[go: up one dir, main page]

WO2020066895A1 - Composition cosmétique destinée à la peau - Google Patents

Composition cosmétique destinée à la peau Download PDF

Info

Publication number
WO2020066895A1
WO2020066895A1 PCT/JP2019/036973 JP2019036973W WO2020066895A1 WO 2020066895 A1 WO2020066895 A1 WO 2020066895A1 JP 2019036973 W JP2019036973 W JP 2019036973W WO 2020066895 A1 WO2020066895 A1 WO 2020066895A1
Authority
WO
WIPO (PCT)
Prior art keywords
component
mass
cosmetic composition
oil
skin cosmetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2019/036973
Other languages
English (en)
Japanese (ja)
Inventor
松尾真樹
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mandom Corp
Original Assignee
Mandom Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mandom Corp filed Critical Mandom Corp
Priority to CN201980043706.7A priority Critical patent/CN112351768A/zh
Priority to KR1020207037364A priority patent/KR102532929B1/ko
Priority to JP2020549123A priority patent/JP6982697B2/ja
Publication of WO2020066895A1 publication Critical patent/WO2020066895A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/26—Optical properties
    • A61K2800/262—Transparent; Translucent

Definitions

  • the present invention relates to a composition for skin cosmetics. More specifically, the present invention relates to an aqueous skin cosmetic composition containing an oil component.
  • Liposomes have a size on the order of 100 nm, are larger than micelles, and can contain more oil in the liposome membrane.
  • the transparency is reduced depending on the particle size of the liposome, and particularly when it is blended in a low-viscosity lotion formulation, the storage stability is poor.
  • an object of the present invention is to provide a skin cosmetic composition which can contain a relatively large amount of oil and is excellent in transparency and storage stability.
  • the present inventors have conducted intensive studies to achieve the above object, and as a result, have found that phospholipids, a specific polyoxyethylene sterol ether and / or a specific polyoxyethylene stanol ether, a specific aliphatic alcohol, and a specific polyoxyethylene sterol ether.
  • the present invention comprises the following component A, the following component B, the following component C, the following component D, the following component E, the following component F, the following component G, and the following component H,
  • a skin cosmetic composition having a mass ratio (B / A) of the component B to the component A of 5.5 to 18.0.
  • Component A Phospholipid Component B: Polyoxyethylene sterol ether having an average addition mole number of oxyethylene of 15 to 50 and / or polyoxyethylene stanol ether having an average addition mole number of oxyethylene of 15 to 50
  • Component C Branched chain Component D: one or more polyhydric alcohols selected from the group consisting of propylene glycol, dipropylene glycol, and 1,3-butylene glycol
  • Component E water
  • Component F Sterol Component
  • G Oil Component H: Polyoxyethylene hydrogenated castor oil having an average added mole number of oxyethylene of 5 to 30
  • composition for skin cosmetics preferably further contains the following component I: Component I: glycerin mono-2-ethylhexyl ether
  • composition for skin cosmetics preferably further contains the following component J.
  • Component J 1,2-alkanediol having 5 to 10 carbon atoms
  • the skin cosmetic composition of the present invention it is possible to provide a skin cosmetic composition which can contain a relatively large amount of oil and is excellent in transparency and storage stability.
  • composition for skin cosmetics of the present invention comprises a phospholipid; polyoxyethylene sterol ether having an average addition mole number of oxyethylene of 15 to 50 and / or polyoxyethylene stanol having an average addition mole number of oxyethylene of 15 to 50.
  • Ether a monovalent aliphatic alcohol having 12 to 24 carbon atoms having a branched chain; at least one polyhydric alcohol selected from the group consisting of propylene glycol, dipropylene glycol and 1,3-butylene glycol; water; sterol; Oil component containing at least polyoxyethylene hydrogenated castor oil having an average addition mole number of oxyethylene of 5 to 30.
  • the phospholipid is referred to as “Component A”, the polyoxyethylene sterol ether having an average addition mole number of oxyethylene of 15 to 50 and / or the polyoxyethylene oxyethylene having an average addition mole number of oxyethylene of 15 to 50.
  • the stanol ether is selected from the group consisting of "Component B”, and the branched chain monovalent aliphatic alcohol having 12 to 24 carbon atoms is selected from the group consisting of "Component C”, propylene glycol, dipropylene glycol and 1,3-butylene glycol.
  • One or more polyhydric alcohols are “Component D”
  • water is “Component E”
  • sterol is “Component F”
  • oil is “Component G”
  • polyoxyethylene cured castor having an average added mole number of oxyethylene of 5 to 30 is used.
  • the oils are sometimes referred to as “Component H” respectively.
  • the skin cosmetic composition of the present invention preferably further contains glycerin mono-2-ethylhexyl ether.
  • the composition for skin cosmetics of the present invention preferably further contains a 1,2-alkanediol having 5 to 10 carbon atoms.
  • the glycerin mono-2-ethylhexyl ether may be referred to as “component I” in some cases.
  • the 1,2-alkanediol having 5 to 10 carbon atoms may be referred to as “component J” in some cases.
  • the composition for skin cosmetics of the present invention contains at least component A, component B, component C, component D, component E, component F, component G, and component H.
  • the skin cosmetic composition of the present invention may further contain component I and / or component J.
  • the composition for skin cosmetics of the present invention may contain components other than the above components A to J.
  • each component contained in the skin cosmetic composition of the present invention for example, component A, component B, component C, component D, component E, component F, component G, component H, component I, component J, and Each component such as other components may be used alone or in combination of two or more.
  • Component A is a "phospholipid". Component A forms a bicellular structure (a disk-shaped lipid bilayer composed of phospholipids), which is a form of micelle. Therefore, a relatively large amount of oil can be included in the bicell structure.
  • Component A is a complex lipid containing a phosphate residue, such as a natural phospholipid, a synthetic phospholipid, or a hydrogenated phospholipid in which the unsaturated carbon chain of a naturally occurring phospholipid is saturated with hydrogen.
  • the phospholipid include natural phospholipids such as phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, phosphatidylinositol, lysophosphatidylcholine, sphingomyelin, egg yolk lecithin, soybean lecithin; Synthetic phospholipids such as stearoyl phosphatidylcholine, dioleoyl phosphatidylcholine, palmitoyl oleoyl phosphatidylcholine; hydrogenated phospholipids such as hydrogenated soybean lecithin, hydrogenated egg yolk lecithin, hydrogenated phosphatidylcholine, hydrogenated phosphatidylser
  • a commercially available product can be used.
  • Commercial products of hydrogenated soybean lecithin include, for example, trade name "COATSOME @ NC-21", trade name "COATSOME @ NC-61" (both manufactured by NOF Corporation), trade name "NIKKOL @ resinol S-10EX", trade name
  • the trade name is "NIKKOL @ Resinol S-10E", the trade name "NIKKOL @ Resinol S-10M” (above, manufactured by Nikko Chemicals Co., Ltd.), and the trade name is "Basis @ LS-60HR” (manufactured by Nisshin Oillio Group Co., Ltd.).
  • the content ratio of the component A in the skin cosmetic composition of the present invention is not particularly limited, but is preferably 0.005% by mass or more based on 100% by mass of the total amount of the skin cosmetic composition of the present invention. It is more preferably at least 0.1% by mass, further preferably at least 0.2% by mass. When the content is 0.005% by mass or more, a bicell structure is formed, the component F is stably dispersed, and the storage stability is further improved.
  • the upper limit of the content is preferably 3.0% by mass or less, more preferably 2.0% by mass or less, and even more preferably 1.5% by mass or less. When the content is 3.0% by mass or less, an excessive increase in viscosity can be suppressed, and the dispersibility can be further improved.
  • the content ratio of the component A is the sum of the content ratios of all the components A in the skin cosmetic composition of the present invention.
  • Component B is "polyoxyethylene sterol ether having an average addition mole number of oxyethylene of 15 to 50 and / or polyoxyethylene stanol ether having an average addition mole number of oxyethylene of 15 to 50". That is, the component B is one or both of the polyoxyethylene sterol ether and the polyoxyethylene stanol ether. Component B has a high affinity for component A and forms a bilayer with component A. Further, it is presumed that the curvature of the bilayer film is adjusted, thereby contributing to stabilization of the bicell structure. As component B, polyoxyethylene stanol ether is more preferred from the viewpoint of excellent oxidation stability.
  • the polyoxyethylene sterol ether or polyoxyethylene stanol ether is obtained by adding oxyethylene to sterol or stanol.
  • the average number of moles of oxyethylene to be added to sterol or stanol is 15 to 50, preferably 20 to 30.
  • Component B includes, for example, polyoxyethylene phytosterol ether, polyoxyethylene phytostanol ether, polyoxyethylene cholesterol ether, polyoxyethylene cholestanol ether and the like. Among them, vegetable polyoxyethylene phytosterol ether and polyoxyethylene phytostanol ether are preferred. As the component B, only one type may be used, or two or more types may be used.
  • ком ⁇ онент B a commercially available product may be used.
  • Examples of commercially available products of Component B include “NIKKOL @ BPS-20”, trade name “NIKKOL @ BPS-30”, and trade name “NIKKOL @ BPSH-25” (all manufactured by Nikko Chemicals Co., Ltd.).
  • the content ratio of the component B in the skin cosmetic composition of the present invention is not particularly limited, but is preferably 0.03% by mass or more based on 100% by mass of the total amount of the skin cosmetic composition of the present invention, It is more preferably at least 1.0% by mass. When the content is 0.03% by mass or more, it sufficiently contributes to stabilization of the bicell structure, and is further excellent in transparency and storage stability.
  • the upper limit of the content ratio is preferably 15.0% by mass or less, and more preferably 10.0% by mass or less. When the content ratio is 15.0% by mass or less, an excessive increase in viscosity can be suppressed, and the dispersibility can be further improved.
  • the content ratio of the component B is the sum of the content ratios of all the component B in the skin cosmetic composition of the present invention.
  • the mass ratio (B / A) of the component B to the component A in the skin cosmetic composition of the present invention is 5.5 or more, preferably 6.0 or more, more preferably 7.0 or more. Further, the mass ratio (B / A) is 18.0 or less, preferably 15.0 or less, more preferably 12.0 or less. When the mass ratio (B / A) is within the above range, transparency and storage stability are more excellent.
  • Component C is “a monovalent aliphatic alcohol having a branched chain and having 12 to 24 carbon atoms”. It is presumed that the use of Component C softens the lipid bilayer membrane and contributes to stabilization.
  • Component C includes, for example, octyldodecanol, decyltetradecanol, isostearyl alcohol and the like. Among them, octyldodecanol and decyltetradecanol are preferred from the viewpoint of improving storage stability. As the component C, only one type may be used, or two or more types may be used.
  • the content ratio of the component C in the skin cosmetic composition of the present invention is not particularly limited, but is preferably 0.005% by mass or more based on 100% by mass of the total amount of the skin cosmetic composition of the present invention. It is more preferably at least 0.05% by mass, and even more preferably at least 0.1% by mass. When the content is 0.005% by mass or more, the storage stability is further improved.
  • the upper limit of the content ratio is preferably 0.5% by mass or less, more preferably 0.4% by mass or less. When the content is 0.5% by mass or less, the transparency is further improved.
  • the content ratio of the component C is the sum of the content ratios of all the components C in the skin cosmetic composition of the present invention.
  • the mass ratio (C / A) of the component C to the component A in the skin cosmetic composition of the present invention is not particularly limited, but is preferably 0.05 or more, more preferably 0.1 or more, and still more preferably. 0.15 or more. When the mass ratio (C / A) is 0.05 or more, the storage stability is further improved.
  • the upper limit of the mass ratio (C / A) is preferably 1.0 or less, more preferably 0.7 or less, and even more preferably 0.5 or less. When the mass ratio (C / A) is 1.0 or less, transparency is further improved.
  • Component D is "one or more polyhydric alcohols selected from the group consisting of propylene glycol, dipropylene glycol and 1,3-butylene glycol".
  • Component D functions as a solvent for other components during production of the skin cosmetic composition.
  • an increase in the viscosity of the dispersion when other components are dispersed is suppressed, and the dispersibility is improved.
  • the component D only one type may be used, or two or more types may be used.
  • the content ratio of the component D in the skin cosmetic composition of the present invention is not particularly limited, but is preferably 0.25% by mass or more based on 100% by mass of the total amount of the skin cosmetic composition of the present invention. It is more preferably at least 3.0% by mass, and even more preferably at least 5.0% by mass.
  • the upper limit of the content is preferably 30.0% by mass or less, more preferably 25.0% by mass or less, and still more preferably 15.0% by mass or less. When the content is in the above range, transparency and storage stability are further improved.
  • the content ratio of the component D is the sum of the content ratios of all the components D in the skin cosmetic composition of the present invention.
  • the mass ratio (D / A) of the component D to the component A in the skin cosmetic composition of the present invention is not particularly limited, but is preferably 8.0 or more, more preferably 10.0 or more.
  • the upper limit of the mass ratio (D / A) is preferably 60.0 or less, more preferably 30.0 or less, and even more preferably 20.0 or less. When the mass ratio (D / A) is within the above range, the composition for skin cosmetics is more excellent in preventing cloudiness.
  • Component E is "water”. By using water, freshness and freshness can be imparted to the skin cosmetic composition of the present invention, and further the skin cosmetic composition of the present invention is applied to skin cosmetics such as aqueous lotions. be able to.
  • the content ratio of the component E in the skin cosmetic composition of the present invention is not particularly limited, but is preferably 55.0% by mass or more based on 100% by mass of the total amount of the skin cosmetic composition of the present invention. It is more preferably at least 60.0% by mass, still more preferably at least 65.0% by mass. The content is preferably 95.0% by mass or less, more preferably 90.0% by mass or less, and still more preferably 85.0% by mass or less. It is preferable that the compounding ratio be within the above range, since simplicity and a refreshing feeling upon application to an aqueous lotion can be obtained.
  • Component F is a "sterol”. Component F is presumed to adjust the curvature of the bilayer and thereby contribute to the stabilization of the bicell structure. In addition, it is also blended as an active ingredient for improving skin barrier function and the like.
  • the component F includes, for example, animal sterol, plant sterol (phytosterol) and the like.
  • Animal sterols include, for example, cholesterol, cholestanol, 7-dehydrocholesterol and the like.
  • Examples of the plant sterol include sitosterol, stigmasterol, fucosterol, spinasterol, and brassicasterol.
  • As the component F only one type may be used, or two or more types may be used.
  • component F a commercially available product can be used.
  • examples of commercial products of Component F include, for example, trade name “Cholesterol JSQI”, trade name “Cholesterol of Japanese Pharmacopoeia” (all manufactured by Nippon Seika Co., Ltd.), and trade name “phytosterol” (manufactured by Eisai Food Chemical Co., Ltd.) And the trade name "Phytosterol-SKP” (manufactured by Tama Seikagaku Co., Ltd.).
  • the content ratio of the component F in the skin cosmetic composition of the present invention is not particularly limited, but is preferably 0.01% by mass or more based on 100% by mass of the total amount of the skin cosmetic composition of the present invention, It is more preferably at least 0.1% by mass, further preferably at least 0.2% by mass. When the content is 0.01% by mass or more, a barrier function or the like can be imparted to the skin.
  • the upper limit of the content is preferably 2.0% by mass or less, more preferably 1.0% by mass or less, and even more preferably 0.6% by mass or less. When the mass ratio is 2.0% by mass or less, the storage stability is further improved.
  • the content ratio of the component F is the sum of the content ratios of all the components F in the skin cosmetic composition of the present invention.
  • Component G is “oil”.
  • Component G includes, for example, vegetable oil, ester oil, silicone oil, hydrocarbon oil, wax, higher fatty acid, higher alcohol other than component C, and the like.
  • Component G is used as an emollient component in the skin cosmetic composition of the present invention, for example, to prevent evaporation of skin moisture and to soften keratin.
  • the component G does not include the component F.
  • As the component G only one type may be used, or two or more types may be used.
  • Examples of the vegetable oil include macadamia nut oil, eucalyptus oil, coconut oil, avocado oil, safflower oil, olive oil, palm oil, palm kernel oil, kukui nut oil, shea butter (shea butter), cocoa butter, almond oil, and sunflower oil.
  • Rose hip oil olive squalane, camelia oil, kiwi fruit seed oil, camellia oil, apricot kernel oil, sesame oil, soybean oil, jojoba oil, castor oil, hazelnut oil, meadowfoam oil, peppermint oil, argan oil, carrot oil, lavender Oil, sugar squalane, damask rose flower wax, centifolia rose flower wax, scotch flower wax, camellia oil, hydrogenated products thereof (for example, hydrogenated castor oil, hydrogenated jojoba oil, hydrogenated palm oil, hydrogenated avocado oil, Hydrogenated soybean oil and the like).
  • ester oil examples include ethyl oleate, isopropyl myristate, isopropyl palmitate, myristyl myristate, cetyl palmitate, 2-ethylhexyl palmitate, octyl dodecyl myristate, isopropyl isostearate, propylene glycol isostearate, and propylene glycol isostearate.
  • silicone oil examples include, but are not particularly limited to, dimethyl silicone oil such as methylpolysiloxane and highly polymerized methylpolysiloxane; methylphenyl silicone oil such as methylphenylpolysiloxane; methylcyclopolysiloxane, octamethylcyclotetrasiloxane; Cyclic silicone oils such as decamethylcyclopentasiloxane and dodecamethylcyclohexasiloxane; aminopropylmethylsiloxane / dimethylsiloxane copolymer, aminoethylaminopropylsiloxane / dimethylsiloxane copolymer, aminoethylaminopropylmethylsiloxane / dimethylsiloxane Amino-modified silicone, carboxy-modified silicone, fatty acid-modified silicone, alcohol-modified silicone, aliphatic alcohol-modified silicone such as polymers Emissions, epoxy-
  • hydrocarbon oil examples include ⁇ -olefin oligomer, petrolatum, isoparaffin, light isoparaffin, light liquid isoparaffin, squalane, synthetic squalane, vegetable squalane, liquid isoparaffin, liquid paraffin, hydrogenated polyisobutene, hydrogenated (tetradecenyl / Methylpentadecene), isododecane and the like.
  • wax examples include carnauba wax, candelilla wax, beeswax, rice bran wax, shellac wax, whale wax, lanolin, sunflower seed wax and the like.
  • higher fatty acids examples include lauric acid, myristic acid, palmitic acid, stearic acid, isostearic acid, and oleic acid.
  • Examples of higher alcohols other than the above-mentioned component C include cetyl alcohol, stearyl alcohol, myristyl alcohol, oleyl alcohol and the like.
  • component G preferably contains a highly polar oil component. Further, the highly polar oil component more preferably has a sterol skeleton. When a highly polar oil component is contained as the component G, the emollient effect is further improved. As the highly polar oil, only one kind may be used, or two or more kinds may be used.
  • any of plant-derived, animal-derived, and mineral-derived oils can be used.
  • polar fats and oils include hydrogenated palm oil, hydrogenated jojoba oil, shea butter, (adipic acid / 2-ethylhexanoic acid / stearic acid) glyceryl oligoester, macadamia nut oil fatty acid phytosteryl, glyceryl tricaprylate, glyceryl tricaprate, Glyceryl trimyristate, glyceryl tristearate, phytosteryl oleate, dipentaerythrityl hydroxystearate, dipentaerythrityl stearate, dipentaerythrityl rosinate, dipentaerythrityl hexahydroxystearate, and the like.
  • Phytosteryl oleate is preferred from the viewpoint of further enhancing the emollient effect of the skin cosmetic composition of the present invention.
  • the content ratio of the component G in the skin cosmetic composition of the present invention is not particularly limited, but is preferably 0.01% by mass or more based on 100% by mass of the total amount of the skin cosmetic composition of the present invention. More preferably, it is 0.05% by mass or more. When the content is 0.01% by mass or more, emollient effects such as moisturizing and keratin softening are further exhibited.
  • the content is preferably 0.3% by mass or less, more preferably 0.2% by mass or less. When the content is 0.3% by mass or less, the storage stability is further improved.
  • the content ratio of the component G is the sum of the content ratios of all the components G in the skin cosmetic composition of the present invention.
  • the mass ratio (G / A) of the component G to the component A in the skin cosmetic composition of the present invention is not particularly limited, but is preferably 0.01 or more, more preferably 0.02, and still more preferably. Is 0.05 or more.
  • the mass ratio (G / A) is preferably 1.0 or less, more preferably 0.8 or less, and even more preferably 0.5 or less. When the mass ratio (G / A) is within the above range, the storage stability is more excellent.
  • Component H is "polyoxyethylene hydrogenated castor oil having an average addition mole number of oxyethylene of 5 to 30". Component H is presumed to adjust the curvature of the bilayer in the skin cosmetic composition of the present invention, thereby contributing to stabilization of the bicell structure. In particular, it exerts an effect of stably confining the component G in the film and improving storage stability. As the component H, only one type may be used, or two or more types may be used.
  • the average number of moles of oxyethylene added as the component H is 5 to 30.
  • the average number of moles added is preferably 10 or more, more preferably 15 or more, and preferably 25 or less.
  • the oil component is more stably confined in the bicell, and the effect of increasing the storage stability is further exhibited.
  • the component H is most preferably a polyoxyethylene hydrogenated castor oil having an average addition number of oxyethylene of 20.
  • the HLB (Hydrophil-Lipophile Balance) value of the component H is not particularly limited, but is, for example, 6.0 to 11.0, and preferably 6.5 to 10.5.
  • Use of the component H having an HLB value in the above range contributes to storage stability. The more the HLB value of the component H indicates lipophilicity, the better the storage stability. Note that the HLB value can be calculated by the Griffin method.
  • the content ratio of the component H in the skin cosmetic composition of the present invention is not particularly limited, but is preferably 0.05% by mass or more based on 100% by mass of the total amount of the skin cosmetic composition of the present invention. It is more preferably at least 0.5% by mass.
  • the content is preferably 5.0% by mass or less, more preferably 3.0% by mass or less, and further preferably 2.0% by mass or less. When the content is within the above range, the effect of stably confining the component G in the lipid bilayer membrane is more excellent.
  • the content ratio of the component H is the sum of the content ratios of all the component Hs in the skin cosmetic composition of the present invention.
  • Component I is "glycerin mono 2-ethylhexyl ether” (also referred to as “octoxyglycerin”). When component I is contained, it is presumed that flexibility is imparted to the membrane shape because it penetrates into the bicellular lipid bilayer membrane. For this reason, the composition for skin cosmetics of the present invention further improves transparency and storage stability.
  • the content ratio of Component I in the skin cosmetic composition of the present invention is not particularly limited.
  • the amount is preferably 0.01% by mass or more, more preferably 0.05% by mass or more, and still more preferably 0.1% by mass or more, based on the total amount of 100% by mass.
  • the upper limit of the content ratio is preferably 2.0% by mass or less, more preferably 1.5% by mass or less, and further preferably 1.0% by mass or less. (4) When the content is 2.0% by mass or less, a less irritating agent can be obtained.
  • Component J is "1,2-alkanediol having 5 to 10 carbon atoms".
  • component J is contained, it is presumed that flexibility is imparted to the membrane shape because it enters the bilayer lipid bilayer membrane. For this reason, the composition for skin cosmetics of the present invention further improves transparency and storage stability.
  • component J for example, 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, 1,2-decanediol and the like can be mentioned.
  • component J only one type may be used, or two or more types may be used.
  • the content ratio of the component J in the skin cosmetic composition of the present invention is not particularly limited.
  • the amount is preferably 0.01% by mass or more, more preferably 0.1% by mass or more, and still more preferably 0.2% by mass or more based on the total amount of 100% by mass.
  • the upper limit of the content is preferably 2.0% by mass or less, more preferably 1.0% by mass or less, and even more preferably 0.7% by mass or less.
  • the content ratio of the component J is the sum of the content ratios of all the components J in the skin cosmetic composition of the present invention.
  • the skin cosmetic composition of the present invention may further contain other components other than the above components A to J.
  • the other components are not particularly limited, but include, for example, surfactants other than component H (cationic surfactant, anionic surfactant, nonionic surfactant, amphoteric surfactant, etc.), lower alcohols, other than component C Higher alcohols, polyhydric alcohols other than component D, ultraviolet absorbers, powders, antioxidants, preservatives, fragrances, coloring agents, chelating agents, cooling agents, thickeners, vitamins, neutralizing agents, amino acids, Additives such as pH adjusters, whitening agents, anti-inflammatory agents, deodorants, plant and animal extracts, sequestering agents, and the like. As the other components, only one kind may be used, or two or more kinds may be used.
  • the skin cosmetic composition of the present invention preferably has a transparent appearance from the viewpoint of aesthetics. Further, the high transparency of the composition for skin cosmetics of the present invention means that the incorporated oil does not agglomerate or cream, and indicates that the composition is in a very stable state. For this reason, the transparency of the skin cosmetic composition of the present invention also serves as an index of storage stability.
  • component A forms a bicellular structure which is a form of micelle.
  • the bicell structure is a disk-shaped lipid bilayer composed of phospholipids.
  • the bicellular structure in the skin cosmetic composition of the present invention has a particle size of about 20 to 50 nm, which is between micelles and liposomes.
  • an oil component can be compounded in the lipid bilayer membrane, a larger amount of oil component can be compounded than a micelle.
  • it since it does not have the particle size of liposomes, it has excellent storage stability. Further, with the bicell structure, transparency is not impaired.
  • the skin cosmetic composition of the present invention is preferably a skin cosmetic composition that does not contain liposomes formed from phospholipids.
  • the pH of the skin cosmetic composition of the present invention is not particularly limited, but is preferably, for example, 5.0 to 8.0 at 25 ° C.
  • the viscosity of the composition for skin cosmetics of the present invention is not particularly limited.
  • the viscosity at 25 ° C. is preferably 0.5 to 1000 mPa ⁇ s, and more preferably 0.5 to 500 mPa ⁇ s. More preferred.
  • the viscosity is measured at a rotational speed of 60 r / min by using a B-type viscometer, selecting a rotor suitable for the viscosity.
  • the average particle size of the bicell structure of the skin cosmetic composition of the present invention is not particularly limited, but is preferably 20 nm or more, more preferably 30 nm or more, and further preferably 40 nm or more.
  • the upper limit of the average particle diameter is preferably 100 nm or less, more preferably 90 nm or less, and still more preferably 80 nm or less.
  • the upper limit of the average particle diameter is 100 nm or less, the storage stability and the transparency are more excellent.
  • the above average particle diameter (nm) can be measured using a dynamic light scattering photometer or a transmission electron microscope (TEM).
  • the composition can be produced by mixing the above-mentioned components and stirring with a known method, for example, using a homomixer.
  • the composition for skin cosmetics of the present invention can be used as a raw material (so-called intermediate raw material) used in the production of skin cosmetics.
  • the composition for skin cosmetics of the present invention can be stably dispersed in an aqueous or low-viscosity dispersion medium, so that the component G can be incorporated into the skin cosmetics.
  • the composition for skin cosmetics of the present invention can be used as a skin cosmetic as such.
  • a skin cosmetic containing the above-described composition for skin cosmetic of the present invention is obtained.
  • skin cosmetic containing the composition for skin cosmetics of the present invention may be referred to as “skin cosmetic of the present invention”.
  • the content of the skin cosmetic composition of the present invention in 100% by mass of the skin cosmetic of the present invention is not particularly limited, but is preferably 0.1 to 100% by mass, more preferably 0.5 to 10.0%. % By mass.
  • the dosage form of the composition for skin cosmetics (or skin cosmetics) of the present invention is not particularly limited, and examples thereof include lotions (creams), gels, emulsions, aerosol sprays, natural sprays, sticks, powders, and the like.
  • Various dosage forms such as roll-on, sheet (paper) and the like can be mentioned.
  • lotions (lotions), creams, gels and emulsions are preferable, and lotions (lotions) are more preferable.
  • the skin cosmetic composition (or skin cosmetic) of the present invention are not particularly limited, and include, for example, moisturizing cosmetics, whitening cosmetics, acne care cosmetics, and anti-aging cosmetics (eg, wrinkle suppression, sagging suppression) Skin care cosmetics (for the purpose of, etc.); scalp care cosmetics (for the purpose of moisturizing, suppressing sebum, etc.); deodorant cosmetics; sunscreen cosmetics; shaving cosmetics; Body shampoo, bar soap, etc.)
  • the skin cosmetic composition (or skin cosmetic) of the present invention is preferably a skin care cosmetic or a scalp care cosmetic, and more preferably a skin care cosmetic.
  • the skin cosmetic composition (or skin cosmetic) of the present invention may be, for example, any of cosmetics, quasi-drugs, pharmaceuticals, and miscellaneous goods.
  • the site to which the skin cosmetic composition (or skin cosmetic) of the present invention is applied is not particularly limited, and may include a face (for example, forehead, eyes, eyes, cheeks, mouth, etc.), arm, elbow, back of hand, fingertip. , Feet, knees, heels, neck, sides, back, scalp and the like.
  • the composition for skin cosmetics of the present invention is a skin cosmetic composition containing water (component E) as a medium, wherein the average addition mole number of phospholipid (component A) and oxyethylene is 15 to 50.
  • Polyoxyethylene stanol ether having an average addition mole number of ether and / or oxyethylene of 15 to 50 (component B), a monovalent aliphatic alcohol having a branched chain having 12 to 24 carbon atoms (component C), propylene glycol,
  • One or more polyhydric alcohols selected from the group consisting of dipropylene glycol and 1,3-butylene glycol (component D), sterols (component F), oils (component G), and an average number of moles of added oxyethylene of 5 to 5 Contains 30 polyoxyethylene hydrogenated castor oil (Component H).
  • the bicellular structure in the skin cosmetic composition of the present invention is composed of component B, component C, component F, component G, and component H, with component A as the center.
  • Component D functions as a solvent for other components during production.
  • component B, component F, and component H adjust the curvature of the lipid bilayer
  • component C contributes to the flexibility of the lipid bilayer.
  • stability of the bicell structure is particularly improved.
  • blending of component G tends to destabilize the bicell structure, but in the present invention, in particular, by including component H as a component of the lipid bilayer, the bicomponent structure can be contained in the lipid bilayer.
  • the feature is that G can be stably compounded.
  • the bicellular structure in the skin cosmetic composition of the present invention has a particle size of about 20 to 50 nm, which is between micelles and liposomes.
  • the component G can be compounded in the lipid bilayer membrane, more components G can be compounded than the micelle.
  • it since it does not have the particle size of liposomes, it has excellent storage stability. Further, if the particle size is within the above range, transparency is not impaired.
  • the skin cosmetic composition of the present invention can be excellent in transparency and storage stability while being an aqueous skin cosmetic composition containing an oil having an emollient effect.
  • the compounding amount described in the table is the compounding amount of each component (that is, the compounding amount of the active ingredient in each raw material; so-called pure content), and is represented by "% by mass” unless otherwise specified.
  • Hydrogenated lecithin hydrogenated soybean lecithin
  • Polyoxyethylene phytostanol trade name "NIKKOL BPSH-25", manufactured by Nikko Chemicals Co., Ltd., POE-25 phytostanol polyoxyethylene phytosterol A: trade name "NIKKOL BPS-20", Nikko Chemicals Co., Ltd., POE-20 phytosterol polyoxyethylene phytosterol B: trade name "NIKKOL BPS-30", Nikko Chemicals Co., Ltd., POE-30 phytosterol polyoxyethylene phytosterol C: trade name "NIKKOL BPS-5", Nikko POE-5 phytosterol polyoxyethylene phytosterol D manufactured by Chemicals Co., Ltd .: trade name "NIKKOL BPS-10", POE-10 phyto manufactured by Nikko Chemicals Co., Ltd.
  • Sterol Sterol Phytosterol Polyoxyethylene-hardened castor oil A: Trade name "EMALEX HC-20", manufactured by Nippon Emulsion Co., Ltd., PEG-20 hydrogenated castor oil, HLB: 9.0 Polyoxyethylene hydrogenated castor oil B: trade name "Brownon RCW-40", manufactured by Aoki Yushi Kogyo KK, PEG-40 hydrogenated castor oil, HLB: 12.5 Polyoxyethylene hydrogenated castor oil C: trade name "Brownon RCW-50", manufactured by Aoki Yushi Kogyo KK, PEG-50 hydrogenated castor oil, HLB: 13.5 Polyethylene glycol monostearate: trade name "MYS-40V”, manufactured by Nikko Chemicals Co., Ltd., PEG-40 stearate
  • Comparative Example 1 which lacks any of the components A, B, F, and H, can separate, precipitate, or precipitate under any of low-temperature storage (5 ° C.) and high-temperature storage (40 ° C.).
  • Comparative Examples 1 to 3 which lack the components A, B, or F, which are the main components of the bicellular bilayer membrane, it is presumed that the bicell structure itself was not formed.
  • component H polyoxyethylene hydrogenated castor oil having a specific number of moles of oxyethylene added
  • Comparative Examples 4 to 10 lacking this did not stabilize the bicell structure and collapsed. It is supposed to be.
  • Comparative Example 11 when the B / A value was outside the range specified in the present invention, the storage stability at low and high temperatures was poor.
  • the skin cosmetic composition of the present invention it is possible to provide a skin cosmetic composition which can contain a relatively large amount of oil and is excellent in transparency and storage stability.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cosmetics (AREA)

Abstract

L'invention concerne une composition cosmétique destinée à la peau capable de présenter une quantité relativement grande d'huile, et possédant une excellente transparence et une excellente stabilité au stockage. La composition cosmétique destinée à la peau contient un constituant A, un constituant B, un constituant C, un constituant D, un constituant E, un constituant F, un constituant G et un constituant H. Le rapport de masse (B/A) du constituant B sur le constituant A est compris entre 5,5 et 18,0. Le constituant A est un phospholipide ; le constituant B est un polyoxyéthylène stérol éther comportant en moyenne de 15 à 50 moles d'oxyéthylène ajoutées à ce dernier et/ou un éther de polyoxyéthylène stanol comportant en moyenne de 15 à 50 moles d'oxyéthylène ajoutées à ce dernier ; le constituant C est un alcool aliphatique monovalent en C12-C24 comportant une chaîne ramifiée ; le constituant D est au moins un type d'alcool polyvalent sélectionné dans le groupe constitué par le propylène glycol, le dipropylène glycol et le 1,3-butylène glycol ; le constituant E est de l'eau ; le constituant F est un stérol ; le constituant G est une huile ; et le constituant H est de l'huile de ricin hydrogénée polyoxyéthylénée possédant en moyenne de 5 à 30 moles d'oxyéthylène ajoutées à cette dernière.
PCT/JP2019/036973 2018-09-28 2019-09-20 Composition cosmétique destinée à la peau Ceased WO2020066895A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CN201980043706.7A CN112351768A (zh) 2018-09-28 2019-09-20 皮肤化妆料用组合物
KR1020207037364A KR102532929B1 (ko) 2018-09-28 2019-09-20 피부 화장료용 조성물
JP2020549123A JP6982697B2 (ja) 2018-09-28 2019-09-20 皮膚化粧料用組成物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018185189 2018-09-28
JP2018-185189 2018-09-28

Publications (1)

Publication Number Publication Date
WO2020066895A1 true WO2020066895A1 (fr) 2020-04-02

Family

ID=69951996

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2019/036973 Ceased WO2020066895A1 (fr) 2018-09-28 2019-09-20 Composition cosmétique destinée à la peau

Country Status (4)

Country Link
JP (1) JP6982697B2 (fr)
KR (1) KR102532929B1 (fr)
CN (1) CN112351768A (fr)
WO (1) WO2020066895A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022202880A1 (fr) * 2021-03-25 2022-09-29 株式会社カネカ Disque bicouche lipidique et son procédé de production

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102618004B1 (ko) * 2023-03-28 2023-12-27 (주)삼경코스텍 난용성 유효 성분이 안정화 된 천연 유래 테르펜 글리코사이드 함유 바이셀 구조체 및 이의 제조방법

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003267830A (ja) * 2002-03-15 2003-09-25 Kose Corp 液状化粧料
JP2012092021A (ja) * 2010-10-25 2012-05-17 Fancl Corp 水中油型乳化組成物
JP2014193823A (ja) * 2013-03-28 2014-10-09 Kose Corp 化粧料
WO2017090740A1 (fr) * 2015-11-26 2017-06-01 株式会社コーセー Composition contenant une structure bicellulaire
JP2017178936A (ja) * 2016-03-29 2017-10-05 株式会社コーセー 化粧料
WO2018061854A1 (fr) * 2016-09-28 2018-04-05 株式会社マンダム Composition pour produit cosmétique

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05286824A (ja) 1992-04-08 1993-11-02 Kanegafuchi Chem Ind Co Ltd リポソーム含有化粧料
JPH11262653A (ja) 1998-03-17 1999-09-28 Nof Corp 水中油型マイクロエマルションおよびそれを含有する化粧料
JP4406498B2 (ja) * 2000-07-10 2010-01-27 ライオン株式会社 皮膚化粧料
CN102238934B (zh) * 2008-12-03 2014-10-29 株式会社资生堂 一种水包油型化妆品
JP2010235491A (ja) * 2009-03-31 2010-10-21 Nof Corp 化粧料用リポソーム
JP5074637B2 (ja) * 2010-10-29 2012-11-14 株式会社コーセー ベシクル組成物、それを含有する皮膚外用剤及び化粧料
CN107920553A (zh) * 2015-06-11 2018-04-17 阿彻丹尼尔斯米德兰德公司 卵磷脂组合物及制备和使用此种卵磷脂组合物的方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003267830A (ja) * 2002-03-15 2003-09-25 Kose Corp 液状化粧料
JP2012092021A (ja) * 2010-10-25 2012-05-17 Fancl Corp 水中油型乳化組成物
JP2014193823A (ja) * 2013-03-28 2014-10-09 Kose Corp 化粧料
WO2017090740A1 (fr) * 2015-11-26 2017-06-01 株式会社コーセー Composition contenant une structure bicellulaire
JP2017178936A (ja) * 2016-03-29 2017-10-05 株式会社コーセー 化粧料
WO2018061854A1 (fr) * 2016-09-28 2018-04-05 株式会社マンダム Composition pour produit cosmétique

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022202880A1 (fr) * 2021-03-25 2022-09-29 株式会社カネカ Disque bicouche lipidique et son procédé de production

Also Published As

Publication number Publication date
JP6982697B2 (ja) 2021-12-17
JPWO2020066895A1 (ja) 2021-04-01
KR102532929B1 (ko) 2023-05-16
CN112351768A (zh) 2021-02-09
KR20210015907A (ko) 2021-02-10

Similar Documents

Publication Publication Date Title
JP7020941B2 (ja) 化粧料
JP7084164B2 (ja) 難溶性成分を含有する化粧料
JP2017155034A (ja) 低分子シリコーン代替油剤
JP2021147342A (ja) 水中油型乳化組成物
CN1723872B (zh) 水包油型乳化组合物
JP5623773B2 (ja) 水中油型乳化組成物
KR102381622B1 (ko) 쌀겨왁스의 안정화 방법 및 고 함량의 쌀겨왁스를 안정화한 나노에멀젼을 함유하는 화장료 조성물
JP6632735B2 (ja) 化粧料用組成物
JP6982697B2 (ja) 皮膚化粧料用組成物
JP7148252B2 (ja) 皮膚外用剤又は化粧料
JPWO2017179356A1 (ja) 過脂肪剤およびパーソナルケア組成物
JP7682661B2 (ja) 水中油型乳化組成物
JP2025124783A (ja) 水中油型乳化化粧料
JPWO2018180316A1 (ja) 乳化化粧料
JP6747763B2 (ja) 乳化化粧料
JP2019073462A (ja) 水中油型乳化皮膚洗浄料
JP6674878B2 (ja) 乳化化粧料
JP7546113B1 (ja) 水中油型乳化化粧料
JP2023152863A (ja) 皮膚化粧料用組成物
JP2020147538A (ja) 乳液状皮膚化粧料
WO2020227909A1 (fr) Émulsion eau-dans-huile à rupture rapide améliorée
JP7309400B2 (ja) 乳化化粧料組成物
JP2020164447A (ja) 乳化組成物
EP3582746B1 (fr) Lotion cosmétique
JP2025125590A (ja) 化粧水

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 19867642

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2020549123

Country of ref document: JP

Kind code of ref document: A

ENP Entry into the national phase

Ref document number: 20207037364

Country of ref document: KR

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 19867642

Country of ref document: EP

Kind code of ref document: A1