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WO2025210149A1 - Composition fongicide - Google Patents

Composition fongicide

Info

Publication number
WO2025210149A1
WO2025210149A1 PCT/EP2025/059131 EP2025059131W WO2025210149A1 WO 2025210149 A1 WO2025210149 A1 WO 2025210149A1 EP 2025059131 W EP2025059131 W EP 2025059131W WO 2025210149 A1 WO2025210149 A1 WO 2025210149A1
Authority
WO
WIPO (PCT)
Prior art keywords
component
composition
compound
streptomyces
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/EP2025/059131
Other languages
English (en)
Inventor
Stephane BIERI
Dimitrios DRAKOPOULOS
Renu KAPIL
Santiago VALDES
George STAVRIDES
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Crop Protection AG Switzerland
Original Assignee
Syngenta Crop Protection AG Switzerland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Crop Protection AG Switzerland filed Critical Syngenta Crop Protection AG Switzerland
Publication of WO2025210149A1 publication Critical patent/WO2025210149A1/fr
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/20—Bacteria; Substances produced thereby or obtained therefrom
    • A01N63/28—Streptomyces
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/713—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with four or more nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P3/00—Fungicides

Definitions

  • Cyclothiazomycin C is a known compound. The structure of cyclothazomycin C is disclosed on p.
  • Streptimidone is a known compound of Formula III
  • component (A) comprises a composition comprising a Streptomyces chrestomyceticus and a metabolite disclosed herein, preferably a metabolite which can be produced by the Streptomyces chrestomyceticus.
  • compositions as disclosed herein comprising a component (B) which comprises a compound selected from the group consisting of acibenzolar-S-methyl, azoxystrobin, benzovindiflupyr, bromuconazole, chlorothalonil, cyprodinil, difenoconazole, fenpicoxamid, fenpropidin, florylpicoxamid, folpet, isoflucypram, mefentrifluconazole, metyltetraprole, proquinazid, prothioconazole, pydiflumetofen, pyraclostrobin and spiroxamine resulted in a surprising synergistic activity against phytopathogenic fungi.
  • component (B) which comprises a compound selected from the group consisting of acibenzolar-S-methyl, azoxystrobin, benzovindiflupyr, bromuconazole, chlorothalonil, cyprodinil, difenoconazo
  • a composition comprising components (A) and (B) as active ingredients according to the present invention showed synergistic activity against phytopathogenic microorganisms, such as phytopathogenic fungi, such as Zymoseptoria (syn. Septoria) tritici and Puccinia recondita f. sp. tritici (Puccinia triticina) and Pyricularia oryzae.
  • phytopathogenic fungi such as Zymoseptoria (syn. Septoria) tritici and Puccinia recondita f. sp. tritici (Puccinia triticina) and Pyricularia oryzae.
  • Zymoseptoria tritici and Puccinia recondita f. sp. tritici were affected by a composition according to the present invention on wheat.
  • Pyricularia oryzae was affected by a composition according to the present invention on rice.
  • a composition of the present invention comprises a component (A) and component (B) at a weight ratio of component (A) to component (B) of from 400:1 to 1 :150, for instance from 300:1 to 1 :100, for instance a weight ratio of component (A) to component (B) of from 250:1 to 1 :50, for instance a weight ratio of component (A) to component (B) of from 200:1 to 1 :25, for instance a weight ratio of component (A) to component (B) of from 100:1 to 1 :10, for instance a weight ratio of component (A) to component (B) of from 90:1 to 1 :9, for instance a weight ratio of component A to component B of from 80:1 to 1 :8, for instance a weight ratio of component (A) to component (B) of from 70:1 to 1 :7, for instance a weight ratio of component (A) to component (B)
  • a composition comprising components (A) and (B) as active ingredients, is a composition wherein component (A) comprises a Streptomyces chrestomyceticusas disclosed herein above, and wherein component (B) comprises prothioconazole at a weight ratio of 100:1 to 1 :50, preferably at a weight ratio of 80:1 to 1 :20, preferably at a weight ratio of 40:1 to 1 : 10.
  • a composition according to this embodiment was surprisingly effective against phytopathogenic fungi, such as Zymoseptoria tritici and Puccinia recondita f. sp. tritici.
  • a composition comprising components (A) and (B) as active ingredients, is a composition wherein component (A) comprises a Streptomyces chrestomyceticus as disclosed herein above, and wherein component (B) comprises difenoconazole at a weight ration of 200:1 to 1 :20, preferably a weight ratio of 150:1 to 1 : 10.
  • a composition according to this embodiment was surprisingly effective against phytopathogenic fungi, such as Zymoseptoria tritici, Puccinia recondita f. sp. tritici, and Pyricularia oryzae.
  • a composition comprising components (A) and (B) as active ingredients, is a composition wherein component (A) comprises a Streptomyces chrestomyceticus as disclosed herein above, and wherein component (B) comprises bromuconazole at a weight ration of 20:1 to 1 :20, preferably a weight ratio of 10:1 to 1 : 10, preferably a weight ratio of 5:1 to 1 :5.
  • a composition according to this embodiment was surprisingly effective against surprisingly effective against phytopathogenic fungi, such as Pyricularia oryzae, Zymoseptoria tritici, Puccinia recondita f. sp. tritici, preferably against Zymoseptoria tritici.
  • a composition comprising components (A) and (B) as active ingredients, may be a composition wherein component (A) comprises a Streptomyces chrestomyceticus as disclosed herein above, and wherein component (B) comprises fenpropidin at a weight ratio of 50:1 to 1 :50, preferably a weight ratio of 20:1 to 1 : 30, preferably a weight ration of 15:1 to 1 : 20.
  • a composition according to this embodiment was surprisingly effective against phytopathogenic fungi, such as Zymoseptoria tritici and Puccinia recondita f. sp. tritici.
  • a composition comprising components (A) and (B) as active ingredients, may be a composition wherein component (A) comprises a Streptomyces chrestomyceticus as disclosed herein above, and wherein component (B) comprises spiroxamine at a weight ratio of 50:1 to 1 :50, preferably a weight ratio of 30:1 to 1 : 30, preferably a weight ratio of 20:1 to 1 : 20.
  • a composition according to this embodiment was surprisingly effective against phytopathogenic fungi, such as Zymoseptoria tritici and Puccinia recondita f. sp. tritici.
  • a composition comprising components (A) and (B) as active ingredients, may be a composition wherein component (A) comprises a Streptomyces chrestomyceticus as disclosed herein above, and wherein component (B) comprises pydiflumetofen at a weight ratio of 150:1 to 1 :50, preferably a weight ratio of 100:1 to 1 : 30, preferably a weight ratio of 90:1 to 1 : 20.
  • a composition according to this embodiment was surprisingly effective against phytopathogenic fungi, such as Zymoseptoria tritici and Puccinia recondita f. sp. tritici.
  • a composition comprising components (A) and (B) as active ingredients, may be a composition wherein component (A) comprises a Streptomyces chrestomyceticus as disclosed herein above, and wherein component (B) comprises benzovindiflupyr at a weight ratio of 250:1 to 1 :20, preferably a weight ratio of 200:1 to 1 : 10, preferably a weight ratio of 180:1 to 1 :5.
  • a composition according to this embodiment was surprisingly effective against phytopathogenic fungi, such as Zymoseptoria tritici and Puccinia recondita f. sp. tritici and Pyricularia oryzae.
  • a composition comprising components (A) and (B) as active ingredients, may be a composition wherein component (A) comprises a Streptomyces chrestomyceticus as disclosed herein above, and wherein component (B) comprises isoflucypram at a weight ratio of 350:1 to 1 :20, preferably a weight ratio of 300:1 to 1 : 10, preferably a weight ratio of 280:1 to 1 : 5.
  • a composition according to this embodiment was surprisingly effective against Zymoseptoria tritici and Puccinia recondita f. sp. tritici, preferably against phytopathogenic fungi, such as Puccinia recondita f. sp. tritici.
  • a composition comprising components (A) and (B) as active ingredients, may be a composition wherein component (A) comprises a Streptomyces chrestomyceticus as disclosed herein above, and wherein component (B) comprises cyprodinil at a weight ratio of 50:1 to 1 :50, preferably a weight ratio of 40:1 to 1 : 40, preferably a weight ratio of 30:1 to 1 : 30, preferably a weight ratio of 20:1 to 1 :20, preferably a weight ratio of 10:1 to 1 :10.
  • a composition according to this embodiment was surprisingly effective against phytopathogenic fungi, such as Zymoseptoria tritici and Puccinia recondita f. sp. tritici.
  • a composition comprising components (A) and (B) as active ingredients, may be a composition wherein component (A) comprises a Streptomyces chrestomyceticus as disclosed herein above, and wherein component (B) comprises azoxystrobin at a weight ratio of 100:1 to 1 :20, preferably a weight ratio of 80:1 to 1 :10.
  • a composition according to this embodiment was surprisingly effective against phytopathogenic fungi, such as Zymoseptoria tritici, Puccinia recondita f. sp. tritici and Pyricularia oryzae.
  • a composition comprising components (A) and (B) as active ingredients, may be a composition wherein component (A) comprises a Streptomyces chrestomyceticus as disclosed herein above, and wherein component (B) comprises pyraclostrobin at a weight ratio of 100:1 to 1 :20, preferably a weight ratio of 80:1 to 1 : 10.
  • a composition according to this embodiment was surprisingly effective against phytopathogenic fungi, such as Zymoseptoria tritici and Puccinia recondita f. sp. tritici.
  • a composition comprising components (A) and (B) as active ingredients, may be a composition wherein component (A) comprises a Streptomyces chrestomyceticus as disclosed herein above, and wherein component (B) comprises metyltetrapole at a weight ratio of 200:1 to 1 :20, preferably a weight ratio of 150:1 to 1 : 10, preferably a weight ratio of 100:1 to 1 :5 .
  • a composition according to this embodiment was surprisingly effective against phytopathogenic fungi, such as Zymoseptoria tritici and Puccinia recondita f. sp. tritici.
  • a composition comprising components (A) and (B) as active ingredients, may be a composition wherein component (A) comprises a Streptomyces chrestomyceticus as disclosed herein above, and wherein component (B) comprises proquinazid at a weight ratio of 150:1 to 1 :20, preferably a weight ratio of 100:1 to 1 : 10.
  • a composition according to this embodiment was surprisingly effective against phytopathogenic fungi, such as Zymoseptoria tritici and Puccinia recondita f. sp. tritici.
  • a composition comprising components (A) and (B) as active ingredients, may be a composition wherein component (A) comprises a Streptomyces chrestomyceticus as disclosed herein above, and wherein component (B) comprises florylpicoxamid at a weight ratio of 150:1 to 1 :20, preferably a weight ratio of 100:1 to 1 : 10.
  • a composition according to this embodiment was surprisingly effective against phytopathogenic fungi, such as Puccinia recondita f. sp. tritici.
  • a composition comprising components (A) and (B) as active ingredients, may be a composition wherein component (A) comprises a Streptomyces chrestomyceticus as disclosed herein above, and wherein component (B) comprises fenpicoxamid at a weight ratio of 150:1 to 1 :20, preferably a weight ratio of 100:1 to 1 : 10.
  • a composition according to this embodiment was surprisingly effective against phytopathogenic fungi, such as Zymoseptoria tritici and Puccinia recondita f. sp. tritici.
  • a composition comprising components (A) and (B) as active ingredients, may be a composition wherein component (A) comprises a Streptomyces chrestomyceticus as disclosed herein above, and wherein component (B) comprises folpet at a weight ratio of 50:1 to 1 :50, preferably a weight ratio of 40:1 to 1 : 40, preferably a weight ratio of 30:1 to 1 : 30, preferably a weight ratio of 20:1 to 1 :20, preferably a weight ratio of 10:1 to 1 :10.
  • a composition according to this embodiment was surprisingly effective against phytopathogenic fungi, such as Zymoseptoria tritici and Puccinia recondita f. sp. tritici.
  • a composition comprising components (A) and (B) as active ingredients, may be a composition wherein component (A) comprises a Streptomyces chrestomyceticus as disclosed herein above, and wherein component (B) comprises chlorothalonil at a weight ratio of 50:1 to 1 :100, preferably a weight ratio of 20:1 to 1 :50, preferably a weight ratio of 10:1 to 1 :30.
  • a composition according to this embodiment was surprisingly effective against Zymoseptoria tritici and Puccinia recondita f. sp. tritici.
  • a composition according to this embodiment was surprisingly effective against Zymoseptoria tritici and Puccinia recondita f. sp. tritici, and Pyricularia oryzae.
  • a composition comprising components (A) and (B) as active ingredients, is a composition wherein component (A) comprises a Streptomyces chrestomyceticusas disclosed herein and wherein component (B) comprises cyclobutrifluram, for instance at a weight ratio of 10,000:1 to 100:1 , such as 8,000:1 to 200:1 , such as 5,000:1 to 500:1.
  • a composition according to this embodiment was found surprisingly effective against phytopathogenic fungi, such as against and Fusarium graminearum.
  • a composition comprising components (A) and (B) as active ingredients, is a composition wherein component (A) comprises a Streptomyces chrestomyceticus as disclosed herein above, and wherein component (B) comprises metalaxyl, metalaxyl-M, acibenzolar-s-methyl, triticonazole penthiopyrad, sedaxane, thiabendazole, difenoconazole, imidacloprid, thiabendazole, difenoconazole, thiamethoxam, azoxystrobin, pydiflumetofen, fludioxonil, pyraclostrobin, fluoxastrobin, silthiofam, chlorantraniliprole, ethaboxam, ipconazole, prothioconazole, cyantraniliprol, ipconazole, prothioconazole, fluxapyroxad, ox
  • a composition comprising components (A) and (B) as active ingredients, is a composition wherein component (A) comprises a Streptomyces chrestomyceticus as disclosed herein above, and wherein component (B) comprises metalaxyl, metalaxyl-M, acibenzolar-s-methyl, triticonazole, penthiopyrad, sedaxane, thiabendazole, difenoconazole, imidacloprid, thiabendazole, difenoconazole, thiamethoxam, azoxystrobin, pydiflumetofen, fludioxonil, pyraclostrobin, fluoxastrobin, silthiofam, chlorantraniliprole, ethaboxam, ipconazole, prothioconazole, cyantraniliprole, ipconazole, fluxapyroxad, oxathiapiprol
  • the composition according to the present invention further comprises an agriculturally acceptable carrier and, optionally, a surfactant and/or formulation adjuvants.
  • Suitable agricultural adjuvants and/or carriers can be solid or liquid and are substances useful in formulation technology, e.g. natural or regenerated mineral substances, solvents, dispersants, wetting agents, tackifiers, thickeners, binders or fertilizers.
  • Suitable solid carriers include, for example ammonium salts, talc, titanium dioxide, pyrophyllite clay, silica, attapulgite clay, kieselguhr, chalk, diatomaxeous earth, lime, calcium carbonate, bentonite clay, fuller’s earth, cotton seed hulls, wheat flour, soybean flour, pumice, wood flour, walnut shell flour and lignin. Water is generally the carrier of choice for the dilution of concentrates. The amount of carrier may typically range from 0.9% to 99.99% by weight of the composition.
  • compositions according to the present invention may be used in unmodified form or, preferably, together with the adjuvants conventionally employed in the art of formulation. To this end they may be conveniently formulated in known manner to emulsifiable concentrates, coatable pastes, directly sprayable or dilutable solutions or suspensions, dilute emulsions, wettable powders, soluble powders, dusts, granulates, and also encapsulations e.g. in polymeric substances. As with the type of the compositions, the methods of application, such as spraying, atomising, dusting, scattering, coating or pouring, are chosen in accordance with the intended objectives and the prevailing circumstances.
  • the compositions may also contain further adjuvants such as stabilizers, antifoams, viscosity regulators, binders or tackifiers as well as fertilizers, micronutrient donors or other formulations for obtaining special effects.
  • Component (A) as disclosed herein may be a formulation, wherein Streptomyces chrestomyceticus as disclosed herein is formulated as an oil dispersion (OD), a non-aqueous dispersion (NAD) or a flowable formulation.
  • OD oil dispersion
  • NAD non-aqueous dispersion
  • Suitable adjuvants, dispersants, emulsifiers and rheology modifiers in an oil dispersion depend on the type of oil and are known in the art.
  • Suitable emulsifiers can be alcohol ethoxylates/alcoxylates, such as C16/18 ethoxylates, or C16/C18 alcoxylate, or block co-polymers.
  • An adjuvant can be an alkyl polyglucoside.
  • Suitable rheology modifiers can be clay, hydrogenated castor oil and derivatives, fumed silicam polyamides, polyesters or agrilan ODS.
  • Emulsifiable concentrates are homogeneous liquid compositions dispersible in water or other liquid and may consist entirely of an active ingredient a liquid or solid emulsifying agent, or may also contain a liquid carrier, such as xylene, heavy aromatic naphthas, isophorone and other non-volatile organic solvents. In use, these concentrates are dispersed in water or other liquid and normally applied as a spray to the area to be treated. The amount of active ingredient may range from 0.5% to 95% of the concentrate.
  • Granular formulations include both extrudates and relatively coarse particles and are usually applied without dilution to the area in which treatment is required.
  • Typical carriers for granular formulations include sand, fuller’s earth, attapulgite clay, bentonite clays, montmorillonite clay, vermiculite, perlite, calcium carbonate, brick, pumice, pyrophyllite, kaolin, dolomite, plaster, wood flour, ground corn cobs, ground peanut hulls, sugars, sodium chloride, sodium sulphate, sodium silicate, sodium borate, magnesia, mica, iron oxide, zinc oxide, titanium oxide, antimony oxide, cryolite, gypsum, diatomaceous earth, calcium sulphate and other organic or inorganic materials which absorb or which can be coated with the active compound.
  • compositions of the invention may be employed in any conventional form, for example in the form of a twin pack, a powder for dry seed treatment (DS), an emulsion for seed treatment (ES), a flowable concentrate for seed treatment (FS), a solution for seed treatment (LS), a water dispersible powder for seed treatment (WS), a capsule suspension for seed treatment (CF), a gel for seed treatment (GF), an emulsion concentrate (EC), a suspension concentrate (SC), a suspo-emulsion (SE), a capsule suspension (CS), a water dispersible granule (WG), an emulsifiable granule (EG), an emulsion, water in oil (EG), an emulsion, oil in water (EW), a micro-emulsion (ME), an oil dispersion (OD), an oil miscible flowable (OF), an oil miscible liquid (OL), a soluble concentrate (SL), an ultra-low volume suspension (SU), an ultra-low volume liquid (UL), a technical concentrate (TK
  • compositions may be produced in conventional manner, e.g. by mixing the active ingredients with appropriate formulation inerts (diluents, solvents, fillers and optionally other formulating ingredients such as surfactants, biocides, anti-freeze, stickers, thickeners and compounds that provide adjuvancy effects).
  • appropriate formulation inerts diiluents, solvents, fillers and optionally other formulating ingredients such as surfactants, biocides, anti-freeze, stickers, thickeners and compounds that provide adjuvancy effects.
  • conventional slow release formulations may be employed where long lasting efficacy is intended.
  • Particularly formulations to be applied in spraying forms such as water dispersible concentrates (e.g. EC, SC, DC, OD, SE, EW, EO and the like), wettable powders and granules, may contain surfactants such as wetting and dispersing agents and other compounds that provide adjuvancy effects, e.g.
  • a seed dressing formulation is applied in a manner known per se to the seeds employing the combination of the invention and a diluent in suitable seed dressing formulation form, e.g. as an aqueous suspension or in a dry powder form having good adherence to the seeds.
  • suitable seed dressing formulation form e.g. as an aqueous suspension or in a dry powder form having good adherence to the seeds.
  • seed dressing formulations are known in the art.
  • Seed dressing formulations may contain the single active ingredients or the combination of active ingredients in encapsulated form, e.g. as slow release capsules or microcapsules.
  • the formulations include from 0.01 to 95% by weight of active ingredients, from 0 to 20% agriculturally acceptable surfactant and 10 to 99.99% solid or liquid formulation inerts and adjuvant(s), the active ingredients consisting of at least the components (A) and (B) as defined herein, and optionally other active agents, particularly microbiocides or conservatives or the like.
  • Concentrated forms of compositions generally contain in between about 2 and 80%, preferably between about 5 and 70% by weight of active ingredients.
  • Application forms of formulation may for example contain from 0.01 to 20% by weight, preferably from 0.01 to 5% by weight of active ingredients. Whereas commercial products will preferably be formulated as concentrates, the end user will normally employ diluted formulations.
  • Mucoromycetes such as Choanephora cucurbitarum. Mucor spp.; Rhizopus arrhizus; as well as diseases caused by other species and genera closely related to those listed above.
  • a plant includes a useful plant and/or crop.
  • locus means fields in or on which plants are growing, or where seeds of cultivated plants are sown, or where seed will be placed into the soil. It includes soil, seeds, and seedlings, as well as established vegetation.
  • plant propagation material is understood to denote generative parts of the plant, such as seeds, which can be used for the multiplication of the latter, and vegetative material, such as cuttings or tubers, for example potatoes. There may be mentioned for example seeds (in the strict sense), roots, fruits, tubers, bulbs, rhizomes and parts of plants. Germinated plants and young plants which are to be transplanted after germination or after emergence from the soil, may also be mentioned. These young plants may be protected before transplantation by a total or partial treatment by immersion. Preferably “plant propagation material” is understood to denote seeds.
  • Useful plants and / or target crops in accordance with the invention include conventional as well as genetically enhanced or engineered varieties such as, for example, insect resistant (e.g. Bt. and VIP varieties) as well as disease resistant, herbicide tolerant (e.g. glyphosate- and glufosinate-resistant maize varieties) and nematode tolerant varieties.
  • Useful plants include plants transformed by the use of recombinant DNA techniques, for example, to be capable of synthesising one or more selectively acting toxins, such as are known, for example, from toxin-producing bacteria.
  • toxins which can be expressed include 8-endotoxins, vegetative insecticidal proteins (Vip), insecticidal proteins of bacteria colonising nematodes, and toxins produced by scorpions, arachnids, wasps and fungi.
  • Vip vegetative insecticidal proteins
  • insecticidal proteins of bacteria colonising nematodes include toxins produced by scorpions, arachnids, wasps and fungi.
  • Plants, including target crops and/or useful plants to be protected in a method of the invention typically comprise perennial and annual crops, such as berry plants for example blackberries, blueberries, cranberries, raspberries and strawberries; cereals for example barley, maize (corn), millet, oats, rice, rye, sorghum triticale and wheat; fibre plants for example cotton, flax, hemp, jute and sisal; field crops for example sugar and fodder beet, coffee, hops, mustard, oilseed rape (canola), poppy, sugar cane, sunflower, tea and tobacco; fruit trees for example apple, apricot, avocado, banana, cherry, citrus, nectarine, peach, pear and plum; grasses for example Bermuda grass, bluegrass, bentgrass, centipede grass, fescue, ryegrass, St.
  • perennial and annual crops such as berry plants for example blackberries, blueberries, cranberries, raspberries and strawberries
  • cereals for example barley, maize
  • Augustine grass and Zoysia grass herbs such as basil, borage, chives, coriander, lavender, lovage, mint, oregano, parsley, rosemary, sage and thyme; legumes for example beans, lentils, peas and soya beans; nuts for example almond, cashew, ground nut, hazelnut, peanut, pecan, pistachio and walnut; palms for example oil palm; ornamentals for example flowers, shrubs and trees; other trees, for example cacao, coconut, olive and rubber; vegetables for example asparagus, aubergine, broccoli, cabbage, carrot, cucumber, garlic, lettuce, marrow, melon, okra, onion, pepper, potato, pumpkin, rhubarb, spinach and tomato; and vines for example grapes.
  • herbs such as basil, borage, chives, coriander, lavender, lovage, mint, oregano, parsley, rosemary, sage and thyme
  • legumes for example beans, lentils, peas and soya beans
  • An effective amount of component A comprising Streptomyces as disclosed herein above comprises from 1 g to 10 kg / per hectare (ha), such as from 5 g to 5 kg, such as from 10 g to 1 kg / ha, such as from 50 g to 800 g / ha, such as from 100 g to 700 g / ha, such as from 200 to 600 g / ha.
  • the weight in g and kg is dry weight of the Streptomyces.
  • composition according to the present invention can be applied either preventative, meaning prior to disease development or curative, meaning after disease development.
  • the present invention relates to a plant, plant propagation material, the locus thereof and/or a harvested food crop comprising a composition as disclosed herein.
  • a plant, plant propagation material, the locus thereof and/or a harvested food crop comprising a composition as disclosed herein.
  • a composition comprising components (A) and (B) as active ingredients can be a composition wherein component (A) comprises a Streptomyces chrestomyceticus as disclosed herein, such as a Streptomyces sp. Saigon413, deposited at the Westerdijk institute under accession number CBS149411 , and wherein component (B) comprises one or more of the following components:
  • lecontei NPV niclosamide-olamine
  • nicotine nicotine sulfate, nikkomycins, nitenpyram, nithiazine, nitrapyrin, nitrilacarb, nitrothal-isopropyl, norbormide, nornicotine, novaluron, noviflumuron, nuarimol, O,O,O',O'-tetrapropyl dithiopyrophosphate, octadeca-2,13-dien-1-yl acetate, octadeca-2,13-dien-1-yl acetate, octhilinone, ofurace, oleic acid, omethoate, orfralure, Orius spp., orysastrobin, osthol, ostramone, oxadixyl, oxamate, oxamyl, oxantel pamoate, oxasul
  • Example 1.6 Lipopeptide compound of Formula II Purification of a lipopeptide according to Formula II (Formula ll(a) and Formula ll(b))
  • the lipopeptides were purified from the ethyl acetate fraction by preparative reverse phase (C18) HPLC. The lipopeptides were relatively aploar and elute in the higher organic fraction in a gradient system with 0.1% formic acid and acetonirile (0.1% formic acid). A gradient of 60% Aqueous to 40% Aqueous with the above solvents allowed separation of a lipopeptide compound according to Formula 11 (a) and Formula I l(b).
  • Experiment 1 MS OT (Orbitrap Resolution: 50,000, Scan Range (m/z): 200 to 2000, RF Lens (%): 60, AGO Target: Standard, Maximum Injection Time Mode: Auto, Microscans: 1 , Data Type: Profile, Polarity: Both), Experiment 2: tMS2 OT CID (MSn Level (n): 2, Isolation Window (m/z): 1.0, Activation Type: CID, CID Collision Energy (%): 30, Detector Type: Orbitrap, Orbitrap Resolution: 30,000, RF Lens (%): 60, Polarity: Positive),
  • Experiment 3 tMS2 OT HCD (MSn Level (n): 2, Isolation Window (m/z): 1 .0, Activation Type: HCD, HCD Collision Energy (%): 30, Detector Type: Orbitrap, Orbitrap Resolution: 30,000, RF Lens (%): 60, Polarity: Positive),
  • Experiment 4 tMS3 OT HCD (MSn Level (n): 3, Isolation Window (m/z): 1.6, Activation Type: HCD, HCD Collision Energy (%): 30, MS2 Isolation Window (m/z): 2, MS2 Activation Type: HCD, MS2 HCD Collision Energy (%): 30, Detector Type: Orbitrap, Orbitrap Resolution: 30,000, RF Lens (%): 60, Polarity: Positive).
  • the mass spectrometer was connected to a Vanquish Flex UHPLC from Thermo Scientific using a Vanquish Split Sampler FT, Vanquish Binary Pump F, Vanquish Column Compartment H, Vanquish Diode Array Detector FG and Vanquish Charged Aerosol Detector.
  • the molecular composition and mass of a lipopeptide according to Formula I l(a) and Formula I l(b) was determined using the results of liquid chromatography and high-resolution mass spectrometry as disclosed above.
  • the lipopeptide compounds of Formula 11 (a) and 11 (b) have the following composition.
  • Liquid Chromatography Conditions included: Kinetex Polar C18 column 100A 4.6x100mm, P.N. H17-055453. Temp: 40°C, DAD wavelength range: 250 to 260nm, Solvent gradient: Solvent A: H2O with 0.1 % formic acid, Solvent B: CH3CN with 0.1 % formic acid, gradient: Omin 10% B, 90% A; 1min 10% B, 90% A; 6.50min 95% B, 5% A; 8.00min 95% B, 5% A; 9.00min 10% B, 90% A; 10. OOmin 10% B, 90% A, Flow rate: 1.0ml/min, Injection volume: 5 uL, Total run time: 10. Omin. Under these conditions, the polyene compound had a retention time of 5.55-5.57 minutes.
  • the molecular composition and mass of the polyene compound was determined using the results of liquid chromatography and high-resolution mass spectrometry as disclosed above.
  • the polyene compound has a molecular composition C67H115NO25 and exact mass of 1333.7758.
  • Example 2.1 In vitro efficacy of a mixture of Streptomyces chrestomyceticus CBS149411 and a second compound against Pythium ultimum, Fusarium culmorum, Monographella nivalis syn. Microdochium nivale, Fusarium nivale, Septoria tritici, Glomerella lagenarium syn. Colletotrichum lagenarium, Botrytis cinerea
  • the following examples show the efficacy of a mixture of spray dried or freeze dried material of Streptomyces chrestomyceticus CBS149411 (compound A) and a second compound (compound B) against Pythium ultimum, Fusarium culmorum, Monographella nivalis syn. Microdochium nivale, Fusarium nivale, Zymoseptoria (Septoria tritici), Glomerella lagenarium syn. Colletotrichum lagenarium, and Botrytis cinerea.
  • the chemical compounds were from Syngenta or supplied by other commercial vendors.
  • An efficacy of 0 means that the growth level of the pathogen corresponds to that of the untreated control; an efficacy of 100 means that the growth level of the pathogen was fully inhibited.
  • Mycelial fragments of the pathogen prepared from a fresh liquid culture, were directly mixed into nutrient broth (potato dextrose broth). After placing a (DMSO) solution of the test compounds into a microtiter plate (96-well format), the nutrient broth containing the mycelial fragments was added. The test plates were incubated at 24°C and the inhibition of growth was determined after 48 hrs.
  • nutrient broth potato dextrose broth
  • Conidia of the fungus from cryogenic storage were directly mixed into nutrient broth (potato dextrose broth).
  • a DMSO solution of the test compounds was placed into a microtiter plate (96-well format) and the nutrient broth containing the fungal spores was added to it.
  • the test plates were incubated at 24°C and the inhibition of growth was determined after 48 hrs.
  • Conidia of the fungus from cryogenic storage were directly mixed into nutrient broth (potato dextrose broth).
  • a DMSO solution of the test compounds was placed into a microtiter plate (96-well format) and the nutrient broth containing the fungal spores was added to it.
  • the test plates were incubated at 24°C and the inhibition of growth was determined after 72 hrs.
  • Wheat or rice seedlings 14days old were sprayed with S. chrestomyceticus CBS149411 formulated as OD40% alone, or mixed with a second product before spraying the plants and subsequent infection with a fungal pathogen.
  • the efficacy of the mixture was also compared to the efficacy of the solo second compound product.
  • the mixture of the two components was done in water before the mixture was loaded into the tank of the spray equipment.
  • the spray volume was 200L/ha
  • the application was executed with a boom sprayer-type equipment in a glasshouse setting. Both components were mixed at different use rates, resulting in a multitude of different mixture ratios.
  • CBS149411 formulated as OD40% was sprayed at a use rate of 500g/ha (active ingredient), and a second product at a use rate of 100g/ha (active ingredient), resulting in a ratio of 5:1 (CBS 149411 : 2nd compound).
  • Mixtures resulting in 30% or more reduction of disease symptoms were seen as effective to provide a means for disease control or disease reduction.
  • Bayer Bayer AG, Crop Science Division, Alfred-Nobel-Str. 50, 40789 Monheim am Rhein, GERMANY Corteva: Corteva agriscience, 9330 Zionsville Road, Indianapolis, IN 46268, USA
  • Mitsui Chemicals Mitsui Chemicals, Inc, Tokyo Midtown Yaesu, Yaesu Central Tower, 2-2-1 Yaesu, Chuo-ku, Tokyo 104-0028, JAPAN
  • Zhejiang Xinnong Chemical Zhejiang XinNong Chemical Co., Ltd, 11 F , Poly Center, No.277 Xintang Road, Jianggan District, Hangzhou, Zhejiang, P.R. CHINA
  • Puccinia recondita 14 days old wheat plants variety Arina were inoculated by spraying them with a spore suspension one day after application (spore suspension at 80,000 spores per ml in water supplemented with Tween20 at 0.1%). After an incubation period of 1 day at 20° C and 95% relative humidity, the inoculated test plants were kept at 20° C and 60% relative humidity in a greenhouse. The percentage leaf area covered by disease was assessed visually when an appropriate level of disease appeared on untreated check plants (9 - 12 days after infection).
  • Zymoseptoria tritici 14 days old wheat plants variety Riband were inoculated by spraying a spore suspension on them one day after application (1 .5 Mio spores per ml in water supplemented with 0.01 % Tween20). After an incubation period of 4 days at 22°C/21 °C (day/night) and 95% relative humidity, the inoculated test plants were kept at 22°C/21°C (day/night) and 70% relative humidity in a greenhouse. Efficacy was assessed directly when an appropriate level of disease appeared on untreated check plants (14 - 19 days after application). The isolate used is a recent field isolate expressing tolerance to DMI fungicides, SDHI fungicides and Qol fungicides.
  • Pyricularia oryzae (EPPO code: PYRIOR): 3 week old rice plants cv. Balilla were treated with the formulated test compound in a spray chamber. Two days after application rice plants were inoculated by spraying a spore suspension (1 x 10 5 conidia/ml) on the test plants. After an incubation period of 6 days at 25° C and 95% relative humidity the disease incidence was assessed.

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Abstract

La présente invention concerne une composition comprenant des composants (A) et (B) en tant que principes actifs, le composant (A) comprenant un Streptomyces chrestomyceticus et le composant (B) étant un composé choisi dans le groupe constitué par le prothioconazole, le difénoconazole, le méfentrifluconazole, l'hexaconazole, le propiconazole, le bromuconazole, la fenpropidine, la spiroxamine, l'isoprothiolane, le pydiflumétofène, le benzovindiflupyr, l'isoflucypram, l'isopyrazam, le fluxapyroxad, le cyprodinil, l'azoxystrobine, la pyraclostrobine, le métyltétraprole, le proquinazid, le tricyclazole, le florylpicoxamide, le fenpicoxamide, le N-(2,4-diméthyl-1-phénylpentan-2-yl)-8-fluoroquinoline-3-carboxamide, l'ipflufénoquine, la quinofumelin, le zinc thiazole, le folpet, le chlorothalonil, l'acibenzolar-S-méthyle, le fosétyl-aluminium, l'acide oxolinique, l'anisiflupurine, l'inpyrfluxam, le métalaxyl, le métalaxyl-M, le triticonazole, le penthiopyrad, le sedaxane, le thiabendazole, l'imidaclopride, le thiaméthoxam, le fludioxonil, la fluoxastrobine, le silthiofam, le chlorantraniliprole, l'éthaboxam, l'ipconazole, le cyantraniliprole, l'oxathiapiproline, le fluopyram, le picarbutrazox, le cyclobutrifluram, l'isocycloséram et la fluoxapiproline. L'invention concerne en outre un procédé de lutte contre des maladies phytopathogènes, ou de prévention de celles-ci, de préférence de champignons phytopathogènes, sur une plante ou sur un matériau de propagation de plante et/ou sur des cultures alimentaires récoltées, qui comprend l'application à la plante, sur un matériau de propagation de plante, son locus et/ou sur des cultures alimentaires récoltées de la composition selon la présente invention.
PCT/EP2025/059131 2024-04-04 2025-04-03 Composition fongicide Pending WO2025210149A1 (fr)

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Citations (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5356624A (en) 1993-04-23 1994-10-18 The United States Of America As Represented By The Secretary Of Agriculture Biological treatment for controlling wood deteriorating fungi
WO2006078939A1 (fr) 2005-01-21 2006-07-27 Dow Agrosciences Llc Utilisation de la malonomicine et d'analogues dans des applications fongicides
WO2011138281A2 (fr) 2010-05-06 2011-11-10 Bayer Cropscience Ag Procédé de production de dithiine-tétracarboxy-diimides
WO2013092224A1 (fr) 2011-12-21 2013-06-27 Basf Se Utilisation de composés de type strobilurine pour combattre des champignons phytopathogènes résistants aux inhibiteurs du site qo
WO2014006945A1 (fr) 2012-07-04 2014-01-09 アグロカネショウ株式会社 Dérivé d'ester d'acide 2-aminonicotinique et bactéricide le contenant comme principe actif
WO2014095675A1 (fr) 2012-12-19 2014-06-26 Bayer Cropscience Ag Utilisation de carboxamides difluorométhyl-nicotinique-indanyle comme fongicides
WO2015185485A1 (fr) 2014-06-06 2015-12-10 Basf Se Utilisation d'oxadiazoles substitués pour lutter contre des fongus phytopathogènes
WO2015191789A2 (fr) 2014-06-10 2015-12-17 The Board Of Trustees Of The University Of Illinois Criblage fondé sur la réactivité utilisable en vue de la découverte de produits naturels
CN103960287B (zh) * 2014-03-31 2016-02-17 中国计量学院 一种防治褐飞虱的混合配方制剂
WO2016156290A1 (fr) 2015-04-02 2016-10-06 Bayer Cropscience Aktiengesellschaft Nouveaux dérivés d'imidazole à substitution en position 5
WO2017016915A1 (fr) 2015-07-24 2017-02-02 Basf Se Composés pyridine utiles pour lutter contre des champignons phytopathogènes
WO2017029179A1 (fr) 2015-08-14 2017-02-23 Bayer Cropscience Aktiengesellschaft Dérivés de triazole, leurs intermédiaires et leur utilisation comme fongicides
WO2017055473A1 (fr) 2015-10-02 2017-04-06 Syngenta Participations Ag Dérivés d'oxadiazole microbiocides
WO2017153380A1 (fr) 2016-03-10 2017-09-14 Syngenta Participations Ag Dérivés microbiocides de quinoléine (thio)carboxamide
WO2017178245A1 (fr) 2016-04-11 2017-10-19 Basf Se Oxadiazoles substitués pour lutter contre des champignons phytopathogènes
WO2017207362A1 (fr) 2016-05-30 2017-12-07 Syngenta Participations Ag Dérivés de thiazole microbiocides
WO2018153707A1 (fr) 2017-02-22 2018-08-30 Basf Se Formes cristallines d'un composé de type strobilurine pour lutter contre des champignons phytopathogènes
WO2019093522A1 (fr) 2017-11-13 2019-05-16 株式会社クレハ Dérivé d'azole, composé intermédiaire, procédé de production d'un dérivé d'azole, agent à usage agricole et horticole, et agent de protection de matériau à usage industriel
WO2019105933A1 (fr) 2017-11-29 2019-06-06 Syngenta Participations Ag Dérivés de thiazole microbiocides
WO2020056090A1 (fr) 2018-09-14 2020-03-19 Fmc Corporation Halométhyl cétones et hydrates fongicides
WO2020097012A1 (fr) 2018-11-06 2020-05-14 Fmc Corporation Tolyles substitués utilisés en tant que fongicides
WO2020109511A1 (fr) 2018-11-30 2020-06-04 Syngenta Crop Protection Ag Dérivés de 2-acylamino-thiazole-4-carboxamide microbiocides
WO2020109509A1 (fr) 2018-11-30 2020-06-04 Syngenta Participations Ag Dérivés de thiazole microbiocides
WO2020127780A1 (fr) 2018-12-20 2020-06-25 Bayer Aktiengesellschaft Hétérocyclyl-pyridazine utilisée en tant que composés fongicides
CN111543439A (zh) * 2020-05-19 2020-08-18 渭南职业技术学院 一种农用杀菌组合物
WO2020193387A1 (fr) 2019-03-22 2020-10-01 Syngenta Crop Protection Ag Composés fongicides
WO2020256113A1 (fr) 2019-06-21 2020-12-24 日本農薬株式会社 Composé d'oxadiazole ou sels de celui-ci, bactéricide agricole/horticole contenant ledit composé, et procédé d'utilisation associé
WO2021183707A2 (fr) 2020-03-11 2021-09-16 Fmc Corporation Halométhyl cétones et hydrates fongicides et leurs mélanges
WO2021244952A1 (fr) 2020-06-03 2021-12-09 Syngenta Crop Protection Ag Dérivés microbiocides
WO2021249928A1 (fr) 2020-06-10 2021-12-16 Basf Se Utilisation de composés de type strobilurine pour lutter contre des champignons phytopathogènes, contenant une substitution d'acides aminés f129l dans la protéine cytochrome b mitochondrial conférant une résistance à des inhibiteurs de qo v
WO2021249800A1 (fr) 2020-06-10 2021-12-16 Basf Se Composés de [1,2,4]triazole substitués utilisés en tant que fongicides
WO2021255093A1 (fr) 2020-06-19 2021-12-23 Bayer Aktiengesellschaft Combinaison de composés actifs
WO2021255070A1 (fr) 2020-06-18 2021-12-23 Bayer Aktiengesellschaft Combinaisons de composés actifs
WO2022033906A1 (fr) 2020-08-11 2022-02-17 Basf Se Utilisation de composés de type strobilurine pour lutter contre des champignons phytopathogènes, contenant une substitution d'acide aminé f129l dans la protéine cytochrome b mitochondriale conférant une résistance à des inhibiteurs qo viii
WO2022038180A1 (fr) 2020-08-18 2022-02-24 Aphea.Bio Nv Moyens et procédés de lutte contre les pathhogènes et les nuisibles dans les plantes
WO2022133114A1 (fr) 2020-12-17 2022-06-23 Fmc Corporation Oxadiazoles fongicides et leurs mélanges
CN116616300A (zh) * 2023-04-12 2023-08-22 河北兴柏农业科技股份有限公司 一种含阿维菌素和氯虫苯甲酰胺的悬浮剂及其制备方法
CN116806848A (zh) * 2023-06-16 2023-09-29 石河子大学 一种用于防治土传病害杀菌组合物及其应用
WO2024074637A1 (fr) * 2022-10-07 2024-04-11 Syngenta Crop Protection Ag Moyens et procédés de lutte contre des pathogènes et des organismes nuisibles chez des plantes

Patent Citations (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5356624A (en) 1993-04-23 1994-10-18 The United States Of America As Represented By The Secretary Of Agriculture Biological treatment for controlling wood deteriorating fungi
WO2006078939A1 (fr) 2005-01-21 2006-07-27 Dow Agrosciences Llc Utilisation de la malonomicine et d'analogues dans des applications fongicides
EP1860939A1 (fr) 2005-01-21 2007-12-05 Dow Agrosciences LLC Utilisation de la malonomicine et d'analogues dans des applications fongicides
WO2011138281A2 (fr) 2010-05-06 2011-11-10 Bayer Cropscience Ag Procédé de production de dithiine-tétracarboxy-diimides
WO2013092224A1 (fr) 2011-12-21 2013-06-27 Basf Se Utilisation de composés de type strobilurine pour combattre des champignons phytopathogènes résistants aux inhibiteurs du site qo
WO2014006945A1 (fr) 2012-07-04 2014-01-09 アグロカネショウ株式会社 Dérivé d'ester d'acide 2-aminonicotinique et bactéricide le contenant comme principe actif
WO2014095675A1 (fr) 2012-12-19 2014-06-26 Bayer Cropscience Ag Utilisation de carboxamides difluorométhyl-nicotinique-indanyle comme fongicides
CN103960287B (zh) * 2014-03-31 2016-02-17 中国计量学院 一种防治褐飞虱的混合配方制剂
WO2015185485A1 (fr) 2014-06-06 2015-12-10 Basf Se Utilisation d'oxadiazoles substitués pour lutter contre des fongus phytopathogènes
WO2015191789A2 (fr) 2014-06-10 2015-12-17 The Board Of Trustees Of The University Of Illinois Criblage fondé sur la réactivité utilisable en vue de la découverte de produits naturels
WO2016156290A1 (fr) 2015-04-02 2016-10-06 Bayer Cropscience Aktiengesellschaft Nouveaux dérivés d'imidazole à substitution en position 5
WO2017016915A1 (fr) 2015-07-24 2017-02-02 Basf Se Composés pyridine utiles pour lutter contre des champignons phytopathogènes
WO2017029179A1 (fr) 2015-08-14 2017-02-23 Bayer Cropscience Aktiengesellschaft Dérivés de triazole, leurs intermédiaires et leur utilisation comme fongicides
WO2017055473A1 (fr) 2015-10-02 2017-04-06 Syngenta Participations Ag Dérivés d'oxadiazole microbiocides
WO2017153380A1 (fr) 2016-03-10 2017-09-14 Syngenta Participations Ag Dérivés microbiocides de quinoléine (thio)carboxamide
WO2017178245A1 (fr) 2016-04-11 2017-10-19 Basf Se Oxadiazoles substitués pour lutter contre des champignons phytopathogènes
WO2017207362A1 (fr) 2016-05-30 2017-12-07 Syngenta Participations Ag Dérivés de thiazole microbiocides
WO2018153707A1 (fr) 2017-02-22 2018-08-30 Basf Se Formes cristallines d'un composé de type strobilurine pour lutter contre des champignons phytopathogènes
WO2019093522A1 (fr) 2017-11-13 2019-05-16 株式会社クレハ Dérivé d'azole, composé intermédiaire, procédé de production d'un dérivé d'azole, agent à usage agricole et horticole, et agent de protection de matériau à usage industriel
WO2019105933A1 (fr) 2017-11-29 2019-06-06 Syngenta Participations Ag Dérivés de thiazole microbiocides
WO2020056090A1 (fr) 2018-09-14 2020-03-19 Fmc Corporation Halométhyl cétones et hydrates fongicides
WO2020097012A1 (fr) 2018-11-06 2020-05-14 Fmc Corporation Tolyles substitués utilisés en tant que fongicides
WO2020109511A1 (fr) 2018-11-30 2020-06-04 Syngenta Crop Protection Ag Dérivés de 2-acylamino-thiazole-4-carboxamide microbiocides
WO2020109509A1 (fr) 2018-11-30 2020-06-04 Syngenta Participations Ag Dérivés de thiazole microbiocides
WO2020127780A1 (fr) 2018-12-20 2020-06-25 Bayer Aktiengesellschaft Hétérocyclyl-pyridazine utilisée en tant que composés fongicides
WO2020193387A1 (fr) 2019-03-22 2020-10-01 Syngenta Crop Protection Ag Composés fongicides
WO2020256113A1 (fr) 2019-06-21 2020-12-24 日本農薬株式会社 Composé d'oxadiazole ou sels de celui-ci, bactéricide agricole/horticole contenant ledit composé, et procédé d'utilisation associé
WO2021183707A2 (fr) 2020-03-11 2021-09-16 Fmc Corporation Halométhyl cétones et hydrates fongicides et leurs mélanges
CN111543439A (zh) * 2020-05-19 2020-08-18 渭南职业技术学院 一种农用杀菌组合物
WO2021244952A1 (fr) 2020-06-03 2021-12-09 Syngenta Crop Protection Ag Dérivés microbiocides
WO2021249928A1 (fr) 2020-06-10 2021-12-16 Basf Se Utilisation de composés de type strobilurine pour lutter contre des champignons phytopathogènes, contenant une substitution d'acides aminés f129l dans la protéine cytochrome b mitochondrial conférant une résistance à des inhibiteurs de qo v
WO2021249800A1 (fr) 2020-06-10 2021-12-16 Basf Se Composés de [1,2,4]triazole substitués utilisés en tant que fongicides
WO2021255070A1 (fr) 2020-06-18 2021-12-23 Bayer Aktiengesellschaft Combinaisons de composés actifs
WO2021255093A1 (fr) 2020-06-19 2021-12-23 Bayer Aktiengesellschaft Combinaison de composés actifs
WO2022033906A1 (fr) 2020-08-11 2022-02-17 Basf Se Utilisation de composés de type strobilurine pour lutter contre des champignons phytopathogènes, contenant une substitution d'acide aminé f129l dans la protéine cytochrome b mitochondriale conférant une résistance à des inhibiteurs qo viii
WO2022038180A1 (fr) 2020-08-18 2022-02-24 Aphea.Bio Nv Moyens et procédés de lutte contre les pathhogènes et les nuisibles dans les plantes
WO2022133114A1 (fr) 2020-12-17 2022-06-23 Fmc Corporation Oxadiazoles fongicides et leurs mélanges
WO2024074637A1 (fr) * 2022-10-07 2024-04-11 Syngenta Crop Protection Ag Moyens et procédés de lutte contre des pathogènes et des organismes nuisibles chez des plantes
CN116616300A (zh) * 2023-04-12 2023-08-22 河北兴柏农业科技股份有限公司 一种含阿维菌素和氯虫苯甲酰胺的悬浮剂及其制备方法
CN116806848A (zh) * 2023-06-16 2023-09-29 石河子大学 一种用于防治土传病害杀菌组合物及其应用

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
"nematodes and seed treatments", vol. 412, 6 December 2012, SPRINGER, article "the Nouryon formulator toolbox and in: Formulation of Microbial Biopesticides: Beneficial microorganisms", pages: 412
COLBY, S.R.: "Calculating synergistic and antagonistic responses of herbicide combination", WEEDS, vol. 15, 1967, pages 20 - 22, XP001112961
KONDO, H.ORITANI, T.KIYOTA, H: "Synthesis and antifungal activity of the four stereoisomers of streptimidone, a glutarimide antibiotic from Streptomyces rimosus forma paromomycinus", EUR. J. ORG. CHEM., vol. 20, 2000, pages 3459 - 3462, XP072101339, DOI: 10.1002/1099-0690(200010)2000:20<3459::AID-EJOC3459>3.0.CO;2-F
KUTCHMA ET AL., BIOTECHNIQUES, vol. 24, no. 3, 1998, pages 452 - 457
LAW ET AL., NATURE CATALYS, vol. 1, December 2018 (2018-12-01), pages 977 - 984
LEE ET AL., J. OF ANTIBIOTICS, vol. 73, 2020, pages 184 - 188
MICHEL-ACEVES A. C. ET AL: "Control Alternatives for Damping-Off in Tomato Seedling Production", vol. 88, no. 3, 1 January 2019 (2019-01-01), pages 325 - 333, XP093202467, ISSN: 1851-5657, Retrieved from the Internet <URL:https://dx.doi.org/10.32604/phyton.2019.06777> DOI: 10.32604/phyton.2019.06777 *
no. 2132414-04-9
RAHILA ET AL., CURRENT MICROBIOLOGY, vol. 80, 2023, pages 107
WANG ET AL., APPL. ENVIRONMENTAL MICROBIOLOGY, vol. 76, no. 7, 2010, pages 2336

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