WO2016197015A1

WO2016197015A1 - Personal care products: kit and methods of use and making

Info

Publication number: WO2016197015A1
Application number: PCT/US2016/035855
Authority: WO
Inventors: Tara NADER
Original assignee: Longeva LLC
Current assignee: Longeva LLC
Priority date: 2015-06-05
Filing date: 2016-06-03
Publication date: 2016-12-08
Anticipated expiration: 2017-12-05

Abstract

The present disclosure provides a composition and method for whitening and restoring natural tooth color, and a composition for application to a skin cell, or a portion of an area of skin. Tooth whitening is a common procedure in general dentistry. It has become desirable for a person's teeth to appear white. Teeth can become stained by food and drink products, including tobacco, vegetables, coffee, tea, and wine. Teeth can also become stained by certain medications. Whitening agents can help remove stains on teeth. Flavorings may be used to add scent, flavor, and color to whitening agents to make the whitening compositions more desirable. A composition of the current disclosure may be applied to a skin cell, or a portion of an area of skin. The composition may decrease the appearance of wrinkles, fine lines, scars, and make a portion of skin appear to be more radiant. A composition of the current disclosure may be used on a skin condition, wherein the skin condition can be cause by a bacterium, a virus, an allergic reaction, or a weakened immune system.

Description

PERSONAL CARE PRODUCTS: KIT AND METHODS OF USE AND MAKING

BACKGROUND OF THE INVENTION

[0001] Tooth whitening is a common procedure in general dentistry. Whitening restores natural tooth color. It has become desirable for a person's teeth to appear white. Teeth can become stained by food and drink products, including tobacco, vegetables, coffee, tea, and wine. Teeth can also become stained by certain medications. Whitening agents can help remove stains on teeth. Flavorings may be used to add scent, flavor, and color to whitening agents to make the whitening compositions more desirable.

[0002] A composition of the current disclosure may be applied to a skin cell, or a portion of an area of skin. The composition may decrease the appearance of wrinkles, fine lines, scars, and make a portion of skin appear to be more radiant. A composition of the current disclosure may be used on a skin condition, wherein the skin condition can be cause by a bacterium, a virus, an allergic reaction, or a weakened immune system.

SUMMARY OF THE INVENTION

[0003] The present disclosure provides a composition and method for whitening and restoring natural tooth color.

[0004] An aspect of the present disclosure provides a composition for whitening a tooth surface comprising a whitening agent, a sugar, a salt, coconut oil, cinnamon oil, clove oil and peppermint oil. In some embodiments, the composition further comprises castor oil. In some embodiments, the composition further comprises squalane oil. In some embodiments, the composition further comprises hemp oil. In some embodiments, the composition further comprises black seed oil. In some embodiments, the composition further comprises black currant oil. In some embodiments, the composition further comprises rose hip oil. In some embodiments, the composition further comprises jojoba oil. In some embodiments, the composition further comprises sesame oil. In some embodiments, the composition further comprises apricot oil. In some embodiments, the composition further comprises avocado oil. In some embodiments, the composition further comprises argan oil. In some embodiments, the composition further comprises almond oil. In some embodiments, the composition further comprises grape seed oil. In some embodiments, the composition further comprises castor oil, squalane oil, hemp oil, black seed oil, black currant oil, rose hip oil, jojoba oil, sesame oil, apricot oil, avocado oil, argan oil, almond oil and grape seed oil.

[0005] In some embodiments, the whitening agent is selected from the group consisting of peroxides, carbonates, bicarbonates, percarbonates, perborates, peroxyacids, and any

combination thereof. In some embodiments, the whitening agent is a carbonate. In some embodiments, the whitening agent is sodium bicarbonate. In some embodiments, the sugar is selected from the group consisting of glucose, fructose, sucrose, erythritol, maltitol, xylitol and any combination thereof. In some embodiments, the sugar is xylitol. In some embodiments, the salt is a sea salt. In some embodiments, the cinnamon oil, the clove oil, and the peppermint oil are in a ratio of about 1 : 1 : 1. In some embodiments, the cinnamon oil, the clove oil, and the peppermint oil are in a ratio of about 1 :2:3. In some embodiments, the cinnamon oil, the clove oil, and the peppermint oil are in a ratio of about 2: 1 :3. In some embodiments, the cinnamon oil, the clove oil, and the peppermint oil are in a ratio of about 3:1:2.

[0006] In some embodiments, the composition further comprises castor oil, squalane oil, hemp oil, black seed oil, black currant oil, rose hip oil, jojoba oil, sesame oil, apricot oil, avocado oil, argan oil, almond oil and grape seed oil, and wherein the cinnamon oil, the clove oil, and the peppermint oil are in a ratio of about 2: 1 :3. In some embodiments, the tooth surface is the tooth surface of a human subject. In some embodiments, the tooth surface is the tooth surface of a denture. In some embodiments, the tooth surface is the tooth surface of a pet. In some

embodiments, the composition is suitable for application by a professional dentist. In some embodiments, the composition is suitable for application by a user. In some embodiments, the composition is applied to at least one tooth in a layer. In some embodiments, the composition is combined with a toothpaste. In some embodiments, the composition is suitable for application on a dental floss. In some embodiments, the composition is suitable for application on a dental tray. In some embodiments, the composition is suitable for application on a disposable plastic strip. In some embodiments, a tooth whitening kit comprises the composition. In some embodiments, a tooth whitening kit comprises the composition and an application tool.

[0007] Another aspect of the present disclosure provides a method for whitening a tooth surface that comprises contacting a tooth surface with a composition, wherein the composition comprises a whitening agent, a sugar, a salt, coconut oil, cinnamon oil, clove oil and peppermint oil. In some embodiments, the composition further comprises castor oil. In some embodiments, the composition further comprises squalane oil. In some embodiments, the composition further comprises hemp oil. In some embodiments, the composition further comprises black seed oil. In some embodiments, the composition further comprises black currant oil. In some embodiments, the composition further comprises rose hip oil. In some embodiments, the composition further comprises jojoba oil. In some embodiments, the composition further comprises sesame oil. In some embodiments, the composition further comprises apricot oil. In some embodiments, the composition further comprises avocado oil. In some embodiments, the composition further comprises argan oil. In some embodiments, the composition further comprises almond oil. In some embodiments, the composition further comprises grape seed oil. In some embodiments, the composition further comprises castor oil, squalane oil, hemp oil, black seed oil, black currant oil, rose hip oil, jojoba oil, sesame oil, apricot oil, avocado oil, argan oil, almond oil and grape seed oil.

[0008] In some embodiments, the whitening agent is selected from the group consisting of peroxides, carbonates, bicarbonates, percarbonates, perborates, peroxyacids, and any

combination thereof. In some embodiments, the whitening agent is a carbonate. In some embodiments, the whitening agent is sodium bicarbonate. In some embodiments, the sugar is selected from the group consisting of glucose, fructose, sucrose, erythritol, maltitol, xylitol and any combination thereof. In some embodiments, the sugar is xylitol. In some embodiments, the salt is a sea salt. In some embodiments, the cinnamon oil, the clove oil, and the peppermint oil are in a ratio of about 1 : 1 : 1. In some embodiments, the cinnamon oil, the clove oil, and the peppermint oil are in a ratio of about 1 :2:3. In some embodiments, the cinnamon oil, the clove oil, and the peppermint oil are in a ratio of about 2: 1 :3. In some embodiments, the cinnamon oil, the clove oil, and the peppermint oil are in a ratio of about 3 : 1 :2. In some embodiments, the composition further comprises castor oil, squalane oil, hemp oil, black seed oil, black currant oil, rose hip oil, jojoba oil, sesame oil, apricot oil, avocado oil, argan oil, almond oil and grape seed oil, and wherein the cinnamon oil, the clove oil, and the peppermint oil are in a ratio of about 2: 1 :3. In some embodiments, the tooth surface is the tooth surface of a human subject.

[0009] In some embodiments, the tooth surface is the tooth surface of a denture. In some embodiments, the tooth surface is the tooth surface of a pet. In some embodiments, application of the composition is by a professional dentist. In some embodiments, application of the

composition is by a user. In some embodiments, purchasing is from a professional dentist. In some embodiments, purchasing is over the counter. In some embodiments, application of the composition is to at least one tooth in a layer. In some embodiments, applying the composition to a tooth surface is with a toothbrush. [0010] In one aspect, the current disclosure provides a composition comprising: at least one plant, extract thereof, oil thereof, or a part thereof; i) at least one molecule comprising one alcohol functional group and at least 8 carbon atoms, or a salt thereof; or ii) at least one molecule comprising at least two alcohol functional groups and 2 to 8 carbons, or a salt thereof; or any combination thereof; at least one vitamin, or a salt thereof; and at least one molecule comprising an oxo group, an acidic group, and at least 4 carbons, ester thereof, salt thereof, or any

combination thereof; wherein the composition is topical composition. In some embodiments, the at least one plant, extract thereof, oil thereof, is a plant. In some embodiments, the plant is selected from the group consisting of aloe vera, green tea, green tea extract, flaxseed, chamomile, lavender, white tea, and saberry. In some embodiments, the composition comprises at least two of the at least one plant, extract thereof, oil thereof, or part thereof. In some embodiments, the composition comprises at least three of the at least one plant, extract thereof, oil thereof, or part thereof.

[0011] In some embodiments, the composition comprises at least 2 volume % of the at least one molecule comprising one alcohol functional group and at least 8 carbons, or a salt thereof; or at least one molecule comprising at least two alcohol functional groups and 2 to 8 carbons, or a salt thereof, wherein the volume % is based on a total volume % of the composition. In some embodiments, the at least one alcohol functional group and at least 8 carbons, or a salt thereof; or at least one molecule comprising at least two alcohol functional groups and 2 to 8 carbons, or a salt thereof. In some embodiments, the composition comprises at least 0.5 volume % of the at least one molecule comprising an oxo group, an acidic group, and at least 4 carbons, ester thereof, salt thereof, or any combination thereof, wherein the volume % is based on a total volume % of the composition.

[0012] In some embodiments, the composition comprises fragrance citrus punch, fragrance clean linen, fragrance coconut, fragrance coconut lime verbena, fragrance coral reef, fragrance lemon verbena, fragrance mandarin-berry, fragrance mangosteen, fragrance neroli, fragrance peppermint oil, fragrance pineapple lily, fragrance sweet orange essential oil, fragrance tea tree essential oil, fragrance vanilla grapefruit, fragrance white peach & ginger, or fragrance white tea.

[0013] In one aspect, the current disclosure provides a method for treatment of a skin condition comprising contacting of a composition of the current disclosure to a subject in need thereof. In some embodiments, the skin cell, an area of skin around the skin cell, or both, is first washed and dried before the contact. In some embodiments, the skin cell is a skin cell of the face, neck, or hands. In some embodiments, the skin cell is a skin cell of the face, abdomen, thighs, buttocks, or arms. In some embodiments, the method further comprises application of an adhesive bandage to the area of skin after the contact. In some embodiments, the composition is contacted for a period of time of at least 1 second. In some embodiments, the composition is packaged into a container selected from the group consisting of a tube, ajar, and a vial. In some embodiments, the tube contains information describing directions for use.

BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 diagrams a schematic of an example of a tooth whitening system. A tooth surface 100 can undergo a contact step 105 with a whitening composition, thereby yielding a whitened tooth surface 110.

DETAILED DESCRIPTION OF THE INVENTION

[0015] The present application relates to compositions to whiten a tooth surface and compositions for application to a skin cell.

[0016] As will be apparent to those of skill in the art upon reading this disclosure, each of the individual examples described and illustrated herein has discrete components and features which may be readily separated from or combined with the features of any of the other several examples without departing from the scope or spirit of the present disclosure. Any recited method can be carried out in the order of events recited or in any other order which is logically possible.

[0017] Before the present methods and compositions are described, it is to be understood that this disclosure is not limited to particular method or composition described, as such may, of course, vary. It is also to be understood that the terminology used herein is for the purpose of describing particular examples only, and is not intended to be limiting, since the scope of the present disclosure will be limited only by the appended claims.

[0018] Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this disclosure belongs. Although any methods and materials similar or equivalent to those described herein can be used in the practice or testing of the present disclosure, some potential and preferred methods and materials are now described. [0019] Where a range of values is provided, it is understood that each intervening value, to the tenth of the unit of the lower limit unless the context clearly dictates otherwise, between the upper and lower limits of that range is also specifically disclosed. Each smaller range between any stated value or intervening value in a stated range and any other stated or intervening value in that stated range is encompassed within the disclosure. The upper and lower limits of these smaller ranges may independently be included or excluded in the range, and each range where either, neither or both limits are included in the smaller ranges is also encompassed within the disclosure, subject to any specifically excluded limit in the stated range. Where the stated range includes one or both of the limits, ranges excluding either or both of those included limits are also included in the disclosure.

[0020] Unless otherwise specified, all percentages and amounts expressed herein and elsewhere in the specification should be understood to refer to percentages by weight. The amounts given are based on the active weight of the material. The recitation of a specific value herein is intended to denote that value, plus or minus a degree of variability to account for errors in measurements. For example, an amount of 10% may include 9.5% or 10.5%, given the degree of error in measurement that will be appreciated and understood by those having ordinary skill in the art.

[0021] It must be noted that as used herein and in the appended claims, the singular forms "a", "an", and "the" include plural referents unless the context clearly dictates otherwise.

[0022] Unless specifically stated or obvious from context, as used herein, the term "about" in reference to a number or range of numbers is understood to mean the stated number and numbers +/- 10% thereof, or 10% below the lower listed limit and 10% above the higher listed limit for the values listed for a range.

[0023] The term "pharmaceutically acceptable salt" or "salt" refers to salts derived from a variety of organic and inorganic counter ions known in the art. Pharmaceutically acceptable acid addition salts can be formed with inorganic acids and organic acids. Inorganic acids from which salts can be derived include, for example, hydrochloric acid, hydrobromic acid, sulfuric acid, nitric acid, phosphoric acid, and the like. Organic acids from which salts can be derived include, for example, acetic acid, propionic acid, glycolic acid, pyruvic acid, oxalic acid, maleic acid, malonic acid, succinic acid, fumaric acid, tartaric acid, citric acid, benzoic acid, cinnamic acid, mandelic acid, methanesulfonic acid, ethanesulfonic acid, p toluenesulfonic acid, salicylic acid, and the like. Pharmaceutically acceptable base addition salts can be formed with inorganic and organic bases. Inorganic bases from which salts can be derived include, for example, sodium, potassium, lithium, ammonium, calcium, magnesium, iron, zinc, copper, manganese, aluminum, and the like. Organic bases from which salts can be derived include, for example, primary, secondary, and tertiary amines, substituted amines including naturally occurring substituted amines, cyclic amines, basic ion exchange resins, and the like, specifically such as

isopropylamine, trimethylamine, diethylamine, triethylamine, tripropylamine, and ethanolamine. In some embodiments, the pharmaceutically acceptable base addition salt is chosen from ammonium, potassium, sodium, calcium, and magnesium salts.

[0024] The oral care compositions of the various embodiments can be in the form of a paste, gel, or liquid formulation. The composition may be in any desired form, such as a homogeneous mix, deep striped, surface striped, multi-layered, having a gel surround the paste, or any combinations thereof.

[0025] In some aspects, the composition comprises an oil. The oil may be a plant oil, an animal oil, or a synthetic oil. The plant oil may be extracted or pressed from a plant, the seed of a plant, or a fruit. Some non-limiting examples of plant oils are agar oil, almond oil, ajwain oil, angelica root oil, anise oil, apricot oil, argan oil, avocado oil, balsam of Peru, basil oil, bay oil, beech nut oil, bergamot oil, black currant oil, black seed oil, black pepper oil, buchu oil, birch oil, cannabis flower essential oil, caraway oil, cardamom seed oil, carrot seed oil, cashew oil, castor oil, cedarwood oil, chamomile oil, coconut oil, corn oil, cotton seed oil, davana oil, dill oil, eucalyptus oil, evening primrose oil, fennel seed oil, flaxseed oil, frankincense oil, geranium oil, ginger oil, grapefruit oil, grapefruit seed oil, grape seed oil, jenna oil, hazelnut oil, hemp oil, horseradish oil, jasmine oil, jojoba oil, juniper berry oil, lavender oil, lemon oil, mentha arvensis oil, mongongo nut oil, moringa oil, mustard oil, neem oil, olive oil, orange oil, oregano oil, orris oil, palm oil, parsley oil, patchouli oil, peanut oil, pecan oil, perilla essential oil, peppermint oil, pine oil, pine nut oil, pumpkin seed oil, rapeseed oil, rice bran oil, rose oil, rose hip oil, rosemary oil, rosewood oil, safflower oil, sage oil, sandalwood oil, sassafras oil, sesame oil, soybean oil, spearmint oil, squalane oil, star anise oil, sunflower oil, tarragon oil, tea tree oil, thyme oil, vanilla oil, walnut oil, watermelon seed oil, or any combinations thereof.

[0026] Some non-limiting examples of an animal oil include cow oil, pig oil, horse oil, sheep oil, deer oil, goat oil, or any combinations thereof.

[0027] Non-limiting examples of plant derivatives include cocoa butter, cocoa seed butter, aloe vera, aloe vera gel, green tea, green tea extract, flaxseed, chamomile, chamomile extract, chamomile flower oil, calendula officinalis flower, calendula officinalis flower extract, tamanu oil, lavender, matricaria flower, white tea, arnica montana flower, aloe barbadensis leaf, borage oil, soy, soy protein, hydrolyzed soy protein, aloe barbadensis leaf juice, carrot seed, saberry, saberry extract, lemon peel extract, cucumber, and cucumber extract; and extracts, oils, juice, stems, leaves, flowers, and roots of the aforementioned plants.

[0028] Vitamins may be added to a composition of the current disclosure. Non-limiting examples of vitamins include vitamin A, vitamin B, vitamin B3, vitamin B5, vitamin BIO, vitamin C, ascorbic acid, ascorbyl palmitate, magnesium ascorbyl phosphate, sodium ascorbyl phosphate, tetrahexyldecyl ascorbate, vitamin E, tocopherol, tocopheryl acetate,

[0029] In some examples, the oils may be combined to form a mixture of oils. In some examples, the oils may be combined to form a blend of 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 95, or 100 or more oils.

[0030] In one non-limiting example, the composition may comprise cinnamon oil. In another non-limiting example, the composition may comprise clove oil. In another non-limiting example, the composition may comprise peppermint oil. In yet another non-limiting example, the composition may comprise cinnamon oil and clove oil. In another non-limiting example, the composition may comprise cinnamon oil and peppermint oil. In another non-limiting example, the composition may comprise clove oil and peppermint oil. In one non-limiting example, the composition can comprise cinnamon oil, clove oil, and peppermint oil. In another non-limiting example, the composition can comprise coconut oil, cinnamon oil, clove oil, and peppermint oil.

[0031] Some non-limiting examples of synthetic oils include petroleum jelly, isopropyl esters, ethylhexyl esters, propoxylated alcohols, oleic acid esters, polymer oils, or any combinations thereof.

[0032] In some aspects, the composition comprises an alcohol.

[0033] Non-limiting examples of an alcohol include simple alcohols, emulsifying wax, wax, glycerin, ethanol, propanol, 1,2-propanediol, stearyl alcohol, glyceryl stearate, phenoxyethanol, glyceryl monolaurate, resveratrol, phenol, resorcinol, benzyl alcohol, methylhexylglycerin, ethylhexylglycerin, panthenol, cetyl alcohol, haloxyl (fluoxymesterone), butanol, pentanol, hexanol, heptanol, octyl alcohol, triglycerides, and capric triglyceride.

[0034] In some aspects, the composition comprises a sugar. Some non-limiting examples of a sugar include fructose, glucose, galactose, sucrose, lactose, maltose, xylitol, erythritol, arabitol, ribitol, mannitol, glycerol, aspartame, cyclamate, saccharin, sucralose, or any combinations thereof.

[0035] Some non-limiting examples of unrefined sugars include cane juice, molasses, raw sugar, brown sugar, sweet sorghum syrup, maize sugar, agave nectar, maple syrup, palm sugar, sweet beet syrup, sweet cicely root, licorice root, barley malt syrup, brown rice malt syrup, watermelon sugar, pumpkin sugar, date syrup, stevia, honey, or any combinations thereof. In one non-limiting example, the sugar can be aspartame. In another non-limiting example, the sugar can be xylitol. In another non-limiting example, the sugar can be honey. In yet another non- limiting example, the sugar can be brown sugar.

[0036] In some aspects, the composition comprises a salt. Some non-limiting examples of a salt include refined sodium chloride salt, potassium chloride, lithium chloride, calcium chloride, magnesium chloride, sea salt, canning salt, pickling salt, table salt, kosher salt, or any

combinations thereof. In one non-limiting example, the salt can be sea salt. In another non- limiting example, the salt can be potassium chloride. In yet another non-limiting example, the salt can be table salt.

[0037] In some aspects, the composition comprises a whitening agent. Some non-limiting classes of whitening agents are peroxides, carbonates, bicarbonates, percarbonates, perborates, peroxyacids. Some non-limiting examples of a whitening agent are hydrogen peroxide, carbamide peroxide, sodium carbonate, sodium bicarbonate, sodium perborate, perphthalic acid, diperoxycarboxylic acids, 1,12-dodecanedioic peroxy acid, peroxy acetic acid, or any

combinations thereof. In one non-limiting example, the whitening agent can be hydrogen peroxide. In another non-limiting example, the whitening agent can be sodium carbonate. In one non-limiting example, the whitening agent can be sodium bicarbonate.

[0038] The oral care compositions of the present invention may furthermore comprise optional, conventional ingredients such as pharmaceutically acceptable carriers like starch, sucrose, water, or any combinations thereof. Small amounts of surfactants or abraisive materials may also be included. Some non-limiting examples include anionic, nonionic amphoteric surfactants, silicas, aluminas, calcium carbonates, dicalciumphosphates, calcium pyrophosphates hydroxyapatites, trimetaphosphates, insoluble hexametaphosphates, or any combinations thereof.

[0039] In some examples, trace amounts of other additives can be added to the formulation. Non-limiting examples of additives include apple powder, citrus pectins, arabic gum, ascorbic acid, beeswax, betaine hydrochloride, biotin, cetyl alcohol, choline chloride, citric acid, cobalt carbonate, copper sulfate, corn starch, dextrose, folic acid, glycine, lanolin, lemon powder, maltodextrin, manganese sulfate, magnesium chloride, magnesium oxide, malic acid, niacin, pantothenic acid, potassium chloride, potassium sulfate, polysorbate, propylene glycol, purple pigment, riboflavin, sodium citrate, steryl alcohol, vaseline, vitamin A, vitamin B 12, vitamin D, vitamin E, vitamin K, and zinc sulfate. Other non-limiting classes of additives include, for example, thickening agents, humectants, ionic active ingredients, buffering agents, aniicalculus agents, abrasive polishing materials, peroxide sources, alkali metal bicarbonate salts, surfactants, titanium dioxide, coloring agents, flavor systems, sweetening agents, antimicrobial agents, herbal agents, desensitizing agents, stain reducing agents, stabilizing agents, or any combinations thereof,

[0040] In some examples, an ingredient in a composition of the current disclosure is selected from acrylate copolymer, acticaps argireline, acticaps retinol, aha fruit acids, algae extract, algae extract, organic, algae extract & hyaluronate, allantoin, almond oil, aloe vera, aloe vera powder, alpha-arbutin, alpha olefin sulfonate, aluminum chlorohydrate, amodimethicone, argan oil, argireline, arnica extract, avobenzone, avocado butter, avocado oil, bacillus ferment, bamboo extract, baobab oil, baobab protein, hydrolyzed, bees wax, behentrimonium, benzylalcohol, bht, beta glucan, bilberry fruit extract, bismuth oxychloride, C12- 15 alkyl benzoate, camelina oil, candelilla wax, caprylic acid combo, caprylyl glycol, caramel colorant, carnauba wax, carrot cells, castile soap, castor oil, ceramide complex, cetearyl alcohol, cetrimonium chloride, cetyl alcohol, cetyl palmitate, cetyl phosphate, chamomile extract, chaparral extract, cherry kernel oil, citric acid, cocoa butter, organic, cocoa butter wafers deodorized, organic, coco betaine, coco glucose, coconut oil, coenzyme q10, collagen protein, hydrolyzed, colloidal oatmeal, conditioner sd, cucumber fruit extract, cyclo-dimethicone, decyl glucoside sodium lauroyl lactylate, desert fruit blend, dihydroxyacetone, dimethicone 500, dimethicone satin, edelweiss extract, organic, edta, elastin protein, hydrolyzed, erythrulose, eyecomplex 4, eye lash hexa peptide, eye lash penta peptide, flavor creme-de-coco, flavor guava-pineapple, flavor honey-lemon, flavor vanilla, follicle booster, fragrance citrus punch, fragrance clean linen, fragrance coconut, fragrance coconut lime verbena, fragrance coral reef, fragrance lemon verbena, fragrance mandarin-berry, fragrance mangosteen, fragrance neroli, fragrance peppermint oil, fragrance pineapple lily, fragrance sweet orange essential oil, fragrance tea tree essential oil, fragrance vanilla grapefruit, fragrance white peach & ginger, fragrance white tea, gluconolactone, glucose, glycan booster peptide, glycerin, glyceryl oleate, glyceryl stearate, glycolic acid, glycol stearate, glycoproteins, goldenseal extract, grape seed extract, grapeseed oil, green tea butter, green tea eco extract, guar gum, gum arabic, haloxyl, hectorite gel, hemp seed oil, homosalate, honeysuckle blend, horse chestnut extract, hyaluronic acid, iso-dimethicone copolymer, isododecane, isoeicosane, isolanolin, isopropyl myristate, jojoba castor beads exfoliant, jojoba gel, jojoba oil, jojoba pearls, jojoba protein, kakadu plum extract, kaolin, kaolin clay, green, kaolin clay, red, kaolin clay, yellow, keratin protein, hydrolyzed, knotgrass flavonoids, kojic acid, lacto-ceramide, lanolin alcohol, lecithin, licorice extract, lupine protein, macadamia nut oil, magnesium stearate, marrubium extract, mc eye lash serum, meadowfoam seed oil, menthol crystals, mica powder, potassium aluminum silicate, microcrystalline wax, microcrystalline wax pastilles, mineral base, mineral oil, moisture, mulberry root extract, multi herb oily skin, myristic acid, myristyl myristate, natural gel wax, niacinamide, octocrylene, octyldodecanol, cinnamate, orange- lemongrass blend, orange peel butter, oxybenzone, ozokerite wax, palm butter, paraben-du, pearl powder, peppermint oil, petroleum jelly, phenoxyethanol sa, pigment red no. 6, pigment red no. 7, pigment red no. 40, pigment yellow no. 5, polyamide 3, polyethylene, polyglucose, polyglyceryl oleate, polyisobutene 250, polyisobutene 1200, polylactic acid beads, polyquaternium 10, polysorbate 20, polysorbate 60, polysorbate 80, potassium sorbate, propylene glycol,

propyltrimonium, provitamin b5 (d-panthenol), PVP (polyvinylpyrrolidone), red raspberry seed oil, resveratrol powder, rhodiola hairactive, rhubarb root extract, rice bran beads, rice quat, rose hip oil, rosemary leaf extract, rosemary leaf extract, organic, sage extract, salicylic acid, sea fennel extract, seaferment sa, sea kelp extract, sebum, shea nut, silicone gel, silk protein, cocoyl taurate, soapwort extract, sodium gluconate, sodium lauryl sulfate, sorbitan oleate, sorbitan stearate, sorbitol, soy-rice peptides, squalane, stearic acid, stearyl palmitate, sucrose cocoate, sulfosuccinate, sulphur mud, sunflower oil, talc, tapioca starch, tea tree essential oil, teprenone, titanium dioxide, tomato lycopene, resveratrol fluid, triethanolamine, triglyceride, urea, walnut shell powder, watermelon extract, wheat protein, hydrolyzed, white tea extract, willow bark extract, willow bark extract, organic, witch hazel extract, wrinkle blur, xanthan gum, and zinc oxide.

[0041] In some embodiments, a dye may be added to a composition of the current disclosure. Non-limiting examples of dyes include D&C Red Nos. 2, 5, 6, 7, 10, 11, 12, 13, 30, 34, D&C Yellow No. 5, D&C Blue No. 1, a metal oxide, and a metal hydroxide, silicic acid, silicic acid anhydride, magnesium silicate, talc, sericite, mica, kaolin, iron oxide red, clay, bentonite, titanium-coated mica, bismuth oxychloride, zirconium oxide, magnesium oxide, zinc oxide, titanium oxide, aluminium oxide, calcium sulfate, barium sulfate, magnesium sulfate, calcium carbonate, magnesium carbonate, iron oxide, ultramarine blue, chromium oxide, chromium hydroxide, carmine, carbon black, polyamide, polyester, polypropylene, polystyrene,

polyurethane, vinyl resin, urea resin, phenol resin, fluororesin, silicone resin, acrylic resin, melamine resin, epoxy resin, polycarbonate resin, divinyl benzene-styrene copolymer, silk powder, cellulose, CI pigment yellow, and CI pigment orange. [0042] In any composition herein, an ingredient can be individually present in an amount from 0.0001% to 99.9999%, wherein the amount can be based on weight %, volume %, or mole %, based on the total weight %, volume %, or mole % of the composition. In some examples, an ingredient can be present in an amount from 0.001% to 99.99%, 0.1% to 99.9%, 1% to 99%, 5% to 95%, 10% to 90%, 20% to 80%, 30% to 70%, or 50% to 60%, wherein the amount can be based on weight %, volume %, or mole %, based on the total % of the composition.

[0043] In some examples, each ingredient of the composition can have a volume by volume percent equal to or less than about 0.01%, 0.02%, 0.03%, 0.04%, 0.05%, 0.06%, 0.07%, 0.08%, 0.09%, 0.1%, 0.15%, 0.20%, 0.25%, 0.30%, 0.35%, 0.40%, 0.5%, 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 15%, 20%, 25%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 95%, or 100%.

[0044] In some examples, each ingredient of the composition has a volume by volume percent equal to or greater than about 0.01%, 0.02%, 0.03%, 0.04%, 0.05%, 0.06%, 0.07%, 0.08%, 0.09%, 0.1%, 0.15%, 0.20%, 0.25%, 0.30%, 0.35%, 0.40%, 0.5%, 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 15%, 20%, 25%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 95%, or 100%.

[0045] In one non-limiting example, sodium bicarbonate can have a w/w % of about 20-80%, about 40-60%, about 55%, or about 52%. In another non-limiting example, xylitol can have a w/w % of about 10-50%, about 20-30%, or about 25%. In another non-limiting example, sea salt can have a w/w % of about 0.1-5%, or about 1%. In another non-limiting example, coconut oil can have a w/w % of about 5-25%, about 10-15%, or about 13%. In one non-limiting example, cinnamon oil can have a w/w % of about 1-5%, or 3%. In another non-limiting example, clove oil can have a w/w % of about 0.1-5%, or about 1%. In another non-limiting example, peppermint oil can have a w/w % of about 1-5%, or about 3%. In another non-limiting example, squalane oil can have a w/w % of about 0.01-5%, or about 0.1%. In another non-limiting example, hemp oil can have a w/w % of about 0.01-5%, or about 0.1%. In another non-limiting example, black seed oil can have a w/w % of about 0.01-5%, or about 0.1%. In another non-limiting example, black currant oil can have a w/w % of about 0.01-5%,or about 0.1%. In another non-limiting example, rose hip oil can have a w/w % of about 0.01-5%, or about 0.1%. In another non-limiting example, jojoba oil can have a w/w % of about 0.01-5%, or about 0.1%. In another non-limiting example, sesame oil can have a w/w % of about 0.01-5%, or about 0.1%. In another non-limiting example, apricot can have a w/w % of about 0.01-5%, or about 0.1%. In another non-limiting example, avocado oil can have a w/w % of about 0.01-5%,or about 0.1%. In another non-limiting example, argan oil can have a w/w % of about 0.01-5%, orabout 0.1%. In another non-limiting example, almond oil can have a w/w % of about 0.01-5%, orabout 0.1%. In another non-limiting example, grape seed oil can have a w/w % of about 0.01-5%, or about 0.1%.

[0046] In some embodiments, the amount of a compound in a composition is expressed by weight %, wherein the weight % of the compound is based on a total weight % of the

composition.

[0047] In some embodiments, an ingredient can be present in a composition in about 0.1 weight %, 0.2 weight %, 0.3 weight %, 0.4 weight %, 0.5 weight %, 0.6 weight %, 0.7 weight %, 0.8 weight %, 0.9 weight %, 1 weight %, 2 weight %, 3 weight %, 4 weight %, 5 weight %, 6 weight %, 7 weight %, 8 weight %, 9 weight %, 10 weight %, 11 weight %, 12 weight %, 13 weight %, 14 weight %, 15 weight %, 16 weight %, 17 weight %, 18 weight %, 19 weight %, 20 weight %, 21 weight %, 22 weight %, 23 weight %, 24 weight %, 25 weight %, 26 weight %, 27 weight %, 28 weight %, 29 weight %, 30 weight %, 35 weight %, 40 weight %, 50 weight %, 60 weight %, 70 weight %, 80 weight %, 90 weight %, or 95 weight %, wherein the weight % of the compound is based on a total weight % of the composition. In some embodiments, a compound is present in a composition in greater than about 0.1 weight %, 0.2 weight %, 0.3 weight %, 0.4 weight %, 0.5 weight %, 0.6 weight %, 0.7 weight %, 0.8 weight %, 0.9 weight %, 1 weight %, 2 weight %, 3 weight %, 4 weight %, 5 weight %, 6 weight %, 7 weight %, 8 weight %, 9 weight %, 10 weight %, 11 weight %, 12 weight %, 13 weight %, 14 weight %, 15 weight %, 16 weight %, 17 weight %, 18 weight %, 19 weight %, 20 weight %, 21 weight %, 22 weight %, 23 weight %, 24 weight %, 25 weight %, 26 weight %, 27 weight %, 28 weight %, 29 weight %, 30 weight %, 35 weight %, 40 weight %, 50 weight %, 60 weight %, 70 weight %, 80 weight %, 90 weight %, or 95 weight %, wherein the weight % of the compound is based on a total weight % of the composition.

[0048] In some embodiments, an ingredient is present in a composition in a positive amount and less than about 0.1 weight %, 0.2 weight %, 0.3 weight %, 0.4 weight %, 0.5 weight %, 0.6 weight %, 0.7 weight %, 0.8 weight %, 0.9 weight %, 1 weight %, 2 weight %, 3 weight %, 4 weight %, 5 weight %, 6 weight %, 7 weight %, 8 weight %, 9 weight %, 10 weight %, 11 weight %, 12 weight %, 13 weight %, 14 weight %, 15 weight %, 16 weight %, 17 weight %, 18 weight %, 19 weight %, 20 weight %, 21 weight %, 22 weight %, 23 weight %, 24 weight %, 25 weight %, 26 weight %, 27 weight %, 28 weight %, 29 weight %, 30 weight %, 35 weight %, 40 weight %, 50 weight %, 60 weight %, 70 weight %, 80 weight %, 90 weight %, or 95 weight %, wherein the weight % of the compound is based on a total weight % of the composition. [0049] In some embodiments, the amount of a compound in a composition is expressed by a volume %, wherein the volume % of the compound is based on a total volume % of the composition.

[0050] In some embodiments, the amount of a compound in a composition is expressed by a volume %, wherein the volume % of the compound is based on a total volume % of the composition.

[0051] In some embodiments, an ingredient can be present in a composition in about 0.1 volume %, 0.2 volume %, 0.3 volume %, 0.4 volume %, 0.5 volume %, 0.6 volume %, 0.7 volume %, 0.8 volume %, 0.9 volume %, 1 volume %, 2 volume %, 3 volume %, 4 volume %, 5 volume %, 6 volume %, 7 volume %, 8 volume %, 9 volume %, 10 volume %, 11 volume %, 12 volume %, 13 volume %, 14 volume %, 15 volume %, 16 volume %, 17 volume %, 18 volume %, 19 volume %, 20 volume %, 21 volume %, 22 volume %, 23 volume %, 24 volume %, 25 volume %, 26 volume %, 27 volume %, 28 volume %, 29 volume %, 30 volume %, 35 volume %, 40 volume %, 50 volume %, 60 volume %, 70 volume %, 80 volume %, 90 volume %, or 95 volume %, wherein the volume % of the compound is based on a total volume % of the composition.

[0052] In some embodiments, two ingredients in a composition can be expressed by ratio, wherein the ratio is based on weight %. In some embodiments, two ingredients in a composition can be expressed by ratio, wherein the ratio is based on volume %.

[0053] In some examples, any of two ingredients can be in a ratio of about 1:1, 1:2, 1:3, 1 :4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:11, 1:12, 1:13, 1:14, 1:15, 1:16, 1:17, 1:18, 1:19, 1:20, 1:25, 1:30, 1:35, 1:40, 1:45, 1:50, 1:55, 1:60, 1:65, 1:70, 1:75, 1:80, 1:85, 1:90, 1:95, 1:100, 1:150, 1:200, 1:250, 1:300, 1:400, 1:500, 1:600, 1:700, 1:800, 1:900, 1:1000, 1:1500, 1:2000, 1:3000, 1:4000, 1 :5000, 1 :6000, 1 :7000, 1 :8000, 1 :9000, or 1 : 10000, wherein the ratio is based on weight.

[0054] In some examples, any of two ingredients can be in a ratio of about 1:1, 1:2, 1:3, 1 :4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:11, 1:12, 1:13, 1:14, 1:15, 1:16, 1:17, 1:18, 1:19, 1:20, 1:25, 1:30, 1:35, 1:40, 1:45, 1:50, 1:55, 1:60, 1:65, 1:70, 1:75, 1:80, 1:85, 1:90, 1:95, 1:100, 1:150, 1:200, 1:250, 1:300, 1:400, 1:500, 1:600, 1:700, 1:800, 1:900, 1:1000, 1:1500, 1:2000, 1:3000, 1:4000, 1 :5000, 1 :6000, 1 :7000, 1 :8000, 1 :9000, or 1 : 10000, wherein the ratio is based on volume.

[0055] In some examples, any of two ingredients can be in a ratio of about 1:1, 1 :2, 1:3, 1 :4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:11, 1:12, 1:13, 1:14, 1:15, 1:16, 1:17, 1:18, 1:19, 1:20, 1:25, 1:30, 1:35, 1:40, 1:45, 1:50, 1:55, 1:60, 1:65, 1:70, 1:75, 1:80, 1:85, 1:90, 1:95, 1:100, 1:150, 1:200, 1:250, 1:300, 1:400, 1:500, 1:600, 1:700, 1:800, 1:900, 1:1000, 1:1500, 1:2000, 1:3000, 1:4000, 1 :5000, 1 :6000, 1 :7000, 1 :8000, 1 :9000, or 1 : 10000, wherein the ratio is based on moles.

[0056] In one non-limiting example, the composition can comprise sodium bicarbonate and xylitol in a relative ratio of about 2:1. In one non-limiting example, the composition can comprise sodium bicarbonate and xylitol in a relative ratio of about 2.36:1.

[0057] In one non-limiting example, the composition can comprise coconut oil and cinnamon oil in a relative ratio of about 6.4:1. In another non-limiting example, the composition can comprise coconut oil and clove oil in a relative ratio of about 12.8:1. In another non-limiting example, the composition can comprise coconut oil and peppermint oil in a relative ratio of about 3.9:1.

[0058] In one non-limiting example, the composition can comprise cinnamon oil, clove oil, and peppermint oil in a relative ratio of about 1 : 1 : 1. In another non-limiting example, the composition can comprise cinnamon oil, clove oil, and peppermint oil in a relative ratio of about 1:2:3. In yet another non-limiting example, the composition can comprise cinnamon oil, clove oil, and peppermint oil in a relative ratio of about 2: 1 :3. In another non-limiting example, the composition can comprise cinnamon oil, clove oil, and peppermint oil in a relative ratio of about 3:1:2.

[0059] In some examples, the viscosity of the individual ingredients or the final paste composition is about 10, 100, 1000, 2000, 3000, 4000, 5000, 6000, 7000, 8000, 9000, 10,000, 20,000, 30,000, 40,000, 50,000, 60,000, 70,000, 80,000, 90,000, 100,000, 150,000, 200,000, 250,000, 500,000, 750,000, or 1,000,000 cP.

[0060] A user can pay for the composition. The composition can be paid for by cash, credit card, debit card or promotional code. The composition may be available for purchase from a variety of sources. Some non-limiting examples of sources for purchasing the composition are over-the-counter, online, and in specially stores. The composition may be made available by a professional. The composition may be prescribed by a professional.

[0061] Indications

[0062] Compositions of the current disclosure may be contacted with a skin cell. The skin cell may be a human skin cell. The skin cell, area of skin around a skin cell, or both, may be first washed and dried before contact. A skin cell may be a skin cell of the face, neck, hands, abdomen, thighs, buttocks, toes, feet, scalp, knees, or arms.

[0063] Compositions of the current disclosure may be used on an infected skin cell. The infection of the skin cell may be caused by a bacterium, a virus, or a fungus. Bacterial skin infections include, but are not limited to, leprosy, carbuncles, staphylococcus aureus infection, cellulitis, impetigo, boils, pilonidal cyst, abscess, or combinations thereof. Fungal skin infections include, but are not limited to, ringworm, athlete's foot, yeast infection, sporotrichosis, fungal nail infection, or combinations thereof.

[0064] In some embodiments, a composition of the current disclosure is used on a skin condition, wherein the skin condition is rosacea, a wart, a mole, chickenpox, acne, rashes, hives, eczema (atopic, allergic, or nummular dermatitis), skin cancer, rosacea, seborrheic dermatitis (causing cradle cap or dandruff), psoriasis, vitiligo, impetigo, warts, eczema (atopic dermatitis), diaper dermatitis, seborrheic dermatitis (cradle cap), chickenpox, measles, warts, acne, roseola, hives, ringworm, or a rash.

[0065] The cause of a skin condition may be a bacteria, a virus, an allergic reaction, fungus, a parasite, or a microorganism living in the skin, a weakened immune system (with or without coexisting infection), contact with allergens, irritants, or another person's infected skin, diaper rash, dehydration, cold, poor nutrition, side effect of medical procedures, conditions, or medication, such as radiation therapy, pregnancy, diabetes, hypothyroidism, kidney failure, sun, exposure to extreme temperatures, exercise, heat from sunlight, sunburns, anxiety, stress, or a burn.

[0066] In some embodiments, a composition of the current disclosure may be used on a subject with a skin condition as a result of a weakened immune system, side effect of medical procedures, or from a burn. In some embodiments, a composition of the current disclosure may be used on a subject with a skin condition as a result of radiation therapy.

[0067] In some embodiments, a composition of the current disclosure may be used on skin that exhibits a symptom.

[0068] In some embodiments, a composition may contain components that act synergistically, or more than the additive effects of each individual component. In some embodiments, a composition may have a combination index of less than 1, signifying a synergistic effect of the components. The components acting synergistically may be 2 components, 3 components, 4 components, 5 components, 6 components, 7 components, 8 components, 9 components, 10 components, 15 components, 20 components, or more. Synergy within a composition, or between 2 or more components, may be determined by a skin comparison of different parts of skin on one person, 2 people, 3 people, or more. In some cases, components of a composition disclosed herein can be individually applied onto a distinct surface of an area of skin, e.g. arm, leg, torso. The number of components applied may be 2, 3, 4, 5, 6, 7, 8, 9, 10, or more. The distinct surfaces may be compared, and the comparative result may determine the level or amount of synergy between two or more components.

[0069] The ratio of two individual components of a composition disclosed herein that have a synergistic effect may be in a ratio about 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1 :7, 1:8, 1:9, 1:10, 1:11, 1:12, 1:13, 1:14, 1:15, 1:16, 1:17, 1:18, 1:19, 1:20, 1:25, 1:30, 1:35, 1:40, 1:45, 1:50, 1:55, 1:60, 1:65, 1:70, 1:75, 1:80, 1:85, 1:90, 1:95, 1:100, 1:150, 1:200, 1:250, 1:300, 1:400, 1:500, 1:600, 1:700, 1:800, 1:900, 1:1000, 1:1500, 1:2000, 1:3000, 1:4000, 1:5000, 1:6000, 1:7000, 1:8000, 1:9000, or 1 : 10000, wherein the ratio is based on weight %, volume %, or mole %.

[0070] A symptom of a skin condition may be a dry patch of skin, a wart, a bump, a dark spot, a colored speck, coloration of a patch of skin, peeling of skin, soreness of skin, an abnormal skin growth, a rash, an itch, scaly or rough skin, dry, cracked skin, chafing and peeling skin, open sores or lesions, changes in mole color or size, loss of skin pigment, excessive flushing with or without stimulus discolored patches of skin, or any combination thereof.

[0071] In some embodiments, a composition can comprise one or more of the following ingredients: anise seed, amaranth, argan, pomegranate extract, perilla seed extract, black seed, borage, grapeseed extract, sea buckthorne, and gossypium herbaceum.

[0072] In some embodiments, a composition can comprise one or more of the following ingredients: helianthus annuus (sunflower) oil, olea europaea (olive) oil, carrubba efa blend, lebermuth oil blend,tocopheryl acetate (vitamin e), Oenothera biennis (evening primrose) oil, cocos nucifera (coconut) oil, and theobroma cacao (cocoa) seed butter.

[0073] In some embodiments, a composition can comprise one or more of the following ingredients: purified water, emulsifying wax, glycerin, safflower oil, octyl palmitate, glyceryl stearate, stearyl alcohol, glyceryl stearate, phenoxyethanol, glyceryl mono laurate, tocopheryl acetate (vitamin e), magnesium ascorbyl phosphate, squalane, carrubba efa blend lebermuth omni blend, syncoll, saberry, argeiline, coqlO, resveratrol, benzyl alcohol, lecithin, ethylhexylglycerin, stearic acid, panthenol, aloe vera gel, vitamin e, xanthane gum, allantoin, camellia, sinensis (green tea) extract, allantoin, camellia sinensis, green tea extract, flaxseed oil, anthemis, nobilis (chamomile) extract, calendula officinalis flower extract, rosa, canina (rosehip) fruit oil, anthemis, nobilis (chamomile) flower oil calophyllum, tacamahaca (tamanu) oil, and hyaluronic acid.

[0074] In some embodiments, a composition can comprise one or more of the following ingredients: purified water, carthamus tinctorius (safflower) oil, octyl palmitate, glycerin, glyceryl stearate, stearic acid, benzyl alcohol, helianthus annuus (sunflower) oil, caprilic/capric triglyceride, phenoxyethanol, fragrance, glycereth-7 cocoate, carrubba efa blend, lebermuth omni blend, cetyl alcohol, soy lecithin, carbomer, ethylhexylglycerin, panthenol, papain (and) bromelain (and) maltodextrin, mixed tocopherols (vitamin e), allantoin, lavandula angustifolia (lavender) flower/leaf/stem extract (+) chamomile recutita (matricaria) flower extract (+) camellia sinensis (white tea) extract (+), arnica montana flower extract, aloe barbadensis leaf juice, linum usitatissimum (flaxseed) oil, magnesium ascorbyl phosphate, borago officinalis (borage) oil, and rosa canina (rosehip) fruit oil.

[0075] In some embodiments, a composition can comprise one or more of the following ingredients: purified water, sodium cl4-16 olefin sulfonate, cocamidopropyl betaine, glycerin, lebermuth oil blend, hydrolyzed soy protein, panthenol, sodium benzoate, potassium sorbate, ethylhexylglycerin, aloe barbadensis leaf juice (aloe vera gel), and allantoin. in some

embodiments, a composition can comprise one or more of the following ingredients: purified water, sodium cl4-16 olefin sulfonate, cocamidopropyl betaine, glycerin, ethylhexylglycerin, citric acid, carrubba efa blend, lebermuth oil blend, potassium sorbate, panthenol, sodium benzoate, allantoin, magnesium ascorbyl phosphate, sodium pea, disodium cocyl glutamate, and aloe barbadensis leaf juice.

[0076] In some embodiments, a composition can comprise one or more of the following ingredients: purified water, emulsifying wax, glycerin, squalane, magnesium ascorbyl phosphate, tocopheryl acetate (vitamin e), benzyl alcohol, panthenol, glyceryl mono laurate, phenoxyethanol, cetyl alcohol, glyceryl stearate, helianthus annuus (sunflower) oil, mixed tocopherols (vitamin e), amodimethicone, lecithin, algin (sodium alginate), ethylhexylglycerin, carrto seed oil, carrubba efa blend, lebermuth oil blend, emblica extract (saberry), argeriline, syncoll, theobroma cacao (cocoa) seed butter, aloe barbadensis leaf juice, allantoin, borago officinalis (borage) oil, xanthane gum, linum usitatissimum (flaxseed) oil, rosa canina (rosehip) fruit oil, hyaluronic acid, (+) lavandula angustifolia (lavender) flower/leaf/stem extract (+) chamomile recutita (matricaria) flower extract (+) camellia sinensis (white tea) extract (+) arnica montana flower extract, and citrus medica limonum (lemon) peel extract.

[0077] In some embodiments, a composition can comprise one or more of the following ingredients: purified water, zinc oxide, caprilic/capric triglyceride, polyglyceryl-4 isostearate (and) cetyl dimethicone (and) hexyl laurate, glycerin, hydrogenated castor oil, dimethicone, magnesium sulfate, sorbitan sesquioleate, carrubba efa blend, lebermuth oil blend, syncoll, emblica extract (saberry), argeriline, coqlO, resveratrol, phenoxyethanol, and ethylhexylglycerin.

[0078] In some embodiments, a composition can comprise one or more of the following ingredients: helianthus annuus (sunflower) oil, olea europaea (olive) oil, carrubba efa blend, lebermuth oil blend, tocopheryl acetate (vitamin e), Oenothera biennis (evening primrose) oil, cocos nucifera (coconut) oil, shea butter, and theobroma cacao (cocoa) seed butter, in some embodiments, a composition can comprise one or more of the following ingredients: purified water, emulsifying wax, phenoxyethanol, squalane, dipalmitoyl hydroxyproline, carbomer, soy lecithin, saffron extract, gold extract, carruba efa blend, resveratrol, lebermuth oil blend, hyaluronic acid, ethylhexylglycerin, magnesium ascorbyl phosphate, and emblica officinalis extract (saberry).

[0079] In some embodiments, a composition can comprise one or more of the following ingredients: purified water, emulsifying wax, glycerin, carthamus tinctorius (safflower) oil, octyl palmitate, glyceryl stearate, stearyl alcohol, glyceryl stearate, haloxyl, eyeliss, magnesium ascorbyl phosphate, glyceryl mono laurate, tocopheryl acetate (vitamin e), phenoxyethanol, squalane, benzyl alcohol, lecithin, ethylhexylglycerin, stearic acid, mixed tocopherols (vitamin e), xanthane gum, allantoin, camellia sinensis (green tea) extract, borago officinalis (borage) oil, aloe barbadensis leaf juice, rosa canina (rosehip) fruit oil, linum usitatissimum (flaxseed) oil, panthenol, phospholipids superoxide dismutase, citrus medica limonum (lemon) peel extract, and melatonin.

[0080] In some embodiments, a composition can comprise one or more of the following ingredients: purified water, emulsifying wax, glycerin, carthamus tinctorius (safflower) oil, octyl palmitate, glyceryl stearate, stearyl alcohol, glyceryl stearate, haloxyl, eyeliss, magnesium ascorbyl phosphate, glyceryl mono laurate, tocopheryl acetate (vitamin e), phenoxyethanol, squalane, benzyl alcohol, lecithin, ethylhexylglycerin, stearic acid, mixed tocopherols (vitamin e), xanthane gum, allantoin, camellia sinensis (green tea) extract, borago officinalis (borage) oil, aloe barbadensis leaf juice, rosa canina (rosehip) fruit oil, linum usitatissimum (flaxseed) oil, panthenol, phospholipids superoxide dismutase, citrus medica limonum (lemon) peel extract, and melatonin.

[0081] In some embodiments, a composition can comprise one or more of the following ingredients: purified water, glycerin, benzyl alcohol, sorbitan oleate decylglucoside crosspolymer, phenoxyethanol, sodium pea, panthenol, ethylhexylglycerin, aloe barbadensis leaf juice, allantoin, cucumis sativus (cucumber) extract, camellia sinensis (green tea) extract, anthemis nobilis (chamomile) extract, carrubba efa blend, lebermuth oil blend, echinacea purpurea extract, and magnesium ascorbyl phosphate, in some embodiments, a composition can comprise one or more of the following ingredients: purified water, glycerin, benzyl alcohol, sorbitan oleate

decylglucoside crosspolymer, phenoxyethanol, sodium pea, panthenol, ethylhexylglycerin, aloe barbadensis leaf juice, allantoin, cucumis sativus (cucumber) extract, camellia sinensis (green tea) extract, anthemis nobilis (chamomile) extract, carrubba efa blend, lebermuth oil blend, echinacea purpurea extract, and magnesium ascorbyl phosphate.

[0082] In some embodiments, a composition can comprise one or more of the following ingredients: sodium bicarbonate, xylitol, sea salt, coconut oil, cinnamon oil, clove oil, peppermint oil, squalane oil, hemp oil, black seed oil, black current oil, rose hip oil, jojoba oil, sesame oil, apricot oil, avocado oil, argan oil, almond oil, and grape seed oil.

[0083] A composition of the current disclosure may be used as a facial washing cream, facial washing foam, cleansing cream, cleansing milk, cleansing lotion, massage cream, lotion, face lotion, body lotion, skin nourishing lotion, cold cream, moisturizing cream, emulsion, lotion, pack, after-shaving cream, sun-screening cream, sunian oil, night cream, night lotion, morning lotion, eye cream, eye essence, cleaning cream, makeup, makeup base, foundation, body shampoo, hair shampoo, hair rinse, hair conditioner, hair-nourishing agent, hair-growing agent, stick pomade, hair cream, hair liquid, hair-setting lotion, hair spray, hair dye, hair bleach, coloring rinse, coloring spray, permanent wave liquid, pressed powder, loose powder, eye shadow, hand cream, lipstick, or any combination thereof.

[0084] In some embodiments, a composition of the current disclosure may be used to promote lipolysis, reduce fat, reduce the appearance of fat, reduce celMite, or reduce the appearance of cellulite.

[0085] In some embodiments, the skin infection is benign or non-cancerous. Skin infections of the current disclosure may be contagious. In some embodiments, the skin infection is cancerous. Skin infections of the current disclosure may be noncontagious. In some embodiments, the skin infection is cancer.

[0086] In some embodiments, the composition of the current disclosure retains greater than 50% of the main ingredients after placement in a sealed container for 6 months at a temperature of about 25 °C and a relative humidity level of about 50%. In some embodiments, the

composition of the current disclosure retains at least 80% of the main ingredients after placement in a sealed container for 6 months at a temperature of about 25 °C and a relative humidity level of about 50%.

[0087] A composition of the current disclosure may be packaged into a container selected from the group consisting of a tube, ajar, a vial, a bag, a tray, a drum, a bottle, a syringe, and a can. In some embodiments, a composition of the current disclosure may be packaged into a tube. In some embodiments, a composition of the current disclosure may be packaged into a tube, wherein the tube contains information describing directions for use. In some embodiments, a composition of the current disclosure may be packaged into a tube, wherein the tube contains information describing directions for use.

[0088] Formulations/Administration

[0089] The compositions described herein may contain one or more compounds as active ingredients, and include additives such as excipients, carriers, diluents, permeation enhancers, solubilizers and adjuvants. Excipients include lactose, dextrose, sucrose, sorbitol, mannitol, starches, gum acacia, calcium phosphate, alginates, tragacanth, gelatin, calcium silicate, microcrystalline cellulose, polyvinylpyrrolidone, cellulose, water, sterile saline, syrup, and methyl cellulose. The compositions can additionally include: lubricating agents such as talc, magnesium stearate, mineral oil; wetting agents; emulsifying and suspending agents; preserving agents such as methyl- and propylhydroxy-benzoates; sweetening agents; fragrances; and flavoring agents. The compositions of the disclosure can be formulated so as to provide quick, sustained or delayed release of ingredients after administration to the patient.

[0090] A composition of the current disclosure may optionally comprise other ingredients, including, but not limited to, excipients, fillers, emulsifying agents, antioxidants, surfactants, film formers, chelating agents, gelling agents, thickeners, emollients, humectants, moisturizers, vitamins, minerals, viscosity and/or rheology modifiers, sunscreens, keratolytics, depigmenting agents, retinoids, hormonal compounds, alpha-hydroxy acids, alpha-keto acids, anti- mycobacterial agents, antifungal agents, antimicrobials, antivirals, analgesics, peptides, high molecular peptides, moisturizers, emollients, surfactants, ultraviolet absorbents, pH regulators, lipidic compounds, anti-allergenic agents, anti-inflammatory agents, anti-irritants, antineoplastics, immune system boosting agents, immune system suppressing agents, anti-acne agents, anesthetics, antiseptics, insect repellents, skin cooling compounds, skin protectants, skin penetration enhancers, exfoliants, lubricants, fragrances, colorants, staining agents, depigmenting agents, hypopigmenting agents, preservatives, stabilizers, pharmaceutical agents, photostabilizing agents, spherical powders, and any combination thereof.

[0091] Compositions of the current disclosure may be administered by topical, intradermal, oral, transdermal/transmucosal routes, or any combination thereof.

[0092] A composition may include, for example, one or more of the following: a sterile diluent such as water, saline solution, preferably physiological saline, Ringer's solution, isotonic sodium chloride, fixed oils that may serve as the solvent or suspending medium, polyethylene glycols, glycerin, propylene glycol or other solvents; antibacterial agents; antioxidants; chelating agents; buffers and agents for the adjustment of tonicity such as sodium chloride or dextrose.

[0093] A composition may comprise an oil that has been isolated and purified. The oil can be purified by distillation, by silica gel chromatography, by fluorination, by carbon filtration, by ultrafiltration, by electrodeionization, by mechanical filtration, or any combination thereof.

[0094] A composition may comprise water that has been isolated and purified. The water can be purified by distillation, by fluorination, by deionization, by carbon filtration, by ultrafiltration, by electrodeionization, by mechanical filtration, by reserve osmosis, or any combination thereof.

[0095] Combinations

[0096] For oral formulations, at least one of the compounds described herein can be used alone or in combination with appropriate additives to make tablets, powders, granules or capsules, and if desired, with diluents, buffering agents, moistening agents, preservatives, coloring agents, and flavoring agents. The compounds may be formulated with a buffering agent to provide for protection of the compound from low pH of the gastric environment and/or an enteric coating. A compound included in a pharmaceutical composition may be formulated for oral delivery with a flavoring agent, e.g., in a liquid, solid or semi-solid formulation and/or with an enteric coating

[0097] A composition comprising any one of the compounds described herein may be formulated for sustained or slow release (also called timed release or controlled release). Such compositions be prepared and administered by, for example, oral, intradermal, or topical routes. Sustained-release formulations may contain the compound dispersed in a carrier matrix and/or contained within a reservoir surrounded by a rate controlling membrane. Excipients for use within such formulations are biocompatible, and may also be biodegradable; preferably the formulation provides a relatively constant level of active component release. Non-limiting examples of excipients include water, alcohol, glycerol, chitosan, alginate, chondroitin, Vitamin E, mineral oil, and dimethyl sulfoxide (DMSO). These compositions may be formulated as oral sprays. Compositions for inhalation or insufflation include solutions and suspensions in pharmaceutically acceptable, aqueous or organic solvents, or mixtures thereof, and powders. The liquid or solid compositions may contain suitable pharmaceutically acceptable excipients as described supra. Compositions in preferably pharmaceutically acceptable solvents may be nebulized by use of inert gases. Nebulized solutions may be inhaled directly from the nebulizing device or the nebulizing device may be attached to a face mask tent, or intermittent positive pressure breathing machine. Solution, suspension, or powder compositions may be administered, preferably orally or nasally, from devices which deliver the formulation in an appropriate manner. [0098] For topical use, the compositions can be in the form of emulsions, creams, jelly, solutions, gels, or ointments. Compatible carriers, which may be used in this disclosure, comprise e.g. an aqueous solution, such as saline solutions, oil solutions or ointments.

[0099] A pharmaceutical composition of the disclosure can be made isotonic with blood by the incorporation of a suitable tonicity modifier. A pharmaceutical composition of the disclosure may have a pH of about 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, or 14, as measured by, for example, a pH probe or pH paper. A composition may have a pH from about 4 to about 10. A

pharmaceutical composition may be formulated to be at physiologically neutral pH.

[0100] Kits

[0101] A kit may be made available to the end user. The kit can comprise the composition. The kit can comprise the composition and an application tool. A kit can come in a box. A kit can be any shape. The contents of the kit can be individually packaged. The contents of the kit can be individually wrapped. Such kits may include a container containing a unit dose, an

informational package insert describing the use and attendant benefits of the drugs in treating the disease, and optionally an appliance or device for delivery of the composition.

[0102] The kit may further comprise any device suitable for administration of the

composition. For example, a kit comprising a topical formulation of pharmaceutical

compositions may comprise gel suitable for topical administration and an alcohol wipe for sterilization of the application site.

[0103] In some cases, kits may be provided with instructions. The instructions may be provided in the kit or they may be accessed electronically (e.g., on the World Wide Web). The instructions may provide information on how to use the compositions of the present disclosure. In some embodiments, the kit comprises instructions for use in treating a wart. The instructions may provide information on how to perform the methods of the disclosure. In some embodiments, the kit comprises instructions for methods of treating a wart. In some cases, the instructions may provide dosing information. The instructions may provide drug information such as the mechanism of action, the formulation of the drug, adverse risks, contraindications, and the like. In some cases, the kit may be purchased by a physician or health care provider for administration at a clinic or hospital.

[0104] A user can pay for the kit. The kit can be paid for by cash, credit card, debit card or promotional code. The kit may be available for purchase from a variety of sources. Some non- limiting examples of sources for purchasing the kit are over-the-counter, online, and in specially stores. The kit may be made available by a professional. The kit may be prescribed by a professional.

[0105] In some examples, a method of use can be application of the composition to at least one tooth in a layer. The method of use can be application of the composition to at least a row of teeth. The method of use can be application of the composition to all the teeth of a subject.

[0106] The compositions can be formulated in any suitable application form, such as gels, mouthwashes, toothpowders, toothpastes, dental trays, and disposable plastic strips. They may be formulated into a single formulation or they may be formulated for multi-compartment containers into different formulations.

[0107] The composition may be applied using a brush, a sponge, a bare finger, a roller, an applicator, a cloth, gauze, cotton wool, via a spray bottle, or any combination thereof. An application tool may be used to apply the composition onto a tooth surface. Non-limiting examples of an application tool include a mouthwash, toothpowder, toothpaste, dental tray, disposable plastic strip, spatula, brush, cotton ball, and cotton swab.

[0108] In one example, the method comprises application of the composition onto a toothbrush and brushing a tooth surface with the toothbrush. In another example, the method comprises application of the composition and toothpaste onto a toothbrush and brushing a tooth surface with the toothbrush. In yet another example, the method comprises application of the composition onto a toothbrush and brushing a denture tooth surface with the toothbrush. In another example, the method comprises application of the composition and toothpaste onto a toothbrush and brushing a denture tooth surface with the toothbrush. In one example, the method comprises application of the composition onto a toothbrush and brushing a pet tooth surface with the toothbrush.

[0109] The method of use may include application of the composition onto dental floss. The method of use may include application of the composition onto a dental tray that may be held in contact with a tooth surface. The method of use may include application of the composition onto a disposable plastic strip that may be placed directly on a tooth surface.

[0110] The period of application of the method can be at least 5, 10, 25, 30, 35, 40, 45, 50, 55, 60, 65, 70, 75, 80, 85, 90, 95, 100, 150, 200, 250, 300, 400, or 500 seconds.

[0111] A unit dose can be administered simultaneously or sequentially. The composition can be administered for an extended period of time. The period of time of administration can be about 1 minute, 1 hour, 12 hours, 1 day, 2 days, 3 days, 7 days, 14 days, 28 days, 1 month, 2 months, 3 months, 6 months, 1 year, or more. In some embodiments, the administration period may be until symptoms recede. In some embodiments, the composition is applied for at least 10 seconds, 30 seconds, 1 minute, 2 minutes, 5 minutes, 10 minutes, 1 hour, 2 hours, or more. In some embodiments, the composition is applied for at least 1 hour.

[0112] In some embodiments, a composition of the current disclosure is administered at least once a day, twice a day, three times a day, once a week, twice a week, three times a week, or more.

[0113] In some embodiments, a composition of the current disclosure is administered at least once a day for a period of at least one week. In some embodiments, a composition of the current disclosure is administered at least twice a day for a period of at least one week. In some embodiments, a composition of the current disclosure is administered at least once a day for a period of at least one month.

[0114] In some embodiments, a composition of the current disclosure can be contacted with a skin cell at least once a day for a period of at least one week. In some embodiments, a composition of the current disclosure can be contacted with a skin cell at least twice a day for a period of at least one week. In some embodiments, a composition of the current disclosure can be contacted with a skin cell at least once a day for a period of at least one month.

[0115] In some embodiments, the composition is applied and left on the skin cell. In some embodiments, the composition is applied onto the skin cell, and washed off after a contact period of 10 seconds, 30 seconds, 1 minute, 2 minutes, 5 minutes, 10 minutes, 1 hour, 2 hours, or more.

[0116] In some embodiments, the ingredients of a composition are combined via mixing, blending, adding, stirring, or any combination thereof. The period of time of combining may be at least 1 minute, 5 minutes, 10 minutes, 30 minutes, 1 hour, 2 hours, 5 hours, or more.

[0117] The composition can be applied on a human subject.

[0118] In some aspects, the composition can be applied on a denture.

[0119] In some aspects, the composition can be used on a pet. Some non-limiting examples of a pet include alpaca, cat, cattle, chicken, dog, domestic camel, canary, camel, duck, goose, guinea pig, guineafowl, hedgehog, horse, llama, pigeon, mouse, rabbit, rat, sheep, silver fox, water buffalo, yak and zebu.

[0120] The composition may be applied by a professional. The composition may be applied by the end-user. The composition may be applied at a dental office. The composition may be applied at a home. The composition may be applied at non-dental options. Non-limiting examples of non-dental options include a mall kiosk, a salon, and a spa. EXAMPLES

[0121] The following examples are given for the purpose of illustrating various embodiments of the disclosure and are not meant to limit the present disclosure in any fashion. The present examples; along with the methods described herein are presently representative of preferred embodiments; are exemplary; and are not intended as limitations on the scope of the disclosure. Changes therein and other uses which are encompassed within the spirit of the disclosure as defined by the scope of the claims will occur to those skilled in the art.

A composition was prepared by combining the ingredients listed in Table 1.

TABLE 1.

EXA3MPLE 2;

A composition was prepared by combining the ingredients listed in Table 2. TABLE 2.

A composition was prepared by combining the ingredients listed in Table 3.

TABLE 3.

A composition was prepared by combining the ingredients listed in Table 4. TABLE 4

A composition was prepared by combining the ingredients listed in Table 5.

TABLE 5

A composition was prepared by combining the ingredients listed in Table 6.

TABLE 6

A composition was prepared by combining the ingredients listed in Table 7.

TABLE 7

A composition was prepared by combining the ingredients listed in Table 8.

TABLE 8

A composition was prepared by combining the ingredients listed in Table 10.

TABLE 10

A composition was prepared by combining the ingredients listed in Table 11.

TABLE 11

A composition was prepared by combining the ingredients listed in Table 12.

TABLE 12

EXAMPLE 14: Tooth whitening paste formulation

An oral care composition of the present disclosure in the form of a paste was prepared. The composition of this oral care composition is listed in Table 14 below.

TABLE 14

EXAMPLE 15:

A composition of any of examples 1-13 may be applied to a skin cell. The skin cell may be a human skin cell. A skin cell may be a skin cell of the face, neck, hands, abdomen, thighs, buttocks, toes, feet, scalp, knees, or arms. Appearance of undesired symptoms may decrease, such as appearance of lines or wrinkles is decreased, skin cell looks more radiant, makeup and impurities are removed, or combinations thereof. The composition may be applied using a brush, a sponge, a bare finger, a roller, an applicator, a cloth, gauze, cotton wool, or via a spray bottle. The composition may be applied at least once a day for a period of at least one week.

EXAMPLE 16:

The composition of example 14 may be applied to a tooth surface. The composition may decrease the appearance of wine stains, tobacco stains, coffee stains, or tea stains on the surface of the tooth. The composition may be applied using a brush or a toothbrush. The composition may be applied at least twice a day for a period of at least one week.

Claims

CLAIMS WHAT IS CLAIMED IS:

1. A composition for whitening a tooth surface comprising: a whitening agent, a sugar, a salt, coconut oil, cinnamon oil, clove oil and peppermint oil.

2. The composition of claim 1, wherein said composition further comprises castor oil.

3. The composition of claim 1, wherein said composition further comprises squalane oil.

4. The composition of claim 1, wherein said composition further comprises hemp oil.

5. The composition of claim 1, wherein said composition further comprises black seed oil.

6. The composition of claim 1, wherein said composition further comprises black currant oil.

7. The composition of claim 1, wherein said composition further comprises rose hip oil.

8. The composition of claim 1 , wherein said composition further comprises jojoba oil.

9. The composition of claim 1, wherein said composition further comprises sesame oil.

10. The composition of claim 1, wherein said composition further comprises apricot oil.

11. The composition of claim 1 , wherein said composition further comprises avocado oil.

12. The composition of claim 1, wherein said composition further comprises argan oil.

13. The composition of claim 1, wherein said composition further comprises almond oil.

14. The composition of claim 1, wherein said composition further comprises grape seed oil.

15. The composition of claim 1, wherein said composition further comprises castor oil, squalane oil, hemp oil, black seed oil, black currant oil, rose hip oil, jojoba oil, sesame oil, apricot oil, avocado oil, argan oil, almond oil and grape seed oil.

16. The composition of claim 1, wherein said whitening agent is selected from the group consisting of peroxides, carbonates, bicarbonates, percarbonates, perborates, peroxyacids, and any combination thereof.

17. The composition of claim 1, wherein said whitening agent is a carbonate.

18. The composition of claim 1 , wherein said whitening agent is sodium bicarbonate.

19. The composition of claim 1, wherein said sugar is selected from the group consisting of glucose, fructose, sucrose, erythritol, maltitol, xylitol and any combination thereof.

20. The composition of claim 1, wherein said sugar is xylitol.

21. The composition of claim 1 , wherein said salt is a sea salt.

22. The composition of claim 1, wherein said cinnamon oil, said clove oil, and said

peppermint oil are in a ratio of about 1:1:1.

23. The composition of claim 1, wherein said cinnamon oil, said clove oil, and said

peppermint oil are in a ratio of about 1 :2:3.

24. The composition of claim 1, wherein said cinnamon oil, said clove oil, and said

peppermint oil are in a ratio of about 2:1 :3.

25. The composition of claim 1, wherein said cinnamon oil, said clove oil, and said

peppermint oil are in a ratio of about 3:1 :2.

26. The composition of claim 1, wherein said composition further comprises: castor oil, squalane oil, hemp oil, black seed oil, black currant oil, rose hip oil, jojoba oil, sesame oil, apricot oil, avocado oil, argan oil, almond oil and grape seed oil, and wherein said cinnamon oil, said clove oil, and said peppermint oil are in a ratio of about 2:1 :3.

27. The composition of claim 1, wherein said tooth surface is the tooth surface of a human subject.

28. The composition of claim 1, wherein said tooth surface is the tooth surface of a denture.

29. The composition of claim 1, wherein said tooth surface is the tooth surface of a pet.

30. The composition of claim 1, wherein said composition is suitable for application by a professional dentist.

31. The composition of claim 1 , wherein said composition is suitable for application by a user.

32. The composition of claim 1, wherein said composition is applied to at least one tooth in a layer.

33. The composition of claim 1, wherein the composition is combined with a toothpaste.

34. The composition of claim 1, wherein the composition is suitable for application on a dental floss.

35. The composition of claim 1, wherein the composition is suitable for application on a dental tray

36. The composition of claim 1, wherein the composition is suitable for application on a disposable plastic strip.

37. A tooth whitening kit comprising the composition of claim 1.

38. A tooth whitening kit comprising the composition of claim 1 and an application tool.

39. A tooth whitening kit comprising the composition of claim 26.

40. A tooth whitening kit comprising the composition of claim 26 and an application tool.

41. A method for whitening a tooth surface comprising:

contacting a tooth surface with a composition, wherein said composition comprises: a whitening agent, a sugar, a salt, coconut oil, cinnamon oil, clove oil and peppermint oil.

42. The method of claim 41 , wherein said composition further comprises castor oil.

43. The method of claim 41, wherein said composition further comprises squalane oil.

44. The method of claim 41 , wherein said composition further comprises hemp oil.

45. The method of claim 41 , wherein said composition further comprises black seed oil.

46. The method of claim 41 , wherein said composition further comprises black currant oil.

47. The method of claim 41, wherein said composition further comprises rose hip oil.

48. The method of claim 41 , wherein said composition further comprises jojoba oil.

49. The method of claim 41, wherein said composition further comprises sesame oil.

50. The method of claim 41, wherein said composition further comprises apricot oil.

51. The method of claim 41 , wherein said composition further comprises avocado oil.

52. The method of claim 41 , wherein said composition further comprises argan oil.

53. The method of claim 41, wherein said composition further comprises almond oil.

54. The method of claim 41, wherein said composition further comprises grape seed oil.

55. The method of claim 41, wherein said composition further comprises castor oil, squalane oil, hemp oil, black seed oil, black currant oil, rose hip oil, jojoba oil, sesame oil, apricot oil, avocado oil, argan oil, almond oil and grape seed oil.

56. The method of claim 41 , wherein said whitening agent is selected from the group consisting of peroxides, carbonates, bicarbonates, percarbonates, perborates, peroxyacids, and any combination thereof.

57. The method of claim 41 , wherein said whitening agent is a carbonate.

58. The method of claim 41 , wherein said whitening agent is sodium bicarbonate.

59. The method of claim 41, wherein said sugar is selected from the group consisting of glucose, fructose, sucrose, erythritol, maltitol, xylitol and any combination thereof.

60. The method of claim 41 , wherein said sugar is xylitol.

61. The method of claim 41 , wherein said salt is a sea salt.

62. The method of claim 41, wherein said cinnamon oil, said clove oil, and said peppermint oil are in a ratio of about 1:1:1.

63. The method of claim 41, wherein said cinnamon oil, said clove oil, and said peppermint oil are in a ratio of about 1 :2:3.

64. The method of claim 41 , wherein said cinnamon oil, said clove oil, and said peppermint oil are in a ratio of about 2:1:3.

65. The method of claim 41, wherein said cinnamon oil, said clove oil, and said peppermint oil are in a ratio of about 3:1:2.

66. The method of claim 41, wherein said composition further comprises: castor oil, squalane oil, hemp oil, black seed oil, black currant oil, rose hip oil, jojoba oil, sesame oil, apricot oil, avocado oil, argan oil, almond oil and grape seed oil, and wherein said cinnamon oil, said clove oil, and said peppermint oil are in a ratio of about 2:1:3.

67. The method of claim 41 , wherein said tooth surface is the tooth surface of a human subject.

68. The method of claim 41, wherein said tooth surface is the tooth surface of a denture.

69. The method of claim 41 , wherein said tooth surface is the tooth surface of a pet.

70. The method of claim 41 , comprising application of said composition by a professional dentist.

71. The method of claim 41 , comprising application of said composition by a user .

72. The method of claim 41 , further comprising purchasing from a professional dentist.

73. The method of claim 41 , further comprising purchasing over the counter.

74. The method of claim 41 , comprising application of said composition to at least one tooth in a layer.

75. The method of claim 41 , comprising applying said composition to a tooth surface with a toothbrush.

76. A composition comprising:

a) at least one plant, extract thereof, oil thereof, or a part thereof;

b) i) at least one molecule comprising one alcohol functional group and at least 8 carbon atoms, or a salt thereof; ii) or at least one molecule comprising at least two alcohol functional groups and 2 to 8 carbons, or a salt thereof; or any combination thereof;

c) at least one vitamin, or a salt thereof; and

d) at least one molecule comprising an oxo group, an acidic group, and at least 4 carbons, ester thereof, salt thereof, or any combination thereof;

wherein the composition is topical composition.

77. The composition of claim 76, comprising at least 0.5 volume % of said at least one plant, extract thereof, oil thereof, or a part thereof, wherein said volume % is based on a total volume % of the composition.

78. The composition of claim 76, comprising at least 1 volume % of said at least one plant, extract thereof, oil thereof, or a part thereof, wherein said volume % is based on a total volume % of the composition.

79. The composition of claim 76, comprising at least 2 volume % of said at least one plant, extract thereof, oil thereof, or a part thereof, wherein said volume % is based on a total volume % of the composition.

80. The composition of claim 76, comprising at least 5 volume % of said at least one plant, extract thereof, oil thereof, or a part thereof, wherein said volume % is based on a total volume % of the composition.

81. The composition of claim 76, comprising at least 10 volume % of said at least one plant, extract thereof, oil thereof, or a part thereof, wherein said volume % is based on a total volume % of the composition.

82. The composition of claim 76, wherein said at least one plant, extract thereof, oil thereof, is a plant.

83. The composition of claim 76, wherein said plant is selected from the group consisting of aloe vera, green tea, green tea extract, flaxseed, chamomile, lavender, white tea, and saberry.

84. The composition of claim 76, wherein said at least one plant, extract thereof, oil thereof, is a plant oil.

85. The composition of claim 76, wherein said plant oil has been previously isolated and purified.

86. The composition of claim 76, wherein said plant oil is selected from the group consisting of sunflower oil, evening primrose oil, coconut oil, safflower oil, rosehip oil, olive oil, and borage oil.

87. The composition of claim 76, wherein said at least one plant, extract thereof, oil thereof, is a part of said at least one plant.

88. The composition of claim 76, wherein said part of said at least one plant is selected from the group consisting of aloe vera, green tea, green tea extract, flaxseed, chamomile, lavender, white tea, and saberry.

89. The composition of claim 76, comprising about 1 volume % of sunflower oil, wherein said volume % is based on a total volume % of the composition.

90. The composition of claim 76, comprising about 20 volume % of sunflower oil, wherein said volume % is based on a total volume % of the composition.

91. The composition of claim 76, comprising about 0.5 volume % olive oil, wherein said volume % is based on a total volume % of the composition.

92. The composition of claim 76, comprising about 0.1 volume % evening primrose oil, wherein said volume % is based on a total volume % of the composition.

93. The composition of claim 76, comprising about 0.1 volume % coconut oil, wherein said volume % is based on a total volume % of the composition.

94. The composition of claim 76, comprising about 0.001 volume % cocoa seed butter, wherein said volume % is based on a total volume % of the composition.

95. The composition of claim 76, comprising about 4 volume % safflower oil, wherein said volume % is based on a total volume % of the composition.

96. The composition of claim 76, comprising about 10 volume % safflower oil, wherein said volume % is based on a total volume % of the composition.

97. The composition of claim 76, comprising about 10 volume % aloe vera gel, wherein said volume % is based on a total volume % of the composition.

98. The composition of claim 76, comprising about 50 volume % aloe vera gel, wherein said volume % is based on a total volume % of the composition.

99. The composition of claim 76, comprising about 40 volume % aloe vera extract, wherein said volume % is based on a total volume % of the composition.

100. The composition of claim 76, comprising about 0.001 volume % saffron extract, wherein said volume % is based on a total volume % of the composition.

101. The composition of claim 76, comprising about 0.1 volume % green tea extract, wherein said volume % is based on a total volume % of the composition.

102. The composition of claim 76, comprising about 0.05 volume % flaxseed oil, wherein said volume % is based on a total volume % of the composition.

103. The composition of claim 76, comprising about 0.1 volume % flaxseed oil, wherein said volume % is based on a total volume % of the composition.

104. The composition of claim 76, comprising about 2 volume % hydrogenated castor oil, wherein said volume % is based on a total volume % of the composition.

105. The composition of claim 76, comprising about 0.01 volume % chamomile extract, wherein said volume % is based on a total volume % of the composition.

106. The composition of claim 76, comprising about 0.01 volume % calendula officinalis flower extract, wherein said volume % is based on a total volume % of the composition.

107. The composition of claim 76, comprising about 0.01 volume % rosehip fruit oil, wherein said volume % is based on a total volume % of the composition.

108. The composition of claim 76, comprising about 0.01 volume % tamanu oil, wherein said volume % is based on a total volume % of the composition.

109. The composition of claim 76, comprising about 0.1 volume % hydrolyzed soy protein, wherein said volume % is based on a total volume % of the composition.

110. The composition of claim 76, comprising about 0.01 volume % of saberry extract, wherein said volume % is based on a total volume % of the composition.

111. The composition of claim 76, comprising at least two of said at least one plant, extract thereof, oil thereof, or part thereof.

112. The composition of claim 76, comprising at least three of said at least one plant, extract thereof, oil thereof, or part thereof.

113. The composition of claim 76, comprising at least four of said at least one plant, extract thereof, oil thereof, or part thereof.

114. The composition of claim 76, comprising at least 0.5 volume % of said at least one molecule comprising one alcohol functional group and at least 8 carbons, or a salt thereof; or at least one molecule comprising at least two alcohol functional groups and 2 to 8 carbons, or a salt thereof, wherein said volume % is based on a total volume % of the composition.

115. The composition of claim 76, comprising at least 1 volume % of said at least one molecule comprising one alcohol functional group and at least 8 carbons, or a salt thereof; or at least one molecule comprising at least two alcohol functional groups and 2 to 8 carbons, or a salt thereof, wherein said volume % is based on a total volume % of the composition.

116. The composition of claim 76, comprising at least 2 volume % of said at least one molecule comprising one alcohol functional group and at least 8 carbons, or a salt thereof; or at least one molecule comprising at least two alcohol functional groups and 2 to 8 carbons, or a salt thereof, wherein said volume % is based on a total volume % of the composition.

117. The composition of claim 76, comprising at least 5 volume % of said at least one molecule comprising one alcohol functional group and at least 8 carbons, or a salt thereof; or at least one molecule comprising at least two alcohol functional groups and 2 to 8 carbons, or a salt thereof, wherein said volume % is based on a total volume % of the composition.

118. The composition of claim 76, comprising at least 10 volume % of said at least one molecule comprising one alcohol functional group and at least 8 carbons, or a salt thereof; or at least one molecule comprising at least two alcohol functional groups and 2 to 8 carbons, or a salt thereof, wherein said volume % is based on a total volume % of the composition.

119. The composition of claim 76, wherein said at least one molecule comprising one alcohol functional group comprises an aromatic ring, which can be substituted or unsubstituted.

120. The composition of claim 76, wherein said at least one molecule comprising one alcohol functional group and at least 8 carbons, or a salt thereof; or at least one molecule comprising at least two alcohol functional groups and 2 to 8 carbons, or a salt thereof, is selected from the group consisting of wax, glycerin, glyceryl stearate, stearyl alcohol, phenoxyethanol, glyceryl monolaurate, resveratrol, benzyl alcohol, ethylhexylglyercin, panthenol, cetyl alcohol, soy lecithin, haloxyl, and panthenol.

121. The composition of claim 76, comprising about 1 volume % cetearyl alcohol, wherein said volume % is based on a total volume % of the composition.

122. The composition of claim 76, comprising about 5 volume % cetearyl alcohol, wherein said volume % is based on a total volume % of the composition.

123. The composition of claim 76, comprising about 0.5 volume % glycerin, wherein said volume % is based on a total volume % of the composition.

124. The composition of claim 76, comprising about 1 volume % glycerin, wherein said volume % is based on a total volume % of the composition.

125. The composition of claim 76, comprising about 3 volume % glycerin, wherein said volume % is based on a total volume % of the composition.

126. The composition of claim 76, comprising about 5 volume % glycerin, wherein said volume % is based on a total volume % of the composition.

127. The composition of claim 76, comprising about 3 volume % glyceryl stearate, wherein said volume % is based on a total volume % of the composition.

128. The composition of claim 76, comprising about 5 volume % glyceryl stearate, wherein said volume % is based on a total volume % of the composition.

129. The composition of claim 76, comprising about 2 volume % stearyl alcohol, wherein said volume % is based on a total volume % of the composition.

130. The composition of claim 76, comprising about 1 volume % phenoxyethanol, wherein said volume % is based on a total volume % of the composition.

131. The composition of claim 76, comprising about 1 volume % glyceryl monolaurate, wherein said volume % is based on a total volume % of the composition.

132. The composition of claim 76, comprising about 0.001 volume % resveratrol, wherein said volume % is based on a total volume % of the composition.

133. The composition of claim 76, comprising about 0.5 volume % benzyl alcohol, wherein said volume % is based on a total volume % of the composition.

134. The composition of claim 76, comprising about 0.2 volume % ethylhexylglycerin, wherein said volume % is based on a total volume % of the composition.

135. The composition of claim 76, comprising about 1 volume % emulsifying wax, wherein said volume % is based on a total volume % of the composition.

136. The composition of claim 76, comprising about 0.1 volume % panthenol, wherein said volume % is based on a total volume % of the composition.

137. The composition of claim 76, comprising about 0.3 volume % panthenol, wherein said volume % is based on a total volume % of the composition.

138. The composition of claim 76, wherein said at least one alcohol functional group and at least 8 carbons, or a salt thereof; or at least one molecule comprising at least two alcohol functional groups and 2 to 8 carbons, or a salt thereof

139. The composition of claim 76, comprising at least two of said at least one alcohol functional group and at least 8 carbons, or a salt thereof; or at least one molecule comprising at least two alcohol functional groups and 2 to 8 carbons, or a salt thereof.

140. The composition of claim 76, comprising at least three of said at least one alcohol functional group and at least 8 carbons, or a salt thereof; or at least one molecule comprising at least two alcohol functional groups and 2 to 8 carbons, or a salt thereof.

141. The composition of claim 76, comprising at least four of said at least one alcohol functional group and at least 8 carbons, or a salt thereof; or at least one molecule comprising at least two alcohol functional groups and 2 to 8 carbons, or a salt thereof.

142. The composition of claim 76, comprising at least 0.5 volume % of said at least one vitamin, or a salt thereof.

143. The composition of claim 76, comprising at least 1 volume % of said at least one vitamin, or a salt thereof.

144. The composition of claim 76, comprising at least 2 volume % of said at least one vitamin, or a salt thereof.

145. The composition of claim 76, comprising at least 5 volume % of said at least one vitamin, or a salt thereof, wherein said volume % is based on a total volume % of the composition.

146. The composition of claim 76, comprising at least 10 volume % of said at least one vitamin, or a salt thereof, wherein said volume % is based on a total volume % of the

composition.

147. The composition of claim 76, wherein said at least one vitamin, or a salt thereof, is a water-soluble vitamin.

148. The composition of claim 76, wherein said water-soluble vitamin is selected from vitamin B₁, vitamm B₂ vitamm B₆, pyridoxine, pyridoxine hydrochloride, vitamin Bj₂, pantothenic acid, nicotinic acid, nicotinamide, folic acid, vitamin C and vitamin H.

149. The composition of claim 76, wherein said at least one vitamin is an oil-soluble vitamin selected from the group consisting of vitamin A, carotene, vitamin D₂, vitamin D₃ and vitamin E.

150. The composition of claim 76, comprising about 0.1 volume % of vitamin E, wherein said volume % is based on a total volume % of the composition.

151. The composition of claim 76, comprising about 1 volume % of vitamin E, wherein said volume % is based on a total volume % of the composition.

152. The composition of claim 76, comprising about 1 volume % of vitamin C, wherein said volume % is based on a total volume % of the composition.

153. The composition of claim 76, comprising at least two of said at least one vitamin, or a salt thereof.

154. The composition of claim 76, comprising at least three of said at least one vitamin, or a salt thereof.

155. The composition of claim 76, comprising at least four of said at least one vitamin, or a salt thereof.

156. The composition of claim 76, comprising at least 0.5 volume % of said at least one molecule comprising an oxo group, an acidic group, and at least 4 carbons, ester thereof, salt thereof, or any combination thereof, wherein said volume % is based on a total volume % of the composition.

157. The composition of claim 76, comprising at least 1 volume % of said at least one molecule comprising an oxo group, an acidic group, and at least 4 carbons, ester thereof, salt thereof, or any combination thereof, wherein said volume % is based on a total volume % of the composition.

158. The composition of claim 76, comprising at least 2 volume % of said at least one molecule comprising an oxo group, an acidic group, and at least 4 carbons, ester thereof, salt thereof, or any combination thereof, wherein said volume % is based on a total volume % of the composition.

159. The composition of claim 76, comprising at least 5 volume % of said at least one molecule comprising an oxo group, an acidic group, and at least 4 carbons, ester thereof, salt thereof, or any combination thereof, wherein said volume % is based on a total volume % of the composition.

160. The composition of claim 76, comprising at least 10 volume % of said at least one molecule comprising an oxo group, an acidic group, and at least 4 carbons, ester thereof, salt thereof, or any combination thereof, wherein said volume % is based on a total volume % of the composition.

161. The composition of claim 76, wherein said at least one molecule comprising an oxo group, an acidic group, and at least 4 carbons, ester thereof, salt thereof, or any combination thereof, is selected from the group consisting of octyl palmitate, argireline, hyaluronic acid, soy lecithin, carbomer, sodium CI 4- 16 olefin sulfonate, cocamidopropyl betaine, sodium benzoate, potassium sorbate, citric acid, disodium cocyl glutamate, polyglyceryl-4 isostearate, cetyl dimethicone, hexyl laurate, and magnesium ascorbyl phosphate.

162. The composition of claim 76, comprising about 3 volume % of octyl palmitate, wherein said volume % is based on a total volume % of the composition.

163. The composition of claim 76, comprising about 4 volume % of octyl palmitate, wherein said volume % is based on a total volume % of the composition.

164. The composition of claim 76, comprising about 1 volume % of stearic acid, wherein said volume % is based on a total volume % of the composition.

165. The composition of claim 76, comprising about 10 volume % of sodium CI 4- 16 olefin sulfonate, wherein said volume % is based on a total volume % of the composition.

166. The composition of claim 76, comprising about 15 volume % of sodium CI 4- 16 olefin sulfonate, wherein said volume % is based on a total volume % of the composition.

167. The composition of claim 76, comprising about 0.1 volume % of citric acid, wherein said volume % is based on a total volume % of the composition.

168. The composition of claim 76, comprising about 28 volume % of capric triglyceride, wherein said volume % is based on a total volume % of the composition.

169. The composition of claim 76, comprising about 0.1 volume % of sodium benzoate, wherein said volume % is based on a total volume % of the composition.

170. The composition of claim 76, comprising about 0.1 volume % of potassium sorbate, wherein said volume % is based on a total volume % of the composition.

171. The composition of claim 76, comprising about 1 volume % of hyaluronic acid, wherein said volume % is based on a total volume % of the composition.

172. The composition of claim 76, comprising about 0.1 volume % of hyaluronic acid, wherein said volume % is based on a total volume % of the composition.

173. The composition of claim 76, comprising at least two of said at least one molecule comprising an oxo group, an acidic group, and at least 4 carbons, ester thereof, salt thereof, or any combination thereof.

174. The composition of claim 76, comprising at least three of said at least one molecule comprising an oxo group, an acidic group, and at least 4 carbons, ester thereof, salt thereof, or any combination thereof.

175. The composition of claim 76, comprising at least four of said at least one molecule comprising an oxo group, an acidic group, and at least 4 carbons, ester thereof, salt thereof, or any combination thereof.

176. The composition of claim 76, further comprising a compound selected from the group consisting of a fragrance, a dye, a preservative, a protein, and a stabilizing agent.

177. The composition of claim 76, wherein said fragrance is selected from the group consisting of fragrance citrus punch, fragrance clean linen, fragrance coconut, fragrance coconut lime verbena, fragrance coral reef, fragrance lemon verbena, fragrance mandarin-berry, fragrance mangosteen, fragrance neroli, fragrance peppermint oil, fragrance pineapple lily, fragrance sweet orange essential oil, fragrance tea tree essential oil, fragrance vanilla grapefruit, fragrance white peach & ginger, and fragrance white tea.

178. The composition of claim 76, wherein said dye is selected from the group consisting of D&C Red Nos. 2, 5, 6, 7, 10, 11, 12, 13, 30, 34, D&C Yellow No. 5, D&C Blue No. 1, a metal oxide, and a metal hydroxide.

179. The composition of claim 76, wherein said preservative is selected from the group consisting of methylparaben, propylparaben, and butylparaben.

180. The composition of claim 76, further comprising at least one metal cation.

181. The composition of claim 76, wherein said at least one metal cation is selected from sodium, magnesium, calcium, or ammonium.

182. The composition of claim 76, wherein said composition is formulated into a topical solution, a lotion, a liquid, a cream, an ointment, a gel, a foam, a patch, a powder, onto a sponge, a paste, a tincture, an emulsion, or any combination thereof.

183. The composition of claim 76, wherein said composition is formulated into a cream, an ointment, or a gel.

184. The composition of claim 76, wherein said composition is formulated into a cream.

185. The composition of claim 76, wherein said composition is formulated into a gel.

186. The composition of claim 76, wherein said composition is homogeneous.

187. The composition of claim 76, wherein said composition is heterogeneous.

188. The composition of claim 76, wherein said composition retains at least 80%, 85%, or 90% of said ingredients after placement in a sealed container for 6 months at a temperature of about 25 °C and a relative humidity level of about 50%.

189. The composition of claim 76, wherein said composition is contained in a kit.

190. The composition of claim 76, wherein said kit further comprises instructions for use.

191. The composition of claim 76, wherein said composition is packaged into a container selected from the group consisting of a tube, ajar, a vial, a bag, a tray, a drum, a bottle, a syringe, and a can.

192. The composition of claim 76, wherein said composition is packaged into a container selected from the group consisting of a tube, ajar, and a vial.

193. The composition of claim 76, wherein said tube contains information describing directions for use.

194. A method for treatment of a skin condition comprising contacting of a composition of any proceeding claim to a subject in need thereof.

195. The method of claim 194, wherein said composition is contacted with a skin cell.

196. The method of claim 194, wherein said skin cell is a human skin cell.

197. The method of claim 194, wherein said skin cell, an area of skin around said skin cell, or both, is first washed and dried before said contact.

198. The method of claim 194, wherein said skin cell is a skin cell of the face, neck, or hands.

199. The method of claim 194, wherein said skin cell is a skin cell of the face, abdomen, thighs, buttocks, or arms.

200. The method of claim 194, wherein said skin cell is a skin cell of the face.

201. The method of claim 194, wherein elasticity of said skin cell is enhanced, appearance of lines or wrinkles is decreased, said skin cell looks more radiant, makeup and impurities are removed, or combinations thereof, after said application.

202. The method of claim 194, wherein said elasticity or said appearance of lines or wrinkles is evaluated by taking before and after photographs.

203. The method of claim 194, further comprising application of an adhesive bandage to said area of skin after said contact.

204. The method of claim 194, wherein said composition is contacted for a period of time of at least 1 second.

205. The method of claim 194, wherein said composition is contacted for a period of time of at least 1 minute.

206. The method of claim 194, wherein said composition is contacted for a period of time of at least 1 hour.

207. The method of claim 194, wherein said composition is contacted at least once a day for a period of at least one week.

208. The method of claim 194, wherein said composition is contacted twice a day for a period of at least one week.

209. The method of claim 194, wherein said composition is contacted twice a day for a period of at least one month.

210. The method of claim 194, wherein said composition is applied using a brush, a sponge, a bare finger, a roller, an applicator, a cloth, gauze, cotton wool, via a spray bottle, or any combination thereof.

211. The method of claim 194, wherein said composition is applied using a brush, a sponge, or a bare finger.

212. The method of claim 194, wherein said composition is applied with water.

213. The method of claim 194, wherein said composition is washed off after said contact.

214. The method of claim 194, wherein said skin cell exhibits a symptom.

215. The method of claim 194, wherein said symptom is selected from the group consisting of a dry patch of skin, a wart, a bump, a dark spot, a colored speck, coloration of a patch of skin, peeling of skin, soreness of skin, an abnormal skin growth, a rash, an itch, scaly or rough skin, dry, cracked skin, chafing and peeling skin, open sores or lesions, changes in mole color or size, loss of skin pigment, excessive flushing with or without stimulus discolored patches of skin, and any combination thereof.

216. The method of claim 194, wherein said symptom is selected from the group consisting of a dry patch of skin, coloration of a patch of skin, peeling of skin, soreness of skin, a rash, an itch, scaly skin, rough skin,, and any combination thereof.

217. The method of claim 194, wherein said method reduces the appearance of said symptom.

218. The method of claim 194, wherein said method exhibits efficacy greater than about 50% compared to a method employing a composition comprising an ingredient selected from the group consisting of ammonium lactate and lactic acid.

219. The method of claim 194, wherein components in said composition act synergistically to reduce the appearance of said symptom.

220. The method of claim 194, wherein components in said composition act synergistically and have a combination index of less than 1.

221. The method of claim 194, wherein said subject is human.

222. The method of claim 194, wherein said subject has previously been treated for a medical condition via a medical procedure.

223. The method of claim 194, wherein said medical procedure is selected from the group consisting of radiation therapy, burn treatment, or chemotherapy.

224. A method of combining:

a) at least one plant, extract thereof, oil thereof, or a part thereof;

b) at least one molecule comprising one alcohol functional group and at least 8 carbons, or a salt thereof; or at least one molecule comprising at least two alcohol functional groups and 2 to 8 carbons, or a salt thereof;

c) at least one vitamin, or a salt thereof; and

d) at least one molecule comprising an oxo group, an acidic group, and at least 4 carbons, ester thereof, salt thereof, or any combination thereof.

225. The method of claim 194, wherein said method of combining is selected from the group consisting of mixing, blending, adding, stirring, and any combination thereof.

226. The method of claim 194, wherein said method of combining occurs for a period of time of at least 1 minute.

227. The method of claim 194, wherein said method of combining occurs for a period of time of at least 30 minutes.