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WO2025127094A1 - Composition de lutte contre les organismes nuisibles, et procédé de lutte contre les maladies ou parasites des plantes mettant en œuvre cette composition - Google Patents

Composition de lutte contre les organismes nuisibles, et procédé de lutte contre les maladies ou parasites des plantes mettant en œuvre cette composition Download PDF

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Publication number
WO2025127094A1
WO2025127094A1 PCT/JP2024/043955 JP2024043955W WO2025127094A1 WO 2025127094 A1 WO2025127094 A1 WO 2025127094A1 JP 2024043955 W JP2024043955 W JP 2024043955W WO 2025127094 A1 WO2025127094 A1 WO 2025127094A1
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WIPO (PCT)
Prior art keywords
ppm
spirotetramat
mortality rate
pest
predicted
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English (en)
Japanese (ja)
Inventor
英一 山田
信行 河原
智 湯谷
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Mitsui Chemicals Crop and Life Solutions Inc
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Mitsui Chemicals Crop and Life Solutions Inc
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Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01CPLANTING; SOWING; FERTILISING
    • A01C1/00Apparatus, or methods of use thereof, for testing or treating seed, roots, or the like, prior to sowing or planting
    • A01C1/06Coating or dressing seed
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01MCATCHING, TRAPPING OR SCARING OF ANIMALS; APPARATUS FOR THE DESTRUCTION OF NOXIOUS ANIMALS OR NOXIOUS PLANTS
    • A01M1/00Stationary means for catching or killing insects
    • A01M1/20Poisoning, narcotising, or burning insects
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46N-acyl derivatives
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/02Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
    • A01N47/06Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom containing —O—CO—O— groups; Thio analogues thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01PBIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P7/00Arthropodicides
    • A01P7/02Acaricides
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01PBIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P7/00Arthropodicides
    • A01P7/04Insecticides

Definitions

  • the present invention relates to a novel combination pest control composition and a method for controlling plant diseases or plant pests using the composition.
  • compositions suitable for controlling harmful organisms such as pest insects, pathogens, and weeds.
  • mixed compositions containing multiple active ingredients are used for the purpose of simultaneously controlling various harmful organisms.
  • multiple-ingredient chemicals are simultaneously applied, such as by applying a chemical agent containing two or more active ingredients (mixture) or by mixing several chemical agents in a tank mix in a farm field.
  • the object of the present invention is to provide a pest control composition that exhibits a useful control effect, including a novel combination, and a method for controlling plant diseases or plant pests using the composition.
  • a pest control composition comprising spirotetramat and at least one compound selected from the group consisting of a phenylpyrazole compound, an isoxazoline compound, and a metadiamide compound.
  • the phenylpyrazole compound is nicofluprole
  • the isoxazoline compound is isocycloceram
  • the metadiamide compound is either brofuranilide or ciproflanilide.
  • the pest is at least one pest belonging to a family selected from the group consisting of Noctuidae, Aphididae, Tetranychidae, and Thripidae.
  • a method for controlling plant diseases or plant pests comprising applying the pest control composition according to any one of [1] to [8] to plants, seeds, or soil.
  • the present invention provides a pest control composition that exhibits an unexpectedly useful control effect, including a novel combination, and a method for controlling plant diseases or plant pests using the composition.
  • Spirotetramat is an active ingredient that belongs to Group 23 (acetyl-CoA carboxylase inhibitors) in the IRAC (insecticide mode of action classification).
  • Other active ingredients that belong to Group 23 include spirodiclofen, spiropydione, and spiromesifen.
  • the phenylpyrazole compound may be at least one compound selected from acetoprole, ethiprole, fipronil, flufiprole, nicofluprole, pyrafluprole, pyriprole, etc. Among these, it is preferable that the phenylpyrazole compound is nicofluprole.
  • the isoxazoline compound may be at least one compound selected from afoxolaner, fluralaner, fluxamethamide, isocycloseram, lotilaner, sarolaner, isoflualanum, etc. Among them, it is preferable that the isoxazoline compound is either isocycloseram or fluxamethamide.
  • the metadiamide compound may be at least one compound selected from broflanilide, cyproflanilide, piperflanilide, etc. Among these, it is preferable that the metadiamide compound is either broflanilide or cyproflanilide, and it is more preferable that the metadiamide compound is broflanilide.
  • the second component may be an active ingredient belonging to Group 30 (GABA-gated chloride channel allosteric modulators) in the IRAC.
  • GABA-gated chloride channel allosteric modulators GABA-gated chloride channel allosteric modulators
  • a metadiamide compound may be selected as the second component.
  • the metadiamide compound is either brofuranilide or ciproflanilide.
  • the pest is preferably at least one type of pest belonging to an order selected from the group consisting of Lepidoptera, Acarina, and Thripida.
  • pests belonging to the Lepidoptera or Lepidoptera orders include the HAPIALIDAE family, such as the bat moth (Endoclyta excrecens), the yellow-spotted bat (Endoclyta sinensis), and the white-spotted bat (Palpifer sexnotata), and the bat moth (Palpifer nigricans).
  • the COSSIDAE include Cossus jezoensis
  • the TORTRICIDAE include Acleris comaria, Adoxophyes orana fasciata, Adoxophyes sp., and the apple moth.
  • TINEIDAE Nemapogon granellus, Tinea translucens and others
  • BUCCULATRIGIDAE Bucculatrix pyricorella and others
  • LYONETIIDAE Peach leafminer, Lyonetia clerkella, Lyonetia prunifoliella, Bedellia somnulentella, etc.
  • GRACILLARIIDAE Gracillary moths
  • Argyresthidae includes the moth Plutella xylostella, the narrow-leaved moth Euhyponomeutoides trachydeltus, the narrow-leaved moth Xyrosaris lichenuta, and the apple moth Yponomeuta marinellus.
  • Deltocephalidae includes Macrosteles fascifrons, Nephotettix cincticeps, Nephotettix nigropictus, Nephotettix virescens, apple leafhopper (Orientus ishidai), lightning leafhopper (Recilia dorsalis), wheat leafhopper (Sorhoanus tritici), alder leafhopper (Speusotettix subfusculus), small leafhopper (Macrosteles strifrons), small leafhopper (Arboridia apicalis), etc., as for the Delphacidae (DELPHACIDAE), small brown planthopper (Laodelphax striatellus), brown planthopper (Nilaparvata lugens), sugar brown planthopper (Numata muiri), corn planthopper (Peregrinus maid
  • DIASPIDIDAE Diaspididae family
  • pests belonging to the order ACARINA include, for example, the family Tarsonemidae (Tarsonemidae), such as Polyphagotarsonemus latus, Steneotarsonemau pallidus, and Tarsonemus waitei; the family Pyemotidae (Pyemotes ventricosus); the family Eupodidae (Eupodidae), such as Penthaleus major; the family Tenuipallidae (Tenuipallidae), such as Polyphagotarsonemus latus; PIDAE include Brevipalpus lewisi, Brevipalpus obovatus, Dolichotetranychus florodanus, Tenuipalpus zhizhilashviliae, Brevipalpus russulus, Pentamerismus oregonensis, and other TUCKERELLIDAE include Tuckerella pavonifolia.
  • Tetranychidae clover spider mite (Bryobia praetiosa), false clover spider mite (Bryobia rubrioculus), apricot spider mite (Eotetranychus boreus), Michinoku spider mite (Eotetranychus geniculatus), chestnut spider mite (Eotetranychus puruni), white spider mite (Eotetranychus sexmanaculatus), Smith spider mite (Eotetranychus smithi), walnut spider mite (Eotetranychus unc) atus), Japanese cedar mite (Oligonychus hondoensis), small dwarf spider mite (Oligonychus ilicis), larch mite (Oligonychus karamatus), citrus red mite (Panonychus citri), apple red mite (Panonychus ulmi), false two-
  • the formulation of the pest control composition of this embodiment is not particularly limited, but examples thereof include dusts, granules, wettable powders, water-soluble agents, oils, flowable agents, liquids, emulsions, capsules, and the like.
  • Other components can be blended into the pest control composition for various purposes.
  • the other components are not particularly limited as long as they are substances used in pesticides, but examples thereof include carriers, surfactants, binders, disintegrants, stabilizers, pH adjusters, antibacterial agents, antifungal agents, thickeners, defoamers, antifreeze agents, colorants, bulking agents, preservatives, and the like.
  • Carriers include solid carriers, liquid carriers, and gas carriers.
  • Solid carriers include mineral powders, synthetic resin powders, powders derived from animals and plants, and inorganic salts.
  • Liquid carriers include water, protic organic solvents, and aprotic organic solvents.
  • Gaseous carriers include air, nitrogen, and carbon dioxide.
  • Surfactants include nonionic surfactants, anionic surfactants, cationic surfactants, and amphoteric surfactants.
  • Stabilizers include antioxidants and ultraviolet absorbers.
  • pH adjusters include inorganic acids, organic acids, inorganic bases, and organic bases.
  • Colorants include inorganic pigments, organic pigments, and dyes.
  • the above-mentioned pests are preferably plant pests, but may also be fungi that cause plant diseases.
  • plant diseases caused by fungi may be controlled by controlling plant pests.
  • a method for controlling plant diseases or plant pests can be carried out by applying the above-mentioned pest control composition to plants, seeds, or soil.
  • methods for applying the pest control composition include foliage spraying to individual plants, seedling box treatment, spraying on the soil surface, soil incorporation after spraying on the soil surface, injection into soil, incorporation into seedling culture medium, seedbed treatment, soil incorporation after injection in soil, soil drench, soil incorporation after soil drench, spraying on plant seeds, smearing on plant seeds, immersing on plant seeds, or dressing on plant seeds.
  • the composition of the present invention is sufficiently effective in any application method normally used by those skilled in the art.
  • the time (period) between application of either one of the pest control compositions containing spirotetramat as an active ingredient and the pest control composition containing at least one of a phenylpyrazole compound, an isoxazoline compound, and a metadiamide compound as an active ingredient and application of the other composition is not particularly limited as long as it is effective in controlling plant diseases or plant pests, but for example, it is 1 minute to 2 weeks after application of either one of the compositions, preferably 5 minutes to 1 week after application of either one of the compositions, and more preferably 10 minutes to 3 days after application of either one of the compositions.
  • which pest control composition is applied first is not particularly limited as long as it is effective in controlling plant diseases or plant pests, but it can be appropriately selected and determined depending on the target plant pests, plants, and other application environments.
  • the contents of the first and second components in the pest control composition of this embodiment are not particularly limited as long as the effect is exhibited. Two or more components may be used in combination as the second component.
  • the mixing ratio of the first and second components is also not particularly limited as long as the effect is exhibited, but the mixing ratio (mass ratio) of the first component/second component is preferably 1/300 to 300/1, more preferably 1/150 to 150/1, and even more preferably 1/50 to 50/1.
  • the concentration of spirotetramat may be 0.336 ppm or more
  • the concentration of broflanilide may be 0.075 ppm or more.
  • the concentration of spirotetramat may be 1.12 ppm or more
  • the concentration of isocycloceram may be 0.6 ppm or more.
  • the concentration of spirotetramat may be 0.336 ppm or more
  • the concentration of ciprofuranilide may be 0.075 ppm or more.
  • the concentration of spirotetramat may be 0.0336 ppm or more
  • the concentration of brofuranilide may be 0.0075 ppm or more.
  • the concentration of spirotetramat may be 0.0336 ppm or more
  • the concentration of ciprofuranilide may be 0.025 ppm or more.
  • the concentration of spirotetramat may be 0.00336 ppm or more
  • the concentration of fluxamethamide may be 0.015 ppm or more.
  • the concentration of spirotetramat may be 1.12 ppm or more
  • the concentration of isocycloceram may be 0.4 ppm or more.
  • the concentration of spirotetramat may be 0.336 ppm or more
  • the concentration of broflanilide may be 0.025 ppm or more.
  • the concentration of spirotetramat may be 0.00336 ppm or more
  • the concentration of isocycloceram may be 0.006 ppm or more.
  • the concentration of spirotetramat may be 0.00336 ppm or more
  • the concentration of fluxamethamide may be 0.5 ppm or more.
  • the concentration of spirotetramat may be 0.336 ppm or more
  • the concentration of ciprofuranilide may be 0.025 ppm or more.
  • the concentration of spirotetramat may be 0.0112 ppm or more, and the concentration of brofuranilide may be 0.0075 ppm or more.
  • Sample preparation and test method (1) Sample preparation and test method for evaluation of cotton aphid A 1% agar solution was prepared, and placed in a glass tube bottle with a diameter of 40 mm and a depth of 60 mm to 80%, and allowed to solidify at room temperature. Then, a small amount of 1% agar was added as an adhesive, and a cucumber leaf with a diameter of 35 mm was placed on it upside down. Approximately 7 adult cotton aphids were released, and the glass tube was placed upside down on a grid and left in a thermostatic chamber at 25°C. After 24 hours, the adults were removed, and the first instar larvae were counted.
  • test agent was prepared to a predetermined concentration using 0.03% Gramin S solution.
  • the test agent was transferred to a cup, and cabbage leaves were placed in it and immersed for 15 seconds. After air drying, the leaves were transferred to another cup, and Spodoptera litura 3rd instar larvae were released.
  • the samples were left in a thermostatic chamber at 25°C, and after a predetermined number of days, the number of live insects and dead insects were counted, and the mortality rate % ((number of dead insects/number of test insects) * 100) was calculated.
  • test agent was prepared to a specified concentration using 0.03% Gramin S solution.
  • the drug solution was transferred to a cup, and cabbage leaves were placed in it and immersed for 15 seconds. After air drying, the solution was transferred to another cup, and diamondback moth 3rd instar larvae were released.
  • the samples were left in a thermostatic chamber at 25°C, and after a specified number of days, the number of live insects and dead insects were counted, and the mortality rate % ((number of dead insects/number of test insects) * 100) was calculated.
  • the test agent was prepared to the specified concentration using 0.01% Gramin S solution.
  • the counted kidney bean leaf disks were sprayed with 7 ml of the test agent using a rotating spray tower, air-dried, and then left in a thermostatic room at 25°C. After a specified number of days, the number of unhatched eggs, live insects, dead insects, and insects that had escaped from the leaves were counted under a microscope, and the total egg killing rate % ((unhatched eggs/number of test eggs) * 100) + insect mortality rate % (((number of dead insects + number of escaping insects)/number of test eggs) * 100) was calculated.
  • test agent was prepared to the specified concentration using 0.03% Gramin S solution. 7 ml of the test agent was sprayed into the counted glass tube bottles using a rotating spray tower and air-dried. The bottles were then left in a thermostatic chamber at 25°C, and after a specified number of days, the number of live and dead insects parasitizing the leaves was counted, and the mortality rate % ((number of dead insects/number of test insects) * 100) was calculated.
  • Table 1 below shows the mortality rate when spirotetramat is used alone.
  • the mortality rate of the combined use of spirotetramat 11.2 ppm and broflanilide 2.5 ppm was 47.0% 1 day after treatment, 84.3% 2 days after treatment, and 88.0% 3 days after treatment. This result showed a synergistic effect compared to the mortality rate of spirotetramat 11.2 ppm alone (6.5% 1 day after treatment, 40.2% 2 days after treatment, and 56.5% 3 days after treatment) and the mortality rate of broflanilide 2.5 ppm alone (0.0% 1 day after treatment, 8.3% 2 days after treatment, and 26.2% 3 days after treatment) predicted from the mortality rate (6.5% 1 day after treatment, 45.2% 2 days after treatment, and 67.9% 3 days after treatment).
  • Table 6 shows the mortality rates when spirotetramat 3.36 ppm and broflanilide 0.075, 0.25, 0.75, and 2.5 ppm were used in combination.
  • the figures in parentheses indicate the mortality rates predicted by the Colby formula. As a result, three days after treatment, the mortality rates were 45.5, 48.0, 34.9, and 60.9%, respectively. These results showed a synergistic effect compared to the mortality rates predicted by the Colby formula (22.4, 22.4, 24.7, and 42.7%, respectively).
  • the predicted mortality rates for each concentration combination can be calculated using the Colby formula described above.
  • Table 14 shows the mortality rates when spirotetramat 1.12 ppm and isocycloceram 0.6, 2.0, and 6.0 ppm were used in combination.
  • the figures in parentheses indicate the mortality rates predicted by the Colby formula. As a result, two days after treatment, the mortality rates were 37.3%, 52.3%, and 65.2%, respectively. This result showed a synergistic effect compared to the mortality rates predicted by the Colby formula (34.5%, 35.2%, and 53.7%, respectively).
  • Table 15 below shows the mortality rates when spirotetramat 3.36 ppm and isocycloceram 2.0, 6.0, and 20.0 ppm were used in combination.
  • the figures in parentheses indicate the mortality rates predicted by the Colby formula. As a result, two days after treatment, the mortality rates were 60.8%, 57.7%, and 80.2%, respectively. This result showed a synergistic effect compared to the mortality rates predicted by the Colby formula (38.6%, 56.2%, and 73.3%, respectively).
  • Table 16 below shows the mortality rates when spirotetramat 11.2 ppm and isocycloceram 2.0, 6.0, and 20.0 ppm were used in combination.
  • the figures in parentheses indicate the mortality rates predicted by the Colby formula.
  • the mortality rates were 93.9%, 77.1%, and 87.8%, respectively.
  • This result showed a synergistic effect compared to the mortality rates predicted by the Colby formula (61.2%, 72.3%, and 83.1%, respectively).
  • Example 4 A pest control composition containing spirotetramat as the first component and ciproflanilide as the second component was prepared.
  • the pest control composition was used against first instar larvae of cotton aphid, a pest belonging to the order Hemiptera and the family Aphididae, by spraying the cucumber leaf disk and insect body. The results after 3 days of treatment are shown in Tables 17 to 21.
  • Table 17 below shows the mortality rate when ciproflanilide is used alone.
  • the predicted mortality rate for each concentration combination can be calculated using the Colby formula described above.
  • Table 18 shows the mortality rate of insects when spirotetramat 0.336 ppm and ciproflanilide 0.250, 0.750, and 2.500 ppm were used in combination.
  • the values in parentheses indicate the mortality rate predicted by the Colby formula.
  • the mortality rates were 6.1%, 24.2%, and 60.7%, respectively, three days after treatment. This result showed a synergistic effect with respect to the mortality rates predicted by the Colby formula (3.5%, 6.8%, and 34.5%, respectively).
  • Table 19 below shows the mortality rates when spirotetramat was used in combination with 1.12 ppm and ciprofuranilide at 0.075, 0.750, and 2.500 ppm.
  • the figures in parentheses indicate the mortality rates predicted by the Colby formula.
  • the mortality rates were 3.3%, 61.5%, and 78.2%, respectively. This result showed a synergistic effect compared to the mortality rates predicted by the Colby formula (0.0%, 3.4%, and 32.1%, respectively).
  • Table 21 shows the mortality rates when spirotetramat 11.2 ppm and ciprofuranilide 0.250, 0.750, and 2.500 ppm were used in combination.
  • the figures in parentheses indicate the mortality rates predicted by the Colby formula.
  • the mortality rates were 81.0%, 79.5%, and 100%, respectively. This result showed a synergistic effect compared to the mortality rates predicted by the Colby formula (56.5%, 58.0%, and 70.5%, respectively).
  • Example 5 A pest control composition containing spirotetramat as the first component and broflanilide as the second component was prepared.
  • the pest control composition was used in a cabbage leaf immersion test against third-instar larvae of Spodoptera litura, a pest belonging to the order Lepidoptera and family Noctuidae. The results after 1 day, 2 days, and 3 days of treatment are shown in Tables 22 to 28.
  • Table 22 below shows the mortality rate when spirotetramat is used alone.
  • Table 23 below shows the mortality rate when broflanilide is used alone.
  • the predicted mortality rates for each concentration combination can be calculated using the Colby formula described above.
  • Table 24 shows the mortality rate when spirotetramat 1.12 ppm and broflanilide 0.25 ppm are used in combination.
  • the mortality rate of the combined use of spirotetramat 1.12 ppm and broflanilide 0.25 ppm was 70.0% 1 day after treatment and 65.0% 2 days after treatment. This result showed a synergistic effect compared to the mortality rate predicted from the mortality rate of spirotetramat 1.12 ppm alone (0.0% 1 day after treatment, 0.0% 2 days after treatment) and the mortality rate of broflanilide 0.25 ppm alone (45.0% 1 day after treatment, 30.0% 2 days after treatment).
  • Table 25 shows the mortality rate when spirotetramat 0.0336 ppm and broflanilide 0.075 and 0.25 ppm were used in combination.
  • the figures in parentheses indicate the mortality rate predicted by the Colby formula.
  • the mortality rates were 29.2% and 100.0%, respectively. This result showed a synergistic effect compared to the mortality rates predicted by the Colby formula (20.8% and 95.8%, respectively).
  • Table 26 shows the mortality rate when spirotetramat 0.112 ppm and broflanilide 0.075 ppm were used in combination.
  • the figures in parentheses indicate the mortality rate predicted by the Colby formula. As a result, three days after treatment, the mortality rate was 29.2%. This result showed a synergistic effect compared to the mortality rate predicted by the Colby formula (20.8%).
  • Table 27 shows the mortality rate when spirotetramat 0.336 ppm and broflanilide 0.0075 and 0.25 ppm were used in combination.
  • the figures in parentheses indicate the mortality rate predicted by the Colby formula.
  • the mortality rates were 4.2% and 100.0%, respectively. This result showed a synergistic effect compared to the mortality rates predicted by the Colby formula (0% and 95.8%, respectively).
  • Table 28 below shows the mortality rate when spirotetramat 1.12 ppm and broflanilide 0.25 ppm were used in combination.
  • the figures in parentheses indicate the mortality rate predicted by the Colby formula. As a result, three days after treatment, the mortality rate was 100.0%. This result showed a synergistic effect compared to the mortality rate predicted by the Colby formula (95.8%).
  • Table 29 below shows the mortality rates when spirotetramat 3.36 ppm and broflanilide 0.025, 0.075, and 0.25 ppm were used in combination.
  • the figures in parentheses indicate the mortality rates predicted by the Colby formula. As a result, three days after treatment, the mortality rates were 12.5%, 29.2%, and 100.0%. These results showed a synergistic effect compared to the mortality rates predicted by the Colby formula (4.2%, 20.8%, and 95.8%, respectively).
  • Example 6 A pest control composition containing spirotetramat as a first component and ciproflanilide as a second component was prepared.
  • the pest control composition was used in a cabbage leaf immersion test against third-instar larvae of Spodoptera litura, a pest belonging to the order Lepidoptera and family Noctuidae. The results after 1 day and 4 days of treatment are shown in Tables 30 to 38.
  • Table 30 below shows the mortality rate when spirotetramat is used alone.
  • Table 31 below shows the mortality rate when ciproflanilide is used alone.
  • the predicted mortality rates for each concentration combination can be calculated using the Colby formula described above.
  • Table 32 shows the mortality rate when spirotetramat 0.0336 ppm and ciproflanilide 0.025 ppm were used in combination.
  • the figures in parentheses indicate the mortality rate predicted by the Colby formula. As a result, 4 days after treatment, the mortality rate was 60.0%. This result showed a synergistic effect compared to the mortality rate predicted by the Colby formula (41.7%).
  • Table 33 shows the mortality rate from the combined use of spirotetramat 0.0112 ppm and ciprofuranilide 0.025 ppm. As a result, the mortality rates were 12.5% and 50.0% one day and four days after treatment, respectively. This result showed a synergistic effect compared to the mortality rates predicted by the Colby formula (4.2% and 41.7%, respectively).
  • Table 34 shows the mortality rate when spirotetramat 0.336 ppm and ciproflanilide 0.025 ppm were used in combination. As a result, the mortality rates were 33.3% and 88.0% one day and four days after treatment, respectively. This result showed a synergistic effect compared to the mortality rates predicted by the Colby formula (4.2% and 41.7%, respectively).
  • Table 35 shows the mortality rate when spirotetramat 0.336 ppm and ciproflanilide 0.075 ppm were used in combination.
  • the figures in parentheses show the mortality rate predicted by the Colby formula. As a result, one day after treatment, the mortality rate was 87.5%. This result showed a synergistic effect compared to the mortality rate predicted by the Colby formula (83.3%).
  • Table 36 shows the mortality rate when spirotetramat 1.12 ppm and ciproflanilide 0.025 ppm were used in combination. As a result, the mortality rates were 37.5% and 79.2% one day and four days after treatment, respectively. This result showed a synergistic effect compared to the mortality rates predicted by the Colby formula (4.2% and 41.7%, respectively).
  • Table 37 shows the mortality rate when spirotetramat 3.36 ppm and ciprofuranilide 0.025 ppm were used in combination. As a result, the mortality rates were 16.7% and 50.0% one day and four days after treatment, respectively. This result showed a synergistic effect compared to the mortality rates predicted by the Colby formula (4.2% and 41.7%, respectively).
  • Table 38 shows the mortality rate when spirotetramat 3.36 ppm and ciprofuranilide 0.075 ppm were used in combination.
  • the figures in parentheses indicate the mortality rate predicted by the Colby formula. As a result, one day after treatment, the mortality rate was 100.0%. This result showed a synergistic effect with respect to the mortality rate predicted by the Colby formula (83.3%).
  • Example 7 A pest control composition containing spirotetramat as a first component and fluxametamide as a second component was prepared.
  • the pest control composition was used against third-instar larvae of Spodoptera litura, a pest belonging to the order Lepidoptera and family Noctuidae, in a cabbage leaf immersion test. The results after 4 days of treatment are shown in Tables 39 to 44.
  • Table 39 below shows the mortality rate when spirotetramat is used alone.
  • Table 40 below shows the mortality rate when fluxametamide was used alone.
  • Table 42 shows the mortality rate when spirotetramat 0.0112 ppm and fluxametamide 0.015 ppm were used in combination.
  • the figures in parentheses indicate the mortality rate predicted by the Colby formula. As a result, 4 days after treatment, the mortality rate was 54.2%. This result showed a synergistic effect compared to the mortality rate predicted by the Colby formula (4.0%).
  • Table 43 shows the mortality rate when spirotetramat 0.112 ppm and fluxametamide 0.015 ppm were used in combination.
  • the figures in parentheses indicate the mortality rate predicted by the Colby formula. As a result, 4 days after treatment, the mortality rate was 35.0%. This result showed a synergistic effect compared to the mortality rate predicted by the Colby formula (4.0%).
  • Table 44 shows the mortality rate when spirotetramat 0.336 ppm and fluxamethamide 0.015 ppm were used in combination.
  • the figures in parentheses indicate the mortality rate predicted by the Colby formula. As a result, 4 days after treatment, the mortality rate was 45.8%. This result showed a synergistic effect compared to the mortality rate predicted by the Colby formula (4.0%).
  • Example 8 A pest control composition containing spirotetramat as a first component and isocycloceram as a second component was prepared.
  • the pest control composition was used against third-instar larvae of Spodoptera litura, a pest belonging to the order Lepidoptera and family Noctuidae, in a cabbage leaf immersion test. The results after 3 days and 6 days of treatment are shown in Tables 45 to 56.
  • Table 45 below shows the mortality rate when spirotetramat is used alone.
  • Table 46 below shows the mortality rate when Isocycloceram is used alone.
  • the predicted mortality rates for each concentration combination can be calculated using the Colby formula described above.
  • Table 47 shows the mortality rate when spirotetramat 1.12 ppm and isocycloceram 12 and 40 ppm are used in combination.
  • the figures in parentheses show the mortality rate predicted by the Colby formula.
  • the mortality rates were 65.0% and 92.0%, respectively. This result showed a synergistic effect compared to the mortality rates predicted by the Colby formula (55.0% and 91.0%, respectively).
  • Table 48 shows the mortality rate when spirotetramat 1.12 ppm and isocycloceram 0.4 and 1.2 ppm were used in combination.
  • the figures in parentheses show the mortality rate predicted by the Colby formula.
  • 6 days after treatment the mortality rates were 83.3% and 87.5%, respectively. This result showed a synergistic effect compared to the mortality rates predicted by the Colby formula (75.0% and 83.3%, respectively).
  • Tables 49 and 50 below show the mortality rates 3 and 6 days after treatment with a combination of 3.36 ppm spirotetramat and 0.4 and 1.2 ppm isocycloceram.
  • the figures in parentheses indicate the mortality rates predicted by the Colby formula. As a result, 3 days after treatment, the mortality rates were 11.0% and 38.0%, respectively. 6 days after treatment, the mortality rates were 87.5% and 87.5%, respectively. These results showed a synergistic effect against the mortality rates predicted by the Colby formula (0.0% and 0.0%, respectively, 3 days after treatment, and 75.0% and 83.3%, respectively, 6 days after treatment).
  • Table 51 shows the mortality rates three days after treatment when spirotetramat was used in combination with 3.36 ppm and isocycloceram at 4, 12 and 40 ppm.
  • the figures in parentheses indicate the mortality rates predicted by the Colby formula.
  • the mortality rates were 53.0%, 75.0% and 100.0%, respectively. This result showed a synergistic effect against the mortality rates predicted by the Colby formula (29.0%, 55.0% and 91.0%, respectively).
  • Table 52 below shows the mortality rates 3 and 6 days after treatment with a combination of 11.2 ppm spirotetramat and 1.2 ppm isocycloceram. As a result, the mortality rates were 14.0% and 91.7%, respectively, 3 and 6 days after treatment. This result showed a synergistic effect compared to the mortality rates predicted by the Colby formula (0.0% and 83.3%, respectively).
  • Table 53 shows the mortality rate when spirotetramat 11.2 ppm and isocycloceram 4 ppm were used in combination.
  • the figures in parentheses show the mortality rate predicted by the Colby formula. As a result, three days after treatment, the mortality rate was 45.0%. This result showed a synergistic effect compared to the mortality rate predicted by the Colby formula (29.0%).
  • Table 54 shows the mortality rate 6 days after treatment when spirotetramat 33.6 ppm and isocycloceram 0.4 and 1.2 ppm were used in combination.
  • the figures in parentheses indicate the mortality rate predicted by the Colby formula.
  • 6 days after treatment the mortality rates were 95.8% and 95.8%, respectively. This result showed a synergistic effect against the mortality rates predicted by the Colby formula (75.0% and 83.3%, respectively).
  • Table 55 shows the mortality rate three days after treatment when spirotetramat 33.6 ppm and isocycloceram 12 and 40 ppm were used in combination.
  • the figures in parentheses indicate the mortality rate predicted by the Colby formula.
  • the mortality rates were 60.0% and 96.0%, respectively. This result showed a synergistic effect against the mortality rates predicted by the Colby formula (55.0% and 91.0%, respectively).
  • Table 56 shows the mortality rate 6 days after treatment when spirotetramat was used in combination at 112 ppm, and isocycloceram at 0.4 and 1.2 ppm.
  • the figures in parentheses indicate the mortality rate predicted by the Colby formula.
  • 6 days after treatment the mortality rates were 95.8% and 95.8%, respectively. This result showed a synergistic effect compared to the mortality rates predicted by the Colby formula (75.0% and 83.3%, respectively).
  • Example 9 A pest control composition was prepared containing spirotetramat as the first component and broflanilide as the second component.
  • the pest control composition was used against eggs of Tetranychus urticae, a pest belonging to the family Tetranychidae, order Acarina, by using a kidney leaf disk.
  • the results after 7 days of treatment are shown in Tables 57 to 59.
  • the tables show the total of egg killing rate + insect mortality rate (total of egg killing rate and insect mortality rate) for each combination of the specified concentrations.
  • Table 57 shows the total egg killing rate and insect death rate when spirotetramat is used alone.
  • the predicted total egg killing rate + insect mortality rate for each concentration combination can be calculated using the Colby formula described above.
  • Table 59 shows the total egg killing rate + insect mortality rate after 7 days of treatment when spirotetramat was used in combination at 0.336 ppm and broflanilide at 0.025, 0.075, and 0.25 ppm.
  • the figures in parentheses indicate the total egg killing rate + insect mortality rate predicted by the Colby formula.
  • the total egg killing rate + insect mortality rate was 55.1%, 73.6%, and 55.9%, respectively. This result showed a synergistic effect with respect to the total egg killing rate + insect mortality rate predicted by the Colby formula (49.9%, 49.2%, and 53.6%, respectively).
  • Example 10 A pest control composition containing spirotetramat as a first component and isocycloceram as a second component was prepared.
  • the pest control composition was used against eggs of Tetranychus urticae, a pest belonging to the family Tetranychidae, order Acarina, by using a kidney leaf disk.
  • the results after 8 days of treatment are shown in Tables 60 to 64.
  • Table 61 shows the total egg killing rate and insect death rate when Isocycloceram is used alone.
  • Table 62 shows the total egg killing rate + insect mortality rate when spirotetramat 0.00336 ppm and isocycloceram 0.006, 0.03 and 0.06 ppm are used in combination.
  • the figures in parentheses show the total egg killing rate + insect mortality rate predicted by the Colby formula.
  • the total egg killing rate + insect mortality rate was 5.1%, 8.1% and 97.9%, respectively.
  • This result showed a synergistic effect against the total egg killing rate + insect mortality rate predicted by the Colby formula (3.5%, 6.1% and 95.7%, respectively).
  • Example 11 A pest control composition containing spirotetramat as a first component and fluxametamide as a second component was prepared.
  • the pest control composition was used against eggs of Tetranychus urticae, a pest belonging to the family Tetranychidae, order Acarina, by using a kidney leaf disk.
  • the results after 8 days of treatment are shown in Tables 65 to 67.
  • Table 67 shows the total egg killing rate + insect mortality rate when spirotetramat 0.0112 ppm and fluxamethamide 0.5 ppm are used in combination.
  • the figures in parentheses show the total egg killing rate + insect mortality rate predicted by the Colby formula.
  • the total egg killing rate + insect mortality rate was 70.1%. This result showed a synergistic effect against the insect mortality rate predicted by the Colby formula (34.0%).
  • Example 12 A pest control composition containing spirotetramat as a first component and ciproflanilide as a second component was prepared.
  • the pest control composition was used against eggs of Tetranychus urticae, a pest belonging to the family Tetranychidae, order Acarina, by using a kidney leaf disk.
  • the results after 11 days of treatment are shown in Tables 68 to 70.
  • spiromesifen was used instead of spirotetramat to prepare a pest control composition containing spiromesifen and broflanilide.
  • the pest control composition was applied to eggs of Tetranychus urticae, a pest belonging to the family Tetranychidae, order Acarina, using a kidney leaf disk.
  • the results after 7 days of treatment are shown in Tables 71 to 73.
  • the table shows the total egg killing rate + insect death rate for each given concentration combination.
  • Table 71 shows the total egg killing rate and insect mortality rate when spiromesifen is used alone.
  • the predicted total egg killing rate + insect mortality rate for each concentration combination can be calculated using the Colby formula described above.
  • the total egg killing rate + insect mortality rate of the combined use of spiromesifen 0.15 ppm and broflanilide 0.025 ppm was 15.8% 7 days after treatment. This result showed no synergistic effect compared to the total egg killing rate + insect mortality rate (19.3% after 7 days treatment) predicted from the total egg killing rate + insect mortality rate of spiromesifen 0.15 ppm alone (14.4% after 7 days treatment) and the total egg killing rate + insect mortality rate of broflanilide 0.025 ppm alone (5.7% after 7 days treatment).
  • Table 73 shows the combined egg killing rate and insect mortality rate for the combined use of spiromesifen at 0.45 ppm and broflanilide at 0.075 ppm.
  • the total egg killing rate + insect mortality rate of the combined use of spiromesifen 0.45 ppm and broflanilide 0.075 ppm was 81.6% 7 days after treatment. This result showed no synergistic effect compared to the total egg killing rate + insect mortality rate predicted from the total egg killing rate + insect mortality rate of spiromesifen 0.45 ppm alone (100.0%) and the total egg killing rate + insect mortality rate of broflanilide 0.075 ppm alone (4.3%).
  • Example 13 A pest control composition containing spirotetramat as a first component and broflanilide as a second component was prepared.
  • the pest control composition was used against the third instar larvae of the diamondback moth, which is a pest belonging to the Lepidoptera and Noctuidae families, in a cabbage leaf immersion test. The results after 3 days of treatment are shown in Tables 74 to 79.
  • Table 74 shows the mortality rate when spirotetramat is used alone.
  • Table 75 below shows the mortality rate when broflanilide is used alone.
  • the predicted mortality rate for each concentration combination can be calculated using the Colby formula described above.
  • Table 77 shows the mortality rate from the combined use of spirotetramat 0.0112 ppm and broflanilide 0.0075 ppm.
  • the figures in parentheses indicate the mortality rate predicted by the Colby formula.
  • the mortality rate was 4.2%. This result showed a synergistic effect compared to the mortality rate predicted by the Colby formula (0.0%).
  • Table 78 shows the mortality rate when spirotetramat 0.0336 ppm and broflanilide 0.0075 and 0.025 ppm were used in combination.
  • the figures in parentheses indicate the mortality rate predicted by the Colby formula. As a result, three days after treatment, the mortality rates were 28.6% and 100.0%. This result showed a synergistic effect compared to the mortality rates predicted by the Colby formula (0.0 and 80.0%, respectively).
  • Table 79 shows the mortality rate when spirotetramat 0.336 ppm and broflanilide 0.025 ppm were used in combination.
  • the figures in parentheses indicate the mortality rate predicted by the Colby formula. As a result, three days after treatment, the mortality rate was 91.6%. This result showed a synergistic effect compared to the mortality rate predicted by the Colby formula (80.0%).
  • Example 14 A pest control composition containing spirotetramat as a first component and ciproflanilide as a second component was prepared.
  • the pest control composition was used against the third instar larvae of the diamondback moth, which is a pest belonging to the Lepidoptera and Noctuidae families, in a cabbage leaf immersion test. The results after 6 days of treatment are shown in Tables 80 to 85.
  • Table 80 below shows the mortality rate when spirotetramat is used alone.
  • Table 81 shows the mortality rate when ciproflanilide is used alone.
  • the predicted mortality rates for each concentration combination can be calculated using the Colby formula described above.
  • Table 82 shows the mortality rate when spirotetramat 0.0112 ppm and ciproflanilide 0.025 ppm were used in combination.
  • the figures in parentheses indicate the mortality rate predicted by the Colby formula. As a result, 6 days after treatment, the mortality rate was 87.0%. This result showed a synergistic effect compared to the mortality rate predicted by the Colby formula (64.5%).
  • Table 83 shows the mortality rate when spirotetramat 0.0336 ppm and ciproflanilide 0.025 ppm were used in combination.
  • the figures in parentheses show the mortality rate predicted by the Colby formula. As a result, 6 days after treatment, the mortality rate was 78.3%. This result showed a synergistic effect compared to the mortality rate predicted by the Colby formula (64.5%).
  • Table 84 shows the mortality rate when spirotetramat 0.112 ppm and ciproflanilide 0.0075 and 0.025 ppm were used in combination.
  • the figures in parentheses indicate the mortality rate predicted by the Colby formula. As a result, 6 days after treatment, the mortality rates were 47.0% and 91.6%. This result showed a synergistic effect compared to the mortality rates predicted by the Colby formula (16.1% and 62.7%, respectively).
  • Table 85 shows the mortality rate when spirotetramat 0.336 ppm and ciprofuranilide 0.0075 and 0.025 ppm were used in combination.
  • the figures in parentheses show the mortality rate predicted by the Colby formula. As a result, 6 days after treatment, the mortality rates were 17.3% and 73.9%. This result showed a synergistic effect compared to the mortality rates predicted by the Colby formula (12.1% and 61.0%, respectively).
  • the predicted mortality rate for each concentration combination can be calculated using the Colby formula described above.
  • Table 88 shows the mortality rate when spirotetramat is used alone.
  • Table 89 shows the mortality rate when broflanilide is used alone.
  • the predicted mortality rates for each concentration combination can be calculated using the Colby formula described above.
  • Table 90 shows the mortality rates when spirotetramat 0.336 ppm and broflanilide 0.025, 0.075, 0.25, 0.75, and 2.5 ppm were used in combination.
  • the figures in parentheses indicate the mortality rates predicted by the Colby formula. As a result, 7 days after treatment, the mortality rates were 32.9, 31.8, 44.9, 27.6, and 31.4%, respectively. These results showed a synergistic effect with respect to the mortality rates predicted by the Colby formula (18.6, 27.5, 18.6, 18.6, and 18.6%, respectively).
  • Table 91 shows the mortality rates when spirotetramat 1.12 ppm and broflanilide 0.025, 0.075, 0.25, 0.75, and 2.5 ppm were used in combination.
  • the figures in parentheses indicate the mortality rates predicted by the Colby formula. As a result, 7 days after treatment, the mortality rates were 28.6, 26.6, 37.5, 21.2, and 23.0%, respectively. These results showed a synergistic effect with respect to the mortality rates predicted by the Colby formula (15.5, 24.7, 15.5, 15.5, and 15.5%, respectively).
  • Table 92 shows the mortality rates when spirotetramat 3.36 ppm and broflanilide 0.025, 0.075, 0.25, 0.75, and 2.5 ppm were used in combination.
  • the figures in parentheses indicate the mortality rates predicted by the Colby formula. As a result, 7 days after treatment, the mortality rates were 65.6, 73.9, 66.4, 85.7, and 76.2%, respectively. These results showed a synergistic effect with respect to the mortality rates predicted by the Colby formula (52.7, 57.9, 52.7, 52.7, and 52.7%, respectively).
  • the pest control composition of the present invention and the method for controlling plant diseases or plant pests using the composition have useful control effects due to the novel combination, and therefore are useful as pesticides.

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  • Pest Control & Pesticides (AREA)
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Abstract

L'invention concerne une composition de lutte contre les organismes nuisibles qui comprend un spirotétramate, et au moins un composé choisi parmi un composé à base de phénylpyrazole, un composé à base d'isoxazoline et un composé à base de méta-diamide.
PCT/JP2024/043955 2023-12-15 2024-12-12 Composition de lutte contre les organismes nuisibles, et procédé de lutte contre les maladies ou parasites des plantes mettant en œuvre cette composition Pending WO2025127094A1 (fr)

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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010505753A (ja) * 2006-09-30 2010-02-25 バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト 懸濁濃縮製剤
JP2013133307A (ja) * 2011-12-27 2013-07-08 Sumitomo Chemical Co Ltd 有害節足動物防除組成物及び有害節足動物の防除方法
CN111053086A (zh) * 2019-12-24 2020-04-24 安徽辉隆集团银山药业有限责任公司 一种杀虫组合物
JP2020083756A (ja) * 2018-11-14 2020-06-04 三井化学アグロ株式会社 殺虫組成物および有害生物の防除方法
JP2020522552A (ja) * 2017-06-09 2020-07-30 ユーピーエル リミテッドUpl Limited 新規な農薬の組み合わせ
JP2022001566A (ja) * 2020-06-19 2022-01-06 日産化学株式会社 害虫防除組成物および害虫の防除方法
WO2023112988A1 (fr) * 2021-12-16 2023-06-22 住友化学株式会社 Procédé de lutte contre des arthropodes nuisibles
WO2023209733A1 (fr) * 2022-04-26 2023-11-02 Rajdhani Petrochemicals Private Limited Composition de fluxamétamide et son procédé de préparation

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010505753A (ja) * 2006-09-30 2010-02-25 バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト 懸濁濃縮製剤
JP2013133307A (ja) * 2011-12-27 2013-07-08 Sumitomo Chemical Co Ltd 有害節足動物防除組成物及び有害節足動物の防除方法
JP2020522552A (ja) * 2017-06-09 2020-07-30 ユーピーエル リミテッドUpl Limited 新規な農薬の組み合わせ
JP2020083756A (ja) * 2018-11-14 2020-06-04 三井化学アグロ株式会社 殺虫組成物および有害生物の防除方法
CN111053086A (zh) * 2019-12-24 2020-04-24 安徽辉隆集团银山药业有限责任公司 一种杀虫组合物
JP2022001566A (ja) * 2020-06-19 2022-01-06 日産化学株式会社 害虫防除組成物および害虫の防除方法
WO2023112988A1 (fr) * 2021-12-16 2023-06-22 住友化学株式会社 Procédé de lutte contre des arthropodes nuisibles
WO2023209733A1 (fr) * 2022-04-26 2023-11-02 Rajdhani Petrochemicals Private Limited Composition de fluxamétamide et son procédé de préparation

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