WO2019149425A1 - Cleaning preparation containing polyquaternium-6 polymers - Google Patents

Abstract

The present invention relates to a cosmetic cleaning composition containing polyquaternium-6 polymers, anionic surfactants and amphoteric and/or zwitterionic surfactants. The cleaning composition allows for the effective deposition of antimicrobial polyquaternium-6 polymers on skin.

Description

 Beiersdorf Aktiengesellschaft

 Hamburg

Pure preparation containing polyquaternium-6 polymers

The present invention relates to a cosmetic cleansing preparation comprising polyquaternium-6 polymers, anionic surfactants and amphoteric and / or zwitterionic surfactants. The cleaning preparation allows effective deposition of anti-microbial polyquaternium-6 polymers on the skin.

Cosmetic products are generally not only beautiful and attractive

but with their effect, they contribute significantly to an increased self-esteem and to the well-being of the people. Demensprechend the most diverse cosmetic products for daily cleaning and care of the skin are used.

A key parameter is the removal and / or suppression of the growth of bacteria that adversely affect the appearance of the skin or cause unpleasant odors by breaking down odorless sweat. A well-known bacterium is Staphylococcus aureus (S. aureus), which promotes the formation of purulent blisters and pustules, especially on dry, chapped skin, as occurs in atopic dermatitis. In addition, S. aureus also produces bacterial

Superantigens that maintain and exacerbate atopic dermatitis.

 The Corynebacterium jeikeium is one of the main causes of the typical

Sweat smell that occurs due to the release of fatty acid residues.

By cleaning the skin with cosmetic cleansing preparations can

Sweat residues, dirt and dead skin remains to be removed. Demensprechend the sweat-degrading bacteria is temporarily deprived of a food base. The time until the well-known foul smell occurs again is delayed.

If the smell of sweat over a longer period, for example under the armpits, be avoided, it is necessary to apply deodorants to the skin. Deodorants are products which contain special anti-microbial agents which reduce the growth of bacteria such as Corynebacterium jeikeium or Staphylococcus epidermidis. Deodorants are therefore usually applied after cleaning the skin and remain there to develop their antibacterial effect in the long term. WO 2013052454 A1 lists an overview of known polyquaternium polymers and their trade names.

WO 2016012420 A2 discloses that complex quaternary ammonium polymer compounds, which are known under the INCI nomenclature designation Polyquaternium-6, have a surprisingly strong deodorant or anti-microbial action against Corynebacterium jeikeium or Staphylococcus epidermidis. In addition, it works

Polyquaternium-6 is also anti-microbial against the growth of the bacterium Staphylococcus aureus. However, Polyquaternium-6 is not anti-adhesive and thus does not prevent the adhesion of bacteria to surfaces.

Polyquaternium-6 (PQ-6) is a polymeric quaternary ammonium salt formed from the homopolymerization of the diallyldimethylammonium chloride (DADMAC) monomer.

For example, polyquaternium-6 may be commercially available under the trade designation Flocare C106 from FA. SNF SAS (SNF COSMETICS).

It is desirable to provide cosmetic cleansing preparations which allow the washing process to effectively deposit anti-microbial agents such as Polyquaternium-6 on the skin. In particular, the anti-microbial agents should after the

Washing the skin for an extended period of time will reduce bacterial growth.

The problem, however, is that cosmetic cleansing preparations often only briefly in contact with the skin when used in the shower. These are applied to the wet skin, diluted with the remaining water on the skin and then removed directly with water again. Accordingly, it is difficult in the short contact time to transfer an effectively effective amount of the anti-microbial drugs to the skin, which remains even after rinsing on the skin. Therefore, a longer-lasting anti-microbial effect can not be guaranteed and the consumer's freshness after the cleansing sensation soon subsides.

Another problem is that the cosmetic cleaning preparations contain mostly anionic surfactants. In combination with cationic active ingredients, it is therefore possible, in particular with anionic surfactants, for complex formation and deactivation of the active ingredients. Furthermore, the interaction of the cationic active ingredients with anionic surfactants often leads to unstable or cloudy cosmetic preparations. The object of the present invention was to eliminate the disadvantages of the prior art and to provide in particular cosmetic cleansing preparations which allow an increased deposition of an antimicrobial active ingredient on the skin. Further, it is desirable if such cosmetic cleansing formulations have good foaming power and low haze effects.

Surprisingly, it has now been found that cosmetic cleansing preparations can be provided by the present invention which meet the requirements and do not have the described problems and disadvantages.

The invention relates to a cosmetic cleaning preparation containing

 a) one or more anionic surfactants,

 b) one or more amphoteric and / or zwitterionic surfactants, and

 c) polyquaternium-6;

characterized in that the weight ratio of the anionic surfactants to the amphoteric and / or zwitterionic surfactants 1: 1 to 1: 10, preferably 1: 1, 1 to 1: 8, more preferably 1: 1, 15 to 1: 5 and particularly preferred 1: 1, 15 to 1: 2.

Surprisingly, it has been found that the inventive cosmetic

Cleaning preparation it allows that after flushing with water on the skin a significant reduction in bacteria is achieved. Accordingly, the cleaning preparation according to the invention allows a surprisingly increased deposition of polyquaternium-6 polymers.

Also object of the present invention is thus the use of

cosmetic cleaning preparation according to the invention for the reduction of

Corynebacterium jeikeium, Staphylococcus epidermidis and / or Staphylococcus aureus on the skin.

Another object of the present invention is a method for the deposition of Polyquaternium-6 on the skin, characterized in that the cleaning preparation according to the invention is applied to wet skin and rinsed again within a period of 5 seconds to 5 minutes from the skin with water.

If the term skin is used, it preferably refers to the human skin. All weight percentages (% by weight) listed below are based on the total weight of the cosmetic, unless stated otherwise

Cleaning preparation.

If in the following description ratios of certain

 Components / substances / substance groups are disclosed, these ratios, unless otherwise stated, relate to weight ratios of

Components / substances / groups.

The formulations "according to the invention", "advantageous according to the invention", "advantageous in the sense of the present invention" etc., in the context of the present disclosure always relate both to the preparation according to the invention and to the invention

Use and the method according to the invention.

The term "free from" in the context of the present disclosure means that the proportion of the respective substance is less than 0.05% by weight. This will ensure that

Introductions or contamination with these substances should not be included as being "free of" according to the invention.

The term "cationic charge density" as used in this disclosure refers to the ratio of the number of positive charges on a monomer unit making up the polymer to the molecular weight of the monomer unit. The

Charge density is reported in meq / g (milli-equivalents per gram). The charge density is always given for a pH of 7.

Unless otherwise stated, all experiments are carried out under normal conditions

carried out. The term "normal conditions" means 20 ° C, 1013 hPa and a relative humidity of 50%.

Anionic surfactants generally have carboxylate, sulfate or sulfonate groups as functional groups. In aqueous solution, they form negatively charged organic ions in an acidic or neutral medium.

Anionic surfactants to be used advantageously according to the invention are sulfuric acid esters, such as Alkyl ether sulfate, for example sodium, ammonium, magnesium, MIPA, TIPA lauryl ether sulfate, sodium myristyl ether sulfate and the substance Sodium C12-13-Parethsulfate known under the INCI name;

 Alkyl sulfates, for example, sodium, ammonium and TEA lauryl sulfate;

and sulfonic acids and salts, such as

 Acyl isethionates, e.g. Sodium / ammonium cocoyl isethionate;

 alkylarylsulfonates;

 Alkyl sulfonates, for example sodium coconut monoglyceride sulfate, sodium C 12-14 olefin sulfonate, sodium lauryl sulfoacetate and magnesium PEG-3 cocamide sulfate, sulfosuccinates, for example dioctyl sodium sulfosuccinate, disodium laurethsulfosuccinate, disodium lauryl sulfosuccinate, disodium undecylenamido MEA sulfosuccinate and PEG-5 lauryl citrate sulfosuccinate;

Further advantageously used anionic surfactants are acylamino acids and their salts, such as

 Acylglutamates, for example, sodium acylglutamate, di-TEA-palmitoylaspartate and sodium caprylic / capric glutamate;

 Acyl peptides, for example, palmitoyl-hydrolyzed milk protein, sodium cocoyl-hydrolyzed soy protein, and sodium / potassium cocoyl-hydrolyzed collagen, sarcosinates, for example, myristoyl sarcosine, TEA-lauroyl sarcosinate, sodium lauroyl sarcosinate, and sodium cocoyl sarcosinate;

 Taurates, for example, sodium lauroyl taurate and sodium methyl cocoyl taurate;

 Acyl lactylate, lauroyl lactylate, caproyl lactylate;

 alaninates;

Further anionic surfactants to be used advantageously are the groups of the carboxylic acids and carboxylic acid derivatives specified below:

 Carboxylic acids, for example, lauric acid, aluminum stearate, magnesium alkoxide and zinc undecylenate;

 Ester carboxylic acids, for example, calcium stearoyl lactylate, laureth-6-citrate, and sodium PEG-4 lauramide carboxylate;

Ether carboxylic acids, for example sodium laureth-13-carboxylate and sodium PEG-6-cocamide carboxylate; and phosphoric acid esters and salts such as DEA-oleth-10-phosphate and dilaureth-4-phosphate. It is particularly advantageous if the cosmetic cleaning preparation according to the invention comprises one or more anionic surfactants according to the formula (I)

R0 _(CH2 CH20) x- (CH2-CHR ¹ 0) y (CH2CH20) z-S0 ₃ - M ⁺ contains (I), characterized in that

 R is a linear or branched Ce-C-alkyl radical or mixtures of different linear or branched Cs-Cis-alkyl radicals;

R ^{1 is} methyl, ethyl or mixtures thereof;

M ⁺ is a cation selected from the group consisting of alkali metals, NH ₄ ⁺ and HNR ^{+ 2} is _3, wherein R ² is selected from the group consisting of linear or branched alkyl groups, CH ₂ CH ₂ OH and CH ₂ CH (OH) CH ₃ ;

x is an integer number in the range of 0-3;

y is an integer number in the range 0-10; and

z is an integer number in the range 0 - 30.

Particularly preferred surfactants of the formula (I) are selected from the group sodium laureth sulfate (sodium lauryl ether sulfate) and / or ammonium laureth sulfate

(Ammonium lauryl ether sulfate).

Advantageously, the proportion of anionic surfactants, in particular those previously listed as particularly advantageous anionic surfactants which are sodium laureth sulfates and / or ammonium laureth sulfates, in the inventive cosmetic cleaning preparation 0, 1 wt .-% to 12 wt .-%, preferably 2 wt .-% to 10 wt .-% and particularly preferably 3 wt .-% to 8 wt .-%, based on the total weight of the cleaning preparation.

Furthermore, the cosmetic cleaning preparation according to the invention contains one or more amphoteric and / or zwitterionic surfactants. Advantageously used amphoteric and / or zwitterionic surfactants

 Acyl / dialkylethylenediamine, for example sodium acylamphoacetate,

 Disodium acylamphodipropionate, disodium alkyl amphodiacetate, disodium

 Cocoamphodiacetate, sodium cocoamphomonoacetate,

 Sodium acylamphohydroxypropylsulfonate, disodium acylamphodiacetate and

 sodium acyl;

 N-alkylamino acids, for example aminopropylalkylglutamide,

 Alkylaminopropionic acid, sodium alkylimidodipropionate and

 lauroamphocarboxyglycinate;

Betaines, for example Coco Betaine, Cocoamidopropyl Betaine; and Sultaines, for example Lauryl Hydroxy Sultaine.

Particularly advantageous are the amphoteric and / or zwitterionic surfactants known under the INCI names Sodium Cocoamphoacetate, Disodium

Cocoamphodiacetate, sodium cocoamphopropionate, disodium cocoamphodipropionate, coco betaine, lauryl betaine and / or cocamidopropyl betaine. From the above group, cocamidopropyl betaine is selected as the most preferred amphoteric and / or zwitterionic surfactant.

Advantageously, the proportion of amphoteric and / or zwitterionic surfactants, in particular those previously listed as particularly advantageous amphoteric and / or zwitterionic surfactants, in the cosmetic cleaning preparation according to the invention 3 wt .-% to 20 wt .-%, preferably 4 wt .-% to 17 wt .-% and particularly preferably 5.5 wt .-% to 13 wt .-%, based on the total weight of the cleaning preparation.

Advantageous embodiments of the invention are therefore characterized in that cocamidopropylbetaine in the cosmetic cleaning preparation according to the invention in a proportion of 3 wt .-% to 20 wt .-%, preferably 4 wt .-% to 17 wt .-% and particularly preferably 5.5 Wt .-% to 13 wt .-%, based on the total weight of the cleaning preparation is included. Within these embodiments, it is furthermore particularly preferred if, in addition to cocamidopropylbetaine, no further amphoteric and / or zwitterionic surfactants are present.

To after the rinsing of the cosmetic cleaning preparation according to the invention of the skin with water effective antimicrobial activity on the skin against

It is essential that the ratio by weight of the anionic surfactants to the amphoteric and / or zwitterionic surfactants is from 1: 1 to 1:10, preferably from 1: 1, 1 to 1: 8, Corynebacterium jeikeium, Staphylococcus epidermidis and / or staphylococcus aureus. more preferably 1: 1, 15 to 1: 5 and especially preferably 1: 1, 15 to 1: 2. Within the above-defined weight ratios of the anionic surfactants to the amphoteric and / or zwitterionic surfactants finds a particularly effective deposition of

Polyquaternium-6 on the skin instead. In addition, the cleaning preparation with Polyquaternium-6 when using the surfactants in the defined weight ratios to a significantly lower turbidity.

Furthermore, it is advantageous if the polyquaternium-6 polymers at a pH of 7 have a charge density greater than or equal to 5 meq / g, preferably greater than 6 meq / g. Furthermore, it is also advantageous if the polyquaternium-6 polymers have an average molecular weight (molecular weight) of 50,000 g / mol to 800,000 g / mol, preferably 100,000 g / mol to 500,000 g / mol and particularly preferably 120,000 g / mol to 200,000 g / have mol.

Advantageously, the proportion by weight of the polyquaternium-6 polymers in the cosmetic cleaning preparation is from 0.2% by weight to 3% by weight, preferably from 0.5% by weight to 2.5% by weight and particularly preferably 0.75% by weight. -% to 2 wt .-%, based on the total weight of the cosmetic cleaning preparation.

In a first preferred embodiment of the invention, the cosmetic cleansing preparation according to the invention contains

 a) one or more anionic surfactants, preferably selected from the group of

 anionic surfactants according to the formula (I):

R0 (CH2CH20) x- (CH2-CHR ¹ 0) y (CH 2 CH ₂ 0) z-S03- M ⁺ (I) characterized in that

 R is a linear or branched Ce-C «-alkyl radical or mixtures of different linear or branched Cs-C-he-alkyl radicals;

R ^{1 is} methyl, ethyl or mixtures thereof;

M ⁺ is a cation selected from the group consisting of alkali metals, NH ₄ ^+, and HNR ² 3 ^+, wherein R ² is selected from the group consisting of linear or branched alkyl, CH2CH2OH, and CH ₂ CH (OH) CH _3;

 x is an integer number in the range of 0-3;

 y is an integer number in the range 0-10; and

 z is an integer number in the range 0-30;

 b) one or more amphoteric and / or zwitterionic surfactants, preferably selected from the group Sodium Cocoamphoacetate, Disodium Cocoamphodiacetate, Sodium Cocoamphopropionate, Disodium Cocoamphodipropionate, Coco Betaine, Lauryl Betaine and / or Cocamidopropylbetaine; and

 c) polyquaternium-6;

characterized in that the weight ratio of the anionic surfactants a) to the amphoteric and / or zwitterionic surfactants b) 1: 1 to 1:10, preferably 1: 1, 1 to 1: 8, more preferably 1: 1, 15 to 1: 5 and more preferably 1: 1, 15 to 1: 2.

Within this first embodiment, it is particularly preferred if the

Cosmetic cleaning preparation according to the invention, in each case based on the

Total weight of the cleaning preparation, a) one or more anionic surfactants according to the general formula (I):

R0 _(CH2 CH20) x- (CH2-CHR ¹ 0) y (CH2CH20) z-S0 ₃ - M ⁺ (I) characterized in that

 R is a linear or branched Ce-C-is-alkyl radical or mixtures of different linear or branched Cs-Cis-alkyl radicals;

R ^{1 is} methyl, ethyl or mixtures thereof;

M ⁺ is a cation selected from the group consisting of alkali metals, NH ₄ ^+, and HNR ² 3 ^+, wherein R ² is selected from the group consisting of linear or branched alkyl, CH2CH2OH, and CH ₂ CH (OH) CH _3;

 x is an integer number in the range of 0-3;

 y is an integer number in the range 0-10; and

 z is an integer number in the range 0-30;

 b) 3 wt .-% to 20 wt .-%, preferably 4 wt .-% to 17 wt .-% and particularly preferably 5.5 wt .-% to 13 wt .-% of one or more amphoteric and / or zwitterionic Surfactants selected from the group Sodium Cocoamphoacetate, Disodium Cocoamphodiacetate, Sodium Cocoamphopropionate, Disodium

 Cocoamphodipropionates, coco betaines, lauryl betaines and / or

 cocamidopropyl; and

 c) 0.2 wt .-% to 3 wt .-%, preferably 0.5 wt .-% to 2.5 wt .-% and particularly preferably 0.75 wt .-% to 2 wt .-% Polyquaternium-6 ;

characterized in that the weight ratio of the anionic surfactants a) to the amphoteric and / or zwitterionic surfactants b) 1: 1 to 1:10, preferably 1: 1, 1 to 1: 8, more preferably 1: 1, 15 to 1: 5 and more preferably 1: 1, 15 to 1: 2.

Particularly preferred cosmetic cleaning preparations according to the invention within the first embodiment contain, in each case based on the total weight of the cleaning preparation,

 a) Sodium Laureth Sulfate and / or Ammonium Laureth Sulfate;

 b) 4% by weight to 17% by weight, preferably 5.5% by weight to 13% by weight, of one or more amphoteric and / or zwitterionic surfactants selected from the group consisting of sodium cocoamphoacetate, disodium cocoamphodiacetate, sodium cocoamphopropionate , Disodium cocoamphodipropionate, coco betaine, lauryl betaine and / or

 cocamidopropyl; and

 c) from 0.5% to 2.5% by weight, preferably from 0.75% to 2% by weight of polyquaternium-6; characterized in that no further anionic surfactants and no further amphoteric and / or zwitterionic surfactants are contained and that the

Weight ratio of sodium laureth sulfate and ammonium laureth sulfate to the amphoteric and / or zwitterionic surfactants b) 1: 1, 15 to 1: 5 and particularly preferably 1: 1, 15 to 1: 2.

Furthermore, it is advantageous if the cosmetic cleaning preparation according to the invention additionally contains one or more nonionic surfactants. Advantageously used nonionic surfactants are:

 Fatty acid alkanolamides of the general formula (II)

wherein R is a linear or branched, saturated or unsaturated alkyl or alkenyl radical having 8 to 24 carbon atoms, R'je are a hydrogen atom or a - (CH 2) _n OH group, in which n can take the numbers 2 or 3, with with the proviso that at least one of the groups R 'is a - (CH 2) _n OH group, for example cocamide MEA / DEA / MIPA;

 Addition products of ethylene oxide to fatty acid alkanolamides

 Ce-Cso-Fettsäuremono- and / or diester of addition products of 1 to 50 moles of ethylene oxide with glycerol;

 Addition products of 2 to 50 moles of ethylene oxide and / or 0 to 5 moles of propylene oxide with linear or branched fatty alcohols having 8 to 30 carbon atoms, to

 Fatty acids having 8 to 30 carbon atoms and alkylphenols having 8 to 15

 Carbon atoms in the alkyl group; and

 Alkyl polyglycosides, such as lauryl glycoside, decyl glycoside and cocoglycoside.

It is particularly advantageous if the nonionic surfactants cocoglycoside is included.

Advantageously, the proportion of nonionic surfactants, in particular the proportion of cocoglycoside previously mentioned as particularly advantageous, in the inventive

Cleaning preparation 0.05 wt .-% to 0.5 wt .-% and preferably 0.075 wt .-% to 0.3 wt .-%, based on the total weight of the cleaning preparation.

By using the nonionic surfactants according to the invention, in particular by using the nonionic surfactants in a proportion of 0.075 wt .-% to 0.3 wt .-%, based on the total weight of the cleaning preparation, the foam formation of the cleaning preparation is promoted. In addition, such an employment of

nonionic surfactants to increase the viscosity of the cleaning preparation. Moreover, it is advantageous if the total proportion of all surfactants in the cleaning preparation according to the invention less than 18 wt .-%, preferably less than 16 wt .-% and particularly preferably less than 15 wt .-%, based on the

Total weight of the cleaning preparation is.

In a second preferred embodiment of the invention, the cosmetic cleansing preparation according to the invention contains

 a) one or more anionic surfactants, preferably selected from the group of

 anionic surfactants according to the formula (I):

R0 _(CH2 CH20) x- (CH2-CHR ¹ 0) y (CH2CH20) z-S0 ₃ - M ⁺ (I) characterized in that

 R is a linear or branched Ce-C-alkyl radical or mixtures of different linear or branched Ce-Cie-alkyl radicals;

R ^{1 is} methyl, ethyl or mixtures thereof;

M ⁺ is a cation selected from the group consisting of alkali metals, NH ₄ ^+, and HNR ² ₃ ^+, wherein R ² is selected from the group consisting of linear or branched alkyl, CH2CH2OH, and CH ₂ CH (OH) CH _3;

 x is an integer number in the range of 0-3;

 y is an integer number in the range 0-10; and

 z is an integer number in the range 0-30;

 b) one or more amphoteric and / or zwitterionic surfactants, preferably selected from the group Sodium Cocoamphoacetate, Disodium Cocoamphodiacetate, Sodium Cocoamphopropionate, Disodium Cocoamphodipropionate, Coco Betaine, Lauryl Betaine and / or Cocamidopropylbetaine; and

 c) polyquaternium-6;

characterized in that the weight ratio of the anionic surfactants a) to the amphoteric and / or zwitterionic surfactants b) 1: 1 to 1:10, preferably 1: 1, 1 to 1: 8, more preferably 1: 1, 15 to 1: 5 and especially preferred is 1: 1, 15 to 1: 2;

and that the total amount of all surfactants in the cleaning preparation according to the invention is less than 18 wt .-%, preferably less than 16 wt .-% and particularly preferably less than 15 wt .-%, based on the total weight of the cleaning preparation is.

Within this second embodiment, it is particularly preferred if the

Cosmetic cleaning preparation according to the invention, in each case based on the

Total weight of the cleaning preparation, a) one or more anionic surfactants according to the general formula (I):

R0 _(CH2 CH20) x- (CH2-CHR ¹ 0) y (CH2CH20) z-S0 ₃ - M ⁺ (I) characterized in that

 R is a linear or branched Ce-C-alkyl radical or mixtures of different linear or branched Cs-Cis-alkyl radicals;

R ^{1 is} methyl, ethyl or mixtures thereof;

M ⁺ is a cation selected from the group consisting of alkali metals, NH ₄ ⁺ and HNR ^{+ 2} is 3, wherein R ² is selected from the group consisting of linear or branched alkyl groups, CH ₂ CH ₂ OH and CH ₂ CH (OH) CH ₃ ;

 x is an integer number in the range of 0-3;

 y is an integer number in the range 0-10; and

 z is an integer number in the range 0-30;

 b) 4 wt .-% to 17 wt .-% and preferably 5.5 wt .-% to 13 wt .-% of one or more amphoteric and / or zwitterionic surfactants selected from the group Sodium Cocoamphoacetate, Disodium Cocoamphodiacetate, Sodium Cocoamphopropionate , Disodium cocoamphodipropionate, coco betaine, lauryl betaine and / or

 cocamidopropyl; and

 c) 0.2 wt .-% to 3 wt .-%, preferably 0.5 wt .-% to 2.5 wt .-% and particularly preferably 0.75 wt .-% to 2 wt .-% Polyquaternium-6 ;

characterized in that the weight ratio of the anionic surfactants a) to the amphoteric and / or zwitterionic surfactants b) 1: 1 to 1:10, preferably 1: 1, 1 to 1: 8, more preferably 1: 1, 15 to 1: 5 and especially preferred is 1: 1, 15 to 1: 2;

and that the total proportion of all surfactants in the cleaning preparation according to the invention is less than 18 wt .-%, preferably less than 16 wt .-% and particularly preferably less than 15 wt .-%.

Particularly preferred cosmetic cleaning preparations according to the invention within the second embodiment contain, in each case based on the total weight of the cleaning preparation,

 a) Sodium Laureth Sulfate and / or Ammonium Laureth Sulfate;

 b) 5.5% to 13% by weight of one or more amphoteric and / or zwitterionic surfactants selected from the group of sodium cocoamphoacetate, disodium

 Cocoamphodiacetate, sodium cocoamphopropionate, disodium

 Cocoamphodipropionates, coco betaines, lauryl betaines and / or

 cocamidopropyl; and

c) from 0.5% to 2.5% by weight, preferably from 0.75% to 2% by weight of polyquaternium-6; characterized in that no further anionic surfactants and no further amphoteric and / or zwitterionic surfactants are contained and that the

Weight ratio of sodium laureth sulfate and ammonium laureth sulfate to the amphoteric and / or zwitterionic surfactants b) is 1: 1, 15 to 1: 5 and especially preferably 1: 1, 15 to 1: 2;

and that the total proportion of all surfactants in the cleaning preparation according to the invention is less than 18 wt .-%, preferably less than 16 wt .-% and particularly preferably less than 15 wt .-%.

In a third preferred embodiment of the invention, the cosmetic cleansing preparation according to the invention contains

 a) one or more anionic surfactants, preferably selected from the group of

 anionic surfactants according to the formula (I):

R0 (CH2CH20) x- (CH2-CHR ¹ 0) y (CH 2 CH ₂ 0) z-S03- M ⁺ (I) characterized in that

 R is a linear or branched Ca-C-is-alkyl radical or mixtures of different linear or branched Ce-C-he-alkyl radicals;

R ^{1 is} methyl, ethyl or mixtures thereof;

M ⁺ is a cation selected from the group consisting of alkali metals, NH ₄ ^+, and HNR ² 3 ^+, wherein R ² is selected from the group consisting of linear or branched alkyl, CH2CH2OH, and CH ₂ CH (OH) CH _3;

 x is an integer number in the range of 0-3;

 y is an integer number in the range 0-10; and

 z is an integer number in the range 0-30;

 b) one or more amphoteric and / or zwitterionic surfactants, preferably selected from the group Sodium Cocoamphoacetate, Disodium Cocoamphodiacetate, Sodium Cocoamphopropionate, Disodium Cocoamphodipropionate, Coco Betaine, Lauryl Betaine and / or Cocamidopropylbetaine; and

 c) Polyquaternium-6, wherein the polyquaternium-6 polymers are characterized in that they have an average molecular weight (molecular weight) of 50,000 g / mol to 800,000 g / mol, preferably 100,000 g / mol to 500,000 g / mol and particularly preferably 120,000 g have / mol to 200000 g / mol;

characterized in that the weight ratio of the anionic surfactants a) to the amphoteric and / or zwitterionic surfactants b) 1: 1 to 1:10, preferably 1: 1, 1 to 1: 8, more preferably 1: 1, 15 to 1: 5 and especially preferred is 1: 1, 15 to 1: 2;

and that the total proportion of all surfactants in the cleaning preparation according to the invention less than 18 wt .-%, preferably less than 16 wt .-% and particularly preferably less than 15 wt .-%, based on the total weight of the cleaning preparation is.

Within this third embodiment, it is particularly preferred if the

Cosmetic cleaning preparation according to the invention, in each case based on the

Total weight of the cleaning preparation,

 a) one or more anionic surfactants according to the general formula (I):

R0 _(CH2 CH20) x- (CH2-CHR ¹ 0) y (CH2CH20) z-S0 ₃ - M ⁺ (I) characterized in that

 R is a linear or branched Ce-C-alkyl radical or mixtures of different linear or branched Cs-Cis-alkyl radicals;

R ^{1 is} methyl, ethyl or mixtures thereof;

M ⁺ is a cation selected from the group consisting of alkali metals, NH ₄ ⁺ and HNR ^{+ 2} is _3, wherein R ² is selected from the group consisting of linear or branched alkyl groups, CH ₂ CH ₂ OH and CH ₂ CH (OH) CH ₃ ;

 x is an integer number in the range of 0-3;

 y is an integer number in the range 0-10; and

 z is an integer number in the range 0-30;

 b) 4 wt .-% to 17 wt .-% and preferably 5.5 wt .-% to 13 wt .-% of one or more amphoteric and / or zwitterionic surfactants selected from the group Sodium Cocoamphoacetate, Disodium Cocoamphodiacetate, Sodium Cocoamphopropionate , Disodium cocoamphodipropionate, coco betaine, lauryl betaine and / or

 cocamidopropyl; and

 c) 0.2 wt .-% to 3 wt .-%, preferably 0.5 wt .-% to 2.5 wt .-% and particularly preferably 0.75 wt .-% to 2 wt .-% Polyquaternium-6 wherein the Polyquaternium-6 polymers are characterized in that they have an average molecular weight (molecular weight) of 100000 g / mol to 500000 g / mol and particularly preferably 120000 g / mol to 200000 g / mol;

characterized in that the weight ratio of the anionic surfactants a) to the amphoteric and / or zwitterionic surfactants b) 1: 1 to 1:10, preferably 1: 1, 1 to 1: 8, more preferably 1: 1, 15 to 1: 5 and especially preferred is 1: 1, 15 to 1: 2;

and that the total proportion of all surfactants in the cleaning preparation according to the invention is less than 18 wt .-%, preferably less than 16 wt .-% and particularly preferably less than 15 wt .-%. Particularly preferred cosmetic cleaning preparations according to the invention within the third embodiment contain, in each case based on the total weight of the cleaning preparation,

 a) Sodium Laureth Sulfate and / or Ammonium Laureth Sulfate;

 b) 5.5% to 13% by weight of one or more amphoteric and / or zwitterionic surfactants selected from the group of sodium cocoamphoacetate, disodium

 Cocoamphodiacetate, sodium cocoamphopropionate, disodium

 Cocoamphodipropionates, coco betaines, lauryl betaines and / or

 cocamidopropyl; and

 c) 0.5% to 2.5% by weight, preferably 0.75% to 2% by weight of polyquaternium-6, wherein the polyquaternium-6 polymers are characterized by having an average molecular weight (Molecular weight) of 100,000 g / mol to 500,000 g / mol and particularly preferably 120,000 g / mol to 200,000 g / mol;

characterized in that no further anionic surfactants and no further amphoteric and / or zwitterionic surfactants are contained and that the

Weight ratio of sodium laureth sulfate and ammonium laureth sulfate to the amphoteric and / or zwitterionic surfactants b) is 1: 1, 15 to 1: 5 and especially preferably 1: 1, 15 to 1: 2;

and that the total proportion of all surfactants in the cleaning preparation according to the invention is less than 18 wt .-%, preferably less than 16 wt .-% and particularly preferably less than 15 wt .-%.

It is furthermore advantageous if the cosmetic cleansing composition according to the invention comprises water as cosmetic carrier in a proportion of 50% by weight to 90% by weight, preferably 70% by weight to 85% by weight, based on the total weight of the cosmetic

Cleaning preparation containing.

For thickening the cleaning preparations according to the invention, for example for the stabilization of particles, it is optionally possible to use further polymers which can be selected from the group of the polysaccharides or their derivatives, eg. B. hydroxypropylmethylcellulose and / or advantageously from the group of polyacrylates, preferably a polyacrylate from the group of the so-called carbopols, for example Carbopols types 980, 981, 1382, 2984, 5984, each individually or in combination.

Furthermore, according to the invention the use of thickeners selected from the group PEG-150 / stearyl alcohol / SMDI copolymer, PEG-150 distearate, PEG-200 glyceryl tallowate, PEG-200 Hydrogenated Glyceryl Palmate, PEG-40 Hydrogenated Castor Oil and / or PEG-90 Glyceryl Isostearate.

Furthermore, it is also possible, although not preferred, to thicken the cleaning preparations according to the invention by a combination of sodium chloride and citric acid and / or salts of citric acid. In this case, sodium chloride is contained in a proportion of 0.5 wt .-% to 4 wt .-%, preferably 1, 5 wt .-% to 3 wt .-%, based on the total weight of the cleaning preparation. Citric acid and / or salts of citric acid are present at a level of from 0.2% by weight to 1.0% by weight, preferably from 0.35% by weight to 0.6% by weight, based on the total weight of the Cleaning preparation included. Advantageously, the weight ratio of citric acid and / or salts of

Citric acid to sodium chloride 1: 2 to 1:10, preferably 1: 3 to 1: 6.

Furthermore, it is advantageous according to the invention if the thickener PEG-200 Hydrogenated Glyceryl Palmate, PEG-40 Hydrogenated Castor Oil and / or PEG-90 glyceryl isostearates are included, with the exclusive use of PEG-40 Hydrogenated Castor Oil is preferred.

Advantageously, the proportion of PEG-200 is Hydrogenated Glyceryl Palmate, PEG-40

Hydrogenated castor oil and / or PEG-90 glyceryl isostearates 0.1% by weight to 1.5% by weight, preferably 0.2% by weight to 1.3% by weight, particularly preferably 0.5% by weight .-% to 1 wt .-%, based on the total weight of the cleaning preparation. It is particularly advantageous if of the group consisting of PEG-200 Hydrogenated Glyceryl Palmate, PEG-40 Hydrogenated Castor Oil and PEG-90 Glyceryl Isostearate exclusively PEG-40

Hydrogenated Castor Oil is contained and the proportion of PEG-40 Hydrogenated Castor Oil 0.4 wt .-% to 0.8 wt .-%, based on the total weight of the cosmetic

Cleaning preparation, amounts.

For preserving the present cosmetic cleaning preparations, the preservatives commonly used in cosmetics can be used. These include, for example, parabens such as methylparaben, propylparaben, ethylparaben and butylparaben. However, it is also desirable to use acid-based preservatives which are used in the food industry. These include, for example, benzoic acid and / or salicylic acid and / or salts thereof.

Cleaning preparations having a pH of less than pH 6 are preferred according to the invention, cleaning preparations having a pH of from 4 to 4.8 being according to the invention are particularly preferred. The adjustment of the pH can be carried out in the manner customary in the cosmetic industry. However, the use of is preferred

Citric acid and sodium hydroxide to adjust the required pH.

The cleaning preparations according to the invention may i.a. Opacifier included. These are insoluble in water, usually microparticulate substances that reflect the light particularly well and give the cleaning preparations a milky or opaque appearance. Opacifiers according to the invention are styrene / acrylates copolymer, glycol distearate, glyceryl stearate or PEG-3 distearate.

The average molecular weight of Polyquaternium-6 polymers can be determined according to the invention via light scattering.

Advantageous cleaning preparations according to the invention are further characterized

in that they contain geraniol, citronellol and / or limonene.

The cosmetic cleansing preparations according to the invention may further contain cosmetic auxiliaries and active ingredients, such as are conventionally used in such preparations, eg. As further active ingredients, preservatives, preservatives, bactericides, lipids, dyes and color pigments, thickeners, moisturizing and / or moisturizing substances or other conventional ingredients of a cosmetic or dermatological formulation such as polyols, foam stabilizers, organic solvents or silicone derivatives, if the addition of the required properties

are not impaired or excluded in terms of stability.

Comparative experiments and examples

 The following examples are intended to illustrate the present invention without restricting it. Unless stated otherwise, all quantities, proportions and percentages are based on the weight and the total quantity or on the total weight of the preparations.

Pigskin Infektionsassav

 Comparative experiments using a porcine skin infection assay were performed. For this purpose, the invention listed in the following tables

Example recipe (Example 1) in comparison to non-inventive example formulations (Vgl.1 to Vgl.2) examined. In addition, a control K + (water) by means of a

Porcine skin assay examined.

 Commercial product Flocare C106 from FA. SNF SAS, 150000 g / mol perfume containing geraniol, citronellol and limonene

¹ commercial product Flocare C106 from FA. SNF SAS, 150000 g / mol

2Parfum containing geraniol, citronellol and limonene

For the study, the bacterium C. jeikeium (DSM 7171) was streaked out of an EN 12353 cryotube on an agar plate and incubated at 30 ° C for 48 hours. Of the grown bacteria, a second passage was called

Liquid culture in AC medium (37 g brain heart boullion, 5 g glucose, 1 mL polysorbate 80 / Tween®80 made up to 1 L with H2O).

The liquid culture was adjusted to a cell count of 10 ⁵ after an optical density determination (Eppendorf BioPhotometer at 600 nm) and diluted 1: 8 with thickened medium (AC medium + 0.2% agar). This bacterial suspension was then used for the test.

The test was carried out according to the following description:

 The pigskin was trimmed to a size of 9.5 cm x 3.5 cm.

Subsequently, this was sonicated in a solution consisting of 15% water and 85% ethanol for 30 minutes in an ultrasonic bath to kill the skin's own germs. Thereafter, the skin was removed from the solution and dried for 15 minutes at 21 ° C and a humidity of 50%. Subsequently, 166 ml of the preparations to be examined and 166 ml of water were applied to the skin and distributed on this with a silicone brush. After 20 minutes, the skin was rinsed for 2 minutes with water (36 ° C 10001 / h). After 15 minutes dry at 21 ° C and a humidity of 50% were 415 mI the

Bacterial suspension applied to the skin and distributed. After an incubation period of one hour at 21 ° C. and 50% atmospheric humidity, the bacteria were made up with a rinsing solution (rinsing solution: 12.5 g Na ₂ HPO ₄ × 2H ₂ O, 0.64 g KH ₂ PO ₄ , 1 g Triton X-100 made up to 1 L with H ₂ O) (30 seconds, 3 times 1 ml) rinsed off. 200 ml of the rinsed solutions are pipetted into 800 ml of neutralization medium (1 g peptone, 8.5 g sodium chloride, 30 g Tween® 80, 30 g saponin, 1 g L-histidine, 3 g lecithin, 5 g sodium thiosulfate made up to 1 L with H2O). These Dilutions were plated by means of a spiral plate on agar plates and incubated at 30 ° C for 48 hours at a humidity of 50%, then the germ count was determined using the Countermate. See also: LW Bush, LM Benson and JH White "Pig Skin as Test Substrate for Evaluating Topical Antimicrobial Activity" Journal of Clinical Microbiology, Sept. 1986, p. 343-348.

In addition to the examination of the example formulations, reference measurements were carried out in which water was applied to the pigskin as the preparation to be examined. The reduction factor for the examined cosmetic

Cleaning preparations are obtained by dividing the germ count of the reference measurement by the germ number of the respective measurement of the example formulations.

The higher the reduction factor, the stronger the antimicrobial effect caused by deposition of Polyquaternium-6 on the skin.

The determined reduction factors are shown in Figure 1. In addition, the reduction factors are given in the tables with the example formulations. On the basis of this, it is more than obvious that preparation Bsp.1 according to the invention shows a significantly improved bacterial reduction. By choosing the weight ratios according to the invention, a deposition of polyquaternium-6 on the pigskin takes place during the washing process. As a result, an improved bacterial reduction is achieved for the cleaning preparation according to the invention. The comparative examples, which have other non-inventive weight ratios for the anionic and amphoteric and / or zwitterionic surfactants, show virtually no antimicrobial activity.

 Commercial product Flocare C106 from FA. SNF SAS, 150000 g / mol perfume containing geraniol, citronellol and limonene

Claims

claims  1. Cosmetic cleaning preparation containing  a) one or more anionic surfactants,  b) one or more amphoteric and / or zwitterionic surfactants, and  c) polyquaternium-6;  characterized in that the weight ratio of the anionic surfactants to the amphoteric and / or zwitterionic surfactants 1: 1 to 1: 10, preferably 1: 1, 1 to 1: 8, more preferably 1: 1, 15 to 1: 5 and particularly preferred 1: 1, 15 to 1: 2. 2. Cosmetic cleaning preparation according to claim 1, characterized in that the anionic surfactants from the group of anionic surfactants according to the formula (I): R0 _(CH2 CH20) z S0 ₃ x- (CH2-CHR ¹ 0) y (CH2CH20) - M ⁺ (I) can be selected,  characterized in that  R is a linear or branched Ce-C-alkyl radical or mixtures of different linear or branched Cs-Cis-alkyl radicals; R ^{1 is} methyl, ethyl or mixtures thereof; M ⁺ is a cation selected from the group consisting of alkali metals, NH ₄ ^+, and HNR ² 3 ^+, wherein R ² is selected from the group consisting of linear or branched alkyl, CH2CH2OH, and CH ₂ CH (OH) CH _3;  x is an integer number in the range of 0-3;  y is an integer number in the range 0-10; and  z is an integer number in the range 0-30;  and preferably sodium laureth sulfates and / or ammonium laureth sulfates are contained. 3. Cosmetic cleaning preparation according to one of the preceding claims  characterized in that the proportion of anionic surfactants in the  0.1% by weight to 12% by weight, preferably 2% by weight to 10% by weight and particularly preferably 3% by weight to 8% by weight, based on the total weight of the cleaning preparation according to the invention , is. 4. Cosmetic cleaning preparation according to one of the preceding claims characterized in that as amphoteric and / or zwitterionic surfactants sodium cocoamphoacetate, disodium cocoamphodiacetate, sodium cocoamphopropionate, Disodium cocoamphodipropionates, coco betaines, lauryl betaines and / or cocamidopropyl betaine are included, cocamidopropyl betaine being preferred. 5. Cosmetic cleaning preparation according to one of the preceding claims  characterized in that the proportion of amphoteric and / or zwitterionic surfactants in the cosmetic cleaning preparation according to the invention 3 wt .-% to 20 wt .-%, preferably 4 wt .-% to 17 wt .-% and particularly preferably 5.5 wt. -% to 13 wt .-%, based on the total weight of the cleaning preparation is. 6. Cosmetic cleaning preparation according to one of the preceding claims  characterized in that polyquaternium-6 is characterized in that the polyquaternium-6 polymers have an average molecular weight (molecular weight) of 50,000 g / mol to 800,000 g / mol, preferably 100,000 g / mol to 500,000 g / mol and particularly preferably 120,000 g / mol to 200000 g / mol. 7. Cosmetic cleaning preparation according to one of the preceding claims  characterized in that Polyquaternium-6 in a proportion of 0.2 wt .-% to 3 wt .-%, preferably 0.5 wt .-% to 2.5 wt .-% and particularly preferably 0.75 wt .-% up to 2% by weight, based on the total weight of the cosmetic  Cleaning preparation, is included. 8. Cosmetic cleaning preparation according to one of the preceding claims  characterized in that one or more nonionic surfactants are included. 9. Cosmetic cleaning preparation according to claim 8, characterized in that the nonionic surfactants are selected from the group of  Fatty acid alkanolamides of the general formula (II)

wherein R is a linear or branched, saturated or unsaturated alkyl or alkenyl radical having 8 to 24 carbon atoms, R'je are a hydrogen atom or a - (CH 2) _n OH group, in which n can take the numbers 2 or 3, with the Provided that at least one of the groups R 'is a - (CH 2) _n OH group; Addition products of ethylene oxide to fatty acid alkanolamides;  Ce-Cso-Fettsäuremono- and / or diester of addition products of 1 to 50 moles of ethylene oxide with glycerol;  Addition products of 2 to 50 mol of ethylene oxide and / or 0 to 5 mol of propylene oxide to linear or branched fatty alcohols having 8 to 30  Carbon atoms, fatty acids having 8 to 30 carbon atoms and alkylphenols having 8 to 15 carbon atoms in the alkyl group; and  - Alkyl polyglycosides. 10. Cosmetic cleaning preparation according to one of claims 8 to 9 characterized  characterized in that the proportion of nonionic surfactants, in particular the proportion of coco-glucosides, in the cleaning preparation according to the invention 0.05 wt .-% to 0.5 wt .-% and preferably 0.075 wt .-% to 0.3 wt. %, based on the total weight of the cleaning preparation is. 1 1. Cosmetic cleaning preparation according to one of the preceding claims  characterized in that the total amount of all surfactants in the cleaning preparation according to the invention less than 18 wt .-%, preferably less than 16 wt .-% and particularly preferably less than 15 wt .-%, based on the total weight of the cleaning preparation is. 12. Cosmetic cleaning preparation according to one of the preceding claims, characterized in that water in a proportion of 70 wt .-% to 85 wt%, based on the total weight of the cosmetic cleaning preparation, is included. 13. Cosmetic cleaning preparation according to one of the preceding claims  characterized in that PEG-200 Hydrogenated Glyceryl Palmate, PEG-40 Hydrogenated Castor Oil and / or PEG-90 Glyceryl Isostearate are included and that the proportion of PEG-200 Hydrogenated Glyceryl Palmate, PEG-40 Hydrogenated Castor Oil and / or PEG- 90 glyceryl isostearates 0.1% by weight to 1.5% by weight, preferably 0.2% by weight to 1.3% by weight, particularly preferably 0.5% by weight to 1% by weight %, based on the total weight of the cleaning preparation is. 14. Use of a cosmetic cleaning preparation according to one of preceding claims for the reduction of the bacterial counts of Corynebacterium jeikeium, Staphylococcus epidermidis and / or Staphylococcus aureus on the skin. 15. A process for the deposition of Polyquaternium-6 on the skin, characterized in that a cosmetic cleaning preparation according to any one of claims 1 to 13 is applied to wet skin and rinsed again within a period of 5 seconds to 5 minutes from the skin with water.