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WO2018186770A8 - Специфические пептидные ингибиторы клатрина - Google Patents

Специфические пептидные ингибиторы клатрина Download PDF

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Publication number
WO2018186770A8
WO2018186770A8 PCT/RU2018/000121 RU2018000121W WO2018186770A8 WO 2018186770 A8 WO2018186770 A8 WO 2018186770A8 RU 2018000121 W RU2018000121 W RU 2018000121W WO 2018186770 A8 WO2018186770 A8 WO 2018186770A8
Authority
WO
WIPO (PCT)
Prior art keywords
peptides
clathrin inhibitors
inhibitors
specific peptide
proposed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/RU2018/000121
Other languages
English (en)
French (fr)
Other versions
WO2018186770A1 (ru
Inventor
Олег Аркадьевич КОТИН
Аркадий Михайлович КОТИН
Максим Олегович ЕМЕЛЬЯНОВ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CA3058388A priority Critical patent/CA3058388A1/en
Priority to EP18781670.7A priority patent/EP3741382A4/en
Priority to US16/500,592 priority patent/US20220088113A1/en
Priority to CN201880023947.0A priority patent/CN110869043A/zh
Priority to JP2019554629A priority patent/JP2020512996A/ja
Publication of WO2018186770A1 publication Critical patent/WO2018186770A1/ru
Anticipated expiration legal-status Critical
Publication of WO2018186770A8 publication Critical patent/WO2018186770A8/ru
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Изобретение относится к химико-фармацевтической промышленности. Предложено применение синтетических пептидов в качестве специфических ингибиторов клатрина. Предложен также способ профилактики или лечения заболевания или состояния у животного, включающий введение эффективного количества пептидов или пролекарства или физиологически приемлемой соли или сольвата вышеназванных пептидов, или фармацевтической композиции, содержащей вышеназванные пептиды, как специфических ингибиторов клатрина. Пептиды могут найти применение в медицине, ветеринарии и фармакологии для создания новых лекарственных средств, являющихся специфическими ингибиторами клатрина.
PCT/RU2018/000121 2017-04-07 2018-03-01 Специфические пептидные ингибиторы клатрина Ceased WO2018186770A1 (ru)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA3058388A CA3058388A1 (en) 2017-04-07 2018-03-01 Specific peptide clathrin inhibitors
EP18781670.7A EP3741382A4 (en) 2017-04-07 2018-03-01 SPECIFIC PEPTIDE CLATHRIN INHIBITORS
US16/500,592 US20220088113A1 (en) 2017-04-07 2018-03-01 Specific peptide clathrin inhibitors
CN201880023947.0A CN110869043A (zh) 2017-04-07 2018-03-01 特异性肽网格蛋白抑制剂
JP2019554629A JP2020512996A (ja) 2017-04-07 2018-03-01 クラスリンの特異的ペプチド阻害剤

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2017111896 2017-04-07
RU2017111896A RU2651491C1 (ru) 2017-04-07 2017-04-07 Специфические пептидные ингибиторы клатрина

Publications (2)

Publication Number Publication Date
WO2018186770A1 WO2018186770A1 (ru) 2018-10-11
WO2018186770A8 true WO2018186770A8 (ru) 2019-10-24

Family

ID=61976775

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/RU2018/000121 Ceased WO2018186770A1 (ru) 2017-04-07 2018-03-01 Специфические пептидные ингибиторы клатрина

Country Status (7)

Country Link
US (1) US20220088113A1 (ru)
EP (1) EP3741382A4 (ru)
JP (1) JP2020512996A (ru)
CN (1) CN110869043A (ru)
CA (1) CA3058388A1 (ru)
RU (1) RU2651491C1 (ru)
WO (1) WO2018186770A1 (ru)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1306976A (zh) * 2000-01-26 2001-08-08 上海博道基因技术有限公司 一种新的多肽——网格蛋白76和编码这种多肽的多核苷酸
JP2009250552A (ja) 2008-04-08 2009-10-29 Kyoritsu Air Tech Inc 換気グリル
JP5493714B2 (ja) 2009-10-30 2014-05-14 国立大学法人信州大学 クラスリン結合性ペプチド誘導体
WO2011088431A1 (en) * 2010-01-18 2011-07-21 Vela Eric M Prophylactic and treatment for virus-induced disease
WO2013010218A1 (en) * 2011-07-15 2013-01-24 Freie Universität Berlin Inhibition of clathrin
RU2508295C2 (ru) * 2012-03-22 2014-02-27 Общество с ограниченной ответственностью "Биофармокс" Синтетические пептиды с ненаркотическим типом анальгетического действия

Also Published As

Publication number Publication date
RU2651491C1 (ru) 2018-04-19
US20220088113A1 (en) 2022-03-24
CN110869043A (zh) 2020-03-06
WO2018186770A1 (ru) 2018-10-11
EP3741382A1 (en) 2020-11-25
JP2020512996A (ja) 2020-04-30
EP3741382A4 (en) 2021-04-28
CA3058388A1 (en) 2018-10-11

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