[go: up one dir, main page]

WO2011011738A3 - Eclairage pour instruments de biotechnologie - Google Patents

Eclairage pour instruments de biotechnologie Download PDF

Info

Publication number
WO2011011738A3
WO2011011738A3 PCT/US2010/043131 US2010043131W WO2011011738A3 WO 2011011738 A3 WO2011011738 A3 WO 2011011738A3 US 2010043131 W US2010043131 W US 2010043131W WO 2011011738 A3 WO2011011738 A3 WO 2011011738A3
Authority
WO
WIPO (PCT)
Prior art keywords
biological sample
reaction region
target
temperature
illumination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2010/043131
Other languages
English (en)
Other versions
WO2011011738A2 (fr
Inventor
Liana Ilkova
Casey Mcfarland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Life Technologies Corp
Original Assignee
Life Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Technologies Corp filed Critical Life Technologies Corp
Publication of WO2011011738A2 publication Critical patent/WO2011011738A2/fr
Publication of WO2011011738A3 publication Critical patent/WO2011011738A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/251—Colorimeters; Construction thereof
    • G01N21/253—Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0822—Slides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B01L2300/0838—Capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5088—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above confining liquids at a location by surface tension, e.g. virtual wells on plates, wires
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

L'invention concerne un système pouvant présenter au moins une région de réaction comprenant un échantillon biologique ; un mécanisme de régulation de la température configuré pour réguler la température de la ou des régions de réaction ; une lampe sans électrode configurée pour éclairer la ou les régions de réaction ; et un détecteur configuré pour détecter au moins un signal provenant de la ou les régions de réaction. L'invention concerne également un procédé de détection d'au moins une cible dans un échantillon biologique qui peut consister à réguler la température d'un échantillon biologique comprenant au moins une cible ; à exciter au moins un marqueur pour produire un signal d'émission, l'excitation consistant à éclairer l'échantillon biologique avec de la lumière provenant d'une lampe sans électrode ; et à détecter le signal d'émission.
PCT/US2010/043131 2009-07-24 2010-07-23 Eclairage pour instruments de biotechnologie Ceased WO2011011738A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22843609P 2009-07-24 2009-07-24
US61/228,439 2009-07-24

Publications (2)

Publication Number Publication Date
WO2011011738A2 WO2011011738A2 (fr) 2011-01-27
WO2011011738A3 true WO2011011738A3 (fr) 2011-06-30

Family

ID=43592020

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/043131 Ceased WO2011011738A2 (fr) 2009-07-24 2010-07-23 Eclairage pour instruments de biotechnologie

Country Status (1)

Country Link
WO (1) WO2011011738A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9146248B2 (en) 2013-03-14 2015-09-29 Intelligent Bio-Systems, Inc. Apparatus and methods for purging flow cells in nucleic acid sequencing instruments
US9591268B2 (en) 2013-03-15 2017-03-07 Qiagen Waltham, Inc. Flow cell alignment methods and systems
KR102081228B1 (ko) * 2017-03-06 2020-02-26 한림대학교 산학협력단 중합 효소 연쇄 반응 제어 방법 및 시스템

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030143575A1 (en) * 2000-03-07 2003-07-31 Caria Mario Raimondo Method and system for the simultaneous and multiple detection and quantification of the hybridization of molecular compounds such as nucleic acids, dna rna, pna, and proteins
US20050064583A1 (en) * 2003-09-24 2005-03-24 Frank Caruso Temperature controlled illuminator for treating biological samples
WO2005068976A2 (fr) * 2004-01-14 2005-07-28 Applera Corporation Detecteur a indicateurs fluorescents a changement automatique des filtres
US20090167201A1 (en) * 2007-11-07 2009-07-02 Luxim Corporation. Light source and methods for microscopy and endoscopy

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030143575A1 (en) * 2000-03-07 2003-07-31 Caria Mario Raimondo Method and system for the simultaneous and multiple detection and quantification of the hybridization of molecular compounds such as nucleic acids, dna rna, pna, and proteins
US20050064583A1 (en) * 2003-09-24 2005-03-24 Frank Caruso Temperature controlled illuminator for treating biological samples
WO2005068976A2 (fr) * 2004-01-14 2005-07-28 Applera Corporation Detecteur a indicateurs fluorescents a changement automatique des filtres
US20090167201A1 (en) * 2007-11-07 2009-07-02 Luxim Corporation. Light source and methods for microscopy and endoscopy

Also Published As

Publication number Publication date
WO2011011738A2 (fr) 2011-01-27

Similar Documents

Publication Publication Date Title
WO2009090511A3 (fr) Procédé et appareil de contrôle d'intensité lumineuse
EP2177897A3 (fr) Appareil de détection optique pour biopuce
PL2136129T3 (pl) Lampa operacyjna z regulacją jasności zależną od odległości
EP3501384A3 (fr) Procédé pour imagerie et surveillance par fluorescence
EP2062510A3 (fr) Vitrine
MX2012000052A (es) Metodo de deteccion de resonancia de plasmon superficial y sistema de deteccion.
TW200719672A (en) Electronic device capable of operating a function according to detection of environmental light
WO2005074506A3 (fr) Fluorimetre a cellule ouverte-extremite interchangeable
WO2013049702A3 (fr) Systèmes et procédés pour une analyse biologique
WO2007137060A3 (fr) Systèmes, procédés, et appareil destinés au séquençage d'une molécule unique
TW200723966A (en) Illumination brightness and color control system and method thereof
WO2006062895A3 (fr) Systeme et procede pour l'imagerie et la mesure optique in vivo
WO2008066747A3 (fr) Dispositif de détection de la fluorescence à base d'électroluminescence
WO2009010926A3 (fr) Procédé de traitement de lumière dans une structure et système d'éclairage
WO2007087315A3 (fr) Procédé et système de détection combinée raman + libs
WO2010129800A3 (fr) Système et procédé d'analyse de couleur
WO2009075306A1 (fr) Procédé de mesure de la luminescence et système de mesure de la luminescence
BR112012010101A2 (pt) elemento de segurança e método para autenticar ou identicar um objeto
WO2012063149A3 (fr) Procédés de détection désagrégée de lumière artificielle et de lumière du jour
ES2638294T3 (es) Método de detección de cáncer
MX350372B (es) Metodo para posicionar un miembro de formacion de luz.
WO2008044195A3 (fr) Système et procédé de régulation de la lumière
MX2014012772A (es) Analizador de muestras de ensayo biologico.
WO2009118570A3 (fr) Procédé de détection
WO2011011738A3 (fr) Eclairage pour instruments de biotechnologie

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 10802991

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 10802991

Country of ref document: EP

Kind code of ref document: A2