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WO2025152019A1 - Dispositif de test d'analyte de fluide corporel - Google Patents

Dispositif de test d'analyte de fluide corporel

Info

Publication number
WO2025152019A1
WO2025152019A1 PCT/CN2024/072438 CN2024072438W WO2025152019A1 WO 2025152019 A1 WO2025152019 A1 WO 2025152019A1 CN 2024072438 W CN2024072438 W CN 2024072438W WO 2025152019 A1 WO2025152019 A1 WO 2025152019A1
Authority
WO
WIPO (PCT)
Prior art keywords
bottom shell
detection device
body fluid
analyte detection
transmitter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/CN2024/072438
Other languages
English (en)
Chinese (zh)
Inventor
杨翠军
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medtrum Technologies Inc
Original Assignee
Medtrum Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtrum Technologies Inc filed Critical Medtrum Technologies Inc
Priority to PCT/CN2024/072438 priority Critical patent/WO2025152019A1/fr
Publication of WO2025152019A1 publication Critical patent/WO2025152019A1/fr
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase

Definitions

  • pancreas in a normal person's body can automatically monitor the glucose content in the human blood and automatically secrete the required insulin/glucagon.
  • the pancreas of diabetic patients has abnormal function and cannot normally secrete the insulin required by the human body. Therefore, diabetes is a metabolic disease caused by abnormal pancreatic function in the human body, and diabetes is a lifelong disease.
  • medical technology cannot cure diabetes, and can only control the occurrence and development of diabetes and its complications by stabilizing blood sugar.
  • CGM continuous glucose monitoring
  • the embodiment of the present invention discloses a body fluid analyte detection device, in which an emitter and a bottom shell are releasably connected. After the user installs the disposable bottom shell on the skin surface, the reusable emitter is assembled on the bottom shell to form a complete analyte detection device. When the user replaces the analyte detection device, the user only needs to apply force to one side of the bottom shell to bend the bottom shell to failure, and then the emitter can be separated from the bottom shell. Then, the bottom shell can be removed from the skin to complete the disassembly. A crease groove is provided on the bottom shell to facilitate the bending of the bottom shell.
  • the structure is simple, and the installation and disassembly operations are convenient, which saves time and effort and enhances the user experience.
  • the present invention discloses a body fluid analyte detection device, comprising: a bottom shell; a transmitter, used to establish a communication connection with an external device; a battery, used to provide electric energy for the body fluid analyte detection device; a sensor and a conductive adhesive strip mounted on the bottom shell, the sensor comprising an internal part and an external part, the internal part being used to penetrate subcutaneously to detect body fluid analyte parameter information, when the transmitter is mounted on the bottom shell, the external part is electrically connected to the transmitter through the conductive adhesive strip to transmit the analyte parameter information to the transmitter; and an adhesive tape, the adhesive tape Used to stick the bottom shell to the skin surface; wherein a crease groove is provided on the bottom shell, the crease groove is thinner relative to the bottom surface of the bottom shell, the crease groove includes a straight portion and a curved portion, and when the bottom shell and the transmitter are separated, the bottom shell bends along the crease groove and fails.
  • the curved portions are disposed at both ends of the straight portion.
  • the curved portion and/or the straight portion is a semi-hollow structure.
  • the conductive rubber strip is a rectangular parallelepiped structure.
  • the conductive rubber strip includes a conductive area and an insulating area which are spaced apart in the longitudinal direction.
  • the transmitter includes a first electrical connection area, and the first electrical connection area and the external part are electrically connected to the conductive area on the conductive rubber strip respectively.
  • the first electrical connection area and the external portion are electrically connected to the conductive area on the structural surface adjacent to or opposite to the conductive rubber strip, respectively.
  • At least one non-electrically connected structural surface of the conductive rubber strip is covered with an insulating material.
  • the bottom shell includes at least one first engaging portion
  • the transmitter includes at least one second engaging portion.
  • the first engaging portion engages with the second engaging portion.
  • the first engaging portion is decoupled from the second engaging portion.
  • the first engaging portion is distributed on the arc-surface side wall of the bottom shell.
  • the bottom case includes a battery cavity, and the battery is disposed in the battery cavity.
  • the battery cavity includes a cavity shell, and the cavity shell is used as an outer shell of the battery.
  • FIG7a is a schematic diagram of the structure of a conductive rubber strip according to an embodiment of the present invention.
  • the third engaging portions 1012 are symmetrically distributed on the side wall of the bottom housing 101 .
  • the bottom shell 101 is provided with a first snap-fitting portion 1011 and a third snap-fitting portion 1012
  • the transmitter 102 is provided with a second snap-fitting portion 1021 and a fourth snap-fitting portion 1022, and the position, shape and number of the second snap-fitting portion 1021 and the fourth snap-fitting portion 1022 are respectively adapted to the first snap-fitting portion 1011 and the third snap-fitting portion 1012.
  • the transmitter 102 can be stably fixed on the bottom shell 101 by the first engaging portion 1011 and the third engaging portion 1012 respectively engaging with the second engaging portion 1021 and the fourth engaging portion 1022. Since the transmitter 102 is reusable, when the user replaces a new analyte detection device 10, the transmitter 102 needs to be removed from the bottom shell 101. For this purpose, a solution is designed in which the bottom shell 101 can be bent and fail. When the bottom shell 101 is bent and fails, the engagement of the first engaging portion 1011 with the second engaging portion 1021 or/and the engagement of the third engaging portion 1012 with the fourth engaging portion 1022 are decoupled, thereby separating the transmitter 102 and the bottom shell 101. See below for details.
  • the bottom shell 101 in order to allow the bottom shell 101 to bend and fail, the bottom shell 101 needs to be made of flexible materials, such as PE or PP plastic.
  • the bottom shell 101 needs to be attached to the user's skin surface, such as the arm or stomach, during use.
  • the user's skin surface is constantly moving or bending during daily activities, and the overly soft bottom shell 101 will also bend, which will cause the first clamping part 1011 and the second clamping part 1021 or/and the third clamping part 1012 and the fourth clamping part 1022 to be decoupled with a certain probability, causing the transmitter 102 and the bottom shell 101 to become loose. Based on this, the bottom shell 101 cannot be too soft.
  • the bottom surface at the crease groove 1016 is relatively reduced by 0.01-0.7 mm, or the bottom surface at the crease groove 1016 is half hollow (no bottom shell material is provided at the hollow part, and the bottom surface thickness is 0 mm here), that is, the bottom surfaces on both sides of the crease groove 1016 are intermittently connected by the bottom shell 101 material, or the crease groove 1016 is not provided on the bottom surface of the bottom shell 101, but the bottom surface of the bottom shell 101 is only provided with a half-hollow structure, and the bottom surfaces of the bottom shells on both sides are connected, which can also facilitate users to bend the bottom shell 101.
  • the curved portion 10162 has a portion that is at a certain angle to the x-axis, which can increase the bending strength of the crease groove 1016, increase the rigidity design redundancy of the bottom shell 101, make the crease groove 1016 not easy to bend during daily use, and improve the connection stability between the transmitter 102 and the bottom shell 101.
  • the fold groove 1016 can also be used in conjunction with the third engaging portion 1012 and the fourth engaging portion 1022 to complete the engagement and separation of the bottom shell 101 and the transmitter 102, as described in detail below.
  • the bottom surface of the straight portion 10161 or the curved portion 10162 may also be half hollow, that is, the bottom surfaces on both sides of the straight portion 10161 or the curved portion 10162 are discontinuously connected by the material of the bottom shell 101, and the unconnected parts are completely removed, which can reduce the overall weight of the analyte detection device 10.
  • the crease groove 1016 is a straight groove or a straight and curved combination groove, both ends thereof correspond to the third engaging portion 1012 and the fourth engaging portion 1022 .
  • the bottom shell 101 includes a fixing portion and a force-applying portion.
  • the fixing portion and the force-applying portion are relative concepts, which will be described in detail below.
  • failure is a conventional concept in the field of engineering materials. After failure, the material loses its original function and the failed part cannot be restored again. Since the third engaging portion 1012 is a part of the bottom shell 101, the failure of the bottom shell 101 includes the failure of the bottom surface, side wall or third engaging portion 1012 of the bottom shell 101. Therefore, the failure modes of the bottom shell 101 include the breakage of the bottom shell 101, the bending deformation of the bottom shell 101, and the breakage of the third engaging portion 1012. Obviously, after the bottom shell 101 fails, the bottom shell 101 loses the function and role of engaging the transmitter 102.
  • the method of fixing the fixing part includes clamping, supporting, etc., which is not specifically limited here, as long as the conditions for fixing the fixing part are met.
  • the fold groove 1016 divides the bottom shell into two sides, one side is used as the fixing part, and the other side is used as the force applying part.
  • the fixing part and the force applying part can be interchangeable.
  • the process of separating the bottom shell 101 and the transmitter 102 is as follows: fix the fixing part with a finger, and use another finger to apply a force F to the force-applying part in one direction, so that the bottom shell 101 is bent or curved, and the fourth clamping part 1022 is disengaged from the clamping of the third clamping part 1012 and decoupled, so that the transmitter 102 is separated from the bottom shell 101.
  • the bottom shell 101 is bent or curved along the crease groove 1016. The cooperation of the crease groove and the third and fourth clamping parts enables the transmitter and the bottom shell to be better separated.
  • the process of separating the bottom shell 101 and the transmitter 102 is as follows: fix the fixing portion with a finger, and use another finger to apply a force F to the force-applying portion in one direction to invalidate the third clamping portion 1012, thereby separating the third clamping portion 1012 and the fourth clamping portion 1022, so that the transmitter 102 is separated from the bottom shell 101.
  • the battery cavity 1013 serves as a force-applying portion
  • the transmitter 102 serves as a fixing portion.
  • the user fixes the transmitter 102 with one finger, and applies a force F to the battery cavity 1013 with another finger, so that the battery cavity 1013 bends along the direction of curve a, and the fourth engaging portion 1022 has a movement tendency in the direction of curve d relative to the battery cavity 1013.
  • the bottom shell 101 bends and deforms, and the bottom shell 101 no longer presses against the fourth engaging portion 1022, and the transmitter 102 moves along the direction of curve b relative to the battery cavity 1013.
  • the force-applying part and the fixing part are relative.
  • the transmitter 102 serves as the force-applying part and the battery cavity 1013 serves as the fixing part, and the disassembly process is the same.
  • the cavity cover 10132 is connected to the cavity shell 10131 by bonding, snapping, welding, etc. to be fixed on the battery cavity 1013. It is understandable that the cavity cover 10132 is connected to the cavity shell 10131 by bonding, snapping, welding, etc. before production. The connection with the cavity shell 10131 can be releasable, or it can be in a separated state. After the battery is installed, the cavity cover 10132 is fixedly connected to the cavity shell 10131, and the cavity cover 10132 and the cavity shell 10131 can be completely sealed. The cavity cover 10132 cannot be removed again, so as to prevent the cavity cover 10132 from loosening and external dirt from entering the battery cavity 1013.
  • the battery is an independent button battery, and the battery is accommodated in the battery cavity 1013.
  • the positive electrode and the negative electrode of the battery are electrically connected to the elastic conductor 1014 respectively, and the other end of the elastic conductor 1014 is electrically connected to the second electrical connection area 1024 of the transmitter 102.
  • the elastic conductor 1014 serves as a conductive carrier, so that the battery can provide electrical energy to the transmitter 102.
  • the second electrical connection area 1024 is compatible with the elastic conductor 1014, and the number of the second electrical connection area 1024 is the same.
  • the second electrical connection area 1024 contacts and compresses the elastic conductor 1014.
  • the elastic conductor 1014 in the compressed state can be in closer contact with the second electrical connection area 1024.
  • the elastic force of the elastic conductor 1014 can also help separate the transmitter 102 from the bottom shell 101.
  • the second electrical connection region 1024 is a metal contact.
  • the battery cavity 1013 itself serves as a battery body to provide electrical energy to the analyte detection device 10, as shown in FIG. 6 for details.
  • Screening of electrolytic manganese dioxide, conductive agent and binder can be done by screen or airflow classifier, and electrolytic manganese dioxide particles with a particle size less than 200um are selected, placed in a quartz boat, and heat treated in a sintering furnace at a temperature of 200°C for 4 hours.
  • the purpose of this step is to make the electrolytic manganese dioxide lose some of its bound water, shift the X-ray diffraction peak, reduce the interplanar spacing, and enhance the Mn-O bonding force, thereby enhancing the discharge capacity of the electrolytic manganese dioxide.
  • the binder may be one or more of PVDF (polyvinylidene fluoride), polytetrafluoroethylene, and sodium polyacrylate.
  • PVDF polyvinylidene fluoride
  • polytetrafluoroethylene polytetrafluoroethylene
  • sodium polyacrylate sodium polyacrylate
  • the thickness of the positive electrode sheet can be controlled to ensure that the electrode sheet has a relatively complete conductive network under the premise of a high compaction density, so as to meet the working requirements of high current pulse discharge.
  • the negative electrode plate 10136 is mainly made of lithium-based material.
  • the positive electrode plate 10135 may also be a lithium-containing compound such as lithium manganese oxide, lithium cobalt oxide, lithium iron phosphate, etc., and the corresponding negative electrode plate 10136 is graphite.
  • the material of the diaphragm 10133 is PE (polyethylene) or PP (polypropylene), which can be a single layer of PE or PP or three layers of PE or PP.
  • one end A of the conductive sheet 10138 is fixedly connected to the positive electrode sheet 10135 or the negative electrode sheet 10136, and the other end B of the conductive sheet 10138 passes through the electrolyte isolation layer 10137 and the cavity shell 10131, and is electrically connected to the elastic conductor 1014.
  • the end A is fixedly connected to the positive electrode sheet 10135 or the negative electrode sheet 10136 by solder or solder paste.
  • the conductive sheet 10138 connected to the positive electrode plate 10135 is made of aluminum, and the conductive sheet 10138 connected to the negative electrode plate 10136 is made of nickel or nickel-plated copper.
  • the material of the cavity shell 10131 is generally plastic, such as PE (polyethylene), PP (polypropylene) or PC (polycarbonate), which is easily corroded by the electrolyte 10134. Therefore, it is necessary to set an electrolyte isolation layer 10137 inside the cavity shell 10131.
  • PE polyethylene
  • PP polypropylene
  • PC polycarbonate
  • the electrolyte isolation layer 10137 is TPE (butyl rubber) or PET (polyethylene terephthalate).
  • TPE is a thermoplastic elastomer material with strong processability.
  • the PET material itself is used as a container for the electrolyte and can effectively isolate the corrosion of the cavity shell by the electrolyte.
  • the electrolyte isolation layer 10137 can be a thin film coated on the inner side of the cavity shell 10131 by a deposition method or a solution method, or it can be a separate closed shell.
  • the electrolyte isolation layer 10137 is a thin film with a thickness of 300-500um. If the thickness of the electrolyte isolation layer 10137 is too small, the membrane will be soaked and softened by the electrolyte, which will cause the membrane to age after a long time. If the thickness is too large, it will occupy the internal space of the chamber. In a more preferred embodiment of the present invention, the thickness of the electrolyte isolation layer 10137 is 400um.
  • the cavity shell 10131 is made of a material resistant to corrosion by the electrolyte 10134, such as PFA (polytetrafluoroethylene) or FEP (fluoroethylene propylene), the electrolyte isolation layer 10137 can be omitted, the volume of the electrolyte 10134 can be increased, and the battery energy storage can be improved.
  • PFA polytetrafluoroethylene
  • FEP fluoroethylene propylene
  • a sensor module is further provided on the bottom shell 101 .
  • the sensor module includes an elastic sealing ring 1031 , a sensor 1032 , and a conductive rubber strip 1033 .
  • the sensor 1032 includes an internal part 10321 and an external part 10322 .
  • the elastic sealing ring 1031 is an annular structural member, and the external part 10322 and the conductive rubber strip 1033 are both located in the inner circle of the elastic sealing ring 1031.
  • the lower end surface of the elastic sealing ring 1031 contacts the bottom surface of the bottom shell 101, and the upper end surface contacts the shell of the transmitter 102, forming a completely closed space in the inner circle of the elastic sealing ring 1031, and the external part 10322 and the conductive rubber strip 1033 are in this closed space.
  • the closed space of the elastic sealing ring 1031 can prevent dirt such as water droplets, metal chips, and blood from entering, avoiding contamination of the external part 10322 and the conductive rubber strip 1033, and affecting the detection signal.
  • Figure 7a is a schematic diagram of the structure of the conductive rubber strip according to an embodiment of the present invention.
  • Figure 7b is a schematic diagram of the structure of a conductive rubber strip according to an embodiment of the present invention where one structural surface is sealed.
  • Figures 7c to 7f are schematic diagrams of the structure of the sensor and the conductive rubber strip assembled on the bottom shell according to an embodiment of the present invention.
  • Figure 7g is a schematic diagram of the structure of the conductive area of the conductive rubber strip according to an embodiment of the present invention where the conductive area is sealed.
  • the conductive rubber strip 1033 is a three-dimensional structure having multiple structural surfaces, such as a rectangular parallelepiped structure.
  • the conductive rubber strip 1033 has conductive areas and insulating areas that are spaced apart in the longitudinal length, and both the conductive areas and the insulating areas run through the lateral direction of the conductive rubber strip 1033, where the lateral direction is perpendicular to the longitudinal direction.
  • the four side structural surfaces 1033a, 1033b, 1033c, and 1033d of the conductive rubber strip 1033 all have conductive areas and insulating areas, and it can be understood that the corresponding conductive areas on the four side structural surfaces 1033a, 1033b, 1033c, and 1033d are electrically connected.
  • the conductive area and the insulating area are distributed at intervals.
  • the insulating area can separate two adjacent conductive areas.
  • the insulating area has good insulating properties, which can prevent crosstalk between electrical signals of two adjacent conductive areas and ensure the stability of the detection signal.
  • the conductive adhesive strip 1033 is used to electrically connect the sensor 1032 and the transmitter 102.
  • the transmitter includes a first electrical connection area 1023, and the first electrical connection area 1023 includes at least At least two metal contacts 10231 are provided on the external part 10322 of the sensor 1032 (not shown in the figure), and each metal contact 10231 is in contact with a different conductive area on a single structural surface of the conductive rubber strip 1033, and at the same time, the corresponding conductive areas of the above-mentioned conductive areas on the same, adjacent or opposite structural surfaces are in contact with the pins, thereby realizing the electrical connection between the pins and the metal contacts 10231.
  • the detection signal of the sensor 1032 can be transmitted to the transmitter 102 through the conductive rubber strip 1033, and the transmitter 102 can also transmit the control signal to the sensor 1032 through the conductive rubber strip 1033.
  • the number of metal contacts 10231 is the same as the number of pins.
  • the metal contact 10231 establishes an electrical connection with the external part 10322 through the relative structural surfaces of the conductive rubber strip 1033, i.e., 1033a, 1033c or 1033b, 1033d, forming a stacked structure of the external part 10322-conductive rubber strip 1033-metal contact 10231.
  • the external part 10322 is laid flat on the bottom surface of the bottom shell 101 in a parallel state, as shown in Figure 7c.
  • the metal contact 10231 and the external part 10322 establish electrical connection through adjacent structural surfaces of the conductive rubber strip 1033, such as the external part 10322 is electrically connected to the side structural surface 1033c of the conductive rubber strip 1033, and the metal contact 10231 is electrically connected to the upper structural surface 1033d.
  • the external part 10322 is laid flat on the bottom surface of the bottom shell 101 in a vertical state, as shown in Figure 7d.
  • the above embodiment is for illustration only, and other adjacent structural surfaces can also realize the electrical connection function.
  • the electrical connection of adjacent structural surfaces can reduce the overall thickness, which is conducive to the miniaturization design of the analyte detection device 10.
  • a pit 1017 may be further provided on the bottom shell 101, and the external part 10322 or the conductive rubber strip 1033 may be placed in the pit 1017.
  • the external part 10322 or the conductive rubber strip 1033 may be placed in the pit 1017, and the external part 10322 or the conductive rubber strip 1033 may be fixed by interference fitting the external part 10322 or the conductive rubber strip 1033 with the pit 1017, thereby improving the assembly stability of the sensor 1032 or the conductive rubber strip 1033.
  • the external portion 10322 is electrically connected to the side structural surface 1033 c of the conductive rubber strip 1033
  • the first electrical connection area 1023 of the transmitter 102 is electrically connected to the upper structural surface 1033 d of the conductive rubber strip 1033 .
  • the conductive area is continuous with the conductive area on the used structural surface. If the conductive area is short-circuited by dirt, it will also cause the conductive area on the used structural surface to short-circuit, affecting the stability of the detection signal. Therefore, it is possible to consider sealing the conductive area on the unused structural surface to prevent it from being short-circuited by dirt. For example, with reference to FIG.
  • the side joint of the external part 10322 and the conductive rubber strip 1033 The first electrical connection area 1023 of the emitter 102 is electrically connected to the upper structural surface 1033d of the conductive rubber strip 1033.
  • the side structural surface 1033a and the lower structural surface 1033b are not used, and an insulating material can be coated or pasted on the side structural surface 1033a and/or the lower structural surface 1033b to prevent the conductive areas on these two structural surfaces from being short-circuited by dirt.
  • only 1033a is easily contaminated, so only 1033a can be coated or pasted, so as to prevent the conductive area from being short-circuited by dirt and avoid wasting insulating materials.
  • the external part 10322 is electrically connected to the lower structural surface 1033b of the conductive rubber strip 1033, and the first electrical connection area 1023 of the transmitter 102 is electrically connected to the upper structural surface 1033d of the conductive rubber strip 1033.
  • the side structural surfaces 1033a and 1033c are not used, and insulating material can be coated or pasted on the side structural surfaces 1033a and/or 1033c.
  • insulating material is coated or pasted on both the side structural surfaces 1033a and 1033c to prevent the conductive areas on these two structural surfaces from being short-circuited due to dirt.
  • the insulating material may be one or more of rubber, silicone, polyethylene, glass fiber, epoxy resin, and insulating varnish, as long as good insulating properties can be achieved.
  • the thickness of the insulating material is 1 to 1000 um, and preferably, the thickness of the insulating material is 10 to 100 um.
  • the insulating material may only cover the conductive area of the conductive rubber strip 1033, and may also achieve the function of insulating the non-electrically connected structural surface.
  • FIG. 7g is a top view of the conductive rubber strip 1033.
  • the first electrical connection area 1023 of the transmitter 102 is electrically connected to the upper structural surface 1033d of the conductive rubber strip 1033.
  • the conductive area on the upper structural surface 1033d that is not electrically connected to the first electrical connection area 1023 may also be contaminated by dirt and cause a short circuit. Based on this situation, the conductive area that is not electrically connected to the first electrical connection area 1023 may also be covered with an insulating material, and the insulating material is distributed at intervals on the upper structural surface 1033d.
  • the external part 10322 is electrically connected to the side structural surface 1033c of the conductive rubber strip 1033.
  • the conductive area on the side structural surface 1033c that is not electrically connected to the external part 10322 may also be contaminated by dirt and cause a short circuit. Therefore, the conductive area on the side structural surface 1033c that is not electrically connected to the external part 10322 may also be covered with an insulating material, and the insulating material is distributed at intervals on the side structural surface 1033c.
  • the insulating material is covered on two adjacent conductive areas in a continuous form, and at the same time covers the insulating area between the two adjacent conductive areas.
  • the insulating material is covered on two adjacent conductive areas in an interval form, and does not cover the insulating area between the two adjacent conductive areas.
  • the conductive rubber strip 1033 is covered with insulating material on the structural surface that is not electrically connected to other components, which can better avoid short circuit caused by dirt contamination and improve the stability of the detection signal.
  • the external portion 10322 is bent or folded relative to the internal portion 10321, and the internal portion 10321 is perpendicular or approximately perpendicular to the bottom shell 101 and passes through the bottom shell 101 to facilitate penetration into the user's subcutaneous tissue.
  • the external part 10322 is fixed to the bottom shell 101 through a sensor base.
  • the sensor base and the bottom shell 101 are releasably connected. Before installation, the sensor base is separated from the bottom shell 101. During installation, the sensor base is assembled to the bottom shell 101.
  • the external portion 10322 is directly laid flat on the bottom surface of the bottom shell 101, eliminating the sensor base structure, making the internal structure of the analyte detection device 10 more compact and conducive to miniaturized design.
  • the present invention discloses a body fluid analyte detection device, in which the transmitter and the bottom shell are releasably connected.
  • the reusable transmitter is assembled on the bottom shell to form a complete analyte detection device.
  • the user replaces the analyte detection device, the user only needs to apply force to one side of the bottom shell to bend the bottom shell to failure, and then the transmitter can be separated from the bottom shell. Then, the bottom shell can be removed from the skin to complete the disassembly.
  • a crease groove is provided on the bottom shell to facilitate the bending of the bottom shell.

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Abstract

La présente invention concerne un dispositif de test d'analyte de fluide corporel. Un émetteur est en liaison libérable avec une coque inférieure. Après avoir fixé une coque inférieure jetable à la surface de la peau, un utilisateur assemble un émetteur réutilisable sur la coque inférieure, de manière à former un dispositif complet de test d'analyte. Lors du remplacement du dispositif de test d'analyte, l'utilisateur a seulement besoin d'appliquer une force sur un côté de la coque inférieure pour provoquer la rupture par flexion de celle-ci et permettre ainsi de séparer le transmetteur de la coque inférieure, puis de retirer la coque inférieure de la peau pour terminer le processus de démontage. Une rainure est formée dans la coque inférieure afin de faciliter la flexion de celle-ci. Le dispositif de test d'analyte de fluide corporel a une structure simple et est facile à assembler et à démonter, ce qui permet de gagner du temps et de réduire la main-d'œuvre, tout en améliorant l'expérience utilisateur.
PCT/CN2024/072438 2024-01-16 2024-01-16 Dispositif de test d'analyte de fluide corporel Pending WO2025152019A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/CN2024/072438 WO2025152019A1 (fr) 2024-01-16 2024-01-16 Dispositif de test d'analyte de fluide corporel

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2024/072438 WO2025152019A1 (fr) 2024-01-16 2024-01-16 Dispositif de test d'analyte de fluide corporel

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WO2025152019A1 true WO2025152019A1 (fr) 2025-07-24

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Citations (7)

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