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WO2012104080A8 - Accessible cooling system, especially for cryopreserving biological samples, and method for the operation thereof - Google Patents

Accessible cooling system, especially for cryopreserving biological samples, and method for the operation thereof Download PDF

Info

Publication number
WO2012104080A8
WO2012104080A8 PCT/EP2012/000451 EP2012000451W WO2012104080A8 WO 2012104080 A8 WO2012104080 A8 WO 2012104080A8 EP 2012000451 W EP2012000451 W EP 2012000451W WO 2012104080 A8 WO2012104080 A8 WO 2012104080A8
Authority
WO
WIPO (PCT)
Prior art keywords
cooling
cooling system
biological samples
liquid nitrogen
cooling chamber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2012/000451
Other languages
German (de)
French (fr)
Other versions
WO2012104080A3 (en
WO2012104080A2 (en
Inventor
Günter R. FUHR
Heiko Zimmermann
Bernd KRANZ
Tomm Schmidt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Helmholtz Zentrum Muenchen Deutsches Forschungszentrum fuer Gesundheit und Umwelt GmbH
Fraunhofer Gesellschaft zur Foerderung der Angewandten Forschung eV
Original Assignee
Helmholtz Zentrum Muenchen Deutsches Forschungszentrum fuer Gesundheit und Umwelt GmbH
Fraunhofer Gesellschaft zur Foerderung der Angewandten Forschung eV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helmholtz Zentrum Muenchen Deutsches Forschungszentrum fuer Gesundheit und Umwelt GmbH, Fraunhofer Gesellschaft zur Foerderung der Angewandten Forschung eV filed Critical Helmholtz Zentrum Muenchen Deutsches Forschungszentrum fuer Gesundheit und Umwelt GmbH
Priority to CN201280015818.XA priority Critical patent/CN103459949B/en
Priority to JP2013552134A priority patent/JP2014504716A/en
Priority to US13/983,342 priority patent/US20140000307A1/en
Priority to EP12702189.7A priority patent/EP2671034A2/en
Priority to CA2825234A priority patent/CA2825234C/en
Publication of WO2012104080A2 publication Critical patent/WO2012104080A2/en
Publication of WO2012104080A8 publication Critical patent/WO2012104080A8/en
Publication of WO2012104080A3 publication Critical patent/WO2012104080A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D3/00Devices using other cold materials; Devices using cold-storage bodies
    • F25D3/10Devices using other cold materials; Devices using cold-storage bodies using liquefied gases, e.g. liquid air
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/14Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/142Apparatus
    • A01N1/144Apparatus for temperature control, e.g. refrigerators or freeze-drying apparatus
    • A01N1/145Stationary or portable vessels generating cryogenic temperatures, e.g. liquid nitrogen baths
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D13/00Stationary devices, e.g. cold-rooms
    • F25D13/02Stationary devices, e.g. cold-rooms with several cooling compartments, e.g. refrigerated locker systems
    • F25D13/04Stationary devices, e.g. cold-rooms with several cooling compartments, e.g. refrigerated locker systems the compartments being at different temperatures
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D3/00Devices using other cold materials; Devices using cold-storage bodies
    • F25D3/10Devices using other cold materials; Devices using cold-storage bodies using liquefied gases, e.g. liquid air
    • F25D3/102Stationary cabinets
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D25/00Charging, supporting, and discharging the articles to be cooled
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D29/00Arrangement or mounting of control or safety devices
    • F25D29/001Arrangement or mounting of control or safety devices for cryogenic fluid systems

Landscapes

  • Engineering & Computer Science (AREA)
  • Thermal Sciences (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Combustion & Propulsion (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Devices That Are Associated With Refrigeration Equipment (AREA)
  • Refrigerator Housings (AREA)

Abstract

A cooling system (1), especially for cryopreserving biological samples (2), comprises a cooling chamber (100) delimited by a bottom area (110), side walls (120), and a top area (130), and a cooling device (200) for cooling the cooling chamber (100) using liquid nitrogen (220). The bottom area (110) is designed for direct cooling using the liquid nitrogen, and the cooling chamber (100) is dimensioned such that an operator (3) can access and move around in the cooling chamber (100). The bottom area (110) has a platform (111) which is permeable to vapor of the liquid nitrogen (220) and forms a support zone for the operator (3). Methods for operating the cooling system are also described.
PCT/EP2012/000451 2011-02-02 2012-02-01 Accessible cooling system, especially for cryopreserving biological samples, and method for the operation thereof Ceased WO2012104080A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CN201280015818.XA CN103459949B (en) 2011-02-02 2012-02-01 It is particularly useful for the cooling system being suitable for walking of low temperature storage biological specimen and the method for operating this kind of cooling system
JP2013552134A JP2014504716A (en) 2011-02-02 2012-02-01 Walkable cooling system mainly used for cryopreservation of biological samples and its operation method
US13/983,342 US20140000307A1 (en) 2011-02-02 2012-02-01 Accessible cooling system, especially for cryopreserving biological samples, and method for the operation thereof
EP12702189.7A EP2671034A2 (en) 2011-02-02 2012-02-01 Accessible cooling system, especially for cryopreserving biological samples, and method for the operation thereof
CA2825234A CA2825234C (en) 2011-02-02 2012-02-01 Accessible cooling system, especially for cryopreserving biological samples, and method for the operation thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102011010121.7 2011-02-02
DE102011010121.7A DE102011010121B4 (en) 2011-02-02 2011-02-02 Walk-in cooling system, in particular for the cryopreservation of biological samples, and method for their operation

Publications (3)

Publication Number Publication Date
WO2012104080A2 WO2012104080A2 (en) 2012-08-09
WO2012104080A8 true WO2012104080A8 (en) 2012-11-08
WO2012104080A3 WO2012104080A3 (en) 2013-01-24

Family

ID=45562275

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2012/000451 Ceased WO2012104080A2 (en) 2011-02-02 2012-02-01 Accessible cooling system, especially for cryopreserving biological samples, and method for the operation thereof

Country Status (7)

Country Link
US (1) US20140000307A1 (en)
EP (1) EP2671034A2 (en)
JP (1) JP2014504716A (en)
CN (1) CN103459949B (en)
CA (1) CA2825234C (en)
DE (1) DE102011010121B4 (en)
WO (1) WO2012104080A2 (en)

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CN105737471B (en) * 2016-02-04 2018-08-31 上海理工大学 Quickly cooling portable biometric sample Cord blood case
CA3193233C (en) * 2016-06-13 2025-11-18 Geoff ROWE System, method and apparatus for the regeneration of nitrogen energy within a closed loop cryogenic system
CN107054914A (en) * 2016-12-31 2017-08-18 重庆煌固包装制造有限公司 A kind of fresh-preserving container
CN106829202B (en) * 2017-01-13 2019-05-31 北京华晨世纪生物技术有限公司 Constant low temperature storage system and the method for removing Dewar fog
CN107691429A (en) * 2017-09-30 2018-02-16 曾里 A kind of gradient cooling mechanism and its method of work
CN107883629A (en) * 2017-12-12 2018-04-06 广州鲜之源生态冷链技术有限公司 The liquid nitrogen refrigerating apparatus and refrigerating method of a kind of rice
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US12196471B2 (en) 2019-10-30 2025-01-14 Liconic Ag High-efficiency low-temperature storage device
CN112097428A (en) * 2020-11-13 2020-12-18 金西盟(天津)人工智能有限责任公司 Biological sample liquid nitrogen tank refrigerator adopting triple refrigeration triple protection and heat insulation technology
CN113154740A (en) * 2021-05-21 2021-07-23 协和干细胞基因工程有限公司 Ultra-low temperature human genetic resource sample library
CN114739075B (en) * 2022-03-31 2023-06-16 青岛海尔生物医疗股份有限公司 Method and device for cooling program cooling instrument and program cooling instrument

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Also Published As

Publication number Publication date
WO2012104080A3 (en) 2013-01-24
CA2825234C (en) 2018-11-27
CN103459949A (en) 2013-12-18
US20140000307A1 (en) 2014-01-02
JP2014504716A (en) 2014-02-24
EP2671034A2 (en) 2013-12-11
CA2825234A1 (en) 2012-08-09
DE102011010121A1 (en) 2012-08-02
WO2012104080A2 (en) 2012-08-09
CN103459949B (en) 2016-06-01
DE102011010121B4 (en) 2016-09-01

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