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WO2009035855A3 - Novel uses of halogenated alkyl sulfonamides - Google Patents

Novel uses of halogenated alkyl sulfonamides Download PDF

Info

Publication number
WO2009035855A3
WO2009035855A3 PCT/US2008/074535 US2008074535W WO2009035855A3 WO 2009035855 A3 WO2009035855 A3 WO 2009035855A3 US 2008074535 W US2008074535 W US 2008074535W WO 2009035855 A3 WO2009035855 A3 WO 2009035855A3
Authority
WO
WIPO (PCT)
Prior art keywords
halogenated alkyl
novel uses
alkyl sulfonamides
compound
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2008/074535
Other languages
French (fr)
Other versions
WO2009035855A2 (en
Inventor
Mary W Walker
Carlos Forray
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
H Lundbeck AS
Original Assignee
H Lundbeck AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Lundbeck AS filed Critical H Lundbeck AS
Publication of WO2009035855A2 publication Critical patent/WO2009035855A2/en
Publication of WO2009035855A3 publication Critical patent/WO2009035855A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to methods of treating disorders relating to mood, anxiety, stress, sleep, cognitive impairment/dysfunction, substance dependency/abuse, metabolism, eating and chronic pain comprising administering a therapeutically effective amount of a compound of Formula I, and to uses of a compound of Formula 1 in the manufacture of a medicament for treating said disorders.
PCT/US2008/074535 2007-09-12 2008-08-28 Novel uses of halogenated alkyl sulfonamides Ceased WO2009035855A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97178707P 2007-09-12 2007-09-12
US60/971,787 2007-09-12

Publications (2)

Publication Number Publication Date
WO2009035855A2 WO2009035855A2 (en) 2009-03-19
WO2009035855A3 true WO2009035855A3 (en) 2009-04-30

Family

ID=40452775

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/074535 Ceased WO2009035855A2 (en) 2007-09-12 2008-08-28 Novel uses of halogenated alkyl sulfonamides

Country Status (1)

Country Link
WO (1) WO2009035855A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2280703A1 (en) * 2008-03-12 2011-02-09 Københavns Universitet (University Of Copenhagen) Use of npy y5 receptor antagonists for the prevention of psychostimulant and opioid abuse
CA2834429C (en) 2011-04-27 2019-07-02 Kyohei Hayashi 5-membered ring aromatic heterocyclic derivative having npy y5 receptor antagonistic activity

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998035944A1 (en) * 1997-02-14 1998-08-20 Bayer Corporation Amides as npy5 receptor antagonists
US6218408B1 (en) * 1999-06-30 2001-04-17 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (bicyclics)
US20060293341A1 (en) * 2005-06-23 2006-12-28 Vrej Jubian Alkyl sulfonamide derivatives

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998035944A1 (en) * 1997-02-14 1998-08-20 Bayer Corporation Amides as npy5 receptor antagonists
US6218408B1 (en) * 1999-06-30 2001-04-17 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (bicyclics)
US20060293341A1 (en) * 2005-06-23 2006-12-28 Vrej Jubian Alkyl sulfonamide derivatives

Also Published As

Publication number Publication date
WO2009035855A2 (en) 2009-03-19

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