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WO2024263848A3 - Method for using transepidermal water loss as a clinical biomarker of wound recurrence - Google Patents

Method for using transepidermal water loss as a clinical biomarker of wound recurrence Download PDF

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Publication number
WO2024263848A3
WO2024263848A3 PCT/US2024/034918 US2024034918W WO2024263848A3 WO 2024263848 A3 WO2024263848 A3 WO 2024263848A3 US 2024034918 W US2024034918 W US 2024034918W WO 2024263848 A3 WO2024263848 A3 WO 2024263848A3
Authority
WO
WIPO (PCT)
Prior art keywords
water loss
transepidermal water
clinical biomarker
loss value
wound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/US2024/034918
Other languages
French (fr)
Other versions
WO2024263848A2 (en
Inventor
Chandan K. Sen
Sashwati Roy
Gayle M. Gordillo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Indiana University
Indiana University Bloomington
Original Assignee
Indiana University
Indiana University Bloomington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indiana University, Indiana University Bloomington filed Critical Indiana University
Publication of WO2024263848A2 publication Critical patent/WO2024263848A2/en
Publication of WO2024263848A3 publication Critical patent/WO2024263848A3/en
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
    • A61B5/445—Evaluating skin irritation or skin trauma, e.g. rash, eczema, wound, bed sore
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • A61B5/015—By temperature mapping of body part
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4869—Determining body composition
    • A61B5/4875—Hydration status, fluid retention of the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

A method for determining functionality of healed wound tissue or skin susceptible to formation of pressure wounds includes measuring transepidermal water loss at a reference location to determine a first transepidermal water loss value, measuring transepidermal water loss within the healed wound tissue or within the skin susceptible to the formation of a pressure wound to determine a second transepidermal water loss value, and comparing the second transepidermal water loss value to the first transepidermal water loss value.
PCT/US2024/034918 2023-06-23 2024-06-21 Method for using transepidermal water loss as a clinical biomarker of wound recurrence Pending WO2024263848A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202363509940P 2023-06-23 2023-06-23
US63/509,940 2023-06-23
US202363518244P 2023-08-08 2023-08-08
US63/518,244 2023-08-08

Publications (2)

Publication Number Publication Date
WO2024263848A2 WO2024263848A2 (en) 2024-12-26
WO2024263848A3 true WO2024263848A3 (en) 2025-05-15

Family

ID=93936258

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2024/034918 Pending WO2024263848A2 (en) 2023-06-23 2024-06-21 Method for using transepidermal water loss as a clinical biomarker of wound recurrence

Country Status (1)

Country Link
WO (1) WO2024263848A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190110740A1 (en) * 2015-12-30 2019-04-18 James G. Spahn System, apparatus and method for assessing wound and tissue conditions
US20220240840A1 (en) * 2021-02-03 2022-08-04 Bruin Biometrics, Llc Methods of treating deep and early-stage pressure induced tissue damage
US20220386941A1 (en) * 2019-11-15 2022-12-08 Bruin Biometrics, Llc Transepidermal Water Loss

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190110740A1 (en) * 2015-12-30 2019-04-18 James G. Spahn System, apparatus and method for assessing wound and tissue conditions
US20220386941A1 (en) * 2019-11-15 2022-12-08 Bruin Biometrics, Llc Transepidermal Water Loss
US20220240840A1 (en) * 2021-02-03 2022-08-04 Bruin Biometrics, Llc Methods of treating deep and early-stage pressure induced tissue damage

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ABIAKAM NKEMJIKA S., JAYABAL HEMALATHA, FILINGERI DAVIDE, BADER DAN L., WORSLEY PETER R.: "Spatial and temporal changes in biophysical skin parameters over a category I pressure ulcer", INTERNATIONAL WOUND JOURNAL, vol. 20, no. 8, 1 October 2023 (2023-10-01), UK , pages 3164 - 3176, XP093314952, ISSN: 1742-4801, DOI: 10.1111/iwj.14194 *
KOTTNER JAN, BLUME‐PEYTAVI ULRIKE: "Reliability and agreement of instrumental skin barrier measurements in clinical pressure ulcer prevention research", INTERNATIONAL WOUND JOURNAL, vol. 18, no. 5, 1 October 2021 (2021-10-01), UK , pages 716 - 727, XP093314961, ISSN: 1742-4801, DOI: 10.1111/iwj.13574 *

Also Published As

Publication number Publication date
WO2024263848A2 (en) 2024-12-26

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