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WO2025146819A1 - Dispositif de commande de trajectoire de particules et procédé de commande de trajectoire de particules - Google Patents

Dispositif de commande de trajectoire de particules et procédé de commande de trajectoire de particules Download PDF

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Publication number
WO2025146819A1
WO2025146819A1 PCT/JP2024/046443 JP2024046443W WO2025146819A1 WO 2025146819 A1 WO2025146819 A1 WO 2025146819A1 JP 2024046443 W JP2024046443 W JP 2024046443W WO 2025146819 A1 WO2025146819 A1 WO 2025146819A1
Authority
WO
WIPO (PCT)
Prior art keywords
vibration
flow path
trajectory control
particle trajectory
particle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/JP2024/046443
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English (en)
Japanese (ja)
Inventor
直友 鳥取
裕輝 福永
臣耶 佐久間
陽子 山西
健 早川
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyushu University NUC
Chuo University
Original Assignee
Kyushu University NUC
Chuo University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyushu University NUC, Chuo University filed Critical Kyushu University NUC
Publication of WO2025146819A1 publication Critical patent/WO2025146819A1/fr
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03B—SEPARATING SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS
    • B03B5/00—Washing granular, powdered or lumpy materials; Wet separating
    • B03B5/02—Washing granular, powdered or lumpy materials; Wet separating using shaken, pulsated or stirred beds as the principal means of separation
    • B03B5/04—Washing granular, powdered or lumpy materials; Wet separating using shaken, pulsated or stirred beds as the principal means of separation on shaking tables

Definitions

  • the present disclosure has been made in consideration of the above problems, and aims to provide a particle trajectory control device and a particle trajectory control method that can change the separation diameter.
  • this disclosure provides the following means.
  • the particle trajectory control device includes a flow path device and a vibration device.
  • the flow path device has a flow path with a plurality of pillars arranged therein.
  • the vibration device is configured to apply vibrations to the flow path device.
  • the particle trajectory control method includes a first step of flowing a liquid containing a plurality of particles through a flow path in which a plurality of pillars are arranged, and a second step of applying vibration to the flow path.
  • the particle trajectory control device and particle trajectory control method disclosed herein can change the separation diameter.
  • FIG. 2 is a schematic diagram of a particle trajectory control device according to the first embodiment.
  • FIG. 2 is a plan view of the flow path device according to the first embodiment.
  • 5A to 5C are schematic diagrams illustrating the movement of particles when no vibration is applied to the flow channel device according to the first embodiment.
  • 5A to 5C are schematic diagrams illustrating the movement of particles when vibration is applied to the flow channel device according to the first embodiment.
  • FIG. 11 is a schematic diagram of a particle trajectory control device according to a second embodiment.
  • FIG. 11 is a plan view of a flow path device according to a second embodiment.
  • FIG. 13 is a schematic diagram of a particle trajectory control device according to a third embodiment. 1 shows the flow of particles around a pillar of the flow channel device of Example 1.
  • 4A to 4C are diagrams illustrating movement of particles in the flow channel device of Example 1.
  • 1 is a demonstration result of particle separation of Example 1.
  • 13 is a demonstration result of particle separation of Example 2.
  • 13 is a demonstration result of particle separation of Example 3.
  • 13 is a demonstration result of particle separation of Example 4.
  • the plane on which the flow path device extends is the XY plane, one of which is the X direction, and the direction perpendicular to the X direction is the Y direction.
  • the X direction is, for example, the longitudinal direction of the flow path in the flow path device, and is the direction from the inlet to the outlet of the flow path.
  • the X direction is an example of a first direction.
  • the Y direction is an example of a second direction.
  • the Z direction is a direction perpendicular to the XY plane, and is, for example, the thickness direction of the flow path device.
  • the Z direction is an example of a third direction.
  • First embodiment 1 is a schematic diagram of a particle trajectory control device 500 according to a first embodiment.
  • the particle trajectory control device 500 includes, for example, a flow channel device 100, a vibration device 200, and a signal generator 300.
  • FIG. 2 is a plan view of a flow path device 100 according to the first embodiment.
  • the flow path device 100 includes, for example, a flow path element 1 and a substrate 2.
  • the substrate 2 is, for example, bonded to the flow path element 1.
  • the substrate 2 may be made of any material, such as glass or plastic.
  • the substrate 2 and the flow path element 1 may be bonded together to form a flow path.
  • the substrate 2 is not limited to being flat, and may have a pattern formed thereon.
  • the pattern of the substrate 2 and the pattern of the flow path element 1 may be combined to form a flow path.
  • the presence of the substrate 2 makes it easier to apply the vibrations generated by the vibration device 200 to the flow path element 1.
  • the substrate 2 is not essential.
  • the flow path element 1 has a flow path 10 inside.
  • the flow path element 1 may have a groove formed on one surface, and may be bonded to the substrate 2 to form the flow path 10.
  • the flow path element 1 may be made of, for example, silicon, glass, polymer resin, etc. It is preferable that the flow path element 1 is made of, for example, polydimethylsiloxane (PDMS).
  • PDMS polydimethylsiloxane
  • the flow path 10 has an inlet 11, an outlet 12, and a particle trajectory control unit 13.
  • the inlet 11 is an input part for fluid to the flow path 10.
  • the number of inlets 11 is not limited to one. There may be multiple inlets 11.
  • the outlet 12 is an output part of the fluid from the flow path 10.
  • the number of outlets 12 is not limited to two. For example, if particles are classified into three categories, large, medium, and small, it is preferable to have three outlets 12.
  • the number of outlets 12 can be any number depending on the design.
  • the particle trajectory control unit 13 is a part that connects the inlet 11 and the outlet 12. When a fluid flows through the particle trajectory control unit 13, the particles contained in the fluid are separated according to particle size. The flow direction of the particles contained in the fluid may also be controlled by flowing the fluid through the particle trajectory control unit 13. A plurality of pillars 14 are formed in the particle trajectory control unit 13.
  • the length of the particle trajectory control unit 13 in the X direction is, for example, 1 ⁇ m or more and 1 m or less.
  • the width of the particle trajectory control unit 13 in the Y direction is, for example, 1 ⁇ m or more and 1 m or less.
  • the multiple pillars 14 are arranged at regular intervals in both the X and Y directions.
  • a row of pillars 14 aligned in the Y direction are arranged at regular intervals in the X direction.
  • the pillar rows are not limited to being aligned in the Y direction, and may be aligned in a direction tilted from the Y direction.
  • pillars 14 adjacent in the X direction do not need to be at the same position in the Y direction, but may be offset in the Y direction.
  • the line segment connecting pillars aligned in the X direction may extend in the X direction, may extend in a direction tilted from the X direction, or may be zigzag.
  • pillars 14 adjacent in the Y direction do not need to be at the same position in the X direction, but may be offset in the X direction.
  • the line segment connecting pillars aligned in the Y direction may extend in the Y direction, may extend in a direction tilted from the Y direction, or may be zigzag.
  • the spacing between each pillar 14 is not particularly important.
  • the spacing between the pillars 14 can be freely designed according to the separation diameter.
  • the shortest distance between each pillar 14 is, for example, 1 nm or more and 10 mm or less, and preferably 1 nm or more and 1 mm or less.
  • each pillar 14 is not particularly important.
  • the diameter of the pillar 14 can be freely designed.
  • the diameter of the pillar 14 is, for example, 1 nm or more and 10 mm or less.
  • each pillar 14 is not particularly important.
  • the height of the pillar 14 can be freely designed.
  • the height of the pillar 14 is, for example, 1 nm or more and 10 mm or less.
  • Each of the multiple pillars 14 is, for example, a cylinder.
  • the pillars 14 are not necessarily limited to cylinders.
  • the pillars 14 may be pyramidal or frustum.
  • the planar shape of the pillars 14 is not limited to a circle.
  • the planar shape of the pillars 14 may be elliptical, oval, or polygonal.
  • the axial direction of the pillars 14 may be in the Z direction or inclined from the Z direction.
  • the pillars 14 may be connected to the top and bottom surfaces of the flow channel 10, may be connected only to the top surface of the flow channel 10, or may be connected only to the bottom surface of the flow channel 10.
  • the vibration device 200 is configured to apply vibrations to the flow path device 100.
  • the vibration device 200 applies vibrations having components in any of the X-direction, Y-direction, and Z-direction to the flow path device 100.
  • the direction in which the vibration device 200 vibrates the flow path device 100 is not particularly important.
  • the vibration device 200 may vibrate the flow path device 100 in the X direction, the Y direction, or the Z direction, or a combination of these vibrations.
  • the vibration device 200 may vibrate the flow path device 100 in the X direction and the Y direction so as to draw a circle when viewed from the Z direction.
  • the first oscillator 201 contacts, for example, the first side of the flow path device 100.
  • the first oscillator 201 applies vibration to the flow path device 100 in at least the X direction.
  • the first oscillator 201 shown in FIG. 1 contacts the substrate 2, but may also directly contact the flow path element 1.
  • the second oscillator 202 contacts, for example, the second side of the flow path device 100.
  • the second oscillator 202 applies vibrations to the flow path device 100 in at least the Y direction.
  • the second oscillator 202 shown in FIG. 1 contacts the substrate 2, but may also directly contact the flow path element 1.
  • the vibration device 200 shown in FIG. 1 can apply any vibration in the XY plane by adjusting the amplitude and phase of the first oscillator 201 and the second oscillator 202.
  • the amplitude or phase of the first oscillator 201 may be different from the amplitude or phase of the second oscillator 202.
  • by shifting the vibration period of the first oscillator 201 and the vibration period of the second oscillator 202 by half a period it is possible to apply a vibration that rotates in a circular shape when viewed from the Z direction to the flow path device 100.
  • the vibration device 200 may also have a third vibrator on the bottom or top surface of the flow path device 100.
  • the third vibrator applies vibration to the flow path device 100 in at least the Z direction.

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  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

La présente invention concerne un dispositif de commande de trajectoire de particules comprenant un dispositif de trajet d'écoulement et un dispositif de vibration. Le dispositif de trajet d'écoulement a un trajet d'écoulement dans lequel une pluralité de piliers sont agencés. Le dispositif de vibration est conçu de façon à pouvoir appliquer une vibration au dispositif de trajet d'écoulement.
PCT/JP2024/046443 2024-01-05 2024-12-27 Dispositif de commande de trajectoire de particules et procédé de commande de trajectoire de particules Pending WO2025146819A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202463617776P 2024-01-05 2024-01-05
US63/617,776 2024-01-05

Publications (1)

Publication Number Publication Date
WO2025146819A1 true WO2025146819A1 (fr) 2025-07-10

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PCT/JP2024/046443 Pending WO2025146819A1 (fr) 2024-01-05 2024-12-27 Dispositif de commande de trajectoire de particules et procédé de commande de trajectoire de particules

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WO (1) WO2025146819A1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016006642A1 (fr) * 2014-07-08 2016-01-14 国立大学法人東北大学 Dispositif de manipulation de particules et procédé de classement de particules à l'aide de ce dispositif
JP2018030057A (ja) * 2016-08-22 2018-03-01 国立大学法人東京工業大学 微粒子分離デバイスおよび微粒子の分離方法
JP2019208418A (ja) * 2018-06-01 2019-12-12 学校法人 中央大学 粒子分離用装置及び粒子分離方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016006642A1 (fr) * 2014-07-08 2016-01-14 国立大学法人東北大学 Dispositif de manipulation de particules et procédé de classement de particules à l'aide de ce dispositif
JP2018030057A (ja) * 2016-08-22 2018-03-01 国立大学法人東京工業大学 微粒子分離デバイスおよび微粒子の分離方法
JP2019208418A (ja) * 2018-06-01 2019-12-12 学校法人 中央大学 粒子分離用装置及び粒子分離方法

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