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WO2016110838A1 - Assemblages d'adaptateur de flacon double avec adaptateur de flacon de médicament à libération rapide garantissant une utilisation correcte - Google Patents

Assemblages d'adaptateur de flacon double avec adaptateur de flacon de médicament à libération rapide garantissant une utilisation correcte Download PDF

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Publication number
WO2016110838A1
WO2016110838A1 PCT/IL2016/050002 IL2016050002W WO2016110838A1 WO 2016110838 A1 WO2016110838 A1 WO 2016110838A1 IL 2016050002 W IL2016050002 W IL 2016050002W WO 2016110838 A1 WO2016110838 A1 WO 2016110838A1
Authority
WO
WIPO (PCT)
Prior art keywords
liquid
vial
drug
vial adapter
drug vial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IL2016/050002
Other languages
English (en)
Inventor
Uri David
Mordechai BUKHMAN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medimop Medical Projects Ltd
Original Assignee
Medimop Medical Projects Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimop Medical Projects Ltd filed Critical Medimop Medical Projects Ltd
Priority to EP16702453.8A priority Critical patent/EP3217944B1/fr
Priority to US15/541,242 priority patent/US10285907B2/en
Priority to JP2017534927A priority patent/JP6358724B2/ja
Priority to BR112017013534-5A priority patent/BR112017013534B1/pt
Priority to CN201680003972.3A priority patent/CN108601706B/zh
Publication of WO2016110838A1 publication Critical patent/WO2016110838A1/fr
Priority to IL253027A priority patent/IL253027B/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/2013—Piercing means having two piercing ends
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2055—Connecting means having gripping means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture

Definitions

  • the invention relates to dual vial adapter assemblages for use with a drug vial containing a medicament and a liquid vial containing liquid contents for forming a liquid drug from the medicament in the drug vial.
  • Transfer Device discloses a dual vial adapter assemblage hereinafter referred to as the Zinger assemblage for use with a drug vial containing a medicament and a liquid vial containing liquid contents for forming a liquid drug from the medicament in the drug vial.
  • the liquid contents can be diluent only or include an active component.
  • the Zinger assemblage is commercially available from West Pharmaceutical Services, Inc., Exton, USA under the registered trademark MIX2VIAL.
  • the Zinger assemblage includes a drug vial adapter for telescopic mounting on a drug vial and a liquid vial adapter for telescopic mounting on a liquid vial.
  • the drug vial adapter has an integral drug vial stopper puncturing cannula for puncturing a drug vial stopper and a female connector in flow communication therewith.
  • the liquid vial adapter has an integral liquid vial stopper puncturing cannula and a male connector in flow communication therewith.
  • the female connector is preferably a Luer female connector and the male connector is preferably a Luer lock connector for an initial sealed releasable inter-engagement on the Luer female connector.
  • the Zinger assemblage is designed to be employed for use with a drug vial under negative pressure for drawing liquid contents from a liquid vial in an initial sealed inter-engagement of the drug vial adapter and the liquid vial adapter. Accordingly, the Zinger assemblage is necessarily initially telescopically mounted on a liquid vial and on inversion subsequently telescopically mounted on a negative pressure drug vial. Pursuant to forming a liquid drug in the drug vial and detachment of the liquid vial adapter from the drug vial adapter, the entire liquid drug contents are typically completely aspirated into an initially empty needleless syringe for administration purposes.
  • the drug vial adapter includes a female connector and an oppositely directed drug vial adapter sleeve in flow communication therewith.
  • the Denenburg assemblage employs gravitational flow from a liquid vial to a drug vial and therefore requires an initial telescopic mounting on a drug vial and a subsequent telescopic mounting on a liquid vial to avoid spillage from the liquid vial.
  • US Patent No. 8,752,598 Figures 10A to 10G show the use of the Denenburg assemblage for forming liquid drug contents sufficient for aspiration of several liquid drug dosages for staggered administration to a patient.
  • Both the Zinger assemblage and particularly the Denenburg assemblage because of its intended use for forming larger liquid drug volumes can be optionally employed for an administration protocol to a patient including: First, initial aspiration of some liquid drug contents from a drug vial to an initially empty needleless syringe for immediate administration to a patient, thereby leaving a liquid drug remainder in the drug vial. And second, subsequent administration of the liquid drug remainder by removal of the drug vial adapter from the drug vial to expose its drug vial stopper and forced insertion of an infusion set's IV spike through the drug vial stopper for prolonged gravitational infusion flow to the patient.
  • the present invention is directed towards dual vial adapter assemblages similar to hitherto described Zinger assemblage and Denenburg assemblage.
  • the dual vial adapter assemblages include a quick release drug vial adapter with a snap fit flex member pair for telescopic snap fit mounting on a drug vial and an upright finger grip extension pair oppositely extending to their snap fit flex member pair for manually urging inwards towards one another for outwardly flexing their snap fit flex member pair for releasing the quick release drug vial adapter from a drug vial.
  • the quick release drug vial adapter ensures correct usage of a dual vial adapter assemblage by preventing immediate removal of a drug vial adapter from a drug vial after forming liquid drug contents therein, thereby assisting a healthcare provider to follow an administration protocol requiring an initial aspiration of some liquid drug for immediate administration to a patient to leave a liquid drug remainder for subsequent infusion to the patient.
  • Dual vial adapter assemblages of the present invention can be implemented as follows: First, similar to hitherto mentioned US Patent No. 8,752,598 to Denenburg et al. Second, similar to US Patent No. 6,558,365 to Zinger et al. And third, similar to US Patent No. 6,558,365 to Zinger et al. but with a drug vial adapter having an integral dual lumen drug vial stopper puncturing cannula and a liquid vial adapter having an integral dual lumen liquid vial stopper puncturing cannula in initial flow communication with the integral dual lumen drug vial stopper puncturing cannula for enabling initial gravitational flow of liquid contents from a liquid vial to a drug vial.
  • a drug vial adapter having an integral dual lumen drug vial stopper puncturing cannula
  • a liquid vial adapter having an integral dual lumen liquid vial stopper puncturing cannula in initial flow communication with the integral dual lumen drug vial stopper puncturing cannula for
  • Fig. 1 is a pictorial view of an administration set including a needleless syringe, a drug vial, a liquid vial, an infusion set and a first embodiment of a dual vial adapter assemblage in accordance with the present invention
  • Fig. 2 is a perspective view of the Figure 1 dual vial adapter assemblage including a quick release drug vial adapter;
  • Fig. 3 is a perspective view of a dissembled Figure 1 dual vial adapter assemblage
  • Fig. 4 is a longitudinal cross section of the Figure 1 dual vial adapter assemblage along line 4-4 in Figure 2;
  • Fig. 5 is a perspective view showing manual operation of the Figure 2 quick release drug vial adapter
  • Figs. 6A to 6C show use of the Figure 1 dual vial adapter assemblage for administration of a liquid drug contained in a drug vial;
  • Fig. 7 is a perspective view of a second embodiment of a dual vial adapter assemblage including a quick release drug vial adapter in accordance with the present invention
  • Fig. 8 is a longitudinal cross section of the Figure 7 dual vial adapter assemblage along line 8-8 in Figure 7;
  • Fig. 9 is a dissembled view of the Figure 7 dual vial adapter assemblage
  • Fig. 10 is a perspective view of a third embodiment of a dual vial adapter assemblage including a quick release drug vial adapter in accordance with the present invention
  • Fig. 11 is a longitudinal cross section of the Figure 10 dual vial adapter assemblage along line 11-11 in Figure 10;
  • Fig. 12 is a dissembled view of the Figure 10 dual vial adapter assemblage.
  • Figure 1 shows an administration set 10 including an initially empty needleless syringe 10, a drug vial 20, a liquid vial 30, and an infusion set 40, and a dual vial adapter assemblage 100.
  • the needleless syringe 10 includes a barrel 11 with a plunger 12 and a male Luer lock connector 13.
  • the syringe 10 can be formed with other types of male connectors.
  • the drug vial 20 has a longitudinal drug vial axis 20 A and includes an open topped drug vial bottle 21 having a drug vial rim 22 and a narrow diameter drug vial neck 23.
  • the drug vial 20 is sealed by a drug vial stopper 24.
  • the drug vial stopper 24 is capped by a typically aluminum seal 26.
  • the drug vial 20 includes a medicament 27 in the form of a powder, solid or liquid.
  • the liquid vial 30 has a longitudinal liquid vial axis 30A and includes an open topped liquid vial bottle 31 having a liquid vial rim 32 and a narrow diameter liquid vial neck 33.
  • the drug vial 30 is sealed by a liquid vial stopper 34.
  • the liquid vial stopper 34 is capped by a typically aluminum seal 36.
  • the liquid vial 30 includes liquid contents 37 in the form of diluent only or an active component.
  • the infusion set 40 includes an IV spike 41, first tubing 42, a clamp 43, a drip chamber 44, second tubing 46, a roller clamp 47, a male Luer connector 48, and a Luer shield 49.
  • the dual vial adapter assemblage 100 includes a quick release drug vial adapter 110 and a liquid vial adapter 130 in initial sealed releasable inter- engagement.
  • the drug vial adapter 110 has a longitudinal drug vial adapter centerline 111 and a transverse drug vial adapter top wall 112 with an upright female connector 113 and an opposite downward depending drug vial adapter skirt 114 for telescopic snap fit mounting on the drug vial 20.
  • the upright female connector 113 can be a female Luer connector, and the like.
  • the downward depending drug vial adapter skirt 114 includes an opposite snap fit flex member pair 116 resiliently pivotal at their juncture with the drug vial adapter top wall 112.
  • the snap fit flex member pair 116 is formed with an inward directed protrusion pair 117 for snap fit under the drug vial rim 22 on telescopic snap fit mounting the drug vial adapter 110 on the drug vial 20.
  • the downward depending drug vial adapter skirt 114 includes an additional opposite flex member pair 118 primarily employed for guidance purposes during the telescopic snap fit mounting and therefore formed with minor or without any inward directed protrusions.
  • the drug vial adapter 110 has a downward depending sleeve 119 in flow communication with the upright female connector 113 and oppositely directed thereto.
  • the drug vial adapter 110 has a manually operable quick release arrangement 121 for selectively releasing the drug vial adapter skirt 114 from the drug vial 20, thereby exposing the drug vial stopper 24.
  • the liquid vial adapter 130 has a longitudinal liquid vial adapter centerline 131 co-axial with the longitudinal drug vial adapter centerline 111 on in its initial sealed releasable inter-engagement with the drug vial adapter 110.
  • the liquid vial adapter 130 includes a transverse liquid vial adapter top wall 133 and a liquid vial adapter skirt 134 for telescopic snap fit mounting on the liquid vial 30.
  • the liquid vial adapter skirt 134 can optionally telescopically mount on the liquid vial 30 without snap fit.
  • the liquid vial adapter 130 includes a dual ended dual lumen spike 136 including a liquid vial stopper puncturing cannula 137 for puncturing the liquid vial stopper 34 on telescopic snap mounting the liquid vial adapter 130 on the liquid vial 30 and a drug vial stopper puncturing cannula 138 oppositely directed to the liquid vial stopper puncturing cannula 137 along the longitudinal liquid vial adapter centerline 131 for puncturing the drug vial stopper 24 on mounting the drug vial adapter 110 on the drug vial 20 in the assembled state of the dual vial adapter assemblage 100.
  • the drug vial stopper puncturing cannula 138 is encircled by the downward depending sleeve 119 in the initial sealed releasable inter-engagement of the drug vial adapter 110 and the liquid vial adapter 130.
  • the liquid vial adapter 130 includes a male lock connector 139 for releasable engaging the female connector 113.
  • the male lock connector 139 is preferably a male Luer lock.
  • the dual ended dual lumen spike 136 includes a liquid transfer lumen 141 and an air transfer lumen 142.
  • the quick release arrangement 121 is constituted by a pair of opposite upright finger grip extensions 122 oppositely extending to the snap fit flex member pair 116 relative to the drug vial adapter top surface 112.
  • the finger grip extensions 122 are in the form of an inverted U- shape frame 123 each including a pair of opposite upright leg members 124 and a cross member 126 extending therebetween.
  • the U-shape frame 123 reduces the manual force required to be applied to inwardly urge the finger grip extensions 122 toward one another.
  • the cross members 126 face the liquid vial adapter skirt 134 and are sufficiently close thereto such that the liquid vial adapter skirt 134 prevents manual inward urging of the finger grip extensions 122 toward one another to pivot the snap fit flex member pair 116.
  • the use of the dual vial adapter assemblage 100 is the same as the aforementioned US Patent No. 8,752,598 Figures 10A to 10G for preparing liquid drug contents in the drug vial 20, detaching the liquid vial adapter 130 from the drug vial adapter 110 and attaching the needleless syringe 10 for aspirating some liquid drug for administration purposes to leave a liquid drug remainder in the drug vial (see Figure 6A).
  • Use of the dual vial adapter assemblage 100 additionally includes the step of manual operation of the quick release arrangement 121 to facilitate detaching the drug vial adapter 110 from the drug vial 20 to expose its drug vial stopper 24 (see Figure 6B) and insertion of an infusion set's IV spike 41 through the drug vial stopper 24 for gravitational infusion of the liquid drug remainder to a patient (see Figure 6C).
  • Figures 7 to 9 show a dual vial adapter assemblage 200 similar in construction and operation as the hitherto described US Patent No. 6,558,365 to Zinger et al.
  • the dual vial adapter assemblage 200 includes a liquid vial adapter 201 having an integral single lumen liquid vial stopper puncturing cannula 202 and a quick release drug vial adapter 203 having an integral single lumen drug vial stopper puncturing cannula 204 in flow communication with the liquid vial stopper puncturing cannula 202.
  • FIGS 10 to 12 show a dual vial adapter assemblage 300 similar in construction and operation as the hitherto described US Patent No. 6,558,365 to Zinger et al.
  • the dual vial adapter assemblage 300 includes a liquid vial adapter 301 having an integral dual lumen liquid vial stopper puncturing cannula 302 and a quick release drug vial adapter 303 having an integral dual lumen drug vial stopper puncturing cannula 304 in aligned flow communication with the liquid vial stopper puncturing cannula 302 to form an air transfer lumen and a parallel liquid transfer lumen. While particular embodiments of the present invention are illustrated and described, it would be obvious to those skilled in the art that various other changes and modifications can be made without departing from the spirit and scope of the invention.

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Mechanical Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La présente invention concerne des assemblages d'adaptateur de flacon double similaires aux Brevets US N° 6 558 365, Zinger et al, et US Patent N° 8 752 598, Denenburg et al, et comprenant un adaptateur de flacon de médicament à libération rapide avec une paire d'extensions de préhension de doigt droites pour une poussée manuelle de l'intérieur, l'une vers l'autre, afin de permettre la libération depuis un flacon de médicament. L'adaptateur de flacon de médicament à libération rapide garantit l'utilisation correcte d'un assemblage d'adaptateur de flacon double en empêchant le retrait immédiat d'un adaptateur de flacon de médicament à partir d'un flacon de médicament après la formation d'un médicament liquide à l'intérieur, ce qui permet d'aider un prestataire de soins de santé à suivre un protocole d'administration nécessitant une aspiration initiale de certains contenus de médicament liquide pour une administration immédiate à un patient avant une perfusion subséquente du reste de médicament liquide.
PCT/IL2016/050002 2015-01-05 2016-01-03 Assemblages d'adaptateur de flacon double avec adaptateur de flacon de médicament à libération rapide garantissant une utilisation correcte Ceased WO2016110838A1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP16702453.8A EP3217944B1 (fr) 2015-01-05 2016-01-03 Assemblages d'adaptateur de flacon double avec adaptateur de flacon de médicament à libération rapide garantissant une utilisation correcte
US15/541,242 US10285907B2 (en) 2015-01-05 2016-01-03 Dual vial adapter assemblages with quick release drug vial adapter for ensuring correct usage
JP2017534927A JP6358724B2 (ja) 2015-01-05 2016-01-03 正確な使用を確保するための簡易着脱式薬瓶アダプタを有するデュアルバイアルアダプタアセンブリ
BR112017013534-5A BR112017013534B1 (pt) 2015-01-05 2016-01-03 Montagem do adaptador de frasco duplo para uso com um frasco de medicamento e um frasco de líquido
CN201680003972.3A CN108601706B (zh) 2015-01-05 2016-01-03 具有用于保证正确使用的快速释放药瓶转接器的药瓶转接器组件
IL253027A IL253027B (en) 2015-01-05 2017-06-19 Systems with two vial adapters include a quick-release vial adapter to ensure correct use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL236586 2015-01-05
IL23658615 2015-01-05

Publications (1)

Publication Number Publication Date
WO2016110838A1 true WO2016110838A1 (fr) 2016-07-14

Family

ID=55273309

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2016/050002 Ceased WO2016110838A1 (fr) 2015-01-05 2016-01-03 Assemblages d'adaptateur de flacon double avec adaptateur de flacon de médicament à libération rapide garantissant une utilisation correcte

Country Status (7)

Country Link
US (1) US10285907B2 (fr)
EP (1) EP3217944B1 (fr)
JP (1) JP6358724B2 (fr)
CN (1) CN108601706B (fr)
BR (1) BR112017013534B1 (fr)
IL (1) IL253027B (fr)
WO (1) WO2016110838A1 (fr)

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WO2019064296A1 (fr) * 2017-09-29 2019-04-04 West Pharma. Services Il, Ltd Assemblages d'adaptateur pour flacon double comprenant des adaptateurs pour flacons femelles à évent doubles
US10945921B2 (en) 2017-03-29 2021-03-16 West Pharma. Services IL, Ltd. User actuated liquid drug transfer devices for use in ready-to-use (RTU) liquid drug transfer assemblages
USD917693S1 (en) 2018-07-06 2021-04-27 West Pharma. Services IL, Ltd. Medication mixing apparatus
WO2021216821A1 (fr) * 2020-04-24 2021-10-28 West Pharmaceutical Services, Inc. Systèmes de confinement
US11786443B2 (en) 2016-12-06 2023-10-17 West Pharma. Services IL, Ltd. Liquid transfer device with integral telescopic vial adapter for use with infusion liquid container and discrete injection vial

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CA3068441C (fr) 2009-07-29 2024-01-09 Icu Medical, Inc. Dispositifs de transfert de fluides et procedes d'utilisation
KR102481494B1 (ko) 2011-12-22 2022-12-26 아이씨유 메디칼 인코퍼레이티드 의료용 유체 전달 시스템, 유체 전달 방법, 전자 의료용 유체 전달 시스템, 및 전자 의료용 유체 전달 시스템 이용 방법
CA2931195C (fr) 2013-11-25 2019-09-24 Icu Medical, Inc. Procedes et systeme pour remplir des sacs pour perfusion intraveineuse d'un fluide therapeutique
EP4534065A3 (fr) 2015-12-04 2025-06-04 ICU Medical, Inc. Systèmes, procédés et composants pour le transfert de fluides médicaux
USD851745S1 (en) 2016-07-19 2019-06-18 Icu Medical, Inc. Medical fluid transfer system
JP7046051B2 (ja) 2016-07-25 2022-04-01 アイシーユー・メディカル・インコーポレーテッド 医療用流体移送モジュールおよびシステムの中の空気バブルをトラップするためのシステムおよびコンポーネント
AU2017317170B2 (en) 2016-08-22 2019-09-19 Eli Lilly And Company Secured medication transfer system
USD907193S1 (en) * 2018-02-21 2021-01-05 Eli Lilly And Company Secured medication transfer set
GB2575304B (en) * 2018-07-05 2022-05-18 Owen Mumford Ltd Medicament packaging arrangements
DE102019121915A1 (de) * 2019-05-29 2020-12-03 Rpc Formatec Gmbh Überleitungskanüle
CN110841140A (zh) * 2019-11-06 2020-02-28 北京伏尔特技术有限公司 一种带穿刺器和避光延长管的无针接头
US11590057B2 (en) 2020-04-03 2023-02-28 Icu Medical, Inc. Systems, methods, and components for transferring medical fluids
JP2023546374A (ja) 2020-10-09 2023-11-02 アイシーユー・メディカル・インコーポレーテッド 流体移送デバイスおよびそれのための使用の方法
KR102742097B1 (ko) 2020-12-23 2024-12-11 톨마 인터내셔날 리미티드 혼합 주사기 밸브 어셈블리를 위한 시스템 및 방법
USD1010112S1 (en) 2021-07-03 2024-01-02 KAIRISH INNOTECH Private Ltd. Vial adapter with valve
EP4186543B1 (fr) * 2021-11-30 2024-11-20 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Procédé de connexion stérile de deux systèmes fermés par stérilisation à la chaleur
USD1029245S1 (en) 2022-06-22 2024-05-28 Tolmar International Limited Syringe connector

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WO2012150587A1 (fr) * 2011-05-03 2012-11-08 Sabiedriba Ar Ierobezotu Atbildibu "Sdmd" Adaptateur pour flacon
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CN108601706A (zh) 2018-09-28
JP6358724B2 (ja) 2018-07-18
CN108601706B (zh) 2019-06-25
US20170354571A1 (en) 2017-12-14
IL253027A0 (en) 2017-08-31
US10285907B2 (en) 2019-05-14
IL253027B (en) 2021-02-28
BR112017013534B1 (pt) 2021-12-21

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