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WO2019046661A1 - Composition pharmaceutique contenant diverses formes et souches de cannabis - Google Patents

Composition pharmaceutique contenant diverses formes et souches de cannabis Download PDF

Info

Publication number
WO2019046661A1
WO2019046661A1 PCT/US2018/048982 US2018048982W WO2019046661A1 WO 2019046661 A1 WO2019046661 A1 WO 2019046661A1 US 2018048982 W US2018048982 W US 2018048982W WO 2019046661 A1 WO2019046661 A1 WO 2019046661A1
Authority
WO
WIPO (PCT)
Prior art keywords
cannabis
kief
strain
mash compound
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2018/048982
Other languages
English (en)
Inventor
Charles Jefferson MILLER
Danen KIRK CHRISTOPHER THIBODEAU
Bill James PLIFKA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Edivape International LLC
Original Assignee
Edivape International LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Edivape International LLC filed Critical Edivape International LLC
Publication of WO2019046661A1 publication Critical patent/WO2019046661A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/348—Cannabaceae
    • A61K36/3482—Cannabis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Definitions

  • the present invention relates to edible and smokable forms of cannabis and more particularly a process for combing multiple forms and strains of cannabis into a single composition that may be smoked and/or digested by eating, thereby allowing a user to receive the benefit of multiple strains of cannabis from a single dose.
  • Cannabis has long been used for medicinal purposes and recreational purposes.
  • Cannabis strains may be either pure or hybrid varieties of the Cannabis genus of plants, which include the species C. sativa and C. indica.
  • strains While both strains share the same cannabinoids, they vary in levels of THC, CBD, and Terpenes that classify them as Sativa or Indica.
  • Sativa' s cannabinoid profile is dominated by high THC levels and low or no CBD levels.
  • Indica's chemical profile shows a more balanced mix, with moderate THC levels and higher levels of CBD.
  • Indica strains relax muscles and work as general analgesics, also helping with sleep. A cancer patient hoping to relieve the pain from chemotherapy may benefit from the effects of an Indica plant.
  • Sativa strains produce more of a euphoric high, lifting the consumer's mood and therapeutically relieving stress, indicating Sativas may be useful at relieving anxiety and depression.
  • Varieties are developed to intensity specific characteristics of the plant, or to differentiate the strain for the purposes of marketing or to make it more effective as a drug.
  • Established strains offer many qualities that very from one strain to the next. Many of these qualities would be beneficial to users if a process was available wherein the strains were able to be combined in a consistent manner.
  • the primary object of the present invention is to provide a process wherein a plurality of cannabis strains may be combined in a consistent manner.
  • the present invention is a pharmaceutical composition of ground cannabis flour, cannabis oil and cannabis kief wherein a process forming the composition allows for a variety of blends to be created into a single end product.
  • the strain or strains of cannabis used to form the composition may be taken from a plurality of cannabis strains, thus making a compound of flowers which is finely ground and separated from cannabis kief.
  • cannabis oil is warmed to a low temperature until the cannabis oil is thin enough to stir.
  • the ground cannabis flour and cannabis oil are blended into an even consistency, thereby creating a mash compound.
  • the mash compound is then warmed in a humid oven until an even saturation is achieved.
  • the mash compound is cooled to room temperature.
  • the mash compound may then be separated into desired sizes and weights. After the mash compound is separated into desired doses, it may be molded into shapes. The outer surface of the molded mash compound is then covered with cannabis kief.
  • the present invention is a pharmaceutical composition of cannabis flour, cannabis oil and cannabis kief wherein a process forming the composition allows for a variety of blends to be created into a single end product.
  • the strains of cannabis used to form the composition may be taken from a plurality of cannabis strains, thus making a compound of flowers which is finely ground and separated from cannabis kief.
  • cannabis oil is warmed to a low temperature until the cannabis oil is thin enough to stir.
  • the ground cannabis flour and cannabis oil are blended into an even consistency, thereby creating a mash compound.
  • the mash compound is then warmed in a humid oven until an even saturation is achieved. Then the mash compound is cooled to room temperature.
  • the mash compound may then be separated into desired sizes and weights. After the mash compound is separated into desired doses, it may be molded into shapes. The outer surface of the molded mash compound is then covered with kief.
  • the resulting composition comprises the mash compound having formed as described above using at least one flour produced from a first strain of cannabis mixed with at least one oil produced from a second strain of cannabis.
  • the resulting mash compound is a formable compound that is then separated into individual doses and each dose is formed into a geometric shape, such as a ball, cube and so forth, or other equivalent shapes.
  • the formed shapes are then coated in at least one layer of cannabis kief dust produced from a third strain of cannabis.
  • the following examples illustrate various resulting embodiments of the composition of the present invention being made using the process of the present invention to combine various strains of cannabis.
  • the cannabis oil used to form the mash compound of the present invention and the resulting composition is preferably derived from a different strain of cannabis from which the cannabis flour and the cannabis kief are derived from.
  • Said cannabis kief may be substituted by a cannabis shatter, cannabis crystalline or equivalent cannabis product that will form an outer coating on the formed mash compound.
  • the ingredients are chosen from a Cannabis Strain A, Cannabis Strain B and Cannabis Strain C, each of which has one or more unique properties different from that of the other strains being used:
  • Cannabis Flour Cannabis Strain A
  • Cannabis Oil Cannabis Strain B
  • Cannabis Kief Cannabis Strain C EXAMPLE 2
  • Cannabis Flour Cannabis Strain B
  • Cannabis Oil Cannabis Strain A
  • Cannabis Kief Cannabis Strain C
  • Cannabis Flour Cannabis Strain C
  • Cannabis Oil Cannabis Strain A
  • Cannabis Kief Cannabis Strain B
  • Cannabis Flour Cannabis Strain C
  • Cannabis Oil Cannabis Strain B
  • Cannabis Kief Cannabis Strain A
  • the process of the present invention allows a consistent rotation of alternating strains of cannabis which are all combined into a single composition wherein accurate dosing may be achieved.
  • the cannabis oil, cannabis flour and the cannabis kief may all be derived from the same strain of cannabis and formed into the unique structure of the present invention using the process of the present invention as follows: EXAMPLE 5
  • Cannabis Flour Cannabis Strain A
  • Cannabis Oil Cannabis Strain A
  • Cannabis Kief Cannabis Strain A

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne un procédé dans lequel il est possible de combiner plusieurs souches de cannabis en une seule dose de cannabis. La composition résultante est une combinaison combinant avec précision diverses souches de cannabis et les bénéfices souhaités de chacune de ces souches. La composition résultante peut être façonnée sous diverses formes, ce qui la rend facile à administrer sous forme orale, ou sous une forme pour être fumée ou vapotée.
PCT/US2018/048982 2017-09-01 2018-08-30 Composition pharmaceutique contenant diverses formes et souches de cannabis Ceased WO2019046661A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201715694220A 2017-09-01 2017-09-01
US15/694,220 2017-09-01

Publications (1)

Publication Number Publication Date
WO2019046661A1 true WO2019046661A1 (fr) 2019-03-07

Family

ID=65526104

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2018/048982 Ceased WO2019046661A1 (fr) 2017-09-01 2018-08-30 Composition pharmaceutique contenant diverses formes et souches de cannabis

Country Status (1)

Country Link
WO (1) WO2019046661A1 (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016084075A1 (fr) * 2014-11-26 2016-06-02 One World Cannabis Ltd Utilisation synergique de cannabis pour le traitement d'un myélome multiple
US20170226077A1 (en) * 2016-02-09 2017-08-10 Robin James Bach Production of 11-Hydroxy-THC

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016084075A1 (fr) * 2014-11-26 2016-06-02 One World Cannabis Ltd Utilisation synergique de cannabis pour le traitement d'un myélome multiple
US20170226077A1 (en) * 2016-02-09 2017-08-10 Robin James Bach Production of 11-Hydroxy-THC

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
"What is kief and how can you use it?", LEAFLY, 15 October 2014 (2014-10-15), Retrieved from the Internet <URL:www.leafly.com/news/cannabis-101/what-is-kief> *
RABER J. C. ET AL.: "Understanding dabs: contamination concerns of cannabis concentrates and cannabinoid transfer during the act of dabbing", THE JOURNAL OF TOXICOLOGICAL SCIENCES, 2015, pages 797 - 803, XP055579838 *

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