[go: up one dir, main page]

WO2020170084A1 - Dispositif pour faciliter l'administration de gouttes oculaires - Google Patents

Dispositif pour faciliter l'administration de gouttes oculaires Download PDF

Info

Publication number
WO2020170084A1
WO2020170084A1 PCT/IB2020/051184 IB2020051184W WO2020170084A1 WO 2020170084 A1 WO2020170084 A1 WO 2020170084A1 IB 2020051184 W IB2020051184 W IB 2020051184W WO 2020170084 A1 WO2020170084 A1 WO 2020170084A1
Authority
WO
WIPO (PCT)
Prior art keywords
eye drops
arms
stretching
aforesaid
bottle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2020/051184
Other languages
English (en)
Inventor
Massimiliano GIOVENALI
Gislero GRECHI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to EP20707324.8A priority Critical patent/EP3927295A1/fr
Publication of WO2020170084A1 publication Critical patent/WO2020170084A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0026—Ophthalmic product dispenser attachments to facilitate positioning near the eye

Definitions

  • the present invention patent application generally refers to the category regarding the instruments suitable for the administration of a medication, and more particularly refers to a device for facilitated administration of eye drops.
  • the invention is applicable to any sector where one such type can be advantageously used, but preferably this regards the ophthalmological field.
  • a bottle of liquid eye drop solution includes a drops dispenser incorporated on the release orifice of the container.
  • the user compresses the bottle, forcing the solution to pass through the release orifice, which by falling is administered into the conjunctival sac of the eye.
  • the aforesaid administration per se appears to be a very simple operation, but in reality on the field this should not be taken for granted.
  • Another relevant problem, associated with the devices of the prior art, consists of maintaining the sterility of ophthalmic solutions that are dispensed by the bottle through a dropper tip, which can be contaminated by means of exposure or contact.
  • all the currently-sold multidose bottles rather high amounts of antiseptic compounds, capable of protecting the solution against bacterial and viral contamination. Nevertheless, these antiseptics are often irritating and can be toxic for the sensitive tissues surrounding and within the eye.
  • one object of the present finding generally consists of making a device usable with the most common containers for liquid eye drops currently present on the market, or with the container for eye drops already integrated at its interior, capable of solving part of the abovementioned problems connected with the state of the art.
  • object of the present finding is that of administering the ophthalmic drops in a controlled manner, by delicately attaining the opening of the eyelids in a manner coordinated with the release of the solution itself.
  • a further object of the present finding consists of avoiding the contact of the aforesaid dispensing spouts and hence of protecting the solution contained in the container from possible inevitable microbial contaminations.
  • Another further possible object of the present invention is to attain a device capable of making a controllable dispensing of the eye drops themselves.
  • the present industrial invention patent application intends to describe and claim an innovative device, or a system for administration of eye drops, capable of being used with the main categories of pressable containers for liquid eye drops existing on the market, i.e. with multidose bottles and the single-dose vials or with the container of the eye drops already integrated at its interior.
  • our proposal assumes the design of an eye drop dispensing device, which allows being lightly rested against the closed eyelids and, due to the pressure exerted by the fingers on the device itself, executing a limited but sufficient opening of the eyelid edge synchronous with the dispensing of the eye drops and hence making the entrance of the eye drops in a facilitated and approached manner.
  • the innovative concept underlying the present invention specifically consists of providing for said innovative device made by means of two stretching arms for opening the eyelids, actuatable by the user, in which the relative bases can be rested against the eye socket of the user himself/herself.
  • said two stretching arms for opening the eyelids are shaped in a manner such that the simple pressure of the fingers thereon by the user is capable on one hand of actuating the opening of the eyelids and on the other hand simultaneously achieving the squeezing of the bottle housed therein, with consequent release of drops of the contained and hence administration of the ophthalmic solution into the eye.
  • Another technical characteristic which diversifies the device, object of the present invention is that, due to its shape once the administration is completed, the step of releasing the aforesaid stretching arms for opening the eyelids allows the nearly hermetic closure of the container, by means of lifting a lid which comes to press the spout of the aforesaid container.
  • Such characteristic is in reality essential for the purposes of an optimal administration of the medication, i.e. of the ophthalmic solution, since by preventing any form of contact and hence of contamination of the spout and consequently of the liquid contained in the bottle, it is possible to considerably reduce the amount of antiseptics during the step of formulation of the ophthalmic preparation, as such antiseptics are often irritating and toxic for the surrounding tissues and within the eye.
  • the present invention has as further objective that of proposing a device capable of being used with most of the eye drop containers of the prior art, also by means of the aid of suitable innovative adapters such as those necessary in the case of the single-dose vials.
  • a further objective is to propose a system of administration of eye drops which can be made on industrial scale, whose components are of standard and perfectly retrievable on the market and whose production is fully sustainable from an economical and environmental standpoint.
  • said inventive device for facilitated administration of eye drops can be selected by the man skilled in the art so as to satisfy the technical characteristics in this particular field, including solidity, resistance, sterilizability and lightness; however said materials can comprise those of metal type, preferably steel and/or aluminum and/or polymers of plastic type.
  • said plastic polymer materials or metal materials can comprise those having galvanized external finish and/or dyed external finish and/or having plasticized external finish.
  • one of the advantages of the present device is that of allowing the administration of the eye drops with a single hand.
  • FIGURE 1 is a top perspective view of a device for facilitated administration of eye drops according to the present invention
  • FIGURE 2 is the top perspective view of the inventive device with the front portion sectioned for representative purposes;
  • FIGURE 3 is a plan view of the inventive device
  • FIGURE 4 is a view of the lower part of the inventive device
  • FIGURE 5 is a top perspective view of a further embodiment of the inventive device.
  • FIGURE 6 is a top perspective view of an alternative embodiment of the inventive device, for display purposes lacking the covering. Description of several embodiments of the invention
  • the device for facilitated administration of eye drops substantially comprises, in a preferred embodiment of the invention, a main housing element 100 with cylindrical shape, having the upper end 110 open in order to allow the introduction and removal of a common bottle 300 containing the eye drops, and the lower end made with a lower hole 120 (Fig. 2) capable of receiving the spout of said bottle 300 containing the eye drops.
  • a main housing element 100 with cylindrical shape, having the upper end 110 open in order to allow the introduction and removal of a common bottle 300 containing the eye drops, and the lower end made with a lower hole 120 (Fig. 2) capable of receiving the spout of said bottle 300 containing the eye drops.
  • At said lower hole 120 at least two resilient stabilization fins 130 are present, capable of reversibly engaging and locking the aforesaid bottle 300 containing the eye drops.
  • at least two longitudinal openings 170 are provided on the main housing element 100.
  • the two stretching arms 200 for opening the eyelids are present in diametrically opposite positions.
  • Said stretching arms 200 are each connected to the main housing element 100 by means of a common articulated connection system 140 (Fig. 1), capable of allowing a rotary motion around the axis thereof and characterized in that said articulated connection system 140 conceptually divides each of said stretching arms 200 into an upper arm 210 and into a lower arm 220.
  • the ends 215 of said upper arms 210 terminate folded orthogonally towards the external, so as to form a valid support for the fingers of the user and a stable abutment base, when the device is placed overturned with the bottle 300 inserted.
  • said upper arms 210 also have the compression protrusions 230 medially directed and capable, during the approaching of the stretching arms 200 or the closing thereof by the pressure exerted by the fingers of the user, of engaging and pressing by means of corresponding openings 160, made in the main housing element 100, the relative bottle 300 containing the eye drops and consequently compressing it so that it releases the ophthalmic solution by means of the spout thereof.
  • the lower arms 220 carry out a double function, since on one hand they attain, by means of the respective lower ends, the stretching portions 250 and on the other hand they support the system for closing the bottle 300 containing the eye drops.
  • Said closing function occurs by means of the presence of the support elements 400 of the closing lid 450 directed medially; due to the inventive shape such elements attain a closing of the spout of the bottle 300 only when the two stretching arms 200 are in inoperative/rest position, i.e. with the two support elements 400 in lifted position.
  • Fig. 1-2 and 4 show the two stretching portions 250 of said stretching arms 200, which due to the inventive shape, by resting against the eyelids of the user, operate a rather delicate opening of the same, maintaining them in open position until the eye drops have been administered.
  • the stretching portions 250 of the device which come into contact with the eyelids closed, are represented by a semi-lunar shape, such aforesaid shape must not be considered as limiting for the invention, since these can be made of any one shape and of such such to constitute a valid means capable of coming into contact with the eyelids and causing a controlled opening thereof.
  • said stretching portions 250 be constituted by a rigid framework on which a comfortable shell 260 is applied that is made of semi-rigid and soft-rubbery resilient plastic material such as silicon and/or rubber and so forth, so as to allow a natural contact, also capable of imparting a pleasant sensation to the user.
  • the operation of said device is intentionally not complex, such that the closing of the stretching arms 200 by the user creates a synchronous action between the pressing of the bottle 300 containing the eye drops, by means of the compression protrusions 230 and a limited but sufficient opening of the eyelid edge by means of the stretching portions 250, thus enabling the correct administration of the eye drops in the conjunctival sac or on the cornea in a facilitated and approached manner.
  • a further aspect, at the margin of all the technical solutions described up to now, but of particular importance in the attainment of the invention, is that in those cases where a container is used for liquid eye drops constituted by a single-dose vial 350, such as that represented in Fig.
  • an inventive adapter 500 in which aforesaid single-dose vial 350 is inserted.
  • the right direction for inserting said adapter 500 in the main housing element 100 will be attained due to the correspondence between the aforesaid upper stabilization teeth 180 and the longitudinal guides 510 made on the aforesaid inventive adapter 500.
  • the material constituting said adapter 500 must be such to easily transmit the compression forces exerted by the compression protrusions 230 on the aforesaid single-dose vial 350 housed within and for such purpose, advantageously, rigid elastic polymeric material such as natural and synthetic rubbers are used.
  • the present invention provides for a further alternative embodiment at several variants of its structure and of the shape of its components, which however must not at all be considered less essential for the purposes of attainment of the same invention.
  • said device container for eye drops 600 will be inventively constituted by a container having a shape such to allow the exact gripping or the immediate identification of the correct point where to place the user’s fingers, represented by the knurled area 610.
  • Said stretching arms 200 as represented in Fig. 6, or the upper arms 210 and the lower arms 220, are entirely constituted by a rigid plastic polymer material and characterized in that the portions constituting the upper arms 210 are fully made in the wall of said container for eye drops 600, which is instead made of a semi-rigid plastic polymer material or provided in any case with a considerable elasticity.
  • Such aforesaid elasticity will be such to allow the deformation thereof and hence the approaching of the upper arms 210, actively induced by the pressure of the user’s fingers on the knurled area 610 and consequently the release of the eye drops and the synchronous opening of the lower arms 220 and hence of the stretching portions 250 for opening the eyelids and vice versa a passive return into inoperative/rest position of the aforesaid stretching arms 200 once the aforesaid pressure has ceased.
  • the aforesaid container for eye drops 600 will be provided in a lower and central portion, at the lower arms 220 and just above the stretching portions 250 of the spout of the container 650.
  • Said spout of the container 650 is advantageously made of silicone and is valve-like by means of a small medial slit forming the eye drops release orifice. Said spout of the container 650 will be opened by breaking a closure seal, along with a common tongue adhered to the same or by removing the relative closure cap.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne un dispositif pour faciliter l'administration de gouttes oculaires qui comprend un élément de boîtier principal (100) de forme cylindrique, comportant une extrémité supérieure (110) ouverte pour loger une bouteille standard (300) contenant des gouttes oculaires, et une extrémité inférieure pourvue d'un trou (120) apte à recevoir le bec de ladite bouteille (300), deux bras d'étirement (200) pour ouvrir les paupières étant munis de saillies de compression (230) appropriées pour presser la bouteille (300) de façon à la comprimer jusqu'à ce qu'elle libère une solution ophtalmique au moyen de son bec, les extrémités inférieures desdits bras d'étirement (200) étant munis de parties d'étirement (250) sur lesquelles est appliquée une enveloppe confortable (260) pouvant reposer contre les paupières et les ouvrir de manière synchrone à l'approche des bras d'étirement (200), ce qui leur permet de rester en position ouverte jusqu'à ce que l'administration soit achevée.
PCT/IB2020/051184 2019-02-18 2020-02-13 Dispositif pour faciliter l'administration de gouttes oculaires Ceased WO2020170084A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP20707324.8A EP3927295A1 (fr) 2019-02-18 2020-02-13 Dispositif pour faciliter l'administration de gouttes oculaires

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT102019000002327A IT201900002327A1 (it) 2019-02-18 2019-02-18 Dispositivo per l’instillazione facilitata di colliri
IT102019000002327 2019-02-18

Publications (1)

Publication Number Publication Date
WO2020170084A1 true WO2020170084A1 (fr) 2020-08-27

Family

ID=66867630

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2020/051184 Ceased WO2020170084A1 (fr) 2019-02-18 2020-02-13 Dispositif pour faciliter l'administration de gouttes oculaires

Country Status (3)

Country Link
EP (1) EP3927295A1 (fr)
IT (1) IT201900002327A1 (fr)
WO (1) WO2020170084A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113397807A (zh) * 2021-06-03 2021-09-17 四川大学 一种可定量点眼药水且可循环利用的眼药水瓶
WO2024224251A1 (fr) * 2023-04-27 2024-10-31 Alcon Inc. Cadre flexible pour utilisation avec distributeurs de fluides flexibles
WO2025101712A1 (fr) * 2023-11-09 2025-05-15 Any Eye Llc Récipient et distributeur de gouttes ophtalmiques et procédé de distribution d'un médicament ou d'une solution ophtalmique

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090259204A1 (en) * 2008-04-14 2009-10-15 Shabty Galdeti Method and Device for Applying Eye Drops
US20100286634A1 (en) * 2008-02-05 2010-11-11 Marx Alvin J Automated Eyedrop Delivery System with Eyelid Retracting Legs
US20120310184A1 (en) * 2010-01-22 2012-12-06 First Aid Company Aps Handheld apparatus for eye-washing
RO129427A2 (ro) * 2008-05-30 2014-05-30 Universitatea "Transilvania" Din Braşov Instilator oftalmic
CN106821431A (zh) * 2017-02-16 2017-06-13 成都迅德科技有限公司 一种医用开睑器

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100286634A1 (en) * 2008-02-05 2010-11-11 Marx Alvin J Automated Eyedrop Delivery System with Eyelid Retracting Legs
US20090259204A1 (en) * 2008-04-14 2009-10-15 Shabty Galdeti Method and Device for Applying Eye Drops
RO129427A2 (ro) * 2008-05-30 2014-05-30 Universitatea "Transilvania" Din Braşov Instilator oftalmic
US20120310184A1 (en) * 2010-01-22 2012-12-06 First Aid Company Aps Handheld apparatus for eye-washing
CN106821431A (zh) * 2017-02-16 2017-06-13 成都迅德科技有限公司 一种医用开睑器

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113397807A (zh) * 2021-06-03 2021-09-17 四川大学 一种可定量点眼药水且可循环利用的眼药水瓶
WO2024224251A1 (fr) * 2023-04-27 2024-10-31 Alcon Inc. Cadre flexible pour utilisation avec distributeurs de fluides flexibles
WO2025101712A1 (fr) * 2023-11-09 2025-05-15 Any Eye Llc Récipient et distributeur de gouttes ophtalmiques et procédé de distribution d'un médicament ou d'une solution ophtalmique

Also Published As

Publication number Publication date
IT201900002327A1 (it) 2020-08-18
EP3927295A1 (fr) 2021-12-29

Similar Documents

Publication Publication Date Title
AU2007330356B2 (en) Metered drop bottle for dispensing microliter amounts of a liquid in the form of a drop
CA2011734C (fr) Distributeur de gouttes
US4960407A (en) Disposable eye drop dispenser instrument for post-surgical and general use
US5382243A (en) Apparatus with indicator for administration of eye medication
US6090086A (en) Eye drop applicator with adjustable guide arm and improved closure system
US5848999A (en) Dispensing eye drops
US20140350492A1 (en) Eyedrop dispenser
WO2020170084A1 (fr) Dispositif pour faciliter l'administration de gouttes oculaires
JPH0337066A (ja) 目薬用点眼具
CA2563365A1 (fr) Systeme d'administration de medicament en doses unitaires multiples
US20110009836A1 (en) Pharmaceutical delivery device
KR101789278B1 (ko) 안약 투약기
US6010488A (en) Lower eyelid retractor and method for applying medication to the eye
JP2003512107A (ja) 医薬品のパッケージ及びパッケージを製造し、滅菌する方法
AU2011377572A1 (en) Apparatus and method for fluid delivery
WO2006043295A1 (fr) Distributeur multidose destine a des preparations de liquides steriles
EP3738557B1 (fr) Dispositif pour récipients à dose unique
US5342327A (en) Eye bottle
US20070179457A1 (en) Device and method for the administration of eye drops
EP3125839B1 (fr) Dispositif et procédé d'administration d'un liquide au goutte-à-goutte
US20050043693A1 (en) Easy drop
EP3308757B1 (fr) Dispositif pour administration oculaire de fluides
US20250041112A1 (en) Adaptable precision ocular fluid medication dispenser
KR200233061Y1 (ko) 안약 투약기
EP3813743A1 (fr) Distributeur pour l'administration d'une seule goutte de liquide pour une application pharmaceutique, enregistré comme médicament ou étant un produit médical, notamment un liquide ophtalmique, ensemble de distribution et utilisation de celui-ci

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 20707324

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

ENP Entry into the national phase

Ref document number: 2020707324

Country of ref document: EP

Effective date: 20210920