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WO2009031564A1 - Ｌ－アミノ酸生産菌及びｌ－アミノ酸の製造法 - Google Patents

Ｌ－アミノ酸生産菌及びｌ－アミノ酸の製造法 Download PDF

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Publication number
WO2009031564A1
WO2009031564A1 PCT/JP2008/065833 JP2008065833W WO2009031564A1 WO 2009031564 A1 WO2009031564 A1 WO 2009031564A1 JP 2008065833 W JP2008065833 W JP 2008065833W WO 2009031564 A1 WO2009031564 A1 WO 2009031564A1
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WO
WIPO (PCT)
Prior art keywords
amino acid
producing
medium
bacterium
producing bacterium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/065833
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English (en)
French (fr)
Inventor
Yoko Asakura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Publication of WO2009031564A1 publication Critical patent/WO2009031564A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

　Ｌ－アミノ酸生産能を有し、かつ、ｙｄｃＵ、ｙｆｅＫ、ｓｍｐＡ、ｈｔｒＧ、ａｄｉＣ、ｈｔｒＡ、ｙｄｈＫ、ｂａｃＡ、ｙａｉＷ、及びｙｉｄＱから選択される１又はそれ以上の遺伝子の発現が弱まるように改変された腸内細菌科に属する細菌を培地で培養して、Ｌ－アミノ酸を該培地中に蓄積させ、該培地よりＬ－アミノ酸を採取することにより、Ｌ－アミノ酸を製造する。
PCT/JP2008/065833 2007-09-04 2008-09-03 Ｌ－アミノ酸生産菌及びｌ－アミノ酸の製造法 Ceased WO2009031564A1 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-228728 2007-09-04
JP2007228728A JP2010263789A (ja) 2007-09-04 2007-09-04 Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造法

Publications (1)

Publication Number Publication Date
WO2009031564A1 true WO2009031564A1 (ja) 2009-03-12

Family

ID=40428878

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/065833 Ceased WO2009031564A1 (ja) 2007-09-04 2008-09-03 Ｌ－アミノ酸生産菌及びｌ－アミノ酸の製造法

Country Status (2)

Country Link
JP (1) JP2010263789A (ja)
WO (1) WO2009031564A1 (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015503353A (ja) * 2012-01-06 2015-02-02 シージェイ チェイルジェダン コーポレーション Ｌ−アミノ酸を産生する微生物及びこれを用いてｌ−アミノ酸を産生する方法
WO2015060314A1 (ja) * 2013-10-21 2015-04-30 味の素株式会社 Ｌ－アミノ酸の製造法
CN112725254A (zh) * 2017-10-13 2021-04-30 四川利尔生物科技有限公司 一种l-高丝氨酸的生产菌株及其构建方法和应用
EP3904521A4 (en) * 2018-12-26 2022-03-23 Daesang Corporation E. coli variant strain or corynebacterium glutamicum variant strain producing l-amino acids, and method for producing l-amino acids using same

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602009000714D1 (de) * 2008-03-06 2011-03-24 Ajinomoto Kk L-Zystein-produzierendes Bakterium und Verfahren zur Herstellung von L-Zystein
RU2013118637A (ru) * 2013-04-23 2014-10-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА ENTEROBACTERIACEAE, В КОТОРОЙ РАЗРЕГУЛИРОВАН ГЕН yjjK

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
BABA T. ET AL.: "Construction of Eschirichia coli K-12 in-frame,single-gene knockout mutants:the Keio collection", MOLECULAR SYSTEMS BIOLOGY, 2006, pages 1 - 11, Retrieved from the Internet <URL:http://www.nature.com/msb/journal/v2/n1/pdf/msb4100050.pdf> *
DATABASE GENOBASE [online] Database accession no. ECK0160 *
DATABASE GENOBASE [online] Database accession no. ECK0373 *
DATABASE GENOBASE [online] Database accession no. ECK1436 *
DATABASE GENOBASE [online] Database accession no. ECK1641 *
DATABASE GENOBASE [online] Database accession no. ECK2414 *
DATABASE GENOBASE [online] Database accession no. ECK2613 *
DATABASE GENOBASE [online] Database accession no. ECK3045 *
DATABASE GENOBASE [online] Database accession no. ECK3047 *
DATABASE GENOBASE [online] Database accession no. ECK3680 *
IYER R. ET AL: "Arginine-agmatine antiporter in extreme acid resistance in escherichia coli", J.BACTERIOL., vol. 185, no. 22, 2003, pages 6556 - 6561 *

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015503353A (ja) * 2012-01-06 2015-02-02 シージェイ チェイルジェダン コーポレーション Ｌ−アミノ酸を産生する微生物及びこれを用いてｌ−アミノ酸を産生する方法
JP2017042167A (ja) * 2012-01-06 2017-03-02 シージェイ チェイルジェダン コーポレーション Ｌ−アミノ酸を産生する微生物及びこれを用いてｌ−アミノ酸を産生する方法
WO2015060314A1 (ja) * 2013-10-21 2015-04-30 味の素株式会社 Ｌ－アミノ酸の製造法
JPWO2015060314A1 (ja) * 2013-10-21 2017-03-09 味の素株式会社 Ｌ−アミノ酸の製造法
CN112725254A (zh) * 2017-10-13 2021-04-30 四川利尔生物科技有限公司 一种l-高丝氨酸的生产菌株及其构建方法和应用
CN112725254B (zh) * 2017-10-13 2023-07-11 湖南利尔生物科技有限公司 一种l-高丝氨酸的生产菌株及其构建方法和应用
EP3904521A4 (en) * 2018-12-26 2022-03-23 Daesang Corporation E. coli variant strain or corynebacterium glutamicum variant strain producing l-amino acids, and method for producing l-amino acids using same
EP4159866A1 (en) * 2018-12-26 2023-04-05 Daesang Corporation E. coli variant strain or corynebacterium glutamicum variant strain producing l-amino acids, and method for producing l-amino acids using same
EP4159865A1 (en) * 2018-12-26 2023-04-05 Daesang Corporation E. coli variant strain producing l-amino acids, and method for producing amino acids using same

Also Published As

Publication number Publication date
JP2010263789A (ja) 2010-11-25

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