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WO2013108361A1 - Système de mesure de la pression veineuse - Google Patents

Système de mesure de la pression veineuse Download PDF

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Publication number
WO2013108361A1
WO2013108361A1 PCT/JP2012/050807 JP2012050807W WO2013108361A1 WO 2013108361 A1 WO2013108361 A1 WO 2013108361A1 JP 2012050807 W JP2012050807 W JP 2012050807W WO 2013108361 A1 WO2013108361 A1 WO 2013108361A1
Authority
WO
WIPO (PCT)
Prior art keywords
pressure
pulse pressure
pulse
measuring device
measurement site
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2012/050807
Other languages
English (en)
Japanese (ja)
Inventor
神鳥　明彦
佑子 佐野
辻　敏夫
陽豊 平野
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hitachi Ltd
Original Assignee
Hitachi Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hitachi Ltd filed Critical Hitachi Ltd
Priority to PCT/JP2012/050807 priority Critical patent/WO2013108361A1/fr
Priority to JP2013554112A priority patent/JP5847202B2/ja
Publication of WO2013108361A1 publication Critical patent/WO2013108361A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6843—Monitoring or controlling sensor contact pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0247—Pressure sensors

Definitions

  • the present invention relates to a technique for measuring a subject's pulse pressure (maximum blood pressure, minimum blood pressure, difference between maximum blood pressure and minimum blood pressure).
  • Securing blood flow to the patient's brain is very important in emergency situations due to illness (brain diseases, etc.) and accidents (traffic accidents, etc.). Insufficient blood flow to the brain can leave serious sequelae in the patient's brain, even if lifesaving is successful. Whether or not the blood flow to the brain is sufficient can be determined mainly by the magnitude of the pulse pressure.
  • a doctor, a paramedic, or the like palpates the patient's carotid artery to determine whether the blood flow to the patient's brain is sufficient.
  • the pulse wave refers to a volume change caused by the movement of blood in the body tissue as a waveform from the body surface.
  • pulse waves can also be measured in the radial artery of the arm, and there is an increasing need for quantitative measurement of pulse strength and the like. This is known as pulse diagnosis in Chinese medicine, and it is said that the health status of the whole body can be grasped.
  • the present invention has been made in view of the above circumstances, and an object thereof is to stably measure a pulse pressure at a predetermined measurement site of a subject such as a patient.
  • the present invention is a pulse pressure measurement system for measuring a pulse pressure of a predetermined measurement site of a subject, and the measurement is performed so that the measurement site is recessed when measuring the pulse pressure.
  • a measurement device that is pressed against the measurement site by a person's finger, and a pulse pressure measurement device that measures the pulse pressure based on information from the measurement device, and the measurement device holds the finger of the measurement person
  • a finger holding unit that is arranged around the pressure sensor, a pressure sensor that outputs information on pressure applied to the measurement site by the force of the measurer's finger held by the finger holding unit,
  • An elastic body that is pressed around the measurement site when the pressure sensor is pressed against the measurement site by the force of the measurer's finger held by a holding unit, and the pulse pressure measuring device includes the Obtained from the measuring device Based on force information, as the pulse pressure, a processing unit that calculates at least one of a maximum value, a minimum value, and a difference between the maximum value and the minimum value in the pulse
  • the present invention it is possible to stably measure the pulse pressure at the measurement site of a subject such as a patient.
  • FIG. 1 is an overall configuration diagram of a pulse pressure measurement system according to an embodiment. It is a perspective view of the measuring apparatus of this embodiment. It is explanatory drawing of the operation principle of the measuring apparatus of this embodiment. It is a figure which shows the relationship between an output voltage and a pressure. It is a schematic diagram of the measuring apparatus of this embodiment, (a) represents the time when the blood vessel B is expanded, and (a) represents the time when the blood vessel B contracts. It is a figure which shows the relationship between a voltage difference and an output voltage. (A)-(d) is a figure which shows the relationship between an output voltage and blood pressure for every minimum voltage value, and those temporal changes.
  • (E)-(h) is a figure which shows the relationship between an output voltage and blood pressure for every minimum voltage value, and those temporal changes. It is a flowchart which shows the flow of the process by the pulse pressure measuring device of this embodiment.
  • (A)-(c) is a schematic diagram which shows the magnetic sensor and elastic body in the modification of the measuring apparatus of this embodiment.
  • a pulse pressure measurement system 1000 measures a pulse pressure (maximum blood pressure, minimum blood pressure, difference between maximum blood pressure and minimum blood pressure) at a predetermined measurement site of a subject.
  • the measuring device 1 and the pulse pressure measuring device 2 are provided.
  • the measuring apparatus 1 of FIG. 1 compared with the measuring apparatus 1 of FIG.
  • the measuring apparatus 1 includes a receiving coil 11 (magnetic field detecting means), a transmitting coil 12 (magnetic field generating means), a pressure sensor 13 (second pressure sensor), a spring 14, a holder 15 (finger holding unit), An elastic body 16, a pulse pressure detection unit 17, a lead wire 111, and a lead wire 121 are provided.
  • the receiving coil 11 and the transmitting coil 12 are collectively referred to as a magnetic sensor 19.
  • the magnetic sensor 19 is a pressure sensor that outputs information on the pressure applied to the measurement site of the subject (for example, a portion of the neck carotid artery) by the force of the finger of the measurer (doctor or the like) held by the holder 15. Specifically, voltage information according to the magnitude of pressure is output (details will be described later).
  • the receiving coil 11 is fixed to the upper surface of the inner space portion of the holder 15, and the transmitting coil 12 is attached to the lower surface of the inner space portion of the holder 15 via a spring 14.
  • the pressure sensor 13 is a sensor that is sandwiched between the holder 15 and the elastic body 16 and measures the pressure applied to the elastic body 16, and can be realized by, for example, a strain gauge.
  • the spring 14 is a spring having higher rigidity than the measurement site of the subject.
  • the holder 15 is a means for holding the measurer's finger.
  • the elastic body 16 is disposed around the pulse pressure detection unit 17 and is pressed around the measurement site when the pulse pressure detection unit 17 is pressed against the measurement site by the force of the finger of the measurer held by the holder 15. It is a member, and can be realized by, for example, rubber having rigidity higher than that of the measurement site.
  • the pulse pressure detection unit 17 is a means that is pressed against the measurement site by the force of the measurer's finger applied to the holder 15 so that the measurement site is recessed when measuring the pulse pressure, and is fixed to the transmission coil 12. That is, the transmission coil 12 and the pulse pressure detector 17 are interlocked.
  • the lead wire 111 has one end connected to the receiving coil 11 and the other end connected to the input / output circuit 21 of the pulse pressure measuring device 2.
  • One end of the lead wire 121 is connected to the transmitter coil 12, and the other end is connected to a drive circuit (not shown) of the measuring apparatus 1.
  • the receiving coil 11 and the transmitting coil 12 are arranged so as to face each other.
  • the human body H has a spring property and a damper property, since the spring property is more dominant, the human body H is approximately considered to be a spring having a predetermined spring constant. And it is necessary to select beforehand the spring 14 which has a spring constant larger than the spring constant of the human body H. FIG. Otherwise, when the force F is applied to the pulse pressure detector 17, the receiving coil 11 and the transmitting coil 12 come into contact with each other, and the role as the magnetic sensor 19 is impaired.
  • the AC oscillation source 31 generates an AC voltage having a specific frequency (for example, 20 kHz).
  • the alternating voltage is converted into an alternating current having a specific frequency by the amplifier 32, and the converted alternating current flows through the transmission coil 12.
  • the magnetic field generated by the alternating current flowing through the transmission coil 12 causes the reception coil 11 to generate an induced electromotive force.
  • the induced electromotive force increases as the distance D between the receiving coil 11 and the transmitting coil 12 decreases.
  • the alternating current generated in the receiving coil 11 by the induced electromotive force (the frequency is the same as the frequency of the alternating voltage generated by the alternating current oscillation source 31) is amplified by the preamplifier 33, and the amplified signal is input to the detection circuit 34.
  • the detection circuit 34 detects the amplified signal using the specific frequency or double frequency generated by the AC oscillation source 31. Therefore, the output of the AC oscillation source 31 is introduced as a reference signal 35 to the reference signal input terminal of the detection circuit 34. Further, an operation method using a full-wave rectifier circuit without using the detector circuit 34 may be adopted.
  • the voltage information (output signal) from the detection circuit 34 (or rectifier circuit) passes through the low-pass filter 36 and is then introduced into the processing unit 23 (see FIG. 1) of the pulse pressure measuring device 2.
  • FIG. Street The relationship between the pressure (force F) applied to the pulse pressure detection unit 17 (measurement site) and the magnitude of the voltage represented by the output signal introduced from the low-pass filter 36 to the processing unit 23 is shown in FIG. Street.
  • Such correspondence information between the magnitude of the voltage output from the magnetic sensor 19 and the magnitude of the pressure applied to the pulse pressure detection unit 17 is stored in advance in the storage unit 24 of the pulse pressure measuring device 2. . If the relationship between the output voltage and pressure shown in FIG. 4 is functionalized by a predetermined function, the least square method, or the like, the accuracy in converting the output voltage into pressure can be increased.
  • the pulse pressure measuring device 2 is a computer device that measures the pulse pressure at the measurement site of the subject based on information from the measuring device 1, and includes an input / output circuit 21, an input circuit 22, a processing unit 23, a storage unit 24, The sound generation unit 25, the display unit 26, the power supply unit 27, and the input unit 28 are provided.
  • the input / output circuit 21 processes the voltage information received from the receiving coil 11 of the measuring apparatus 1 as described above and transmits the information to the processing unit 23.
  • the input circuit 22 transmits information on the pressure received from the pressure sensor 13 of the measuring apparatus 1 to the processing unit 23.
  • the processing unit 23 is realized by, for example, a CPU (Central Processing Unit).
  • the processing unit 23 calculates the pressure applied to the pulse pressure detection unit 17 based on the voltage information acquired from the magnetic sensor 19 and the above-described correspondence information stored in the storage unit 24, and the pressure At least one of the maximum value, the minimum value, and the difference between the maximum value and the minimum value is calculated as pulse pressure (maximum blood pressure, minimum blood pressure, difference between maximum blood pressure and minimum blood pressure, respectively).
  • the processing unit 23 also calculates the average blood pressure of the measurement site of the subject, details of which will be described later.
  • the storage unit 24 is a means for storing various information, and is realized by, for example, a RAM (Random Access Memory), a ROM (Read Only Memory), an HDD (Hard Disk Drive), or the like.
  • a RAM Random Access Memory
  • ROM Read Only Memory
  • HDD Hard Disk Drive
  • the sound generator 25 is a means for generating sound, and is realized by a speaker, for example.
  • the sound generation unit 25 generates a beep sound at the start or end of the measurement by the measurement device 1 or gives the measurer a voice guidance for increasing or weakening the force to press the measurement device 1 against the measurement site. (Details will be described later).
  • the display unit 26 is a means for performing various displays, and is realized by, for example, an LCD (Liquid Crystal Display) or a CRT (Cathode Ray Tube) Display.
  • the display unit 26 displays a pulse pressure, an average blood pressure, an indicator visualizing the pulse pressure, and the like.
  • the power supply unit 27 is power supply means in the pulse pressure measuring device 2.
  • the input unit 28 is a means operated by the user for inputting various information, and is realized by, for example, a keyboard or a mouse.
  • the measuring device 1 when the measurer presses the measuring device 1 against the human body H with a predetermined force with the finger 40, when the blood vessel B expands, the elastic body 16 remains substantially stationary and the pulse pressure The detector 17 is pushed upward and moves, and the receiving coil 11 and the transmitting coil 12 approach each other.
  • the blood vessel B contracts, as shown in FIG. 5B, the elastic body 16 remains substantially stationary, the pulse pressure detector 17 moves downward, and the receiving coil 11 and the transmitting coil 12 move away.
  • the relationship between the strength of the force applied to the pulse pressure detector 17 and the accuracy of pulse pressure measurement will be described.
  • the force applied to the pulse pressure detector 17 becomes larger, the distance between the receiving coil 11 and the transmitting coil 12 becomes closer, and the output voltage from the receiving coil 11 becomes stronger.
  • the voltage difference As shown in FIG. 6, when the minimum output voltage is 1.4 V, the voltage difference is relatively small (see FIG. 7A (a)). In addition, the length of “I” vertically penetrating each dot in FIG. 6 indicates a standard deviation. When the lowest output voltage is 1.2V, the voltage difference is the largest (see FIG. 7A (b)). As the minimum output voltage decreases to 1.1V, 1V, 0.9V, 0.8V, and 0.7V, the voltage difference also decreases (FIGS. 7A (c), (d), 7B (e), (f ), (G)), when the minimum output voltage becomes 0.6 V, the voltage difference becomes zero (see FIG. 7B (h)).
  • the accuracy of pulse pressure measurement can be increased by pressing the measuring device 1 with an appropriate strength (the strength at which the minimum output voltage is 1 V to 1.2 V). Further, in principle, it is considered that the blood vessel B is most greatly waved up and down by pressing the measuring device 1 with a force about the average blood pressure.
  • step S1 the processing unit 23 determines whether or not measurement is started. If Yes, the process proceeds to step S2, and if No, the process returns to step S1.
  • the measurement may be determined to start when a predetermined operation is performed by the user at the input unit 28 of the pulse pressure measuring device 2, or When the output voltage from the receiving coil 11 exceeds a predetermined value, it may be determined that the measurement starts, or may be determined by another method.
  • step S2 the processing unit 23 determines whether the strength of pressing the measuring device 1 is strong, appropriate, or weak.
  • the determination in step S2 may be made based on a predetermined threshold, for example. Note that in order for the strength of the pressing force of the measuring device 1 to be “appropriate”, at least the pressure applied to the pulse pressure detection unit 17 needs to be within the range W in FIG. 4.
  • step S2 the processing after step S2 may be performed as follows. First, the processing unit 23 measures the pulse pressure and uses the voice generation unit 25 until the measured pulse pressure value does not increase any more. S2 ⁇ “weak”) voice guidance (step S3) that prompts to strengthen and when the pressing force is strong (step S2 ⁇ “strong”) voice guidance (step S4) that prompts weakening is repeated several times. return. Then, when it is determined that the measured pulse pressure value is maximum, it is determined as “appropriate” in step S2, and the process proceeds to step S5.
  • step S5 the processing unit 23 calculates the average blood pressure based on the pressure information acquired from the pressure sensor 13 as described above, and proceeds to step S6.
  • the value of the pressure acquired from the pressure sensor 13 may be used as the average blood pressure as it is, or the average blood pressure may be calculated by further performing a predetermined correction process.
  • step S ⁇ b> 6 the processing unit 23 calculates the pressure applied to the pulse pressure detection unit 17 based on the voltage information acquired from the magnetic sensor 19 and the correspondence information stored in the storage unit 24. Then, at least one of the maximum value, the minimum value, and the difference between the maximum value and the minimum value is calculated as a pulse pressure (omitted when already calculated in step S2), and the process proceeds to step S7.
  • step S7 the processing unit 23 displays the average blood pressure and the pulse pressure on the display unit 26, and ends the process.
  • the magnet 15 that outputs information on the voltage that correlates with the holder 15 that holds the finger of the measurer and the pressure that is pressed against the measurement site of the subject.
  • the measuring apparatus 1 that includes the sensor 19 and the elastic body 16 that is disposed around the magnetic sensor 19 and is pressed around the measurement site when the magnetic sensor 19 is pressed against the measurement site of the subject.
  • the magnetic sensor 19 can efficiently capture the fluctuation of the pulse wave at the measurement site of the subject and can stably measure the pulse pressure.
  • the measuring device 1 since the measuring device 1 has such a configuration, the measuring device 1 can be reduced in size so that it can be handled with one hand, and fingers can be easily attached to and detached from the measuring device 1.
  • the pulse pressure at the measurement site of the subject can be easily measured even in a narrow place.
  • the measuring device 1 is configured to hold the finger with the holder 15 and apply force to the measuring device 1 with the finger, so that the measurer can feel the pulse wave with the finger and realize high operability. it can.
  • the elastic body 16 is disposed around the pulse pressure detection unit 17, the blood vessel B is moderately pressed, the movement of the pulse wave at the measurement part contacting the pulse pressure detection unit 17 is increased, and the pulse pressure is increased. It can be measured with accuracy.
  • a method for measuring the pulse pressure for example, a method of converting the displacement of the body surface into an air pressure is also conceivable. Can not expect high accuracy.
  • the pressure itself generated on the body surface is converted into a displacement by the spring 14 and the displacement is magnetically measured. Measurement accuracy can be expected.
  • FIG. 9 shows only the number and relative positions of the elastic body 16 and the magnetic sensor 19.
  • the measuring apparatuses 1a and 1 three magnetic sensors 19 are provided, and an elastic body 16 is disposed so as to surround them.
  • the average of the voltages from the three magnetic sensors 19 is used, or only the information on the voltage having the highest voltage value among the three magnetic sensors 19 is used. , More accurate pulse pressure measurement can be performed.
  • the elastic bodies 16 are arranged so as to surround the respective magnetic sensors 19. In this way, by providing a plurality of magnetic sensors 19 and a plurality of elastic bodies 16, it is possible to firmly press the periphery of each magnetic sensor 19 at the measurement site of the subject, and to provide a more accurate pulse. Pressure measurement can be performed.
  • the holder 15 does not have to have a partially opened shape, and may have a substantially cylindrical finger sack shape, for example. If it does so, possibility that a finger will leave
  • the data when data is transmitted from the measuring device 1 to the pulse pressure measuring device 2 or when data is transmitted from the pulse pressure measuring device 2 to an external device (not shown), the data may be encrypted.
  • the elastic body 16 is circular, the outer diameter is 10 mm or less for carotid artery measurement, and the outer diameter is 3 mm or less for wrist radial artery measurement. It is desirable to match them.
  • only the pulse pressure may be calculated without using the pressure sensor 13 and calculating the average blood pressure.
  • specific configurations and processes can be appropriately changed without departing from the gist of the present invention.
  • Pulse pressure measuring device 11
  • Receiving coil (magnetic field detecting means) 12
  • Transmitting coil (magnetic field generating means) 13
  • Pressure sensor (second pressure sensor) 14
  • Spring 15 Holder (Finger holding part) 16
  • Elastic body 17
  • Pulse pressure detector 19
  • Magnetic sensor (pressure sensor) 21
  • Input / Output Circuit 22
  • Input Circuit 23
  • Processing Unit 24
  • Storage Unit 25
  • Sound Generation Unit 26
  • Display Unit Power Supply Unit
  • Input Unit 31
  • Amplifier 33 33
  • Preamplifier 34 Detection Circuit
  • Reference Signal 36
  • Low Pass Filter 40
  • Finger 111
  • Wire 121 Lead Line 1000
  • Pulse pressure measurement system B
  • Blood vessel H Human body

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physiology (AREA)
  • Vascular Medicine (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
PCT/JP2012/050807 2012-01-17 2012-01-17 Système de mesure de la pression veineuse Ceased WO2013108361A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PCT/JP2012/050807 WO2013108361A1 (fr) 2012-01-17 2012-01-17 Système de mesure de la pression veineuse
JP2013554112A JP5847202B2 (ja) 2012-01-17 2012-01-17 脈圧計測システム

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2012/050807 WO2013108361A1 (fr) 2012-01-17 2012-01-17 Système de mesure de la pression veineuse

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160150984A1 (en) * 2013-07-10 2016-06-02 Hitachi, Ltd. Sphygmomanometer system
KR101651501B1 (ko) * 2015-12-30 2016-08-29 주식회사 자원메디칼 혈압 측정 장치에서 자화를 방지하는 방법 및 장치
CN112401850A (zh) * 2020-12-04 2021-02-26 福州数据技术研究院有限公司 一种集成式指尖脉诊仪和系统

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RU2129459C1 (ru) * 1998-03-03 1999-04-27 Открытое акционерное общество "Машиностроительный завод "АРСЕНАЛ" Радиальный отстойник
KR102580267B1 (ko) 2018-01-18 2023-09-19 삼성전자주식회사 생체 신호 측정 장치

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JP2000005139A (ja) * 1998-06-23 2000-01-11 Seiko Epson Corp 脈波検出装置および触覚検出装置
JP2005516656A (ja) * 2002-02-05 2005-06-09 テンシス メディカル インコーポレイテッド パラメトリックスを使用して血行力学パラメータを非侵襲的に測定するための方法および装置
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JP2000005139A (ja) * 1998-06-23 2000-01-11 Seiko Epson Corp 脈波検出装置および触覚検出装置
JP2005516656A (ja) * 2002-02-05 2005-06-09 テンシス メディカル インコーポレイテッド パラメトリックスを使用して血行力学パラメータを非侵襲的に測定するための方法および装置
JP2006519045A (ja) * 2003-02-26 2006-08-24 コミツサリア　タ　レネルジー　アトミーク 血圧マイクロセンサ及び該血圧マイクロセンサを用いた測定機器
JP2006239114A (ja) * 2005-03-03 2006-09-14 Citizen Watch Co Ltd カフレス電子血圧計
JP2007054606A (ja) * 2005-07-26 2007-03-08 Matsushita Electric Works Ltd 生体信号検出装置

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160150984A1 (en) * 2013-07-10 2016-06-02 Hitachi, Ltd. Sphygmomanometer system
KR101651501B1 (ko) * 2015-12-30 2016-08-29 주식회사 자원메디칼 혈압 측정 장치에서 자화를 방지하는 방법 및 장치
CN112401850A (zh) * 2020-12-04 2021-02-26 福州数据技术研究院有限公司 一种集成式指尖脉诊仪和系统

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JP5847202B2 (ja) 2016-01-20

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