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WO2009054473A1 - 反応チップ及び反応方法、遺伝子処理装置用温度調節機構及び遺伝子処理装置 - Google Patents

反応チップ及び反応方法、遺伝子処理装置用温度調節機構及び遺伝子処理装置 Download PDF

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Publication number
WO2009054473A1
WO2009054473A1 PCT/JP2008/069273 JP2008069273W WO2009054473A1 WO 2009054473 A1 WO2009054473 A1 WO 2009054473A1 JP 2008069273 W JP2008069273 W JP 2008069273W WO 2009054473 A1 WO2009054473 A1 WO 2009054473A1
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WO
WIPO (PCT)
Prior art keywords
reaction
base material
treating apparatus
face
gene treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/069273
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English (en)
French (fr)
Inventor
Sayaka Horie
Shuichi Akashi
Daisuke Numai
Ryoko Imagawa
Masaaki Chino
Eiji Kawata
Masahiko Amano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toppan Inc
Original Assignee
Toppan Printing Co Ltd
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Filing date
Publication date
Application filed by Toppan Printing Co Ltd filed Critical Toppan Printing Co Ltd
Priority to JP2009538262A priority Critical patent/JP5251882B2/ja
Publication of WO2009054473A1 publication Critical patent/WO2009054473A1/ja
Priority to US12/799,410 priority patent/US8450101B2/en
Anticipated expiration legal-status Critical
Priority to US13/573,143 priority patent/US20120322141A1/en
Priority to US13/573,138 priority patent/US20120322110A1/en
Ceased legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50851—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52—Containers specially adapted for storing or dispensing a reagent
    • B01L3/527—Containers specially adapted for storing or dispensing a reagent for a plurality of reagents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0642—Filling fluids into wells by specific techniques
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B01L2300/123—Flexible; Elastomeric
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0655—Valves, specific forms thereof with moving parts pinch valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00158—Elements containing microarrays, i.e. "biochip"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00356—Holding samples at elevated temperature (incubation)
    • G01N2035/00366—Several different temperatures used

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

【課題】反応室の表面改質等を行うことなく、簡便に気泡を残留させずに送液が可能であり、所望とする反応の正確な検出、測定を行うことが可能な反応チップを提供する。 【解決手段】本発明の反応チップは、第１の基材（樹脂基材２）の一面、第２の基材（金属基材）の一面の少なくともいずれか一方に、反応容器の一部を構成する複数の凹部６、流路の一部を構成する溝部が形成され、凹部６のうちの溝部の延在方向の少なくとも一方の縁部に、基材の一面２ｄから凹部の内壁面６ｄに向けて幅が漸次広くなり深さが漸次深くなる切り欠き部１５が形成されている。第１の基材の一面と第２の基材の一面とが互いに対向するように接合され、複数の反応容器と流路とが形成されている。
PCT/JP2008/069273 2007-10-26 2008-10-23 反応チップ及び反応方法、遺伝子処理装置用温度調節機構及び遺伝子処理装置 Ceased WO2009054473A1 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2009538262A JP5251882B2 (ja) 2007-10-26 2008-10-23 反応チップ及び反応方法、遺伝子処理装置用温度調節機構及び遺伝子処理装置
US12/799,410 US8450101B2 (en) 2007-10-26 2010-04-22 Reaction chip, reaction method, temperature controlling unit for gene treating apparatus and gene treating apparatus
US13/573,143 US20120322141A1 (en) 2007-10-26 2012-08-23 Reaction chip, reaction method, temperature controlling unit for gene treating apparatus and gene treating apparatus
US13/573,138 US20120322110A1 (en) 2007-10-26 2012-08-23 Reaction chip, reaction method, temperature controlling unit for gene treating apparatus and gene treating apparatus

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP2007279109 2007-10-26
JP2007-279107 2007-10-26
JP2007-279109 2007-10-26
JP2007279108 2007-10-26
JP2007279107 2007-10-26
JP2007-279108 2007-10-26

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US12/799,410 Continuation US8450101B2 (en) 2007-10-26 2010-04-22 Reaction chip, reaction method, temperature controlling unit for gene treating apparatus and gene treating apparatus

Publications (1)

Publication Number Publication Date
WO2009054473A1 true WO2009054473A1 (ja) 2009-04-30

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PCT/JP2008/069273 Ceased WO2009054473A1 (ja) 2007-10-26 2008-10-23 反応チップ及び反応方法、遺伝子処理装置用温度調節機構及び遺伝子処理装置

Country Status (4)

Country Link
US (3) US8450101B2 (ja)
JP (2) JP5251882B2 (ja)
TW (1) TWI510782B (ja)
WO (1) WO2009054473A1 (ja)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011064474A (ja) * 2009-09-15 2011-03-31 Toppan Printing Co Ltd 試料分析チップ、これを用いた試料分析装置及び試料分析方法
JP2011064475A (ja) * 2009-09-15 2011-03-31 Toppan Printing Co Ltd 試料分析チップ、これを用いた試料分析装置及び試料分析方法
JP2011072250A (ja) * 2009-09-30 2011-04-14 Toppan Printing Co Ltd 伝熱装置及び遺伝子処理装置
JP2011214944A (ja) * 2010-03-31 2011-10-27 Toppan Printing Co Ltd 試料分析チップ及びこれを用いた試料分析方法
WO2012153667A1 (en) * 2011-05-10 2012-11-15 Canon Kabushiki Kaisha Flow passage device and testing system using the same
WO2014119497A1 (ja) * 2013-01-31 2014-08-07 株式会社 日立ハイテクノロジーズ 生化学用カートリッジ、生化学用カートリッジ及びカートリッジホルダのセット
GB2514614A (en) * 2013-05-31 2014-12-03 Simon Johnson Chemical process apparatus and methods
WO2017043530A1 (ja) * 2015-09-08 2017-03-16 凸版印刷株式会社 生体物質検出方法
JP2017063779A (ja) * 2015-05-12 2017-04-06 積水化学工業株式会社 Ｐｃｒ用温度調節装置及び核酸増幅装置
JP2025506586A (ja) * 2023-01-31 2025-03-13 ジーンシステム カンパニー リミテッド Ｐｃｒ検査用チップ、及びそれを含むｐｃｒ検査用装置

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2009054493A1 (ja) * 2007-10-26 2011-03-10 凸版印刷株式会社 反応チップおよびその製造方法
ES2653916T3 (es) 2011-03-08 2018-02-09 Universite Laval Dispositivo centrípeto fluídico
DE102014200467A1 (de) * 2014-01-14 2015-07-16 Robert Bosch Gmbh Mikrofluidisches System sowie Verfahren zum Analysieren einer Probe biologischen Materials
JP6665548B2 (ja) * 2015-03-06 2020-03-13 ソニー株式会社 マイクロチップ、並びに分析装置及び分析方法
USD799715S1 (en) 2015-10-23 2017-10-10 Gene POC, Inc. Fluidic centripetal device
WO2017131951A1 (en) * 2016-01-28 2017-08-03 Becton, Dickinson And Company Enhanced composite liquid cell (clc) devices, and methods for using the same
US11491489B2 (en) 2017-12-28 2022-11-08 Stmicroelectronics S.R.L. Microfluidic connector group, microfluidic device and manufacturing process thereof, in particular for a cartridge for sample preparation and molecule analysis
WO2019130558A1 (ja) * 2017-12-28 2019-07-04 株式会社ニコン 流体デバイスおよび流路供給システム
US11511278B2 (en) 2017-12-28 2022-11-29 Stmicroelectronics S.R.L. Solid reagent containment unit, in particular for a portable microfluidic device for sample preparation and molecule analysis
US11717825B2 (en) 2017-12-28 2023-08-08 Stmicroelectronics S.R.L. Magnetically controllable valve and portable microfluidic device having a magnetically controllable valve, in particular cartridge for sample preparation and molecule analysis
US11278897B2 (en) 2017-12-28 2022-03-22 Stmicroelectronics S.R.L. Cartridge for sample preparation and molecule analysis, cartridge control machine, sample preparation system and method using the cartridge
US11110457B2 (en) 2017-12-28 2021-09-07 Stmicroelectronics S.R.L. Analysis unit for a transportable microfluidic device, in particular for sample preparation and molecule analysis
DE102018222847A1 (de) * 2018-12-21 2020-07-09 Robert Bosch Gmbh Verfahren zum Vorlagern wenigstens eines Reagenzes in einem mikrofluidischen System und mikrofluidisches System
EP4209574A4 (en) * 2020-09-02 2024-04-17 Hitachi High-Tech Corporation Temperature control device
CN115735005B (zh) * 2021-04-29 2025-07-08 京东方科技集团股份有限公司 芯片装载结构、分析装置及分析系统
CN117511739B (zh) * 2024-01-04 2024-03-12 中日友好医院(中日友好临床医学研究所) 微流体骨类器官芯片的构建方法及装置
WO2025231004A1 (en) * 2024-04-30 2025-11-06 Gen-Probe Incorporated Fluidic cartridge and apparatuses for processing fluidic cartridges

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002505946A (ja) * 1998-03-11 2002-02-26 マイクロパーツ ゲゼルシャフト フィー ミクロシュトルクチューテクニク エムベーハー 試料担体
JP2004502164A (ja) * 2000-06-28 2004-01-22 スリーエム　イノベイティブ　プロパティズ　カンパニー サンプル処理装置
JP3532826B2 (ja) * 1990-02-16 2004-05-31 エフ．ホフマン−ラ ロシュ アーゲー ポリメラーゼ連鎖反応の特異性と簡便性の改良
WO2006069757A1 (de) * 2004-12-23 2006-07-06 Perdita Backes Neuartige mikrofluidische probenträger
JP2006238848A (ja) * 2005-03-07 2006-09-14 Yamaha Corp 遺伝子検査用温度調節装置
JP2006254838A (ja) * 2005-03-18 2006-09-28 Toppan Printing Co Ltd 検出チップ及びこれを用いた物質の検出方法
JP2006275723A (ja) * 2005-03-29 2006-10-12 Yamaha Corp マイクロチップ用温度制御装置の製造方法
JP2007090290A (ja) * 2005-09-30 2007-04-12 Toppan Printing Co Ltd 反応チップおよび反応方法

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4756884A (en) * 1985-08-05 1988-07-12 Biotrack, Inc. Capillary flow device
JPH03297377A (ja) * 1990-04-12 1991-12-27 Seiko Instr Inc 自動反応装置
US5609828A (en) 1995-05-31 1997-03-11 bio M erieux Vitek, Inc. Sample card
JP4248610B2 (ja) 1996-03-21 2009-04-02 技術研究組合医療福祉機器研究所 液体回路
WO1997036681A1 (en) * 1996-04-03 1997-10-09 The Perkin-Elmer Corporation Device and method for multiple analyte detection
JP3661112B2 (ja) 1996-05-27 2005-06-15 独立行政法人理化学研究所 微量検体のためのインキュベーターの温度制御方法及びインキュベーター
JP3686917B2 (ja) 1996-06-05 2005-08-24 独立行政法人理化学研究所 微量検体のためのインキュベーター
AU734957B2 (en) 1997-05-16 2001-06-28 Alberta Research Council Inc. Microfluidic system and methods of use
JP2002300894A (ja) 2001-02-01 2002-10-15 Inst Of Physical & Chemical Res 一塩基多型タイピング方法
JP2002350378A (ja) * 2001-05-23 2002-12-04 Fujitsu Ltd 熱制御プレート
WO2003004596A1 (en) * 2001-07-06 2003-01-16 Precision System Science Co., Ltd. Reaction container and reaction device
US20040209331A1 (en) * 2001-07-16 2004-10-21 Kirk Ririe Thermal cycling system and method of use
JP3696141B2 (ja) * 2001-09-27 2005-09-14 株式会社東芝 化学分析装置、分析方法
JP4155749B2 (ja) * 2002-03-20 2008-09-24 日本碍子株式会社 ハニカム構造体の熱伝導率の測定方法
JP2004061320A (ja) * 2002-07-29 2004-02-26 Kawamura Inst Of Chem Res マイクロ流体デバイスの送液方法
DE10313201A1 (de) * 2003-03-21 2004-10-07 Steag Microparts Gmbh Mikrostrukturierte Trennvorrichtung und mikrofluidisches Verfahren zum Abtrennen von flüssigen Bestandteilen aus einer Flüssigkeit, die Partikel enthält
JP4208820B2 (ja) * 2003-11-28 2009-01-14 株式会社東芝 核酸検出カセット
US20080213755A1 (en) * 2004-01-12 2008-09-04 Applera Corporation Method and Device for Detection of Nucleic Acid Sequences
US20050249641A1 (en) * 2004-04-08 2005-11-10 Boehringer Ingelheim Microparts Gmbh Microstructured platform and method for manipulating a liquid
JP2006078414A (ja) * 2004-09-13 2006-03-23 Alps Electric Co Ltd 検査用プレート
JP2006112881A (ja) * 2004-10-14 2006-04-27 Nikkiso Co Ltd 生体物質測定装置および生体物質測定装置用チップ
US20070003443A1 (en) * 2005-06-23 2007-01-04 Applera Corporation Thermal-cycling pipette tip
JP2007021351A (ja) * 2005-07-15 2007-02-01 Yokogawa Electric Corp 化学反応用カートリッジおよび化学反応処理システム
JP2007136292A (ja) * 2005-11-15 2007-06-07 National Institute Of Advanced Industrial & Technology マイクロチャネル構造体の製造方法、マイクロチャネル構造体、およびマイクロリアクタ
JP4857800B2 (ja) * 2005-12-27 2012-01-18 凸版印刷株式会社 温度制御方法
JP4751719B2 (ja) * 2005-12-28 2011-08-17 株式会社島津製作所 遺伝子解析装置
JP4870991B2 (ja) * 2006-01-20 2012-02-08 凸版印刷株式会社 反応容器
JPWO2009054493A1 (ja) * 2007-10-26 2011-03-10 凸版印刷株式会社 反応チップおよびその製造方法

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3532826B2 (ja) * 1990-02-16 2004-05-31 エフ．ホフマン−ラ ロシュ アーゲー ポリメラーゼ連鎖反応の特異性と簡便性の改良
JP2002505946A (ja) * 1998-03-11 2002-02-26 マイクロパーツ ゲゼルシャフト フィー ミクロシュトルクチューテクニク エムベーハー 試料担体
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