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WO2009026116A3 - Genemap of the human genes associated with longevity - Google Patents

Genemap of the human genes associated with longevity Download PDF

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Publication number
WO2009026116A3
WO2009026116A3 PCT/US2008/073238 US2008073238W WO2009026116A3 WO 2009026116 A3 WO2009026116 A3 WO 2009026116A3 US 2008073238 W US2008073238 W US 2008073238W WO 2009026116 A3 WO2009026116 A3 WO 2009026116A3
Authority
WO
WIPO (PCT)
Prior art keywords
longevity
genemap
genes associated
human genes
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2008/073238
Other languages
French (fr)
Other versions
WO2009026116A2 (en
Inventor
Abdelmajid Belouchi
John Verner Raelson
Bruno Paquin
Quynh Nguyen-Huu
Sam Kebache
Eerdewegh Paul Van
Jonathan Segal
Randall David Little
Tim Keith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genizon Biosciences Inc
Original Assignee
Genizon Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genizon Biosciences Inc filed Critical Genizon Biosciences Inc
Publication of WO2009026116A2 publication Critical patent/WO2009026116A2/en
Publication of WO2009026116A3 publication Critical patent/WO2009026116A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention relates to the selection of a set of polymorphism markers for use in genome wide association studies based on linkage disequilibrium mapping. In particular, the invention relates to the fields of pharmacogenomics, diagnostics, patient therapy and the use of genetic haplotype information to predict an individual's susceptibility to longevity and aging related disorders and/or their response to a particular drug or drugs.
PCT/US2008/073238 2007-08-16 2008-08-15 Genemap of the human genes associated with longevity Ceased WO2009026116A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93552507P 2007-08-16 2007-08-16
US60/935,525 2007-08-16

Publications (2)

Publication Number Publication Date
WO2009026116A2 WO2009026116A2 (en) 2009-02-26
WO2009026116A3 true WO2009026116A3 (en) 2009-07-30

Family

ID=40378924

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/073238 Ceased WO2009026116A2 (en) 2007-08-16 2008-08-15 Genemap of the human genes associated with longevity

Country Status (1)

Country Link
WO (1) WO2009026116A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2488548A1 (en) * 2009-10-14 2012-08-22 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung A low density lipoprotein-related protein 1 splice variant as cancer marker
KR20120103509A (en) 2011-03-09 2012-09-19 아크레이 가부시키가이샤 Probe for detecting polymorphism in cyp3a gene, method of detecting of polymorphism, method of evaluating drug efficacy, and reagent kit for detecting polymorphism
US20190106747A1 (en) * 2016-03-21 2019-04-11 Indiana University Research And Technology Corporation Drugs, pharmacogenomics and biomarkers for acive longevity
ES2949342T3 (en) 2016-06-17 2023-09-27 Medigene Immunotherapies Gmbh T cell receptors and their uses
BR112020021903A2 (en) 2018-04-27 2021-03-02 Rocket Pharmaceuticals, Ltd. gene therapy for snc degeneration
AU2019360427A1 (en) 2018-10-19 2021-03-18 Enara Bio Limited Novel cancer antigens and methods
CN111500741A (en) * 2019-01-31 2020-08-07 田小利 Branched chain amino acid metabolism related gene SNV, determination reagent and application thereof
KR20220034039A (en) * 2019-07-05 2022-03-17 더 프란시스 크릭 인스티튜트 리미티드 Novel Cancer Antigens and Methods
EP4153614A4 (en) * 2020-05-20 2024-06-26 Spacecraft Seven, LLC MANIPULATED PARKIN AND USES THEREOF
EP4153760A4 (en) * 2020-05-21 2024-08-21 Nysnobio GT, LLC Gene therapy delivery of parkin mutants having increased activity to treat parkinson's disease
EP4304634A1 (en) * 2021-03-11 2024-01-17 Institut Curie Transmembrane neoantigenic peptides
AU2022235060A1 (en) * 2021-03-11 2023-09-28 INSERM (Institut National de la Santé et de la Recherche Médicale) Tumor neoantigenic peptides and uses thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040022781A1 (en) * 2000-12-29 2004-02-05 Spytek Kimberly A. Proteins and nucleic acids encoding same
US20060166204A1 (en) * 2002-09-26 2006-07-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Parkinson's disease susceptibility haptotype as a tool for genetic screening

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040022781A1 (en) * 2000-12-29 2004-02-05 Spytek Kimberly A. Proteins and nucleic acids encoding same
US20060166204A1 (en) * 2002-09-26 2006-07-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Parkinson's disease susceptibility haptotype as a tool for genetic screening

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
OHKUBO ET AL.: "Apolipoprotein E and Reelin ligands modulate tau phosphorylation through an Apolipoprotein E receptor/disabled-1/glycogen synthase kinase-3 Beta cascade.", FASEB JOUMAL, 18 December 2002 (2002-12-18) *

Also Published As

Publication number Publication date
WO2009026116A2 (en) 2009-02-26

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