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WO2018072665A1 - 一种多腔式雾化设备 - Google Patents

一种多腔式雾化设备 Download PDF

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Publication number
WO2018072665A1
WO2018072665A1 PCT/CN2017/106286 CN2017106286W WO2018072665A1 WO 2018072665 A1 WO2018072665 A1 WO 2018072665A1 CN 2017106286 W CN2017106286 W CN 2017106286W WO 2018072665 A1 WO2018072665 A1 WO 2018072665A1
Authority
WO
WIPO (PCT)
Prior art keywords
drug storage
cavity
bottle body
storage bottle
chamber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2017/106286
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English (en)
French (fr)
Inventor
曹立
林洪涛
徐义全
黄芳芳
李建霖
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sunshine Lake Pharma Co Ltd
Original Assignee
Sunshine Lake Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sunshine Lake Pharma Co Ltd filed Critical Sunshine Lake Pharma Co Ltd
Priority to CN201780006885.8A priority Critical patent/CN108463261A/zh
Publication of WO2018072665A1 publication Critical patent/WO2018072665A1/zh
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes

Definitions

  • the invention relates to the technical field of medical instruments, and in particular to a multi-chamber atomization device.
  • the medical device includes a product which is an atomizer.
  • the atomizer is mainly used for treating various upper and lower respiratory diseases, such as cold, fever, cough, asthma, sore throat, pharyngitis, rhinitis, bronchitis, pneumoconiosis, etc. Diseases occurring in the bronchi, alveoli, and thoracic cavity.
  • Nebulized inhalation therapy is an important and effective treatment method for the treatment of respiratory diseases.
  • the nebulizer is used to atomize the liquid into tiny particles. The drug enters the respiratory tract and lungs by breathing inhalation, thereby achieving painlessness. The purpose of rapid and effective treatment.
  • the drug storage devices of the atomizer are single-chamber type, and in actual use, some drugs have poor stability, and the active ingredient of the drug needs to be separated from the solution during storage, and the drug is only used when used. Mix with the solution to ensure the best effect of the agent.
  • a drug storage device capable of separating a drug from a solution is not provided, and for a drug having poor stability, there is a risk of a decrease in efficacy or even failure.
  • the object of the present invention is to provide a multi-chamber atomization device which can effectively form a medicament before use.
  • the solution is separated from the solution and mixed only when it is used, thereby improving the effect of the agent.
  • a multi-chamber atomization device comprising a multi-chamber drug storage device for storing a medicament, the multi-chamber drug storage device comprising a drug storage bottle body, the inner cavity of the drug storage bottle body being provided with a spacer
  • the spacer divides the inner cavity of the drug storage bottle body into at least two cavityes, and the different cavityes are separated from each other before the drug is used. When the medicine is used, different the cavityes are mutually connected. Turn on.
  • the isolation function will be broken to make the different cavities conduct, so that the active ingredient of the medicament is separated from the solution before use, and the external pressure can be mixed when used.
  • the effect is to improve the effect of the medicament.
  • the number of the spacers and the cavity is arbitrarily selected and designed according to the kind of the drug.
  • the drug storage bottle body is made of a plastic deformation material
  • the separator includes a first sealing film, and the first sealing film is fixedly connected to an inner wall of the drug storage bottle body.
  • the first sealing film divides the inner cavity of the drug storage bottle body into a first cavity and a second cavity.
  • the first sealing film is a flexible sealing film, and the first sealing film is easily broken under external force. Specifically, an external force is applied to the sidewall of the drug storage bottle body to force deformation of the drug storage bottle body, thereby rupturing the first sealing film, and the first cavity and the second The cavity is turned on.
  • the first sealing film is disposed between the bottle mouth of the drug storage bottle body and the bottom of the bottle.
  • the spacer further includes a second sealing film, the second sealing film is located between the first sealing film and the bottom of the drug storage bottle body, the second sealing The membrane is fixedly attached to the inner wall of the reservoir body.
  • the first sealing film and the second sealing film divide the inner cavity of the drug storage bottle body into a first cavity, a second cavity and a third cavity.
  • the second sealing film is a flexible sealing film, and the second sealing film is easily broken under external force. Specifically, an external force is applied to the side wall of the drug storage bottle body to force deformation of the drug storage bottle body, thereby breaking the first sealing film and the second sealing film to make the first cavity
  • the second cavity is electrically connected to the third cavity.
  • the spacer further comprises a third sealing film, the third sealing film being located between the second sealing film and the bottom of the drug storage bottle body, the third sealing film and the storage
  • the inner wall of the vial body is fixedly connected, and the third sealing film is a flexible sealing film.
  • the first sealing film, the second sealing film and the third sealing film divide the inner cavity of the drug storage bottle body into a first cavity, a second cavity, a third cavity and a fourth cavity.
  • the number of sealing films and cavities can be selected according to the number of drugs to be mixed to satisfy the storage of a plurality of different drugs.
  • the drug storage bottle body is made of a rigid material
  • the separator comprises a first partition plate, and the first partition plate is slidably connected to an inner wall of the drug storage bottle body,
  • the inner cavity of the drug storage bottle body is outwardly extended with at least one first convex cavity, the width of the first convex cavity is larger than the thickness of the first partition, and the inner cavity of the drug storage bottle body
  • a rear partition plate is disposed on a side of the separating member away from the bottle mouth of the drug storage bottle body, the rear partition plate is slidably connected to an inner wall of the drug storage bottle body, and the thickness of the rear partition plate is The sum of the thicknesses of the first partitions is greater than the width of the first raised pockets.
  • the first partition partitions the inner cavity of the drug storage bottle body into a first cavity and a second cavity.
  • the first partition is located at a side of the first convex cavity away from the mouth of the drug storage bottle body.
  • an external force is applied to the rear partition to drive the rear partition to move toward the first partition, and when the medicament in the second chamber is compressed to a certain extent, the rear The baffle will drive the first baffle to move toward the first convex cavity by the compressed medicament until the first baffle reaches the position of the first convex cavity due to the a raised cavity
  • the width of the first partition is larger than the thickness of the first partition, so that the first convex cavity forms a conduction interval on both sides of the first partition, so that the first cavity and the second volume
  • the cavity is turned on, at which time the pressure in the second cavity is released, and the first spacer is not continuously driven to move, so that the first spacer stays at the position of the first convex cavity, thereby
  • the first cavity and the second cavity are kept in an on state, and finally the rear baffle is adhered to the first baffle, and an external force is
  • the multi-chamber drug storage device is gently shaken to uniformly mix the medicaments, and then the multi-chamber drug storage device is connected to the atomization device to perform atomization treatment.
  • the width of the first convex cavity refers to the dimension of the first convex cavity along the line connecting the mouth of the drug storage bottle body and the bottom of the bottle;
  • the thickness refers to the dimension of the first partition along the line connecting the mouth of the drug storage bottle body to the bottom of the bottle.
  • the spacer further includes a second partition, the second partition is located between the first partition and the rear partition, and the second partition is The inner wall of the drug storage bottle body is slidably connected, and the inner cavity of the drug storage bottle body is outwardly extended with at least one second convex cavity, and the width of the second convex cavity is larger than that of the second partition a thickness, the second convex cavity is located between the first convex cavity and the rear partition, and a sum of a thickness of the rear partition and a thickness of the second partition is greater than the first The width of the two raised pockets.
  • the first partition and the second partition divide the inner cavity of the drug storage bottle body into a first cavity, a second cavity and a third cavity.
  • the second partition is located on a side of the second convex cavity away from the mouth of the drug storage bottle body.
  • the width of the first convex cavity refers to the dimension of the first convex cavity along the line connecting the mouth of the drug storage bottle body and the bottom of the bottle;
  • the thickness refers to the dimension of the first partition along the line connecting the mouth of the drug storage bottle body to the bottom of the bottle.
  • the width of the first convex cavity is equal to the width of the second convex cavity
  • the thickness of the first partition is equal to the thickness of the second partition
  • a plurality of the first convex cavities are equally spaced along the circumferential direction of the drug storage bottle body, and all of the first convex cavity and the bottle mouth of the drug storage bottle body The distance between the two raised cavities is equally spaced along the circumferential direction of the drug storage bottle body, and all of the second convex cavity is between the bottle mouth of the drug storage bottle body The distance between the second convex cavity and the mouth of the drug storage bottle body is greater than the distance between the first convex cavity and the bottle mouth of the drug storage bottle body.
  • the number of the first convex cavities is 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 or 9 or 10.
  • the number of the second convex cavities is 1 or 2 or 3 or 4 or 5 or 6 or 7 or 8 or 9 or 10.
  • the number of the first convex cavity is equal to the number of the second convex cavity.
  • providing a plurality of the first convex cavity and the second convex cavity can increase a conduction area between different cavities, thereby improving mixing efficiency.
  • the invention further includes an atomizing sheet mounted on one end of the flow guiding joint, and an inclined flow channel on the guiding joint, the inclined flow channel Communicating with the atomizing sheet, the multi-chamber drug storage device is mounted on a side of the inclined flow path away from the atomizing sheet, and the inclined flow channel is adjacent to an end of the atomizing sheet One end of the multi-chamber drug storage device is tilted upward.
  • the total residual amount of the liquid medicine below the liquid level calibration line for the normal operation of the atomizing sheet comprises two parts, the first part is the residual amount in the inclined flow channel, and the second part is that the flow guiding joint is away from the liquid storage container The amount of residue in the mounting groove at one end.
  • the residual amount of the first portion decreases as the inclination angle of the inclined flow channel increases. Therefore, the solution connects the atomization sheet and the liquid storage container through the flow guiding joint, and opens the inclined flow channel on the flow guiding joint, and tilts
  • the designed inclined flow channel can reduce the liquid storage space below the normal working liquid level of the atomizing piece, effectively reducing the volume of the liquid medicine remaining in the atomizer which cannot be atomized, thereby reducing waste.
  • a horizontal flow channel may be formed on the flow guiding joint, the horizontal flow channel is in communication with the atomizing sheet, and the multi-chamber drug storage device is installed on the horizontal flow channel away from the atomizing sheet.
  • One side. The axis of the horizontal flow path is parallel to the horizontal plane.
  • the angle between the axial line of the inclined flow channel and the horizontal plane is 10 degrees or more and 70 degrees or less.
  • the angle between the axial line of the inclined flow channel and the horizontal plane is 15 degrees or more and 60 degrees or less.
  • the angle between the axis of the inclined flow channel and the horizontal plane is 10 degrees or 15 degrees or 20 degrees or 25 degrees or 30 degrees or 35 degrees or 40 degrees or 45 degrees or 50 degrees or 55 degrees or 60 degrees or 65 degrees or 70 degrees.
  • the shape of the port on the side of the inclined flow path adjacent to the atomizing sheet is elliptical, and in the case where the length of the long axis of the port on the side of the inclined flow path close to the atomizing sheet is fixed, As the inclination angle of the inclined flow path increases, the diameter of the inclined flow path will decrease. Due to the surface tension of the liquid, the liquid does not easily pass through a narrow space under the action of its own gravity, that is, the smaller the diameter of the inclined flow path, the more difficult the liquid medicine passes through the inclined flow path, and thus the diameter of the inclined flow path Can not be too small, so that the liquid can not pass smoothly. According to the above analysis, the inclination angle of the inclined flow channel cannot be too Large, otherwise it will cause the liquid medicine to pass through the inclined flow channel to cause insufficient supply of liquid medicine.
  • the inclined flow path is disposed at one end of the atomizing sheet from the container interface, and the bottle mouth position of the multi-chamber drug storage device is provided with a container joint, and the container joint is inserted in Inside the container interface.
  • the axis line of the container interface is on the same line as the axis line of the inclined flow channel;
  • the axis of the container interface is parallel to the horizontal plane
  • the axis of the container interface is perpendicular to the horizontal plane.
  • the multi-chamber drug storage device is detachably connected to the flow guiding joint.
  • a housing is further included, and the flow guiding joint is detachably connected to the housing.
  • the invention has the beneficial effects of providing a multi-chamber atomization device, which is divided into at least two cavities by providing a spacer in the inner cavity of the drug storage bottle body. After the spacer is subjected to external pressure, the isolation function will be broken and the different chambers will be turned on, so that the active ingredient of the medicament is separated from the solution before use, and the external pressure can be mixed during use to improve the medicament. The effect of the effect.
  • FIG. 1 is a schematic cross-sectional view of the multi-chamber drug storage device of the first embodiment
  • FIG. 2 is a schematic structural view of an atomizing device according to an embodiment
  • Figure 3 is an exploded view of the atomizing device of the embodiment
  • FIG. 5 is a cross-sectional view showing a flow guiding joint, a multi-chamber drug storage device, and a rectifying ring according to an embodiment
  • FIG. 6 is a cross-sectional view showing the multi-chamber drug storage device of the second embodiment
  • Figure 7 is a cross-sectional view showing a state of the multi-chamber drug storage device of the fourth embodiment
  • Figure 8 is a cross-sectional view showing another state of the multi-chamber drug storage device of the fourth embodiment.
  • Figure 9 is a cross-sectional view showing still another state of the multi-chamber drug storage device of the fourth embodiment.
  • Figure 10 is a cross-sectional view showing the multi-chamber drug storage device of the fifth embodiment.
  • FIG. 11 is a schematic structural view of an atomizing device according to Embodiment 8.
  • Figure 12 is a cross-sectional view showing the multi-chamber drug storage device of the eighth embodiment.
  • Multi-chamber storage device 1. Multi-chamber storage device
  • Embodiment 1 is a diagrammatic representation of Embodiment 1:
  • a multi-chamber atomization device includes a multi-chamber drug storage device 1.
  • the multi-chamber drug storage device 1 includes a drug storage bottle body 101, and the inner cavity of the drug storage bottle body 101 is provided with a spacer separating the inner cavity of the drug storage bottle body 101 into two chambers, and different chambers are separated from each other before use of the medicine, and the different chambers are used when the medicine is used. They are mutually conductive. Specifically, after the spacer is subjected to external pressure, the isolation function will be broken to make the different cavities conduct, so that the active ingredient of the medicament is separated from the solution before use, and the external pressure can be mixed when used. The effect is to improve the effect of the medicament.
  • the drug storage bottle body 101 is made of a plastic deformation material
  • the separator includes a first sealing film 108
  • the first sealing film 108 is fixedly connected to the inner wall of the drug storage bottle body 101.
  • the first sealing film 108 is disposed between the bottle mouth 102 of the drug storage bottle body 101 and the bottle bottom 103, and the first sealing film 108 separates the inner cavity of the drug storage bottle body 101 into the first The cavity 105 and the second cavity 106.
  • the first sealing film 108 is a flexible sealing film, and the first sealing film 108 is easily broken under an external force. Specifically, an external force is applied to the side wall of the drug storage bottle body 101 to force the deformation of the drug storage bottle body 101, thereby rupturing the first sealing film 108, so that the first cavity 105 is The second cavity 106 is electrically connected.
  • the multi-chamber atomization device further includes an atomizing sheet 2 and a flow guiding joint 3, and the atomizing sheet 2 is mounted at one end of the flow guiding joint 3, and the flow guiding joint 3 is provided with an inclined flow channel 31 communicating with the atomizing sheet 2, and the multi-chamber drug storage device 1 is mounted on the inclined flow channel 31 away from the atomizing sheet 2
  • the inclined flow path 31 is inclined upward toward an end close to the multi-chamber drug storage device 1 along an end close to the atomizing sheet 2.
  • the angle between the axis of the inclined flow path 31 and the horizontal plane is 10 degrees.
  • the total residual amount of the liquid medicine below the liquid level calibration line for the normal operation of the atomizing sheet 2 includes two parts, the first part is the residual amount in the inclined flow channel 31, and the second part is the flow guiding joint 3 away from the The residual amount in the mounting groove at one end of the liquid storage container.
  • the residual amount of the first portion decreases as the inclination angle of the inclined flow passage 31 increases. Therefore, the present embodiment connects the atomization sheet 2 and the liquid storage container through the flow guiding joint 3, and the inclined portion is opened on the flow guiding joint 3.
  • the flow passage 31 and the inclined flow passage 31 of the inclined design can reduce the liquid storage space below the normal working liquid level of the atomizing sheet 2, effectively reducing the volume of the chemical liquid remaining in the atomizer which cannot be atomized, thereby reducing waste.
  • the inclined flow channel 31 is disposed away from the one end of the atomizing sheet 2 with a container interface 32.
  • the bottle opening 102 of the multi-chamber drug storage device 1 is disposed at a position of a container joint 104.
  • a joint 104 is inserted into the container interface 32.
  • the axis line of the container interface 32 is on the same line as the axis line of the inclined flow path 31. In other embodiments, the axis of the container interface is parallel to the horizontal plane; or the axis of the container interface is perpendicular to the horizontal plane.
  • the atomization device further includes a housing 4, the flow guiding joint 3 is detachably connected to the housing 4, and the multi-chamber drug storage device 1 and the flow guiding joint 3 Removable connection.
  • the atomization device further includes a rectifying ring 5 mounted at an end of the flow guiding joint 3 away from the multi-chamber drug storage device 1, the rectifying ring 5 and the The inclined flow path 31 holds the atomizing sheet 2.
  • the atomization device further includes an electronic control unit 6 mounted in the housing 4, and the electric control unit 6 and the guide unit 3 are mounted on the housing 4.
  • the atomizing sheet 2 is electrically connected.
  • the electronic control unit 6 includes a time control element and a voltage control element, and the time control element is electrically connected to the atomizing sheet 2 for controlling the working time of the atomizing sheet 2;
  • the atomizing sheet 2 is electrically connected for supplying an operating voltage to the atomizing sheet 2.
  • the atomization efficiency of the atomizing sheet 2 is solidified, and therefore, The operation of the atomizing sheet 2
  • the total amount of drug atomization achieved by the atomizing sheet 2 is fixed, and the total amount of atomization is equal to the product of the atomization efficiency and the working time. Therefore, by controlling the atomization efficiency and the working time, the program can control the total amount of atomization of the therapeutic drug and improve the accuracy of the patient's medication.
  • Embodiment 2 is a diagrammatic representation of Embodiment 1:
  • the spacer divides the inner cavity of the drug storage bottle body 101 into three cavities, and the spacer further includes a second sealing film 109, and the second sealing film 109 is located at the Between the first sealing film 108 and the bottom 103 of the drug storage bottle body 101, the second sealing film 109 is fixedly coupled to the inner wall of the drug storage bottle body 101, the first sealing film 108 and the The second sealing film 109 divides the inner cavity of the drug storage bottle body 101 into a first volume 105, a second volume 106, and a third volume 107.
  • the second sealing film 109 is a flexible sealing film, and the second sealing film 109 is easily broken under an external force.
  • an external force is applied to the side wall of the drug storage bottle body 101 to force the deformation of the drug storage bottle body 101, thereby rupturing the first sealing film 108 and the second sealing film 109, so that the The first cavity 105 and the second cavity 106 are electrically connected to the third cavity 107.
  • Embodiment 3 is a diagrammatic representation of Embodiment 3
  • the spacer divides the inner cavity of the drug storage bottle body into four cavities, the spacer further includes a third sealing film, and the third sealing film is located at the second sealing film and the drug storage
  • the third sealing film is fixedly connected to the inner wall of the drug storage bottle body between the bottle bottoms of the bottle body, and the third sealing film is a flexible sealing film.
  • the first sealing film, the second sealing film and the third sealing film divide the inner cavity of the drug storage bottle body into a first cavity, a second cavity, a third cavity and a fourth cavity.
  • the isolation The piece may also divide the inner cavity of the vial body into five or more cavities.
  • Embodiment 4 is a diagrammatic representation of Embodiment 4:
  • a multi-chamber atomization device comprising a multi-chamber drug storage device 1 , as shown in FIGS. 7 to 9 , the multi-chamber drug storage device 1 includes a drug storage bottle body 101 inside the drug storage bottle body 101
  • the cavity is provided with a spacer, and the spacer divides the inner cavity of the drug storage bottle body 101 into two cavityes. Before the drug is used, different cavityes are separated from each other, and when the medicine is used, different places are used.
  • the chambers are electrically connected to each other. Specifically, after the spacer is subjected to external pressure, the isolation function will be broken to make the different cavities conduct, so that the active ingredient of the medicament is separated from the solution before use, and the external pressure can be mixed when used. The effect is to improve the effect of the medicament.
  • the drug storage bottle body 101 is made of a rigid material, and the spacer includes a first partition plate 110, and the first partition plate 110 is slidably connected to an inner wall of the drug storage bottle body 101.
  • the inner cavity of the drug storage bottle body 101 is outwardly extended with a first convex cavity 111, and the width of the first convex cavity 111 is greater than the thickness of the first separator 110, and the drug storage
  • the inner cavity of the bottle body 101 and the side of the spacer away from the bottle opening 102 of the drug storage bottle body 101 are provided with a rear partition plate 114, and the rear partition plate 114 and the inner wall of the drug storage bottle body 101
  • the sliding connection, the sum of the thickness of the rear partition 114 and the thickness of the first partition 110 is greater than the width of the first convex cavity 111.
  • the width of the first convex cavity 111 refers to the dimension of the first convex cavity 111 along the line connecting the bottle mouth 102 of the drug storage bottle body 101 and the bottom 103;
  • the thickness of a partition plate 110 refers to the dimension of the first partition plate 110 along the line direction of the bottle opening 102 of the drug storage bottle body 101 and the bottom 103 of the bottle.
  • the first partition 110 divides the inner cavity of the drug storage bottle body 101 into a first cavity 105 and a second cavity 10G. Before the drug is used, the first partition 110 is located at a side of the first convex cavity 111 away from the bottle opening 102 of the drug storage bottle body 101. When in use, an external force is applied to the rear partition 114 to drive The rear partition 114 moves in a direction close to the first partition 110. When the medicament in the second chamber 10G is compressed to a certain extent, the rear partition 114 will drive through the compressed medicament.
  • the first partition plate 110 moves in the direction of the first convex cavity 111 until the first partition plate 110 reaches the position of the first convex cavity 111, due to the first convex cavity
  • the width of the first partition 110 is greater than the thickness of the first partition 110.
  • the first convex cavity 111 forms a conductive interval 115 on both sides of the first partition 110, so that the first cavity 105 is Conducting with the second cavity 10G, at which time the pressure in the second cavity 10G is released, and the first spacer 110 cannot be continuously driven to move, so that the first spacer 110 stays in the Positioning the first cavity 111 to maintain the first cavity 105 and the second cavity 10G in a conducting state, and finally bonding the rear partition 114 to the first partition 110 At this time, the application of an external force to the rear partition 114 is stopped.
  • the conduction gap 115 is closed, so that the medicament cannot be removed from the The rear partition 114 leaks, thereby avoiding waste of the medicament and ensuring hygiene of the medicament.
  • the multi-chamber atomization device further includes an atomizing sheet 2 and a flow guiding joint 3, and the atomizing sheet 2 is mounted at one end of the flow guiding joint 3, and the flow guiding joint 3 is provided with an inclined flow channel 31 communicating with the atomizing sheet 2, and the multi-chamber drug storage device 1 is mounted on the inclined flow channel 31 away from the atomizing sheet 2
  • the inclined flow path 31 is inclined upward toward an end close to the multi-chamber drug storage device 1 along an end close to the atomizing sheet 2.
  • the angle between the axis of the inclined flow path 31 and the horizontal plane is 70 degrees.
  • the angle between the axis of the inclined flow channel and the horizontal plane may also be 15 degrees or 20 degrees or 25 degrees or 30 degrees or 35 degrees or 40 degrees or 45 degrees or 50 degrees or 55. Degree or 60 degrees or 65 degrees.
  • the total residual amount of the liquid medicine below the liquid level calibration line of the atomizing sheet 2 working normally includes two parts.
  • the first portion is the residual amount in the inclined flow path 31, and the second portion is the residual amount of the flow guiding joint 3 in the mounting groove away from the end of the liquid storage container.
  • the residual amount of the first portion decreases as the inclination angle of the inclined flow passage 31 increases. Therefore, the present embodiment connects the atomization sheet 2 and the liquid storage container through the flow guiding joint 3, and the inclined portion is opened on the flow guiding joint 3.
  • the flow passage 31 and the inclined flow passage 31 of the inclined design can reduce the liquid storage space below the normal working liquid level of the atomizing sheet 2, effectively reducing the volume of the chemical liquid remaining in the atomizer which cannot be atomized, thereby reducing waste.
  • the inclined flow channel 31 is disposed away from the one end of the atomizing sheet 2 with a container interface 32.
  • the bottle opening 102 of the multi-chamber drug storage device 1 is disposed at a position of a container joint 104.
  • a joint 104 is inserted into the container interface 32.
  • the atomizing device further comprises a housing 4, the flow guiding joint 3 being detachably connected to the housing 4, the multi-chamber drug storage device 1 being detachably connected to the flow guiding joint 3.
  • the atomization device further includes a rectifying ring 5 mounted at an end of the flow guiding joint 3 away from the multi-chamber drug storage device 1, the rectifying ring 5 and the The inclined flow path 31 holds the atomizing sheet 2.
  • the atomization device further includes an electronic control unit 6 mounted in the housing 4, and the electric control unit 6 and the guide unit 3 are mounted on the housing 4.
  • the atomizing sheet 2 is electrically connected.
  • the electronic control unit 6 includes a time control element and a voltage control element, and the time control element is electrically connected to the atomizing sheet 2 for controlling the working time of the atomizing sheet 2;
  • the atomizing sheet 2 is electrically connected for supplying an operating voltage to the atomizing sheet 2.
  • Embodiment 5 is a diagrammatic representation of Embodiment 5:
  • the spacer divides the inner cavity of the vial body 101 into three cavities, the spacer further includes a second baffle 112, and the second baffle 112 is located at the First partition 110 and said The second partition plate 112 is slidably connected to the inner wall of the drug storage bottle body 101.
  • the inner cavity of the drug storage bottle body 101 is outwardly extended with a second convex cavity 113.
  • the width of the second convex cavity 113 is greater than the thickness of the second partition 112, and the second convex cavity 113 is located between the first convex cavity 111 and the rear partition 114.
  • the sum of the thickness of the rear partition 114 and the thickness of the second partition 112 is greater than the width of the second convex cavity 113.
  • the first partition 110 and the second partition 112 divide the inner cavity of the vial body 101 into a first volume 105, a second volume 106 and a third volume 107.
  • the second partition 112 is located on a side of the second convex cavity 113 away from the bottle opening 102 of the drug storage bottle body 101.
  • the width of the first convex cavity 111 is equal to the width of the second convex cavity 113
  • the thickness of the first partition 110 is equal to the thickness of the second partition 112.
  • the spacer may also divide the inner cavity of the vial body 101 into four or more cavities.
  • the number of the first convex cavities is two, and the two first convex cavities are equally spaced along the circumferential direction of the drug storage bottle body, all of the first convex cavity and the The distance between the mouths of the drug storage bottle body is equal. Providing a plurality of the first convex cavities can increase the conduction area between different cavities and improve the efficiency of mixing.
  • the number of the first convex cavities is two, the number of the second convex cavities is two, and the two first convex cavities are equally spaced along the circumferential direction of the drug storage bottle body. Distribution, all of the first protrusions The distance between the cavity and the mouth of the drug storage bottle body is equal; two of the second convex cavity are equally spaced along the circumferential direction of the drug storage bottle body, and all of the second convex volume The distance between the cavity and the mouth of the drug storage bottle body is equal, and the distance between the second convex cavity and the bottle mouth of the drug storage bottle body is greater than the first convex cavity and the cavity The distance between the mouths of the storage bottle body.
  • the number of the first convex cavities may be 3 or 4 or 5 or 6 or 7 or 8 or 9 or 10; the second convex cavity The number can be 3 or 4 or 5 or 6 or 7 or 8 or 9 or 10.
  • the flow path on the flow guiding joint 3 is a horizontal flow path, and the horizontal flow path is in communication with the atomizing sheet 2, and the multi-chamber drug storage device 1 is installed in the The horizontal flow path is away from the side of the atomizing sheet 2.
  • the axial line of the horizontal flow path is parallel to the horizontal plane, and the axial line of the multi-chamber drug storage device 1 is on the same line as the axial line of the horizontal flow path.

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Abstract

一种多腔式雾化设备，包括用于储存药剂的多腔式储药装置（1），多腔式储药装置（1）包括储药瓶体（101），储药瓶体（101）的内腔设置有隔离件，隔离件将储药瓶体（101）的内腔分隔成至少两个容腔，隔离件受到外部压力后隔离功能将会被破坏而使不同的容腔导通，药物使用前，不同的容腔之间相互隔断，药物使用时，不同的容腔之间相互导通，从而实现使用前使药剂的有效成分与溶液处于分离状态，使用时施加外部压力即可混合的效果，提高药剂的作用效果。

Description

一种多腔式雾化设备 技术领域
本发明涉及医疗器械技术领域，尤其涉及一种多腔式雾化设备。
背景技术
随着工业化和城市化的不断发展和深入，城市的空气质量越来越差，人们的呼吸系统疾病越来越普遍和频繁。医疗器械中包括一种产品是雾化器，雾化器主要用于治疗各种上下呼吸系统疾病，如感冒、发热、咳嗽、哮喘、咽喉肿痛、咽炎、鼻炎、支气管炎、尘肺等气管、支气管、肺泡、胸腔内所发生的疾病。雾化吸入治疗是呼吸系统疾病治疗方法中一种重要和有效的治疗方法，采用雾化器将药液雾化成微小颗粒，药物通过呼吸吸入的方式进入呼吸道和肺部沉积，从而达到无痛、迅速有效治疗的目的。
目前，雾化器的储药装置均为单腔式，而在实际使用中，有些药物的稳定性较差，在储存时需要将药剂的有效成分与溶液相分离，只有在使用时才将药剂与溶液混合，以保证药剂的作用效果最佳。但在雾化器领域的现有技术中并未提供这样的可将药剂与溶液分离的储药装置，对于稳定性较差的药物，存在药效降低甚至失效的风险。
基于上述情况，我们有必要设计一种能够解决上述问题的储药装置和雾化器。
发明内容
本发明的目的在于：提供一种多腔式雾化设备，使用前可使药剂的有效成 分与溶液处于分离状态，待使用时才混合，提高药剂的作用效果。
为达此目的，本发明采用以下技术方案：
一种多腔式雾化设备，包括用于储存药剂的多腔式储药装置，所述多腔式储药装置包括储药瓶体，所述储药瓶体的内腔设置有隔离件，所述隔离件将所述储药瓶体的内腔分隔成至少两个容腔，药物使用前，不同的所述容腔之间相互隔断，药物使用时，不同的所述容腔之间相互导通。
具体地，所述隔离件受到外部压力后隔离功能将会被破坏而使不同的容腔导通，从而实现使用前使药剂的有效成分与溶液处于分离状态，使用时施加外部压力即可混合的效果，提高药剂的作用效果。
具体地，所述隔离件和所述容腔的个数根据药剂的种类任意选择和设计。
作为一种优选的技术方案，所述储药瓶体由塑性变形材料制成，所述隔离件包括第一密封膜，所述第一密封膜与所述储药瓶体的内壁固定连接。
优选的，所述第一密封膜将所述储药瓶体的内腔分隔成第一容腔和第二容腔。
优选的，所述第一密封膜是柔性密封膜，所述第一密封膜在外力挤压下容易破裂。具体地，使用时向所述储药瓶体的侧壁施加外力，逼迫所述储药瓶体发生形变，从而使所述第一密封膜破裂，使所述第一容腔与所述第二容腔导通。
优选的，所述第一密封膜设置在所述储药瓶体的瓶口与瓶底之间。
作为一种优选的技术方案，所述隔离件还包括第二密封膜，所述第二密封膜位于所述第一密封膜与所述储药瓶体的瓶底之间，所述第二密封膜与所述储药瓶体的内壁固定连接。
优选的，所述第一密封膜和所述第二密封膜将所述储药瓶体的内腔分隔成第一容腔、第二容腔和第三容腔。
优选的，所述第二密封膜是柔性密封膜，所述第二密封膜在外力挤压下容易破裂。具体地，使用时向所述储药瓶体的侧壁施加外力，逼迫所述储药瓶体发生形变，从而使所述第一密封膜和第二密封膜破裂，使所述第一容腔、所述第二容腔与所述第三容腔导通。
优选的，所述隔离件还包括第三密封膜，所述第三密封膜位于所述第二密封膜与所述储药瓶体的瓶底之间，所述第三密封膜与所述储药瓶体的内壁固定连接，所述第三密封膜是柔性密封膜。所述第一密封膜、所述第二密封膜和第三密封膜将所述储药瓶体的内腔分隔成第一容腔、第二容腔、第三容腔和第四容腔。
具体地，密封膜和容腔的个数可以根据待混合的药物种类的数量进行选择，以满足多种不同药物的存储。
作为一种优选的技术方案，所述储药瓶体由刚性材料制成，所述隔离件包括第一隔板，所述第一隔板与所述储药瓶体的内壁滑动连接，所述储药瓶体的内腔向外延伸设置有至少一个第一凸起容腔，所述第一凸起容腔的宽度大于所述第一隔板的厚度，所述储药瓶体的内腔并位于所述隔离件远离所述储药瓶体的瓶口的一侧设置有后隔板，所述后隔板与所述储药瓶体的内壁滑动连接，所述后隔板的厚度与所述第一隔板的厚度之和大于所述第一凸起容腔的宽度。
优选的，所述第一隔板将所述储药瓶体的内腔分隔成第一容腔和第二容腔。
优选的，药物使用前，所述第一隔板位于所述第一凸起容腔远离所述储药瓶体的瓶口的一侧。使用时，向所述后隔板施加外力，驱动所述后隔板向靠近所述第一隔板的方向移动，当所述第二容腔内的药剂被压缩至一定程度后，所述后隔板将通过压缩的药剂驱动所述第一隔板向所述第一凸起容腔的方向移动，直到所述第一隔板到达所述第一凸起容腔的位置，由于所述第一凸起容腔 的宽度大于所述第一隔板的厚度，因此，所述第一凸起容腔在所述第一隔板的两侧形成导通间隔，使所述第一容腔与所述第二容腔导通，此时所述第二容腔内的压力被释放，无法继续驱动所述第一隔板移动，使所述第一隔板停留在所述第一凸起容腔的位置，从而使所述第一容腔与所述第二容腔保持导通状态，最终使所述后隔板与所述第一隔板贴合，此时停止对所述后隔板施加外力。由于所述后隔板的厚度与所述第一隔板的厚度之和大于所述第一凸起容腔的宽度，因此所述导通间隙被封闭，使药剂不能从所述后隔板泄漏，从而避免药剂浪费和保证药剂卫生。不同容腔的药剂混合后，轻轻摇动所述多腔式储药装置，使药剂混合均匀，然后将所述多腔式储药装置与雾化设备连接，即可进行雾化处理。
具体地，所述第一凸起容腔的宽度是指所述第一凸起容腔沿所述储药瓶体的瓶口与瓶底的连线方向的尺寸；所述第一隔板的厚度是指所述第一隔板沿所述储药瓶体的瓶口与瓶底的连线方向的尺寸。
作为一种优选的技术方案，所述隔离件还包括第二隔板，所述第二隔板位于所述第一隔板与所述后隔板之间，所述第二隔板与所述储药瓶体的内壁滑动连接，所述储药瓶体的内腔向外延伸设置有至少一个第二凸起容腔，所述第二凸起容腔的宽度大于所述第二隔板的厚度，所述第二凸起容腔位于所述第一凸起容腔与所述后隔板之间，所述后隔板的厚度与所述第二隔板的厚度之和大于所述第二凸起容腔的宽度。
优选的，所述第一隔板和所述第二隔板将所述储药瓶体的内腔分隔成第一容腔、第二容腔和第三容腔。
优选的，药物使用前，所述第二隔板位于所述第二凸起容腔远离所述储药瓶体的瓶口的一侧。
具体地，所述第一凸起容腔的宽度是指所述第一凸起容腔沿所述储药瓶体的瓶口与瓶底的连线方向的尺寸；所述第一隔板的厚度是指所述第一隔板沿所述储药瓶体的瓶口与瓶底的连线方向的尺寸。
优选的，所述第一凸起容腔的宽度与所述第二凸起容腔的宽度相等，所述第一隔板的厚度与所述第二隔板的厚度相等。
作为一种优选的技术方案，若干所述第一凸起容腔沿所述储药瓶体的圆周方向等间隔分布，全部所述第一凸起容腔与所述储药瓶体的瓶口之间的距离相等；若干所述第二凸起容腔沿所述储药瓶体的圆周方向等间隔分布，全部所述第二凸起容腔与所述储药瓶体的瓶口之间的距离相等，所述第二凸起容腔与所述储药瓶体的瓶口之间的距离大于所述第一凸起容腔与所述储药瓶体的瓶口之间的距离。
优选的，所述第一凸起容腔的数量是1个或2个或3个或4个或5个或6个或7个或8个或9个或10个。
优选的，所述第二凸起容腔的数量是1个或2个或3个或4个或5个或6个或7个或8个或9个或10个。
优选的，所述第一凸起容腔的个数与所述第二凸起容腔的个数相等。
具体地，设置若干所述第一凸起容腔和所述第二凸起容腔能够增大不同容腔之间的导通面积，提高混合的效率。
作为一种优选的技术方案，还包括雾化片和导流接头，所述雾化片安装在所述导流接头的一端，所述导流接头上开设有倾斜流道，所述倾斜流道与所述雾化片连通，所述多腔式储药装置安装在所述倾斜流道远离所述雾化片的一侧，所述倾斜流道沿靠近所述雾化片的一端向靠近所述多腔式储药装置的一端向上倾斜。
处于雾化片正常工作的液位标定线以下的药液的总残留量包括两部分，第一部分是所述倾斜流道内的残留量，第二部分是所述导流接头远离所述储液容器一端的安装凹槽内的残留量。其中，第一部分的残留量随所述倾斜流道的倾斜角度增大而减少，因此，本方案通过导流接头连接雾化片与储液容器，且在导流接头上开设倾斜流道，倾斜设计的倾斜流道能够减少处于雾化片正常工作液位以下的储液空间，有效减少残留在雾化器内无法被雾化的药液体积，从而减少浪费。
当然，所述导流接头上也可以开设水平流道，所述水平流道与所述雾化片连通，所述多腔式储药装置安装在所述水平流道远离所述雾化片的一侧。所述水平流道的轴心线与水平面平行。
作为一种优选的技术方案，所述倾斜流道的轴心线与水平面之间的夹角是10度以上70度以下。
优选的，所述倾斜流道的轴心线与水平面之间的夹角是15度以上60度以下。
优选的，所述倾斜流道的轴心线与水平面之间的夹角是10度或15度或20度或25度或30度或35度或40度或45度或50度或55度或60度或65度或70度。
具体地，所述倾斜流道靠近所述雾化片一侧的端口形状是椭圆形，在所述倾斜流道靠近所述雾化片一侧的端口的长轴长度固定不变的情况下，随着所述倾斜流道的倾斜角度的增大，所述倾斜流道的直径将会减小。由于液体的表面张力作用，液体在自身重力的作用下不容易通过狭小的空间，即所述倾斜流道的直径越小药液越不易通过所述倾斜流道，因此所述倾斜流道的直径不能够太小，以免药液不能顺利通过。根据上述分析，所述倾斜流道的倾斜角度不能太 大，否则会造成药液不能顺利通过所述倾斜流道造成药液供给不足。
作为一种优选的技术方案，所述倾斜流道远离所述雾化片的一端设置有容器接口，所述多腔式储药装置的瓶口位置设置有容器接头，所述容器接头插装在所述容器接口内。
作为一种优选的技术方案，所述容器接口的轴心线与所述倾斜流道的轴心线位于同一直线上；
或者，所述容器接口的轴心线与水平面平行；
或者，所述容器接口的轴心线与水平面垂直。
作为一种优选的技术方案，所述多腔式储药装置与所述导流接头可拆卸式连接。
作为一种优选的技术方案，还包括壳体，所述导流接头可拆卸式连接于所述壳体上。
本发明的有益效果为：提供一种多腔式雾化设备，通过在储药瓶体的内腔设置有隔离件，将所述储药瓶体的内腔分隔成至少两个容腔，所述隔离件受到外部压力后隔离功能将会被破坏而使不同的容腔导通，从而实现使用前使药剂的有效成分与溶液处于分离状态，使用时施加外部压力即可混合的效果，提高药剂的作用效果。
附图说明
下面根据附图和实施例对本发明作进一步详细说明。
图1为实施例一所述的多腔式储药装置的剖视示意图；
图2为实施例所述的雾化设备的结构示意图；
图3为实施例所述的雾化设备的爆炸图；
图4为实施例所述的导流接头的剖视示意图；
图5为实施例所述的导流接头、多腔式储药装置、整流环的剖视示意图；
图6为实施例二所述的多腔式储药装置的剖视示意图；
图7为实施例四所述的多腔式储药装置的一种状态的剖视示意图；
图8为实施例四所述的多腔式储药装置的另一种状态的剖视示意图；
图9为实施例四所述的多腔式储药装置的又一种状态的剖视示意图；
图10为实施例五所述的多腔式储药装置的剖视示意图；
图11为实施例八所述的雾化设备的结构示意图；
图12为实施例八所述的多腔式储药装置的剖视示意图。
图1至图12中：
1、多腔式储药装置；
101、储药瓶体；102、瓶口；103、瓶底；104、容器接头；
105、第一容腔；106、第二容腔；107、第三容腔；
108、第一密封膜；109、第二密封膜；
110、第一隔板；111、第一凸起容腔；112、第二隔板；113、第二凸起容腔；114、后隔板；115、导通间隔；
2、雾化片；
3、导流接头；31、倾斜流道；32、容器接口；
4、壳体；
5、整流环；
6、电控组件。
具体实施方式
下面结合附图并通过具体实施方式来进一步说明本发明的技术方案。
实施例一：
一种多腔式雾化设备，包括多腔式储药装置1，如图1所示，多腔式储药装置1包括储药瓶体101，所述储药瓶体101的内腔设置有隔离件，所述隔离件将所述储药瓶体101的内腔分隔成两个容腔，药物使用前，不同的所述容腔之间相互隔断，药物使用时，不同的所述容腔之间相互导通。具体地，所述隔离件受到外部压力后隔离功能将会被破坏而使不同的容腔导通，从而实现使用前使药剂的有效成分与溶液处于分离状态，使用时施加外部压力即可混合的效果，提高药剂的作用效果。
于本实施例中，所述储药瓶体101由塑性变形材料制成，所述隔离件包括第一密封膜108，所述第一密封膜108与所述储药瓶体101的内壁固定连接，所述第一密封膜108设置在所述储药瓶体101的瓶口102与瓶底103之间，所述第一密封膜108将所述储药瓶体101的内腔分隔成第一容腔105和第二容腔106。所述第一密封膜108是柔性密封膜，所述第一密封膜108在外力挤压下容易破裂。具体地，使用时向所述储药瓶体101的侧壁施加外力，逼迫所述储药瓶体101发生形变，从而使所述第一密封膜108破裂，使所述第一容腔105与所述第二容腔106导通。
如图2至图5所示，该多腔式雾化装置还包括雾化片2和导流接头3，所述雾化片2安装在所述导流接头3的一端，所述导流接头3上开设有倾斜流道31，所述倾斜流道31与所述雾化片2连通，所述多腔式储药装置1安装在所述倾斜流道31远离所述雾化片2的一侧，所述倾斜流道31沿靠近所述雾化片2的一端向靠近所述多腔式储药装置1的一端向上倾斜。于本实施例中，所述倾斜流道31的轴心线与水平面之间的夹角是10度。
处于雾化片2正常工作的液位标定线以下的药液的总残留量包括两部分，第一部分是所述倾斜流道31内的残留量，第二部分是所述导流接头3远离所述储液容器一端的安装凹槽内的残留量。其中，第一部分的残留量随所述倾斜流道31的倾斜角度增大而减少，因此，本方案通过导流接头3连接雾化片2与储液容器，且在导流接头3上开设倾斜流道31，倾斜设计的倾斜流道31能够减少处于雾化片2正常工作液位以下的储液空间，有效减少残留在雾化器内无法被雾化的药液体积，从而减少浪费。
于本实施例中，所述倾斜流道31远离所述雾化片2的一端设置有容器接口32，所述多腔式储药装置1的瓶口102位置设置有容器接头104，所述容器接头104插装在所述容器接口32内。所述容器接口32的轴心线与所述倾斜流道31的轴心线位于同一直线上。于其它实施例中，所述容器接口的轴心线与水平面平行；或者，所述容器接口的轴心线与水平面垂直。
于本实施例中，该雾化设备还包括壳体4，所述导流接头3可拆卸式连接于所述壳体4上，所述多腔式储药装置1与所述导流接头3可拆卸式连接。
于本实施例中，该雾化设备还包括整流环5，所述整流环5安装在所述导流接头3远离所述多腔式储药装置1的一端，所述整流环5与所述倾斜流道31夹持所述雾化片2。该雾化设备还包括电控组件6，所述电控组件6安装于所述壳体4内，所述导流接头3安装于所述壳体4上时，所述电控组件6与所述雾化片2电连接。所述电控组件6包括时间控制元件和电压控制元件，所述时间控制元件与所述雾化片2电连接，用于控制所述雾化片2的工作时间；所述电压控制元件与所述雾化片2电连接，用于给所述雾化片2提供工作电压。具体地，在雾化片2物理结构确定的情况下，所述雾化片2在一个恒定的工作电压下工作时，所述雾化片2的雾化效率是固化不变的，因此，在所述雾化片2的工作 时间受控并为确定值的情况下，所述雾化片2实现的药物雾化总量是固定的，且雾化总量等于雾化效率与工作时间的乘积。因此，本方案通过控制雾化效率和工作时间，能够控制治疗药物的雾化总量，提高病患用药的准确性。
实施例二：
本实施例与实施例一的区别在于：
如图6所示，所述隔离件将所述储药瓶体101的内腔分隔成三个容腔，所述隔离件还包括第二密封膜109，所述第二密封膜109位于所述第一密封膜108与所述储药瓶体101的瓶底103之间，所述第二密封膜109与所述储药瓶体101的内壁固定连接，所述第一密封膜108和所述第二密封膜109将所述储药瓶体101的内腔分隔成第一容腔105、第二容腔106和第三容腔107。所述第二密封膜109是柔性密封膜，所述第二密封膜109在外力挤压下容易破裂。具体地，使用时向所述储药瓶体101的侧壁施加外力，逼迫所述储药瓶体101发生形变，从而使所述第一密封膜108和第二密封膜109破裂，使所述第一容腔105、所述第二容腔106与所述第三容腔107导通。
实施例三：
本实施例与实施例二的区别在于：
所述隔离件将所述储药瓶体的内腔分隔成四个容腔，所述隔离件还包括第三密封膜，所述第三密封膜位于所述第二密封膜与所述储药瓶体的瓶底之间，所述第三密封膜与所述储药瓶体的内壁固定连接，所述第三密封膜是柔性密封膜。所述第一密封膜、所述第二密封膜和第三密封膜将所述储药瓶体的内腔分隔成第一容腔、第二容腔、第三容腔和第四容腔。于其它实施例中，所述隔离 件还可以将所述储药瓶体的内腔分隔成五个或者更多的容腔。
实施例四：
一种多腔式雾化设备，包括多腔式储药装置1，如图7至图9所示，多腔式储药装置1包括储药瓶体101，所述储药瓶体101的内腔设置有隔离件，所述隔离件将所述储药瓶体101的内腔分隔成两个容腔，药物使用前，不同的所述容腔之间相互隔断，药物使用时，不同的所述容腔之间相互导通。具体地，所述隔离件受到外部压力后隔离功能将会被破坏而使不同的容腔导通，从而实现使用前使药剂的有效成分与溶液处于分离状态，使用时施加外部压力即可混合的效果，提高药剂的作用效果。
于本实施例中，所述储药瓶体101由刚性材料制成，所述隔离件包括第一隔板110，所述第一隔板110与所述储药瓶体101的内壁滑动连接，所述储药瓶体101的内腔向外延伸设置有一个第一凸起容腔111，所述第一凸起容腔111的宽度大于所述第一隔板110的厚度，所述储药瓶体101的内腔并位于所述隔离件远离所述储药瓶体101的瓶口102的一侧设置有后隔板114，所述后隔板114与所述储药瓶体101的内壁滑动连接，所述后隔板114的厚度与所述第一隔板110的厚度之和大于所述第一凸起容腔111的宽度。其中，所述第一凸起容腔111的宽度是指所述第一凸起容腔111沿所述储药瓶体101的瓶口102与瓶底103的连线方向的尺寸；所述第一隔板110的厚度是指所述第一隔板110沿所述储药瓶体101的瓶口102与瓶底103的连线方向的尺寸。
所述第一隔板110将所述储药瓶体101的内腔分隔成第一容腔105和第二容腔10G。药物使用前，所述第一隔板110位于所述第一凸起容腔111远离所述储药瓶体101的瓶口102的一侧。使用时，向所述后隔板114施加外力，驱动 所述后隔板114向靠近所述第一隔板110的方向移动，当所述第二容腔10G内的药剂被压缩至一定程度后，所述后隔板114将通过压缩的药剂驱动所述第一隔板110向所述第一凸起容腔111的方向移动，直到所述第一隔板110到达所述第一凸起容腔111的位置，由于所述第一凸起容腔111的宽度大于所述第一隔板110的厚度，因此，所述第一凸起容腔111在所述第一隔板110的两侧形成导通间隔115，使所述第一容腔105与所述第二容腔10G导通，此时所述第二容腔10G内的压力被释放，无法继续驱动所述第一隔板110移动，使所述第一隔板110停留在所述第一凸起容腔111的位置，从而使所述第一容腔105与所述第二容腔10G保持导通状态，最终使所述后隔板114与所述第一隔板110贴合，此时停止对所述后隔板114施加外力。由于所述后隔板114的厚度与所述第一隔板110的厚度之和大于所述第一凸起容腔111的宽度，因此所述导通间隙115被封闭，使药剂不能从所述后隔板114泄漏，从而避免药剂浪费和保证药剂卫生。不同容腔的药剂混合后，轻轻摇动所述多腔式储药装置，使药剂混合均匀，然后将所述多腔式储药装置与雾化设备连接，即可进行雾化处理。
如图2至图5所示，该多腔式雾化装置还包括雾化片2和导流接头3，所述雾化片2安装在所述导流接头3的一端，所述导流接头3上开设有倾斜流道31，所述倾斜流道31与所述雾化片2连通，所述多腔式储药装置1安装在所述倾斜流道31远离所述雾化片2的一侧，所述倾斜流道31沿靠近所述雾化片2的一端向靠近所述多腔式储药装置1的一端向上倾斜。于本实施例中，所述倾斜流道31的轴心线与水平面之间的夹角是70度。于其它实施例中，所述倾斜流道的轴心线与水平面之间的夹角还可以是15度或20度或25度或30度或35度或40度或45度或50度或55度或60度或65度。
处于雾化片2正常工作的液位标定线以下的药液的总残留量包括两部分， 第一部分是所述倾斜流道31内的残留量，第二部分是所述导流接头3远离所述储液容器一端的安装凹槽内的残留量。其中，第一部分的残留量随所述倾斜流道31的倾斜角度增大而减少，因此，本方案通过导流接头3连接雾化片2与储液容器，且在导流接头3上开设倾斜流道31，倾斜设计的倾斜流道31能够减少处于雾化片2正常工作液位以下的储液空间，有效减少残留在雾化器内无法被雾化的药液体积，从而减少浪费。
于本实施例中，所述倾斜流道31远离所述雾化片2的一端设置有容器接口32，所述多腔式储药装置1的瓶口102位置设置有容器接头104，所述容器接头104插装在所述容器接口32内。该雾化设备还包括壳体4，所述导流接头3可拆卸式连接于所述壳体4上，所述多腔式储药装置1与所述导流接头3可拆卸式连接。
于本实施例中，该雾化设备还包括整流环5，所述整流环5安装在所述导流接头3远离所述多腔式储药装置1的一端，所述整流环5与所述倾斜流道31夹持所述雾化片2。该雾化设备还包括电控组件6，所述电控组件6安装于所述壳体4内，所述导流接头3安装于所述壳体4上时，所述电控组件6与所述雾化片2电连接。所述电控组件6包括时间控制元件和电压控制元件，所述时间控制元件与所述雾化片2电连接，用于控制所述雾化片2的工作时间；所述电压控制元件与所述雾化片2电连接，用于给所述雾化片2提供工作电压。
实施例五：
本实施例与实施例四的区别在于：
如图10所示，所述隔离件将所述储药瓶体101的内腔分隔成三个容腔，所述隔离件还包括第二隔板112，所述第二隔板112位于所述第一隔板110与所述 后隔板114之间，所述第二隔板112与所述储药瓶体101的内壁滑动连接，所述储药瓶体101的内腔向外延伸设置有一个第二凸起容腔113，所述第二凸起容腔113的宽度大于所述第二隔板112的厚度，所述第二凸起容腔113位于所述第一凸起容腔111与所述后隔板114之间，所述后隔板114的厚度与所述第二隔板112的厚度之和大于所述第二凸起容腔113的宽度。所述第一隔板110和所述第二隔板112将所述储药瓶体101的内腔分隔成第一容腔105、第二容腔106和第三容腔107。药物使用前，所述第二隔板112位于所述第二凸起容腔113远离所述储药瓶体101的瓶口102的一侧。所述第一凸起容腔111的宽度与所述第二凸起容腔113的宽度相等，所述第一隔板110的厚度与所述第二隔板112的厚度相等。于其它实施例中，所述隔离件还可以将所述储药瓶体101的内腔分隔成四个或者更多的容腔。
实施例六：
本实施例与实施例四的区别在于：
所述第一凸起容腔的数量是2个，两个所述第一凸起容腔沿所述储药瓶体的圆周方向等间隔分布，全部所述第一凸起容腔与所述储药瓶体的瓶口之间的距离相等。设置多个所述第一凸起容腔能够增大不同容腔之间的导通面积，提高混合的效率。
实施例七：
本实施例与实施例五的区别在于：
所述第一凸起容腔的数量是2个，所述第二凸起容腔的数量是2个，两个所述第一凸起容腔沿所述储药瓶体的圆周方向等间隔分布，全部所述第一凸起 容腔与所述储药瓶体的瓶口之间的距离相等；两个所述第二凸起容腔沿所述储药瓶体的圆周方向等间隔分布，全部所述第二凸起容腔与所述储药瓶体的瓶口之间的距离相等，所述第二凸起容腔与所述储药瓶体的瓶口之间的距离大于所述第一凸起容腔与所述储药瓶体的瓶口之间的距离。设置多个所述第一凸起容腔和所述第二凸起容腔能够增大不同容腔之间的导通面积，提高混合的效率。于其它实施例中，所述第一凸起容腔的数量可以是3个或4个或5个或6个或7个或8个或9个或10个；所述第二凸起容腔的数量可以是3个或4个或5个或6个或7个或8个或9个或10个。
实施例八：
本实施例与实施例一的区别在于：
如图11和图12所示，所述导流接头3上的流道是水平流道，所述水平流道与所述雾化片2连通，所述多腔式储药装置1安装在所述水平流道远离所述雾化片2的一侧。所述水平流道的轴心线与水平面平行，所述多腔式储药装置1的轴心线与所述水平流道的轴心线在同一条直线上。
本文中的“第一”、“第二”、“第三”、“第四”仅仅是为了在描述上加以区分，并没有特殊的含义。
需要声明的是，上述具体实施方式仅仅为本发明的较佳实施例及所运用技术原理，在本发明所公开的技术范围内，任何熟悉本技术领域的技术人员所容易想到的变化或替换，都应涵盖在本发明的保护范围内。

Claims (10)

  1. 一种多腔式雾化设备，其特征在于，包括用于储存药剂的多腔式储药装置，所述多腔式储药装置包括储药瓶体，所述储药瓶体的内腔设置有隔离件，所述隔离件将所述储药瓶体的内腔分隔成至少两个容腔，药物使用前，不同的所述容腔之间相互隔断，药物使用时，不同的所述容腔之间相互导通。
  2. 根据权利要求1所述的一种多腔式雾化设备，其特征在于，所述储药瓶体由塑性变形材料制成，所述隔离件包括第一密封膜，所述第一密封膜与所述储药瓶体的内壁固定连接。
  3. 根据权利要求2所述的一种多腔式雾化设备，其特征在于，所述隔离件还包括第二密封膜，所述第二密封膜位于所述第一密封膜与所述储药瓶体的瓶底之间，所述第二密封膜与所述储药瓶体的内壁固定连接。
  4. 根据权利要求1所述的一种多腔式雾化设备，其特征在于，所述储药瓶体由刚性材料制成，所述隔离件包括第一隔板，所述第一隔板与所述储药瓶体的内壁滑动连接，所述储药瓶体的内腔向外延伸设置有至少一个第一凸起容腔，所述第一凸起容腔的宽度大于所述第一隔板的厚度，所述储药瓶体的内腔并位于所述隔离件远离所述储药瓶体的瓶口的一侧设置有后隔板，所述后隔板与所述储药瓶体的内壁滑动连接，所述后隔板的厚度与所述第一隔板的厚度之和大于所述第一凸起容腔的宽度。
  5. 根据权利要求4所述的一种多腔式雾化设备，其特征在于，所述隔离件还包括第二隔板，所述第二隔板位于所述第一隔板与所述后隔板之间，所述第二隔板与所述储药瓶体的内壁滑动连接，所述储药瓶体的内腔向外延伸设置有至少一个第二凸起容腔，所述第二凸起容腔的宽度大于所述第二隔板的厚度，所述第二凸起容腔位于所述第一凸起容腔与所述后隔板之间，所述后隔板的厚度与所述第二隔板的厚度之和大于所述第二凸起容腔的宽度。
  6. 根据权利要求5所述的一种多腔式雾化设备，其特征在于，若干所述第一凸起容腔沿所述储药瓶体的圆周方向等间隔分布，全部所述第一凸起容腔与所述储药瓶体的瓶口之间的距离相等；若干所述第二凸起容腔沿所述储药瓶体的圆周方向等间隔分布，全部所述第二凸起容腔与所述储药瓶体的瓶口之间的距离相等，所述第二凸起容腔与所述储药瓶体的瓶口之间的距离大于所述第一凸起容腔与所述储药瓶体的瓶口之间的距离。
  7. 根据权利要求1所述的一种多腔式雾化设备，其特征在于，还包括雾化片和导流接头，所述雾化片安装在所述导流接头的一端，所述导流接头上开设有倾斜流道，所述倾斜流道与所述雾化片连通，所述多腔式储药装置安装在所述倾斜流道远离所述雾化片的一侧，所述倾斜流道沿靠近所述雾化片的一端向靠近所述多腔式储药装置的一端向上倾斜。
  8. 根据权利要求7所述的一种多腔式雾化设备，其特征在于，所述倾斜流道的轴心线与水平面之间的夹角是10度以上70度以下。
  9. 根据权利要求7所述的一种多腔式雾化设备，其特征在于，所述多腔式储药装置与所述导流接头可拆卸式连接。
  10. 根据权利要求7所述的一种多腔式雾化设备，其特征在于，还包括壳体，所述导流接头可拆卸式连接于所述壳体上。
PCT/CN2017/106286 2016-10-17 2017-10-16 一种多腔式雾化设备 Ceased WO2018072665A1 (zh)

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