[go: up one dir, main page]

WO2019233367A8 - Souche de streptomyces et son application dans la production de staurosporine - Google Patents

Souche de streptomyces et son application dans la production de staurosporine Download PDF

Info

Publication number
WO2019233367A8
WO2019233367A8 PCT/CN2019/089782 CN2019089782W WO2019233367A8 WO 2019233367 A8 WO2019233367 A8 WO 2019233367A8 CN 2019089782 W CN2019089782 W CN 2019089782W WO 2019233367 A8 WO2019233367 A8 WO 2019233367A8
Authority
WO
WIPO (PCT)
Prior art keywords
staurosporine
application
production
streptomyces strain
strain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2019/089782
Other languages
English (en)
Chinese (zh)
Other versions
WO2019233367A1 (fr
Inventor
方佳双
张辉
项仁鑫
邓爱文
王微芬
应灵萍
姜南
王继栋
滕云
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhejiang Hisun Pharmaceutical Co Ltd
Original Assignee
Zhejiang Hisun Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zhejiang Hisun Pharmaceutical Co Ltd filed Critical Zhejiang Hisun Pharmaceutical Co Ltd
Publication of WO2019233367A1 publication Critical patent/WO2019233367A1/fr
Publication of WO2019233367A8 publication Critical patent/WO2019233367A8/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/46—Streptococcus ; Enterococcus; Lactococcus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L'invention concerne une souche de streptomyces et son application, et un procédé de préparation de staurosporine par culture de la souche. La souche est nommée streptomyces sp. HS-HY-153, et son numéro de conservation est CGMCC NO. 14806.
PCT/CN2019/089782 2018-06-04 2019-06-03 Souche de streptomyces et son application dans la production de staurosporine Ceased WO2019233367A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201810572019.1A CN108676757B (zh) 2018-06-04 2018-06-04 一株链霉菌属菌株及其产星孢菌素的应用
CN201810572019.1 2018-06-04

Publications (2)

Publication Number Publication Date
WO2019233367A1 WO2019233367A1 (fr) 2019-12-12
WO2019233367A8 true WO2019233367A8 (fr) 2020-09-10

Family

ID=63809976

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2019/089782 Ceased WO2019233367A1 (fr) 2018-06-04 2019-06-03 Souche de streptomyces et son application dans la production de staurosporine

Country Status (2)

Country Link
CN (1) CN108676757B (fr)
WO (1) WO2019233367A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108676757B (zh) * 2018-06-04 2020-08-11 浙江海正药业股份有限公司 一株链霉菌属菌株及其产星孢菌素的应用
KR102235779B1 (ko) * 2019-06-19 2021-04-01 국립해양생물자원관 해수로부터 분리된 스트렙토마이세스 속의 snc087 균주, 동 균주를 이용한 스타우로스포린의 생산방법, 동 균주의 배양방법 및 동 균주의 순수배양액
CN110642872B (zh) * 2019-11-18 2020-12-22 湖北宏中药业股份有限公司 一种星孢菌素提取方法
CN113122591B (zh) * 2019-12-30 2022-11-22 上海医药工业研究院 一种发酵生产星孢菌素的方法
CN111296417B (zh) * 2020-04-01 2021-04-20 广东省农业科学院植物保护研究所 一种星·甲维悬浮剂及其制备方法与应用
CN111793618A (zh) * 2020-08-05 2020-10-20 广东新达瑞生物科技有限公司 一种星孢菌素产生菌的选育及制备方法
CN112048530B (zh) * 2020-09-08 2021-10-29 浙江海正药业股份有限公司 一种促进星孢菌素积累的方法
CN112746036B (zh) * 2020-12-08 2021-08-24 浙江珲达生物科技有限公司 一种链霉菌及其发酵产假尿苷的方法
CN115806913B (zh) * 2022-10-21 2023-09-08 福建省农业科学院植物保护研究所 野尻链霉菌（Streptomyces nojiriensis）菌株9-13及应用
CN116144538B (zh) * 2022-12-30 2024-04-26 西南大学 一种可防治根肿病的黄暗色链霉菌及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7608420B2 (en) * 2003-04-22 2009-10-27 Lonza Ag Process for the recovery of staurosporine from a fermentation broth
KR20100069073A (ko) * 2008-12-16 2010-06-24 한국해양연구원 스타우로스포린을 생산하는 미생물 및 이를 이용한 스타우로스포린 제조방법
CN107603922B (zh) * 2017-11-06 2019-10-18 海南大学 海绵共生链霉菌及其发酵生产星形孢菌素的方法和应用
CN108048369B (zh) * 2018-01-26 2020-06-19 中国医学科学院医药生物技术研究所 一种产星形孢菌素的海洋链霉菌及其制备方法
CN108676757B (zh) * 2018-06-04 2020-08-11 浙江海正药业股份有限公司 一株链霉菌属菌株及其产星孢菌素的应用

Also Published As

Publication number Publication date
WO2019233367A1 (fr) 2019-12-12
CN108676757A (zh) 2018-10-19
CN108676757B (zh) 2020-08-11

Similar Documents

Publication Publication Date Title
WO2019233367A8 (fr) Souche de streptomyces et son application dans la production de staurosporine
AU2018293281A1 (en) Novel aspartokinase mutant and method for production of L-amino acid using same
MY172431A (en) Microalgae of the genus euglena, method for producing polysaccharides, and method for producing organic compound
EP4477393A3 (fr) Formage a double diaphragme de materiaux composites, ensembles pour un tel formage et materiaux composites obtenus
MY205372A (en) Imp-producing microorganism and method of producing imp using the same
MY198467A (en) L-Threonine Export Protein Variant and Method for Production of L-Threonine Using Same
WO2018124440A3 (fr) Nouveau mutant de l'isopropylmalate synthase et procédé de production de l-leucine faisant appel à celui-ci
PH12020500115A1 (en) cAMP RECEPTOR PROTEIN VARIANT AND METHOD OF PRODUCING L-AMINO ACID USING THE SAME
MX2021004610A (es) Variante proteica receptora de ampc y procedimiento de produccion de l-aminoacido mediante el uso de la misma.
WO2019124932A3 (fr) Micro-organisme corynebacterium sp produisant de la l-arginine, et procédé de production de l-arginine l'utilisant
ZA202206643B (en) Mutant of inner membrane protein, and method for producing target product by using same
MY184142A (en) Microorganisms for producing putrescine or ornithine and process for producing putrescine or ornithine using them
PH12020550976A1 (en) Camp receptor protein variant and method of producing l-amino acid using the same
PH12019500096A1 (en) Leuconostoc mesenteroides cjlm119 strain producing reduced amount of gas, and kimchi production method using same
AR100101A1 (es) Cepas de streptomyces microflavus y métodos de uso de las mismas para controlar enfermedades y plagas en plantas
EP4039796A4 (fr) Procédé de production de composition pour la culture cellulaire, composition pour la culture cellulaire obtenue par ce dernier, et procédé de culture cellulaire l'utilisant
WO2019017706A3 (fr) Micro-organisme produisant de la putrescine et procédé de production de putrescine l'utilisant
WO2023009529A3 (fr) Nouveaux polypeptides et leurs utilisations
WO2018131898A3 (fr) Nouvelle utilisation de souche de méthylomonas sp. dh-1
WO2019004779A3 (fr) Nouveau mutant transférase o-succinylhomosérine et procédé de production d'o-succinylhomosérine utilisant ce dernier
PH12020550834A1 (en) Fermented soybean composition and method for producing fermented soybean composition
WO2020074569A8 (fr) Compositions comprenant des souches bactériennes
MY188407A (en) Novel lactobacillus sp. microorganisms, and composition for animal feed comprising same
PH12022550820A1 (en) Yeast strain producing glutathione and method of producing glutathione using the same
MY210258A (en) Microorganism of the genus corynebacterium producing 5'-xanthosine monophosphate and method for preparing 5'-xanthosine monophosphate using the same

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 19814029

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 19814029

Country of ref document: EP

Kind code of ref document: A1