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WO2013144727A3 - A scaffold material graft for wound care and/or other tissue healing applications - Google Patents

A scaffold material graft for wound care and/or other tissue healing applications Download PDF

Info

Publication number
WO2013144727A3
WO2013144727A3 PCT/IB2013/001233 IB2013001233W WO2013144727A3 WO 2013144727 A3 WO2013144727 A3 WO 2013144727A3 IB 2013001233 W IB2013001233 W IB 2013001233W WO 2013144727 A3 WO2013144727 A3 WO 2013144727A3
Authority
WO
WIPO (PCT)
Prior art keywords
scaffold material
wound care
tissue healing
healing applications
material graft
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2013/001233
Other languages
French (fr)
Other versions
WO2013144727A2 (en
Inventor
Gudmundur Fertram Sigurjonsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kerecis ehf
Original Assignee
Kerecis ehf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kerecis ehf filed Critical Kerecis ehf
Publication of WO2013144727A2 publication Critical patent/WO2013144727A2/en
Publication of WO2013144727A3 publication Critical patent/WO2013144727A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/04—Non-resorbable materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0047—Specific proteins or polypeptides not covered by groups A61L26/0033 - A61L26/0042
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0057—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/005—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/043—Proteins; Polypeptides; Degradation products thereof
    • A61L31/047—Other specific proteins or polypeptides not covered by A61L31/044 - A61L31/046

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Transplantation (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)

Abstract

A scaffold material for wound care and/or other tissue healing applications. The scaffold material includes a decellularized extracellular matrix from fish skin. The scaffold material may also include lipids from the lipid layer of the fish skin. The scaffold material may also include viable cells (e.g., fibroblasts and/or keratinocytes) within the scaffold material. Methods for making and using the scaffold material are also described.
PCT/IB2013/001233 2012-03-30 2013-03-29 A scaffold material graft for wound care and/or other tissue healing applications Ceased WO2013144727A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261617916P 2012-03-30 2012-03-30
US61/617,916 2012-03-30

Publications (2)

Publication Number Publication Date
WO2013144727A2 WO2013144727A2 (en) 2013-10-03
WO2013144727A3 true WO2013144727A3 (en) 2013-11-28

Family

ID=48877282

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2013/001233 Ceased WO2013144727A2 (en) 2012-03-30 2013-03-29 A scaffold material graft for wound care and/or other tissue healing applications

Country Status (1)

Country Link
WO (1) WO2013144727A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL244798A0 (en) * 2015-03-31 2016-07-31 Body Organ Biomedical Corp Tissue repair material derived from fish skin and manufacturing method thereof
BR102015021435B8 (en) * 2015-09-03 2023-11-07 Companhia Energetica Do Ceara Process of processing tilapia skin and its use in covering skin lesions
CN108355172A (en) * 2018-04-17 2018-08-03 上海市第六人民医院 A kind of soft tissue repair bionical matrix of de- cell Java tilapia skin and its preparation method and application
CN108478869A (en) * 2018-04-17 2018-09-04 上海市第六人民医院 A kind of Regeneration and Repair bionical matrix of de- cell black carp skin and its preparation method and application
CA3116899A1 (en) * 2018-10-24 2020-04-30 Somnio Global Holdings, Llc Functional wound healing dressings
BR102018073515A2 (en) * 2018-11-14 2020-05-26 Edmar Maciel Lima Junior process of obtaining extracellular matrix of tilapia skin (oreochromis niloticus) and use of extracellular matrix of tilapia
BR102018073510A2 (en) * 2018-11-14 2020-05-26 Edmar Maciel Lima Junior process of obtaining lyophilized tilapia skin and use of lyophilized tilapia skin
PE20242340A1 (en) * 2021-03-24 2024-12-12 Kerecis Hf A COLORED BIOLOGICAL WOUND TREATMENT THAT PROVIDES MONITORING OF HEALING PROGRESS
CN119053996A (en) * 2022-03-25 2024-11-29 凯瑞希斯有限责任公司 Systems, devices, and methods for identifying defects in medical implant procedures
CN114990095B (en) * 2022-06-28 2024-05-24 天津天隆江大生物科技有限公司 Complex enzyme preparation for producing antifreeze protein polypeptide and application thereof
EP4609885A1 (en) * 2022-11-22 2025-09-03 Suzhou Microport Regenerative Medicine Technology Co. Ltd Biological patch, preparation method therefor, and use thereof
CN116650723B (en) * 2023-07-06 2025-09-16 苏州微创再生医学科技有限公司 Fish skin-based biological patch, preparation method thereof and medical material

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4801299A (en) * 1983-06-10 1989-01-31 University Patents, Inc. Body implants of extracellular matrix and means and methods of making and using such implants
EP0753313A1 (en) * 1995-06-26 1997-01-15 Hokkaido Government Skin substitute using marine organisms
US20090036656A1 (en) * 2007-07-31 2009-02-05 Body Organ Biomedical Corp. Method for preparing a biomaterial
WO2011042794A2 (en) * 2009-10-07 2011-04-14 Kerecis Ehf A scaffold material for wound care and/or other tissue healing applications

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1068703A (en) 1991-07-25 1993-02-10 王权海 Method for preparing fish skin for external application to burn
FR2809412A1 (en) 2000-05-26 2001-11-30 Coletica Use of aquatic collagen for making supports for tissue engineering, particularly skin or tissue equivalents for surgical repair, studying aging processes and screening
US20030059460A1 (en) 2001-09-27 2003-03-27 Yasuhiko Tabata Hybrid material for regeneration of living body tissue

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4801299A (en) * 1983-06-10 1989-01-31 University Patents, Inc. Body implants of extracellular matrix and means and methods of making and using such implants
EP0753313A1 (en) * 1995-06-26 1997-01-15 Hokkaido Government Skin substitute using marine organisms
US20090036656A1 (en) * 2007-07-31 2009-02-05 Body Organ Biomedical Corp. Method for preparing a biomaterial
WO2011042794A2 (en) * 2009-10-07 2011-04-14 Kerecis Ehf A scaffold material for wound care and/or other tissue healing applications

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BOTTINO M C ET AL: "Freeze-dried acellular dermal matrix graft: Effects of rehydration on physical, chemical, and mechanical properties", DENTAL MATERIALS, ELSEVIER, AMSTERDAM, NL, vol. 25, no. 9, 1 September 2009 (2009-09-01), pages 1109 - 1115, XP026391587, ISSN: 0109-5641, [retrieved on 20090424] *
DAHMS S E ET AL: "Composition and biomechanical properties of the bladder acellular matrix graft: comparative analysis in rat, pig and human", BRITISH JOURNAL OF UROLOGY,, vol. 82, 5 May 1998 (1998-05-05), pages 411 - 419, XP002626601 *
MANSBRIDGE J: "SKIN SUBSTITUTES TO ENHANCE WOUND HEALING", EXPERT OPINION ON INVESTIGATIONAL DRUGS, ASHLEY PUBLICATIONS LTD., LONDON, GB, vol. 7, no. 5, 1 May 1998 (1998-05-01), pages 803 - 809, XP000971597, ISSN: 1354-3784, DOI: 10.1517/13543784.7.5.803 *
SONG E ET AL: "Collagen scaffolds derived from a marine source and their biocompatibility", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 27, no. 15, 1 May 2006 (2006-05-01), pages 2951 - 2961, XP025097265, ISSN: 0142-9612, [retrieved on 20060501], DOI: 10.1016/J.BIOMATERIALS.2006.01.015 *
TOSHIYUKI IKOMA ET AL: "Physical properties of type I collagen extracted from fish scales of Pagrus major and Oreochromis niloticas", INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, ELSEVIER BV, NL, vol. 32, no. 3-5, 1 September 2003 (2003-09-01), pages 199 - 204, XP002626600, ISSN: 0141-8130, [retrieved on 20030719], DOI: 10.1016/S0141-8130(03)00054-0 *
YEH M I ET AL: "A NOVEL NATIVE MATRIX FOR TISSUE ENGINEERING. ANALYSIS OF CELL-MATRIX INTERACTION", FASEB JOURNAL, FED. OF AMERICAN SOC. FOR EXPERIMENTAL BIOLOGY, US, vol. 14, no. 4, 15 March 2000 (2000-03-15), pages A444, XP000982329, ISSN: 0892-6638 *

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