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WO2008123901A3 - Genemap of the human genes associated with endometriosis - Google Patents

Genemap of the human genes associated with endometriosis Download PDF

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Publication number
WO2008123901A3
WO2008123901A3 PCT/US2008/001529 US2008001529W WO2008123901A3 WO 2008123901 A3 WO2008123901 A3 WO 2008123901A3 US 2008001529 W US2008001529 W US 2008001529W WO 2008123901 A3 WO2008123901 A3 WO 2008123901A3
Authority
WO
WIPO (PCT)
Prior art keywords
endometriosis
genemap
genes associated
human genes
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2008/001529
Other languages
French (fr)
Other versions
WO2008123901A2 (en
Inventor
Abdelmajid Belouchi
John Verner Raelson
Bruno Paquin
Sandy Briand
Daniel Dubois
Eerdewegh Paul Van
Jonahan Segal
Randall David Little
Tim Keith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genizon Biosciences Inc
Original Assignee
Genizon Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genizon Biosciences Inc filed Critical Genizon Biosciences Inc
Priority to EP08741999A priority Critical patent/EP2118321A4/en
Priority to CA002676415A priority patent/CA2676415A1/en
Publication of WO2008123901A2 publication Critical patent/WO2008123901A2/en
Publication of WO2008123901A3 publication Critical patent/WO2008123901A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention relates to the selection of a set of polymorphism markers for use in genome wide association studies based on linkage disequilibrium mapping. In particular, the invention relates to the fields of pharmacogenomics, diagnostics, patient therapy and the use of genetic haplotype information to predict an individual's susceptibility to ENDOMETRIOSIS disease and/or their response to a particular drug or drugs.
PCT/US2008/001529 2007-02-06 2008-02-06 Genemap of the human genes associated with endometriosis Ceased WO2008123901A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP08741999A EP2118321A4 (en) 2007-02-06 2008-02-06 Genemap of the human genes associated with endometriosis
CA002676415A CA2676415A1 (en) 2007-02-06 2008-02-06 Genemap of the human genes associated with endometriosis

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US89961507P 2007-02-06 2007-02-06
US60/899,615 2007-02-06
US94856507P 2007-07-09 2007-07-09
US60/948,565 2007-07-09

Publications (2)

Publication Number Publication Date
WO2008123901A2 WO2008123901A2 (en) 2008-10-16
WO2008123901A3 true WO2008123901A3 (en) 2009-02-19

Family

ID=39831514

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/001529 Ceased WO2008123901A2 (en) 2007-02-06 2008-02-06 Genemap of the human genes associated with endometriosis

Country Status (3)

Country Link
EP (1) EP2118321A4 (en)
CA (1) CA2676415A1 (en)
WO (1) WO2008123901A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080306034A1 (en) * 2007-06-11 2008-12-11 Juneau Biosciences, Llc Method of Administering a Therapeutic
US8932993B1 (en) 2007-06-11 2015-01-13 Juneau Biosciences, LLC. Method of testing for endometriosis and treatment therefor
WO2010124101A2 (en) * 2009-04-22 2010-10-28 Juneau Biosciences, Llc Genetic markers associated with endometriosis and use thereof
BR112013015605A2 (en) 2010-12-24 2016-10-11 Otsuka Pharma Co Ltd bioanalysis method for physiologically active substance detection
US9434991B2 (en) 2013-03-07 2016-09-06 Juneau Biosciences, LLC. Method of testing for endometriosis and treatment therefor
EP3596100A4 (en) * 2017-03-15 2021-01-13 Juneau Biosciences, L.L.C. Methods of using genetic markers associated with endometriosis

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006116867A1 (en) * 2005-04-29 2006-11-09 Genizon Biosciences Inc. Genemap of the human genes associated with crohn's disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001032920A2 (en) * 1999-11-03 2001-05-10 Metris Therapeutics Limited Agents implicated in endometriosis
US20060014166A1 (en) * 2004-01-27 2006-01-19 Yossi Cohen Novel nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of endometriosis
WO2006091254A1 (en) * 2005-02-18 2006-08-31 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Identification of molecular diagnostic markers for endometriosis in blood lymphocytes
CA2607341A1 (en) * 2005-05-05 2006-11-09 Mount Sinai Hospital Diagnosis and treatment of endometriosis

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006116867A1 (en) * 2005-04-29 2006-11-09 Genizon Biosciences Inc. Genemap of the human genes associated with crohn's disease

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BISCHOFF ET AL.: "Heritability and molecular genetic studies of endometriosis", HUMAN REPRODUCTION UPDATE, vol. 6, 2000, pages 37 - 44, XP008112249 *
HSIEH ET AL.: "T homozygote and allele of epidermal growth factor receptor 2073 gene polymorphism are associated with higher susceptibility to endometriosis and leiomyomas", FERTILITY AND STERILITY, vol. 83, 2005, pages 796 - 799, XP004776959 *
LI ET AL.: "A single nucleotide polymorphism in the E-cadherin gene promoter alters transcriptional activities", CANCER RESEARCH, vol. 60, 2000, pages 873 - 876, XP002255107 *
See also references of EP2118321A4 *

Also Published As

Publication number Publication date
EP2118321A2 (en) 2009-11-18
CA2676415A1 (en) 2008-10-16
EP2118321A4 (en) 2010-06-30
WO2008123901A2 (en) 2008-10-16

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