[go: up one dir, main page]

WO2011060691A1 - Composition insecticide contenant du cyantraniliprole et du benzoate d'emamectine - Google Patents

Composition insecticide contenant du cyantraniliprole et du benzoate d'emamectine Download PDF

Info

Publication number
WO2011060691A1
WO2011060691A1 PCT/CN2010/078514 CN2010078514W WO2011060691A1 WO 2011060691 A1 WO2011060691 A1 WO 2011060691A1 CN 2010078514 W CN2010078514 W CN 2010078514W WO 2011060691 A1 WO2011060691 A1 WO 2011060691A1
Authority
WO
WIPO (PCT)
Prior art keywords
composition
cyanamide
weight
polyoxyethylene ether
amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2010/078514
Other languages
English (en)
Chinese (zh)
Inventor
欧晓明
裴晖
余淑英
马俊凯
喻快
林雪梅
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hunan Research Institute of Chemical Industry
Original Assignee
Hunan Research Institute of Chemical Industry
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hunan Research Institute of Chemical Industry filed Critical Hunan Research Institute of Chemical Industry
Publication of WO2011060691A1 publication Critical patent/WO2011060691A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles

Definitions

  • the invention relates to an insecticidal composition of cyanamide and emamectin benzoate and a preparation method thereof.
  • Cyantrani l iprole trade name cyazypyrTM, experimental code DPX-HGW86, chemical name 3-bromo-N-(4-cyano-2-methyl-6-(methylaminocarbonyl)benzene -1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide, a novel orthoylaminobenzamide insecticide developed by DuPont of the United States, its chemistry The structure is as follows:
  • Cyantraniliprole cyanamide is a insect-inhibitor of insect fish, which mainly exhibits contact and stomach toxicity by inducing the release of intracellular calcium ions regulated by insect fish, which can be used for rice, vegetables, cotton, sugar beet, etc.
  • the control of crop pests, especially for the control of various lepidopteran pests, has a special effect better than other commercial insecticides used in current production, and there is no cross-resistance to other insecticides. .
  • cyanamide is internationally recognized as a new generation of highly effective insecticides.
  • the drug is not ideal for the control of non-Lepidoptera pests such as planthoppers, spider mites and various mites. Since the compound is still under the patent protection period, China is still unable to produce the original drug.
  • Emamectin benzoate (“Avi”) is a structure in which the soil release line Streptomyces avermi tilis MA-4680 fermentation product avermectin B1 is used as the parent compound by Wilkinson reaction. a novel highly efficient semi-synthetic macrolide antibacterial antibiotic
  • the most sensitive target site in insects is the stimulation of neurotransmitters such as glutamine and GABA-inhibiting chloride channels, which cause cell loss and muscle paralysis through a specialized high-affinity binding site, disrupting nerve conduction. When the insects contact or feed, they stop eating immediately, causing irreversible paralysis and death. It is characterized by low toxicity, high efficiency, high selectivity and good compatibility with the environment.
  • Awei salt has been used in agricultural production for many years. However, according to the Key Laboratory of Crop Disease and Insect Resistance Monitoring and the FA0 Resistance Action Committee of the Agricultural Department of Nanjing Agricultural University, the single use of Awei salt has been used in some areas for vegetable pests. Plutella xylostella and the like produce resistance problems. Therefore, the compounding of the methicillin and cyanamide showed that the compounded insecticidal composition can achieve the purpose of expanding the spectrum of prevention, improving the efficacy, reducing the risk of pest resistance and reducing the cost of agriculture.
  • An object of the present invention is to provide an insecticidal composition of cyanamide and emamectin benzoate (referred to as "a vitamin salt") and a preparation method thereof.
  • the invention adopts modern bioassay technology and according to the co-toxicity coefficient method of Sun YP & Johnson ER (1960), screens out cyanamide and carbaryl salt as effective insecticidal active ingredients, and constitutes a pesticidal composition with obvious synergistic effect. 2 ⁇ 50 ⁇ ( ⁇ ) The total amount of the insecticidal composition is 2. 2 ⁇ 50% (% by weight) .
  • the insecticidal composition of cyanamide and emamectin benzoate by adding a solvent or an emulsifier, a wetting and dispersing agent, a stabilizer, an antifreezing agent, an antifoaming agent, and thickening Agents, binders, disintegrants, fillers, processed into emulsifiable concentrates (EC), aqueous emulsions (EW), microemulsions (ME), suspending agents (SC), wettable powders according to processing methods known to those skilled in the art ( WP) or water-dispersible granules (WDG).
  • EC emulsifiable concentrates
  • EW aqueous emulsions
  • ME microemulsions
  • SC suspending agents
  • WP wettable powders according to processing methods known to those skilled in the art
  • WDG water-dispersible granules
  • the solvent of the present invention is one or more of benzene, xylene, toluene, cyclohexanone, methanol, ethylene glycol, isobutanol, ethyl acetate, dimethylformamide, water, deionized water. a mixture, the amount of which is based on the total weight of the composition
  • the emulsifier of the present invention is biphenol polyoxyethylene ether, polyoxyethylene polyoxypropylene oxime copolymer, methylbenzyl phenol ethoxylate, fatty alcohol polyoxyethylene ether, phenethyl phenol polyoxygen Ethylene polyoxypropylene ether, dibenzyl biphenol polyoxyethylene ether, castor oil polyoxyethylene polyoxypropylene ether, sorbitan fatty acid polyoxyethylene ether, alkylbenzene sulfonate, dodecylbenzenesulfonic acid Sodium, lignosulfonate, agricultural milk 500, agricultural milk 1601, agricultural milk 0203B, agricultural milk 0201B,
  • the wetting and dispersing agent of the present invention is a mono-fatty acid sulfate salt, an alkylbenzene sulfonate, a lignosulfonate, an alkylnaphthalenesulfonate formaldehyde condensate, sodium dibutylnaphthalenesulfonate, an alkyl group.
  • Phenolic polyoxyethylene ether fatty alcohol polyoxyethylene ether, phenethyl phenol polyoxyethylene ether, alkyl aryl polyoxyethylene ether, dodecyl polyoxyethylene ether phosphate, lauryl sulfate, wet penetration
  • One or more of the agents JFC and sodium carboxymethylcellulose are used in an amount of from 1 to 30% by weight based on the total weight of the composition.
  • the stabilizer of the present invention is one or more of aminobenzoic acid, pyrogallic acid, castor oil, epoxidized soybean oil, urea, tolyl glycidol, and the amount thereof is 0. 1 to 5% (by weight).
  • the antifreeze agent of the present invention is a mixture of one or more of ethylene glycol, polyethylene glycol, glycerin, propylene glycol, epichlorohydrin, urea, glycerol, sorbitol, and the total amount is the total weight of the composition. 1 to 8% (by weight).
  • the antifoaming agent of the present invention is a mixture of one or more of silicone oil, silicone silicone and epoxidized soybean oil, and is usually used in an amount of 10 to 30% by weight based on the total weight of the composition.
  • the binder of the present invention is one or more of starch, cyclodextrin, and polyvinyl alcohol in an amount of from 1 to 10% by weight based on the total weight of the composition.
  • the disintegrating agent of the present invention is one or more of bentonite, ammonium sulfate, and urea in an amount of 5 to 15% by weight based on the total weight of the composition.
  • the filler of the present invention is one or more of kaolin, bentonite, silica, diatomaceous earth, activated clay, and talc, and is used in an amount of 15 to 75% by weight based on the total weight of the composition.
  • the active ingredient of the invention When used in an amount of 1 to 4 g/mu, it can be uniformly sprayed on rice, vegetables, tea trees and the like by spraying or dusting, and can effectively control rice leaf roller, rice stem borer, and stem borer. , flying locust or spider mites, beet armyworm, diamondback moth, cabbage caterpillar, tea mites, tea moths and so on.
  • the co-toxicity coefficient of cyanamide and acetophene salt is obviously greater than 100, and the dosage of the mixture in the field is 1 ⁇ 2g, and the cyanamide and the carbaryl salt are used separately to achieve the same control effect of the mixture.
  • the amount of acres used is 2 to 3 grams and
  • composition of the invention has obvious synergistic effect on controlling pests, improves the drug effect, reduces the dosage of the active ingredients of the pesticide, and reduces the agricultural cost.
  • the invention realizes the insecticidal spectrum of two different insecticidal spectrums, greatly improves the insecticidal spectrum, and has special effects not only for the control of various lepidopteran pests, but also for other insect pests such as planthoppers and spider mites. And the control effect of various mites They are all ideal.
  • the invention has different action mechanisms for the two effective insecticidal components, and achieves complementary advantages, which not only effectively delays the generation of pest resistance, but also facilitates the comprehensive management of pests, can replace high-toxic pesticide varieties, and is effective. Reduce pollution to the environment and improve the quality and safety of agricultural products.
  • cyanamide 41 ⁇ 2 gamma salt lg, sodium dodecyl benzene sulfonate 5g, lignosulfonate 5g, lauryl alcohol
  • Polyoxyethylene ether 6g acrylic acid homopolymer sodium salt 4g, polyethylene glycol 2g, cyclodextrin lg, polyvinyl alcohol lg, bentonite lg, white carbon black 5, kaolin 25g.
  • the components were mixed and subjected to ultrafine pulverization, granulated, dried, and sieved to obtain 45% water-dispersible granules.
  • Example 14 Determination of virulence of cyanamide, avidin and different ratios against armyworm
  • the test agent is formulated into a certain concentration of the mother liquor by the method of immersion leaf worm, and then diluted to 5 concentrations with water to be used, and the water is set as a control.
  • the fresh corn leaves are cut into pieces of about 50 mm in length, and the cut leaves are immersed in the prepared test solution for 10 seconds, taken out and allowed to dry naturally, and then placed in a filter paper in advance. Petri dish ( ⁇ 90 ⁇ ). Then, the 3rd instar larvae of the armyworm were inserted into the dish, 10 dishes per dish, and repeated 3 times per concentration. After the treatment is completed, the lid is placed, placed in the recovery chamber, and observed regularly.
  • the death is recorded after 48 hr, the mortality rate is calculated (%), and the virulence regression equation and correlation coefficient (r) are obtained according to the probability value analysis method. And lethal concentration (LC 5 .).
  • the joint action approach uses the co-toxicity coefficient (CTC) method proposed by Sun YP & Johnson ER (1960). Generally, when the co-toxicity coefficient is significantly greater than 120, it means synergistic effect. When the co-toxicity coefficient is 80-120, it means that it has an additive effect, and when the co-toxicity coefficient is obviously less than 80, it means antagonism.
  • the formula for calculating the co-toxicity coefficient is as follows: Standard drug LC ⁇ or ⁇ >.
  • Theoretical virulence index ( ⁇ 77) ⁇ 77 of the drug ⁇ % of ⁇ in the mixture + ⁇ 77 of the agent ⁇ ⁇ % of ⁇ in the mixture ⁇ Mixed Measured virulence index (ATI)
  • a vitamin salt (EB) ⁇ 5. 0911+1. 9909 ⁇ 0. 9687 0. 90
  • the virulence of cyanamide, avidin and different ratios against C. serrata was determined by plant dipping method. The results are shown in Table 2. As can be seen from Table 2, the ratio of cyanamide to carbaryl salt is 0.1:1, 0.5:1, 1:1, 10:1, 20:1, 40:1 and 80:1, 99:1. The virulence of the beet armyworm was significantly enhanced by compounding. The co-toxicity coefficient was 149. 68, 173. 46, 137. 60, 196. 34, 225. 49, 247. 79, 200 14 and 134. 21.
  • Example 16 Field efficacy test of compounding cyanamide and methyl salt to control Plutella xylostella
  • Example 17 Field efficacy test of compounding cyanamide and methyl salt to control rice leaf roller
  • Example 4 Product 2 78. 91B 92. 93B
  • Example 8 Product 2 79. 37B 92. 47B
  • Example 10 Product 2 80. 43B 95. 78B
  • Example 12 Product 2 82. 17B 96. 33AB

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

L'invention porte sur une composition insecticide comprenant du cyantraniliprole et du benzoate d'emamectine comme principes actifs en un rapport pondéral de 0,1 à 99:1, la teneur du cyantraniliprole et du benzoate d'emamectine étant de 2,2 à 50 % en poids. La composition peut être mise sous forme d'un concentré émulsionnable, d'une émulsion aqueuse, d'une microémulsion, d'une suspension, d'une poudre mouillable ou de granulés dispersibles dans l'eau par ajout d'un solvant, d'un émulsifiant, d'un dispersant mouillant, d'un stabilisant, d'un agent antigel, d'un agent antimousse, d'un agent épaississant, d'un adhésif, d'un délitant ou d'une charge. La composition peut être utilisée pour lutter efficacement contre des animaux nuisibles en particulier les animaux nuisibles pour le riz non décortiqué et les légumes.
PCT/CN2010/078514 2009-11-19 2010-11-08 Composition insecticide contenant du cyantraniliprole et du benzoate d'emamectine Ceased WO2011060691A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN200910044775.8 2009-11-19
CN 200910044775 CN101703054B (zh) 2009-11-19 2009-11-19 氰虫酰胺与甲胺基阿维菌素苯甲酸盐的杀虫组合物

Publications (1)

Publication Number Publication Date
WO2011060691A1 true WO2011060691A1 (fr) 2011-05-26

Family

ID=42373370

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2010/078514 Ceased WO2011060691A1 (fr) 2009-11-19 2010-11-08 Composition insecticide contenant du cyantraniliprole et du benzoate d'emamectine

Country Status (2)

Country Link
CN (1) CN101703054B (fr)
WO (1) WO2011060691A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103283734A (zh) * 2012-02-23 2013-09-11 陕西韦尔奇作物保护有限公司 一种含溴氰虫酰胺和生物源类的杀虫组合物

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101703054B (zh) * 2009-11-19 2012-10-10 湖南化工研究院 氰虫酰胺与甲胺基阿维菌素苯甲酸盐的杀虫组合物
CN102326577A (zh) * 2011-10-19 2012-01-25 北京燕化永乐农药有限公司 杀虫组合物
CN102405931B (zh) * 2011-11-20 2013-08-14 广东中迅农科股份有限公司 含有氰虫酰胺和辛硫磷的具有协同增效作用的农药组合物
CN103283744A (zh) * 2012-03-01 2013-09-11 陕西韦尔奇作物保护有限公司 一种含溴氰虫酰胺的杀虫组合物
CN102626085A (zh) * 2012-03-29 2012-08-08 广西田园生化股份有限公司 含氰虫酰胺与大环内酯类杀虫剂的超低容量液剂
CN103518733B (zh) * 2013-10-24 2015-09-16 江苏龙灯化学有限公司 一种含乙基多杀菌素和溴氰虫酰胺的杀虫组合物
CN104186504A (zh) * 2014-09-25 2014-12-10 江苏省绿盾植保农药实验有限公司 一种含有甲维盐和溴氰虫酰胺的杀虫组合物及其应用
CN104304281A (zh) * 2014-09-29 2015-01-28 江苏省绿盾植保农药实验有限公司 一种含有甲维盐的复合杀虫剂及其应用

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006007595A2 (fr) * 2004-07-01 2006-01-19 E.I. Dupont De Nemours And Company Melanges synergiques d'agents de lutte contre les invertebres a base d'anthranilamide
CN1889837A (zh) * 2003-12-04 2007-01-03 拜尔农作物科学股份公司 包含邻氨基苯甲酰胺及至少一种其它杀昆虫剂的杀昆虫活性物质结合物
CN1988803A (zh) * 2004-07-26 2007-06-27 杜邦公司 邻氨基苯甲酰胺无脊椎害虫防治剂混合物
CN101188934A (zh) * 2005-06-03 2008-05-28 巴斯福股份公司 杀虫混合物
CN101703054A (zh) * 2009-11-19 2010-05-12 湖南化工研究院 氰虫酰胺与甲胺基阿维菌素苯甲酸盐的杀虫组合物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1599463E (pt) * 2003-01-28 2013-09-03 Du Pont Insecticidas à base de ciano-antranilamida

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1889837A (zh) * 2003-12-04 2007-01-03 拜尔农作物科学股份公司 包含邻氨基苯甲酰胺及至少一种其它杀昆虫剂的杀昆虫活性物质结合物
WO2006007595A2 (fr) * 2004-07-01 2006-01-19 E.I. Dupont De Nemours And Company Melanges synergiques d'agents de lutte contre les invertebres a base d'anthranilamide
CN1988803A (zh) * 2004-07-26 2007-06-27 杜邦公司 邻氨基苯甲酰胺无脊椎害虫防治剂混合物
CN101188934A (zh) * 2005-06-03 2008-05-28 巴斯福股份公司 杀虫混合物
CN101703054A (zh) * 2009-11-19 2010-05-12 湖南化工研究院 氰虫酰胺与甲胺基阿维菌素苯甲酸盐的杀虫组合物

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103283734A (zh) * 2012-02-23 2013-09-11 陕西韦尔奇作物保护有限公司 一种含溴氰虫酰胺和生物源类的杀虫组合物

Also Published As

Publication number Publication date
CN101703054A (zh) 2010-05-12
CN101703054B (zh) 2012-10-10

Similar Documents

Publication Publication Date Title
WO2011060691A1 (fr) Composition insecticide contenant du cyantraniliprole et du benzoate d'emamectine
CN107743976B (zh) 杀虫杀螨组合物
CN101703051B (zh) 含氰虫酰胺和杀虫单的杀虫组合物及其用途
CN100586282C (zh) 含氯虫酰胺和杀虫单的杀虫组合物
CN101185440B (zh) 一种含有阿维菌素的复配杀虫剂
UA124166C2 (uk) Поліморфи
CN103300019B (zh) 一种杀虫组合物
CN102388892B (zh) 含氯虫酰胺与杀虫环的杀虫组合物
CN101406195B (zh) 含有乙虫腈和阿维菌素具有增效杀虫作用的组合物
CN103404530B (zh) 一种杀虫组合物及其应用、制剂
CN115251064A (zh) 一种杀菌杀虫组合物及其应用
CN103314988A (zh) 一种含啶虫丙醚与拟除虫菊酯类的杀虫组合物
CN112237194B (zh) 一种含环溴虫酰胺的杀虫组合物
CN116784336A (zh) 一种含双酰胺类杀虫剂的组合物及其应用
CN103518773B (zh) 具有增效作用的杀虫组合物
CN109845740B (zh) 一种含氟氯虫双酰胺与双酰肼类杀虫剂的杀虫组合物
CN112655713A (zh) 含有硫虫酰胺和氟啶虫酰胺的农业杀虫组合物及其用途
WO2018032889A1 (fr) Composition insecticide ayant un effet synergique
CN116138263B (zh) 含有天维菌素b和乙螨唑的杀螨组合物
CN115886024B (zh) 含4-苯氧基-2,6-二异丙基苯硫代异氰酸酯和四唑虫酰胺的杀虫组合物及应用
CN112544627A (zh) 一种杀虫组合物在防治黄瓜黄胸蓟马、月季西花蓟马或芒果茶黄蓟马中的用途
CN104082323B (zh) 具有增效作用的杀虫组合物
CN108902151A (zh) 杀虫组合物在防治夜蛾和蓟马上的应用
CN101524086B (zh) 含有烯啶虫胺和乙酰甲胺磷的杀虫组合物
CN107372522A (zh) 一种含有喹螨醚的农药组合物

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 10831106

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 10831106

Country of ref document: EP

Kind code of ref document: A1