WO2019036833A1 - Method and apparatus for capturing three-dimensional dynamic magnetic resonance imaging, device, and storage device - Google Patents
Method and apparatus for capturing three-dimensional dynamic magnetic resonance imaging, device, and storage device Download PDFInfo
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- WO2019036833A1 WO2019036833A1 PCT/CN2017/098255 CN2017098255W WO2019036833A1 WO 2019036833 A1 WO2019036833 A1 WO 2019036833A1 CN 2017098255 W CN2017098255 W CN 2017098255W WO 2019036833 A1 WO2019036833 A1 WO 2019036833A1
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
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- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
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- G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
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- the invention belongs to the field of dynamic nuclear magnetic resonance imaging technology, and in particular relates to a method, a device, a device and a storage medium for collecting three-dimensional dynamic magnetic resonance imaging.
- Magnetic Resonance Imaging has the advantages of no ionizing radiation, multi-contrast imaging, high soft tissue contrast, and has become an important tool for clinical medical examination.
- the acquired magnetic resonance analog signals are converted into digital signals and filled into k-space, and then the k-space data is reconstructed to obtain a magnetic resonance image.
- the k-space also known as Fourier space, is the fill space of the original digital data of the magnetic resonance information with spatially located encoded information.
- Three-dimensional dynamic magnetic resonance imaging is a technique for tracking and imaging the dynamic physiological processes or drug metabolism processes of human tissues and organs by using magnetic resonance technology.
- the basic principle of 3D dynamic magnetic resonance imaging is to generate a series of time-dependent k-space data by repeatedly acquiring the same imaging space. By reconstructing these data, time-dependent magnetic resonance images can be obtained.
- dynamic physiological processes such as tissue and organ (such as heartbeat, drug metabolism, etc.) can be provided.
- a series of quantitative or semi-quantitative parameters can be obtained, which reflect the biological and pathophysiological information during the development of the lesion, and are of great value for research and diagnosis.
- the acquisition methods of 3D dynamic magnetic resonance imaging mainly include three-dimensional Cartesian acquisition, three-dimensional radial acquisition, hybrid acquisition of radial and Cartesian, etc. These acquisition methods are based on repeated acquisition of some or all of the k-space data to achieve dynamic Imaging.
- the coding in three directions of k-space is completed by layer selection gradient, phase encoding gradient and frequency encoding gradient to realize the filling of three-dimensional k-space data.
- the three-dimensional radial acquisition method achieves the filling of the three-dimensional spherical k-space by simultaneously applying appropriate gradients in three directions of k-space. Both methods need to capture all k-spaces when reconstructing a set of 3D images.
- the inter-data results in a very low temporal resolution of the obtained three-dimensional dynamic magnetic resonance image.
- the hybrid acquisition method combining radial and Cartesian generally adopts the acquisition method of radial trajectory based on golden proportional angle in two-dimensional plane, and adopts Cartesian acquisition in the third dimension.
- This method can be combined with retrospective reconstruction technology. To improve the time resolution to a certain extent, but it is necessary to perform multiple repeated acquisitions, the scanning time is increased, the continuity of the dynamic image is not high, and the method is limited by the acquisition time in the third dimension. Time resolution is difficult to further improve.
- An object of the present invention is to provide a method, a device, a device and a storage medium for acquiring three-dimensional dynamic magnetic resonance imaging, which are intended to solve the problem that the existing three-dimensional dynamic magnetic resonance imaging acquisition method needs to repeatedly collect all three-dimensional k-space data, or Repeating the acquisition of all or part of the three-dimensional k-space multiple times leads to a problem of low data collection efficiency of three-dimensional dynamic magnetic resonance imaging.
- the invention provides a method for acquiring three-dimensional dynamic magnetic resonance imaging, the method comprising the steps of:
- the collection of the k-space data is stopped, and the collected k-space data is output, otherwise, the current collection times are added, and the operation is jumped to the location.
- the step of constructing a conical surface corresponding to the current number of acquisitions is described.
- the present invention provides a three-dimensional dynamic magnetic resonance imaging acquisition apparatus, the apparatus comprising:
- a conical surface building unit configured to establish a spherical coordinate system in a k-space of the preset magnetic resonance imaging system, and construct a conical surface corresponding to the current acquisition number according to the spherical coordinate system;
- a spiral collecting unit for constructing a spiral in the conical surface according to a preset spiral trajectory function Tracking, and along the helical trajectory, acquiring k-space data through the magnetic resonance imaging system;
- the collecting data output unit is configured to stop collecting the k-space data when the current number of acquisitions reaches a preset threshold, and output the collected k-space data, otherwise, add the current collection number Operating, and triggering the conical surface building unit to perform an operation of constructing a conical surface corresponding to the current number of acquisitions.
- the present invention also provides a medical device comprising a memory, a processor, and a computer program stored in the memory and operable on the processor, the processor implementing the computer program The steps described in the acquisition method of a three-dimensional dynamic magnetic resonance imaging as described above.
- the present invention also provides a computer readable storage medium storing a computer program that, when executed by a processor, implements acquisition of a three-dimensional dynamic magnetic resonance imaging as described above Method described.
- the invention establishes a spherical coordinate system in the k-space of the preset three-dimensional dynamic magnetic resonance imaging system, constructs a conical surface corresponding to the current acquisition number according to the spherical coordinate system, and constructs a spiral trajectory in the conical surface according to the spiral trajectory function, and
- the k-space data is collected along the spiral trajectory by the magnetic resonance imaging system.
- the k-space data acquisition is continued, so that the k-space data is continuously acquired through the spherical coordinates, the conical surface and the spiral trajectory, and the approximate uniform k-space data distribution can be obtained in any acquisition time window, so that the subsequent image reconstruction data is selected. It is more free and effectively improves the data acquisition efficiency of 3D dynamic magnetic resonance imaging and the temporal resolution of 3D dynamic magnetic resonance images obtained by subsequent reconstruction.
- FIG. 1 is a flowchart showing an implementation of a method for collecting three-dimensional dynamic magnetic resonance imaging according to Embodiment 1 of the present invention
- FIG. 2 is a diagram showing an example of an elevation angle of a conical surface and an initial azimuth of a spiral locus in a spherical coordinate system in a method for acquiring a three-dimensional dynamic magnetic resonance imaging according to Embodiment 1 of the present invention
- FIG. 3 is a diagram showing an example of distribution of a spiral track continuously acquired three times and a spiral track continuously collected 300 times in a spherical coordinate system in a three-dimensional dynamic magnetic resonance imaging acquisition method according to Embodiment 1 of the present invention
- FIG. 4 is a diagram showing an example of a point distribution of a spiral track end on a virtual spherical surface after 500 consecutive acquisitions in a three-dimensional dynamic magnetic resonance imaging acquisition method according to Embodiment 1 of the present invention
- FIG. 5 is a diagram showing an example of a point distribution of a spiral track end on a virtual spherical surface in a three-dimensional dynamic magnetic resonance imaging acquisition method according to a first embodiment of the present invention, with different acquisition times, different time windows, and different time combinations;
- FIG. 6 is a schematic diagram of a preferred structure of a three-dimensional dynamic magnetic resonance imaging acquisition apparatus according to Embodiment 2 of the present invention.
- FIG. 7 is a schematic diagram of a preferred structure of a three-dimensional dynamic magnetic resonance imaging acquisition apparatus according to Embodiment 2 of the present invention.
- FIG. 8 is a schematic structural diagram of a medical device according to Embodiment 3 of the present invention.
- Embodiment 1 is a diagrammatic representation of Embodiment 1:
- FIG. 1 is a flowchart showing an implementation process of a method for collecting three-dimensional dynamic magnetic resonance imaging according to Embodiment 1 of the present invention. For convenience of description, only parts related to the embodiment of the present invention are shown, which are described in detail as follows:
- step S101 a spherical coordinate system is established in the three-dimensional k-space of the preset magnetic resonance imaging system.
- step S102 a conical surface corresponding to the current acquisition number is constructed according to the established spherical coordinate system.
- the magnetic resonance imaging system may be referred to herein as a three-dimensional dynamic magnetic resonance imaging system
- the three-dimensional k-space is the filling space of the raw data acquired by the magnetic resonance imaging system.
- the magnetic resonance imaging system acquires k-space data (that is, collects the original data used to fill the k-space)
- three-dimensional k A spherical coordinate system is established in the space to acquire k-space data in the k-space of the three-dimensional sphere.
- a conical surface corresponding to the current acquisition number is first established in the spherical coordinate system, and specifically, the current collection times may be calculated according to a preset two-dimensional golden division ratio coefficient.
- the elevation angle of the corresponding conical surface in the spherical coordinate system is based on the elevation angle, and the origin of the spherical coordinate system is the apex of the conical surface, and the conical surface corresponding to the current acquisition number is constructed.
- the formula for calculating the elevation angle of the conical surface in the spherical coordinate system may be:
- step S103 a spiral trajectory is constructed in the conical surface according to a preset spiral trajectory function, and k-space data is acquired by the magnetic resonance imaging system along the spiral trajectory.
- a spiral trajectory may be constructed on the conical surface according to a preset spiral trajectory function, specifically, according to a two-dimensional golden section scaling coefficient.
- the formula for calculating the initial azimuth of the spiral trajectory in the spherical coordinate system is:
- ⁇ 2 is one of the two-dimensional golden section scale coefficients
- ⁇ 2 0.4656.
- the magnetic separation resonance imaging system performs k-space data acquisition along the spiral trajectory, thereby completing one acquisition of k-space data.
- the spiral trajectory function is not limited here, and a three-dimensional spiral trajectory curve function suitable for cone surface acquisition can be adopted according to actual conditions and requirements.
- the elevation angle ⁇ n of the conical surface in the spherical coordinate system and the initial azimuth angle of the spiral trajectory on the conical surface in the spherical coordinate system are given in Fig. 2 .
- k x k y k z denotes a spherical coordinate system, and the dotted line portion is a virtual sphere in order to more clearly express the elevation angle and the initial azimuth angle.
- step S104 it is detected whether the current number of acquisitions reaches a preset threshold.
- step S104 when it is detected that the current number of acquisitions reaches the preset threshold, the collection of the k-space data may be considered to be completed, and step S104 is performed; otherwise, step S105 is performed.
- step S105 the acquisition of the k-space data is stopped, and the acquired k-space data is output.
- the acquisition of k-space data has been completed, and the acquired k-space data is output, and the acquired k-space data can be used to reconstruct a three-dimensional dynamic magnetic resonance image, for example, first to second.
- the k-space data acquired ten times is used for reconstruction of the first-frame three-dimensional magnetic resonance image
- the k-space data acquired from the twenty-first to thirty-times is used for reconstruction of the second-frame three-dimensional magnetic resonance image, and thus is calculated, that is,
- the reconstruction of the 3D dynamic magnetic resonance image can be completed, thereby improving the continuity of the reconstructed 3D dynamic magnetic resonance image through continuous acquisition of k-space data.
- a on the left side of FIG. 3 is a spiral track that is continuously acquired three times
- b on the right side is a spiral track that is continuously collected 300 times
- a dotted line portion is a virtual sphere (used to represent a three-dimensional spherical k-space).
- Figure 4 shows the point distribution of the end of the spiral track on the virtual spherical surface after 500 consecutive acquisitions. As can be seen from Figure 4, the acquired k-space data is approximately evenly distributed in the k-space of the three-dimensional sphere.
- Figure 5 shows the distribution of the points on the virtual spherical surface at the end of the spiral path under different acquisition times, different time windows and different time combinations.
- the k acquired in any length of time (that is, the number of arbitrary acquisitions)
- the spatial data is approximately evenly distributed in the k-space of the three-dimensional sphere.
- the k-space data acquired in the time window of any position is approximately evenly distributed in the k-space of the three-dimensional sphere, and the k-space data acquired in any combination time window is in the three-dimensional sphere. Approximate uniform distribution in k-space, which makes the selection of data more convenient in subsequent image reconstruction, effectively improving the data acquisition efficiency of 3D dynamic magnetic resonance imaging and the time resolution of 3D dynamic magnetic resonance images.
- step S106 the current acquisition count is incremented, and the process proceeds to step S102.
- the current acquisition times may be added, and the process proceeds to step S102, and the construction of the conical surface and the spiral trajectory corresponding to the current acquisition times is continued. And k-space data collection.
- a spherical coordinate system is established in a three-dimensional k-space of a magnetic resonance imaging system, and a conical surface is established according to a two-dimensional golden ratio coefficient in a spherical coordinate system, and a spiral orbit on a conical surface is constructed.
- Trace, through the magnetic resonance imaging system, the k-space data is collected along the spiral trajectory.
- the acquisition of the k-space data is stopped, and the acquired k-space data is output, otherwise the current acquisition times are added.
- the construction of the conical surface, the spiral trajectory and the acquisition of the k-space data are continued, thereby realizing the continuous acquisition of the three-dimensional k-space data in the three-dimensional dynamic magnetic resonance imaging, so that the data collected in any time window is in the k-space of the three-dimensional sphere.
- the approximation is evenly distributed, which makes the selection of subsequent image reconstruction data more free, and effectively improves the data collection efficiency of 3D dynamic magnetic resonance imaging and the time resolution of 3D dynamic magnetic resonance images.
- Embodiment 2 is a diagrammatic representation of Embodiment 1:
- FIG. 6 shows a structure of a three-dimensional dynamic magnetic resonance imaging acquisition apparatus according to Embodiment 2 of the present invention. For convenience of description, only parts related to the embodiment of the present invention are shown, including:
- the conical surface construction unit 61 is configured to establish a spherical coordinate system in a three-dimensional k-space of the preset magnetic resonance imaging system, and construct a conical surface corresponding to the current acquisition number according to the spherical coordinate system.
- the spherical coordinate system is established in the three-dimensional k-space before the magnetic resonance imaging system acquires the k-space data, and the conical surface corresponding to the current acquisition number is established in the spherical coordinate system, specifically, according to the preset
- the two-dimensional golden section scale coefficient calculates the elevation angle of the conical surface corresponding to the current acquisition number in the spherical coordinate system, and according to the elevation angle, the origin of the spherical coordinate system is the apex of the conical surface, and the conical surface corresponding to the current collection number is constructed.
- the formula for calculating the elevation angle of the conical surface in the spherical coordinate system may be:
- the spiral collecting unit 62 is configured to construct a spiral trajectory in the conical surface according to a preset spiral trajectory function, and collect k-space data through the magnetic resonance imaging system along the spiral trajectory.
- a spiral trajectory may be constructed on the conical surface according to a preset spiral trajectory function, specifically, according to the two-dimensional golden section.
- the proportional coefficient calculates the initial azimuth of the spiral trajectory in the spherical coordinate system in the spherical coordinate system, and then constructs (or draws) the spiral trajectory on the conical surface according to the initial azimuth and the spiral trajectory function.
- the formula for calculating the initial azimuth of the spiral trajectory in the spherical coordinate system is:
- ⁇ 2 is one of the two-dimensional golden section scale coefficients
- ⁇ 2 0.4656.
- the magnetic separation resonance imaging system performs k-space data acquisition along the spiral trajectory, thereby completing one acquisition of k-space data.
- the spiral trajectory function is not limited here, and a three-dimensional spiral trajectory curve function suitable for cone surface acquisition can be adopted according to actual conditions and requirements.
- the collection data output unit 63 is configured to stop the acquisition of the k-space data and output the acquired k-space data when the current acquisition times reaches the preset threshold, otherwise, the current acquisition times are added, and the cone surface is triggered.
- the unit 61 performs an operation of constructing a conical surface corresponding to the current number of acquisitions.
- the k-space data when it is detected that the current number of acquisitions reaches a preset threshold, the k-space data may be collected, and the acquired k-space data may be used to reconstruct a three-dimensional dynamic magnetic resonance image, for example, the first
- the k-space data acquired from the twentieth time is used for the reconstruction of the first frame of the three-dimensional magnetic resonance image
- the k-space data acquired from the twenty-first to thirty times is used for the reconstruction of the second-frame three-dimensional magnetic resonance image.
- the acquired k-space data is approximately evenly distributed in the k-space of the three-dimensional sphere, and is within an arbitrary length of time (ie, an arbitrary number of acquisitions) and an arbitrary position time window.
- the k-space data collected in any combination time window is approximately evenly distributed in the k-space of the three-dimensional sphere, so that the data selection in the subsequent image reconstruction is more free, and the data of the three-dimensional dynamic magnetic resonance imaging is effectively improved. Acquisition efficiency, time resolution of 3D dynamic magnetic resonance images.
- the current acquisition times may be added, and the conical surface construction unit 61 is triggered to perform the conical surface corresponding to the current acquisition times.
- the conical surface building unit 61 comprises:
- the elevation angle calculation unit 711 is configured to calculate an elevation angle of the conical surface corresponding to the current acquisition number in the spherical coordinate system according to the preset two-dimensional golden section scale coefficient;
- the conical surface construction subunit 712 is configured to construct a conical surface according to the elevation angle of the conical surface in the spherical coordinate system and the origin of the spherical coordinate system as a vertex.
- the spiral collection unit 62 comprises:
- the azimuth calculating unit 721 is configured to calculate an initial azimuth of the spiral trajectory in the spherical coordinate system according to the two-dimensional golden section scaling coefficient;
- the trajectory construction unit 722 is configured to construct a spiral trajectory according to an initial azimuth and a spiral trajectory function of the spiral trajectory in the spherical coordinate system.
- a spherical coordinate system is established in a three-dimensional k-space of a magnetic resonance imaging system, and a conical surface is established according to a two-dimensional golden section scale coefficient in a spherical coordinate system, and a spiral trajectory on a conical surface is constructed, by magnetic resonance
- the imaging system performs k-space data acquisition along the spiral trajectory.
- the k-space data acquisition is stopped, and the acquired k-space data is output, otherwise the current acquisition times are added, and the cone is continued.
- the construction of surface and spiral trajectory and the acquisition of k-space data enable continuous acquisition of 3D k-space data in 3D dynamic magnetic resonance imaging, so that the data collected in any time window is approximately evenly distributed in the k-space of the three-dimensional sphere. Furthermore, the selection of subsequent image reconstruction data is more free, and the data collection efficiency of the three-dimensional dynamic magnetic resonance imaging and the temporal resolution of the three-dimensional dynamic magnetic resonance image are effectively improved.
- each unit of the three-dimensional dynamic magnetic resonance imaging acquisition device may be implemented by a corresponding hardware or software unit, and each unit may be an independent software and hardware unit, or may be integrated into a software and hardware unit. It is not intended to limit the invention.
- Embodiment 3 is a diagrammatic representation of Embodiment 3
- FIG. 8 shows the structure of a medical device according to a third embodiment of the present invention. For the convenience of description, only parts related to the embodiment of the present invention are shown.
- the medical device 8 of the embodiment of the present invention includes a processor 80, a memory 81, and is stored in the memory.
- Computer program 82 in 81 and operable on processor 80.
- the processor 80 when executing the computer program 82, implements the steps in the above-described method embodiments, such as steps S101 through S106 shown in FIG.
- processor 80 when executing computer program 82, implements the functions of the various units of the apparatus embodiments described above, such as the functions of units 61-63 shown in FIG.
- a spherical coordinate system is established in the k-space of the preset three-dimensional dynamic magnetic resonance imaging system, and a conical surface corresponding to the current acquisition number is constructed according to the spherical coordinate system, and is constructed in the conical surface according to the spiral trajectory function.
- Spiral trajectory, and k-space data is collected along the spiral trajectory by the magnetic resonance imaging system.
- the acquisition of k-space data is stopped, and the acquired k-space data is output, otherwise the jump
- the k-space data acquisition is continued, so that the k-space data is continuously acquired by the spherical coordinates, the conical surface and the spiral trajectory, and an approximately uniform k-space data distribution can be obtained in any acquisition time window, so that The selection of subsequent image reconstruction data is more free, which effectively improves the data collection efficiency of 3D dynamic magnetic resonance imaging and the temporal resolution of 3D dynamic magnetic resonance images obtained by subsequent reconstruction.
- Embodiment 4 is a diagrammatic representation of Embodiment 4:
- a computer readable storage medium storing a computer program, which when executed by a processor, implements the steps in the foregoing method embodiments, for example, FIG. Steps S101 to S106 are shown.
- the computer program when executed by the processor, implements the functions of the various units of the apparatus embodiments described above, such as the functions of units 61 through 63 shown in FIG.
- the present invention establishes a spherical coordinate system in the k-space of the preset three-dimensional dynamic magnetic resonance imaging system, and constructs a conical surface corresponding to the current acquisition number according to the spherical coordinate system, according to the spiral trajectory function, in the conical surface A spiral trajectory is constructed, and k-space data is collected along the spiral trajectory by the magnetic resonance imaging system.
- the current acquisition number of the detection channel reaches a preset threshold, the acquisition of k-space data is stopped, and the acquired k-space data is output, otherwise the hop is output.
- the k-space data acquisition is continued, so that the k-space data is continuously acquired by the spherical coordinates, the conical surface and the spiral trajectory, and the approximate uniform k-space data distribution can be obtained in any acquisition time window.
- Make subsequent images heavy The choice of data is more free, which effectively improves the data collection efficiency of 3D dynamic magnetic resonance imaging and the temporal resolution of 3D dynamic magnetic resonance images obtained by subsequent reconstruction.
- the computer readable storage medium of the embodiments of the present invention may include any entity or device capable of carrying computer program code, a recording medium such as a ROM/RAM, a magnetic disk, an optical disk, a flash memory, or the like.
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Abstract
Description
本发明属于动态核磁共振成像技术领域,尤其涉及一种三维动态磁共振成像的采集方法、装置、设备及存储介质。The invention belongs to the field of dynamic nuclear magnetic resonance imaging technology, and in particular relates to a method, a device, a device and a storage medium for collecting three-dimensional dynamic magnetic resonance imaging.
磁共振成像(Magnetic Resonance Imaging,MRI)具有无电离辐射,多对比度成像,软组织对比度高等优点,已经成为临床医学检查的一种重要工具。在磁共振成像过程中将采集到的磁共振模拟信号转换为数字信号,并填充到k空间中,再对k空间数据进行重建可得到磁共振图像。k空间也称为傅里叶空间,是带有空间定位编码信息的磁共振信息原始数字数据的填充空间。Magnetic Resonance Imaging (MRI) has the advantages of no ionizing radiation, multi-contrast imaging, high soft tissue contrast, and has become an important tool for clinical medical examination. During the magnetic resonance imaging process, the acquired magnetic resonance analog signals are converted into digital signals and filled into k-space, and then the k-space data is reconstructed to obtain a magnetic resonance image. The k-space, also known as Fourier space, is the fill space of the original digital data of the magnetic resonance information with spatially located encoded information.
三维动态磁共振成像是利用磁共振技术对人体组织器官的动态生理过程或者药物代谢过程进行跟踪成像的一种技术。三维动态磁共振成像的基本原理是通过重复地采集同一成像空间,生成一系列与时间相关的k空间数据,通过对这些数据重建可以得到与时间相关的磁共振图像,该组磁共振图像在一定程度上可以提供组织器官等动态生理过程(如心跳运动,药物代谢等)。通过对这些图像做数据分析可以获得一系列定量或半定量参数,这些参数反映了病变发生发展过程中的生物学和病理生理学信息,对研究和诊断都有重要价值。Three-dimensional dynamic magnetic resonance imaging is a technique for tracking and imaging the dynamic physiological processes or drug metabolism processes of human tissues and organs by using magnetic resonance technology. The basic principle of 3D dynamic magnetic resonance imaging is to generate a series of time-dependent k-space data by repeatedly acquiring the same imaging space. By reconstructing these data, time-dependent magnetic resonance images can be obtained. To the extent that dynamic physiological processes such as tissue and organ (such as heartbeat, drug metabolism, etc.) can be provided. By performing data analysis on these images, a series of quantitative or semi-quantitative parameters can be obtained, which reflect the biological and pathophysiological information during the development of the lesion, and are of great value for research and diagnosis.
目前,三维动态磁共振成像的采集方法主要包括三维笛卡尔采集、三维径向采集、径向与笛卡尔相结合的混合采集等,这些采集方法都是基于重复采集部分或者全部k空间数据实现动态成像。在三维笛卡尔采集中,通过选层梯度、相位编码梯度和频率编码梯度完成k空间三个方向上的编码,实现三维k空间数据的填充。三维径向采集方法通过对k空间三个方向同时施加适当的梯度实现三维球形k空间的填充。这两种方法重建一组三维图像都需要采集全部k空 间数据,导致获得的三维动态磁共振图像的时间分辨率很低。径向与笛卡尔相结合的混合采集方法一般在二维面内采用基于黄金比例角的径向轨迹的采集方式,在第三个维度上采用笛卡尔采集,该方法通过结合回顾性重建技术可以在一定程度上提高时间分辨率,但需要进行多次重复的采集才能实现,增加了扫描时间,动态图像的连续性也不高,而且由于受到第三个维度上的采集时间限制,该方法的时间分辨率难以进一步提高。At present, the acquisition methods of 3D dynamic magnetic resonance imaging mainly include three-dimensional Cartesian acquisition, three-dimensional radial acquisition, hybrid acquisition of radial and Cartesian, etc. These acquisition methods are based on repeated acquisition of some or all of the k-space data to achieve dynamic Imaging. In the three-dimensional Cartesian acquisition, the coding in three directions of k-space is completed by layer selection gradient, phase encoding gradient and frequency encoding gradient to realize the filling of three-dimensional k-space data. The three-dimensional radial acquisition method achieves the filling of the three-dimensional spherical k-space by simultaneously applying appropriate gradients in three directions of k-space. Both methods need to capture all k-spaces when reconstructing a set of 3D images. The inter-data results in a very low temporal resolution of the obtained three-dimensional dynamic magnetic resonance image. The hybrid acquisition method combining radial and Cartesian generally adopts the acquisition method of radial trajectory based on golden proportional angle in two-dimensional plane, and adopts Cartesian acquisition in the third dimension. This method can be combined with retrospective reconstruction technology. To improve the time resolution to a certain extent, but it is necessary to perform multiple repeated acquisitions, the scanning time is increased, the continuity of the dynamic image is not high, and the method is limited by the acquisition time in the third dimension. Time resolution is difficult to further improve.
发明内容Summary of the invention
本发明的目的在于提供一种三维动态磁共振成像的采集方法、装置、设备及存储介质,旨在解决由于现有的三维动态磁共振成像的采集方法需要重复采集全部的三维k空间数据、或多次重复采集全部或部分的三维k空间,导致三维动态磁共振成像的数据采集效率较低的问题。An object of the present invention is to provide a method, a device, a device and a storage medium for acquiring three-dimensional dynamic magnetic resonance imaging, which are intended to solve the problem that the existing three-dimensional dynamic magnetic resonance imaging acquisition method needs to repeatedly collect all three-dimensional k-space data, or Repeating the acquisition of all or part of the three-dimensional k-space multiple times leads to a problem of low data collection efficiency of three-dimensional dynamic magnetic resonance imaging.
一方面,本发明提供了一种三维动态磁共振成像的采集方法,所述方法包括下述步骤:In one aspect, the invention provides a method for acquiring three-dimensional dynamic magnetic resonance imaging, the method comprising the steps of:
在预设的磁共振成像系统的三维k空间中建立球坐标系,根据所述球坐标系,构建当前采集次数对应的圆锥面;Establishing a spherical coordinate system in a three-dimensional k-space of the preset magnetic resonance imaging system, and constructing a conical surface corresponding to the current acquisition number according to the spherical coordinate system;
根据预设的螺旋轨迹函数,在所述圆锥面中构建螺旋轨迹,并沿着所述螺旋轨迹,通过所述磁共振成像系统采集k空间数据;Constructing a spiral trajectory in the conical surface according to a preset spiral trajectory function, and collecting k-space data through the magnetic resonance imaging system along the spiral trajectory;
当检测到所述当前采集次数达到预设阈值时,停止所述k空间数据的采集,输出采集的所述k空间数据,否则,对所述当前采集次数进行加一操作,并跳转至所述构建当前采集次数对应的圆锥面的步骤。When it is detected that the current number of acquisitions reaches a preset threshold, the collection of the k-space data is stopped, and the collected k-space data is output, otherwise, the current collection times are added, and the operation is jumped to the location. The step of constructing a conical surface corresponding to the current number of acquisitions is described.
另一方面,本发明提供了一种三维动态磁共振成像的采集装置,所述装置包括:In another aspect, the present invention provides a three-dimensional dynamic magnetic resonance imaging acquisition apparatus, the apparatus comprising:
圆锥面构建单元,用于在预设的磁共振成像系统的k空间中建立球坐标系,根据所述球坐标系,构建当前采集次数对应的圆锥面;a conical surface building unit, configured to establish a spherical coordinate system in a k-space of the preset magnetic resonance imaging system, and construct a conical surface corresponding to the current acquisition number according to the spherical coordinate system;
螺旋采集单元,用于根据预设的螺旋轨迹函数,在所述圆锥面中构建螺旋 轨迹,并沿着所述螺旋轨迹,通过所述磁共振成像系统采集k空间数据;以及a spiral collecting unit for constructing a spiral in the conical surface according to a preset spiral trajectory function Tracking, and along the helical trajectory, acquiring k-space data through the magnetic resonance imaging system;
采集数据输出单元,用于当检测到所述当前采集次数达到预设阈值时,停止所述k空间数据的采集,输出采集的所述k空间数据,否则,对所述当前采集次数进行加一操作,并触发所述圆锥面构建单元执行构建所述当前采集次数对应的圆锥面的操作。The collecting data output unit is configured to stop collecting the k-space data when the current number of acquisitions reaches a preset threshold, and output the collected k-space data, otherwise, add the current collection number Operating, and triggering the conical surface building unit to perform an operation of constructing a conical surface corresponding to the current number of acquisitions.
另一方面,本发明还提供了一种医疗设备,包括存储器、处理器以及存储在所述存储器中并可在所述处理器上运行的计算机程序,所述处理器执行所述计算机程序时实现如上述一种三维动态磁共振成像的采集方法所述的步骤。In another aspect, the present invention also provides a medical device comprising a memory, a processor, and a computer program stored in the memory and operable on the processor, the processor implementing the computer program The steps described in the acquisition method of a three-dimensional dynamic magnetic resonance imaging as described above.
另一方面,本发明还提供了一种计算机可读存储介质,所述计算机可读存储介质存储有计算机程序,所述计算机程序被处理器执行时实现如上述一种三维动态磁共振成像的采集方法所述的步骤。In another aspect, the present invention also provides a computer readable storage medium storing a computer program that, when executed by a processor, implements acquisition of a three-dimensional dynamic magnetic resonance imaging as described above Method described.
本发明在预设的三维动态磁共振成像系统的k空间中,建立球坐标系,根据球坐标系,构建当前采集次数对应的圆锥面,根据螺旋轨迹函数,在圆锥面中构建螺旋轨迹,并通过磁共振成像系统沿着该螺旋轨迹采集k空间数据,当检测道当前采集次数达到预设阈值时,停止k空间数据的采集,输出采集的k空间数据,否则跳转至构建圆锥面的步骤,继续k空间数据的采集,从而通过球坐标、圆锥面以及螺旋轨迹实现k空间数据的连续采集,在任一采集时间窗内都可以得到近似均匀的k空间数据分布,使得后续图像重建数据的选择更为自由,有效地提高了三维动态磁共振成像的数据采集效率、以及后续重建得到的三维动态磁共振图像的时间分辨率。The invention establishes a spherical coordinate system in the k-space of the preset three-dimensional dynamic magnetic resonance imaging system, constructs a conical surface corresponding to the current acquisition number according to the spherical coordinate system, and constructs a spiral trajectory in the conical surface according to the spiral trajectory function, and The k-space data is collected along the spiral trajectory by the magnetic resonance imaging system. When the current acquisition times of the detection channel reaches a preset threshold, the acquisition of the k-space data is stopped, and the acquired k-space data is output, otherwise the step of jumping to constructing the conical surface is performed. The k-space data acquisition is continued, so that the k-space data is continuously acquired through the spherical coordinates, the conical surface and the spiral trajectory, and the approximate uniform k-space data distribution can be obtained in any acquisition time window, so that the subsequent image reconstruction data is selected. It is more free and effectively improves the data acquisition efficiency of 3D dynamic magnetic resonance imaging and the temporal resolution of 3D dynamic magnetic resonance images obtained by subsequent reconstruction.
图1是本发明实施例一提供的三维动态磁共振成像的采集方法的实现流程图;1 is a flowchart showing an implementation of a method for collecting three-dimensional dynamic magnetic resonance imaging according to Embodiment 1 of the present invention;
图2是本发明实施例一提供的三维动态磁共振成像的采集方法中球坐标系中圆锥面的仰角、螺旋轨迹的初始方位角的示例图; 2 is a diagram showing an example of an elevation angle of a conical surface and an initial azimuth of a spiral locus in a spherical coordinate system in a method for acquiring a three-dimensional dynamic magnetic resonance imaging according to Embodiment 1 of the present invention;
图3是本发明实施例一提供的三维动态磁共振成像的采集方法中连续采集3次的螺旋轨迹和连续采集300次的螺旋轨迹分别在球坐标系中的分布示例图;3 is a diagram showing an example of distribution of a spiral track continuously acquired three times and a spiral track continuously collected 300 times in a spherical coordinate system in a three-dimensional dynamic magnetic resonance imaging acquisition method according to Embodiment 1 of the present invention;
图4是本发明实施例一提供的三维动态磁共振成像的采集方法中连续采集500次后,螺旋轨迹末端在虚拟球面上的点分布的示例图;4 is a diagram showing an example of a point distribution of a spiral track end on a virtual spherical surface after 500 consecutive acquisitions in a three-dimensional dynamic magnetic resonance imaging acquisition method according to Embodiment 1 of the present invention;
图5是本发明实施例一提供的三维动态磁共振成像的采集方法中分别在不同采集次数、不同时间窗、不同时间组合下,螺旋轨迹末端在虚拟球面上的点分布的示例图;FIG. 5 is a diagram showing an example of a point distribution of a spiral track end on a virtual spherical surface in a three-dimensional dynamic magnetic resonance imaging acquisition method according to a first embodiment of the present invention, with different acquisition times, different time windows, and different time combinations;
图6是本发明实施例二提供的三维动态磁共振成像的采集装置的优选结构示意图;6 is a schematic diagram of a preferred structure of a three-dimensional dynamic magnetic resonance imaging acquisition apparatus according to Embodiment 2 of the present invention;
图7是本发明实施例二提供的三维动态磁共振成像的采集装置的优选结构示意图;以及FIG. 7 is a schematic diagram of a preferred structure of a three-dimensional dynamic magnetic resonance imaging acquisition apparatus according to Embodiment 2 of the present invention;
图8是本发明实施例三提供的医疗设备的结构示意图。FIG. 8 is a schematic structural diagram of a medical device according to Embodiment 3 of the present invention.
为了使本发明的目的、技术方案及优点更加清楚明白,以下结合附图及实施例,对本发明进行进一步详细说明。应当理解,此处所描述的具体实施例仅仅用以解释本发明,并不用于限定本发明。The present invention will be further described in detail below with reference to the accompanying drawings and embodiments. It is understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
以下结合具体实施例对本发明的具体实现进行详细描述:The specific implementation of the present invention is described in detail below in conjunction with specific embodiments:
实施例一:Embodiment 1:
图1示出了本发明实施例一提供的三维动态磁共振成像的采集方法的实现流程,为了便于说明,仅示出了与本发明实施例相关的部分,详述如下:FIG. 1 is a flowchart showing an implementation process of a method for collecting three-dimensional dynamic magnetic resonance imaging according to Embodiment 1 of the present invention. For convenience of description, only parts related to the embodiment of the present invention are shown, which are described in detail as follows:
在步骤S101中,在预设的磁共振成像系统的三维k空间中建立球坐标系。In step S101, a spherical coordinate system is established in the three-dimensional k-space of the preset magnetic resonance imaging system.
在步骤S102中,根据建立的球坐标系,构建当前采集次数对应的圆锥面。In step S102, a conical surface corresponding to the current acquisition number is constructed according to the established spherical coordinate system.
在本发明实施例中,磁共振成像系统在这里可称为三维动态磁共振成像系统,三维的k空间为磁共振成像系统采集的原始数据的填充空间。在磁共振成像系统采集k空间数据前(即采集用来填充k空间的原始数据),在三维的k 空间中建立球坐标系,以便在三维球形的k空间中进行k空间数据的采集。In an embodiment of the invention, the magnetic resonance imaging system may be referred to herein as a three-dimensional dynamic magnetic resonance imaging system, and the three-dimensional k-space is the filling space of the raw data acquired by the magnetic resonance imaging system. Before the magnetic resonance imaging system acquires k-space data (that is, collects the original data used to fill the k-space), in three-dimensional k A spherical coordinate system is established in the space to acquire k-space data in the k-space of the three-dimensional sphere.
在本发明实施例中,在进行k空间数据采集时,先在该球坐标系中建立当前采集次数对应的圆锥面,具体地,可根据预设的二维黄金分割比例系数,计算当前采集次数对应的圆锥面在该球坐标系中的仰角,再根据该仰角,并以球坐标系的原点为圆锥面的顶点,构建当前采集次数对应的圆锥面。其中,圆锥面在该球坐标系中的仰角的计算公式可为:In the embodiment of the present invention, when k-space data acquisition is performed, a conical surface corresponding to the current acquisition number is first established in the spherical coordinate system, and specifically, the current collection times may be calculated according to a preset two-dimensional golden division ratio coefficient. The elevation angle of the corresponding conical surface in the spherical coordinate system is based on the elevation angle, and the origin of the spherical coordinate system is the apex of the conical surface, and the conical surface corresponding to the current acquisition number is constructed. Wherein, the formula for calculating the elevation angle of the conical surface in the spherical coordinate system may be:
θn=arcsin(2mod(n1γ1,1)-1),其中,n1=n+i,n为当前采集次数,n为大于等于1的正整数,θn为当当前采集次数为n时,圆锥面在球坐标系中的仰角,i为预设参数,i的值可为任意自然数,γ1为二维黄金分割比例系数之一,且γ1=0.6823。θ n =arcsin(2mod(n 1 γ 1 ,1)-1), where n 1 =n+i, n is the current number of acquisitions, n is a positive integer greater than or equal to 1, and θ n is when the current number of acquisitions is n, the elevation angle of the conical surface in the spherical coordinate system, i is the preset parameter, the value of i can be any natural number, γ 1 is one of the two-dimensional golden division ratio coefficient, and γ 1 = 0.6823.
在步骤S103中,根据预设的螺旋轨迹函数,在圆锥面中构建螺旋轨迹,并沿着螺旋轨迹,通过磁共振成像系统采集k空间数据。In step S103, a spiral trajectory is constructed in the conical surface according to a preset spiral trajectory function, and k-space data is acquired by the magnetic resonance imaging system along the spiral trajectory.
在本发明实施例中,在构建好当前采集次数对应的圆锥面后,可根据预设的螺旋轨迹函数,在该圆锥面上构建螺旋轨迹,具体地,先根据二维黄金分割比例系数,计算圆锥面中的螺旋轨迹在球坐标系中的初始方位角,再根据该初始方位角和螺旋轨迹函数,在圆锥面上构建(或绘制)该螺旋轨迹。其中,螺旋轨迹在球坐标系中的初始方位角的计算公式为:In the embodiment of the present invention, after constructing the conical surface corresponding to the current acquisition number, a spiral trajectory may be constructed on the conical surface according to a preset spiral trajectory function, specifically, according to a two-dimensional golden section scaling coefficient. The initial azimuth of the spiral trajectory in the conical surface in the spherical coordinate system, and then constructing (or drawing) the spiral trajectory on the conical surface according to the initial azimuth and the spiral trajectory function. Among them, the formula for calculating the initial azimuth of the spiral trajectory in the spherical coordinate system is:
其中,为当当前采集次数为n时,螺旋轨迹在球坐标系中的初始方位角,γ2为二维黄金分割比例系数之一,且γ2=0.4656。在构建螺旋轨迹的同时,由磁选共振成像系统沿着该螺旋轨迹,进行k空间数据的采集,从而完成k空间数据的一次采集。螺旋轨迹函数在此不进行限定,可根据实际条件和需求采用适用于圆锥面采集的三维螺旋轨迹曲线函数。 among them, For the initial azimuth angle of the spiral trajectory in the spherical coordinate system when the current number of acquisitions is n, γ 2 is one of the two-dimensional golden section scale coefficients, and γ 2 = 0.4656. At the same time as constructing the spiral trajectory, the magnetic separation resonance imaging system performs k-space data acquisition along the spiral trajectory, thereby completing one acquisition of k-space data. The spiral trajectory function is not limited here, and a three-dimensional spiral trajectory curve function suitable for cone surface acquisition can be adopted according to actual conditions and requirements.
作为示例地,图2中给出了圆锥面在球坐标系中的仰角θn、圆锥面上的螺旋轨迹在球坐标系上的初始方位角kxkykz表示球坐标系,虚线部分为虚拟的球体,以便于更清晰地表示出仰角与初始方位角。As an example, the elevation angle θ n of the conical surface in the spherical coordinate system and the initial azimuth angle of the spiral trajectory on the conical surface in the spherical coordinate system are given in Fig. 2 . k x k y k z denotes a spherical coordinate system, and the dotted line portion is a virtual sphere in order to more clearly express the elevation angle and the initial azimuth angle.
在步骤S104中,检测当前采集次数是否达到预设阈值。 In step S104, it is detected whether the current number of acquisitions reaches a preset threshold.
在本发明实施例中,当检测到当前采集次数达到预设阈值时,可认为已完成k空间数据的采集,执行步骤S104,否则,执行步骤S105。In the embodiment of the present invention, when it is detected that the current number of acquisitions reaches the preset threshold, the collection of the k-space data may be considered to be completed, and step S104 is performed; otherwise, step S105 is performed.
在步骤S105中,停止k空间数据的采集,输出采集的k空间数据。In step S105, the acquisition of the k-space data is stopped, and the acquired k-space data is output.
在本发明实施例中,当前可认为已完成k空间数据的采集,输出采集的k空间数据,已采集到的k空间数据可用来重建三维动态磁共振图像,例如,将第一次到第二十次采集的k空间数据用于第一帧三维磁共振图像的重建,将第二十一次到三十次采集的k空间数据用于第二帧三维磁共振图像的重建,如此推算,即可完成三维动态磁共振图像的重建,从而通过k空间数据的连续采集,提高了重建后三维动态磁共振图像的连续性。In the embodiment of the present invention, it is currently considered that the acquisition of k-space data has been completed, and the acquired k-space data is output, and the acquired k-space data can be used to reconstruct a three-dimensional dynamic magnetic resonance image, for example, first to second. The k-space data acquired ten times is used for reconstruction of the first-frame three-dimensional magnetic resonance image, and the k-space data acquired from the twenty-first to thirty-times is used for reconstruction of the second-frame three-dimensional magnetic resonance image, and thus is calculated, that is, The reconstruction of the 3D dynamic magnetic resonance image can be completed, thereby improving the continuity of the reconstructed 3D dynamic magnetic resonance image through continuous acquisition of k-space data.
作为示例地,图3左边的a为连续采集3次的螺旋轨迹、右边的b为连续采集300次的螺旋轨迹,虚线部分为虚拟的球体(用来表示三维球形k空间)。图4为连续采集500次后,螺旋轨迹末端在虚拟球面上的点分布,从图4可看出,采集到的k空间数据在三维球体的k空间中近似均匀分布。图5中分别为不同采集次数、不同时间窗、不同时间组合下,螺旋轨迹末端在虚拟球面上的点分布,从图5可以看出,任意长度时间内(即任意采集次数)采集到的k空间数据在三维球体的k空间中近似均匀分布,任意位置时间窗内采集到的k空间数据在三维球体的k空间中近似均匀分布,任意组合时间窗内采集到的k空间数据在三维球体的k空间中近似均匀分布,从而使得后续进行图像重建时数据的选择更为自由,有效地提高了三维动态磁共振成像的数据采集效率、三维动态磁共振图像的时间分辨率。By way of example, a on the left side of FIG. 3 is a spiral track that is continuously acquired three times, b on the right side is a spiral track that is continuously collected 300 times, and a dotted line portion is a virtual sphere (used to represent a three-dimensional spherical k-space). Figure 4 shows the point distribution of the end of the spiral track on the virtual spherical surface after 500 consecutive acquisitions. As can be seen from Figure 4, the acquired k-space data is approximately evenly distributed in the k-space of the three-dimensional sphere. Figure 5 shows the distribution of the points on the virtual spherical surface at the end of the spiral path under different acquisition times, different time windows and different time combinations. It can be seen from Figure 5 that the k acquired in any length of time (that is, the number of arbitrary acquisitions) The spatial data is approximately evenly distributed in the k-space of the three-dimensional sphere. The k-space data acquired in the time window of any position is approximately evenly distributed in the k-space of the three-dimensional sphere, and the k-space data acquired in any combination time window is in the three-dimensional sphere. Approximate uniform distribution in k-space, which makes the selection of data more convenient in subsequent image reconstruction, effectively improving the data acquisition efficiency of 3D dynamic magnetic resonance imaging and the time resolution of 3D dynamic magnetic resonance images.
在步骤S106中,对当前采集次数进行加一操作,并跳转至步骤S102。In step S106, the current acquisition count is incremented, and the process proceeds to step S102.
在本发明实施例中,当当前采集次数未达到预设阈值时,可对当前采集次数进行加一操作,并跳转至步骤S102中,继续进行当前采集次数对应的圆锥面、螺旋轨迹的构建和k空间数据的采集。In the embodiment of the present invention, when the current number of acquisitions does not reach the preset threshold, the current acquisition times may be added, and the process proceeds to step S102, and the construction of the conical surface and the spiral trajectory corresponding to the current acquisition times is continued. And k-space data collection.
在本发明实施例中,在磁共振成像系统的三维k空间中建立球坐标系,在球坐标系中根据二维黄金分割比例系数,建立圆锥面并构建圆锥面上的螺旋轨 迹,通过磁共振成像系统沿着螺旋轨迹进行k空间数据的采集,当当前采集次数达到预设阈值时,停止k空间数据的采集,并输出采集的k空间数据,否则对当前采集次数进行加一操作,继续圆锥面、螺旋轨迹的构建以及k空间数据的采集,从而实现了三维动态磁共振成像中三维k空间数据的连续采集,使得任一时间窗采集到的数据在三维球形的k空间中近似均匀分布,进而使得后续图像重建数据的选择更为自由,有效地提高了三维动态磁共振成像的数据采集效率、三维动态磁共振图像的时间分辨率。In the embodiment of the present invention, a spherical coordinate system is established in a three-dimensional k-space of a magnetic resonance imaging system, and a conical surface is established according to a two-dimensional golden ratio coefficient in a spherical coordinate system, and a spiral orbit on a conical surface is constructed. Trace, through the magnetic resonance imaging system, the k-space data is collected along the spiral trajectory. When the current acquisition times reach the preset threshold, the acquisition of the k-space data is stopped, and the acquired k-space data is output, otherwise the current acquisition times are added. In one operation, the construction of the conical surface, the spiral trajectory and the acquisition of the k-space data are continued, thereby realizing the continuous acquisition of the three-dimensional k-space data in the three-dimensional dynamic magnetic resonance imaging, so that the data collected in any time window is in the k-space of the three-dimensional sphere. The approximation is evenly distributed, which makes the selection of subsequent image reconstruction data more free, and effectively improves the data collection efficiency of 3D dynamic magnetic resonance imaging and the time resolution of 3D dynamic magnetic resonance images.
实施例二:Embodiment 2:
图6示出了本发明实施例二提供的三维动态磁共振成像的采集装置的结构,为了便于说明,仅示出了与本发明实施例相关的部分,其中包括:FIG. 6 shows a structure of a three-dimensional dynamic magnetic resonance imaging acquisition apparatus according to Embodiment 2 of the present invention. For convenience of description, only parts related to the embodiment of the present invention are shown, including:
圆锥面构建单元61,用于在预设的磁共振成像系统的三维k空间中建立球坐标系,根据球坐标系,构建当前采集次数对应的圆锥面。The conical
在本发明实施例中,在磁共振成像系统采集k空间数据前在三维的k空间中建立球坐标系,在该球坐标系中建立当前采集次数对应的圆锥面,具体地,可根据预设的二维黄金分割比例系数,计算当前采集次数对应的圆锥面在该球坐标系中的仰角,再根据该仰角,以球坐标系的原点为圆锥面的顶点,构建当前采集次数对应的圆锥面。In the embodiment of the present invention, the spherical coordinate system is established in the three-dimensional k-space before the magnetic resonance imaging system acquires the k-space data, and the conical surface corresponding to the current acquisition number is established in the spherical coordinate system, specifically, according to the preset The two-dimensional golden section scale coefficient calculates the elevation angle of the conical surface corresponding to the current acquisition number in the spherical coordinate system, and according to the elevation angle, the origin of the spherical coordinate system is the apex of the conical surface, and the conical surface corresponding to the current collection number is constructed. .
在本发明实施例中,圆锥面在该球坐标系中的仰角的计算公式可为:In the embodiment of the present invention, the formula for calculating the elevation angle of the conical surface in the spherical coordinate system may be:
θn=arcsin(2mod(n1γ1,1)-1),其中,n1=n+i,n为当前采集次数,n为大于等于1的正整数,θn为当当前采集次数为n时,圆锥面在球坐标系中的仰角,i为预设参数,i的值可为任意自然数,γ1为二维黄金分割比例系数之一,且γ1=0.6823。θ n =arcsin(2mod(n 1 γ 1 ,1)-1), where n 1 =n+i, n is the current number of acquisitions, n is a positive integer greater than or equal to 1, and θ n is when the current number of acquisitions is n, the elevation angle of the conical surface in the spherical coordinate system, i is the preset parameter, the value of i can be any natural number, γ 1 is one of the two-dimensional golden division ratio coefficient, and γ 1 = 0.6823.
螺旋采集单元62,用于根据预设的螺旋轨迹函数,在圆锥面中构建螺旋轨迹,并沿着螺旋轨迹,通过磁共振成像系统采集k空间数据。The
在本发明实施例中,在构建好当前采集次数对应的圆锥面后,可根据预设的螺旋轨迹函数,在该圆锥面上构建螺旋轨迹,具体地,先根据二维黄金分割 比例系数,计算圆锥面中的螺旋轨迹在球坐标系中的初始方位角,再根据该初始方位角和螺旋轨迹函数,在圆锥面上构建(或绘制)该螺旋轨迹。其中,螺旋轨迹在球坐标系中的初始方位角的计算公式为:In the embodiment of the present invention, after constructing the conical surface corresponding to the current acquisition number, a spiral trajectory may be constructed on the conical surface according to a preset spiral trajectory function, specifically, according to the two-dimensional golden section. The proportional coefficient calculates the initial azimuth of the spiral trajectory in the spherical coordinate system in the spherical coordinate system, and then constructs (or draws) the spiral trajectory on the conical surface according to the initial azimuth and the spiral trajectory function. Among them, the formula for calculating the initial azimuth of the spiral trajectory in the spherical coordinate system is:
其中,为当当前采集次数为n时,螺旋轨迹在球坐标系中的初始方位角,γ2为二维黄金分割比例系数之一,且γ2=0.4656。在构建螺旋轨迹的同时,由磁选共振成像系统沿着该螺旋轨迹,进行k空间数据的采集,从而完成k空间数据的一次采集。螺旋轨迹函数在此不进行限定,可根据实际条件和需求采用适用于圆锥面采集的三维螺旋轨迹曲线函数。 among them, For the initial azimuth angle of the spiral trajectory in the spherical coordinate system when the current number of acquisitions is n, γ 2 is one of the two-dimensional golden section scale coefficients, and γ 2 = 0.4656. At the same time as constructing the spiral trajectory, the magnetic separation resonance imaging system performs k-space data acquisition along the spiral trajectory, thereby completing one acquisition of k-space data. The spiral trajectory function is not limited here, and a three-dimensional spiral trajectory curve function suitable for cone surface acquisition can be adopted according to actual conditions and requirements.
采集数据输出单元63,用于当检测到当前采集次数达到预设阈值时,停止k空间数据的采集,输出采集的k空间数据,否则,对当前采集次数进行加一操作,并触发圆锥面构建单元61执行构建当前采集次数对应的圆锥面的操作。The collection
在本发明实施例中,当检测到当前采集次数达到预设阈值时,可认为已完成k空间数据的采集,已采集到的k空间数据可用来重建三维动态磁共振图像,例如,将第一次到第二十次采集的k空间数据用于第一帧三维磁共振图像的重建,将第二十一次到三十次采集的k空间数据用于第二帧三维磁共振图像的重建,如此推算,即可完成三维动态磁共振图像的重建,从而通过k空间数据的连续采集,提高了重建后三维动态磁共振图像的连续性。In the embodiment of the present invention, when it is detected that the current number of acquisitions reaches a preset threshold, the k-space data may be collected, and the acquired k-space data may be used to reconstruct a three-dimensional dynamic magnetic resonance image, for example, the first The k-space data acquired from the twentieth time is used for the reconstruction of the first frame of the three-dimensional magnetic resonance image, and the k-space data acquired from the twenty-first to thirty times is used for the reconstruction of the second-frame three-dimensional magnetic resonance image. By this calculation, the reconstruction of the 3D dynamic magnetic resonance image can be completed, and the continuity of the reconstructed 3D dynamic magnetic resonance image is improved by the continuous acquisition of k-space data.
在本发明实施例中,在当前采集次数达到采集阈值时,采集到的k空间数据在三维球体的k空间中近似均匀分布,且任意长度时间内(即任意采集次数)、任意位置时间窗内、或者任意组合时间窗内采集到的k空间数据在三维球体的k空间中都近似均匀分布,从而使得后续进行图像重建时数据的选择更为自由,有效地提高了三维动态磁共振成像的数据采集效率、三维动态磁共振图像的时间分辨率。In the embodiment of the present invention, when the current number of acquisitions reaches the collection threshold, the acquired k-space data is approximately evenly distributed in the k-space of the three-dimensional sphere, and is within an arbitrary length of time (ie, an arbitrary number of acquisitions) and an arbitrary position time window. The k-space data collected in any combination time window is approximately evenly distributed in the k-space of the three-dimensional sphere, so that the data selection in the subsequent image reconstruction is more free, and the data of the three-dimensional dynamic magnetic resonance imaging is effectively improved. Acquisition efficiency, time resolution of 3D dynamic magnetic resonance images.
在本发明实施例中,当当前采集次数未达到预设阈值时,可对当前采集次数进行加一操作,并触发圆锥面构建单元61进行当前采集次数对应的圆锥面、构建。
In the embodiment of the present invention, when the current number of acquisitions does not reach the preset threshold, the current acquisition times may be added, and the conical
优选地,如图7所示,圆锥面构建单元61包括:Preferably, as shown in FIG. 7, the conical
仰角计算单元711,用于根据预设的二维黄金分割比例系数,计算当前采集次数对应的圆锥面在球坐标系中的仰角;以及The elevation
圆锥面构建子单元712,用于根据圆锥面在球坐标系中的仰角,以球坐标系的原点为顶点,构建圆锥面。The conical
优选地,螺旋采集单元62包括:Preferably, the
方位角计算单元721,用于根据二维黄金分割比例系数,计算圆锥面中螺旋轨迹在球坐标系中的初始方位角;以及The
轨迹构建单元722,用于根据螺旋轨迹在球坐标系中的初始方位角和螺旋轨迹函数,构建螺旋轨迹。The
在本发明实施例中,在磁共振成像系统的三维k空间中建立球坐标系,在球坐标系中根据二维黄金分割比例系数,建立圆锥面并构建圆锥面上的螺旋轨迹,通过磁共振成像系统沿着螺旋轨迹进行k空间数据的采集,当当前采集次数达到预设阈值时,停止k空间数据的采集,并输出采集的k空间数据,否则对当前采集次数进行加一操作,继续圆锥面、螺旋轨迹的构建以及k空间数据的采集,从而实现了三维动态磁共振成像中三维k空间数据的连续采集,使得任一时间窗采集到的数据在三维球形的k空间中近似均匀分布,进而使得后续图像重建数据的选择更为自由,有效地提高了三维动态磁共振成像的数据采集效率、三维动态磁共振图像的时间分辨率。In the embodiment of the present invention, a spherical coordinate system is established in a three-dimensional k-space of a magnetic resonance imaging system, and a conical surface is established according to a two-dimensional golden section scale coefficient in a spherical coordinate system, and a spiral trajectory on a conical surface is constructed, by magnetic resonance The imaging system performs k-space data acquisition along the spiral trajectory. When the current acquisition times reach the preset threshold, the k-space data acquisition is stopped, and the acquired k-space data is output, otherwise the current acquisition times are added, and the cone is continued. The construction of surface and spiral trajectory and the acquisition of k-space data enable continuous acquisition of 3D k-space data in 3D dynamic magnetic resonance imaging, so that the data collected in any time window is approximately evenly distributed in the k-space of the three-dimensional sphere. Furthermore, the selection of subsequent image reconstruction data is more free, and the data collection efficiency of the three-dimensional dynamic magnetic resonance imaging and the temporal resolution of the three-dimensional dynamic magnetic resonance image are effectively improved.
在本发明实施例中,三维动态磁共振成像的采集装置的各单元可由相应的硬件或软件单元实现,各单元可以为独立的软、硬件单元,也可以集成为一个软、硬件单元,在此不用以限制本发明。In the embodiment of the present invention, each unit of the three-dimensional dynamic magnetic resonance imaging acquisition device may be implemented by a corresponding hardware or software unit, and each unit may be an independent software and hardware unit, or may be integrated into a software and hardware unit. It is not intended to limit the invention.
实施例三:Embodiment 3:
图8示出了本发明实施例三提供的医疗设备的结构,为了便于说明,仅示出了与本发明实施例相关的部分。FIG. 8 shows the structure of a medical device according to a third embodiment of the present invention. For the convenience of description, only parts related to the embodiment of the present invention are shown.
本发明实施例的医疗设备8包括处理器80、存储器81以及存储在存储器
81中并可在处理器80上运行的计算机程序82。该处理器80执行计算机程序82时实现上述方法实施例中的步骤,例如图1所示的步骤S101至S106。或者,处理器80执行计算机程序82时实现上述装置实施例中各单元的功能,例如图6所示单元61至63的功能。The
在本发明实施例中,在预设的三维动态磁共振成像系统的k空间中建立球坐标系,根据球坐标系,构建当前采集次数对应的圆锥面,根据螺旋轨迹函数,在圆锥面中构建螺旋轨迹,并通过磁共振成像系统沿着该螺旋轨迹采集k空间数据,当检测道当前采集次数达到预设阈值时,停止k空间数据的采集,并输出采集到的k空间数据,否则跳转至构建圆锥面的步骤,继续k空间数据的采集,从而通过球坐标、圆锥面以及螺旋轨迹实现k空间数据的连续采集,在任一采集时间窗内都可以得到近似均匀的k空间数据分布,使得后续图像重建数据的选择更为自由,有效地提高了三维动态磁共振成像的数据采集效率、以及后续重建得到的三维动态磁共振图像的时间分辨率。In the embodiment of the present invention, a spherical coordinate system is established in the k-space of the preset three-dimensional dynamic magnetic resonance imaging system, and a conical surface corresponding to the current acquisition number is constructed according to the spherical coordinate system, and is constructed in the conical surface according to the spiral trajectory function. Spiral trajectory, and k-space data is collected along the spiral trajectory by the magnetic resonance imaging system. When the current number of acquisitions reaches a preset threshold, the acquisition of k-space data is stopped, and the acquired k-space data is output, otherwise the jump To the step of constructing the conical surface, the k-space data acquisition is continued, so that the k-space data is continuously acquired by the spherical coordinates, the conical surface and the spiral trajectory, and an approximately uniform k-space data distribution can be obtained in any acquisition time window, so that The selection of subsequent image reconstruction data is more free, which effectively improves the data collection efficiency of 3D dynamic magnetic resonance imaging and the temporal resolution of 3D dynamic magnetic resonance images obtained by subsequent reconstruction.
实施例四:Embodiment 4:
在本发明实施例中,提供了一种计算机可读存储介质,该计算机可读存储介质存储有计算机程序,该计算机程序被处理器执行时实现上述方法实施例中的步骤,例如,图1所示的步骤S101至S106。或者,该计算机程序被处理器执行时实现上述装置实施例中各单元的功能,例如图6所示单元61至63的功能。In an embodiment of the present invention, there is provided a computer readable storage medium storing a computer program, which when executed by a processor, implements the steps in the foregoing method embodiments, for example, FIG. Steps S101 to S106 are shown. Alternatively, the computer program, when executed by the processor, implements the functions of the various units of the apparatus embodiments described above, such as the functions of
在本发明实施例中,本发明在预设的三维动态磁共振成像系统的k空间中建立球坐标系,根据球坐标系,构建当前采集次数对应的圆锥面,根据螺旋轨迹函数,在圆锥面中构建螺旋轨迹,并通过磁共振成像系统沿着该螺旋轨迹采集k空间数据,当检测道当前采集次数达到预设阈值时,停止k空间数据的采集,并输出采集的k空间数据,否则跳转至构建圆锥面的步骤,继续k空间数据的采集,从而通过球坐标、圆锥面以及螺旋轨迹实现k空间数据的连续采集,在任一采集时间窗内都可以得到近似均匀的k空间数据分布,使得后续图像重 建数据的选择更为自由,有效地提高了三维动态磁共振成像的数据采集效率、以及后续重建得到的三维动态磁共振图像的时间分辨率。In the embodiment of the present invention, the present invention establishes a spherical coordinate system in the k-space of the preset three-dimensional dynamic magnetic resonance imaging system, and constructs a conical surface corresponding to the current acquisition number according to the spherical coordinate system, according to the spiral trajectory function, in the conical surface A spiral trajectory is constructed, and k-space data is collected along the spiral trajectory by the magnetic resonance imaging system. When the current acquisition number of the detection channel reaches a preset threshold, the acquisition of k-space data is stopped, and the acquired k-space data is output, otherwise the hop is output. Turning to the step of constructing the conical surface, the k-space data acquisition is continued, so that the k-space data is continuously acquired by the spherical coordinates, the conical surface and the spiral trajectory, and the approximate uniform k-space data distribution can be obtained in any acquisition time window. Make subsequent images heavy The choice of data is more free, which effectively improves the data collection efficiency of 3D dynamic magnetic resonance imaging and the temporal resolution of 3D dynamic magnetic resonance images obtained by subsequent reconstruction.
本发明实施例的计算机可读存储介质可以包括能够携带计算机程序代码的任何实体或装置、记录介质,例如,ROM/RAM、磁盘、光盘、闪存等存储器。The computer readable storage medium of the embodiments of the present invention may include any entity or device capable of carrying computer program code, a recording medium such as a ROM/RAM, a magnetic disk, an optical disk, a flash memory, or the like.
以上所述仅为本发明的较佳实施例而已,并不用以限制本发明,凡在本发明的精神和原则之内所作的任何修改、等同替换和改进等,均应包含在本发明的保护范围之内。 The above is only the preferred embodiment of the present invention, and is not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should be included in the protection of the present invention. Within the scope.
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