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WO2013058578A3 - System for screening skin-whitening material - Google Patents

System for screening skin-whitening material Download PDF

Info

Publication number
WO2013058578A3
WO2013058578A3 PCT/KR2012/008555 KR2012008555W WO2013058578A3 WO 2013058578 A3 WO2013058578 A3 WO 2013058578A3 KR 2012008555 W KR2012008555 W KR 2012008555W WO 2013058578 A3 WO2013058578 A3 WO 2013058578A3
Authority
WO
WIPO (PCT)
Prior art keywords
skin
whitening material
screening
whitening
screening skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2012/008555
Other languages
French (fr)
Korean (ko)
Other versions
WO2013058578A2 (en
Inventor
이애영
이태룡
최현정
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amorepacific Corp
Industry Academic Cooperation Foundation of Dongguk University
Original Assignee
Amorepacific Corp
Industry Academic Cooperation Foundation of Dongguk University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020120114965A external-priority patent/KR102031161B1/en
Application filed by Amorepacific Corp, Industry Academic Cooperation Foundation of Dongguk University filed Critical Amorepacific Corp
Priority to JP2014536989A priority Critical patent/JP6069334B2/en
Priority to CN201280051510.0A priority patent/CN103857802B/en
Publication of WO2013058578A2 publication Critical patent/WO2013058578A2/en
Publication of WO2013058578A3 publication Critical patent/WO2013058578A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C12N5/0698—Skin equivalents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
    • C12N2502/091—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells melanocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
    • C12N2502/094—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323—Adult fibroblasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00—Use of cells in diagnostics
    • C12N2503/04—Screening or testing on artificial tissues
    • C12N2503/06—Screening or testing on artificial skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Birds (AREA)
  • Cosmetics (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Disclosed are a system for screening a skin-whitening material comprising one or more layers which include one or more cells of fibroblasts, keratinocytes, and melanocytes, and a method for screening a skin-whitening material using the system. In addition, the invention presents a composition for skin whitening which comprises a material screened by the method for screening a skin- whitening material as an active ingredient.
PCT/KR2012/008555 2011-10-18 2012-10-18 System for screening skin-whitening material Ceased WO2013058578A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2014536989A JP6069334B2 (en) 2011-10-18 2012-10-18 Skin whitening substance screening structure
CN201280051510.0A CN103857802B (en) 2011-10-18 2012-10-18 Skin-whitening screening substances system

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR10-2011-0106614 2011-10-18
KR20110106614 2011-10-18
KR1020120114965A KR102031161B1 (en) 2011-10-18 2012-10-16 Screening System of candidate material for skin-whitening
KR10-2012-0114965 2012-10-16

Publications (2)

Publication Number Publication Date
WO2013058578A2 WO2013058578A2 (en) 2013-04-25
WO2013058578A3 true WO2013058578A3 (en) 2013-07-04

Family

ID=48141546

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2012/008555 Ceased WO2013058578A2 (en) 2011-10-18 2012-10-18 System for screening skin-whitening material

Country Status (1)

Country Link
WO (1) WO2013058578A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102212623B1 (en) * 2014-04-16 2021-02-09 (주)아모레퍼시픽 Skin-improving material controlling expression of cadherin11 or N-cadherin and method for screening the material
JP6320833B2 (en) * 2014-04-21 2018-05-09 日本メナード化粧品株式会社 Screening method for whitening ingredients

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008125872A1 (en) * 2007-04-17 2008-10-23 Renovo Limited Wif-1 for accelerating wound healing
US20090123401A1 (en) * 2006-04-25 2009-05-14 Shiseido Company, Ltd. Method of Predicting Spot Formation on the Skin Using Spot Site-Accelerating Genes as an Indicator Thereof and Method of Screening Inhibitors of Spot Formation on the Skin
KR20100039077A (en) * 2008-10-07 2010-04-15 숙명여자대학교산학협력단 Screening system using ndrg2 as a novel regulator gene of pigmentation in developing agents for application of skin hyper-pigmentation treatment
US20100317590A1 (en) * 2006-12-07 2010-12-16 Vincent Hearing Regulation of skin characteristics by dickkopf1 (dkk1)

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090123401A1 (en) * 2006-04-25 2009-05-14 Shiseido Company, Ltd. Method of Predicting Spot Formation on the Skin Using Spot Site-Accelerating Genes as an Indicator Thereof and Method of Screening Inhibitors of Spot Formation on the Skin
US20100317590A1 (en) * 2006-12-07 2010-12-16 Vincent Hearing Regulation of skin characteristics by dickkopf1 (dkk1)
WO2008125872A1 (en) * 2007-04-17 2008-10-23 Renovo Limited Wif-1 for accelerating wound healing
KR20100039077A (en) * 2008-10-07 2010-04-15 숙명여자대학교산학협력단 Screening system using ndrg2 as a novel regulator gene of pigmentation in developing agents for application of skin hyper-pigmentation treatment

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DUBERTRET L. ET AL.: "Reconstruction of the human skin equivalent in vitro: a new tool for skin biology", SKIN PHAMACOL., vol. 3, no. 2, 1990, pages 144 - 148 *

Also Published As

Publication number Publication date
WO2013058578A2 (en) 2013-04-25

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