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WO2013013439A1 - Bouchon de bouteille sans perforation et son procédé d'utilisation - Google Patents

Bouchon de bouteille sans perforation et son procédé d'utilisation Download PDF

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Publication number
WO2013013439A1
WO2013013439A1 PCT/CN2011/079360 CN2011079360W WO2013013439A1 WO 2013013439 A1 WO2013013439 A1 WO 2013013439A1 CN 2011079360 W CN2011079360 W CN 2011079360W WO 2013013439 A1 WO2013013439 A1 WO 2013013439A1
Authority
WO
WIPO (PCT)
Prior art keywords
syringe
infusion set
stopper
puncture
bottle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2011/079360
Other languages
English (en)
Chinese (zh)
Inventor
汪六一
汪金灿
李祖红
仲达
桂小芳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hainan Weikang Pharmaceutical Qianshan Co Ltd
Original Assignee
Hainan Weikang Pharmaceutical Qianshan Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hainan Weikang Pharmaceutical Qianshan Co Ltd filed Critical Hainan Weikang Pharmaceutical Qianshan Co Ltd
Priority to US13/638,556 priority Critical patent/US20130174937A1/en
Priority to KR1020127026030A priority patent/KR20130038827A/ko
Priority to AU2011362013A priority patent/AU2011362013B2/en
Priority to BR112013002508A priority patent/BR112013002508A2/pt
Priority to RU2013110758/15A priority patent/RU2013110758A/ru
Publication of WO2013013439A1 publication Critical patent/WO2013013439A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/04—Methods of, or means for, filling the material into the containers or receptacles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1406—Septums, pierceable membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1412—Containers with closing means, e.g. caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1475—Inlet or outlet ports
    • A61J1/1487—Inlet or outlet ports with friction fit, e.g. connecting tubes directly to a protruding port
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents

Definitions

  • the invention belongs to a packaging stopper for medicines, in particular to a puncture-free stopper; in addition, the invention relates to a method for using the puncture-free stopper.
  • Rubber stopper and rubber felt have the characteristics of low moisture absorption rate, good chemical property, good air tightness and no physiological side effects. They are especially suitable for sealing medicines. They are widely used in sealed glass vials, large infusion glass bottles and large infusions. Packaging of plastic bottles and plastic soft bags. The currently used plastic stoppers, rubber felts and rubber stoppers and rubber felts for large-sized bottles are all designed as a whole. Before clinical use, they must be puncture with a needle tip of a syringe or an infusion set and penetrate the rubber plug and rubber felt. In order to dispense medicine, use medicine, even in the course of one medication, it is necessary to puncture multiple times (often there are more than ten times of puncture).
  • the technical problem to be solved by the present invention is to provide a puncture-free bottle stopper, which overcomes the safety hazard of the puncture and chipping when the rubber or the felt is puncture in the injection package which is sealed with the rubber stopper or the rubber felt.
  • the present invention also provides a method of using the puncture-free stopper.
  • the invention provides a puncture-free stopper, comprising a stopper body and a cover for sealing the stopper body and the bottle mouth, wherein the bottle body is provided with a syringe or an infusion set suction joint passage.
  • the shape of the stopper body is designed into different geometric shapes according to different shapes of the bottle mouth; the stopper body is made of one or more of rubber, butyl rubber, halogenated butyl rubber, and plastic.
  • the cover for sealing the stopper body and the mouth of the bottle may be made of aluminum and/or plastic.
  • the stopper body is composed of an outer plug body and a downward flange, the flange is embedded in the bottle mouth; or the stopper body has a cylindrical shape and directly covers the bottle mouth.
  • the syringe or infusion set filler channel is designed in a variety of geometries depending on the shape of the syringe or infusion set.
  • the number of the syringe or infusion set suction joint passages is one or more; when the number of syringe or infusion set injection joint passages is one, the injection and aspiration solutions are all in the same joint passage; when the syringe or the infusion set is injected When the number of suction joint passages is plural, the injection and suction solutions are respectively from different joint passages.
  • the syringe or the infusion set injection connection channel is disposed in the middle of the stopper body, and runs through the entire stopper body from top to bottom; or the syringe or the infusion set injection connection channel is disposed at the upper part of the stopper body, and the lower part is provided There is a drug solution channel; or the syringe or infusion device injection port is provided in the middle of the bottle body, the upper part is provided with an insertion hole of a syringe or an infusion set, and the lower part is provided with a medical liquid channel capable of automatically opening and closing.
  • the syringe or infusion set filler channel is cylindrical, slitted or conical.
  • the syringe or infusion set injection fitting channel is open or closed.
  • the syringe or infusion set filler channel is closed, and an insertion mark is provided on the stopper body.
  • the present invention also provides a method for using the puncture-free stopper, comprising the following steps:
  • the syringe or infusion set is connected or inserted into the syringe or the infusion set inlet channel of the bottle body, and the drug solvent or drug solution can be injected into or withdrawn from the bottle through the syringe or the infusion device interface channel.
  • the puncture-free bottle stopper of the invention is suitable for sealing the bottle mouth with a rubber stopper or a rubber felt, and requires the medicine package to penetrate the bottle stopper injection solution.
  • the invention not only ensures the sealing effect of the rubber plug and the rubber felt, but also can directly connect the syringe or the infusion device into the syringe or the infusion set suction joint channel after opening the lid of the sealing stopper body and the bottle mouth.
  • the drug solvent or drug solution can be injected into the bottle through the drug injector or infusion device or sucked out from the bottle to avoid puncture, and no chipping due to puncture, thereby increasing the safety of the drug.
  • Embodiment 1A is a schematic structural view of Embodiment 1 of the puncture-free stopper of the present invention.
  • FIG. 1B is a schematic structural view of Embodiment 2 of the puncture-free stopper of the present invention.
  • Figure 2 is a schematic view showing the structure of the embodiment 3 of the puncture-free stopper of the present invention.
  • Figure 3 is a schematic view showing the structure of the puncture-free stopper of the present invention.
  • Figure 4 is a schematic view showing the structure of the puncture-free stopper of the fifth embodiment of the present invention.
  • Figure 5 is a schematic view showing the structure of the embodiment 6 of the puncture-free stopper of the present invention.
  • Figure 6 is a schematic view showing the structure of the embodiment 7 of the puncture-free stopper of the present invention.
  • Figure 7 is a schematic view showing the structure of the embodiment 8 of the puncture-free stopper of the present invention.
  • Figure 8 is a schematic view showing the structure of the puncture-free stopper of the present invention.
  • Figure 9 is a schematic view showing the overall structure of the puncture-free stopper of the present invention.
  • Fig. 10 is a schematic view showing another overall structure of the puncture-free stopper of the present invention.
  • the puncture-free stopper comprises a stopper body Y and a cover X for sealing the stopper body Y and the bottle mouth Z1 of the medicine bottle Z;
  • the stopper body Y may be composed of an outer plug body and a downward flange, the flange Embedded in the mouth Z1 (see Figure 9);
  • the stopper body Y can also be directly covered on the bottle mouth Z1 (the stopper body Y is cylindrical, no flange), and the cap X is used to seal the stopper body Y and the bottle Port Z1 (see Figure 10);
  • the syringe body Y is provided with a syringe or an infusion set.
  • the suction port can be in various forms, as described in the following examples.
  • the stopper body A is composed of an outer plug body 12 and a downward flange 13, and the flange 13 is embedded in the bottle mouth.
  • the stopper body A is provided with a slit-shaped syringe or an infusion set injection joint passage 11 in the middle, and a slit-shaped syringe or an infusion set injection joint passage 11 runs through the entire stopper body A, and the syringe or the infusion set injection joint passage 11 is closed, that is, after opening the aluminum stopper of the sealed stopper body A and the bottle mouth, the stopper body A does not expose the syringe or the infusion set injection joint passage 11 on the outer plug body 12 of the stopper body A.
  • a mark 14 which can be inserted into the syringe or the infusion set through the syringe or the infusion set cone (ie, the syringe or the infusion set). 11 to inject the liquid in the bottle.
  • the stopper body A has a cylindrical shape (without a flange) and directly covers the bottle mouth (the stopper body A is suitable for the puncture-free stopper overall structure shown in FIG. 10), and the stopper body A is in the middle.
  • a slit-shaped syringe or infusion set suction port passage 11 is provided, and a slit-shaped syringe or infusion set injection fitting passage 11 extends through the entire stopper body A, and the syringe or infusion set injection fitting passage 11 is closed.
  • the stopper body A does not expose the syringe or the infusion set injection joint passage 11, and the corresponding syringe or infusion set injection joint passage 11 on the stopper body A
  • the position is provided with a mark 14 into which a syringe or infusion set cone (i.e., a syringe or an infusion set) can be inserted to penetrate the syringe or infusion set port 11 to inject the solution.
  • the stopper body B is composed of an outer plug body 22 and a downward flange 23, and the flange 23 is embedded in the bottle mouth.
  • the upper part of the stopper body B is provided with a slit-shaped syringe or an infusion set suction joint passage 21, and a lower portion is provided with a chemical liquid passage 25, and the position of the chemical liquid passage 25 corresponds to a syringe or an infusion set injection joint passage 21, the syringe or
  • the infusion set injection port 21 is closed, that is, after opening the aluminum cap of the sealed stopper body B and the bottle mouth, the stopper body B does not expose the syringe or the infusion set suction port passage 21, in the stopper body B
  • the outer plug body 22 is provided with a mark 24 corresponding to the position of the syringe or the infusion set injection port 21, and the syringe or the infusion set cone can be inserted into the mark to penetrate the syringe or the infusion set channel 21 and the drug solution
  • the stopper body C is composed of an outer plug body 32 and a downward flange 33, and the flange 33 is embedded in the bottle mouth.
  • the middle of the stopper body C is provided with a conical syringe or an infusion set suction connection passage 35 (the conical shape is more convenient for the syringe or the infusion set cone to enter), and the upper part is provided with a syringe or an infusion set insertion hole 34 (the syringe or the infusion solution)
  • the position of the insertion hole 34 corresponds to the syringe or the infusion set suction port channel 35), and the lower portion is provided with the drug solution passage 31, which is closed.
  • the stopper body C does not expose the liquid medicine passage 31, and the syringe or the infusion set cone can be inserted from the syringe or the infusion set provided at the upper portion of the stopper body C.
  • the hole 34 is inserted through the syringe or the infusion set suction port channel 35 to open the drug solution channel 31 to inject the drug solution in the bottle.
  • the drug solution channel 31 is automatically closed when the syringe or infusion set cone is withdrawn from the stopper body C.
  • the stopper body D is composed of an outer plug body 42 and a downward flange 43, which is embedded in the mouth of the bottle.
  • a conical syringe or infusion set injection port 41 is provided in the middle of the stopper body D, and runs through the entire stopper body D from top to bottom; the syringe or the infusion set injection port passage 41 is open, that is, the seal is opened.
  • the stopper body D exposes the syringe or the infusion set suction joint passage 41, and the syringe or the infusion set cone can be directly placed into the syringe or the infusion set injection joint passage 41. Note the liquid medicine in the bottle.
  • the stopper body E is composed of an outer plug body 52 and a downward flange 53, which is embedded in the mouth of the bottle. There are two slit-shaped syringes or infusion set injection joint passages 511, 512 in the middle of the stopper body E.
  • Two slit-shaped syringes or infusion set injection joint passages 511, 512 extend through the entire stopper body E, two The slit-shaped syringe or the infusion set suction port passages 511, 512 are closed, that is, after opening the aluminum cap of the sealed stopper body E and the bottle mouth, the stopper body E does not expose the syringe or the infusion set
  • the joint passages 511, 512 are provided with marks 541, 542 on the outer plug body 52 of the stopper body E corresponding to the syringe or the infusion set suction joint passages 511, 512, and the syringe or the infusion set cone can be inserted into the mark 541, 542 can be inserted through the syringe or infusion set channel 511, 512 to inject or absorb the liquid medicine in the bottle, usually one of the two syringes or the infusion set injection port 511, 512 is used for injecting the drug solution, and the other is used for inject
  • the stopper body F is composed of an outer plug body 62 and a downward flange 63, and the flange 63 is embedded in the bottle mouth.
  • the upper part of the stopper body F is provided with two slit-shaped syringes or infusion set injection joint passages 611 and 612, and the lower part is provided with two chemical liquid passages 651 and 652, two chemical liquid passages 651 and 652 and two slits.
  • the position of the syringe or infusion set suction port channels 611, 612 corresponds; the two slit-shaped syringes or the infusion set injection port channels 611, 612 are closed, that is, the sealed stopper body F and the bottle opening are opened After the aluminum plastic cover, the stopper body F does not expose the syringe or infusion set injection joint passages 611, 612, and the position of the syringe or infusion set injection joint passages 611, 612 on the outer plug body 62 of the stopper body F Markers 641, 642 are provided, and the syringe or the infusion set cone can be inserted into the markers 641, 642 to penetrate the syringe or the infusion set suction channel 611, 612 and the drug solution channels 651, 652 to inject or absorb the liquid medicine in the bottle. Typically one of the two syringe or infusion set injection ports 611, 612 is used to inject the drug solution and the other is used to draw the drug solution.
  • the stopper body G is composed of an outer plug body 72 and a downward flange 73, and the flange 73 is embedded in the bottle mouth.
  • the middle of the stopper body G is provided with two conical syringes or infusion set injection joint passages 751, 752, and the upper portion is provided with a syringe or an infusion set insertion hole 741, 742 (the position of the syringe or the infusion set insertion holes 741, 742 is corresponding)
  • the syringe or the infusion set is filled with the suction passages 751, 752), and the lower portion is provided with two chemical liquid passages 711, 712, and the medical liquid passages 711, 712 are closed.
  • the syringe or the infusion set cone can be inserted into the syringe or the infusion set through the syringe or infusion set insertion holes 741, 742 provided in the upper part of the stopper body G.
  • the channels 751, 752 can open the drug solution channels 711, 712 to inject or absorb the liquid medicine in the bottle, and the drug solution channels 711, 712 are automatically closed when the syringe or the infusion set cone is pulled out from the bottle body G.
  • one of the two syringe or infusion set injection ports 751, 752 is used to inject the drug solution and the other is used to draw the drug solution.
  • the stopper body H is composed of an outer plug body 82 and a downward flange 83, and the flange 83 is embedded in the bottle mouth.
  • the conical body H is provided with two conical syringes or infusion set injection joint passages 811, 812, and runs through the entire stopper body H from top to bottom; the syringe or infusion set injection joint passages 811, 812 are open
  • the stopper body H exposes the syringe or the infusion set suction joint passages 811, 812, and the syringe or the infusion set cone can be directly placed into the syringe or
  • the infusion set is filled with the suction channel 811, 812 to inject or draw the liquid medicine in the bottle.
  • one of the two syringes or the infusion set injection port channels 811, 812 is used for injecting the liquid medicine, and the other is for sucking the liquid medicine
  • the stopper body of the embodiment 3-9 is configured in the manner of the syringe or the infusion set suction joint channel, and is also applicable to the method shown in FIG. Puncture-free stopper The overall structure.
  • the puncture-free bottle stopper of the invention is suitable for sealing the bottle mouth with a rubber stopper or a rubber felt, and requires the medicine package to penetrate the bottle stopper injection solution.
  • a rubber stopper or a rubber felt In use, after opening the lid of the sealed stopper body and the mouth of the bottle, expose the syringe or infusion set suction joint channel or its mark, connect the syringe or the infusion set cone to the syringe or the infusion set suction joint channel (not required).
  • the tip of the syringe or the infusion set is punctured into the entire stopper to produce the debris of the stopper material, and the drug solvent or the drug solution can be injected into the bottle through the drug injector or the infusion set or sucked out from the bottle to avoid puncture. Falling debris.
  • the puncture-free bottle stopper of the invention is suitable for sealing the bottle mouth with a rubber stopper or a rubber felt, and requires the medicine package to penetrate the bottle stopper injection solution.
  • the invention not only ensures the sealing effect of the rubber plug and the rubber felt, but also can directly connect the syringe or the infusion device into the syringe or the infusion set suction joint channel after opening the lid of the sealing stopper body and the bottle mouth.
  • the drug solvent or drug solution can be injected into the bottle through the drug injector or infusion device or sucked out from the bottle to avoid puncture, and no chipping due to puncture, thereby increasing the safety of the drug.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Closures For Containers (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La présente invention concerne un bouchon de bouteille sans perforation et son procédé d'utilisation. Le bouchon de bouteille a un corps principal de bouchon de bouteille (Y) et un couvercle (X) pour sceller de manière étanche ledit corps principal de bouchon de bouteille (Y) et l'embouchure de bouteille (Z1). Le corps principal de bouchon de bouteille (Y) comporte un canal d'infusion/aspiration en vue d'une liaison à un appareil d'injection ou de transfusion. Lors de l'utilisation, après retrait du couvercle (X) scellant de manière étanche le corps principal de bouchon de bouteille (Y) et l'embouchure de bouteille (Z1), l'appareil d'injection ou de transfusion peut être relié au canal d'infusion/aspiration ou introduit directement dans celui-ci, un solvant ou une solution de médicament peut alors être infusé dans la bouteille ou aspiré hors de la bouteille par ledit dispositif d'injection ou de transfusion, sans qu'une perforation ne soit requise. Le présent bouchon de bouteille sans perforation assure l'efficacité de scellement étanche du bouchon en caoutchouc et feutre de caoutchouc, et étant donné qu'il n'est pas produit de débris provoqués par une perforation, une plus grande sécurité est obtenue dans l'utilisation de médicaments.
PCT/CN2011/079360 2011-07-26 2011-09-06 Bouchon de bouteille sans perforation et son procédé d'utilisation Ceased WO2013013439A1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US13/638,556 US20130174937A1 (en) 2011-07-26 2011-09-06 Puncture Free Bottle Cork and the Application Thereof
KR1020127026030A KR20130038827A (ko) 2011-07-26 2011-09-06 주사침으로 찌르지 않는 병마개 및 그 사용방법
AU2011362013A AU2011362013B2 (en) 2011-07-26 2011-09-06 Puncture free bottle cork and the application thereof
BR112013002508A BR112013002508A2 (pt) 2011-07-26 2011-09-06 rolha livre de perfuração
RU2013110758/15A RU2013110758A (ru) 2011-07-26 2011-09-06 Беспрокольная бутылочная пробка и способ ее применения

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2011102108356A CN102389372A (zh) 2011-07-26 2011-07-26 免穿刺瓶塞及其使用方法
CN201110210835.6 2011-07-26

Publications (1)

Publication Number Publication Date
WO2013013439A1 true WO2013013439A1 (fr) 2013-01-31

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Application Number Title Priority Date Filing Date
PCT/CN2011/079360 Ceased WO2013013439A1 (fr) 2011-07-26 2011-09-06 Bouchon de bouteille sans perforation et son procédé d'utilisation

Country Status (7)

Country Link
US (1) US20130174937A1 (fr)
KR (1) KR20130038827A (fr)
CN (1) CN102389372A (fr)
AU (1) AU2011362013B2 (fr)
BR (1) BR112013002508A2 (fr)
RU (1) RU2013110758A (fr)
WO (1) WO2013013439A1 (fr)

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US10436336B2 (en) * 2014-11-13 2019-10-08 Charles Allen Cap with valve for inflation
CN104800077A (zh) * 2015-05-14 2015-07-29 威海联桥新材料科技股份有限公司 输液组合盖
CN107875014A (zh) * 2017-12-29 2018-04-06 潘林 一体成型无胶塞内封式软袋
CN109453023A (zh) * 2018-12-28 2019-03-12 山东亨洁医用包装科技有限公司 一种输液软袋用易撕膜双接口
JP2023055590A (ja) * 2021-10-06 2023-04-18 有限会社米田精密金型製作所 容器の蓋体
KR102678636B1 (ko) * 2022-03-29 2024-06-26 주식회사 지투이 펜타입 인슐린카트리지
KR102678640B1 (ko) * 2022-03-29 2024-06-26 주식회사 지투이 펜타입 인슐린카트리지

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2488501Y (zh) * 2001-07-21 2002-05-01 黄建文 单侧开关式医用橡胶瓶塞
CN200963343Y (zh) * 2006-11-07 2007-10-24 孙百华 单向活瓣式医用橡胶瓶塞
CN102283776A (zh) * 2011-07-07 2011-12-21 海南卫康制药(潜山)有限公司 免穿刺瓶塞及其使用方法
CN202161571U (zh) * 2011-07-07 2012-03-14 海南卫康制药(潜山)有限公司 免穿刺瓶塞

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1180665A (en) * 1915-11-29 1916-04-25 Randall Faichney Company Inc Closure or stopper for serum-containers, &c.
US1189465A (en) * 1916-01-24 1916-07-04 Abbott Lab Container for hypodermic solutions.
US1413703A (en) * 1918-12-07 1922-04-25 Abbott Lab Closure for hypodermic-solution containers
US1375471A (en) * 1919-10-17 1921-04-19 Arthur G Sherman Bottle-stopper
US1740717A (en) * 1927-09-26 1929-12-24 Antidolor Mfg Co Inc Medicament container
US2072853A (en) * 1934-12-01 1937-03-09 Donald E Baxter Closure
US2153981A (en) * 1936-04-03 1939-04-11 Winthrop Chem Co Inc Medicinal container
US2135386A (en) * 1937-06-18 1938-11-01 Phoenix Metal Cap Co Inc Closure for containers
US2231418A (en) * 1940-03-02 1941-02-11 Lilly Co Eli Liquid-administering apparatus
US2421313A (en) * 1941-12-12 1947-05-27 Baxter Laboratories Inc Closure for containers
US2579724A (en) * 1946-04-15 1951-12-25 Breakstone Seymour Valved closure plug for insertion in the neck of a bottle
US2906423A (en) * 1956-07-18 1959-09-29 American Cyanamid Co Closure puncturable by polyethylene needle
US3653528A (en) * 1970-03-03 1972-04-04 West Co Stopper for medicament flasks
US3823840A (en) * 1972-08-04 1974-07-16 Silver J Prepunctured closure
US4244478A (en) * 1979-06-27 1981-01-13 Mpl, Inc. Closure assembly for unit dose vial
US4265242A (en) * 1979-07-23 1981-05-05 Cohen Milton J Filter device for injectable fluid
US5215537A (en) * 1990-09-13 1993-06-01 Lynn Lawrence A Septum for a blunt cannula
DE4112209A1 (de) * 1991-04-13 1992-10-15 Behringwerke Ag Behaelterverschluss mit durchstossbarem verschlusskoerper
JPH08500036A (ja) * 1992-08-07 1996-01-09 ザ・ウエスト・カンパニー・インコーポレーテッド ニードルレス型のアクセスストッパ
PT675830E (pt) * 1992-12-30 2000-07-31 Abbott Lab Rolha de diafragma fino e dispositivo de penetracao rombo
US5328041A (en) * 1993-06-30 1994-07-12 Abbott Laboratories Two piece stopper for blunt fluid connector
ATE176860T1 (de) * 1993-12-28 1999-03-15 Abbott Lab Wiederverschliessbarer verschluss für flüssigkeitsöffnung
WO2002036182A2 (fr) * 2000-11-03 2002-05-10 Chromatography Research Supplies, Inc. Septum a chanfrein et pre-perforation lineaire

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2488501Y (zh) * 2001-07-21 2002-05-01 黄建文 单侧开关式医用橡胶瓶塞
CN200963343Y (zh) * 2006-11-07 2007-10-24 孙百华 单向活瓣式医用橡胶瓶塞
CN102283776A (zh) * 2011-07-07 2011-12-21 海南卫康制药(潜山)有限公司 免穿刺瓶塞及其使用方法
CN202161571U (zh) * 2011-07-07 2012-03-14 海南卫康制药(潜山)有限公司 免穿刺瓶塞

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BR112013002508A2 (pt) 2017-12-12
KR20130038827A (ko) 2013-04-18
AU2011362013B2 (en) 2014-05-08
AU2011362013A1 (en) 2013-02-14
US20130174937A1 (en) 2013-07-11
CN102389372A (zh) 2012-03-28

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