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ZA200204268B - Gastroretentive controlled release pharmaceutical dosage forms. - Google Patents

Gastroretentive controlled release pharmaceutical dosage forms.

Info

Publication number
ZA200204268B
ZA200204268B ZA200204268A ZA200204268A ZA200204268B ZA 200204268 B ZA200204268 B ZA 200204268B ZA 200204268 A ZA200204268 A ZA 200204268A ZA 200204268 A ZA200204268 A ZA 200204268A ZA 200204268 B ZA200204268 B ZA 200204268B
Authority
ZA
South Africa
Prior art keywords
polymers
controlled release
dosage forms
pharmaceutical dosage
release pharmaceutical
Prior art date
Application number
ZA200204268A
Other languages
English (en)
Inventor
Michael Friedman
Eran Lavy
Eytan Klausner
Amnon Hoffman
Original Assignee
Yissum Res Dev Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Res Dev Co filed Critical Yissum Res Dev Co
Publication of ZA200204268B publication Critical patent/ZA200204268B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200204268A 1999-11-29 2002-05-28 Gastroretentive controlled release pharmaceutical dosage forms. ZA200204268B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL13319699A IL133196A0 (en) 1999-11-29 1999-11-29 Gastroretentive controlled release pharmaceutical dosage forms

Publications (1)

Publication Number Publication Date
ZA200204268B true ZA200204268B (en) 2003-08-28

Family

ID=11073546

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200204268A ZA200204268B (en) 1999-11-29 2002-05-28 Gastroretentive controlled release pharmaceutical dosage forms.

Country Status (12)

Country Link
US (1) US6685962B2 (xx)
EP (1) EP1235557B1 (xx)
JP (1) JP4679020B2 (xx)
AT (1) ATE300286T1 (xx)
AU (1) AU783062B2 (xx)
CA (1) CA2392361C (xx)
DE (1) DE60021604T2 (xx)
ES (1) ES2243327T3 (xx)
IL (2) IL133196A0 (xx)
RU (1) RU2002114348A (xx)
WO (1) WO2001037812A2 (xx)
ZA (1) ZA200204268B (xx)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040219186A1 (en) * 2001-08-16 2004-11-04 Ayres James W. Expandable gastric retention device
TWI312285B (en) * 2001-10-25 2009-07-21 Depomed Inc Methods of treatment using a gastric retained gabapentin dosage
AUPR951501A0 (en) * 2001-12-14 2002-01-24 Smart Drug Systems Inc Modified sustained release pharmaceutical system
WO2004056343A1 (en) 2002-12-19 2004-07-08 Polymorfix, Inc. Ingestible formulations for transient, noninvasive reduction of gastric volume
US7554452B2 (en) * 2003-07-18 2009-06-30 Cary Cole Ingestible tracking and locating device
CA2542512A1 (en) * 2003-09-04 2005-03-17 Nathan Ravi Hydrogel nanocompsites for ophthalmic applications
WO2005030179A1 (en) * 2003-09-29 2005-04-07 Cj Corporation Sustained-release formulations
AU2004296404A1 (en) * 2003-12-09 2005-06-23 Spherics, Inc. Bioadhesive polymers with catechol functionality
US20080089933A1 (en) * 2006-10-16 2008-04-17 Amir Alon Device and method for reducing calorie intake
US20050196355A1 (en) * 2004-03-03 2005-09-08 Constantine Georgiades Film products having controlled disintegration properties
US8007827B2 (en) * 2004-04-02 2011-08-30 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties
EP1750862B1 (en) * 2004-06-04 2011-01-05 Teva Pharmaceutical Industries Ltd. Pharmaceutical composition containing irbesartan
US20080311191A1 (en) * 2004-08-27 2008-12-18 Avinash Nangia Multi-Layer Tablets and Bioadhesive Dosage Forms
KR100866720B1 (ko) * 2004-12-27 2008-11-05 에자이 알앤드디 매니지먼트 가부시키가이샤 항치매 약물의 안정화 방법
US20070129402A1 (en) * 2004-12-27 2007-06-07 Eisai Research Institute Sustained release formulations
US20060246003A1 (en) * 2004-12-27 2006-11-02 Eisai Co. Ltd. Composition containing anti-dementia drug
US20060280789A1 (en) * 2004-12-27 2006-12-14 Eisai Research Institute Sustained release formulations
IL166183A0 (en) * 2005-01-06 2006-01-15 Yissum Res Dev Co Novel diagnostic and imaging techniques of the gi tract
KR100822519B1 (ko) * 2005-02-15 2008-04-16 주식회사종근당 위장 내에서 제어방출되는 단일 매트릭스 정제
EP1933811A2 (en) * 2005-09-30 2008-06-25 Alza Corporation Banded controlled release nanoparticle active agent formulation dosage forms and methods
US20070092565A1 (en) * 2005-10-25 2007-04-26 Pharmascience Inc. Gastric retention drug delivery system
US8298574B2 (en) 2006-01-18 2012-10-30 Intec Pharma Ltd. Method and apparatus for forming delivery devices for oral intake of an agent
CA2642479C (en) * 2006-02-15 2014-08-19 Intec Pharma Ltd. A gastro-retentive system for the delivery of macromolecules
EP2086515A2 (en) * 2006-03-02 2009-08-12 Vaunnex, Inc. Rate-controlled bioadhesive oral dosage formulations
AR062659A1 (es) * 2006-09-08 2008-11-26 Drug Tech Corp Composicion de liberacion sostenida de levodopa y metodo para su uso
SI2124884T1 (sl) 2006-12-22 2019-09-30 Ironwood Pharmaceuticals, Inc. Pripravki, ki obsegajo sekvestrante žolčnih kislin, za zdravljenje motenj požiralnika
WO2008115597A2 (en) * 2007-03-21 2008-09-25 Cytologic, Inc. Cytokine muteins and methods for enhancing immune responses in mammals
US8961412B2 (en) 2007-09-25 2015-02-24 Proteus Digital Health, Inc. In-body device with virtual dipole signal amplification
US20090253808A1 (en) 2007-11-12 2009-10-08 Pharmaceutics International, Inc. Tri-molecular complexes and their use in drug delivery systems
ES2606395T3 (es) 2008-04-18 2017-03-23 Intec Pharma Ltd. Administración de fármacos gastrorretentivos para carbidopa/levodopa
WO2009136493A1 (ja) * 2008-05-08 2009-11-12 パナソニック株式会社 不揮発性記憶素子、及び、不揮発性記憶素子又は不揮発性記憶装置の製造方法
US8287902B2 (en) * 2008-07-23 2012-10-16 Rainbow Medical Ltd. Enhanced-diffusion capsule
PL2378883T3 (pl) * 2008-12-04 2016-06-30 Intec Pharma Ltd SYSTEM DOSTARCZANIA LEKU ZATRZYMYWANEGO W ŻOŁĄDKU dLA ZALEPLONU
BRPI1013856A2 (pt) 2009-04-20 2016-04-05 Elcelyx Therapeutics Inc terapias à base de ligantes de receptores quimiossensíveis
US9901551B2 (en) 2009-04-20 2018-02-27 Ambra Bioscience Llc Chemosensory receptor ligand-based therapies
US8828953B2 (en) * 2009-04-20 2014-09-09 NaZura BioHealth, Inc. Chemosensory receptor ligand-based therapies
US20100286628A1 (en) * 2009-05-07 2010-11-11 Rainbow Medical Ltd Gastric anchor
US8414559B2 (en) * 2009-05-07 2013-04-09 Rainbow Medical Ltd. Gastroretentive duodenal pill
US20110066175A1 (en) * 2009-05-07 2011-03-17 Rainbow Medical Ltd. Gastric anchor
US20120321706A1 (en) * 2009-10-19 2012-12-20 Intec Pharma Ltd. Novel gastroretentive dosage forms of poorly soluble drugs
CN106913902A (zh) 2009-11-09 2017-07-04 聚光灯技术合伙有限责任公司 多糖基水凝胶
EP2498764B1 (en) 2009-11-09 2017-09-06 Spotlight Technology Partners LLC Fragmented hydrogels
US20110153027A1 (en) * 2009-12-18 2011-06-23 Vysera Biomedical Limited Drug Delivery System
US8772429B2 (en) 2009-12-18 2014-07-08 Vysera Biomedical Limited Biomaterial
EP2544666A2 (en) 2010-03-09 2013-01-16 Council of Scientific and Industrial Research Gastroretentive, extended release composition of therapeutic agent
US8628554B2 (en) 2010-06-13 2014-01-14 Virender K. Sharma Intragastric device for treating obesity
US10010439B2 (en) 2010-06-13 2018-07-03 Synerz Medical, Inc. Intragastric device for treating obesity
US10420665B2 (en) 2010-06-13 2019-09-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
US9486463B2 (en) 2010-10-19 2016-11-08 Ambra Bioscience Llc Chemosensory receptor ligand-based therapies
AU2012204162B2 (en) 2011-01-07 2017-04-20 Anji Pharmaceuticals Inc. Chemosensory receptor ligand-based therapies
US8722066B2 (en) 2011-03-29 2014-05-13 Primigenia, LLC Devices and methods for weight control and weight loss
US20130143867A1 (en) 2011-12-02 2013-06-06 Sychroneuron Inc. Acamprosate formulations, methods of using the same, and combinations comprising the same
WO2013158928A2 (en) 2012-04-18 2013-10-24 Elcelyx Therapeutics, Inc. Chemosensory receptor ligand-based therapies
WO2014039951A1 (en) 2012-09-10 2014-03-13 Novartis Ag Enteral pharmaceutical compositions
US9682081B2 (en) 2013-04-25 2017-06-20 Sun Pharmaceutical Industries Limited Pharmaceutical gastro-retentive solid oral dosage form of nilotinib
CN105431144A (zh) 2013-06-05 2016-03-23 思康脑侒股份有限公司 阿坎酸制剂、使用阿坎酸制剂的方法以及包含阿坎酸制剂的组合
CN105828809B (zh) * 2013-12-20 2019-10-29 费森尤斯卡比德国有限公司 包含脂质和活性药剂的具有聚合物涂层的微胶囊
CN106535878B (zh) 2014-06-02 2022-11-01 科莱西奥生物科技有限公司 可张开的胃内滞留剂型
JP6666858B2 (ja) 2014-06-11 2020-03-18 マサチューセッツ インスティテュート オブ テクノロジー 滞留構造体および関連方法
US20170266112A1 (en) 2014-06-11 2017-09-21 Massachusetts Institute Of Technology Residence structures and related methods
US9492396B2 (en) 2014-07-15 2016-11-15 Yossi Gross Enhanced drug delivery pill
CN106236715B (zh) * 2015-06-03 2021-05-07 南京三迭纪医药科技有限公司 药品剂型及其使用
EP3302442B1 (en) 2015-06-03 2024-10-16 Triastek, Inc. Dosage forms and use thereof
JP2018517735A (ja) 2015-06-17 2018-07-05 バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． フマル酸ジメチル粒子及びそれらの医薬組成物
CN118975972A (zh) 2015-10-23 2024-11-19 林德拉治疗公司 用于治疗剂缓释的胃驻留系统及其使用方法
WO2017075096A1 (en) * 2015-10-26 2017-05-04 Blaesi Aron H Solid dosage form immediate drug release and apparatus and method for manufacture thereof
US11478427B2 (en) * 2015-10-26 2022-10-25 Aron H. Blaesi Dosage form comprising structural framework of two-dimensional elements
US11129798B2 (en) 2016-08-19 2021-09-28 Aron H. Blaesi Fibrous dosage form
EP3383365A1 (en) * 2015-12-01 2018-10-10 Clexio Biosciences Ltd. Gastric retentive devices
JP2018537201A (ja) * 2015-12-02 2018-12-20 クレキシオ バイオサイエンシーズ エルティーディー． 胃保持型投与形態を調整する装置および方法
BR112018011636B1 (pt) 2015-12-08 2024-03-12 Lyndra Therapeutics, Inc Sistema de residência gástrico para liberação sustentada de um agente terapêutico
US11173135B2 (en) 2016-03-17 2021-11-16 Thiogenesis Therapeutics, Inc. Compositions for controlled release of cysteamine and systemic treatment of cysteamine sensitive disorders
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity
CN119925721A (zh) 2016-05-27 2025-05-06 林德拉治疗公司 用于胃驻留系统的材料结构
EP3481371A1 (en) * 2016-07-11 2019-05-15 Intec Pharma Ltd. Oral gastroretentive formulations and uses thereof
CN110022861B (zh) 2016-09-30 2024-06-28 林德拉治疗公司 用于金刚烷类药物缓释的胃驻留系统
IL266377B2 (en) 2016-12-02 2023-10-01 Clexio Biosciences Ltd Gastric residence system
US12102721B2 (en) 2017-01-26 2024-10-01 Triastek, Inc. Dosage forms of controlled release at specific gastrointestinal sites
AU2018279853B2 (en) 2017-06-09 2024-07-04 Lyndra Therapeutics, Inc. Gastric residence systems with release rate-modulating films
CN118924717A (zh) 2017-09-20 2024-11-12 硫创治疗公司 用于治疗半胱胺敏感性病症的方法
WO2019111132A1 (en) 2017-12-04 2019-06-13 Clexio Biosciences Ltd. Long acting gastric residence system
CN116270513A (zh) 2018-01-09 2023-06-23 南京三迭纪医药科技有限公司 一种包含固定剂量adhd非兴奋剂和adhd兴奋剂的复方口服药物剂型
CN114191307A (zh) 2020-09-17 2022-03-18 上海汉都医药科技有限公司 一种口腔滞留装置及其制备方法
US11911513B2 (en) 2018-05-23 2024-02-27 Shanghai Wd Pharmaceutical Co., Ltd Controlled-release system of active pharmaceutical ingredient and preparation method therefor
EP3797818B1 (en) 2018-05-23 2023-01-18 Shanghai WD Pharmaceutical Co., Ltd Controlled-release system of active pharmaceutical ingredient and preparation method therefor
US10675248B2 (en) 2018-08-14 2020-06-09 Alma Therapeutics Ltd. Expandable pill
CA3201057A1 (en) 2020-12-08 2022-06-16 Mark Christopher LAY Improvements to devices and methods for delivery of substances to animals
EP4340814A4 (en) 2021-05-20 2025-04-02 E Ink Corporation Care product dispensing system with electroplating

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3574820A (en) 1968-01-08 1971-04-13 Upjohn Co Medicinal dosage forms of unpolymerized thiolated gelatin with a cross-linking accelerating agent providing slowly released medication from a swollen matrix
US4207890A (en) 1977-01-04 1980-06-17 Mcneilab, Inc. Drug-dispensing device and method
US4434153A (en) 1982-03-22 1984-02-28 Alza Corporation Drug delivery system comprising a reservoir containing a plurality of tiny pills
US4735804A (en) 1985-05-10 1988-04-05 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
US4767627A (en) 1985-05-29 1988-08-30 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
US4758436A (en) 1985-05-29 1988-07-19 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
US5002772A (en) 1988-05-31 1991-03-26 Pfizer Inc. Gastric retention system for controlled drug release
US5217712A (en) 1989-09-20 1993-06-08 Merck & Co., Inc. Bioerodible thermoset elastomers
US5047464A (en) 1989-09-20 1991-09-10 Merck & Co., Inc. Bioerodible thermoset elastomers
IT1265240B1 (it) * 1993-11-30 1996-10-31 Ekita Investments Nv Compressa farmaceutica a rilascio controllato, di forma lenticolare
DE4406424A1 (de) 1994-02-28 1995-08-31 Bayer Ag Expandierbare Arzneiformen
US5840332A (en) * 1996-01-18 1998-11-24 Perio Products Ltd. Gastrointestinal drug delivery system

Also Published As

Publication number Publication date
ATE300286T1 (de) 2005-08-15
JP4679020B2 (ja) 2011-04-27
JP2003514845A (ja) 2003-04-22
CA2392361A1 (en) 2001-05-31
WO2001037812A2 (en) 2001-05-31
ES2243327T3 (es) 2005-12-01
WO2001037812A3 (en) 2002-02-21
IL149853A (en) 2006-12-31
US20030021845A1 (en) 2003-01-30
AU783062B2 (en) 2005-09-22
DE60021604D1 (de) 2005-09-01
AU1647701A (en) 2001-06-04
CA2392361C (en) 2010-01-19
IL133196A0 (en) 2001-03-19
EP1235557A2 (en) 2002-09-04
RU2002114348A (ru) 2004-01-10
US6685962B2 (en) 2004-02-03
EP1235557B1 (en) 2005-07-27
DE60021604T2 (de) 2006-06-01

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