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WO2014003039A1 - Lentille intraoculaire - Google Patents

Lentille intraoculaire Download PDF

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Publication number
WO2014003039A1
WO2014003039A1 PCT/JP2013/067458 JP2013067458W WO2014003039A1 WO 2014003039 A1 WO2014003039 A1 WO 2014003039A1 JP 2013067458 W JP2013067458 W JP 2013067458W WO 2014003039 A1 WO2014003039 A1 WO 2014003039A1
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WO
WIPO (PCT)
Prior art keywords
intraocular lens
optical
flexible
lens
capsule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2013/067458
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English (en)
Japanese (ja)
Inventor
正信 井上
次郎 日高
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoya Corp
Original Assignee
Hoya Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoya Corp filed Critical Hoya Corp
Publication of WO2014003039A1 publication Critical patent/WO2014003039A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1624—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside
    • A61F2/1635—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside for changing shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2002/1681—Intraocular lenses having supporting structure for lens, e.g. haptics
    • A61F2002/16901—Supporting structure conforms to shape of capsular bag

Definitions

  • the present invention relates to an intraocular lens that is inserted into the eye as an alternative function of the crystalline lens.
  • An intraocular lens used for treatment is composed of an optical part that functions as a lens and a support part that supports the optical part.
  • intraocular lenses that can be inserted through small incisions, specifically intraocular lenses having an optical part made of a soft material, have become mainstream.
  • the optical part is made of a soft material, so that the optical part can be bent and inserted from a small incision.
  • one-piece type intraocular lenses in which the support portion and the optical portion are made of the same material are becoming widespread for the purpose of easy insertion into the eye and strengthening of the connection portion between the support portion and the optical portion.
  • One of the important factors in considering an intraocular lens is to stably hold the intraocular lens in the eye (in the lens capsule).
  • the intraocular lens is deviated or tilted from the center of the crystalline lens capsule during or after the operation, the target visual acuity cannot be obtained.
  • the lens in which the optical unit can be folded, if the lens is held in an unstable state in the lens capsule, the lens itself may be deformed. For this reason, it is important to stably hold the intraocular lens in the lens capsule.
  • techniques described in Patent Documents 1 to 3 are known as techniques aiming to stably hold the intraocular lens in the lens capsule.
  • a technique described in Patent Document 4 is known as a technique relating to the position and displacement of the intraocular lens within the lens capsule.
  • the capsular bag contracts after the operation. At this time, an inward force is applied to the support portion of the intraocular lens. Furthermore, when the capsular bag contracts over time after the operation, the posterior bag of the capsular bag comes into contact with the optical part of the intraocular lens. Conventionally, when an inward force is applied to the support portion due to contraction of the lens capsule after insertion of the intraocular lens, the optical portion may move forward and come into contact with the iris. If the optical part of the intraocular lens comes into contact with the iris, it may cause inflammation.
  • the support part is obliquely bent with respect to the optical part, thereby bringing the optical part closer to the posterior capsule side (the side away from the iris).
  • the structure of a mold used for manufacturing an intraocular lens (such as a cast mold manufacturing method) is compared with a configuration in which the support portion is formed in parallel with the optical portion. Inconveniences such as complicated and (b) the process of cutting out the intraocular lens from the molded lens substrate become troublesome.
  • the cross-sectional shape of the support portion in contact with the equator portion of the crystalline lens capsule is set to a triangle or the like.
  • the inclined part of the support part 53 having a triangular cross-section supporting the optical part 52 of the intraocular lens 51 is a crystalline lens. It follows the shape of the anterior capsule side of the sac 54. For this reason, when the optical part 52 and the support part 53 are formed flat, the optical part 52 is disposed at a position closer to the front side Fs than the equator of the lens capsule 54 (indicated by a dashed line in the figure).
  • Patent Document 4 also describes a configuration in which the support portion of the intraocular lens has a two-layer structure of a hard material and a soft material.
  • the support part is made to conform to the shape of the anterior capsule side, and inward force due to contraction of the lens capsule is received obliquely by the support part.
  • this configuration is adopted, the manufacturing of the intraocular lens is complicated as compared with the above-described one-piece type, which causes a significant cost increase.
  • the main object of the present invention is to provide a technique capable of making it difficult for the intraocular lens to come into contact with the iris and suppressing the tilt of the intraocular lens in the lens capsule.
  • the first aspect of the present invention is: An optical part having two optical surfaces; and a support part formed in a state of extending outward from an outer peripheral part of the optical part to support the optical part, and one optical surface of the optical part is An intraocular lens that is used in the lens capsule of the eyeball so that the front and other optical surfaces face the back,
  • the support portion is disposed along the equatorial portion of the lens capsule when inserted into the lens capsule, and has a flexible portion that elastically deforms by receiving an inward force due to contraction of the lens capsule,
  • the rear side of the outer surface of the flexible part in contact with the equator portion in the lens capsule is formed in an inclined state or a notched state so as to follow the shape of the posterior capsule side of the lens capsule. It is an intraocular lens.
  • the second aspect of the present invention is:
  • the cross-sectional shape of the flexible part in contact with the equator part is such that the optical part moves to the rear side when the flexible part is elastically deformed by receiving the inward force.
  • the third aspect of the present invention is:
  • the cross-sectional shape of the flexible portion in contact with the equator portion has two main shapes in which the central position when the flexible portion receives the inward force in the thickness direction of the support portion defines the thickness of the support portion. It is the shape located in the said front side rather than the center position between surfaces. It is an intraocular lens as described in the said 1st or 2nd aspect characterized by the above-mentioned.
  • the fourth aspect of the present invention is:
  • the cross-sectional shape of the flexible part in contact with the equator part is such that when the inward force is applied to the flexible part, the inward force with respect to the flexible part is more forward than the rear side.
  • the intraocular lens according to any one of the first to third aspects, wherein the intraocular lens has an asymmetric shape so as to act strongly on the eye.
  • the cross-sectional shape of the flexible portion includes an inclined surface formed in a state where a part of the outer surface of the flexible portion is formed and a rear side of the outer surface is obliquely cut out.
  • the intraocular lens according to any one of the first to fourth aspects.
  • the sixth aspect of the present invention is: The intraocular lens according to any one of the first to fifth aspects, wherein the optical part and the support part are made of the same soft material.
  • the seventh aspect of the present invention is The intraocular lens according to any one of the first to sixth aspects, wherein the support portion is formed in an open loop shape.
  • the eighth aspect of the present invention is The intraocular lens according to any one of the first to seventh aspects, wherein a thickness dimension of the support portion is 0.3 mm or more.
  • the intraocular lens can be made difficult to come into contact with the iris, and the inclination of the intraocular lens in the lens capsule can be suppressed.
  • FIG. 1 It is a figure explaining the planar cross-section of an eyeball.
  • the structure of the intraocular lens which concerns on embodiment of this invention is shown, (A) is a top view, (B) is a side view. It is an enlarged view which shows an example of the cross-sectional shape of the flexible part of the intraocular lens which concerns on embodiment of this invention. It is a figure explaining the installation state of an intraocular lens. It is a figure explaining the malfunction which may occur at the time of insertion of an intraocular lens, and the solution reason. It is an enlarged view (the 1) which shows the other example of the cross-sectional shape of a flexible part. It is an enlarged view (the 2) which shows the other example of the cross-sectional shape of a flexible part. It is an enlarged view (the 3) which shows the other example of the cross-sectional shape of a flexible part. It is the figure which compared the support state of the intraocular lens in a lens capsule.
  • FIG. 1 is a diagram illustrating a planar cross-sectional structure of an eyeball.
  • the eyeball 1 has a spherical shape as a whole and is covered and protected by the sclera 3 except for the front cornea 2.
  • the surface of the sclera 3 around the cornea 2 is covered with a conjunctiva 4.
  • the cornea 2 functions not only as an eyeball protection function but also as a lens that refracts incoming light.
  • On the inner side (back side) of the cornea 2 is an anterior chamber 5 filled with aqueous humor, and a pupil 7 is located in the center of the iris 6 facing the anterior chamber 5.
  • the iris 6 functions to adjust the amount of light incident on the inside of the eyeball 1 by adjusting the size of the pupil 7 (the size of the opening).
  • the front surface of the crystalline lens 8 faces the pupil 7.
  • the crystalline lens 8 has a shape like a convex lens and functions to adjust the focal point.
  • the crystalline lens 8 is encased in a crystalline lens capsule made of a transparent thin film.
  • a ciliary body 10 is connected to the crystalline lens 8 via a ciliary band 9.
  • the ciliary body 10 is a tissue that performs focusing by controlling the thickness of the crystalline lens 8.
  • the vitreous body 11 occupies most of the inside of the eyeball 1.
  • the vitreous body 11 is a jelly-like colorless and transparent tissue, and maintains the shape and elasticity of the eyeball 1.
  • the vitreous body 11 transmits the light refracted by the crystalline lens 8 to the retina 13.
  • the retina 13 is a membrane tissue located on the innermost side in the eyeball 1. In the retina 13, there are photoreceptor cells that sense light incident into the eyeball 1 through the pupil 7 and identify its intensity, color, shape, and the like.
  • the choroid 14 is a membrane tissue located inside the sclera 3 (that is, between the sclera 3 and the retina 13).
  • the choroid 14 is rich in blood vessels, and also serves as a blood flow path to each tissue of the eyeball 1 to give nutrition to the eyeball 1.
  • an optic nerve 15 is connected to the back side (back side) of the eyeball 1.
  • the optic nerve 15 is a nerve that transmits light stimulation received by the retina 13 to the brain.
  • a blind spot 16 is present at a portion where the optic nerve 15 is connected.
  • the blind spot 16 is located 4 to 5 mm away from the fovea 17.
  • Configuration of intraocular lens> 2A and 2B show a configuration of an intraocular lens according to an embodiment of the present invention, where FIG. 2A is a plan view and FIG. 2B is a side view.
  • the intraocular lens 21 includes an optical unit 22 that performs an optical lens function and a pair of support units 23 that support the optical unit 22.
  • the optical part 22 and the support part 23 have an integrated structure.
  • the intraocular lens 21 including the optical part 22 and the support part 23 is formed flat as a whole. In other words, the optical unit 22 and the support unit 23 are formed in parallel with each other with respect to a virtual plane orthogonal to the optical axis of the intraocular lens 21.
  • the optical unit 22 is formed in a convex lens shape having a circular shape in plan view.
  • the optical unit 22 has two optical surfaces 22a and 22b.
  • the one optical surface 22a is disposed so as to face the front side Fs, and the other optical surface 22b faces the back side Rs.
  • the “front side Fs” described here corresponds to the outside of the eyeball when the intraocular lens 21 is housed in the crystalline lens capsule of the eyeball, and the “rear side Rs” corresponds to the center side of the eyeball.
  • one optical surface 22a is arranged facing the anterior capsule side
  • the other optical surface 22b is arranged facing the posterior capsule side.
  • the “front side Fs” and “rear side Rs” of the intraocular lens 21 can be identified by the difference in curvature radius between the optical surfaces 22a and 22b.
  • the diameter D of the optical unit 22 may be set to any size as long as it is a size suitable for inserting the intraocular lens 21 into the intraocular lens capsule.
  • the diameter D of the optical unit 22 is preferably set in the range of 5 mm to 7 mm, more preferably 6 mm. What is necessary is just to set the thickness of the optical part 22 according to a desired refractive index.
  • the optical unit 22 is made of a soft material having light transmittance. Specifically, the optical unit 22 is made of a soft material such as a silicone resin, an acrylic resin, a hydrogel, or a urethane resin. Thereby, the optical part 22 can be folded.
  • the term “foldable” described here is used to mean that the intraocular lens 21 including the lens portion 22 can be folded at least in half.
  • the support part 23 is formed in a state extending outward from the outer peripheral part of the optical part 22.
  • the support part 23 is a part that supports the optical part 22 when the intraocular lens 21 is inserted into the eye.
  • Two support portions 23 are formed on one intraocular lens 21.
  • Each support portion 23 draws an arc in a counterclockwise direction in the drawing from a portion where an axis passing through the center C of the optical portion 22 (indicated by a one-dot chain line in the figure) intersects the outer peripheral portion of the optical portion 22. It extends to.
  • the support part 23 has the base part 24 and the flexible part 25 integrally.
  • the base portion 24 is formed in a state adjacent to the outer peripheral portion of the optical unit 22 in the diameter direction of the optical unit 22. Further, the base portion 24 is formed in a mountain-like shape and is joined to the optical unit 22 at the widest portion.
  • the flexible part 25 has moderate flexibility.
  • the flexible portion 25 is curved so as to draw a smooth arc starting from the boundary with the base portion 24.
  • the distal end portion of the support portion 23 serving as the extending end of the flexible portion 25 has a rounded shape (round shape).
  • the flexible portion 25 is configured to be elastically deformable due to the flexibility of the flexible portion 25 itself.
  • the flexible part 25 extends in a slender shape as a whole, and the material itself constituting the flexible part 25 has appropriate flexibility.
  • the flexible portion 25 is integrally formed of the same soft material as that of the optical portion 22 together with the root portion 24 described above.
  • the intraocular lens 21 corresponds to a one-piece type intraocular lens.
  • the support portion 23 (mainly the flexible portion 25) can be elastically deformed by receiving this force. It has a configuration.
  • the “inward force” described here refers to a force toward the center C side of the optical unit 22.
  • FIG. 3 shows a cross-sectional shape when the flexible portion 25 is cross-sectioned at the QQ position in FIG. 2 (A), for example.
  • the width direction of the support portion 23 is denoted as the X direction
  • the length direction of the support portion 23 is denoted as the Y direction
  • the thickness direction of the support portion 23 is denoted as the Z direction.
  • the side surface positioned at the “outer side Os” is positioned at the outer side surface 26 and the “inner side Is”.
  • the side surface to be used is the inner side surface 27.
  • the “inside Is” described here refers to the side facing the optical unit 22, and the opposite side is referred to as “outside Os”.
  • the “front Fs” main surface is the front main surface 28, and the “rear Rs” main surface is the rear main surface 29.
  • the front main surface 28 and the rear main surface 29 are both parallel to a virtual plane orthogonal to the optical axis of the intraocular lens 21 (optical unit 22).
  • the outer surface 26 of the flexible portion 25 is disposed so as to face the equator portion of the lens capsule (hereinafter also simply referred to as “equator portion”) when the intraocular lens 21 is normally housed in the lens capsule. .
  • the flexible portion 25 is a portion that receives an inward force due to contraction of the lens capsule.
  • the equator of the capsular bag is the boundary between the anterior and posterior capsules.
  • the outer surface 26 of the flexible portion 25 is formed by an outer end surface 30 that forms a right angle with the front main surface 28, and an inclined surface 31 that has an angle ⁇ ( ⁇ > 0 degrees) with respect to the outer end surface 30. ing.
  • the outer end surface 30 is formed on the front side Fs of the flexible portion 25, and the inclined surface 31 is the rear side of the flexible portion 25. Rs is formed.
  • the outer end surface 30 is formed in a state parallel to the inner side surface 27, and the inclined surface 31 is a state in which the rear side Rs of the outer surface 26 is obliquely cut out so as to follow the shape of the posterior capsule side of the lens capsule.
  • the inclination angle ⁇ of the inclined surface 31 is preferably set in the range of 30 to 50 degrees, more preferably in the range of 35 to 45 degrees, and still more preferably 40 degrees.
  • the inclined surface 31 is continuously formed over substantially the entire length of the flexible portion 25 in the length direction Y of the support portion 23.
  • the inclined surface 31 is continuously formed from the flexible portion 25 to a part of the root portion 24.
  • the cross-sectional shape of the flexible portion 25 in the direction orthogonal to the length direction Y of the support portion 23 is as follows (1) to ( The shape corresponds to any of 3).
  • the cross-sectional shape of the flexible portion 25 is such that the cross-sectional area S1 of the front side Fs is rearward so that the optical portion 22 moves to the rear side Rs when the flexible portion 25 is elastically deformed by receiving an inward force.
  • the shape is larger than the cross-sectional area S2 of the side Rs.
  • the cross-sectional area S1 of the front side Fs is the center when the cross-sectional shape of the flexible portion 25 is divided into two at the center position P1 between the two main surfaces 28 and 29 defining the thickness of the support portion 23.
  • the area of the cross-sectional part located in front Fs rather than the position P1 is said.
  • the cross-sectional area S2 on the rear side Rs refers to the area of the cross-sectional portion located on the rear side Rs from the center position P1.
  • the boundary between the outer end surface 30 and the inclined surface 31 coincides with the center position P1.
  • the cross-sectional shape of the flexible portion 25 is a shape in which the cross-sectional area S1 of the front side Fs is larger than the cross-sectional area S2 of the rear side Rs due to the presence of the notch portion by the inclined surface 31.
  • the cross-sectional shape of the flexible portion 25 is such that the central position (hereinafter also referred to as “pressure center position”) P2 when the flexible portion 25 receives an inward force in the thickness direction Z of the support portion 23.
  • the shape is located on the front side Fs with respect to the center position P1 between the two main surfaces 28 and 29 defining the thickness of the support portion 23. Further, the pressing center position P2 is shifted to the front side Fs by the ⁇ dimension from the center position P1.
  • the ⁇ dimension is equivalent to 1 ⁇ 4 of the thickness dimension of the support portion 23.
  • the dimensional relation is other than this. May be.
  • the thickness direction Z of the support portion 23 for example, when the center portion of the outer end surface 30 is recessed, inward force is applied to both end portions of the outer end surface 30 across the recessed portion. Therefore, the pressing center position P2 does not change greatly depending on the presence or absence of the recessed portion.
  • the cross-sectional shape of the flexible portion 25 is such that when the inward force described above is applied to the flexible portion 25, the inward force is applied to the flexible portion 25 on the front side Fs rather than the rear side Rs. It has an asymmetric shape to work strongly. More specifically, the cross-sectional shape of the flexible portion 25 is, for example, an asymmetric shape in the front-rear direction (up and down) when viewed with reference to a one-dot chain line indicating the center position P1 in FIG.
  • an intraocular lens insertion device (not shown) with the intraocular lens 21 attached in advance into the eye through the mouth of the eyeball, and pushing the intraocular lens 21 out of the intraocular lens insertion device in that state, The intraocular lens 21 is inserted into the eye (in the lens capsule) through the wound.
  • the intraocular lens 21 is folded into a small shape within the intraocular lens insertion device when the intraocular lens 21 is attached to the intraocular lens insertion device.
  • the intraocular lens 21 inserted into the eye expands (restores) to its original shape as time passes.
  • the position of the intraocular lens 21 accommodated in the lens capsule is inappropriate, the position of the intraocular lens 21 is adjusted using an instrument or the like.
  • the flexible portion 25 of each support portion 23 extending from the optical portion 22 contacts the equator portion of the lens capsule 34 with an appropriate pressure, The optical unit 22 is supported using this contact pressure.
  • the optical surface 22a of the optical unit 22 is disposed on the side facing the anterior capsule 34a, and the optical surface 22b is disposed on the side facing the posterior capsule 34b.
  • the intraocular lens 21 according to the embodiment of the present invention, the following effects are obtained. That is, when the intraocular lens 21 is inserted into the capsular bag 34, since the inclined surface 31 is formed on the outer surface 26 of the flexible portion 25 of the support portion 23, the intraocular lens 21 is inclined or misaligned. It is installed in an appropriate position without having to. The reason is as follows.
  • the inclined surface 31 is formed on the outer surface 26 of the flexible portion 25, the cross-sectional shape of the flexible portion 25 is equator due to the presence of the inclined surface 31, as shown in FIG. Therefore, the edge portion of the outer surface 26 of the flexible portion 25 is not easily caught by the equator portion of the lens capsule 34.
  • the inclined surface 31 of the outer surface 26 of the flexible portion 25 is inclined so as to follow the shape of the capsular bag 34 and the sectional shape of the flexible portion 25 including the inclined surface 31 is The shape follows the shape of the equator. For this reason, the accommodation degree of the flexible part 25 with respect to the equator part of the crystalline lens capsule 34 becomes favorable.
  • the inclination of the intraocular lens 21 can be suppressed and supported in a stable state.
  • the intraocular lens 21 is stably supported, so that an effect of reducing the risk of occurrence of positional deviation or the like can be obtained.
  • the same effect can be obtained by reducing the thickness dimension of the entire support part 23 including the flexible part 25.
  • the thickness dimension of the support part 23 is reduced, the rigidity and strength required for the support part 23 to properly support the optical part 22 may not be ensured.
  • the thickness dimension of the support part 23 two main surfaces
  • the thickness dimension of the support part 23 is 0.3 mm or more, if the inclined surface 31 is formed on the outer surface 26 of the flexible part 25, the fit to the equator part is improved and the intraocular lens 21 is formed. Can be installed stably.
  • the optical unit 52 is arranged at a position closer to the front side Fs than the equator (indicated by a one-dot chain line in the figure).
  • the outer end surface 30 of the outer end surface 30 and the inclined surface 31 constituting the outer surface 26 of the flexible portion 25 is the equator of the lens capsule 34.
  • the inclined surface 31 is arranged along the shape of the posterior capsule side of the crystalline lens capsule 34. For this reason, as shown in FIG.
  • the optical unit 22 of the intraocular lens 21 is disposed at a position closer to the rear side Rs than the equator of the lens capsule 34 (indicated by the alternate long and short dash line in the figure). . Therefore, a larger space is secured on the anterior capsule side of the optical unit 22. Therefore, the risk that the optical unit 22 contacts the iris is reduced.
  • the support portion 23 is formed of the same material, the cost can be significantly reduced compared to the case where this is a two-layer structure of different materials. Can do.
  • the flexible portion 25 of the support portion 23 is elastically deformed by receiving inward force due to contraction of the lens capsule 34.
  • the optical unit 22 is easily displaced to the rear side Rs.
  • the reason is that by forming the inclined surface 31 on the outer surface 26 of the flexible portion 25, the inward force applied to the flexible portion 25 when the lens capsule 34 contracts is more on the front side Fs than on the rear side Rs. Because it works hard. This means that a stronger force acts on the outer end surface 30 than the inclined surface 31 among the outer end surface 30 and the inclined surface 31 constituting the outer surface 26 of the flexible portion 25.
  • the outer end surface 30 in which the contact area of the main portion receiving the inward force among the outer surface 26 of the flexible portion 25 receiving the inward force due to the contraction of the lens capsule 34 is a part of the outer surface 26. Limited to For this reason, the force per unit area which the flexible part 25 receives by shrinkage
  • the optical portion 22 is not necessarily displaced, and the amount by which the optical portion 22 is displaced toward the posterior capsule 34b is very small. It becomes. That is, in the embodiment of the present invention, the optical unit 22 is slightly displaced toward the posterior capsule 34b or easily displaced by the balance of the forces of the front side Fs and the rear side Rs acting on the flexible portion 25. This reduces the risk of the optical part 22 coming into contact with the iris. For this reason, when the intraocular lens 21 is inserted into the crystalline lens capsule 34, the amount of displacement of the optical part 22 with respect to the thickness direction Z of the support part 23 can be minimized. Therefore, as compared with an intraocular lens intended to move the optical unit 22 to the posterior capsule side in the lens capsule 34, variation in the installation position of the optical unit 22 in the optical axis direction can be reduced.
  • Secondary cataract refers to a cataract that develops in months to years after surgery for inserting an intraocular lens.
  • the main cause of the occurrence of secondary cataract is that lens epithelial cells proliferate between the optical unit 22 and the posterior capsule 34b to cause turbidity.
  • the contact state between the optical unit 22 and the posterior capsule 34b is close, it is considered that the proliferation of the lens epithelial cells is suppressed and the risk of developing the subsequent cataract is reduced.
  • the inclined surface 31 does not necessarily have to be formed over the entire length of the flexible portion 25.
  • the inclined surface 31 is formed only in the portion that receives the force directly inward due to the contraction of the lens capsule 34, specifically, in the range where the flexible portion 25 directly contacts the equator portion of the lens capsule 34. May be.
  • the portion forming the inclined surface 31 on the outer surface 26 of the flexible portion 25 is the entire contact area where the flexible portion 25 contacts the contracting lens capsule 34. Even when the inclined surface 31 is formed at a ratio of 50% or more and less than 100% of the contact area, the above-described effects can be exhibited.
  • the cross-sectional shape of the flexible portion 25 in the direction orthogonal to the length direction Y of the support portion 23 is as shown in FIG. 3, but the present invention is not limited to this.
  • the cross-sectional shape of the flexible portion 25 described above may be a shape as shown in FIG. 6, FIG. 7, or FIG.
  • an outer surface 26 of the flexible portion 25 is constituted by an outer end surface 32 and a recessed surface 33 by forming a cutout portion 36 having an L-shaped cross section on the rear side Rs of the flexible portion 25. Yes.
  • the outer end surface 32 is formed to make a right angle with the front main surface 28.
  • the recessed surface 33 is formed in parallel with the outer end surface 32. Further, the recessed surface 33 is formed in a state of being recessed inward from the outer end surface 32 in the width direction X of the support portion 23.
  • the cross-sectional shape of the flexible portion 25 includes a round-shaped outer surface 26 that bulges outward, and the top position P3 of the outer surface 26 is greater than the center position P1 between the two main surfaces 28 and 29. Is also in a shape located on the front side Fs.
  • the top position P3 of the outer surface 26 refers to the position of the outermost Os in the width direction X of the support portion 23.
  • the rear side Rs of the outer surface 26 is formed in an inclined state so as to follow the shape of the posterior capsule side of the crystalline lens capsule 34.
  • the cross-sectional shape of the flexible portion 25 is a shape including an outer surface 26 that is obliquely curved from the outer end portion 28 a of the front main surface 28 toward the outer end portion 29 a of the rear main surface 29. .
  • the rear side Rs of the outer surface 26 is formed in a curved and inclined state so as to follow the shape of the posterior capsule side of the crystalline lens capsule 34.
  • the first shape example (FIG. 6), the second shape example (FIG. 7), and the third shape example (FIG. 8) described here are all of (1) to (3) described above. Corresponds to the shape.
  • the intraocular lens 21 provided with the support part 23 of the open loop shape was illustrated, even if applied to the intraocular lens provided with the support part of a closed loop shape not only this but Good.
  • the thickness dimension of the support part for obtaining a desired holding force is smaller than that of the intraocular lens having the support part having a closed loop shape. growing. For this reason, when this invention is applied to the intraocular lens 21 provided with the support part 23 of the open loop shape, a more remarkable effect is acquired at the point of installing the intraocular lens 21 stably.
  • the optical part 22 and the support part 23 were comprised with the same material (soft material), it is not restricted to this,
  • the optical part 22 is a soft material and the support part 23 is a hard material (for example, , Polymethyl methacrylate, etc.).
  • the optical part 22 and the base part 24 may be made of a soft material, and the flexible part 25 may be made of a hard material.

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PCT/JP2013/067458 2012-06-26 2013-06-26 Lentille intraoculaire Ceased WO2014003039A1 (fr)

Applications Claiming Priority (2)

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JP2012142733A JP5936461B2 (ja) 2012-06-26 2012-06-26 眼内レンズ
JP2012-142733 2012-06-26

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070088433A1 (en) * 2005-10-17 2007-04-19 Powervision Accommodating intraocular lens system utilizing direct force transfer from zonules and method of use
JP2007531605A (ja) * 2004-04-06 2007-11-08 グセレン ソシエテ アノニム 改良された眼球内のレンズ
JP2008534111A (ja) * 2005-03-30 2008-08-28 ニューレンズ・リミテッド 調節型眼内レンズ（ａｉｏｌ）アセンブリおよびそのための個別の構成要素
JP4689668B2 (ja) * 2005-05-20 2011-05-25 興和株式会社 眼内レンズ
WO2011068709A1 (fr) * 2009-12-01 2011-06-09 Alcon Research, Ltd. Lentille intraoculaire comprenant un bord concu pour reduire l'opacification de la capsule posterieure
WO2012006186A2 (fr) * 2010-06-29 2012-01-12 The Arizona Board Of Regents On Behalf Of The University Of Arizona Lentille intraoculaire accommodative comportant un matériau déformable
JP2013123615A (ja) * 2011-12-16 2013-06-24 Chukyo Medical Co Inc 眼内レンズ

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007531605A (ja) * 2004-04-06 2007-11-08 グセレン ソシエテ アノニム 改良された眼球内のレンズ
JP2008534111A (ja) * 2005-03-30 2008-08-28 ニューレンズ・リミテッド 調節型眼内レンズ（ａｉｏｌ）アセンブリおよびそのための個別の構成要素
JP4689668B2 (ja) * 2005-05-20 2011-05-25 興和株式会社 眼内レンズ
US20070088433A1 (en) * 2005-10-17 2007-04-19 Powervision Accommodating intraocular lens system utilizing direct force transfer from zonules and method of use
WO2011068709A1 (fr) * 2009-12-01 2011-06-09 Alcon Research, Ltd. Lentille intraoculaire comprenant un bord concu pour reduire l'opacification de la capsule posterieure
WO2012006186A2 (fr) * 2010-06-29 2012-01-12 The Arizona Board Of Regents On Behalf Of The University Of Arizona Lentille intraoculaire accommodative comportant un matériau déformable
JP2013123615A (ja) * 2011-12-16 2013-06-24 Chukyo Medical Co Inc 眼内レンズ

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