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WO2010008543A9 - Signatures moléculaires pour le diagnostic de la sclérodermie - Google Patents

Signatures moléculaires pour le diagnostic de la sclérodermie Download PDF

Info

Publication number
WO2010008543A9
WO2010008543A9 PCT/US2009/004089 US2009004089W WO2010008543A9 WO 2010008543 A9 WO2010008543 A9 WO 2010008543A9 US 2009004089 W US2009004089 W US 2009004089W WO 2010008543 A9 WO2010008543 A9 WO 2010008543A9
Authority
WO
WIPO (PCT)
Prior art keywords
molecular signatures
scleroderma
diagnosing
diagnosing scleroderma
signatures
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2009/004089
Other languages
English (en)
Other versions
WO2010008543A2 (fr
Inventor
Michael L. Whitfield
Jennifer L. Sargent
Sarah A. Pendergrass
Ausra Milano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dartmouth College
Original Assignee
Dartmouth College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dartmouth College filed Critical Dartmouth College
Priority to US13/054,244 priority Critical patent/US20110190156A1/en
Publication of WO2010008543A2 publication Critical patent/WO2010008543A2/fr
Publication of WO2010008543A9 publication Critical patent/WO2010008543A9/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PCT/US2009/004089 2008-07-15 2009-07-15 Signatures moléculaires pour le diagnostic de la sclérodermie Ceased WO2010008543A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US13/054,244 US20110190156A1 (en) 2008-07-15 2009-07-15 Molecular signatures for diagnosing scleroderma

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US8070908P 2008-07-15 2008-07-15
US61/080,709 2008-07-15
US14645209P 2009-01-22 2009-01-22
US61/146,452 2009-01-22

Publications (2)

Publication Number Publication Date
WO2010008543A2 WO2010008543A2 (fr) 2010-01-21
WO2010008543A9 true WO2010008543A9 (fr) 2010-05-27

Family

ID=41550911

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/004089 Ceased WO2010008543A2 (fr) 2008-07-15 2009-07-15 Signatures moléculaires pour le diagnostic de la sclérodermie

Country Status (2)

Country Link
US (1) US20110190156A1 (fr)
WO (1) WO2010008543A2 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ628843A (en) 2008-10-21 2016-02-26 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
US10236078B2 (en) 2008-11-17 2019-03-19 Veracyte, Inc. Methods for processing or analyzing a sample of thyroid tissue
JP6078339B2 (ja) 2009-05-07 2017-02-08 ベラサイト インコーポレイテッド 甲状腺状態の診断のための方法および組成物
EP2539712A4 (fr) * 2010-02-26 2013-09-18 Astute Medical Inc Procédés et compositions pour diagnostic et pronostic de lésion rénale et d'insuffisance rénale
EP2875356A1 (fr) * 2012-07-23 2015-05-27 INSERM - Institut National de la Santé et de la Recherche Médicale Méthode de diagnostic d'une sclérodermie
US10526655B2 (en) 2013-03-14 2020-01-07 Veracyte, Inc. Methods for evaluating COPD status
EP2971128B1 (fr) * 2013-03-15 2023-03-01 Veracyte, Inc. Biomarqueurs pour le diagnostic de maladies pulmonaires et leurs procédés d'utilisation
US11976329B2 (en) 2013-03-15 2024-05-07 Veracyte, Inc. Methods and systems for detecting usual interstitial pneumonia
US12297505B2 (en) 2014-07-14 2025-05-13 Veracyte, Inc. Algorithms for disease diagnostics
EP3770274A1 (fr) 2014-11-05 2021-01-27 Veracyte, Inc. Systèmes et procédés de diagnostic de la fibrose pulmonaire idiopathique sur des biopsies transbronchiques à l'aide de l'apprentissage automatique et de données de transcription dimensionnelle élevée
TW201720843A (zh) * 2015-11-23 2017-06-16 馬克專利公司 用於治療纖維化及／或纖維化病症之抗－αＶ整合素抗體
US20190144547A1 (en) 2015-11-23 2019-05-16 Merck Patent Gmbh Anti-alpha-v integrin antibody for the treatment of fibrosis and/or fibrotic disorders
CN110117324B (zh) * 2016-03-22 2022-08-26 苏州明人医药生物科技有限公司 一种抗肿瘤活性多肽及其用途
CN111500703B (zh) * 2020-04-26 2021-01-08 四川省人民医院 一种鉴定家族性渗出性玻璃体视网膜病变的引物、试剂、试剂盒、方法及其应用
US20230374591A1 (en) 2020-10-08 2023-11-23 The Trustees Of Dartmouth College Methods and agents for treating, preventing, diagnosing, and evaluating therapy for fibrotic, autoimmune, and inflammatory conditions
CN114700291A (zh) * 2022-04-07 2022-07-05 滁州学院 一种羽化鸡小胸品质检测方法及分级系统

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0509965D0 (en) * 2005-05-17 2005-06-22 Ml Lab Plc Improved expression elements

Also Published As

Publication number Publication date
WO2010008543A2 (fr) 2010-01-21
US20110190156A1 (en) 2011-08-04

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