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WO2009024678A3 - Dispositif et procede pour la separation des composantes d'une suspension et en particulier du sang - Google Patents

Dispositif et procede pour la separation des composantes d'une suspension et en particulier du sang Download PDF

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Publication number
WO2009024678A3
WO2009024678A3 PCT/FR2008/000961 FR2008000961W WO2009024678A3 WO 2009024678 A3 WO2009024678 A3 WO 2009024678A3 FR 2008000961 W FR2008000961 W FR 2008000961W WO 2009024678 A3 WO2009024678 A3 WO 2009024678A3
Authority
WO
WIPO (PCT)
Prior art keywords
chamber
separation
duct
curved section
suspension
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FR2008/000961
Other languages
English (en)
Other versions
WO2009024678A2 (fr
Inventor
Herve Rostaing
Jean-Luc Achard
Patrick Pouteau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Centre National de la Recherche Scientifique CNRS
Commissariat a lEnergie Atomique CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Commissariat a lEnergie Atomique CEA filed Critical Centre National de la Recherche Scientifique CNRS
Publication of WO2009024678A2 publication Critical patent/WO2009024678A2/fr
Publication of WO2009024678A3 publication Critical patent/WO2009024678A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/0039—Settling tanks provided with contact surfaces, e.g. baffles, particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/0087—Settling tanks provided with means for ensuring a special flow pattern, e.g. even inflow or outflow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
    • B01D21/265—Separation of sediment aided by centrifugal force or centripetal force by using a vortex inducer or vortex guide, e.g. coil
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2221/00—Applications of separation devices
    • B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/26—Further operations combined with membrane separation processes
    • B01D2311/2676—Centrifugal separation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0418—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electro-osmotic flow [EOF]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0421—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electrophoretic flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/045—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation having annular separation channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0457—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation having three-dimensional spirally wound separation channels
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • External Artificial Organs (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Dispositif pour la séparation d'une suspension liquide (S) constituée par une phase continue liquide (PL) et au moins une phase dispersée (GB, GR), lesdites phases ayant des densités différentes, ledit dispositif comportant : un premier conduit (C1) présentant au moins une portion courbe; au moins un deuxième conduit (C2), présentant également une portion courbe, s'étendant parallèlement audit premier conduit du côté extérieur de la portion courbe de ce dernier; et au moins une cloison (CL), séparant lesdits premier et deuxième conduits et présentant à son tour une portion courbe; dans lequel ladite cloison présente une fente longitudinale (F) s'étendant le long de la portion courbe de la cloison et mettant en communication lesdits premier et deuxième conduits de manière à permettre des échanges de matière entre eux, ladite fente (F) étant située sensiblement à mi-hauteur de ladite cloison (CL). Procédé pour la séparation d'une suspension liquide (S) à l'aide d'un tel dispositif.
PCT/FR2008/000961 2007-07-18 2008-07-04 Dispositif et procede pour la separation des composantes d'une suspension et en particulier du sang Ceased WO2009024678A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0705180 2007-07-18
FR0705180A FR2918900A1 (fr) 2007-07-18 2007-07-18 Dispositif et procede pour la separation des composantes d'une suspension et en particulier du sang

Publications (2)

Publication Number Publication Date
WO2009024678A2 WO2009024678A2 (fr) 2009-02-26
WO2009024678A3 true WO2009024678A3 (fr) 2009-04-23

Family

ID=39047956

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2008/000961 Ceased WO2009024678A2 (fr) 2007-07-18 2008-07-04 Dispositif et procede pour la separation des composantes d'une suspension et en particulier du sang

Country Status (2)

Country Link
FR (1) FR2918900A1 (fr)
WO (1) WO2009024678A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2897730A4 (fr) * 2012-09-21 2016-04-27 Massachusetts Inst Technology Dispositif microfluidique et utilisations dudit dispositif
US9804068B2 (en) 2012-09-28 2017-10-31 University Of Maryland Particle separation and concentration using spiral inertial filtration
FR3007665B1 (fr) * 2013-06-28 2017-04-07 Commissariat Energie Atomique Dispositif d'extraction d'une phase liquide appauvrie en particules d'une suspension
ES2978196T3 (es) * 2015-09-03 2024-09-06 Filterart Ltd Un conducto para usar en un sistema para separar partículas suspendidas en un fluido, y un método para diseñar dicho conducto
US9968929B2 (en) * 2015-10-27 2018-05-15 Apex Biotechnology Corp. Reaction cassette and assay device
FR3048778A1 (fr) 2016-03-10 2017-09-15 Archimej Tech Dispositif d'analyse, de preference pour chimiometrie d'un echantillon sanguin.
IL251036A0 (en) 2017-03-08 2017-06-29 Aqua Hd Separation And Filtration Systems Ltd A system and a method for separation of particles suspended in a fluid
US11110374B2 (en) 2017-03-28 2021-09-07 Chromatan Inc. Continuous countercurrent spiral chromatography
CN111801200B (zh) * 2018-03-30 2022-08-23 吉列有限责任公司 包括皮肤互连构件的剃刮剃刀系统
AU2020204417B1 (en) * 2020-04-28 2021-10-28 Zhang, Shujun MR Improved apparatus and method for separating particles from a particulate suspension

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2626747A (en) * 1949-03-11 1953-01-27 Emil L Ranseen Centrifugal separator
US3327939A (en) * 1965-11-15 1967-06-27 Wladzia G P Doyle Centrifugal countercurrent exchange device with improved removable strip means
GB2024644A (en) * 1978-07-05 1980-01-16 Hitachi Ltd Centrifugal type counterflow contact apparatus
US4623470A (en) * 1981-11-09 1986-11-18 Helipump, Inc. Process and apparatus for separating or fractionating fluid mixtures
WO2001094024A1 (fr) * 2000-06-08 2001-12-13 Westfalia Separator Food Tec Gmbh Centrifugeuse avec ensemble tamis et son procede de fonctionnement
WO2002038502A1 (fr) * 2000-11-13 2002-05-16 Bayer Aktiengesellschaft Dispositif permettant d'exposer des liquides a des rayonnements
US20020196435A1 (en) * 2000-11-22 2002-12-26 Cohen David Samuel Apparatus and methods for separating agglutinants and disperse particles
WO2004113877A1 (fr) * 2003-06-13 2004-12-29 The General Hospital Corporation Systemes microfluidiques d'elimination basee sur la taille de globules rouges et de plaquettes du sang
WO2006020100A2 (fr) * 2004-07-16 2006-02-23 Smart Medical Technologies, Llc Separateur de sang en continu

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2626747A (en) * 1949-03-11 1953-01-27 Emil L Ranseen Centrifugal separator
US3327939A (en) * 1965-11-15 1967-06-27 Wladzia G P Doyle Centrifugal countercurrent exchange device with improved removable strip means
GB2024644A (en) * 1978-07-05 1980-01-16 Hitachi Ltd Centrifugal type counterflow contact apparatus
US4623470A (en) * 1981-11-09 1986-11-18 Helipump, Inc. Process and apparatus for separating or fractionating fluid mixtures
WO2001094024A1 (fr) * 2000-06-08 2001-12-13 Westfalia Separator Food Tec Gmbh Centrifugeuse avec ensemble tamis et son procede de fonctionnement
WO2002038502A1 (fr) * 2000-11-13 2002-05-16 Bayer Aktiengesellschaft Dispositif permettant d'exposer des liquides a des rayonnements
US20020196435A1 (en) * 2000-11-22 2002-12-26 Cohen David Samuel Apparatus and methods for separating agglutinants and disperse particles
WO2004113877A1 (fr) * 2003-06-13 2004-12-29 The General Hospital Corporation Systemes microfluidiques d'elimination basee sur la taille de globules rouges et de plaquettes du sang
WO2006020100A2 (fr) * 2004-07-16 2006-02-23 Smart Medical Technologies, Llc Separateur de sang en continu

Also Published As

Publication number Publication date
WO2009024678A2 (fr) 2009-02-26
FR2918900A1 (fr) 2009-01-23

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