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WO2018186611A3 - Bioencre et son procédé de préparation - Google Patents

Bioencre et son procédé de préparation Download PDF

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Publication number
WO2018186611A3
WO2018186611A3 PCT/KR2018/003353 KR2018003353W WO2018186611A3 WO 2018186611 A3 WO2018186611 A3 WO 2018186611A3 KR 2018003353 W KR2018003353 W KR 2018003353W WO 2018186611 A3 WO2018186611 A3 WO 2018186611A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
bioink
method therefor
prepared
mechanical properties
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2018/003353
Other languages
English (en)
Korean (ko)
Other versions
WO2018186611A2 (fr
Inventor
박찬흠
김순희
이정민
연응규
이영진
서예빈
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Industry Academic Cooperation Foundation of Hallym University
Original Assignee
Industry Academic Cooperation Foundation of Hallym University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Industry Academic Cooperation Foundation of Hallym University filed Critical Industry Academic Cooperation Foundation of Hallym University
Publication of WO2018186611A2 publication Critical patent/WO2018186611A2/fr
Publication of WO2018186611A3 publication Critical patent/WO2018186611A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D11/00—Inks
    • C09D11/02—Printing inks
    • C09D11/03—Printing inks characterised by features other than the chemical nature of the binder
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D11/00—Inks
    • C09D11/02—Printing inks
    • C09D11/10—Printing inks based on artificial resins
    • C09D11/106—Printing inks based on artificial resins containing macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D133/00—Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Coating compositions based on derivatives of such polymers
    • C09D133/04—Homopolymers or copolymers of esters
    • C09D133/06—Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, the oxygen atom being present only as part of the carboxyl radical
    • C09D133/10—Homopolymers or copolymers of methacrylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials For Medical Uses (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Macromonomer-Based Addition Polymer (AREA)

Abstract

La présente invention concerne une bioencre qui est préparée à partir de fibroïne de soie, une fibre de protéine naturelle, et à partir de laquelle des tissus biologiques ayant une cytocompatibilité améliorée et des propriétés mécaniques exceptionnelles peuvent être préparés à l'aide d'une imprimante 3D, et un procédé de préparation associé. Par impression 3D, la présente invention peut préparer un tissu biologique ayant des propriétés mécaniques telles que le pouvoir absorbant d'humidité, le taux d'expansion de volume, la résistance à la compression, la résistance à la traction, etc. De plus, la préparation d'une bioencre comprenant de la fibroïne de soie en tant que squelette de base permet la construction d'une biostructure qui ne provoque pratiquement aucune réponse immunitaire dans le corps et a donc une excellente biocompatibilité.
PCT/KR2018/003353 2017-04-04 2018-03-22 Bioencre et son procédé de préparation Ceased WO2018186611A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2017-0043518 2017-04-04
KR1020170043518A KR101983741B1 (ko) 2017-04-04 2017-04-04 바이오 잉크 및 이의 제조방법

Publications (2)

Publication Number Publication Date
WO2018186611A2 WO2018186611A2 (fr) 2018-10-11
WO2018186611A3 true WO2018186611A3 (fr) 2019-01-10

Family

ID=63712162

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2018/003353 Ceased WO2018186611A2 (fr) 2017-04-04 2018-03-22 Bioencre et son procédé de préparation

Country Status (2)

Country Link
KR (1) KR101983741B1 (fr)
WO (1) WO2018186611A2 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102124579B1 (ko) 2018-12-04 2020-06-18 한국생산기술연구원 세포 괴사를 최소화하는 바이오잉크 조성물 및 이를 이용한 생체구조체의 제조방법
KR102188574B1 (ko) 2019-03-12 2020-12-08 울산과학기술원 바이오 프린팅용 잉크 조성물 및 그로부터 형성된 하이드로젤
KR102211477B1 (ko) * 2019-08-30 2021-02-03 충남대학교산학협력단 3d 바이오프린팅용 바이오잉크 및 그의 제조방법
KR102180865B1 (ko) 2019-09-30 2020-11-19 한림대학교 산학협력단 전기전도성을 갖는 광가교 바이오 잉크 조성물 및 이의 제조방법
CN111454614B (zh) * 2020-05-28 2022-05-24 苏州大学 3d生物打印墨水及其制备方法和应用
CN113956506B (zh) * 2020-07-03 2023-07-21 中国科学院苏州纳米技术与纳米仿生研究所 一种双网络水凝胶及其制备方法与应用
CN112111072A (zh) * 2020-09-17 2020-12-22 南京工业大学 可3D打印的ε-聚赖氨酸抗菌水凝胶及其制备方法与应用
KR102462953B1 (ko) * 2020-12-03 2022-11-02 아주대학교산학협력단 바이오 프린팅용 광가교 히알루론산 바이오잉크, 이의 제조방법 및 이를 이용한 물성 조절이 가능한 생체구조체
CN112516330B (zh) * 2020-12-15 2023-08-04 上海交通大学医学院附属第九人民医院 丝素蛋白与甲状旁腺激素偶联接枝的方法及其应用
KR102415399B1 (ko) 2021-03-24 2022-07-01 한림대학교 산학협력단 다중 세포 및 재료의 프린팅이 가능한, 마그네틱 체결 수조가 포함된 바이오 DLP(digital lighting processing) 3D 프린터
CN113713179B (zh) * 2021-09-06 2022-08-02 山东大学 高综合性能光固化生物3d打印复合水凝胶及其制备方法和应用
KR102841005B1 (ko) 2022-07-22 2025-08-01 한림대학교 산학협력단 재생 의학용 초강력 전기전도성 생체 적합 하이드로겔 제조용 광경화성 바이오 잉크 및 이의 제조 방법
WO2024144269A1 (fr) * 2022-12-27 2024-07-04 한국재료연구원 Bio-encre comprenant un peptide fonctionnel
KR20240167117A (ko) 2023-05-19 2024-11-26 한림대학교 산학협력단 형광 바이오잉크의 제조방법 및 이에 따라 제조된 형광 실크 피브로인을 포함하는 바이오잉크
CN116726247B (zh) * 2023-06-15 2025-10-28 浙江大学 一种3d打印强韧丝素蛋白支架材料的制备方法和应用
CN116925396A (zh) * 2023-07-19 2023-10-24 西湖大学 丝蛋白基墨水及其用于3d打印制备组织工程支架的应用
KR20250093878A (ko) 2023-12-18 2025-06-25 국립순천대학교산학협력단 3d 바이오프린팅을 위한 실크 피브로인 기반 감열성 바이오잉크

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3005667B2 (ja) * 1996-11-06 2000-01-31 農林水産省蚕糸・昆虫農業技術研究所長 改変絹タンパク質、その製造方法および骨結合性材料
KR20110012204A (ko) * 2009-07-30 2011-02-09 (주)라이브에이비씨 지리적 연상작용을 이용한 어학 서비스 제공 방법 및 그 시스템
US20150376248A1 (en) * 2013-02-06 2015-12-31 Virginia Commonwealth University Photoactive silk protein and fabrication of silk protein structures using photolithography
KR20170001444A (ko) * 2015-06-26 2017-01-04 아주대학교산학협력단 바이오 잉크의 제조방법 및 3d 프린터 적용

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US8153591B2 (en) 2003-08-26 2012-04-10 Gel-Del Technologies, Inc. Protein biomaterials and biocoacervates and methods of making and using thereof
KR101176793B1 (ko) * 2010-05-03 2012-09-07 대한민국(농촌진흥청장) 실크 피브로인 가수분해물과 ｐｍｍａ를 함유하는 생체적합성 골 시멘트 조성물

Patent Citations (4)

* Cited by examiner, † Cited by third party
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JP3005667B2 (ja) * 1996-11-06 2000-01-31 農林水産省蚕糸・昆虫農業技術研究所長 改変絹タンパク質、その製造方法および骨結合性材料
KR20110012204A (ko) * 2009-07-30 2011-02-09 (주)라이브에이비씨 지리적 연상작용을 이용한 어학 서비스 제공 방법 및 그 시스템
US20150376248A1 (en) * 2013-02-06 2015-12-31 Virginia Commonwealth University Photoactive silk protein and fabrication of silk protein structures using photolithography
KR20170001444A (ko) * 2015-06-26 2017-01-04 아주대학교산학협력단 바이오 잉크의 제조방법 및 3d 프린터 적용

Non-Patent Citations (2)

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Title
FURUZONO, T. ET AL.: "Chemical Modificaiton of Silk Fibroin with 2-meihyacryloyl Oxyethyl Phosphorylcholine. II. Graft-polymerization onto Fabric through 2-methyacryloyloxyethyl Isocyanate and Interaction between Fabric and Platelets", BIOMATERIALS, vol. 21, no. 4, 2000, pages 327 - 333, XP004184114 *
KUNDU, JOYDIP ET AL.: "Silk Fibroin/poly(vinyl alcohol) Photocrosslinked Hydrogels for Delivery of Macromolecular Drugs", ACTA BIOMATERIALIA, vol. 8, no. 5, 2012, pages 1720 - 1729, XP028476144 *

Also Published As

Publication number Publication date
KR101983741B1 (ko) 2019-09-10
WO2018186611A2 (fr) 2018-10-11
KR20180112436A (ko) 2018-10-12

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