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WO2011059189A3 - Method for identifying mesenchymal stem cells by using an anti-tm4sf1 antibody and composition thereof - Google Patents

Method for identifying mesenchymal stem cells by using an anti-tm4sf1 antibody and composition thereof Download PDF

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Publication number
WO2011059189A3
WO2011059189A3 PCT/KR2010/007396 KR2010007396W WO2011059189A3 WO 2011059189 A3 WO2011059189 A3 WO 2011059189A3 KR 2010007396 W KR2010007396 W KR 2010007396W WO 2011059189 A3 WO2011059189 A3 WO 2011059189A3
Authority
WO
WIPO (PCT)
Prior art keywords
mesenchymal stem
stem cells
identifying
tm4sf1
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2010/007396
Other languages
French (fr)
Korean (ko)
Other versions
WO2011059189A2 (en
Inventor
김호언
배소현
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aprogen Inc
Original Assignee
Aprogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aprogen Inc filed Critical Aprogen Inc
Publication of WO2011059189A2 publication Critical patent/WO2011059189A2/en
Publication of WO2011059189A3 publication Critical patent/WO2011059189A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention relates to a method for identifying or separating mesenchymal stem cells by using a TM4SF1 protein specifically expressed in the mesenchymal stem cells. More specifically, the present invention provides an anti-TM4SF1 containing composition for identifying or separating mesenchymal stem cells, and a mesenchymal stem cell identifying kit and protein chip containing an anti-TM4SF1 antibody. Further, the present invention provides a method for identifying mesenchymal stem cells by using an anti-TM4SF1 antibody and a separation and purification method of the same.
PCT/KR2010/007396 2009-11-13 2010-10-27 Method for identifying mesenchymal stem cells by using an anti-tm4sf1 antibody and composition thereof Ceased WO2011059189A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020090109863A KR101168224B1 (en) 2009-11-13 2009-11-13 Method for identification of mesenchymal stem cells using anti-TM4SF1 antibody and composition for it
KR10-2009-0109863 2009-11-13

Publications (2)

Publication Number Publication Date
WO2011059189A2 WO2011059189A2 (en) 2011-05-19
WO2011059189A3 true WO2011059189A3 (en) 2011-09-29

Family

ID=43992179

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2010/007396 Ceased WO2011059189A2 (en) 2009-11-13 2010-10-27 Method for identifying mesenchymal stem cells by using an anti-tm4sf1 antibody and composition thereof

Country Status (2)

Country Link
KR (1) KR101168224B1 (en)
WO (1) WO2011059189A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180059109A1 (en) * 2016-08-31 2018-03-01 Meridigen Biotech Co., Ltd. Method of distinguishing mesenchymal stem cells and method of determining purity of mesenchymal stem cells
WO2019015696A2 (en) * 2017-07-17 2019-01-24 同济大学苏州研究院 New target for treating cancer
CN109265546B (en) * 2017-07-17 2022-05-24 同济大学苏州研究院 Novel targets for the treatment of cancer
CN109342739A (en) * 2018-11-27 2019-02-15 上海科医联创生物科技有限公司 A method of identification mescenchymal stem cell purity
KR102827384B1 (en) * 2019-08-07 2025-07-03 건국대학교 산학협력단 Composition comprising skeletal muscle stem cell-derived exosome as active ingredient for improving skin condition

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ANDREW, C. ET AL., J. CELL. BIOCHEM., vol. 89, no. 1, 2003, pages 56 - 66 *
BAE, S. ET AL., CELL TISSUE RES., vol. 335, no. 3, March 2009 (2009-03-01), pages 565 - 573 *
KIM, Y. ET AL., PFLUGERS ARCH.-EUR J PHYSIOL, vol. 455, no. 2, 2007, pages 283 - 296 *
SHIN, S. ET AL., CANCER RESEARCH, 7 April 2009 (2009-04-07) *
WAGNER, W. ET AL., EXPERIMENTAL HEMATOLOGY, vol. 33, 2005, pages 1402 - 1416 *

Also Published As

Publication number Publication date
KR20110053059A (en) 2011-05-19
KR101168224B1 (en) 2012-07-24
WO2011059189A2 (en) 2011-05-19

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