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WO2017160124A3 - Recombinant expression vector for producing norovirus vaccine - Google Patents

Recombinant expression vector for producing norovirus vaccine Download PDF

Info

Publication number
WO2017160124A3
WO2017160124A3 PCT/KR2017/002945 KR2017002945W WO2017160124A3 WO 2017160124 A3 WO2017160124 A3 WO 2017160124A3 KR 2017002945 W KR2017002945 W KR 2017002945W WO 2017160124 A3 WO2017160124 A3 WO 2017160124A3
Authority
WO
WIPO (PCT)
Prior art keywords
expression vector
recombinant expression
vaccine
norovirus
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2017/002945
Other languages
French (fr)
Korean (ko)
Other versions
WO2017160124A2 (en
Inventor
성백린
황범증
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inthera Inc
Original Assignee
Inthera Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inthera Inc filed Critical Inthera Inc
Priority claimed from KR1020170033689A external-priority patent/KR101914779B1/en
Publication of WO2017160124A2 publication Critical patent/WO2017160124A2/en
Publication of WO2017160124A3 publication Critical patent/WO2017160124A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The present invention relates to a recombinant expression vector for producing a water-soluble norovirus vaccine, and more particularly, to a recombinant expression vector for producing a water-soluble norovirus vaccine, and a method for using same to produce a water-soluble norovirus vaccine. According to the present invention, a recombinant expression vector and a method for using same to produce a norovirus vaccine can not only efficiently produce a norovirus VLP vaccine from E. coli, but by enabling the production of a VLP that is structurally delicate, allows for the production of an inexpensive and highly efficient norovirus VLP vaccine.
PCT/KR2017/002945 2016-03-18 2017-03-17 Recombinant expression vector for producing norovirus vaccine Ceased WO2017160124A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR10-2016-0032451 2016-03-18
KR20160032451 2016-03-18
KR10-2017-0033689 2017-03-17
KR1020170033689A KR101914779B1 (en) 2016-03-18 2017-03-17 Recombinant Expression Vectors for Producing Norovirus Vaccine

Publications (2)

Publication Number Publication Date
WO2017160124A2 WO2017160124A2 (en) 2017-09-21
WO2017160124A3 true WO2017160124A3 (en) 2018-08-02

Family

ID=59851614

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2017/002945 Ceased WO2017160124A2 (en) 2016-03-18 2017-03-17 Recombinant expression vector for producing norovirus vaccine

Country Status (1)

Country Link
WO (1) WO2017160124A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040016654A (en) * 2002-08-19 2004-02-25 프로테온 주식회사 Method for preparation of recombinant protein using RNA binding protein as fusion partner
KR20080094766A (en) * 2007-12-24 2008-10-24 주식회사 벡손 Method for producing recombinant protein using a new fusion partner
KR20130020206A (en) * 2011-08-19 2013-02-27 연세대학교 산학협력단 Recombinant e. coli producing soluble bmp-2 and method for producing soluble bmp-2 using the same
US20130171185A1 (en) * 2010-07-06 2013-07-04 Ethan Settembre Norovirus derived immunogenic compositions and methods

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040016654A (en) * 2002-08-19 2004-02-25 프로테온 주식회사 Method for preparation of recombinant protein using RNA binding protein as fusion partner
KR20080094766A (en) * 2007-12-24 2008-10-24 주식회사 벡손 Method for producing recombinant protein using a new fusion partner
US20130171185A1 (en) * 2010-07-06 2013-07-04 Ethan Settembre Norovirus derived immunogenic compositions and methods
KR20130020206A (en) * 2011-08-19 2013-02-27 연세대학교 산학협력단 Recombinant e. coli producing soluble bmp-2 and method for producing soluble bmp-2 using the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHOI ET AL.: "Protein Solubility and Folding Enhancement by Interaction with RNA", PLOS ONE, vol. 3, no. 7, 16 July 2008 (2008-07-16), XP055106439 *

Also Published As

Publication number Publication date
WO2017160124A2 (en) 2017-09-21

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