[go: up one dir, main page]

SG110072A1 - Novel composition - Google Patents

Novel composition

Info

Publication number
SG110072A1
SG110072A1 SG200305672A SG200305672A SG110072A1 SG 110072 A1 SG110072 A1 SG 110072A1 SG 200305672 A SG200305672 A SG 200305672A SG 200305672 A SG200305672 A SG 200305672A SG 110072 A1 SG110072 A1 SG 110072A1
Authority
SG
Singapore
Prior art keywords
novel composition
novel
composition
Prior art date
Application number
SG200305672A
Inventor
Martine Anne Cecil Wettendorff
Original Assignee
Smithkline Beecham Biolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Biolog filed Critical Smithkline Beecham Biolog
Publication of SG110072A1 publication Critical patent/SG110072A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/084Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/295Polyvalent viral antigens; Mixtures of viral and bacterial antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • A61K39/292Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B09DISPOSAL OF SOLID WASTE; RECLAMATION OF CONTAMINATED SOIL
    • B09CRECLAMATION OF CONTAMINATED SOIL
    • B09C1/00Reclamation of contaminated soil
    • EFIXED CONSTRUCTIONS
    • E02HYDRAULIC ENGINEERING; FOUNDATIONS; SOIL SHIFTING
    • E02DFOUNDATIONS; EXCAVATIONS; EMBANKMENTS; UNDERGROUND OR UNDERWATER STRUCTURES
    • E02D3/00Improving or preserving soil or rock, e.g. preserving permafrost soil
    • E02D3/11Improving or preserving soil or rock, e.g. preserving permafrost soil by thermal, electrical or electro-chemical means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5258Virus-like particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20023Virus like particles [VLP]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Soil Sciences (AREA)
  • Molecular Biology (AREA)
  • Structural Engineering (AREA)
  • Environmental & Geological Engineering (AREA)
  • Oncology (AREA)
  • Paleontology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • Biotechnology (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • Mining & Mineral Resources (AREA)
  • Biochemistry (AREA)
  • Civil Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG200305672A 1999-09-07 2000-09-07 Novel composition SG110072A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9921146A GB9921146D0 (en) 1999-09-07 1999-09-07 Novel composition

Publications (1)

Publication Number Publication Date
SG110072A1 true SG110072A1 (en) 2005-04-28

Family

ID=10860520

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200305672A SG110072A1 (en) 1999-09-07 2000-09-07 Novel composition

Country Status (33)

Country Link
US (3) US6936255B1 (en)
EP (3) EP1769806A3 (en)
JP (2) JP4689910B2 (en)
KR (2) KR100594668B1 (en)
CN (2) CN1325117C (en)
AR (1) AR025502A1 (en)
AT (2) ATE312624T1 (en)
AU (1) AU766494B2 (en)
BR (1) BR0014171A (en)
CA (2) CA2384064C (en)
CO (1) CO5280045A1 (en)
CY (2) CY1107457T1 (en)
CZ (2) CZ302811B6 (en)
DE (2) DE60027029T2 (en)
DK (2) DK1210113T3 (en)
ES (2) ES2253636T3 (en)
GB (1) GB9921146D0 (en)
GC (1) GC0000201A (en)
HK (1) HK1048435B (en)
HU (2) HU229099B1 (en)
IL (3) IL158107A0 (en)
MX (1) MXPA02002484A (en)
MY (2) MY142842A (en)
NO (3) NO332800B1 (en)
NZ (2) NZ527560A (en)
PL (2) PL201264B1 (en)
PT (1) PT1210113E (en)
SG (1) SG110072A1 (en)
SI (2) SI1410805T1 (en)
TR (1) TR200200607T2 (en)
TW (1) TWI258374B (en)
WO (1) WO2001017551A2 (en)
ZA (2) ZA200306402B (en)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6207646B1 (en) 1994-07-15 2001-03-27 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US20060029617A1 (en) * 1997-10-03 2006-02-09 Charreyre Catherine E Porcine circovirus and Helicobacter combination vaccines and methods of use
FR2772047B1 (en) 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E GENOMIC SEQUENCE AND POLYPEPTIDES OF CIRCOVIRUS ASSOCIATED WITH PIGLET LOSS DISEASE (MAP), APPLICATIONS TO DIAGNOSIS AND TO PREVENTION AND / OR TREATMENT OF INFECTION
DE69932717T2 (en) 1998-05-22 2007-08-09 Ottawa Health Research Institute, Ottawa METHODS AND PRODUCTS FOR INDUCING MUCOSAL IMMUNITY
CN101926993B (en) 1998-10-16 2013-12-04 史密丝克莱恩比彻姆生物有限公司 Adjuvant systems and vaccines
US20050002958A1 (en) * 1999-06-29 2005-01-06 Smithkline Beecham Biologicals Sa Vaccines
GB9921147D0 (en) 1999-09-07 1999-11-10 Smithkline Beecham Biolog Novel composition
EP1243655B1 (en) * 2001-03-23 2007-02-21 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Modified HPV E6 and E7 genes and proteins useful for vaccination
GB0110431D0 (en) * 2001-04-27 2001-06-20 Glaxosmithkline Biolog Sa Novel compounds
GB0206360D0 (en) * 2002-03-18 2002-05-01 Glaxosmithkline Biolog Sa Viral antigens
DE60326449D1 (en) 2002-05-17 2009-04-16 Univ Cape Town CHIMERIC HUMAN PAPILLOMA VIRUS 16 L1 PROTEINS CONTAINING A L2 PEPTIDE, THEREFORE MANUFACTURED VIRUS-SIMILAR PARTICLES AND METHOD FOR THE PRODUCTION OF PARTICLES
CN1650012A (en) 2002-07-24 2005-08-03 英特塞尔股份公司 Antigens encoded by alternative reading frames from pathogenic viruses
JP2006504687A (en) 2002-09-13 2006-02-09 インターツェル・アクチェンゲゼルシャフト Method for isolating hepatitis C virus peptide
DK2241325T3 (en) 2002-10-29 2012-04-10 Coley Pharm Group Inc Use of CPG oligonucleotides to treat Hepatitis Cvirus infection
AU2003300919A1 (en) 2002-12-11 2004-06-30 Coley Pharmaceutical Gmbh 5' cpg nucleic acids and methods of use
CN100418577C (en) * 2002-12-20 2008-09-17 葛兰素史密丝克莱恩生物有限公司 Hpv-16 and -18 l1 vlp vaccine.
US7858098B2 (en) * 2002-12-20 2010-12-28 Glaxosmithkline Biologicals, S.A. Vaccine
WO2004056389A1 (en) * 2002-12-20 2004-07-08 Glaxosmithkline Biologicals Sa Hpv-16 and -18 l1 vlp vaccine
CN100355453C (en) * 2003-03-24 2007-12-19 英特塞尔股份公司 Improved vaccines
EP1608402B1 (en) 2003-03-24 2010-10-20 Intercell AG Improved vaccines
RU2420313C2 (en) * 2004-06-16 2011-06-10 ГлаксоСмитКлайн Байолоджикалз с.а. Vaccine against human papilloma viruses hpv16 and hpv18 and at least one more type hpv, selected from hpv 31,45 or 52
US7758866B2 (en) * 2004-06-16 2010-07-20 Glaxosmithkline Biologicals, S.A. Vaccine against HPV16 and HPV18 and at least another HPV type selected from HPV 31, 45 or 52
GB0413510D0 (en) * 2004-06-16 2004-07-21 Glaxosmithkline Biolog Sa Vaccine
US7833707B2 (en) 2004-12-30 2010-11-16 Boehringer Ingelheim Vetmedica, Inc. Methods of overexpression and recovery of porcine circovirus type 2 ORF2
EA012212B1 (en) * 2005-02-16 2009-08-28 Новартис Вэксинес Энд Дайэгностикс, Инк. Adjuvant composition comprising aluminium phosphate and 3d-mpl
JP4182074B2 (en) 2005-03-03 2008-11-19 ファナック株式会社 Hand and handling robot
PE20061428A1 (en) * 2005-03-23 2007-01-16 Glaxosmithkline Biolog Sa VACCINE FORMULATION INCLUDING AN OIL EMULSION ADJUVANT IN WATER AND 3D-MPL
CA2606092A1 (en) * 2005-04-26 2006-11-02 Glaxosmithkline Biologicals S.A. Vaccine
WO2006114273A2 (en) * 2005-04-26 2006-11-02 Glaxosmithkline Biologicals S.A. Vaccine
US7790203B2 (en) * 2005-12-13 2010-09-07 Lowder Tom R Composition and regimen for the treatment of herpes simplex virus, herpes zoster, and herpes genitalia epidermal herpetic lesions
TWI457133B (en) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa Novel composition
RU2488407C2 (en) 2005-12-29 2013-07-27 Берингер Ингельхайм Ветмедика, Инк. Polyvalent immunogenic compositions pcv2 and methods for producing such compositions
DK2371383T3 (en) 2005-12-29 2015-11-30 Boehringer Ingelheim Vetmed Use of a PCV2 immunogenic composition for reduction of clinical symptoms in pigs
WO2008027394A2 (en) 2006-08-28 2008-03-06 The Wistar Institute Of Anatomy And Biology Constructs for enhancing immune responses
ES2657392T3 (en) 2006-09-26 2018-03-05 Infectious Disease Research Institute Vaccine composition containing a synthetic adjuvant
US20090181078A1 (en) 2006-09-26 2009-07-16 Infectious Disease Research Institute Vaccine composition containing synthetic adjuvant
EP1941903A1 (en) 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxis and treatment of PRDC
EP1958644A1 (en) 2007-02-13 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Prevention and treatment of sub-clinical pcvd
JP2010520874A (en) 2007-03-09 2010-06-17 メルク・シャープ・エンド・ドーム・コーポレイション Papillomavirus vaccine composition
RU2471807C2 (en) * 2007-06-26 2013-01-10 Джапан Хелт Сайенсес Фаундейшн Vaccine antigen capable of inducing cross-reacting and neutralising antibody against high-risk-type human papillomavirus
US7829274B2 (en) 2007-09-04 2010-11-09 Boehringer Ingelheim Vetmedica, Inc. Reduction of concomitant infections in pigs by the use of PCV2 antigen
EP2298344B1 (en) 2008-06-04 2016-08-17 The Chemo-Sero-Therapeutic Research Institute Use of inactivated japanese encephalitis virus particle as adjuvant
HRP20141063T1 (en) * 2008-07-31 2015-01-02 Glaxosmithkline Biologicals S.A. HPV Vaccine
ES2732815T3 (en) 2009-05-22 2019-11-26 Genocea Biosciences Inc Vaccines against herpes simplex virus type 2: compositions and methods to elicit an immune response
PT2437753T (en) 2009-06-05 2016-11-23 Infectious Disease Res Inst Synthetic glucopyranosyl lipid adjuvants and vaccine compositions containing them
CN102215861B (en) * 2009-06-19 2014-10-08 艾金株式会社 Vaccine for cervical cancer
KR20120098580A (en) * 2009-06-25 2012-09-05 글락소스미스클라인 바이오로지칼즈 에스.에이. Novel human papillomavirus(hpv) protein constructs and their use in the prevention of hpv disease
TWI627281B (en) 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 Methods of reducing viricidal activity in pcv-2 compositions and pcv-2 compositions with an improved immunogenicity
CN103025351B (en) * 2010-05-28 2016-08-24 佐蒂斯比利时股份有限公司 Comprise cholesterol and the vaccine of the CPG as unique adjuvant-supporting agent molecule
UA112970C2 (en) * 2010-08-05 2016-11-25 Мерк Шарп Енд Доме Корп. INITIATED WINDOW ISLAND VIRUS, METHOD OF ITS RECEIVING AND APPLICATION
BR112013004594B1 (en) * 2010-08-27 2020-07-28 Intervet International B. V. method for determining an antigen content
CN102008721A (en) * 2010-11-16 2011-04-13 浙江大学 HPV (human papillomavirus) peptide/DC (dendritic cell) mixed vaccine and preparation thereof
CA2856697A1 (en) 2010-11-24 2012-06-07 Genocea Biosciences, Inc. Vaccines against herpes simplex virus type 2: compositions and methods for eliciting an immune response
EP3632463A1 (en) 2011-04-08 2020-04-08 Immune Design Corp. Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses
CN102210858B (en) * 2011-05-18 2013-05-08 北京科兴生物制品有限公司 Combined EV71 (enterovirus 71)-HA (hepatitis A) vaccine
JP6050811B2 (en) 2011-06-24 2016-12-21 メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. HPV vaccine preparation containing aluminum adjuvant and production method thereof
JP6109165B2 (en) * 2011-07-01 2017-04-05 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア Herpesvirus vaccines and methods of use
AU2012340712B2 (en) 2011-11-23 2017-09-14 Genocea Biosciences, Inc. Nucleic acid vaccines against Herpes Simplex Virus type 2: compositions and methods for eliciting an immune response
RS58868B1 (en) 2012-02-07 2019-08-30 Infectious Disease Res Inst Improved adjuvant formulations comprising tlr4 agonists and methods of using the same
SMT201800368T1 (en) 2012-05-16 2018-09-13 Immune Design Corp Vaccines for hsv-2
US9624510B2 (en) 2013-03-01 2017-04-18 The Wistar Institute Adenoviral vectors comprising partial deletions of E3
EP3711768A1 (en) 2013-04-18 2020-09-23 Immune Design Corp. Gla monotherapy for use in cancer treatment
US9463198B2 (en) 2013-06-04 2016-10-11 Infectious Disease Research Institute Compositions and methods for reducing or preventing metastasis
IL310015B1 (en) 2013-12-31 2025-10-01 Access To Advanced Health Inst Single vial vaccine formulations
AU2017305176B2 (en) 2016-08-01 2021-05-27 The Wistar Institute Of Anatomy And Biology Compositions and methods of replication deficient adenoviral vectors for vaccine applications
JP2019537555A (en) 2016-09-28 2019-12-26 ジェノセア バイオサイエンシーズ, インコーポレイテッド Methods and compositions for treating herpes
CN107987159B (en) * 2017-11-28 2021-06-22 上海药明生物医药有限公司 Method for improving antibody titer in serum by immunizing animal with high-dose DNA immunization technology
GB201821207D0 (en) * 2018-12-24 2019-02-06 Tcer Ab Immunotherapy therapy
BR112021023726A2 (en) 2019-05-25 2022-02-15 Infectious Disease Res Inst Composition and method for spray drying an adjuvant vaccine emulsion
CN110576034B (en) * 2019-10-09 2020-06-30 北京尚华生态环保科技股份公司 Soil in-situ remediation method
CN110652980B (en) * 2019-10-09 2020-06-30 北京尚华生态环保科技股份公司 A soil in situ remediation agent
EP4058581A1 (en) 2019-11-15 2022-09-21 Infectious Disease Research Institute Rig-i agonist and adjuvant formulation for tumor treatment
CN114681602B (en) * 2020-12-25 2023-12-01 中国食品药品检定研究院 Bivalent human papillomavirus vaccine
CN114796479A (en) * 2022-06-02 2022-07-29 金宇保灵生物药品有限公司 Water-in-oil-in-water adjuvant for livestock vaccine and preparation method and application thereof

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH085804B2 (en) 1988-04-28 1996-01-24 財団法人化学及血清療法研究所 Hepatitis A and B mixed adjuvant vaccine
GB9113809D0 (en) * 1991-06-26 1991-08-14 Cancer Res Campaign Tech Papillomavirus l2 protein
DE122007000023I1 (en) * 1991-07-19 2007-08-09 Univ Queensland St Lucia Vaccine against human papillomavirus (type 18)
US5437951A (en) * 1992-09-03 1995-08-01 The United States Of America As Represented By The Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
US5618536A (en) * 1992-09-03 1997-04-08 The United States Of America As Represented By The Department Of Health And Human Services Chimeric papillomavirus-like particles
AU685443B2 (en) 1993-03-23 1998-01-22 Smithkline Beecham Biologicals (Sa) Vaccine compositions containing 3-O deacylated monophosphoryl lipid A
GB9326253D0 (en) * 1993-12-23 1994-02-23 Smithkline Beecham Biolog Vaccines
GB9409962D0 (en) * 1994-05-18 1994-07-06 Smithkline Beecham Biolog Novel compounds
JP3958360B2 (en) * 1995-02-24 2007-08-15 キャンタブ ファーマシューティカルズ リサーチ リミティド Polypeptides useful as immunotherapeutic agents and methods of polypeptide preparation
CA2242200A1 (en) * 1996-01-26 1997-07-31 Innogenetics N.V. Toxoplasma gondii antigen tg20
WO1997028820A1 (en) * 1996-02-09 1997-08-14 Smithkline Beecham Biologicals S.A. Vaccines against varicella zoster virus gene 63 product
GB9711990D0 (en) * 1997-06-11 1997-08-06 Smithkline Beecham Biolog Vaccine
GB9717953D0 (en) * 1997-08-22 1997-10-29 Smithkline Beecham Biolog Vaccine
CA2229955C (en) * 1998-02-20 2003-12-09 Medigene Gmbh Papilloma virus capsomere vaccine formulations and methods of use
KR20010041629A (en) 1998-03-09 2001-05-25 장 스테판느 Combined vaccine compositions
US6500284B1 (en) 1998-06-10 2002-12-31 Suraltech, Inc. Processes for continuously producing fine grained metal compositions and for semi-solid forming of shaped articles
GB9819898D0 (en) 1998-09-11 1998-11-04 Smithkline Beecham Plc New vaccine and method of use
CN101926993B (en) 1998-10-16 2013-12-04 史密丝克莱恩比彻姆生物有限公司 Adjuvant systems and vaccines
EP1150712B1 (en) * 1999-02-05 2008-11-05 Merck & Co., Inc. Human papilloma virus vaccine formulations
GB9921147D0 (en) * 1999-09-07 1999-11-10 Smithkline Beecham Biolog Novel composition

Also Published As

Publication number Publication date
MY130084A (en) 2007-05-31
TWI258374B (en) 2006-07-21
EP1210113A2 (en) 2002-06-05
US7220551B2 (en) 2007-05-22
CZ302811B6 (en) 2011-11-23
HU229099B1 (en) 2013-07-29
JP4689910B2 (en) 2011-06-01
DK1210113T3 (en) 2006-07-03
AR025502A1 (en) 2002-11-27
IL158107A (en) 2008-11-03
GB9921146D0 (en) 1999-11-10
KR100557665B1 (en) 2006-03-06
CO5280045A1 (en) 2003-05-30
NO331825B1 (en) 2012-04-10
JP2004067696A (en) 2004-03-04
PL201767B1 (en) 2009-05-29
CN1618465A (en) 2005-05-25
TR200200607T2 (en) 2002-06-21
HUP0202804A3 (en) 2004-08-30
EP1410805A1 (en) 2004-04-21
WO2001017551A3 (en) 2001-09-27
PL354039A1 (en) 2003-12-15
DE60027029D1 (en) 2006-05-18
CY1107457T1 (en) 2012-12-19
HU0303215D0 (en) 2003-11-28
NZ517621A (en) 2003-09-26
ZA200201810B (en) 2004-05-26
PL201264B1 (en) 2009-03-31
MXPA02002484A (en) 2002-08-28
CZ2002843A3 (en) 2002-08-14
PT1210113E (en) 2006-07-31
US7101560B2 (en) 2006-09-05
SI1410805T1 (en) 2006-04-30
HUP0202804A2 (en) 2002-12-28
HK1048435A1 (en) 2003-04-04
EP1210113B1 (en) 2006-03-29
KR100594668B1 (en) 2006-06-30
IL158107A0 (en) 2004-03-28
CA2384064C (en) 2010-06-01
NO20021116D0 (en) 2002-03-06
DE60024893T2 (en) 2006-07-06
SI1210113T1 (en) 2006-08-31
DE60024893D1 (en) 2006-01-19
DK1410805T3 (en) 2006-04-18
NO20033715D0 (en) 2003-08-21
WO2001017551A2 (en) 2001-03-15
KR20030087081A (en) 2003-11-12
ES2261243T3 (en) 2006-11-16
NO20033715L (en) 2002-04-30
KR20020027630A (en) 2002-04-13
ATE321569T1 (en) 2006-04-15
US6936255B1 (en) 2005-08-30
CN1387443A (en) 2002-12-25
NO20021116L (en) 2002-04-30
HUP0303215A3 (en) 2008-04-28
ZA200306402B (en) 2004-08-02
BR0014171A (en) 2002-05-21
TW200408405A (en) 2004-06-01
HU228687B1 (en) 2013-05-28
CN100389824C (en) 2008-05-28
ES2253636T3 (en) 2006-06-01
CA2443214C (en) 2006-03-21
CN1325117C (en) 2007-07-11
CY1106090T1 (en) 2011-06-08
CA2384064A1 (en) 2001-03-15
IL148456A0 (en) 2002-09-12
GC0000201A (en) 2006-03-29
ATE312624T1 (en) 2005-12-15
NO332800B1 (en) 2013-01-14
CA2443214A1 (en) 2001-03-15
EP1769806A3 (en) 2007-10-24
EP1769806A2 (en) 2007-04-04
HK1048435B (en) 2007-01-05
MY142842A (en) 2011-01-14
NO2012016I1 (en) 2012-10-15
US20040126394A1 (en) 2004-07-01
HK1064958A1 (en) 2005-02-08
NZ527560A (en) 2004-12-24
US20060280756A1 (en) 2006-12-14
JP2003508495A (en) 2003-03-04
EP1410805B1 (en) 2005-12-14
AU7775100A (en) 2001-04-10
AU766494B2 (en) 2003-10-16
DE60027029T2 (en) 2006-10-19
NO2012016I2 (en) 2012-10-08

Similar Documents

Publication Publication Date Title
GB9921146D0 (en) Novel composition
HUP0202826A3 (en) Novel composition
GB9902520D0 (en) Composition
GB9919683D0 (en) Composition
AP2001002273A0 (en) Rescorcinol composition
GB9925709D0 (en) Composition
GB2366984B (en) Composition
GB9920148D0 (en) Novel composition
GB9914446D0 (en) Composition
GB2357714B (en) Composition
GB9914582D0 (en) Composition
GB9911933D0 (en) Composition
GB9926931D0 (en) Novel composition
GB9907909D0 (en) Novel composition
GB9922544D0 (en) Novel composition
GB9930569D0 (en) Novel composition
GB9914487D0 (en) Novel composition
GB9928693D0 (en) Novel composition
GB9919955D0 (en) Composition
GB9916231D0 (en) Composition
GB9916226D0 (en) Composition
GB9916225D0 (en) Composition
GB9916197D0 (en) Composition
GB9916194D0 (en) Composition
GB9915435D0 (en) Composition