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WO2025107053A1 - Barrière protégeant les plaies chirurgicales et non chirurgicales et isolant les tissus - Google Patents

Barrière protégeant les plaies chirurgicales et non chirurgicales et isolant les tissus Download PDF

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Publication number
WO2025107053A1
WO2025107053A1 PCT/BR2024/050535 BR2024050535W WO2025107053A1 WO 2025107053 A1 WO2025107053 A1 WO 2025107053A1 BR 2024050535 W BR2024050535 W BR 2024050535W WO 2025107053 A1 WO2025107053 A1 WO 2025107053A1
Authority
WO
WIPO (PCT)
Prior art keywords
surgical
barrier
wounds
protecting
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/BR2024/050535
Other languages
English (en)
Portuguese (pt)
Inventor
Gabriela MEIRA SALOMÃO AMBRIZZI
Munir Salomão
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from BR102023024438-6A external-priority patent/BR102023024438B1/pt
Application filed by Individual filed Critical Individual
Publication of WO2025107053A1 publication Critical patent/WO2025107053A1/fr
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00089—Wound bandages
    • A61F2013/00217—Wound bandages not adhering to the wound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00365—Plasters use
    • A61F2013/00387—Plasters use skin protection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00361—Plasters
    • A61F2013/00795—Plasters special helping devices
    • A61F2013/00825—Plasters special helping devices protection of wound surround

Definitions

  • the present invention belongs to the tissue engineering or regenerative medicine sector, and refers, more specifically, to a barrier consisting of a biocompatible polypropylene film, to protect surgical wounds or otherwise, avoiding direct contact with the external environment, ensuring healing without interference from irritants that may delay and even contaminate the surgical wound, preventing the installation of infectious processes.
  • polypropylene screens are widely used to reinforce the abdominal wall in cases of hernias.
  • the screens are perforated, which differs from the product revealed here, which consists of a 100% waterproof polypropylene film, i.e., it does not present porosities.
  • the material used by this patent is an effective solution for covering and protecting surgical and non-surgical wounds, being easy to handle, highly biocompatible, safe and low cost.
  • the barrier When used to protect and isolate the tissues where it is inserted, the barrier meets all the requirements required to be used in such a way that it protects and isolates the tissues, thus preventing the adhesion of one tissue in relation to another or even when used on grafts, in their most varied forms or when placed on biomaterials. It is also indicated for closing bucco-sinusal communications where there is no presence of acute processes. It is biocompatible, is easy to handle clinically, isolates the compromised tissues, preventing the penetration of food remains (due to its impermeability).
  • the barrier now revealed, on the contrary, protects, isolates and brings comfort to the patient, due to its flexibility and thickness, not causing such inconveniences.
  • the barrier When exposed to the oral environment, it maintains its integrity, acting as an impermeable, non-resorbable mechanical barrier.
  • Another novelty is that it can also be used to promote tissue separation, when used on autogenous, allogeneic or xenogeneic bone grafts, or even particulate or block biomaterials. It is also indicated for use in cases of grafts associated with medullary blood, aspirated blood or in decorticated areas, thus ensuring the containment of stem cells.
  • polypropylene film as a barrier for wound protection, for application as a temporary dressing, is not known.
  • the film is used for guided bone regeneration in dentistry, which does not rule out the fact that it also protects the surgical wound, however, this is not the purpose of use in the case of guided bone regeneration.
  • polypropylene There is only this reference to the use of polypropylene.
  • the present invention has the advantage of being able to be used both for covering and protecting wounds, as well as as a tissue insulator, preventing adhesion between them, after all it is easy to handle and can be customized according to each application.
  • Figure 1 represents the use of the invention in dressings held in position by bandages, in various parts of the body;
  • Figure 2 represents the use of the invention covering and protecting surgery performed on the palate and fixed with sutures
  • Figure 3 represents the use of the invention on allogenic bone block grafts
  • Figure 4 represents photographs of a finger with a severed phalanx, in which polypropylene film was used as a temporary dressing and protective material for the wound.
  • the present invention consists of a biaxially oriented polypropylene film, biocompatible and biotolerable with a thickness ranging from 17 to 80 micrometers, sterilized by gamma radiation or ethylene oxide.
  • the fact that it is sterile is important because it will not carry to the site any type of microorganism that could come into contact with the injured tissue, causing an infectious process.
  • polypropylene mesh is already widely used in medicine.
  • the advantage of using a film and not a polypropylene mesh is that the film, because it is waterproof and does not contain porosities (unlike the mesh) or spaces between the weaves, can easily be a temporary substitute for covering fabrics in any part of the human or animal body where this is indicated, for example: skin, connective tissue, burns, bedsores.
  • Another advantage is that, because the material is biocompatible, it can be associated with the use of grafts or biomaterials, when necessary.
  • the polypropylene film being biocompatible, also offers the advantage of being able to remain submerged even after the tissue has been repaired. This is another advantage of this invention and even if it has to be removed, the film does not adhere to the repaired tissue, making it easier to remove, unlike meshes that are sutured to the tissue and are not removed.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)

Abstract

La présente invention relève du secteur de l'ingénierie tissulaire ou de la médecine régénérative, et concerne plus particulièrement une barrière constituée par un film de polypropylène biocompatible, pour protéger les plaies chirurgicales ou non chirurgicales, évitant un contact direct avec le milieu extérieur, assurant une cicatrisation sans interférence d'agents irritants susceptibles de retarder le processus, voire de contaminer la plaie chirurgicale, et empêchant l'apparition de processus infectieux.
PCT/BR2024/050535 2023-11-23 2024-11-22 Barrière protégeant les plaies chirurgicales et non chirurgicales et isolant les tissus Pending WO2025107053A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BR1020230244386 2023-11-23
BR102023024438-6A BR102023024438B1 (pt) 2023-11-23 Barreira protetora de feridas cirúrgicas e não cirúrgicas e isoladora de tecidos

Publications (1)

Publication Number Publication Date
WO2025107053A1 true WO2025107053A1 (fr) 2025-05-30

Family

ID=90575390

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BR2024/050535 Pending WO2025107053A1 (fr) 2023-11-23 2024-11-22 Barrière protégeant les plaies chirurgicales et non chirurgicales et isolant les tissus

Country Status (1)

Country Link
WO (1) WO2025107053A1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6240968B1 (en) * 1996-08-14 2001-06-05 Rtc, Inc. Membranes suitable for medical use
WO2010057280A1 (fr) * 2008-11-19 2010-05-27 Salomao Munir Barrière pour régénération osseuse guidée
BRPI0810606A2 (pt) * 2007-04-27 2014-10-21 Endo Pharmaceuticals Solutions Agentes de liberação de dispositivo de implante e métodos de uso dos mesmos

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6240968B1 (en) * 1996-08-14 2001-06-05 Rtc, Inc. Membranes suitable for medical use
BRPI0810606A2 (pt) * 2007-04-27 2014-10-21 Endo Pharmaceuticals Solutions Agentes de liberação de dispositivo de implante e métodos de uso dos mesmos
WO2010057280A1 (fr) * 2008-11-19 2010-05-27 Salomao Munir Barrière pour régénération osseuse guidée

Also Published As

Publication number Publication date
BR102023024438A2 (pt) 2024-02-20

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