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YU32003A - Novi kristalni i solvatni oblici ondansteron hlorovodonika i postupci za njihovo pripremanje - Google Patents

Novi kristalni i solvatni oblici ondansteron hlorovodonika i postupci za njihovo pripremanje

Info

Publication number
YU32003A
YU32003A YU32003A YUP32003A YU32003A YU 32003 A YU32003 A YU 32003A YU 32003 A YU32003 A YU 32003A YU P32003 A YUP32003 A YU P32003A YU 32003 A YU32003 A YU 32003A
Authority
YU
Yugoslavia
Prior art keywords
processes
ondansteron
hydrochloride
preparation
novel crystal
Prior art date
Application number
YU32003A
Other languages
English (en)
Inventor
Ramy Lidor-Hadas
Judith Aronhime
Revital Lifshitz
Shlomit Weizel
Valerie Niddam
Asher Maymon
Original Assignee
Teva Pharmaceutical Industries Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharmaceutical Industries Ltd. filed Critical Teva Pharmaceutical Industries Ltd.
Publication of YU32003A publication Critical patent/YU32003A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Predmet pronalaska obezbedjune nove kristalne, polimorfne i solvate oblike ondansteron hlorovodonika. Takodje su obezbedjeni postupci za primanje i medjusobno pretvaranje polimorfnih oblika. Dalje su obezbedjeni farmaceutski preparati i terapeutski postupci za upotrebu novih polimorfnih oblika i hidrata.[The present invention provides novel ondansetron hydrochloride crystalline polymorphic forms and solvates. Processes for making and interconverting the polymorphic forms are also provided. Further provided are pharmaceutical compositions and therapeutic methods using the novel polymorphic forms and hydrates.
YU32003A 2000-10-30 2001-10-30 Novi kristalni i solvatni oblici ondansteron hlorovodonika i postupci za njihovo pripremanje YU32003A (sh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24428300P 2000-10-30 2000-10-30
US25381900P 2000-11-29 2000-11-29
US26553901P 2001-01-31 2001-01-31

Publications (1)

Publication Number Publication Date
YU32003A true YU32003A (sh) 2006-05-25

Family

ID=27399743

Family Applications (1)

Application Number Title Priority Date Filing Date
YU32003A YU32003A (sh) 2000-10-30 2001-10-30 Novi kristalni i solvatni oblici ondansteron hlorovodonika i postupci za njihovo pripremanje

Country Status (20)

Country Link
US (1) US20020107275A1 (sh)
EP (1) EP1339707A2 (sh)
JP (1) JP2004525083A (sh)
KR (1) KR20030042038A (sh)
CN (1) CN1498216A (sh)
AU (1) AU2002230935A1 (sh)
CA (1) CA2426026A1 (sh)
CZ (1) CZ20031397A3 (sh)
DE (1) DE01991193T1 (sh)
ES (1) ES2204358T1 (sh)
HR (1) HRP20030432A2 (sh)
HU (1) HUP0401239A2 (sh)
IL (1) IL155644A0 (sh)
IS (1) IS6797A (sh)
MX (1) MXPA03003761A (sh)
NO (1) NO20031928L (sh)
PL (1) PL366150A1 (sh)
SK (1) SK6182003A3 (sh)
WO (1) WO2002036558A2 (sh)
YU (1) YU32003A (sh)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL368837A1 (en) * 2001-01-11 2005-04-04 Teva Pharmaceutical Industries Ltd. An improved process for preparing pure ondansetron hydrochloride dihydrate
PL373191A1 (en) 2002-04-29 2005-08-22 Teva Gyogyszergyar Reszvenytarsasag Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1h-imidazol-1-yl)methyl]-4h-carbazol-4-one
FI6164U1 (fi) * 2003-01-09 2004-03-15 Synthon Bv Ondansetronmuotoja
EP1828141A4 (en) * 2004-10-26 2009-04-01 Ipca Lab Ltd STAINING METHOD FOR PREPARING THE ANTIEMETIC 1,2,3,9-TETRAHYDRO-9-METHYL-3 - [(2-METHYL) -1H-IMIDAZOLE-1-YL) METHYL] -4H-CARBAZOLE-4-ON
KR20140088230A (ko) * 2006-01-27 2014-07-09 앱탈리스 파마테크, 인코포레이티드 약 염기성 약물과 유기산을 포함하는 약물 전달 시스템
AU2007211091B8 (en) * 2006-01-27 2013-08-29 Adare Pharmaceuticals, Inc. Drug delivery systems comprising weakly basic selective serotonin 5-HT3 blocking agent and organic acids
US20100105724A1 (en) * 2006-12-07 2010-04-29 Helsinn Healthcare Sa Crystalline and amorphous forms of palonosetron hydrochloride
US8133506B2 (en) 2008-03-12 2012-03-13 Aptalis Pharmatech, Inc. Drug delivery systems comprising weakly basic drugs and organic acids
CN102190594A (zh) * 2010-03-17 2011-09-21 上海医药工业研究院 阿戈美拉汀氯化氢水合物及其制备方法
CN102190595A (zh) * 2010-03-17 2011-09-21 上海医药工业研究院 阿戈美拉汀溴化氢水合物及其制备方法
AU2014348523B2 (en) 2013-11-15 2019-01-03 Akebia Therapeutics, Inc. Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4695578A (en) * 1984-01-25 1987-09-22 Glaxo Group Limited 1,2,3,9-tetrahydro-3-imidazol-1-ylmethyl-4H-carbazol-4-ones, composition containing them, and method of using them to treat neuronal 5HT function disturbances
EP0385517B1 (en) * 1985-03-14 1993-04-14 BEECHAM GROUP plc Medicaments for the treatment of emesis
GB8518741D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Process
GB8518742D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Process
GB8630071D0 (en) * 1986-12-17 1987-01-28 Glaxo Group Ltd Medicaments
GB8816187D0 (en) * 1988-07-07 1988-08-10 Glaxo Group Ltd Medicaments
US5344658A (en) * 1989-06-28 1994-09-06 Glaxo Group Limited Process and composition using ondansetron
AU2295792A (en) * 1991-06-26 1993-01-25 Sepracor, Inc. Method and compositions for treating emesis, nausea and other disorders using optically pure r(+) ondansetron
CA2106642C (en) * 1992-10-14 2005-08-16 Peter Bod Carbazolone derivatives and process for preparing the same
GB9423588D0 (en) * 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
GB9423511D0 (en) * 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
CN1045437C (zh) * 1994-12-29 1999-10-06 中国科学院上海有机化学研究所 恩丹西酮及其生理盐的合成
EP1207160A1 (en) * 2000-11-20 2002-05-22 Hanmi Pharm. Co., Ltd. Process for the preparation of 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)-methyl)-4H-carbazol-4-one
PL373191A1 (en) * 2002-04-29 2005-08-22 Teva Gyogyszergyar Reszvenytarsasag Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1h-imidazol-1-yl)methyl]-4h-carbazol-4-one
CN1665803A (zh) * 2002-04-30 2005-09-07 特瓦药厂有限公司 新晶形的昂丹司琼及其制备方法、含有该新晶形的药物组合物以及用其治疗恶心的方法

Also Published As

Publication number Publication date
CA2426026A1 (en) 2002-05-10
CN1498216A (zh) 2004-05-19
KR20030042038A (ko) 2003-05-27
IL155644A0 (en) 2003-11-23
AU2002230935A1 (en) 2002-05-15
CZ20031397A3 (cs) 2003-11-12
HRP20030432A2 (en) 2004-06-30
HUP0401239A2 (hu) 2004-12-28
WO2002036558A3 (en) 2003-02-06
PL366150A1 (en) 2005-01-24
MXPA03003761A (es) 2003-07-28
US20020107275A1 (en) 2002-08-08
NO20031928L (no) 2003-06-27
NO20031928D0 (no) 2003-04-29
IS6797A (is) 2003-04-29
WO2002036558A2 (en) 2002-05-10
ES2204358T1 (es) 2004-05-01
JP2004525083A (ja) 2004-08-19
SK6182003A3 (en) 2004-03-02
EP1339707A2 (en) 2003-09-03
DE01991193T1 (de) 2004-07-08

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