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WO2009078036A3 - Process and intermediate of letrozole - Google Patents

Process and intermediate of letrozole Download PDF

Info

Publication number
WO2009078036A3
WO2009078036A3 PCT/IN2008/000801 IN2008000801W WO2009078036A3 WO 2009078036 A3 WO2009078036 A3 WO 2009078036A3 IN 2008000801 W IN2008000801 W IN 2008000801W WO 2009078036 A3 WO2009078036 A3 WO 2009078036A3
Authority
WO
WIPO (PCT)
Prior art keywords
letrozole
involving
formula
preparation
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IN2008/000801
Other languages
French (fr)
Other versions
WO2009078036A2 (en
Inventor
B. Vishnukant
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shilpa Medicare Ltd
Original Assignee
Shilpa Medicare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shilpa Medicare Ltd filed Critical Shilpa Medicare Ltd
Publication of WO2009078036A2 publication Critical patent/WO2009078036A2/en
Publication of WO2009078036A3 publication Critical patent/WO2009078036A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/04—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines without replacement of the other oxygen atom of the carboxyl group, e.g. imino-ethers
    • C07C257/06—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines without replacement of the other oxygen atom of the carboxyl group, e.g. imino-ethers having carbon atoms of imino-carboxyl groups bound to hydrogen atoms, to acyclic carbon atoms, or to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The present invention relates to a process for the preparation of Letrozole involving the use of novel intermediate of Formula I.
PCT/IN2008/000801 2007-12-11 2008-12-01 Process and intermediate of letrozole Ceased WO2009078036A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2971CH2007 2007-12-11
IN2971/CHE/2007 2007-12-11

Publications (2)

Publication Number Publication Date
WO2009078036A2 WO2009078036A2 (en) 2009-06-25
WO2009078036A3 true WO2009078036A3 (en) 2009-10-22

Family

ID=40795972

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2008/000801 Ceased WO2009078036A2 (en) 2007-12-11 2008-12-01 Process and intermediate of letrozole

Country Status (1)

Country Link
WO (1) WO2009078036A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2425038C2 (en) * 2009-11-27 2011-07-27 Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" (ФГУП "ГНЦ "НИОПИК") Method of producing 1-[di (4-cyanophenyl)methyl]-1,2,4-triazole
CN103664810B (en) * 2013-12-11 2016-09-14 深圳劲创生物技术有限公司 A kind of technique synthesizing letrozole

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070100149A1 (en) * 2005-11-02 2007-05-03 Palle Venkata Raghavendra A Process for preparing letrozole
US20070112202A1 (en) * 2005-11-14 2007-05-17 Chemagis Ltd. Letrozole production process
WO2007144896A1 (en) * 2006-06-13 2007-12-21 Natco Pharma Limited A method of manufacture of letrozole

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070100149A1 (en) * 2005-11-02 2007-05-03 Palle Venkata Raghavendra A Process for preparing letrozole
US20070112202A1 (en) * 2005-11-14 2007-05-17 Chemagis Ltd. Letrozole production process
WO2007144896A1 (en) * 2006-06-13 2007-12-21 Natco Pharma Limited A method of manufacture of letrozole

Also Published As

Publication number Publication date
WO2009078036A2 (en) 2009-06-25

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