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WO2013179298A3 - Procédé pour la préparation d'un dérivé de phénylcarbamate et de formes polymorphes de celui-ci - Google Patents

Procédé pour la préparation d'un dérivé de phénylcarbamate et de formes polymorphes de celui-ci Download PDF

Info

Publication number
WO2013179298A3
WO2013179298A3 PCT/IN2013/000274 IN2013000274W WO2013179298A3 WO 2013179298 A3 WO2013179298 A3 WO 2013179298A3 IN 2013000274 W IN2013000274 W IN 2013000274W WO 2013179298 A3 WO2013179298 A3 WO 2013179298A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
polymorphic forms
phenyl carbamate
carbamate derivative
modification form
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IN2013/000274
Other languages
English (en)
Other versions
WO2013179298A2 (fr
Inventor
Shriprakash Dhar DWIVEDI
Jagdish Maganlal PATEL
Niraj Shyamlal Shah
Kishorkumar Maneklal Vinchhi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zydus Lifesciences Ltd
Original Assignee
Cadila Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cadila Healthcare Ltd filed Critical Cadila Healthcare Ltd
Publication of WO2013179298A2 publication Critical patent/WO2013179298A2/fr
Publication of WO2013179298A3 publication Critical patent/WO2013179298A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
    • C07C271/28—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La présente invention concerne une rétigabine stable qui comprend (d) un mélange de forme de modification cristalline A et de forme de modification B ; ou (e) un mélange de forme de modification cristalline A et de forme de modification C ; ou (f) un mélange de forme de modification cristalline B et de forme de modification C, le mélange de modification cristalline dans (a) ou (b) ou (c) n'étant pas converti en forme de modification cristalline A ou en forme de modification B ou en forme de modification C.
PCT/IN2013/000274 2012-04-23 2013-04-23 Procédé pour la préparation d'un dérivé de phénylcarbamate et de formes polymorphes de celui-ci Ceased WO2013179298A2 (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
IN1276MU2012 2012-04-23
IN1276/MUM/2012 2012-04-23
IN42MU2012 2012-05-05
IN42/MUM/2012 2012-05-05
IN391MU2013 2013-02-08
IN391/MUM/2013 2013-02-08

Publications (2)

Publication Number Publication Date
WO2013179298A2 WO2013179298A2 (fr) 2013-12-05
WO2013179298A3 true WO2013179298A3 (fr) 2014-02-20

Family

ID=49036621

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2013/000274 Ceased WO2013179298A2 (fr) 2012-04-23 2013-04-23 Procédé pour la préparation d'un dérivé de phénylcarbamate et de formes polymorphes de celui-ci

Country Status (1)

Country Link
WO (1) WO2013179298A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014179859A2 (fr) * 2013-05-08 2014-11-13 Apotex Inc. Forme polymorphe d'ezogabine et procédé de préparation de celle-ci
CN103724231A (zh) * 2014-01-27 2014-04-16 南京工业大学 一种瑞替加滨的合成方法
KR20230159506A (ko) * 2021-03-19 2023-11-21 자이자겐, 인크. Kv7 통로 개방제의 전구약물

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6538151B1 (en) * 1997-01-20 2003-03-25 Asta Medica Aktiengesellschaft Modifications of 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonylaminobenzene, and processes for their preparation
WO2013008250A2 (fr) * 2011-07-01 2013-01-17 Dr.Reddys Laboratories Limited. Forme cristalline de la rétigabine et procédés de mélange de variétés cristallines de la rétigabine

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6538151B1 (en) * 1997-01-20 2003-03-25 Asta Medica Aktiengesellschaft Modifications of 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonylaminobenzene, and processes for their preparation
WO2013008250A2 (fr) * 2011-07-01 2013-01-17 Dr.Reddys Laboratories Limited. Forme cristalline de la rétigabine et procédés de mélange de variétés cristallines de la rétigabine

Also Published As

Publication number Publication date
WO2013179298A2 (fr) 2013-12-05

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