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WO2013043011A3 - 갈화 추출물을 유효성분으로 함유하는 자궁내막증의 예방 및 치료용 약학적 조성물 - Google Patents

갈화 추출물을 유효성분으로 함유하는 자궁내막증의 예방 및 치료용 약학적 조성물 Download PDF

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Publication number
WO2013043011A3
WO2013043011A3 PCT/KR2012/007653 KR2012007653W WO2013043011A3 WO 2013043011 A3 WO2013043011 A3 WO 2013043011A3 KR 2012007653 W KR2012007653 W KR 2012007653W WO 2013043011 A3 WO2013043011 A3 WO 2013043011A3
Authority
WO
WIPO (PCT)
Prior art keywords
preventing
pharmaceutical composition
active ingredients
treating endometriosis
composition containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2012/007653
Other languages
English (en)
French (fr)
Other versions
WO2013043011A2 (ko
Inventor
최정혜
김지현
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyung Hee University
Original Assignee
Kyung Hee University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyung Hee University filed Critical Kyung Hee University
Priority to EP12833704.5A priority Critical patent/EP2762147B1/en
Priority to US14/346,667 priority patent/US9504724B2/en
Publication of WO2013043011A2 publication Critical patent/WO2013043011A2/ko
Publication of WO2013043011A3 publication Critical patent/WO2013043011A3/ko
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488—Pueraria (kudzu)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

본 발명은 갈화(Puerariae Flos) 추출물을 유효성분으로 함유하는 자궁내막증 및 이의 합병증의 예방 또는 치료용 약학적 조성물에 관한 것으로, 더욱 구체적으로는 갈화(Puerariae Flos) 추출물은 자궁내막증 세포의 이동 및 부착을 억제하고, 이동 및 부착 관련 인자인 MMP-2 및 MMP-9의 발현을 억제하고, 통증 관련 인자인 COX-2의 발현을 억제하고, 염증 관련 사이토카인인 MCP-1 및 RANTES의 발현을 억제하는 활성을 가짐으로써 자궁내막증 및 이의 합병증의 예방 또는 치료용 약학적 조성물, 및 건강식품의 유효성분으로 유용하게 사용될 수 있다.
PCT/KR2012/007653 2011-09-23 2012-09-24 갈화 추출물을 유효성분으로 함유하는 자궁내막증의 예방 및 치료용 약학적 조성물 Ceased WO2013043011A2 (ko)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP12833704.5A EP2762147B1 (en) 2011-09-23 2012-09-24 Pharmaceutical composition containing puerariae flos extracts as active ingredients for preventing and treating endometriosis
US14/346,667 US9504724B2 (en) 2011-09-23 2012-09-24 Pharmaceutical composition comprising extract of Puerariae flos for prevention and treatment of endometriosis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2011-0096323 2011-09-23
KR1020110096323A KR101357119B1 (ko) 2011-09-23 2011-09-23 갈화 추출물을 유효성분으로 함유하는 자궁내막증의 예방 및 치료용 약학적 조성물

Publications (2)

Publication Number Publication Date
WO2013043011A2 WO2013043011A2 (ko) 2013-03-28
WO2013043011A3 true WO2013043011A3 (ko) 2013-05-23

Family

ID=47915042

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2012/007653 Ceased WO2013043011A2 (ko) 2011-09-23 2012-09-24 갈화 추출물을 유효성분으로 함유하는 자궁내막증의 예방 및 치료용 약학적 조성물

Country Status (4)

Country Link
US (1) US9504724B2 (ko)
EP (1) EP2762147B1 (ko)
KR (1) KR101357119B1 (ko)
WO (1) WO2013043011A2 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101693573B1 (ko) * 2015-05-08 2017-01-06 경희대학교 산학협력단 갱년기 증상의 예방 또는 치료 효과가 있는 약제학적 조성물 및 그 제조방법
KR102233990B1 (ko) 2019-01-24 2021-03-30 건양대학교 산학협력단 유레아플라즈마 유레아리티쿰 감염을 통한 자궁내막증 동물 모델 개발
KR102767886B1 (ko) * 2020-03-19 2025-02-18 주식회사 엘지생활건강 카칼라이드를 포함하는 조성물

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20050038853A (ko) * 2003-10-23 2005-04-29 학교법인 상지학원 항염증 활성을 갖는 해동피, 갈화, 옻나무 추출물을함유하는 조성물
KR100540788B1 (ko) * 2005-05-24 2006-01-10 롯데제과주식회사 갈화 추출물을 함유하는 건강식품
KR100547560B1 (ko) * 2005-08-29 2006-01-31 학교법인 상지학원 항염증 활성을 갖는 해동피, 갈화, 옻나무 추출물을함유하는 약학조성물
KR100552995B1 (ko) * 2003-04-17 2006-02-16 롯데제과주식회사 뇌기능 개선 효과가 있는 갈화 추출물 및 이의 제조방법
WO2007110241A1 (en) * 2006-03-29 2007-10-04 G.I.M.-Gesellschaft Für Innovative Medizin G.M.B.H. Nfg Ohg Plant extracts, plant components and the uses thereof
WO2009033103A1 (en) * 2007-09-07 2009-03-12 Bionovo, Inc. Estrogenic extracts of pueraria lobata willd, ohwi of the leguminosae family and uses thereof
KR100950564B1 (ko) * 2008-03-03 2010-04-01 동아대학교 산학협력단 한약재 추출물을 유효성분으로 함유하는 항암용 조성물

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1057936C (zh) * 1995-04-20 2000-11-01 裴玉环 治子宫内膜异位症的中药“内异散”及制作工艺
JP2008214191A (ja) * 2005-04-27 2008-09-18 Toyo Shinyaku:Kk 肝中脂質蓄積抑制剤
ITMI20051049A1 (it) * 2005-06-07 2006-12-08 Marfarma Holding S P A "composizioni a base di estratti fitroestrogenici per il trattamento dela sindrome menopausale e pre-mestruale e dell'ipertrofia prostatica benigna"
JP2009126853A (ja) * 2007-11-27 2009-06-11 Tsujido Kagaku Kk 治療剤
CN101670064A (zh) * 2008-09-11 2010-03-17 北京天科仁祥医药科技有限公司 一种用于治疗子宫内膜异位症的复方中药
CN101966301A (zh) * 2010-07-13 2011-02-09 泰一和浦（北京）中医药研究院有限公司 一种治疗盆腔炎的中药组合物及其制备方法

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* Cited by examiner, † Cited by third party
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KR100552995B1 (ko) * 2003-04-17 2006-02-16 롯데제과주식회사 뇌기능 개선 효과가 있는 갈화 추출물 및 이의 제조방법
KR20050038853A (ko) * 2003-10-23 2005-04-29 학교법인 상지학원 항염증 활성을 갖는 해동피, 갈화, 옻나무 추출물을함유하는 조성물
KR100540788B1 (ko) * 2005-05-24 2006-01-10 롯데제과주식회사 갈화 추출물을 함유하는 건강식품
KR100547560B1 (ko) * 2005-08-29 2006-01-31 학교법인 상지학원 항염증 활성을 갖는 해동피, 갈화, 옻나무 추출물을함유하는 약학조성물
WO2007110241A1 (en) * 2006-03-29 2007-10-04 G.I.M.-Gesellschaft Für Innovative Medizin G.M.B.H. Nfg Ohg Plant extracts, plant components and the uses thereof
WO2009033103A1 (en) * 2007-09-07 2009-03-12 Bionovo, Inc. Estrogenic extracts of pueraria lobata willd, ohwi of the leguminosae family and uses thereof
KR100950564B1 (ko) * 2008-03-03 2010-04-01 동아대학교 산학협력단 한약재 추출물을 유효성분으로 함유하는 항암용 조성물

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of EP2762147A4 *
SO-JUNG, KIM ET AL.: "A Study on the Estrogenicity of Korean Arrowroot (Pueraria thunbergiana)", JOURNAL OF THE KOREAN SOCIETY OF FOOD SCIENCE AND NUTRITION, vol. 33, no. 1, 2004, pages 16 - 21, XP053026043 *

Also Published As

Publication number Publication date
KR20130032612A (ko) 2013-04-02
KR101357119B1 (ko) 2014-02-05
WO2013043011A2 (ko) 2013-03-28
EP2762147A2 (en) 2014-08-06
EP2762147A4 (en) 2014-08-06
US20140234451A1 (en) 2014-08-21
US9504724B2 (en) 2016-11-29
EP2762147B1 (en) 2015-11-18

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