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WO2025091220A2 - Composition sous forme d'émulsion huile dans l'eau - Google Patents

Composition sous forme d'émulsion huile dans l'eau Download PDF

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Publication number
WO2025091220A2
WO2025091220A2 PCT/CN2023/128349 CN2023128349W WO2025091220A2 WO 2025091220 A2 WO2025091220 A2 WO 2025091220A2 CN 2023128349 W CN2023128349 W CN 2023128349W WO 2025091220 A2 WO2025091220 A2 WO 2025091220A2
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WO
WIPO (PCT)
Prior art keywords
composition
acid
fatty acid
hydroxypropane
glyceryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2023/128349
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English (en)
Inventor
Feixue TENG
Xiaomin WENG
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOreal SA
Original Assignee
LOreal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LOreal SA filed Critical LOreal SA
Priority to PCT/CN2023/128349 priority Critical patent/WO2025091220A2/fr
Publication of WO2025091220A2 publication Critical patent/WO2025091220A2/fr
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/062—Oil-in-water emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/602—Glycosides, e.g. rutin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/673—Vitamin B group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/673—Vitamin B group
    • A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair

Definitions

  • the present invention relates to a cosmetic composition.
  • the present invention relates to a composition in the form of oil-in-water emulsion.
  • the present invention also relates to a non-therapeutic method for caring for and/or making up keratin materials.
  • Different cosmetic products will comprise different cosmetic active ingredients due to the desired use.
  • Hydroxypropyl tetrahydropyrantriol is a sugarprotein hybrid derived from xylose, a natural sugar found abundantly in beech trees. It can promote the production of collagen and skin’s natural moisturizers, such as hyaluronic acid. Hence, it can help slow down skin aging and give a plump appearance.
  • Niacinamide also called VB3
  • VB3 can protect and sooth the skin.
  • compositions preferably caring for and/or making up of keratin materials, which comprises a relatively high content of hydroxypropyl tetrahydropyrantriol and/or a similar compound and a relatively high content of niacinamide and/or a derivative thereof.
  • It is an object of the present invention to develop stable compositions comprising a relatively high content of hydroxypropyl tetrahydropyrantriol and/or a similar compound and a relatively high content of niacinamide and/or a derivative thereof, which are stable.
  • compositions comprising a relatively high content of hydroxypropyl tetrahydropyrantriol and/or a similar compound and a relatively high content of niacinamide and/or a derivative thereof, which are stable.
  • the present invention relates to a composition in the form of oil-in-water emulsion, preferably for caring for and/or making up keratin materials, comprising:
  • At least one nonionic surfactant selected from glyceryl C14-C22 fatty acid ester, polyoxyethylenated C14-C22 fatty acid ester, and mixtures thereof;
  • composition of the present invention is in the form of an oil-in-water emulsion.
  • said composition comprises a continuous aq ueous phase and a dispersed oily phase.
  • composition of the present invention is stable, i.e. there is no phase separation after having been rotated at4000 rpm/min for 4 hours at 45°C.
  • the present invention relates to a non-therapeutic method for caring for and/or making u p keratin materials, comprising applying the composition according to the present invention to the keratin materials.
  • the term “comprising” is to be interpreted as encompassing all specifically mentioned features as well optional, additional, unspecified ones. As used herein, the use of the term “comprising” also discloses the em bodiment wherein no features other than the specifically mentioned features are present (i.e. “consisting of” ) .
  • n umerical values expressing amount of ingredients and the like which are used in the description and claims are to be understood as being modified by the term “about” . Accordingly, unless indicated to the contrary, the n umerical values and parameters described herein are approximate values which are capable of being changed according to the desired purpose as required.
  • keratin materials refer to the skin and the lips.
  • skin we intend to mean all the body skin, including the scalp.
  • the keratin material is the facial skin.
  • composition according to the present invention comprises:
  • At least one nonionic surfactant selected from glyceryl C14-C22 fatty acid ester, polyoxyethylenated C14-C22 fatty acid ester, and mixtures thereof;
  • the composition of the present invention comprises at least one saturated C14-C22 fatty acid.
  • saturated C14-C22 fatty acid mention can be made of myristic acid, pentadecanoic acid, palmitic acid, heptadecanoic acid, stearic acid, cetearylic acid, arachidic acid, behenic acid, and combinations thereof.
  • the fatty acid is selected from saturated C14-C18 fatty acids.
  • the fatty acid is selected from linear and saturated C14-C18 fatty acids.
  • the fatty acid is selected from myristic acid, palmitic acid, stearic acid, and combinations thereof.
  • the saturated C14-C22 fatty acid is present in an amount ranging from 0.5 wt. %to 30 wt. %, preferably from 0.8 wt. %to 10 wt. %, more preferably from 1 wt. %to 7 wt. %, relative to the total weight of the composition.
  • the composition of the present invention comprises at least one nonionic surfactant selected from glyceryl C14-C22 fatty acid ester, polyoxyethylenated C14-C22 fatty acid ester, and mixtures thereof.
  • glyceryl C14-C22 fatty acid ester means an ester of glycerol and a C14-C22 fatty acid.
  • the C14-C22 fatty acid can be an unsaturated or satu rated, linear or branched acid, for example, stearic acid, isostearic acid, oleic acid, palmitic acid, and/or myristic acid.
  • glyceryl C14-C22 fatty acid ester examples include glyceryl oleate, glyceryl stearate, glyceryl isostearate, glyceryl palmitate, glyceryl myristate, glyceryl arachidate, glyceryl behenate, and mixtures thereof.
  • polyoxyethylenated C14-C22 fatty acid ester is an ester of polyethylene glycol and a C14-C22 fatty acid.
  • the C14-C24 fatty acid can be an unsaturated or saturated, linear or branched acid, for example, stearic acid, isostearic acid, oleic acid, palmitic acid, and/or myristic acid.
  • the polyethylene glycol comprises from1to200oxyethylene groups. More preferably, the polyethylene glycol comprises from 10 to 150 oxyethylene groups. Most preferably, the polyethylene glycol comprises from 20 to 100 oxyethylene groups.
  • the nonionic surfactant is selected from glyceryl esters of a saturated C14-C22 fatty acid, esters of polyethylene glycol comprising from 10 to 150 oxyethylene groups and a saturated C14-C22 fatty acid, and combinations thereof.
  • the nonionic surfactant is selected from glyceryl stearate, glyceryl isostearate, glyceryl palmitate, glyceryl myristate, esters of polyethylene glycol comprising from 20 to 100 oxyethylene groups and a C14-C22 fatty acid selected from myristic acid, palmitic acid, stearic acid and isostearic acid, an d combinations thereof.
  • the surfactant is selected from glyceryl stearate, PEG-100 stearate, and a mixture thereof.
  • the nonionic surfactant is a mixture of glyceryl stearate, glyceryl isostearate, glyceryl pal mitate, glyceryl myristate, and esters of polyethylene glycol comprising from 20 to 100 oxyethylene groups and a C14-C22 fatty acid selected from myristic acid, palmitic acid, stearic acid and isostearic acid.
  • the nonionic surfactant is a mixture of glyceryl stearate and PEG-100 stearate.
  • the nonionic surfactant is present in the composition according to the present invention in an amount ranging from 0.2 wt. %to 20 wt. %, preferably from 0.4 wt. %to 15 wt. %, more preferably from 0.8 wt. %to 12 wt. %, relative to the total weight of the composition.
  • the composition according to the present invention can have a lamellar structure, the structure can help build up the viscosity of the composition and increase the stablity of the composition.
  • the weight ratio of the at least one saturated C14-C22 fatty acids to the at least one nonionic surfactant selected from glyceryl C14-C22 fatty acid ester, polyoxyethylenated C14-C22 fatty acid ester, and mixtures thereof is less than2.5, preferably less than1.8.
  • the composition of the present invention comprises at least 8 wt. %of at least one C-glycoside, relative to the total weight of the composition.
  • the C-glycoside is selected from compounds of formula (I) :
  • R represents a saturated C 1 to C 10 , in particu lar C 1 to C 4 , alkyl radical which can optionally be su bstituted by at least one radical selected from OH, COOH or COOR” 2 , with R” 2 being a saturated C 1 -C 4 alkyl radical,
  • - S represents a monosaccharide or a polysaccharide comprising up to 20 sugar units, in particu lar up to 6 sugar units, in pyranose and/or furanose form and of the L and/or D series, it being possible for the said monosaccharide or polysaccharide to be substituted by a hydroxyl group which is necessarily free and optionally one or more optionally protected amine functional group (s) , and
  • - X represents a radical selected from the–CO-, -CH (OH) -, -CH (N H 2 ) -, -CH (N HCH 2 CH 2 CH 2 OH) -, -CH (NHPh) -and–CH (CH 3 ) -groups and in particu lar a–CO-, -CH (OH) -or–CH (N H 2 ) -radical and more particularly a–CH (OH) -radical,
  • the S-CH 2 -X bond represents a bond of C-anomeric nature, which can be ⁇ or ⁇ ,
  • the C-glycoside of use for the implementation of the invention are in particular those for which R denotes a saturated linear C 1 to C 6 , in particular C 1 to C 4 , preferentially C 1 to C 2 , alkyl radical and more preferably a methyl radical.
  • a monosaccharide of the invention can be selected from D-glucose, D-galactose, D-mannose, D-xylose, D-lyxose or L-fucose, L-arabinose, L-rhamnose, D-glucuronic acid, D-galacturonic acid, D-id uronic acid, N-acetyl-D-glucosamine or N-acetyl-D-galactosamine and advantageously denotes D-glucose, D-xylose, N-acetyl-D-glucosamine or L-fucose and in particular D-xylose.
  • a polysaccharide of the invention comprising up to 6 sugar units can be selected from D-maltose, D-lactose, D-cellobiose, D-maltotriose, a disaccharide combining a uronic acid selected from D-iduronic acid or D-glucuronic acid with a hexosamine selected from D-galactosamine, D-glucosamine, N-acetyl-D-galactosamine or N-acetyl-D-glucosamine, an oligosaccharide comprising at least one xylose which can advantageously be selected from xylobiose, methyl- ⁇ -xylobioside, xylotriose, xylotetraose, xylopentaose and xylohexaose and in particular xylobiose, which is composed of two xylose molecules linked via a 1-4 bond.
  • S can represent a monosaccharide selected from D-glucose, D-xylose, L-fucose, D-galactose or D-maltose and in particu lar D-xylose.
  • - R denotes an unsubstituted linear C 1 -C 4 , in particular C 1 -C 2 , alkyl radical, especially a methyl radical;
  • - S represents a monosaccharide as described above and selected in particular from D-glucose, D-xylose, N-acetyl-D-glucosamine or L-fucose, and in particular D-xylose;
  • - X represents a group selected from-CO-, -CH (OH) -or-CH (N H 2 ) -and
  • the acceptable salts of the compounds described in the present invention comprise conventional non-toxic salts of the said compounds, such as those formed from organic or inorganic acids. Mention may be made, by way of example, of the salts of inorganic acids, such as sulfuric acid, hydrochloric acid. Mention may also be made of the salts of organic acids, which can comprise one or more carboxylic, sulfonic or phosphonic acid groups. Mention may in particular be made of propionic acid, acetic acid, terephthalic acid, citric acid and tartaric acid.
  • neutralization of the acid group (s) can be carried out with an inorganic base, such as LiOH, NaOH, KOH, Ca (OH) 2 , NH 4 OH, Mg (OH) 2 or Zn (OH) 2 , or with an organic base, such as a primary, secondary or tertiary alkylamine, for example triethylamine or butylamine.
  • an inorganic base such as LiOH, NaOH, KOH, Ca (OH) 2 , NH 4 OH, Mg (OH) 2 or Zn (OH) 2
  • organic base such as a primary, secondary or tertiary alkylamine, for example triethylamine or butylamine.
  • This primary, secondary or tertiary alkylamine can comprise one or more nitrogen and/or oxygen atoms and can thus comprise, for example, one or more alcohol functional groups; mention may in particular be made of 2-amino-2-methylpropanol, triethanolamine, 2- (dimethylamino) propanol or2-amino-2- (hydroxymethyl) -1, 3-propanediol. Mention may also be made of lysine or3- (dimethylamino) propylamine.
  • solvates which are acceptable for the compounds described in the present invention comprise conventional solvates, such as those formed during the final stage of preparation of the said compounds due to the presence of solvents. Mention may be made, by way of example, of the solvates due to the presence of water or of linear or branched alcohols, such as ethanol or isopropanol.
  • a C-glycoside corresponding to the formu la (I) can be used alone or as a mixture with other C-glycoside and in any proportion.
  • a C-glycoside which is suitable for the invention can in particu lar be obtained by the synthetic method described in the document WO 02/051828.
  • C- ⁇ -D-xylopyranoside-2-hydroxypropane or C- ⁇ -D-xylopyranoside-2-hydroxypropane and better still C- ⁇ -D-xylopyranoside-2-hydroxypropane can advantageously be used for the preparation of a composition according to the invention.
  • the C-glycoside can be C- ⁇ -D-xylopyranoside-2-hydroxypropane (or hydroxypropyl tetrahydropyrantriol) provided in the form of a solution containing70%by weight of active material in water and propylene glycol.
  • the C-glycoside is present in the composition in an amount ranging from8wt. %to30%, preferably from9wt. %to20wt. %, more preferably from9.5wt. %to15wt. %, relative to the total weight of the composition.
  • the composition of the present invention comprises at least2wt. %of niacinamide and/or a derivative thereof, relative to the total weight of the composition.
  • Niacinamide also called Vitamin B3
  • Vitamin B3 is a compound of the following formula:
  • Niacinamide derivatives that may be mentioned include, for example, nicotinic acid, nicotinyl alcohol, nicotinuric acid, niconityl hydroxamic acid, nicotinic acid esters such as tocopherol nicotinate, amides derived from niacinamide by substitution of the hydrogen of-CONH 2 , products from reaction with carboxylic acids and amino acids, esters of nicotinyl alcohol and of carboxylic acids such as acetic acid, salicyclic acid, glycolid acid or palmitic acid.
  • niacinamide and/or a derivative thereof is present in the composition of the present invention in an amount ranging from 2 wt. %to 20 wt. %, preferably from 3 wt. %to 15 wt. %, and more preferably from 4 wt. %to 10 wt. %, relative to the total weight of the composition.
  • the composition of the present invention comprises a continuous aqueous phase.
  • Said aqueous phase is preferably present in an amount ranging from 10 wt. %to 85 wt. %, more preferably from 20 wt. %to 85 wt. %, relative to the total weight of the composition.
  • the continuous aqueous phase comprises water.
  • Water is preferably present in the composition of the present invention in an amount ranging from 10 wt. %to 85 wt. %, preferably from 20 wt. %to 80 wt. %, relative to the total weight of the composition.
  • the continuous hydrophilic phase comprises at least one organic solvent miscible with water (at room temperature 25°C) such as for example monoalcohols having from 2 to 6 carbon atoms such as ethanol, isopropanol; polyols having from 2 to 20 carbon atoms, preferably from 2 to 10 carbon atoms, and preferentially having from 2 to 6 carbon atoms, such as glycerin, propylene glycol, butylene glycol, pentylene glycol, hexylene glycol, caprylyl glycol, dipropylene glycol, diethylene glycol; glycol ethers (notably having from 3 to 16 carbon atoms) such as mono-, di-or tri-propylene glycol (C 1 -C 4 ) alkyl ethers, mono-, di-or tri-ethylene glycol (C 1 -C 4 ) alkyl ethers and mixtures thereof.
  • organic solvent miscible with water at room temperature 25°C
  • monoalcohols having from 2 to 6
  • the organic solvent is preferably present in the composition of the present invention in an amount ranging from 1wt. %to 30 wt. %, preferably from 1 wt. %to 25 wt. %, more preferably from 5 wt. %to 20 wt. %, relative to the total weight of the composition.
  • the composition of the present invention further comprises a dispersed oily phase.
  • the oily phase contains at least one oil, notably a cosmetic oil. It may also contain other fatty substances such as waxes, for example beeswax.
  • oil means a water-immiscible non-aq ueous compound that is liquid at room temperature (20°C) and at atmospheric pressure (760 mm Hg) .
  • the oils may be volatile or non-volatile.
  • non-volatile refers to an oil whose vapor pressure at room temperature and atmospheric pressure is non-zero and is less than 10 -3 mm Hg (0.13 Pa) .
  • volatile oil means any oil that is capable of evaporating in contact with the skin in less than one hour, at room temperature and atmospheric pressure.
  • the oily phase may comprise hydrocarbon-based oils, silicone oils such as dimethicone, or mixtu res thereof.
  • They may be of animal, plant, mineral or synthetic origin.
  • hydrocarbon-based oil means an oil mainly containing hydrogen and carbon atoms.
  • silicon oil means an oil comprising at least one silicon atom, and notably at least one Si-O group.
  • the oils may optionally comprise oxygen, nitrogen, sulfur and/or phosphorus atoms, for example in the form of hydroxyl or acid radicals.
  • the oil is a hydrocarbon-based oil, more preferably is isononyl isononanoate.
  • the oily phase is present in the composition of the present invention in an amount ranging from 1 wt. %to 30 wt. %, preferably from 5 wt. %to 20 wt. %, relative to the total weight of the composition of the present invention.
  • composition of the present invention may comprise an additional cosmetic active ingredient.
  • moisturizing agents As examples of additional cosmetic active ingredients, mention can be made of moisturizing agents; brightening agents; tightening agents; peeling agents; repairing and soothing agents; agents acting on the microcirculation, and mixtures thereof.
  • the cosmetic composition of the present invention may also contain conventional cosmetic adjuvants or additives, for instance fragrances, chelating agents, preserving agents and bactericides, additional surfactants (for example, nonionic surfactant such as C12-C22 fatty alcohol, C12-C22 alkyl glucoside) , thickeners such as sodium polyacrylate, carbomer, ammonium polyacryloyldimethyltaurate, xanthan gum, fillers, pH regulators, saponifiers (such as potassium hydroxide) , and mixtures thereof.
  • fragrances for instance, chelating agents, preserving agents and bactericides
  • additional surfactants for example, nonionic surfactant such as C12-C22 fatty alcohol, C12-C22 alkyl glucoside
  • thickeners such as sodium polyacrylate, carbomer, ammonium polyacryloyldimethyltaurate, xanthan gum, fillers, pH regulators, saponifiers (such as potassium hydroxide)
  • the present invention provides a composition in the form of an oil-in-water emulsion, preferably for caring for and/or making up keratin materials, comprising, relative to the total weight of the composition:
  • nonionic surfactant selected from glyceryl laurate, glyceryl stearate, glyceryl isostearate, glyceryl palmitate, glyceryl myristate, esters of polyethylene glycol comprising from 20 to 100 oxyethylene groups and a C14-C22 fatty acid selected from lauric acid, myristic acid, palmitic acid and stearic acid, and combinations thereof;
  • composition of the present invention can be used for caring for and/or making up keratin materials.
  • the present invention relates to a non-therapeutic method for caring for and/or making up keratin materials, comprising applying the composition according to the present invention to the keratin materials.
  • the keratin material can be the skin, for example the facial skin.
  • compositions of invention example (IE) 1 and comparative examples (CE) 1-3 were prepared based on the amounts given in Table 2. The amounts are given in%by weight of active ingredient relative to the total weight of the composition.
  • Composition of invention example 1 represents a composition according to the present invention.
  • Composition of comparative example 1 does not comprise at least one nonionic surfactant selected from glyceryl C14-C22 fatty acid ester, polyoxyethylenated C14-C22 fatty acid ester, and mixtures thereof.
  • Composition of comparative example 2 does not comprise at least one saturated C14-C22 fatty acid.
  • Composition of comparative example 3 does not comprise at least one saturated C14-C22 fatty acid and at least one nonionic surfactant selected from glyceryl C14-C22 fatty acid ester, polyoxyethylenated C14-C22 fatty acid ester, and mixtures thereof.
  • compositions listed above were prepared as follows, taking the composition of invention example 1 as an example:
  • composition to be evaluated was contained in a sample tube and put into the machine.
  • the machine ran under pre-set protocol, which are 4000 rpm/min, 4 hours, and at 45°C.
  • the composition passes in the stability test.
  • compositions of invention example 1 and comparative examples 1-3 were summarized below.
  • composition of invention example 1 is stable.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Cosmetics (AREA)

Abstract

La présente invention concerne une composition sous forme d'émulsion huile dans l'eau, comprenant : (i) au moins un acide gras en C14-C22 saturé ; (ii) au moins un tensioactif non ionique choisi parmi l'ester d'acide gras en C14-C22 de glycéryle, l'ester d'acide gras en C14-C22 polyoxyéthyléné et des mélanges de ceux-ci ; (iii) au moins 8 % en poids d'au moins un C-glycoside, par rapport au poids total de la composition ; et (iv) au moins 2 % en poids de niacinamide et/ou d'un dérivé de celui-ci, par rapport au poids total de la composition. La présente invention concerne également un procédé non thérapeutique de soin et/ou de maquillage de matières kératiniques.
PCT/CN2023/128349 2023-10-31 2023-10-31 Composition sous forme d'émulsion huile dans l'eau Ceased WO2025091220A2 (fr)

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PCT/CN2023/128349 WO2025091220A2 (fr) 2023-10-31 2023-10-31 Composition sous forme d'émulsion huile dans l'eau

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PCT/CN2023/128349 WO2025091220A2 (fr) 2023-10-31 2023-10-31 Composition sous forme d'émulsion huile dans l'eau

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WO2025091220A2 true WO2025091220A2 (fr) 2025-05-08

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PCT/CN2023/128349 Ceased WO2025091220A2 (fr) 2023-10-31 2023-10-31 Composition sous forme d'émulsion huile dans l'eau

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