research Institute	Vaccine composition containing synthetic adjuvant
EP1941903A1 (en)	2007-01-03	2008-07-09	Boehringer Ingelheim Vetmedica Gmbh	Prophylaxis and treatment of PRDC
EP1958644A1 (en)	2007-02-13	2008-08-20	Boehringer Ingelheim Vetmedica Gmbh	Prevention and treatment of sub-clinical pcvd
US7709010B2 (en)	2007-03-09	2010-05-04	Merck Sharp & Dohme Corp.	Papillomavirus vaccine compositions
KR101624358B1 (ko)	2007-06-26	2016-05-26	고에키자이단호진 휴먼 사이언스 신코우자이단	고리스크군 인간 파필로마 바이러스에 대한 교차성 중화 항체를 유도하는 백신 항원
US7829274B2 (en)	2007-09-04	2010-11-09	Boehringer Ingelheim Vetmedica, Inc.	Reduction of concomitant infections in pigs by the use of PCV2 antigen
EP2298344B1 (en)	2008-06-04	2016-08-17	The Chemo-Sero-Therapeutic Research Institute	Use of inactivated japanese encephalitis virus particle as adjuvant
BRPI0916732B1 (pt) *	2008-07-31	2021-06-29	Glaxosmithkline Biologicals S.A.	Vacina para a prevenção de doença ou infecção relacionada ao papilomavirus humano (hpv) compreendendo partículas semelhantes ao vírus hpv 16 e hpv 18
EP3590533A1 (en)	2009-05-22	2020-01-08	Genocea Biosciences, Inc.	Vaccines against herpes simplex virus type 2: compositions and methods for eliciting an immune response
TWI549688B (zh)	2009-06-05	2016-09-21	美國疾病傳染研究機構	合成的葡萄吡喃糖基脂質佐劑
PL2444103T3 (pl) *	2009-06-19	2018-05-30	Eyegene Inc.	Szczepionka przeciwko rakowi szyjki macicy
US20120087937A1 (en) *	2009-06-25	2012-04-12	Brigitte Desiree Alberte Colau	Novel compositions
TWI627281B (zh)	2009-09-02	2018-06-21	百靈佳殷格翰家畜藥品公司	降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物
CA2800158C (en) *	2010-05-28	2020-07-21	Coley Pharmaceutical Group, Inc.	Vaccines comprising cholesterol and cpg as sole adjuvant-carrier molecules
UA112970C2 (uk) *	2010-08-05	2016-11-25	Мерк Шарп Енд Доме Корп.	Інактивований вірус вітряної віспи, спосіб його одержання і застосування
EP2609428B1 (en) *	2010-08-27	2016-02-10	Intervet International B.V.	Potency test for vaccine formulations
CN102008721A (zh) *	2010-11-16	2011-04-13	浙江大学	一种hpv多肽/dc混合疫苗及其制备
AU2011336894B2 (en)	2010-11-24	2016-11-17	Genocea Biosciences, Inc.	Vaccines against Herpes Simplex Virus type 2: compositions and methods for eliciting an immune response
WO2012141984A1 (en)	2011-04-08	2012-10-18	Immune Design Corp.	Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses
CN102210858B (zh) *	2011-05-18	2013-05-08	北京科兴生物制品有限公司	一种肠道病毒71型与甲型肝炎联合疫苗
KR102049988B1 (ko) *	2011-06-24	2019-11-28	머크 샤프 앤드 돔 코포레이션	알루미늄 아주반트를 포함하는 hpv 백신 제제 및 그의 제조 방법
JP6109165B2 (ja) *	2011-07-01	2017-04-05	ザリージェンツオブザユニバーシティオブカリフォルニア	ヘルペスウイルスワクチンおよび使用方法
AU2012340712B2 (en)	2011-11-23	2017-09-14	Genocea Biosciences, Inc.	Nucleic acid vaccines against Herpes Simplex Virus type 2: compositions and methods for eliciting an immune response
HRP20190960T1 (hr)	2012-02-07	2019-07-26	Infectious Disease Research Institute	Poboljšane adjuvantne formulacije koje sadrže agoniste tlr4 i postupci njihove upotrebe
HRP20181102T1 (hr)	2012-05-16	2018-09-07	Immune Design Corp	Cjepiva za hsv-2
US9624510B2 (en)	2013-03-01	2017-04-18	The Wistar Institute	Adenoviral vectors comprising partial deletions of E3
EA032326B1 (ru)	2013-04-18	2019-05-31	Иммьюн Дизайн Корп.	Монотерапия gla для применения в лечении рака
US9463198B2 (en)	2013-06-04	2016-10-11	Infectious Disease Research Institute	Compositions and methods for reducing or preventing metastasis
IL310015B1 (en)	2013-12-31	2025-10-01	Access To Advanced Health Inst	Single vial formulation
EP3490610A4 (en)	2016-08-01	2020-05-20	The Wistar Institute Of Anatomy And Biology	Compositions and methods of replication deficient adenoviral vectors for vaccine applications
US10350288B2 (en)	2016-09-28	2019-07-16	Genocea Biosciences, Inc.	Methods and compositions for treating herpes
CN107987159B (zh) *	2017-11-28	2021-06-22	上海药明生物医药有限公司	一种使用大剂量dna免疫技术免疫动物使血清中抗体滴度提高的方法
GB201821207D0 (en) *	2018-12-24	2019-02-06	Tcer Ab	Immunotherapy therapy
MX2021014363A (es)	2019-05-25	2022-02-21	Infectious Disease Res Inst	Composicion y metodo para secar por pulverizacion una emulsion de vacuna adyuvante.
CN110576034B (zh) *	2019-10-09	2020-06-30	北京尚华生态环保科技股份公司	一种土壤原位修复方法
CN110652980B (zh) *	2019-10-09	2020-06-30	北京尚华生态环保科技股份公司	一种土壤原位修复剂
WO2021097347A1 (en)	2019-11-15	2021-05-20	Infectious Disease Research Institute	Rig-i agonist and adjuvant formulation for tumor treatment
CN114681602B (zh) *	2020-12-25	2023-12-01	中国食品药品检定研究院	一种双价人乳头瘤病毒疫苗
CN114796479A (zh) *	2022-06-02	2022-07-29	金宇保灵生物药品有限公司	一种畜类动物疫苗用水包油包水佐剂及其制备方法和应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH085804B2 (ja)	1988-04-28	1996-01-24	財団法人化学及血清療法研究所	Ａ型及びｂ型肝炎混合アジュバントワクチン
GB9113809D0 (en) *	1991-06-26	1991-08-14	Cancer Res Campaign Tech	Papillomavirus l2 protein
DE122007000023I1 (de) *	1991-07-19	2007-08-09	Univ Queensland St Lucia	Impfsstoff gegen Humanes Papillomavirus (typ 18)
US5618536A (en) *	1992-09-03	1997-04-08	The United States Of America As Represented By The Department Of Health And Human Services	Chimeric papillomavirus-like particles
US5437951A (en) *	1992-09-03	1995-08-01	The United States Of America As Represented By The Department Of Health And Human Services	Self-assembling recombinant papillomavirus capsid proteins
US5776468A (en) *	1993-03-23	1998-07-07	Smithkline Beecham Biologicals (S.A.)	Vaccine compositions containing 3-0 deacylated monophosphoryl lipid A
GB9326253D0 (en) *	1993-12-23	1994-02-23	Smithkline Beecham Biolog	Vaccines
GB9409962D0 (en) *	1994-05-18	1994-07-06	Smithkline Beecham Biolog	Novel compounds
AU4727296A (en) *	1995-02-24	1996-09-11	Cantab Pharmaceuticals Research Limited	Polypeptides useful as immunotherapeutic agents and methods of polypeptide preparation
WO1997027300A1 (en) *	1996-01-26	1997-07-31	Innogenetics N.V.	TOXOPLASMA GONDII ANTIGEN Tg20
CN1210470A (zh) *	1996-02-09	1999-03-10	史密斯克莱·比奇曼生物公司	抗水痘－带状疱疹病毒基因63产物的疫苗
GB9711990D0 (en) *	1997-06-11	1997-08-06	Smithkline Beecham Biolog	Vaccine
GB9717953D0 (en) *	1997-08-22	1997-10-29	Smithkline Beecham Biolog	Vaccine
CA2229955C (en) *	1998-02-20	2003-12-09	Medigene Gmbh	Papilloma virus capsomere vaccine formulations and methods of use
PL343429A1 (en) *	1998-03-09	2001-08-13	Smithkline Beecham Biolog	Combined vaccine compositions
US6500284B1 (en)	1998-06-10	2002-12-31	Suraltech, Inc.	Processes for continuously producing fine grained metal compositions and for semi-solid forming of shaped articles
GB9819898D0 (en)	1998-09-11	1998-11-04	Smithkline Beecham Plc	New vaccine and method of use
HU228473B1 (en)	1998-10-16	2013-03-28	Smithkline Beecham Biolog	Adjuvant systems and vaccines
EP1150712B1 (en) *	1999-02-05	2008-11-05	Merck & Co., Inc.	Human papilloma virus vaccine formulations
GB9921147D0 (en) *	1999-09-07	1999-11-10	Smithkline Beecham Biolog	Novel composition

1999
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Also Published As

Publication number	Publication date
JP2004067696A (ja)	2004-03-04
SG110072A1 (en)	2005-04-28
US7101560B2 (en)	2006-09-05
JP2003508495A (ja)	2003-03-04
CN100389824C (zh)	2008-05-28
AU7775100A (en)	2001-04-10
PL201767B1 (pl)	2009-05-29
MY130084A (en)	2007-05-31
AR025502A1 (es)	2002-11-27
EP1769806A3 (en)	2007-10-24
HK1064958A1 (en)	2005-02-08
TW200408405A (en)	2004-06-01
CY1106090T1 (el)	2011-06-08
DE60024893D1 (de)	2006-01-19
CA2384064C (en)	2010-06-01
NO2012016I1 (no)	2012-10-15
SI1210113T1 (sl)	2006-08-31
NO332800B1 (no)	2013-01-14
KR20020027630A (ko)	2002-04-13
EP1210113B1 (en)	2006-03-29
HU0303215D0 (en)	2003-11-28
IL148456A0 (en)	2002-09-12
HK1048435B (en)	2007-01-05
NO20033715L (no)	2002-04-30
CA2443214C (en)	2006-03-21
CZ2002843A3 (cs)	2002-08-14
AU766494B2 (en)	2003-10-16
EP1410805B1 (en)	2005-12-14
KR20030087081A (ko)	2003-11-12
NO2012016I2 (no)	2012-10-08
HUP0202804A2 (hu)	2002-12-28
IL158107A0 (en)	2004-03-28
US20060280756A1 (en)	2006-12-14
HU229099B1 (en)	2013-07-29
NZ527560A (en)	2004-12-24
US7220551B2 (en)	2007-05-22
ES2253636T3 (es)	2006-06-01
MXPA02002484A (es)	2002-08-28
US20040126394A1 (en)	2004-07-01
KR100594668B1 (ko)	2006-06-30
WO2001017551A3 (en)	2001-09-27
WO2001017551A2 (en)	2001-03-15
CN1325117C (zh)	2007-07-11
ATE321569T1 (de)	2006-04-15
DE60027029D1 (de)	2006-05-18
HUP0303215A3 (en)	2008-04-28
NZ517621A (en)	2003-09-26
CA2384064A1 (en)	2001-03-15
CA2443214A1 (en)	2001-03-15
PL354039A1 (en)	2003-12-15
DE60024893T2 (de)	2006-07-06
KR100557665B1 (ko)	2006-03-06
DK1410805T3 (da)	2006-04-18
EP1769806A2 (en)	2007-04-04
SI1410805T1 (sl)	2006-04-30
CN1618465A (zh)	2005-05-25
HU228687B1 (en)	2013-05-28
TR200200607T2 (tr)	2002-06-21
TWI258374B (en)	2006-07-21
NO20033715D0 (no)	2003-08-21
EP1410805A1 (en)	2004-04-21
NO20021116L (no)	2002-04-30
DE60027029T2 (de)	2006-10-19
NO20021116D0 (no)	2002-03-06
IL158107A (en)	2008-11-03
HK1048435A1 (en)	2003-04-04
ES2261243T3 (es)	2006-11-16
CO5280045A1 (es)	2003-05-30
PT1210113E (pt)	2006-07-31
ZA200306402B (en)	2004-08-02
GB9921146D0 (en)	1999-11-10
CN1387443A (zh)	2002-12-25
CY1107457T1 (el)	2012-12-19
EP1210113A2 (en)	2002-06-05
MY142842A (en)	2011-01-14
ATE312624T1 (de)	2005-12-15
CZ302811B6 (cs)	2011-11-23
HUP0202804A3 (en)	2004-08-30
DK1210113T3 (da)	2006-07-03
PL201264B1 (pl)	2009-03-31
NO331825B1 (no)	2012-04-10
BR0014171A (pt)	2002-05-21
JP4689910B2 (ja)	2011-06-01
GC0000201A (en)	2006-03-29
US6936255B1 (en)	2005-08-30

Publication	Publication Date	Title
ZA200201810B (en)	2004-05-26	Combined vaccine compositions.
EG24742A (en)	2010-07-14	Vaccine composition.
HUP0203056A3 (en)	2008-04-28	Vaccine composition
ZA200004956B (en)	2002-02-27	Vaccine composition.
ZA200003997B (en)	2000-08-14	Pharmaceutical compositions.
MXPA03008961A (es)	2004-02-12	Composicion de vacuna.
PL343429A1 (en)	2001-08-13	Combined vaccine compositions
MXPA01010676A (es)	2003-08-20	Composicion farmaceutica de vitamina d o un analogo de vitamina d y al menos un corticoesteroide.
ZA200108687B (en)	2003-03-26	Enhanced herbicide compositions.
GB9910812D0 (en)	1999-07-07	Vaccine composition
ZA200203486B (en)	2003-08-04	Novel pharmaceutical compositions.
ZA200108248B (en)	2002-12-24	Antiperspirant compositions.
MXPA01012478A (es)	2003-10-14	Formulaciones farmaceuticas mejoradas.
ZA200107149B (en)	2003-02-28	Valdecoxib compositions.
ZA200210359B (en)	2003-11-13	Pharmaceutical compositions.
ZA200000857B (en)	2001-05-31	Pharmaceutical composition.
MXPA03002105A (es)	2003-06-19	Composiciones farmaceuticas.
MXPA01010701A (es)	2003-08-20	Vacuna.
ZA200108844B (en)	2002-12-24	Fungicidal compositions.
ZA984696B (en)	1999-01-04	Vaccine compositions V.
AU1101701A (en)	2001-05-08	Vaccine compositions
GB9921347D0 (en)	1999-11-10	Novel immunogenic compositions
ZA200203986B (en)	2003-12-17	Vaccine compositions.
ZA200006204B (en)	2001-05-21	Polurethane/polyurea-forming compositions.
GB9929434D0 (en)	2000-02-09	Novel vaccine composition