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WO2013119964A3 - Identification et enrichissement de sous-populations cellulaires - Google Patents

Identification et enrichissement de sous-populations cellulaires Download PDF

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Publication number
WO2013119964A3
WO2013119964A3 PCT/US2013/025361 US2013025361W WO2013119964A3 WO 2013119964 A3 WO2013119964 A3 WO 2013119964A3 US 2013025361 W US2013025361 W US 2013025361W WO 2013119964 A3 WO2013119964 A3 WO 2013119964A3
Authority
WO
WIPO (PCT)
Prior art keywords
enrichment
identification
cell subpopulations
subpopulations
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2013/025361
Other languages
English (en)
Other versions
WO2013119964A2 (fr
Inventor
Scott J. Dylla
Marianne Santaguida
Wade C. Anderson
Bob Y. LIU
Samuel A. WILLIAMS
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AbbVie Stemcentrx LLC
Original Assignee
Stemcentrx inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/369,277 external-priority patent/US20130061342A1/en
Priority claimed from US13/414,666 external-priority patent/US20130061340A1/en
Application filed by Stemcentrx inc filed Critical Stemcentrx inc
Publication of WO2013119964A2 publication Critical patent/WO2013119964A2/fr
Publication of WO2013119964A3 publication Critical patent/WO2013119964A3/fr
Priority to US14/454,107 priority Critical patent/US9778264B2/en
Anticipated expiration legal-status Critical
Priority to US15/698,839 priority patent/US20180067120A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C12N5/0695—Stem cells; Progenitor cells; Precursor cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00—Use of cells in diagnostics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La présente invention concerne des marqueurs pouvant être utilisés en vue de l'identification, de la caractérisation et, éventuellement, de l'enrichissement ou de l'isolement de sous-populations cellulaires ou de cellules oncogènes.
PCT/US2013/025361 2010-09-03 2013-02-08 Identification et enrichissement de sous-populations cellulaires Ceased WO2013119964A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US14/454,107 US9778264B2 (en) 2010-09-03 2014-08-07 Identification and enrichment of cell subpopulations
US15/698,839 US20180067120A1 (en) 2010-09-03 2017-09-08 Identification and enrichment of cell subpopulations

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US13/369,277 2012-02-08
US13/369,277 US20130061342A1 (en) 2011-09-02 2012-02-08 Identification and Enrichment of Cell Subpopulations
US13/414,666 2012-03-07
US13/414,666 US20130061340A1 (en) 2011-09-02 2012-03-07 Identification and Enrichment of Cell Subpopulations

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
US13/414,666 Continuation US20130061340A1 (en) 2010-09-03 2012-03-07 Identification and Enrichment of Cell Subpopulations
US201313820061A Continuation-In-Part 2010-09-03 2013-06-13

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US14/454,107 Continuation US9778264B2 (en) 2010-09-03 2014-08-07 Identification and enrichment of cell subpopulations

Publications (2)

Publication Number Publication Date
WO2013119964A2 WO2013119964A2 (fr) 2013-08-15
WO2013119964A3 true WO2013119964A3 (fr) 2013-11-28

Family

ID=47754997

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2013/025361 Ceased WO2013119964A2 (fr) 2010-09-03 2013-02-08 Identification et enrichissement de sous-populations cellulaires

Country Status (1)

Country Link
WO (1) WO2013119964A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106164672A (zh) * 2014-01-17 2016-11-23 麦诺米克国际有限公司 用于诊断的细胞表面前列腺癌抗原

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BR112013005116A2 (pt) 2010-09-03 2019-09-24 Stem Centrx Inc moduladores e métodos de uso
SG10201506767QA (en) 2010-09-03 2015-10-29 Stemcentrx Inc Identification and enrichment of cell subpopulations
US9778264B2 (en) 2010-09-03 2017-10-03 Abbvie Stemcentrx Llc Identification and enrichment of cell subpopulations
SG10201601792UA (en) 2010-12-08 2016-04-28 Stemcentrx Inc Novel modulators and methods of use
SA112330278B1 (ar) 2011-02-18 2015-10-09 ستيم سينتركس، انك. مواد ضابطة جديدة وطرق للاستخدام
US9534058B2 (en) 2012-02-08 2017-01-03 Abbvie Stemcentrx Llc Anti-CD324 monoclonal antibodies and uses thereof
KR20150003169A (ko) 2012-02-24 2015-01-08 스템 센트알엑스 인코포레이티드 Ｄｌｌ3 조절물질들 및 사용 방법
CA2865415C (fr) 2012-02-24 2022-06-21 Stem Centrx, Inc. Anticorps anti-sez6 et procedes d'utilisation associes
JP2016509014A (ja) 2013-02-08 2016-03-24 ステムセントリックス， インコーポレイテッド 新規の多特異的構成物
CN105164159A (zh) 2013-02-22 2015-12-16 施特姆森特克斯股份有限公司 新的抗体缀合物及其用途
MX377339B (es) 2013-08-28 2025-03-06 Abbvie Stemcentrx Llc Metodos de conjugacion de anticuerpos especificos de sitio y composiciones.
RU2016111139A (ru) 2013-08-28 2017-10-03 ЭББВИ СТЕМСЕНТРКС ЭлЭлСи Новые модуляторы sez6 и способы их применения
US9381205B2 (en) 2013-11-04 2016-07-05 Pfizer, Inc. Anti-EFNA4 antibody-drug conjugates
JP6515111B2 (ja) 2013-11-06 2019-05-22 アッヴィ・ステムセントルクス・エル・エル・シー 新規の抗クローディン抗体および使用方法
JP2017500028A (ja) 2013-12-12 2017-01-05 アッヴィ・ステムセントルクス・エル・エル・シー 新規の抗ｄｐｅｐ３抗体および使用方法
BR112016018891A2 (pt) 2014-02-21 2017-10-10 Abbvie Stemcentrx Llc anticorpos anti-dll3 e conjugados de fármacos para uso em melanoma
NZ725480A (en) 2014-04-30 2024-08-30 Pfizer Anti-ptk7 antibody-drug conjugates
TW201617368A (zh) 2014-09-05 2016-05-16 史坦森特瑞斯公司 新穎抗ｍｆｉ２抗體及使用方法
MA43342A (fr) * 2015-09-30 2018-08-08 Medimmune Ltd Compositions et procédé d'inhibition de cellules souches cancéreuses
AU2017254674A1 (en) 2016-04-21 2018-11-01 Abbvie Stemcentrx Llc Novel anti-BMPR1B antibodies and methods of use
WO2020033971A1 (fr) 2018-08-10 2020-02-13 New York University Utilisation de ligands agonistes du récepteur de l'igf-2 pour le traitement du syndrome d'angelman et de l'autisme

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106164672A (zh) * 2014-01-17 2016-11-23 麦诺米克国际有限公司 用于诊断的细胞表面前列腺癌抗原

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