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WO2019153967A1 - Dispositif d'éclairage pour la régulation coopérative de rythmes biologiques humains dans de multiples trajets - Google Patents

Dispositif d'éclairage pour la régulation coopérative de rythmes biologiques humains dans de multiples trajets Download PDF

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Publication number
WO2019153967A1
WO2019153967A1 PCT/CN2018/125528 CN2018125528W WO2019153967A1 WO 2019153967 A1 WO2019153967 A1 WO 2019153967A1 CN 2018125528 W CN2018125528 W CN 2018125528W WO 2019153967 A1 WO2019153967 A1 WO 2019153967A1
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WO
WIPO (PCT)
Prior art keywords
light
parameter
control unit
modulation
unit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2018/125528
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English (en)
Chinese (zh)
Inventor
马君显
马捷
王志建
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyselife Tech Ltd Shenzhen
Original Assignee
Wyselife Tech Ltd Shenzhen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Publication of WO2019153967A1 publication Critical patent/WO2019153967A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0618—Psychological treatment
    • G—PHYSICS
    • G02—OPTICS
    • G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C11/00—Non-optical adjuncts; Attachment thereof
    • G02C11/04—Illuminating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0635—Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0643—Applicators, probes irradiating specific body areas in close proximity
    • A61N2005/0645—Applicators worn by the patient
    • A61N2005/0647—Applicators worn by the patient the applicator adapted to be worn on the head
    • A61N2005/0648—Applicators worn by the patient the applicator adapted to be worn on the head the light being directed to the eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/065—Light sources therefor

Definitions

  • the present invention relates to the field of medical or healthcare equipment, and more particularly to an illumination device that synergistically adjusts the biological rhythm of a human body in multiple ways.
  • Retinal ganglion photoreceptor cells discovered in 2003 is of great significance for revealing the mechanism of adjusting human biological rhythms through light action.
  • the human eye's light signal sensing function includes visual functions associated with retinal cone and rod cells and non-visual functions related to ipRGCs.
  • the former mainly transmits visual light signals to the brain to form visual images, colors and their Changes, while the latter mainly transmits non-visual light signals to the pineal gland of the hypothalamus to participate in the regulation of the circadian clock, thereby producing an adjustment effect on the physiological and mental health of the human body.
  • the prior art there are also special devices or device systems that use light to control diseases or regulate biological rhythms.
  • the technical forms and device forms are different, the principle of blue light stimulating the retina of the human eye to adjust the human body clock is not the same.
  • These devices in the prior art may also have certain effects, but it is undeniable that the defects are also obvious, for example, the sum of the intensity of the emitted light and the invisible illumination of the visual area are only controlled by the illumination intensity and the illumination time.
  • the technical problem to be solved by the present invention is that the adjustment effect of the prior art is not fine, uncontrollable, inefficient, and low in safety, and provides a fine adjustment effect, controllability, better efficiency, and more safety.
  • a good multi-channel illumination device that synergistically regulates the biological rhythm of the human body.
  • the technical solution adopted by the present invention to solve the technical problem is to construct a multi-channel illumination device for cooperatively adjusting the biological rhythm of the human body, including a bracket worn on the human body, a control unit disposed on the bracket, a lighting unit, and audio playback.
  • control unit outputs a control signal to the light emitting unit, and controls a light parameter of the light emitting unit to emit light;
  • the light emitting unit is disposed at a set position of the bracket, and is issued according to the control
  • the light generated by the control signal output by the unit forms a light beam and is projected onto a non-visual area of the human body wearing the bracket;
  • the audio playback unit receives the audio data transmitted by the control unit and plays it; wherein the control The unit selects audio data that is similar to or the same as the rhythm according to the parameter value of the specific component of the current user's brain wave, and sends the audio data to the audio playing unit.
  • control unit includes a parameter acquisition module, a modulation module, and a communication module
  • the parameter acquisition module selects the optical parameter and forms a modulation signal to be transmitted to the modulation module
  • the modulation module uses the modulation signal pair
  • the driving signal of the light emitting unit is modulated to obtain a modulated optical driving signal and transmitted to the light emitting unit, and the light emitting unit is driven to emit light that conforms to the light parameter
  • the parameter obtaining module further selects audio of different music Sending data to the play module
  • the communication module receives a parameter of a set component of a brain wave of a human body currently using the illumination device detected and processed by an external device, and transmits the parameter to the parameter acquisition module as
  • the parameter acquisition module selects the basis of the optical parameter and the audio data.
  • the non-visual area includes an area unrelated to imaging and a region around the eye in the pupil of the human body;
  • the optical parameters include: a central wavelength and a spectral component thereof, a light intensity, a spectral power density, and a temporal modulation of the light intensity. Frequency, time-modulated duty cycle of light intensity, LED illumination position or/and LED emission and stop times.
  • the parameter of the set component in the brain wave includes a frequency value of a brain wave, such as a beta wave or a gamma wave
  • the parameter obtaining module makes the light intensity in the parameter when the light parameter is selected a frequency modulation frequency that is close to or equal to a frequency corresponding to a maximum power spectral density of the received beta wave or gamma wave
  • the parameter acquisition module causing the audio rhythm to be related to the received beta when the audio data is selected
  • the frequency corresponding to the maximum power spectral density of the wave or gamma wave is close or equal.
  • the communication module periodically exchanges data with an external device, and periodically transmits the received data to the parameter acquisition module unit.
  • the light emitting unit includes a plurality of setting positions respectively disposed on the bracket; a pointing area where each of the light emitting units emits light is determined by a position of the light emitting unit and a structure of the light emitting unit itself.
  • the light emitting unit includes at least one light group, each light group including at least one LED and an optical structure that focuses light emitted by the LEDs in the light group to form a parallel light beam; installation position and angle of the optical structure Determines the angle at which the beam is emitted.
  • the lamp set includes a red LED, a yellow LED, and a green LED having different optical wavelengths, which are uniformly distributed around the axial position of the emission structure and driven by different modulated driving signals, respectively.
  • the plurality of lamp groups are respectively driven by different driving signals, and the superposition of the plurality of driving signals is restricted by the control signals output by the control unit.
  • the bracket includes a spectacles holder, and the illuminating unit is disposed on an upper edge or a lower edge of an intermediate position in a width direction of the lens frame of the spectacles holder, and has a set angle so that the illuminating unit emits The light beam is directed to the non-visual area of the pupil corresponding to the position;
  • the audio playback unit is disposed at the end of the leg of the eyeglass holder or the position of the user's ear when worn, the audio playback unit includes a speaker or cooperates with the earphone The output interface used.
  • An illumination device for implementing a multi-channel synergistic adjustment of a human biological rhythm of the present invention has the following beneficial effects: since the control unit is used to control the light emitted by the light-emitting unit, and the control unit is capable of selecting the light parameter,
  • the key parameters of the light intensity, center wavelength, modulation frequency, modulation waveform, duty cycle, etc. can be selected one by one to form a light whose characteristics are composed of a plurality of parameters, thereby making the light Irradiating different non-visual areas of the human eye, different biological rhythm adjustment functions and effects are generated by activating the neural network of the area; achieving fine, controllable, and safe effects of selecting illumination parameters due to adjustment objects, symptoms, and adjustments
  • the existence of the audio playback module not only enables it to select a specific audio rhythm in combination with the set components of the current user's brain waves, stimulates a specific neural network, and enhances the effect of adjusting a specific biological rhythm; more importantly, Through multi-channel synergy with feedback detection,
  • FIG. 1 is a schematic structural view of the apparatus in an embodiment of an illumination device for multi-channel synergistic adjustment of a human biological rhythm
  • Figure 2 is a schematic view showing the position of an LED in a lamp group in the embodiment
  • Figure 3 is a side view showing the position of the lamp group and the pupil in the embodiment
  • Figure 4 is a front elevational view showing the position of the lamp group and the pupil in the embodiment
  • Figure 5 is a schematic view showing the structure of a light beam of the lamp group in the embodiment.
  • Figure 6 is a block diagram showing the functional blocks of the apparatus in the embodiment.
  • the multi-channel illumination device for cooperatively adjusting a human biological rhythm comprises a bracket 16 worn on a human body, and is disposed in the Control unit (including parameter acquisition module 10, modulation module 11 and communication module 12) and illumination unit (ie, lamp group 1, lamp group 2, lamp group 3, lamp group 4, lamp group 5, lamp group 6, lamp) a group 7 and a component of the light group 8 and an audio playback unit 18, the control unit outputs a control signal to the light-emitting unit, and controls a light parameter of the light-emitting unit to emit light; the light-emitting unit is disposed on the bracket 16 At a set position, the light generated by the control signal outputted by the control unit is formed into a bundle of rays and projected onto a non-visual area of the human body wearing the holder; the audio playback unit 18 receives the control The audio data sent by the unit is played and played; wherein the control unit selects audio
  • the above-mentioned light-emitting unit does not always include all of the above-mentioned light groups.
  • FIG. 1 merely shows a preferred example.
  • the above four positions ie, the position of the light group 1 and the light group 2, the position of the light group 3 and the light group 4, the position of the light group 5 and the light group 6, and the light group 7 and the light group 8 are located.
  • the structural or structural combination of any of the positions can be regarded as one light-emitting unit; therefore, in Fig. 1, it can be considered that it includes four light-emitting units. Therefore, in some cases in this embodiment, it is possible that the above-mentioned light emitting unit is not the number shown in FIG. 1.
  • the one light-emitting unit does not necessarily have to include two light groups, or only one light group, or three light groups.
  • the position of the light-emitting units and the direction in which they form the light beam are fixed. The position is the combination of the above four positions, and the beam pointing must be directed to the visual area, but may point to the difference of the non-visual area. Location only.
  • the audio playback unit 18 does not work when the audio data transmitted by the control unit is not received; and when the control unit transmits the audio data to the audio playback unit 18, The audio playback unit 18 starts working to convert the audio data into a sound broadcast.
  • the control unit selects audio data that is similar to or the same as the tempo of the current user's brain wave received by the control unit, and sends the audio data to the audio playback unit 18 according to the parameter value of the specific component of the brain wave of the current user. of.
  • control unit may choose not to output the audio data according to the user setting, or may select Output default audio data.
  • an ambient light sensor 19 is further included, and the ambient light sensor 19 is configured to sense the current illumination intensity of the external environment, so as to appropriately reduce the output light intensity of the control unit in an external environment with strong illumination.
  • the parameter adjusts the light intensity output by the light emitting unit; that is, the light intensity emitted by the light emitting unit can be finely adjusted according to the light intensity of the external environment.
  • the non-visual area includes an area unrelated to imaging and a region around the eye in the range of the pupil of the human body; and as described above, the light-emitting unit itself is to be under the action of a control signal output by the control unit.
  • Light that emits specified light parameters including: center wavelength and its spectral components, light intensity, spectral power density, time modulation frequency of light intensity, time modulation duty cycle of light intensity, position of light-emitting LEDs, or/and LEDs Launch and stop times, etc.
  • the control signal controls the light-emitting unit so that the light emitted by the light-emitting unit can conform to the parameter value; and when there are multiple light-emitting units, the light emitted by each light-emitting unit can be made at the center wavelength and its spectral composition.
  • the time modulation frequency of the light intensity is the same as the time modulation duty ratio of the light intensity, and is the same as the parameter values defined by the above control signal, and in the light intensity and the spectral power density, the parameters defined by the control signal can be allocated. To each of the lighting units, the values of these parameters of each lighting unit are lower, but are superimposed to be equivalent to the parameter values defined by the control signals.
  • the bracket 16 includes a glasses bracket, and the light emitting unit is disposed on an upper edge or a lower edge of an intermediate position in a width direction of the lens frame of the eyeglass holder, and has The angle is set such that the light beam emitted by the light emitting unit is directed to the non-visual area of the pupil corresponding to the position.
  • the above-mentioned playing unit 18 is disposed at the end of the leg of the above-mentioned eyeglass holder or at the position of the eyeglass holder leg when the eyeglass frame is worn on the human body near the user's ear.
  • the audio playback unit 18 includes at least one disposed near the human ear.
  • Micro-speakers for audio signal playback can also include a headphone output connector that enables the use of headphones for sound reproduction.
  • the pointing area where each of the light emitting units emits light is determined by the position of the light emitting unit and the structure of the light emitting unit itself.
  • the light emitting unit includes at least one light group, each light group includes at least one LED and an optical structure (not shown) that focuses the light emitted by the LEDs in the light group to form a parallel light beam;
  • the mounting position and angle determine the angle at which the beam is directed.
  • the above-described mounting position is determined, by adjusting the angle of the light group, for example, the angle with the horizontal line of the mounting position, it is possible to ensure that the light beam emitted by the light group is directed to the non-visual area.
  • FIG. 3 is a schematic view showing the installation position of the lamp group on the side of the face.
  • Fig. 4 is a schematic view showing the installation position of the lamp group viewed from the front of the face.
  • the four light groups corresponding to each eye are symmetrical with respect to the horizontal axis, respectively, with the horizontal line passing through the center of the pupil of the eye as an axis; in Fig.
  • typical data of a preferred embodiment includes: the proximal side of the frame The maximum spacing of the edge is 4cm; the symmetry distance of the upper and lower edges of the frame to the pupil plane is 2cm; the vertical distance from the vertical point of the frame to the pupil is 1.5cm; the upper and lower edges of the frame are at an angle of 53 degrees from the pupil straight line to the pupil horizontal plane.
  • 5 is a schematic diagram of a light beam of a lamp group.
  • the LEDs of each lamp group are polarized and focused at a certain angle of divergence, and are symmetric with respect to a horizontal axis passing through the center of the pupil of the eye, but the axis of each beam is not the same as above.
  • Typical data of a preferred embodiment includes: the LED illumination angle is 18 degrees; the center spacing of the left and right illumination apertures is 7 cm; The distance between the illuminating holes is 1.5 cm.
  • the gaunt structure of the lamp group and the mounting structure of the lamp group may include a plurality of types, but regardless of the structure, the purpose is to make the optical performance of the lamp group meet the above-mentioned light projection to the non-visual area. Affects or does not significantly affect the purpose of the user's vision.
  • the LEDs when a group of lamps includes a plurality of LEDs, the LEDs are disposed about a central axis of the optical structure.
  • the lamp group in FIG. 2 includes red LEDs, yellow LEDs having different light wavelengths, which are uniformly distributed around the axial position of the reflective structure, respectively driven by different modulated driving signals. Green LED.
  • the plurality of light groups are respectively driven by different drive signals, and the superposition of the plurality of drive signals is constrained by the control signals output by the control unit.
  • the drive signals are independent, and the drive signals may be different or the same, but the light generated by the drive signals on the respective sets of lights is on the sum of their energies. It is constrained by the energy-related parameters of the above optical parameters, and the parameters of frequency, hue, etc. are consistent, and are also constrained by relevant parameters in the above optical parameters.
  • the control unit includes a parameter acquisition module 10, a modulation module 11 and a communication module 12, and the parameter acquisition module 10 selects the optical parameter and forms a modulation signal to be transmitted to the modulation module 11, the modulation module 11 Modulating a driving signal of the light emitting unit by using the modulation signal to obtain a modulated optical driving signal and transmitting the modulated light driving signal to the light emitting unit, and driving the light emitting unit to emit light that meets the light parameter; the communication module 12 Receiving a parameter of a set component of a brain wave of a human body currently using the illumination device detected and processed by an external device, and transmitting the parameter to the parameter acquisition module as a basis for the parameter acquisition module to select the light parameter .
  • the parameter of the set component in the brain wave includes a frequency value of the beta wave or the gamma wave
  • the parameter obtaining module makes the time modulation frequency of the light intensity in the parameter and the The frequencies of the received beta or gamma waves are close or equal.
  • the control unit can select a set of pre-set relatively common ones according to certain parameters input by the user, such as age, when starting the work (the lighting has not been performed at this time).
  • the light parameter value controls the emitted light, and after the illumination is performed for a certain period of time, the parameter value of the set component in the current brainwave of the user (which has been illuminated) is obtained by another device, and the obtained parameter value is passed through the above communication.
  • the module 12 transmits the parameter acquisition module 10, and the parameter acquisition module 10 selects the corresponding parameter value to control the light for illumination based on the received value of the set component of the brain wave. For example, according to the frequency value of the ⁇ wave or the ⁇ wave of the current brain wave, the parameter acquisition module makes the time modulation frequency of the light intensity in the parameter and the received ⁇ wave or ⁇ wave when the light parameter is selected. The frequencies are close or equal.
  • the parameter obtaining module 10 While adjusting the light output, the parameter obtaining module 10 has obtained the parameter value of the set component in the brain wave by the communication module 12, and may select the same or similar rhythm according to the parameter value.
  • the music data is transmitted to the above-described playback unit 18 for playback. It is worth mentioning that for a rhythm, there is not only one audio file. That is to say, for one rhythm, a plurality of audio files may be stored, and the above-described parameter obtaining unit 10 can maintain a different audio file for a long time even if the rhythm is constant.
  • Fig. 6 is a view showing the structure of the illumination device in this embodiment.
  • the communication module 12 receives the parameter value of the specific component of the user's brain wave transmitted by the external device, and transmits it to the parameter obtaining module 10, and the parameter obtaining module 10 according to the parameter value of the specific component of the received brain wave. Selecting some corresponding ones of the optical parameters or the optical parameters that match or correspond to the parameter values, and transmitting them to the modulation module 11, and the modulation module 11 directly or assigns them to the light-emitting unit according to the received parameters.
  • the existing individual lamp groups (1, 2, ..., 7 and 8 in Fig. 6) form modulated driving signals for the respective lamp groups and output them to the respective lamp groups.
  • the parameter obtaining module 10 transmits the music data selected according to the received parameter value of the specific component of the brain wave to the playing unit 18 for playing, thereby creating an environment for the user to relax or soothe.
  • the power source 13 is directly connected to the parameter acquisition unit, and power is supplied to the other units through the unit.
  • the modulated driving signal is a carrier generated by the modulation module 11 to meet a requirement of a waveform parameter in accordance with a relevant parameter (eg, duty ratio) in the optical parameter, and uses other parameters in the optical parameter (eg, modulation frequency). It is modulated.
  • the device includes a bracket 16 suitable for being worn on a person's face, and a parameter acquisition module 10, a modulation module 11, and a communication module 12 fixed on the bracket 16.
  • the power module 13 is electrically connected to the parameter obtaining module 10, the modulation module 11, the communication module 12, the LED light groups 1 to 8, the ambient light sensor 19, and the playing module 18; the communication module 12 and the parameter obtaining module 10, the modulation module 11 is connected to the parameter acquisition module 10, and the LED lamp groups 1 to 8 are connected to the modulation module 11; the parameter acquisition module 10 is also connected to the above-mentioned playback module 18.
  • the modulation module 11 is configured to control the LED light groups 1 to 8 to output specific light parameters by outputting different driving signals; the parameter obtaining module 10 is configured to invoke a combined lighting parameter, and the parameter obtaining module 10 combines the combined lighting parameters. It is transmitted to the modulation module 11 for execution.
  • the LED lamp groups 1 to 8 are for outputting light modulated by the modulation module 11;
  • the communication module 12 is for providing a communication interface with an external smart device and its APP.
  • the playout mode of the play module 18 can also be various, for example, ear play and environment play audio, etc., and the play module 18 can also be turned on and off by receiving the signal of the communication module 12.
  • the bracket 16 is a glasses bracket, and the outline of the glasses is slightly larger than that of the conventional glasses used in the prior market, which not only supports the use of the adjustment object in the case of not wearing the glasses, but also supports the adjustment object to be used in the case of wearing glasses. Does not affect the normal use effect.
  • the bracket 16 is designed to meet the usage of different users, expand the scope of use, and improve the utility and effectiveness of the device.
  • the parameter acquisition module 10 includes a core processor and simple input buttons, which are directly connected to the modulation module 11, the communication module 12, and the power module 13, respectively, and are indirectly connected to the LED lamp groups 1 to 8, thereby real-time regulating the entire device.
  • the LED lamp group is fixed to the upper and lower positions of the mirror ring of the bracket 16, and each of the LED lamp groups includes one or two or three LED lamps, and the front end of the illuminator of the LED lamp group reaches the distance of the iris of the human eye. It is 12-16mm. This distance is adjusted by the position of the lamp set through the bracket 16. As a preferred example, the distance from the front end of the illuminant of the LED lamp group to the iris of the human eye is 14 mm, which can effectively control the stimulation of the retina around the human eye.
  • Multiple groups of LED light groups can be respectively photographed in different regions in order to adjust the corresponding eye-brain neural network of the region, and function to adjust different biological rhythms.
  • distributed illumination can reduce power density and have the function of reducing the risk of illumination damage; multiple groups of lamps 1, lamp group 2, lamp group 3, lamp group 4, lamp group 5, lamp group 6,
  • the lamp group 7 and the lamp group 8 can realize multi-wavelength combination, increase the range of stimulation, and combine multi-color light to reduce the discomfort caused by the monochromatic light to the visual area stimulation.
  • the above-mentioned structural design has the beneficial effects of allowing a certain range of eye movements, such as eye enlargement or rotation, without reducing the adjustment effect or causing discomfort of the adjustment object.
  • the light group 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 can output light waves of different illuminances of different frequencies and different wavelengths, multiple sets of L light groups 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 can achieve different combinations to form a composite light at the pupil.
  • the parameter acquisition unit 10 includes a plurality of modes, and may select a combined illumination parameter set in advance to achieve a specific adjustment control effect.
  • the LED lamp group 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 after being modulated by the modulation module 11 is irradiated to the eyes, and every 4 groups of LED lamp groups 1, 2, 3, 4 or 5 6,6,8 illuminate a single eye.
  • the effective illuminance of the measured corneal surface ranges from 2 to 2000 lux, and the optical power incident from the pupil is in the range of 8-800 uW/cm.
  • each LED illuminant on the lamp group 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 is inclined at an angle to the pupil to avoid directing the macular area, while ensuring effective illumination of different regions of the peripheral retina including the nasal region And side areas do not affect normal vision.
  • Each of the LEDs 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 may have high directivity.
  • it can be a pointed epoxy package, or a metal reflective cavity package, or a flat-head package plus a concentrating lens, and without a scattering agent, the illuminating angle is 15 degrees -20 degrees, ensuring that the pupil is not separated when the eyeball is active.
  • the LED light group illuminates the coverage while preventing excessive stray light from illuminating the vicinity of the macula. It can be considered that the diameter of the spot on the surface of the iris is substantially equal to the diameter of the iris.
  • the modulation module 11 controls specific optical parameters of the LED lamp set 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 output, and the specific modulation modes mainly include: time frequency, luminous intensity, duty ratio; final modulation effect performance It is: spectral combination, spectrum combination, intensity combination.
  • the modulation module 11 controls specific optical parameters of the LED lamp set 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 output, including frequency modulation, wavelength modulation, intensity modulation, and duty of a single group of LED lamps Contrast modulation, color temperature modulation, and power modulation of multiple sets of LED lamps than modulation and integration.
  • the modulated light is within the acceptable range of the human eye and meets the conventional needs of photobiology research, including blue light with a fixed frequency of 40 Hz.
  • the modulation module 11 and the LED lamp set 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 are commanded in real time by the control module 10 to synchronously and quickly modulate the output light.
  • each LED light group can be composed of three LEDs of different wavelengths. For example, red light (center wavelength 650 nm), yellow-green light (center wavelength 530 nm), and blue light (center wavelength 460 nm).
  • the modulation module 11 can modulate the specific optical parameters of the LED lamp set 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 output, including the frequency modulation range of the single group LED lamp is 0 Hz-80 Hz, the wavelength modulation range The range of illumination is from 450nm to 670nm, the illumination modulation range is 2-2000lux, and the duty cycle modulation range is 0-100%.
  • the LED lamp set 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 can output light waves of different intensities of different frequencies and different wavelengths.
  • the output operating frequency range is: 0 Hz-80 Hz, which is generally not noticeable to the human eye by more than 24 Hz ;
  • the output wavelength range is from 450 nm to 670 nm, which is represented by, for example, red light (center wavelength 650 nm) and yellow-green light (center wavelength 530 nm).
  • blue wavelength (center wavelength 460nm) three different wavelengths of light; output effective illuminance in the cornea range of 2-2000lux, the size should be guaranteed to be within the acceptable range of the human eye.
  • the communication module 12 (in this embodiment, a Bluetooth communication module) provides a communication interface with the smart device and its APP, and can realize real-time connection communication between the control module 10 and the external smart device, thereby further expanding the function of the device.
  • the power module 13 is provided with a normal working monitoring function of the human biological rhythm adjusting device and a start protection function of the human biological rhythm adjusting device.
  • the power module 13 is regulated by the control module 10 to provide a conventional stable DC power supply for power supply of the entire human biological rhythm adjustment device, and has a normal working monitoring function of the human biological rhythm adjustment device and a device startup protection function.
  • the power module 13 has a normal working monitoring function of the device. If the power module 13 fails to provide a stable current or the voltage is lower than the rated voltage during the operation of the human biological rhythm adjusting device, the prompting light on the power module 13 will flash. A power failure warning indicating that the user should be charging.
  • the power module 13 is provided with a human body rhythm adjustment device activation protection function.
  • the power module 13 When the human body biological rhythm adjustment device is activated, the power module 13 causes the control module to be in a buffer setting state by a specific current, thereby controlling the The LED lamp groups 1 to 8 require a certain time delay to achieve the maximum intensity required for effective operation, ensuring that the human eye has sufficient time to adapt to the light emitted by the human biological rhythm adjustment device.
  • the modulation module 11 combines an optical modulation technique with a spectral mixing technique, employing a tunable modulation mode.
  • Modulation operating frequency range is 0Hz-80Hz, adjustable; modulation wavelength range is 450nm-670nm, optional; modulation illumination range is 2lux -2000lux, adjustable.
  • modulation illumination range is 2lux -2000lux, adjustable.
  • the non-visual information pathway cells of the brain can be stimulated, and the human biological rhythm can be effectively affected and adjusted, and the human body related hormone secretion disorder, brain wave disorder, biological clock disorder, etc. can be adjusted.
  • the situation improves a series of conditions caused by human biological rhythm disorders.
  • the LED's incident position, illuminating angle, and illuminating intensity are unique. Only a small amount of light affects the macular area of the retina. Most of the light is irradiated on the peripheral retina, and the user can adapt after a short time of use.
  • the overall device bracket design conforms to people's daily eye habits and does not affect people's normal activities.
  • the bracket 16 is in the shape of a spectacles, and the spectacles are slightly larger than the conventional spectacles used in the existing market.
  • the LED light groups 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 may be distributed in corresponding positions, up to a total of eight groups, each group including one to three LEDs, respectively mounted on the eyeglass holder
  • the upper and lower sides of the mirror ring on both sides.
  • the straight line passing through the plane geometric symmetry center of the eyeglass holder and the center of the pupil is the main axis
  • the light group 1 and the light group 2 are located on the upper edge of the longitudinal plane frame passing through the main axis
  • the light group 3 and the light group 4 are located on the main axis.
  • the lower edge of the longitudinal plane frame, the lamp group 5 to the lamp group 8 and the lamp group 1 to the lamp group 4 are symmetrically located at corresponding positions.
  • the eyeglass intermediate node 9 is a support point and can be appropriately adjusted according to the difference in the shape of the face and the nose of the adjustment object.
  • the node 9 is provided with a positioning soft rubber, which can be well fitted between the two brow bones, and fixes the distance and angle of the front end of the LED illuminator to the iris of the human eye.
  • the therapeutic effect of blue light of about 40 Hz and about 460 nm on AD disease was verified by animal experiments.
  • a comparative experiment was conducted with specific illumination as the only variable, in which the experimental group was added with specific illumination for about 1 hour per day, and the control group was not illuminated. After 35 days of experimentation, it was found that the main AD symptoms such as Tau protein after specific light were significantly improved, that is, the condition was improved; compared with the control group (no light group) (100%), the improvement of multiple indicators The division is greater than 50%.
  • clinical validation of AD patients was carried out. Taking the widely used MMSE and MOCA scales as examples, the scores of AD patients were significantly improved.
  • the working mode of the above-mentioned treatment mode is one hour.
  • the specific implementation process is: opening the switch of the power module 13, the power module 13 is normally started under the device startup protection function, and the simple input on the parameter acquisition module 10 is operated. Press the button to select the AD disease treatment mode.
  • the light modulation module 11 stores the AD disease treatment mode information according to the inside of the device, and up to 8 groups of the LED light groups are simultaneously activated, and the initial frequency is 0 Hz, the wavelength is 650 nm, and the illumination is 10 lux, which is red light. After 15 minutes, the light modulation module 11 changes the modulation mode, which is specifically represented by changes in parameters such as time frequency, luminous intensity, and duty ratio.
  • the wavelength is adjusted to 460 nm
  • the illuminance is 8 lux
  • the time modulation frequency is 40 Hz
  • the gamma wave of the brain wave is measured for about 20 minutes
  • the maximum frequency component near the 40 Hz ie, the maximum power spectral density corresponding to the frequency
  • the modulation frequency is adjusted to Frequency, then irradiate.
  • the above steps can be repeated, during which the frequency can be found to find the optimum frequency point, that is, the modulation frequency is closest to the generated gamma wave frequency.
  • the above optimal frequency irradiation was used until the irradiation time reached 60 minutes.
  • the invention increases the blue light stimulation effect measurement and the visual damage risk limitation link, and uses the adjustment effect measurement as the signal feedback of the illumination device parameter control to realize dynamic control; and the illumination parameter that can obtain the lowest adjustment effect is implemented as a parameter.
  • the lower limit of control the value that can bear the risk is converted into the upper limit of the control of the illuminating parameter, and the precision of the control is improved; and further, the measurement of the blue irritating effect, the visual damage risk limiting unit and the illuminating device unit together form a complete measurement-feedback - Judging the control loop.
  • the specific implementation method is that, based on the existing illumination and control unit of the prior art, a brain wave tester is introduced, and the measured brain wave signal is used as a real-time representation of the human biological rhythm, and the human body related biological rhythm index is evaluated in combination with clinical medical experience.
  • the adjustable range of combined illumination parameters ensures controllability of the illumination risk.
  • a menu combination of multiple illuminating parameters that is, a program setting and control of the position of the light source, the wavelength of the light source, and the opening time of the light source are adopted; on the human biological rhythm adjusting device, various kinds are realized as needed
  • the regulation of the human biological rhythm that is, the use of a plurality of combined illumination parameter combinations of its overall integrated effect, to achieve the user's physical condition (symptoms, causes) due to human, due to the time, adjust the function of the human biological rhythm adjustment device.
  • the parameters of the large dynamic range can be adjusted as much as possible, and the illuminating intensity, time modulation frequency and modulation of each LED unit are respectively realized by different technical means.
  • the parameters such as duty cycle and illuminating time are quantitatively adjusted within the dynamic range to maximize the satisfaction of different degrees of biological rhythm adjustment.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Developmental Disabilities (AREA)
  • Hospice & Palliative Care (AREA)
  • Social Psychology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • General Physics & Mathematics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Optics & Photonics (AREA)
  • Circuit Arrangement For Electric Light Sources In General (AREA)

Abstract

L'invention concerne un dispositif d'éclairage pour la régulation coopérative de rythmes biologiques humains dans de multiples trajets, comprenant un support (16), une unité de commande disposée sur le support (16), des unités électroluminescentes et des unités de lecture audio (18), l'unité de commande délivrant des signaux de commande aux unités électroluminescentes et commandant des paramètres optiques d'une lumière émise par les unités électroluminescentes ; les unités électroluminescentes étant placées dans des positions définies du support (16), permettant à la lumière émise de celles-ci, qui est générée en fonction des signaux de commande délivrés par l'unité de commande, de former des faisceaux lumineux, et projetant les faisceaux lumineux vers une zone non-visuelle du corps humain portant le support (16) ; les unités de lecture audio (18) recevant et lisant des données audio envoyées par l'unité de commande ; et l'unité de commande déterminant les données audio avec des rythmes similaires ou identiques à des valeurs de paramètre de composantes spécifiques d'ondes cérébrales de l'utilisateur actuel et envoyant les données audio aux unités de lecture (18). La présente invention présente les effets bénéfiques suivants : de multiples voies neurales, telles que l'éclairage et l'audio, peuvent être utilisées pour agir de manière coopérative sur le système nerveux d'un corps humain, et une fonction de régulation de rythme biologique plus précise, plus efficace et plus sûre peut être réalisée.
PCT/CN2018/125528 2018-02-09 2018-12-29 Dispositif d'éclairage pour la régulation coopérative de rythmes biologiques humains dans de multiples trajets Ceased WO2019153967A1 (fr)

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CN108245783A (zh) * 2018-02-09 2018-07-06 深圳市慧智生命科技有限公司 一种调节人体生物节律的光照装置
CN108211131A (zh) * 2018-02-09 2018-06-29 深圳市慧智生命科技有限公司 一种多途径协同调节人体生物节律的光照装置
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CN114558248A (zh) * 2022-03-01 2022-05-31 三维医疗科技有限公司 调节哺光仪红光照射的系统及方法
CN117138245B (zh) * 2023-09-26 2024-08-09 深圳市翰腾企业管理咨询有限公司 拼接光照护理装置的控制方法以及存储介质
CN119333791B (zh) * 2024-12-18 2025-11-04 星空深智(杭州)科技有限公司 一种搭载散射光源的补光仪

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