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WO2017214823A1 - Kit de réactifs présentant des fonctions d'isolation contre le froid, d'affichage de température, d'alarme et de rappel d'ajout d'échantillons - Google Patents

Kit de réactifs présentant des fonctions d'isolation contre le froid, d'affichage de température, d'alarme et de rappel d'ajout d'échantillons Download PDF

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Publication number
WO2017214823A1
WO2017214823A1 PCT/CN2016/085627 CN2016085627W WO2017214823A1 WO 2017214823 A1 WO2017214823 A1 WO 2017214823A1 CN 2016085627 W CN2016085627 W CN 2016085627W WO 2017214823 A1 WO2017214823 A1 WO 2017214823A1
Authority
WO
WIPO (PCT)
Prior art keywords
reagent
kit
temperature display
temperature
alarm
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2016/085627
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English (en)
Chinese (zh)
Inventor
石庆学
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to PCT/CN2016/085627 priority Critical patent/WO2017214823A1/fr
Publication of WO2017214823A1 publication Critical patent/WO2017214823A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00—Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/02—Internal fittings
    • B65D25/10—Devices to locate articles in containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/18—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient

Definitions

  • the present invention relates to the field of biotechnology, and more particularly to a kit having a cold retention, temperature display and alarm, and a sample reminder function.
  • kits In the field of biotechnology, in addition to technical breakthroughs, it is more important to improve the efficiency of research and experimentation. Among them, the emergence of kits plays an important role.
  • the kit standardizes the steps of common biological experiments, providing the experimenter with the reagents to be prepared and the optimized loading method, which greatly increases the speed of the experimental development and the degree of standardization of the results.
  • the complexity of the experiment is increasing, the number of reagents in the existing kits is also increasing, and the loading step is becoming more and more complicated.
  • the general kit contains Taq enzyme, buffer, chromogenic dye and sterile ultrapure water.
  • the reagents required by the experimenter include at least the upstream primer. Downstream primers and template, a total of 7 reagents together to prepare a fluorescent quantitative PCR reaction system.
  • the experimenter will have the phenomenon of missing, adding, adding, etc. during the process of adding samples. The reason is that there are many kinds of reagents, and the process of loading cannot be well identified and marked. ⁇ Handling other urgent matters and causing the ongoing experiment to be interrupted, the error is in the office Inevitably.
  • the present invention provides a kit having a cold retention, temperature display and alarm, and a sample reminder function.
  • kits with cold preservation, temperature display and alarm, and sample reminding function comprising a kit body and a lid, wherein the kit body is provided with a sounding device and a control Unit, small battery and display unit.
  • the sounding device, the control unit and the battery are electrically connected; the display device, the control unit and the battery are electrically connected; the outer wall of the reagent hole is provided with a refrigeration device and a temperature control probe, and the refrigeration device and the temperature control probe Electrical connection with the control unit.
  • the inner layer of the kit body is further provided with a lining plate, and the lining plate is provided with a pipette tip head collecting hole and a reagent rotating disk, and an arrow indicator light is further disposed between the two.
  • the lining plate is spaced apart from the mouth of the box body such that the lining plate forms a clogging space with the box body; the reagent rotating disk is provided with a plurality of reagent holes, And connected to a power mechanism.
  • the reagent box body is further provided with an inductor, the sensor is disposed corresponding to a bottom of the pipette tip head collecting hole, and the sensor receives the hole by sensing the pipette tip head The bottom controls the rotation of the reagent rotating disk and the color of the arrow indicator light.
  • kit body has a two-layer structure, and the control unit, the sounding device and the small power storage battery are disposed between the inner layer and the outer layer of the reagent cartridge body.
  • the number of the reagent wells is six.
  • the display device is a digital display screen.
  • the sounding device is a buzzer, and the number is two.
  • control unit is a single chip microcomputer.
  • the small battery is a lithium ion battery.
  • the inductor is connected to the bottom of the pipette tip collecting hole by a spring.
  • the reagent rotating disk is provided with 8 reagent holes; the power mechanism connected thereto is a stepping motor, and is connected to the inductor and controlled by the inductor.
  • the arrow indicator material is an LED, connected to the sensor, and controlled by the sensor
  • the present invention provides a required pre-cooling environment (2-8 ° C) for the reagent by providing a sounding device, a control unit and a battery in the kit body and a refrigeration device and a temperature control probe on the outer wall of the reagent hole, and The temperature can be detected by a temperature-controlled probe and presented to the experimenter via a display device. Once the setting range is exceeded, the sounding device immediately alerts the experimenter to reduce the probability of failure of the experiment; meanwhile, the reagent hole is rotated by the reagent disk, which can serve as an additive reminder for the experimenter, avoiding the mistake of adding the wrong sample. The experiment failed.
  • 2 is a structural diagram of the reagent well.
  • FIG. 3 is a schematic view showing the structure of a reagent rotating disk, an arrow indicator lamp, and a pipette tip head collecting hole as shown in FIG. 1.
  • a kit having a cold preservation, temperature display and alarm, and a sample reminding function includes a kit body 10 and a lid 20, and the kit body is provided with a liner 30 and sounding
  • the sounding device, the control unit and the battery are electrically connected; the display device, the control unit and the battery are electrically connected.
  • the outer wall of the reagent hole is provided with a refrigerating device 381 and a temperature control probe 382, and the refrigerating device, the temperature control probe and the control unit are electrically connected.
  • the lining plate 30 is provided with a pipette tip collecting hole 32 and a reagent rotating disk 36, and an arrow indicator light 34 is further disposed between the two, and the reagent rotating disk 36 is disposed on the reagent rotating plate 36.
  • Sensor 60 Placed in the casing 10 the inductor 60 is disposed corresponding to the bottom of the pipette tip collecting hole 32, and the inductor 60 controls the stepping motor 70 to drive the reagent rotating disk through the bottom of the inductive pipette tip collecting hole 32.
  • the rotation of 36 and the color of the arrow indicator light 34 are illuminated.
  • the inductor 60 is connected to the bottom of the pipette tip collecting hole 32 by the spring 50.
  • the sensor 60 controls the stepping motor 70 to drive the reagent rotation by inducing the pipette tip to collect the bottom of the hole 32.
  • the color of the disk 36 is rotated and the arrow indicator light 34 is illuminated.
  • the color of the arrow indicator light 34 is in one-to-one correspondence with the reagent holes on the reagent rotating disk 36.
  • the eight colors of red, orange, yellow, green, cyan, blue, purple, and white correspond to 1-8 on the reagent rotating disk 36, respectively.
  • control stepper motor 70 drives the reagent rotating disk 36 to rotate 45° to its next reagent hole, and controls the arrow indicator. 34 lights up the color of the corresponding reagent hole.
  • the present invention provides a required pre-cooling environment (2-8 ° C) for a reagent by providing a sounding device, a control unit, and a battery in the kit body and a refrigeration device and a temperature control probe on the outer wall of the reagent hole, and The temperature can be detected by a temperature-controlled probe and presented to the experimenter via a display device. Once the setting range is exceeded, the sounding device immediately alerts the experimenter to reduce the probability of failure of the experiment; meanwhile, the reagent hole is rotated by the reagent disk, which can serve as an additive reminder for the experimenter, avoiding the mistake of adding the wrong sample. The experiment failed.
  • the present invention provides a required pre-cooling environment (2-8 ° C) for the reagent by providing a sounding device, a control unit and a battery in the kit body and a refrigeration device and a temperature control probe on the outer wall of the reagent hole, and The temperature can be detected by a temperature-controlled probe and presented to the experimenter via a display device. Once the setting range is exceeded, the sounding device immediately alerts the experimenter to reduce the probability of failure of the experiment; meanwhile, the reagent hole is rotated by the reagent disk, which can serve as an additive reminder for the experimenter, avoiding the mistake of adding the wrong sample. The experiment failed.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

L'invention concerne un kit de réactifs présentant des fonctions d'isolation contre le froid, d'affichage de température, d'alarme et de rappel d'ajout d'échantillons. Par l'agencement de dispositifs de production de son (40), d'une unité de commande et d'une batterie d'accumulateurs sur un corps de kit de réactifs (10) et l'agencement d'un dispositif de réfrigération (381) et d'une sonde de régulation de température (382) sur les parois externes des trous de réactifs (38), un environnement de pré-refroidissement nécessaire (2-8 °C) peut être fourni au réactif, la température peut être détectée au moyen de la sonde de régulation de température (382) et est présentée au personnel de l'expérience au moyen d'un dispositif d'affichage (80). Une fois que la température dépasse une plage prédéfinie, les dispositifs de production de son (40) émettent immédiatement des alarmes de rappel à destination du personnel de l'expérience, ce qui permet de réduire le risque d'échec de l'expérience ; en outre, un plateau à réactifs (36) entraîne les trous de réactifs (38) en rotation, de manière à rappeler au personnel de l'expérience d'ajouter des échantillons, ce qui permet d'éviter tout échec de d'expérience en raison d'erreurs d'ajout d'échantillons.
PCT/CN2016/085627 2016-06-13 2016-06-13 Kit de réactifs présentant des fonctions d'isolation contre le froid, d'affichage de température, d'alarme et de rappel d'ajout d'échantillons Ceased WO2017214823A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/CN2016/085627 WO2017214823A1 (fr) 2016-06-13 2016-06-13 Kit de réactifs présentant des fonctions d'isolation contre le froid, d'affichage de température, d'alarme et de rappel d'ajout d'échantillons

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2016/085627 WO2017214823A1 (fr) 2016-06-13 2016-06-13 Kit de réactifs présentant des fonctions d'isolation contre le froid, d'affichage de température, d'alarme et de rappel d'ajout d'échantillons

Publications (1)

Publication Number Publication Date
WO2017214823A1 true WO2017214823A1 (fr) 2017-12-21

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2016/085627 Ceased WO2017214823A1 (fr) 2016-06-13 2016-06-13 Kit de réactifs présentant des fonctions d'isolation contre le froid, d'affichage de température, d'alarme et de rappel d'ajout d'échantillons

Country Status (1)

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WO (1) WO2017214823A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111409957A (zh) * 2020-03-20 2020-07-14 赵媛 一种自监测防高温损坏的数码产品收纳盒
CN114408360A (zh) * 2022-02-25 2022-04-29 湖北琪谱检测技术有限公司 一种可用于动物血清样本检测的试剂盒及检测方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130025298A1 (en) * 2011-07-28 2013-01-31 Biocision, Inc. Preventing sample degradation from transient temperature fluctuations
CN103988064A (zh) * 2011-09-09 2014-08-13 简.探针公司 自动化样品处理仪器、系统、过程和方法
CN204374216U (zh) * 2014-11-19 2015-06-03 苏州长光华医生物试剂有限公司 一种快速检测乙型肝炎病毒表面抗原的试剂盒
CN204489596U (zh) * 2015-01-23 2015-07-22 新疆维吾尔自治区产品质量监督检验研究院 一种便携式温控试剂箱
CN205015266U (zh) * 2015-09-29 2016-02-03 天津悦和康生物技术有限公司 一种同型半胱氨酸测定试剂盒
CN205246671U (zh) * 2015-12-18 2016-05-18 西藏民族学院 一种乙型肝炎病毒检测试剂盒

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130025298A1 (en) * 2011-07-28 2013-01-31 Biocision, Inc. Preventing sample degradation from transient temperature fluctuations
CN103988064A (zh) * 2011-09-09 2014-08-13 简.探针公司 自动化样品处理仪器、系统、过程和方法
CN204374216U (zh) * 2014-11-19 2015-06-03 苏州长光华医生物试剂有限公司 一种快速检测乙型肝炎病毒表面抗原的试剂盒
CN204489596U (zh) * 2015-01-23 2015-07-22 新疆维吾尔自治区产品质量监督检验研究院 一种便携式温控试剂箱
CN205015266U (zh) * 2015-09-29 2016-02-03 天津悦和康生物技术有限公司 一种同型半胱氨酸测定试剂盒
CN205246671U (zh) * 2015-12-18 2016-05-18 西藏民族学院 一种乙型肝炎病毒检测试剂盒

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111409957A (zh) * 2020-03-20 2020-07-14 赵媛 一种自监测防高温损坏的数码产品收纳盒
CN114408360A (zh) * 2022-02-25 2022-04-29 湖北琪谱检测技术有限公司 一种可用于动物血清样本检测的试剂盒及检测方法

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