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WO2019153966A1 - Appareil d'éclairage pour réguler les rythmes biologiques humains - Google Patents

Appareil d'éclairage pour réguler les rythmes biologiques humains Download PDF

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Publication number
WO2019153966A1
WO2019153966A1 PCT/CN2018/125525 CN2018125525W WO2019153966A1 WO 2019153966 A1 WO2019153966 A1 WO 2019153966A1 CN 2018125525 W CN2018125525 W CN 2018125525W WO 2019153966 A1 WO2019153966 A1 WO 2019153966A1
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WO
WIPO (PCT)
Prior art keywords
light
human body
emitting unit
parameter
modulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2018/125525
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English (en)
Chinese (zh)
Inventor
马君显
马捷
曾义芳
明瑞波
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyselife Tech Ltd Shenzhen
Original Assignee
Wyselife Tech Ltd Shenzhen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyselife Tech Ltd Shenzhen filed Critical Wyselife Tech Ltd Shenzhen
Publication of WO2019153966A1 publication Critical patent/WO2019153966A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0618—Psychological treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0622—Optical stimulation for exciting neural tissue
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B45/00—Circuit arrangements for operating light-emitting diodes [LED]
    • H05B45/20—Controlling the colour of the light
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B45/00—Circuit arrangements for operating light-emitting diodes [LED]
    • H05B45/30—Driver circuits
    • H05B45/37—Converter circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0635—Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0643—Applicators, probes irradiating specific body areas in close proximity
    • A61N2005/0645—Applicators worn by the patient
    • A61N2005/0647—Applicators worn by the patient the applicator adapted to be worn on the head
    • A61N2005/0648—Applicators worn by the patient the applicator adapted to be worn on the head the light being directed to the eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/065—Light sources therefor
    • A61N2005/0657—Natural light sources, e.g. captured sunlight

Definitions

  • Illumination device for regulating human biological rhythm
  • the present invention relates to the field of medical or healthcare equipment, and more particularly to an illumination device that regulates the biological rhythm of a human body.
  • ipRGCs Intrinsically photosensitive retinal ganglion cells
  • the former mainly transmits visual light signals to the brain to form visual images, colors and their Changes, while the latter mainly transmits non-visual light signals to the pineal gland of the hypothalamus to participate in the regulation of the circadian clock, thereby producing an adjustment effect on the physiological and mental health of the human body.
  • 5 See the technology, there are some special devices or device systems that use light to control diseases or regulate biological rhythms. Although the technical forms and device forms are different, but the blue light stimulates the human eye to adjust the human body clock. . 5 See that these devices in the technology may also have certain effects, but it is undeniable that the defects are also obvious, for example, only by the light intensity and the illumination time to control the sum of the intensity of the emitted light and the illumination indiscriminately.
  • the technical problem to be solved by the present invention is that, in view of the existing technology, it is impossible to adjust the illumination parameters due to human factors, the biological rhythm cannot be finely adjusted, the adjustment effect is not verified, and the safety factor is not high.
  • the invention provides an illumination device with a regulation effect feedback mechanism, which can realize the fine adjustment of the biological rhythm effect through the illumination parameter and has high safety, and adjusts the human biological rhythm.
  • the technical solution adopted by the present invention to solve the technical problem thereof is: constructing an illumination device for adjusting a human biological rhythm, comprising: a bracket worn on a human body, a control unit disposed on the bracket, and a light emitting unit, The control unit outputs a control signal to the light-emitting unit, and controls a light parameter of the light-emitting unit to emit light; the light-emitting unit is disposed at a set position of the bracket, and controls the output of the light-emitting unit according to the output of the control unit
  • the light produced by the signal forms a bundle of rays and is projected onto a non-visual area of the human body wearing the stent.
  • the non-vision area includes an area unrelated to imaging and a region around the eye in the pupil of the human body;
  • the light parameters include: a central wavelength and a spectral component thereof, a light intensity, a spectral power density, and a light intensity
  • control unit includes a parameter acquisition module and a modulation module
  • the parameter acquisition module selects the optical parameter and forms a modulation signal to be transmitted to the modulation module
  • the modulation module uses the modulation signal pair
  • the driving signal of the light emitting unit is modulated to obtain a modulated optical driving signal and transmitted to the light emitting unit, and the light emitting unit is driven to emit light that conforms to the light parameter.
  • control unit further includes a communication module, and the communication module receives the set component of the brain wave of the human body that is currently detected and processed by the external device and uses the illumination device that adjusts the biological rhythm of the human body.
  • the parameter is transmitted to the parameter acquisition module as a basis for the parameter acquisition module to select the optical parameter.
  • a parameter of a component is set in the brain wave, such as but not limited to a frequency value of (3 wave or Y wave), and the parameter obtaining module makes the parameter in the parameter when the light parameter is selected.
  • the time modulation frequency of the light intensity is close to or equal to the frequency corresponding to the received maximum power spectral density of the 3 or Y wave.
  • the light emitting unit includes a plurality of set positions respectively disposed on the bracket; a pointing area where each of the light emitting units emits light is determined by a position of the light emitting unit and a structure of the light emitting unit itself.
  • the light emitting unit includes at least one light group, each light group including at least one LED and an optical structure that focuses light emitted by the LEDs in the light group to form a nearly parallel light beam; The mounting position and angle determine the angle at which the beam is directed.
  • the lamp group includes a red LED, a yellow LED, and a green light having different light wavelengths, which are uniformly distributed around the axial position of the optical structure and respectively driven by different modulated driving signals. led
  • the plurality of lamp groups are respectively driven by different driving signals, and the superposition of the plurality of driving signals is restricted by the control signals output by the control unit.
  • the bracket includes a glasses holder, and the light emitting unit is disposed on an upper edge or a lower edge of an intermediate position in a width direction of the lens frame of the eyeglass holder, and has a set angle, so that the The light beam emitted by the light unit is directed to the non-visual area of the pupil corresponding to the position.
  • An illumination device for adjusting a human body rhythm of the present invention has the following beneficial effects: Since the control unit is used to control the light emitted by the light emitting unit, and the control unit is capable of selecting the light parameter, The key parameters such as the light intensity of the emitted light, the center frequency, and the like can be selected one by one, thereby forming a light whose characteristics are composed of a plurality of parameters, so that the effect of using the light is better, and the control of the light is controlled. It is easier; at the same time, since the illumination area is limited to the non-visual area, the safety can be greatly improved without affecting the effect, and the visual acuity of the user is not affected.
  • FIG. 1 is a schematic structural view of an apparatus for illuminating a human body biological rhythm according to an embodiment of the present invention
  • FIG. 2 is a schematic view showing the position of an LED in a lamp group in the embodiment
  • FIG. 3 is a side view showing the position of the lamp group and the pupil in the embodiment
  • FIG. 4 is a front elevational view showing the position of the lamp group and the pupil in the embodiment
  • FIG. 5 is a schematic view showing a light beam structure of a lamp group in the embodiment
  • FIG. 6 is a schematic structural diagram of a function module of the device in the embodiment.
  • the illumination device for adjusting a human biological rhythm comprises a bracket 16 worn on a human body, and is disposed on the bracket.
  • Control unit (10, 11, 12) and lighting unit ie, lamp group 1, lamp group 2, lamp group 3, lamp group 4, lamp group 5, lamp group 6, lamp group 7, lamp group 8
  • the control unit outputs a control signal to the light emitting unit, and controls a light parameter of the light emitting unit to emit light; the light emitting unit is disposed at a set position of the bracket 16, and is issued by the control unit
  • the light produced by the output control signal forms a bundle of rays and is projected onto a non-visual area of the human body wearing the stent.
  • the above-described light-emitting unit does not always include all of the above-described light groups.
  • Fig. 1 merely shows a preferred example.
  • the above four positions ie, the position of the light group 1 and the light group 2, the position of the light group 3 and the light group 4, the position of the light group 5 and the light group 6, and the light group 7 and the light group 8 are located.
  • the structural or structural combination of any of the positions can be regarded as one light-emitting unit; therefore, in Fig. 1, it can be considered that it includes four light-emitting units. Therefore, in some cases in this embodiment, it is possible that the above-mentioned light emitting unit is not the number shown in FIG. 1.
  • the above one light-emitting unit does not necessarily have to include two light groups, or only one light group, or three light groups.
  • the position of these light-emitting units and the direction in which they are formed are certain. The position is the combination of the above four positions, and the beam pointing must be directed to the visual area, but may point to the difference of the non-visual area. Location only.
  • the non-visual area includes an area unrelated to imaging in the pupil region of the human body and an area around the eye; and as described above, the light-emitting unit itself is to be controlled by the control unit. Under the action, emit light of specified light parameters, including: central wavelength and its spectral composition, light intensity, spectral power density, time modulation frequency of light intensity or/and time modulation duty ratio of light intensity, illuminating position and emission With stop time and so on.
  • the control signal controls the light-emitting unit so that the light emitted by the light-emitting unit can conform to the parameter value; and when there are multiple light-emitting units, the light emitted by each light-emitting unit can be made at the center wavelength and its spectral composition.
  • Time modulation frequency of light intensity The time modulation duty ratio is the same as the light intensity, and is the same as the parameter values defined by the above control signals.
  • these parameters defined by the control signal can be assigned to each of the light-emitting units. The values of these parameters for each lighting unit are lower, but are superimposed to be equal to the parameter values defined by the control signal.
  • the bracket includes a glasses bracket, and the light emitting unit is disposed on an upper edge or a lower edge of an intermediate position in a width direction of the lens frame of the eyeglass bracket. And having a set angle such that the light beam emitted by the light emitting unit is directed to the non-visual area of the pupil corresponding to the position; the nose holder position of the eyeglass holder further includes an adjustment structure for adjusting the eyeglass holder and the pupil The distance between them.
  • the pointing area where each of the light emitting units emits light is determined by the position of the light emitting unit and the structure of the light emitting unit itself.
  • the light emitting unit comprises at least one light group, each light group comprising at least one L ED and an optical structure for focusing the light emitted by the LEDs in the light group to form a parallel light beam (not shown)
  • the mounting position and angle of the optical structure determine the pointing angle of the emitted light beam.
  • the angle of the light group for example, the angle with the horizontal line of the mounting position
  • FIG. 3 is a schematic view showing the installation position of the lamp group on the side of the face.
  • Fig. 4 is a schematic view showing the installation position of the lamp group viewed from the front of the face.
  • typical data of a preferred embodiment includes: The maximum distance of the edge is 4cm; the symmetry distance of the upper and lower edges of the frame to the pupil horizontal plane is 2cm; the vertical distance from the vertical point of the frame to the pupil is 1.5cm; the upper and lower edges of the frame are at an angle of 53 degrees from the pupil straight line to the pupil horizontal plane.
  • 5 is a schematic diagram of a light beam of a lamp group.
  • the LEDs of each lamp group are polarized and focused at a certain angle of divergence, and are symmetrical with respect to a horizontal axis passing through the center of the pupil of the eye, but the axis of each beam is not the same as above.
  • the horizontal axis passing through the center of the pupil of the eye intersects to ensure that the beam emitted by the LED is emitted outside the visual field of the eye.
  • Typical data of a preferred embodiment includes: LED illumination angle of 18 degrees; center spacing of the left and right illumination holes of the upper and lower edges is 7 cm; The distance between the illuminating holes is 1.5cm.
  • the gaunt structure of the lamp group and the mounting structure of the lamp group may include a plurality of types, but regardless of the structure, the purpose is to make the optical performance of the lamp group satisfy the above-mentioned projection of the light into the non-visual zone.
  • the domain does not affect or significantly affect the purpose of the user's vision.
  • the LEDs when a lamp group includes a plurality of LEDs, the LEDs are disposed around a central axis of the optical structure.
  • the lamp group in FIG. 2 includes a red LED having different light wavelengths and a yellow light L ED which are uniformly distributed around the axial position of the reflective structure and driven by different modulated driving signals. And green LEDs.
  • the plurality of lamp groups are respectively driven by different drive signals, and the superposition of the plurality of drive signals is constrained by the control signals output by the control unit.
  • the driving signals are independent, and the driving signals may be different or the same, but the driving signals respectively generate light on the lamp groups, on the sum of their energies. It is constrained by the energy-related parameters of the above optical parameters, and the parameters of frequency, hue and the like are consistent, and are also constrained by the relevant parameters in the above optical parameters.
  • the control unit includes a parameter obtaining module 10, a modulation module 11 and a communication module 12, and the parameter obtaining module 10 selects the optical parameter and forms a modulation signal to be transmitted to the modulation module 11,
  • the modulation module 11 modulates the driving signal of the light emitting unit by using the modulation signal to obtain a modulated optical driving signal and transmits the modulated optical driving signal to the light emitting unit, and drives the light emitting unit to emit light that conforms to the light parameter;
  • the communication module 12 receives a parameter of a setting component of a brain wave of a human body that is currently detected and processed by the external device and uses the illumination device that adjusts the human body rhythm, and transmits the parameter to the parameter acquisition module as the parameter.
  • the module selects the basis of the light parameters.
  • the parameter of the set component in the brain wave includes a frequency value of (3 wave or Y wave), and the parameter obtaining module makes a time modulation frequency of the light intensity in the parameter when the light parameter is selected
  • the received (the frequency of the 3 wave or the Y wave is close or equal.
  • the control unit can start to work (the light has not been illuminated at this time) according to some parameters input by the user. For example, age, etc., select a set of relatively common light parameter values to control the emitted light, and when the light is for a certain period of time, obtain the current (already illuminated) brain waves of the user through other devices.
  • FIG. 6 is a schematic structural view of the illumination device for adjusting the biological rhythm of the human body in the embodiment.
  • the obtained parameter value is transmitted to the parameter obtaining module 10 through the communication module 12, and the parameter obtaining module 10 selects a corresponding parameter value pair according to the value of the received component of the brain wave received.
  • the light for illumination described above is controlled.
  • the parameter acquisition module selects the light parameter
  • the time modulation frequency of the light intensity in the parameter is made close to or equal to the received frequency of the 3 or Y wave.
  • FIG. 6 is a schematic structural view of the illumination device for adjusting the biological rhythm of the human body in the embodiment. In FIG.
  • the communication module 12 receives the parameter value of the specific component of the user's brain wave transmitted by the external device, and transmits it to the parameter obtaining module 10, and the parameter obtaining module 10 according to the parameter value of the specific component of the received brain wave. Selecting some corresponding ones of the optical parameters or the optical parameters that match or correspond to the parameter values, and transmitting them to the modulation module 11, and the modulation module 11 directly or assigns them to the light-emitting unit according to the received parameters.
  • Each of the existing lamp groups (1, 2, ..., 7 and 8 in Fig. 4) forms a modulated drive signal for each lamp group and outputs it to each lamp group.
  • the power source 13 is directly connected to the parameter acquisition unit, and power is supplied to the other units through the unit.
  • the modulated driving signal is a carrier generated by the modulation module 11 to meet a requirement of a waveform parameter in accordance with a relevant parameter (eg, duty ratio) in the optical parameter, and uses other parameters in the optical parameter (eg, modulation frequency). It is modulated.
  • a relevant parameter eg, duty ratio
  • other parameters in the optical parameter eg, modulation frequency
  • the device includes a bracket 16 adapted to be worn on a person's face, and a parameter acquisition module 10, a modulation module 11, and a communication fixed on the bracket 16.
  • the module 12, the power module 13, the LEDs 1 to 8, the power module 13 is electrically connected to the parameter acquisition module 10, the modulation module 11, the communication module 12, and the LED lamp groups 1 to 8;
  • the parameter obtaining module is connected, and the modulation module 11 is connected to the parameter obtaining module 10,
  • the LED lamp groups 1 to 8 are connected to the modulation module 11; the modulation module 11 is configured to control the LED lamp groups 1 to 8 to output specific optical parameters by outputting different driving signals; the parameter obtaining module 10 is configured to call the combination The illumination parameter, the parameter acquisition module 10 transmits the combined illumination parameter to the modulation module 11 for execution.
  • the LED lamp groups 1 to 8 are for outputting light modulated by the modulation module 11; the communication module 12 is for providing a communication interface with the smart device and its APP.
  • the bracket 16 is a glasses bracket, and the outline of the glasses is slightly larger than that of the conventional glasses used in the prior market, which not only supports the use of the adjustment object in the case of not wearing glasses, but also supports the adjustment of the object in the worn glasses. Used below, does not affect the normal use effect.
  • the bracket 16 is designed to meet the usage of different users, expand the scope of use, and improve the utility and effectiveness of the device.
  • the parameter acquisition module 10 includes a core processor and simple input buttons, which are directly connected to the modulation module 11, the communication module 12, and the power module 13, respectively, and are indirectly connected to the LED groups 1 to 8, thereby real-time regulating the entire device.
  • the LED lamp group is fixed to the upper and lower positions of the mirror ring of the bracket 16, and each of the LED lamp groups includes one or two or three LED lamps, and the front end of the illuminator of the LED lamp group reaches the distance of the iris of the human eye. It is 12-16mm. This distance is the light group Adjusted by the position of the bracket 16. As a preferred example, the distance from the front end of the illuminant of the LED lamp group to the iris of the human eye is 14 mm, which can effectively control the stimulation of the retina around the human eye.
  • the plurality of sets of LED light groups can respectively illuminate different regions, so as to adjust the corresponding eye-brain neural network of the region, and function to adjust different biological rhythms.
  • distributed illumination can reduce power density and have the function of reducing the risk of light damage; multiple sets of light groups 1, light groups 2, light groups 3, light groups 4, light groups 5, light groups 6,
  • the lamp group 7 and the lamp group 8 can realize multi-wavelength combination, increase the range of stimulation, and combine multi-color light to reduce the discomfort caused by the monochromatic light to the visual area stimulation.
  • the above-mentioned structural design has the beneficial effects of allowing a certain range of eye movements, such as eye enlargement or rotation, without reducing the adjustment effect or causing discomfort of the adjustment object.
  • the light group 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 can output light waves of different illuminances of different frequencies and different wavelengths, multiple sets of L light groups 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 can achieve different combinations to form a composite light at the pupil.
  • the parameter acquisition unit 10 includes a plurality of modes, and the preset illumination parameters can be selected to achieve a specific adjustment control effect.
  • the light emitted by the LED lamp set 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 after being modulated by the modulation module 11 is irradiated to the eyes, and each of the 4 sets of LED lamp sets 1, 2, 3, 4 or 5, 6, 7, 8 illuminate a single eye.
  • the effective illuminance of the measured corneal surface ranges from 2 to 2000 ux, and the optical power incident from the pupil is in the range of 8-800 uW/cm.
  • each of the LED illuminants on the lamp group 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 is inclined at an angle to the pupil, avoiding the direct macular area, and ensuring effective illumination of different regions of the peripheral retina Includes nasal and lateral areas and does not affect normal vision.
  • Each of the LEDs of the LED lamp set 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 may have high directivity.
  • it can be a pointed epoxy package, or a metal reflective cavity package, or a flat-head package plus a concentrating lens, and without a scattering agent, the illuminating angle is 15 degrees -20 degrees, ensuring that the pupil is not separated when the eyeball is active.
  • the LED light group illuminates the coverage while preventing excessive stray light from illuminating the vicinity of the macula. It can be considered that the diameter of the spot on the surface of the iris is substantially equal to the diameter of the iris.
  • the modulation module 11 controls the specific optical parameters of the LED light group 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 output, and the specific modulation modes mainly include: time frequency, luminous intensity, duty ratio; The modulation effect is expressed as: spectral combination, spectral combination, intensity combination.
  • the modulation module 11 controls the LED light group 1 or 2 or 3 or 4 Specific optical parameters of the output of 5 or 6 or 7 or 8 include frequency modulation, wavelength modulation, intensity modulation, duty cycle modulation, and contrast modulation, color temperature modulation, and power modulation of a plurality of sets of LED lamps.
  • the modulated light is within the acceptable range of the human eye and meets the conventional needs of photobiology research, including blue light with a fixed frequency of 40 Hz.
  • the modulation module 11 and the LED light group 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 are in real time synchronized operation by the control module 10 to modulate the output light stably and quickly.
  • each LED light group can be composed of three LEDs of different wavelengths. For example, red light (central wavelength 650nm), yellow-green light (central wavelength 530nm), blue light (central wavelength 460nm).
  • the modulation module 11 can modulate specific optical parameters of the LED lamp set 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 output, including a single group of LED lamps having a frequency modulation range of 0 Hz-80 Hz, The wavelength modulation range is from 450nm to 670n m, the illumination modulation range is 2-20001ux, and the duty cycle modulation range is 0-100%.
  • the LED lamp set 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 can output light waves of different intensities of different frequencies and different wavelengths.
  • the output operating frequency range is: 0 Hz-80 Hz, which is generally not noticeable to the human eye by more than 24 Hz ;
  • the output wavelength range is from 450 nm to 670 nm, which is represented by, for example, red light (center wavelength 650 nm), yellow-green light (center wavelength 53 Onm). ), blue light wavelength (center wavelength 460nm) three different wavelengths of light; output effective illuminance in the cornea range of 2-20001ux, the size should be guaranteed to be within the acceptable range of the human eye.
  • the communication module 12 (in this embodiment, a Bluetooth communication module) provides a communication interface with the smart device and its APP, and can realize real-time connection communication between the control module 10 and the external smart device, and further expand the function of the device. .
  • the power module 13 is provided with a normal working monitoring function of the human body rhythm adjusting device and a human body biological rhythm adjusting device starting protection function.
  • the power module 13 is regulated by the control module 10 to provide a conventional stable DC power supply for power supply of the entire human biological rhythm adjustment device, and has a normal working monitoring function of the human biological rhythm adjustment device and a device startup protection function.
  • the power module 13 has a function of monitoring the normal operation of the device. If the power module 13 fails to provide a stable current or the voltage is lower than the rated voltage during the operation of the human body rhythm adjustment device, the indicator light on the power module 13 flashes. A power failure warning indicating that the user should be charging.
  • the power module 13 is provided with a human body rhythm adjustment device activation protection function.
  • the power module 13 When the human body biological rhythm adjustment device is activated, the power module 13 causes the control module to be in a buffer setting state by a specific current, thereby controlling the LED lamp sets 1 to 8 require a certain time delay to achieve the maximum intensity required for effective operation, ensuring sufficient time for the human eye.
  • the light emitted by the human body rhythm regulating device is adapted.
  • the modulation module 11 combines the optical modulation technique and the spectral mixing technique, and adopts a tunable modulation mode.
  • the modulation operating frequency range is 0Hz-80Hz, adjustable; the modulation wavelength range is 450nm-670nm, optional; the modulation illumination range is 21ux -20001ux, adjustable.
  • the duty cycle modulation of different LED lamp groups and up to 8 groups of LED lamp groups in different modulation modes high-precision multi-variable and wide-range light modulation can be realized.
  • the non-visual information pathway cells of the brain are stimulated by the modulated light to illuminate the non-visual region, which can effectively affect and regulate the human biological rhythm, adjust the human body related hormone secretion disorders, brain wave disorder, The situation of the biological clock disorder, etc., to improve a series of diseases caused by human biological rhythm disorders.
  • the LED's incident position, illuminating angle, and illuminating intensity are unique. Only a small amount of light affects the macular area of the retina. Most of the light is irradiated on the peripheral retina, and the user can adapt after a short period of use.
  • the overall device bracket design conforms to people's daily eye habits and does not affect people's normal activities.
  • the bracket 16 is in the shape of a spectacles, and the spectacles are slightly larger than the conventional spectacles used in the existing market.
  • the LED light groups 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 may be distributed in corresponding positions, up to a total of eight groups, each group including one to three LEDs, respectively mounted on the eyeglass holder
  • the upper and lower sides of the mirror ring on both sides.
  • the straight line passing through the plane geometric symmetry center of the eyeglass holder and the center of the pupil is the main axis
  • the light group 1 and the light group 2 are located on the upper edge of the longitudinal plane frame passing through the main axis
  • the light group 3 and the light group 4 are located on the main axis.
  • the lower edge of the longitudinal plane frame, the lamp group 5 to the lamp group 8 and the lamp group 1 to the lamp group 4 form a left-right symmetry at a corresponding position.
  • the eyeglass intermediate node 9 is a support point and can be appropriately adjusted according to the difference in the shape of the face and the nose of the adjustment object.
  • the node 9 is provided with a positioning soft rubber, which can be well fitted between the two brow bones, and fixes the distance and angle of the front end of the LED illuminator to the iris of the human eye.
  • the therapeutic effect of blue light of about 40 Hz and about 460 nm on AD disease was verified by an animal experiment.
  • a comparative experiment was conducted with specific illumination as the only variable, in which the experimental group was added with specific illumination for about 1 hour per day, and the control group was not illuminated. After 35 days of experimentation, it was found that the main AD symptoms such as Tau protein after specific light were significantly improved, that is, the condition was improved; compared with the control group (no light group) (100%), the improvement of multiple indicators The percentages are all greater than 50%.
  • This animal experiment results well in support of the present invention.
  • the working mode of the above-mentioned treatment mode is one hour, and the specific implementation process is: opening the switch of the power module 13, the power module 13 is normally started under the device startup protection function, and the simple input on the parameter obtaining module 10 is operated. Press the button to select the AD disease treatment mode.
  • the light modulation module 11 stores the AD disease treatment mode information according to the inside of the device, and up to 8 groups of the LED light groups are simultaneously activated, and the initial frequency is 0 Hz, the wavelength is 650 nm, and the illuminance is 10 lux, which is red light. After 15 minutes, the optical modulation module 11 changes the modulation mode, which is specifically represented by changes in parameters such as time frequency, luminous intensity, and duty ratio.
  • the wavelength is adjusted to 460 nm
  • the illuminance is 81 ux
  • the time modulation frequency is 40 Hz
  • the Y wave of the brain wave is measured for about 20 minutes
  • the maximum frequency component near the 40 Hz ie, the maximum power spectral density corresponding to the frequency
  • the modulation frequency is adjusted to Frequency, then irradiate.
  • the above steps can be repeated, and the optimum frequency point can be found by detecting the frequency, that is, the modulation frequency is closest to the generated chopping frequency.
  • the above optimal frequency irradiation was used until the irradiation time reached 60 minutes.
  • the experiment found that 650nm red light has the effect of repairing retinal damage.
  • blue light 40H Z and irradiation time of 20 - 45 minutes can inhibit the melaclosure of some people with melatonin secretion disorder during the day. It is easy to sleep at night, and it is easy to sleep at night; for example, it is irradiated with 40Hz yellow light for 20-30 minutes, and 40Hz blue light for 30 minutes, which has the effect of improving depression.
  • the invention increases the blue light stimulation effect measurement and the visual damage risk limitation link, and uses the adjustment effect measurement as the signal feedback of the illumination device parameter control to realize dynamic control; the illumination parameter that can obtain the lowest adjustment effect is obtained.
  • the lower limit of the control is implemented, the risk-bearing value is converted into the upper limit of the control of the illuminating parameter, and the precision of the control is improved; and further, the blue irritating effect measurement, the visual damage risk limiting unit and the illuminating device unit are combined to form a complete A feedback-measurement control loop is measured.
  • the specific implementation method is: introducing a brain wave tester based on the existing illumination and control unit of the prior art, using the measured brain wave signal as a real-time representation of the human biological rhythm, and combining the clinical medical experience to evaluate the human body related biological rhythm index.
  • the adjustable range of the combined illumination parameters ensures the controllability of the illumination risk.
  • a menu combination of multiple illuminating parameters that is, a program setting and control of the position of the light source, the wavelength of the light source, and the opening time of the light source are adopted; on the biological rhythm adjusting device, as needed
  • a variety of different human biological rhythm adjustments that is, the use of a plurality of combined illumination parameters combined with its overall integrated effect, to achieve the user's physical condition (symptoms, causes) due to human, time, on-demand adjustment of the human biological rhythm adjustment device
  • the parameters of the large dynamic range are adjusted as much as possible, and the illumination intensity and time modulation of each LED unit are respectively realized by different technical means.
  • the frequency, modulation duty cycle, illuminating time and other parameters are quantitatively adjusted within the dynamic range to maximize the need for different degrees of biological rhythm adjustment.

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  • Health & Medical Sciences (AREA)
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  • Circuit Arrangement For Electric Light Sources In General (AREA)

Abstract

La présente invention concerne un appareil d'éclairage pour réguler les rythmes biologiques humains. L'appareil d'éclairage comprend un bracket porté sur un corps humain, et une unité de commande et une unité d'émission de lumière disposée sur le bracket, l'unité de commande délivrant un signal de commande à l'unité d'émission de lumière pour commander des paramètres de lumière de la lumière émise par l'unité d'émission de lumière; et l'unité d'émission de lumière est disposée sur une position réglée du bracket, forme une lumière, qui est émise par l'unité d'émission de lumière et est générée en fonction du signal de commande délivré par l'unité de commande, dans un faisceau lumineux et la projette sur une zone non visuelle du corps humain portant le bracket. L'implémentation de l'appareil d'éclairage pour réguler les rythmes biologiques humains de la présente invention présente l'effet avantageux suivant : des paramètres d'éclairage peuvent être régulés en fonction d'une rétroaction, de personnes et de maladies, ce qui permet d'obtenir une régulation fine, efficace et sûre des rythmes biologiques humains.
PCT/CN2018/125525 2018-02-09 2018-12-29 Appareil d'éclairage pour réguler les rythmes biologiques humains Ceased WO2019153966A1 (fr)

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