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WO2012067544A2 - Moyen antidouleur individuel de type par inhalation - Google Patents

Moyen antidouleur individuel de type par inhalation Download PDF

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Publication number
WO2012067544A2
WO2012067544A2 PCT/RU2011/000886 RU2011000886W WO2012067544A2 WO 2012067544 A2 WO2012067544 A2 WO 2012067544A2 RU 2011000886 W RU2011000886 W RU 2011000886W WO 2012067544 A2 WO2012067544 A2 WO 2012067544A2
Authority
WO
WIPO (PCT)
Prior art keywords
individual
gas mixture
painkiller
gas
gas cylinder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/RU2011/000886
Other languages
English (en)
Russian (ru)
Other versions
WO2012067544A3 (fr
Inventor
Анатолий Анатольевич КУТЬЕВ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO2012067544A2 publication Critical patent/WO2012067544A2/fr
Publication of WO2012067544A3 publication Critical patent/WO2012067544A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/12—Preparation of respiratory gases or vapours by mixing different gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/20—Valves specially adapted to medical respiratory devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0208—Oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0266—Nitrogen (N)
    • A61M2202/0283—Nitrous oxide (N2O)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0291—Xenon

Definitions

  • the utility model relates to the field of medicine and can be used as a symptomatic therapeutic agent of the inhalation type in autoanalgesia.
  • An analgesic agent which is used as an auto-analgesic and is a pharmaceutical composition comprising an antispasmodic component and / or at least one non-narcotic analgesic, purine alkaloid, sedative component barbiturate and at least one compound selected from the group of non-specific anti-inflammatory drugs (NSAIDs).
  • NSAIDs non-specific anti-inflammatory drugs
  • a known method of limb electroanalgesia which can also be used for autoanalgesia, involves applying a pulsed electric current to nerve trunks, the active electrode being injected through the microirrigator using the puncture method, and the passive electrode is fixed on the skin (RU 2002125946, 2002).
  • electroanalgesia which can be used to relieve and suppress acute and chronic pain of a post-traumatic and neurological nature, in which modulated stimulating current pulses are used for electroanalgesia, and the pulses are modulated by a transformed patient's breathing signal (RU 2019205, 1994).
  • a common disadvantage of the above methods is their inability to improve and normalize metabolic processes. Due to its multicomponentity, an analgesic in the form of a pharmaceutical composition can cause allergies, exacerbation of peptic ulcer, gastric bleeding, gastritis, and a sedative component, barbiturate, leads to inhibition of consciousness, drowsiness. Electroanalgesia methods require a special electric device, knowledge of the technique of applying electrodes, sterility for introducing a microirrigator using the puncture method, and searching for optimal current parameters. The period of adaptation to electrical influences and waiting the analgesic effect is more than 20 minutes, and the analgesic effect is absent in more than 20% of patients.
  • nitrous oxide is used in a mixture with oxygen using special devices for gas anesthesia. Usually they start with the use of a mixture containing 70-80% nitrous oxide and 30-20% oxygen, then the amount of oxygen is increased to 40-50%.
  • special anesthetic devices with a mixture of nitrous oxide (40-75%) and oxygen.
  • the woman in labor begins to inhale the mixture when the precursors of the contractions appear and ends the inhalation at the height of the contractions or towards the end of the contractions.
  • an individual analgesic agent made in the form of a gas cylinder, is designed to prepare several user-friendly analgesic portions of a gas mixture containing oxygen and nitrous oxide and / or xenon, with an oxygen content of at least 10 vol.%.
  • the patented product is convenient to use, safe to use, accessible for use by elderly people, since the volume of the cylinder, its size and weight are not large and are designed for prompt individual use, while the structurally gas cylinder is reliable and easy to operate, does not require special skills and auxiliary devices.
  • Another feature of the utility model is that the state parameters of the gas mixture used, namely the gas pressure and its volume, exclude the possibility of injury in the process of individual use of the gas mixture, which has analgesic properties.
  • the weight parameters of the gas cylinder due to the parameters and properties of the gas mixture, are so small that they are convenient for use by both adults and elderly people, which cannot be said about gas stationary cylinders for industrial use, the weight of which sometimes reaches 50 kg, and gas pressure ⁇ 100-150 atm.
  • an individual inhalation-type painkiller contains a gas cylinder with a volume of not more than 4.39 liters under a pressure of not more than 45 atmospheres containing oxygen and nitrous oxide and / or xenon, and the gas cylinder is equipped with a controllable exhaust valve with the ability to batch supply of the gas mixture to the user with an oxygen content of not less than 20 vol.%.
  • a controlled outlet valve would be in communication with a mask supplying the gas mixture to the nasal or nasal cavity.
  • the face mask would be configured to take air from the atmosphere and supply it to the inhaled gas mixture and could be equipped with a check valve or valves.
  • an intermediate storage tank for the gas mixture could be included in the system, for example: an air bag.
  • composition of the gas mixture would additionally contain nitrogen or argon or helium or carbon dioxide.
  • Figure 1 shows a schematic utility model.
  • Figure 2 is a utility model made using a facial mask.
  • Fig.Z is a utility model having an elastic bag.
  • an individual inhalation-type painkiller contains a gas cylinder 1 with an internal volume of not more than 4.39 liters, in which there is a painkiller with a mixture of gases with a volume of not more than 450 liters under a pressure of not more than 45 atmospheres.
  • the upper limit of the volume of the gas cylinder equal to 4.39 liters, is due to safety conditions for individual use in everyday life and similar conditions, as well as economic feasibility and was obtained empirically.
  • the analgesic gas mixture 2 consists of a mixture of gases: oxygen and nitrous oxide and / or xenon, with an oxygen content of not less than 10% of the total volume. It is advisable to implement the means with a gas cylinder 1 containing a gas mixture with Xe: 0 2 or LiGO, with a capacity of 500 to 1500 cm 3 , it is possible to use gas cylinders 1 of small capacity, so-called single action, for 5-12 breaths, i.e. volume up to 50 cm 3 .
  • an individual painkiller is a 1 liter cylinder made of 0.4 mm thick aluminum and filled with a gas mixture of 20 liters of gas, while the gas cylinder weighs only 170 grams and the volume of the gas mixture is sufficient to provide inhalation anesthesia in for 10 minutes.
  • an individual painkiller is a 1.5-liter bottle made of durable material, for example, titanium alloys with a thickness of 0.23 mm, withstanding a pressure of 45 atmospheres, filled with a gas mixture, weighs only 3 kg. 400 gr.
  • the amount of liquefied gases is only 1 .5 liters, which corresponds to 450 liters of the gaseous phase. This amount of gas mixture is intended for inhalation analgesia for 225 minutes.
  • the use of cylinders with the specified ratio of pressure and volume is allowed without special training and permission
  • the weight parameters of an individual painkiller make it indispensable for people who have various ailments that cause pain processes in the body and require prompt action to suppress pain.
  • the gas cylinder 1 is equipped with a controllable exhaust valve 3 with the possibility of portioned supply of the gas mixture 2 to the user with an oxygen content of not less than 20 vol.%.
  • the controlled exhaust valve 3 is communicated by means of connecting means 4 (pipe, piping, etc.) with a tip 5 for gripping with lips (teeth), which is convenient for supplying the gas mixture 2 to the oral user cavity during inhalation.
  • the tip 5 is configured to take air from the atmosphere through line 6 and supply it to the inhaled gas mixture.
  • the highway 6 is equipped with a crane 7.
  • the controlled exhaust valve 3 is in communication with the face mask 8, which ensures the supply of the gas mixture to the nasal or nasal cavity (not shown in the drawings).
  • the face mask 8 is configured to take air from the atmosphere through the pipe 10 (figure 2) and supply it to the inhaled gas mixture.
  • the pipe 10 is equipped with a valve 1 1 or a check valve (not shown in the drawings) that lets air in when it is inhaled.
  • an intermediate storage tank 12 for inhaled gas mixture is introduced into the system, for example: a bag made of elastic material and controlled by control valves 13 and 14 the amount supplied from outside the air and the inhaled gas mixture.
  • the storage tank 12 can be pre-filled with air, and then the process is similar to that described above, the gas is supplied to the tank 12, mixed with air, the amount of oxygen in the gas mixture increases, performing an analgesic effect that is soft in time.
  • the essence of the utility model is to achieve a technical result in the method of autoanalgesia, in which the user, while conscious, spends the xenon-oxygen mixture or a mixture of nitrous oxide with oxygen independently (without the participation of medical workers), while achieving a therapeutic effect and relief of pain. Thanks to the properties of the gas mixtures used, almost instant relief of spasms, anesthesia, relief of pain shock, relief from heart attacks, including heart attacks, is provided. The peculiarity of the use of the device lies in the possibility of its use without the participation of a doctor, in particular an anesthesiologist, since a small amount of this gaseous medium cannot cause irreversible consequences or harm human health, and the presence of oxygen in the mixture eliminates the occurrence of hypoxia.
  • the effect of anesthesia occurs after one, two breaths, i.e. it has a fast-acting property.
  • the mixture additionally contains nitrogen or argon or helium or carbon dioxide.
  • the user if necessary (toothache, headache, heart attack with a pain effect, etc.), inserts the tip 5 into the mouth, closes the nose, pulsates the exhaust valve 3, the pulse duration determines the volume of a portion of the gas mixture 2, and takes a breath and exhale. In some cases, breath holding is possible. In this case, the gas mixture 2 from the cylinder 1 through the exhaust valve 3 enters the body of the user.
  • the user provides control of the supply volume, as well as the feed rate of the gas mixture 2.
  • the gas mixture 2 exits the cylinder and completely enters the user's body, when the user exhales or holds his breath, the valve closes and the gas mixture from the gas cylinder does not go, which ensures a rational consumption of the contents of the container.
  • the patient is a man of 40 years. Almost every day after work, makes a long journey from work home for 1, 5-2 hours, and sometimes more. After driving a car for a long time, being in traffic congestion, and in the summer in a polluted air, often experiences a headache of an antispasmodic nature, this is often caused by "poisoning" by exhaust gases. To date, he often used strong drugs - Pentalgin and the like, but the effect did not come right away, and the consequences of these drugs leave much to be desired. In the last such case, I tried the device according to the utility model “Individual anesthetic of an inhalation type”, made in accordance with FIG. one .
  • Example N ° 3. The patient is an elderly person of 74 years, like many people of this age, he sometimes has in unforeseen cases heart attacks with pain. So, while walking in the park, he squeezed his chest and suffered acute pain, he used the device “Individual anesthetic of an inhalation type” made in accordance with FIG. The user put on the face mask, opened the valve 3, while the gas mixture from the cylinder 1 is mixed with air coming from the outside into the mask in communication with the atmosphere and in this diluted form enters the lungs of the person, i.e. the user receives a painkiller gas mixture in diluted form directly into the lungs and then into the circulatory system. After the user began to breathe this mixture, heart pain became less intense, and after 5 minutes the pain in the heart disappeared completely.
  • the gas mixture cylinder is safe to operate, like any household aerosol cans, for example, for air disinfection, etc., has small dimensions and weight - about 300 grams

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Le modèle d'utilité concerne le domaine de la médecine et peut s'utiliser en tant que moyen thérapeutique symptomatique lors de l'auto-analgésie de type par inhalation. Le but visé par la présente invention consiste à créer un moyen antidouleur individuel qui possède des caractéristiques techniques élargies permettant son utilisation à domicile ou dans de petits établissements de soins ainsi que lors des randonnées et dans des transports, par exemple, en vol ou dans une ambulance, car ce moyen ne nécessite ni mode d'emploi ni dispositifs auxiliaires spéciaux. Pour réaliser ce but, le moyen antidouleur individuel de type par inhalation comprend une bonbonne de gaz possédant un volume de 4,39 litre au maximum à une pression de 45 atmosphères au maximum qui contient de l'oxygène et du monoxyde d'azote et/ou du xénon, la bonbonne de gaz étant équipée d'une soupape d'évacuation commandée permettant l'admission dosée d'un mélange gazeux dans les poumons de l'utilisateur avec une teneur en oxygène d'au moins 20 % en volume.
PCT/RU2011/000886 2010-11-15 2011-11-11 Moyen antidouleur individuel de type par inhalation Ceased WO2012067544A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2010146307 2010-11-15
RU2010146307 2010-11-15

Publications (2)

Publication Number Publication Date
WO2012067544A2 true WO2012067544A2 (fr) 2012-05-24
WO2012067544A3 WO2012067544A3 (fr) 2012-08-09

Family

ID=46084562

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/RU2011/000886 Ceased WO2012067544A2 (fr) 2010-11-15 2011-11-11 Moyen antidouleur individuel de type par inhalation

Country Status (2)

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UA (1) UA72025U (fr)
WO (1) WO2012067544A2 (fr)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3012694A (en) * 1958-10-22 1961-12-12 Johnston William Derrick Gas dispensing device
RU2080884C1 (ru) * 1994-09-30 1997-06-10 Акционерное общество "Радар ММС" Холдинговой компании "Ленинец" Аппарат ингаляционного наркоза
RU2291718C2 (ru) * 2002-08-20 2007-01-20 Закрытое акционерное общество "Специальное конструкторское бюро экспериментального оборудования при Государственном научном центре Российской Федерации "Институт медико-биологических проблем" Российской Академии наук (ЗАО "СКБ ЭО при ГНЦ РФ "ИМБП" РАН") Способ регуляции физиологического состояния биологического объекта смесями газов
RU2271815C2 (ru) * 2003-11-21 2006-03-20 Николай Евгеньевич Буров Способ аутоанальгезии ксенон-кислородной смесью

Also Published As

Publication number Publication date
WO2012067544A3 (fr) 2012-08-09
UA72025U (ru) 2012-08-10

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