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WO2025153301A1 - Composition de soin buccal - Google Patents

Composition de soin buccal

Info

Publication number
WO2025153301A1
WO2025153301A1 PCT/EP2024/087648 EP2024087648W WO2025153301A1 WO 2025153301 A1 WO2025153301 A1 WO 2025153301A1 EP 2024087648 W EP2024087648 W EP 2024087648W WO 2025153301 A1 WO2025153301 A1 WO 2025153301A1
Authority
WO
WIPO (PCT)
Prior art keywords
composition according
percent
composition
zinc
toothpaste composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/EP2024/087648
Other languages
English (en)
Inventor
Sembian CHANDRASEKARAN
Roberto GUAGLIARDO
Robert Edward Marriott
Anisha Malay PUNJANI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Unilever Global IP Ltd
Unilever IP Holdings BV
Conopco Inc
Original Assignee
Unilever Global IP Ltd
Unilever IP Holdings BV
Conopco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unilever Global IP Ltd, Unilever IP Holdings BV, Conopco Inc filed Critical Unilever Global IP Ltd
Publication of WO2025153301A1 publication Critical patent/WO2025153301A1/fr
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20—Halogens; Compounds thereof
    • A61K8/21—Fluorides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25—Silicon; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/27—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/731—Cellulose; Quaternized cellulose derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Definitions

  • Zinc salts have been used in some oral care compounds for a number of years.
  • compositions comprising zinc salts that do not dis-colour.
  • the present invention relates to a toothpaste composition
  • a toothpaste composition comprising: i) an abrasive ii) a humectant comprising sorbitol and glycerol in which the weight ratio of sorbitol to glycerol is 1 :1 to 1:10.
  • a zinc salt selected from zinc chloride, a zinc sulphate or mixtures thereof
  • an amino acid in which the weight ratio of zinc salt to the amino acid is greater than 1:1.
  • oral care composition refers to a composition that is delivered to the oral surfaces.
  • the composition may be a product which, during the normal course of usage, is not for the purpose of systemic administration or intentionally swallowed but is rather retained in the oral cavity for a time sufficient to contact substantially all of the dental surfaces and/or oral tissues for the purposes of oral activity.
  • the composition of the invention in the form of a toothpaste.
  • toothpaste denotes an oral composition which is used to clean the surfaces of the oral cavity. Such a composition is not intentionally swallowed for purposes of systemic administration of therapeutic agents, but is applied to the oral cavity, used to treat the oral cavity and then expectorated. Typically such a composition is used in conjunction with a cleaning implement such as a toothbrush, usually by applying it to the bristles of the toothbrush and then brushing the accessible surfaces of the oral cavity.
  • the amount of remineralising phosphate source(s) (e.g. trisodium phosphate and sodium dihydrogen phosphate) in the composition of this invention typically ranges from 2 to 15%, preferably from 4 to 10% by total weight remineralising phosphate source based on the total weight of the oral care composition.
  • Any orally acceptable natural or synthetic flavorant can be used, including without limitation essential oils and various flavoring aldehydes, esters, alcohols, and similar materials, tea flavors, vanillin, sage, marjoram, parsley oil, spearmint oil, cinnamon oil, oil of Wintergreen, peppermint oil, clove oil, bay oil, anise oil, eucalyptus oil, citrus oils, fruit oils, sassafras and essences including those derived from lemon, orange, lime, grapefruit, apricot, banana, grape, apple, strawberry, cherry, pineapple, etc., bean-and nut-derived flavors such as coffee, cocoa, cola, peanut, almond, etc., adsorbed and encapsulated flavorants and the like.
  • One or more flavorants are optionally present in a total amount of from about 0.01 wt. percent to about 5 wt. percent, for example, from about 0.03 wt. percent to about 2.5 wt. percent, optionally about 0.05 wt. percent to about 1.5 wt. percent, further optionally about 0.1 wt. percent to about 0.3 wt. percent and in some embodiments in various embodiments from about 0.01 wt. percent to about 1 wt. percent, from about 0.05 to about 2 percent, from about 0.1 percent to about 2.5 percent, and from about 0.1 to about 0.5 percent by total weight of the composition.
  • compositions were prepared as in table 1.
  • the Examples show how Examples according to the invention have less dis-colouration than the comparative Examples comprising a humectant system with higher levels of sorbitol.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cosmetics (AREA)

Abstract

L'invention concerne une composition de dentifrice comprenant : i) un abrasif ; ii) un sel de zinc choisi parmi le chlorure de zinc, un sulfate de zinc ou des mélanges de ceux-ci ; iii) un humectant comprenant du sorbitol et du glycérol, le rapport pondéral du sorbitol au glycérol étant compris entre 1:1 et 1:10 ; iv) un acide aminé ; le rapport en poids entre le sel de zinc et l'acide aminé étant supérieur à 1:1.
PCT/EP2024/087648 2024-01-19 2024-12-19 Composition de soin buccal Pending WO2025153301A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP24152826 2024-01-19
EP24152826.4 2024-01-19

Publications (1)

Publication Number Publication Date
WO2025153301A1 true WO2025153301A1 (fr) 2025-07-24

Family

ID=89662070

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2024/087648 Pending WO2025153301A1 (fr) 2024-01-19 2024-12-19 Composition de soin buccal

Country Status (1)

Country Link
WO (1) WO2025153301A1 (fr)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2052978A (en) 1979-06-20 1981-02-04 Unilever Ltd Oral compositions containing zinc salts
US4416867A (en) * 1979-06-20 1983-11-22 Lever Brothers Company Oral compositions
EP0236070A2 (fr) 1986-02-28 1987-09-09 Unilever Plc Silices
EP0251146A2 (fr) * 1986-06-27 1988-01-07 Blendax GmbH Composition d'hygiène buccale
EP0740932A1 (fr) 1995-05-03 1996-11-06 Unilever N.V. Dentifrice sous forme de gel optiquement clair
JP2003137755A (ja) * 2001-11-02 2003-05-14 Lion Corp 口腔用組成物
CN106236612B (zh) * 2016-08-27 2020-06-26 广东罗浮山国药股份有限公司 一种牙膏及其制备方法

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2052978A (en) 1979-06-20 1981-02-04 Unilever Ltd Oral compositions containing zinc salts
US4416867A (en) * 1979-06-20 1983-11-22 Lever Brothers Company Oral compositions
EP0236070A2 (fr) 1986-02-28 1987-09-09 Unilever Plc Silices
EP0251146A2 (fr) * 1986-06-27 1988-01-07 Blendax GmbH Composition d'hygiène buccale
EP0740932A1 (fr) 1995-05-03 1996-11-06 Unilever N.V. Dentifrice sous forme de gel optiquement clair
JP2003137755A (ja) * 2001-11-02 2003-05-14 Lion Corp 口腔用組成物
CN106236612B (zh) * 2016-08-27 2020-06-26 广东罗浮山国药股份有限公司 一种牙膏及其制备方法

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