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WO2008123128A1 - アディポネクチン産生促進剤 - Google Patents

アディポネクチン産生促進剤 Download PDF

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Publication number
WO2008123128A1
WO2008123128A1 PCT/JP2008/055238 JP2008055238W WO2008123128A1 WO 2008123128 A1 WO2008123128 A1 WO 2008123128A1 JP 2008055238 W JP2008055238 W JP 2008055238W WO 2008123128 A1 WO2008123128 A1 WO 2008123128A1
Authority
WO
WIPO (PCT)
Prior art keywords
enhancer
beverage
food
adiponectin production
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/055238
Other languages
English (en)
French (fr)
Inventor
Norihisa Kato
Kazunobu Tokunaga
Kazuhisa Tsujimoto
Hideyuki Yamada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seiren Co Ltd
Original Assignee
Seiren Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seiren Co Ltd filed Critical Seiren Co Ltd
Priority to US12/450,286 priority Critical patent/US8722614B2/en
Priority to EP08722602A priority patent/EP2127663A4/en
Publication of WO2008123128A1 publication Critical patent/WO2008123128A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1767Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52Adding ingredients
    • A23L2/66Proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/18Peptides; Protein hydrolysates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/01Hydrolysed proteins; Derivatives thereof
    • A61K38/012Hydrolysed proteins; Derivatives thereof from animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

 本発明は、セリシンを有効成分として含んでなるアディポネクチン産生促進剤、およびそれを含む医薬および飲食品に関する。これらは、肥満に伴う動脈硬化、脂肪肝、糖尿病などのような、血中のアディポネクチン濃度の低下に起因する各種疾病の予防または改善に有効である。本発明よる促進剤、医薬組成物、および飲食品は、アディポネクチンの産生促進効果に優れ、かつ安全性が高く、各種の医薬や飲食品に幅広く応用が期待できる。
PCT/JP2008/055238 2007-03-23 2008-03-21 アディポネクチン産生促進剤 Ceased WO2008123128A1 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US12/450,286 US8722614B2 (en) 2007-03-23 2008-03-21 Adiponectin production enhancer
EP08722602A EP2127663A4 (en) 2007-03-23 2008-03-21 ADIPONECTIN PRODUCTION PROMOTER

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007077131A JP2010018522A (ja) 2007-03-23 2007-03-23 アディポネクチン産生促進剤
JP2007-077131 2007-03-23

Publications (1)

Publication Number Publication Date
WO2008123128A1 true WO2008123128A1 (ja) 2008-10-16

Family

ID=39830625

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/055238 Ceased WO2008123128A1 (ja) 2007-03-23 2008-03-21 アディポネクチン産生促進剤

Country Status (4)

Country Link
US (1) US8722614B2 (ja)
EP (1) EP2127663A4 (ja)
JP (1) JP2010018522A (ja)
WO (1) WO2008123128A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010180149A (ja) * 2009-02-04 2010-08-19 Lintec Corp 嚥下補助剤

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101213825B1 (ko) 2010-07-16 2012-12-18 서울대학교산학협력단 세린을 유효성분으로 함유하는 지방간 질환의 예방 및 치료용 조성물
EP2676670A4 (en) * 2011-02-14 2014-08-27 Amino Up Chemical Co Ltd PROMOTER FOR PRODUCING ADIPONECTIN, AND MEDICINAL COMPOSITION, FOOD, BEVERAGE AND FEED CONTAINING AN ADIPONECTIN PRODUCTION PROMOTER
US9138455B2 (en) * 2013-03-15 2015-09-22 Mead Johnson Nutrition Company Activating adiponectin by casein hydrolysate
US9668999B2 (en) * 2014-04-23 2017-06-06 Semi Labs Limited Method for the treatment of hypercholesterolemia
KR20200083247A (ko) * 2018-12-31 2020-07-08 (주) 엔아이앤팜 세리신을 포함하는 지방간 치료, 예방, 또는 완화용 조성물 및 상기 조성물의 제조 방법
JP2022519330A (ja) * 2018-12-31 2022-03-22 株式会社エヌアイアンドパーム セリシンを含む脂肪肝の治療、予防、又は緩和用組成物及び該組成物の製造方法
JP2021029143A (ja) * 2019-08-20 2021-03-01 オリザ油化株式会社 糖化抑制剤

Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01256351A (ja) * 1988-04-01 1989-10-12 Terumo Corp 絹蛋白質を用いた食品およびその製造方法
JPH10140154A (ja) * 1996-11-08 1998-05-26 Seiren Co Ltd 抗酸化剤
JPH10265403A (ja) * 1997-03-24 1998-10-06 Seiren Co Ltd チロシナーゼ活性阻害剤
JP2000184868A (ja) * 1998-12-21 2000-07-04 Seiren Co Ltd 飲食品用水
JP2000256210A (ja) 1999-03-04 2000-09-19 Seiren Co Ltd 大腸ガン予防剤
JP2000312568A (ja) 1999-03-04 2000-11-14 Seiren Co Ltd 難消化性飲食品添加物及び健康補助剤
JP2001354584A (ja) * 2000-06-14 2001-12-25 Aioi Hakko:Kk 皮膚癌予防剤
JP2002128691A (ja) 2000-10-24 2002-05-09 National Institute Of Agrobiological Sciences セリシン含有素材、その製造方法およびその使用方法
JP2003231610A (ja) * 2002-02-05 2003-08-19 Mikimoto Pharmaceut Co Ltd 乳化組成物
JP2004018648A (ja) * 2002-06-14 2004-01-22 Seiren Co Ltd 抗酸化剤
JP2004244371A (ja) * 2003-02-14 2004-09-02 Kenji Nakamura 保湿組成物及びその製造方法
JP2006056836A (ja) 2004-08-20 2006-03-02 Taiyo Kagaku Co Ltd 脂肪組織特異分泌蛋白産生増強組成物
JP2006232787A (ja) * 2005-02-28 2006-09-07 Seiren Co Ltd 水溶性シルクタンパク質を含有する含水組成物
JP2007031302A (ja) 2005-07-25 2007-02-08 Noevir Co Ltd アディポネクチン産生促進剤、及び代謝異常症候群予防剤
JP2007077131A (ja) 2005-09-15 2007-03-29 Shigeharu Kaiho にがりを使用した歯磨き液の製造法

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* Cited by examiner, † Cited by third party
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KR100478928B1 (ko) 1996-11-08 2005-08-18 세이렌가부시끼가이샤 세리신또는세리신가수분해물을유효성분으로하는비의약용항산화제,화장품,식품변색방지제,음식물,심근경색치료제,동맥경화치료제,당뇨병치료제,암치료제,또는뇌줄중치료제
WO2000051627A1 (fr) * 1999-03-04 2000-09-08 Seiren Co., Ltd. Preparations orales fonctionnelles
GB0213612D0 (en) * 2002-06-13 2002-07-24 Novartis Nutrition Ag Organic compounds
US20060128797A1 (en) * 2004-12-15 2006-06-15 Yanming Wang Method and composition for resuscitation

Patent Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01256351A (ja) * 1988-04-01 1989-10-12 Terumo Corp 絹蛋白質を用いた食品およびその製造方法
JPH10140154A (ja) * 1996-11-08 1998-05-26 Seiren Co Ltd 抗酸化剤
JPH10265403A (ja) * 1997-03-24 1998-10-06 Seiren Co Ltd チロシナーゼ活性阻害剤
JP2000184868A (ja) * 1998-12-21 2000-07-04 Seiren Co Ltd 飲食品用水
JP2000256210A (ja) 1999-03-04 2000-09-19 Seiren Co Ltd 大腸ガン予防剤
JP2000312568A (ja) 1999-03-04 2000-11-14 Seiren Co Ltd 難消化性飲食品添加物及び健康補助剤
JP2001354584A (ja) * 2000-06-14 2001-12-25 Aioi Hakko:Kk 皮膚癌予防剤
JP2002128691A (ja) 2000-10-24 2002-05-09 National Institute Of Agrobiological Sciences セリシン含有素材、その製造方法およびその使用方法
JP2003231610A (ja) * 2002-02-05 2003-08-19 Mikimoto Pharmaceut Co Ltd 乳化組成物
JP2004018648A (ja) * 2002-06-14 2004-01-22 Seiren Co Ltd 抗酸化剤
JP2004244371A (ja) * 2003-02-14 2004-09-02 Kenji Nakamura 保湿組成物及びその製造方法
JP2006056836A (ja) 2004-08-20 2006-03-02 Taiyo Kagaku Co Ltd 脂肪組織特異分泌蛋白産生増強組成物
JP2006232787A (ja) * 2005-02-28 2006-09-07 Seiren Co Ltd 水溶性シルクタンパク質を含有する含水組成物
JP2007031302A (ja) 2005-07-25 2007-02-08 Noevir Co Ltd アディポネクチン産生促進剤、及び代謝異常症候群予防剤
JP2007077131A (ja) 2005-09-15 2007-03-29 Shigeharu Kaiho にがりを使用した歯磨き液の製造法

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See also references of EP2127663A4
TADOKOR T. ET AL.: "Shokuhin Miriyo Shigen to Shiteno Silk no Oyo o Mezasu - Silk Tanpakushitsu no Shokuhin Kinosei o Akiraka ni suru Eiyogakuteki Kenkyu -", YASAN, vol. 55, January 2006 (2006-01-01), pages 11 - 14, XP003021991 *
ZHAORIGETU S. ET AL.: "Silk protein, sericin, suppresses DMBA-TPA-induced mouse skin tumorigenesis by reducing oxidative stress, inflammatory responses and endogenous tumor promoter TNF-alpha", ONCOLOGY REPORTS, vol. 10, no. 3, 2003, pages 537 - 543, XP008113880 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010180149A (ja) * 2009-02-04 2010-08-19 Lintec Corp 嚥下補助剤

Also Published As

Publication number Publication date
US8722614B2 (en) 2014-05-13
US20100035810A1 (en) 2010-02-11
EP2127663A1 (en) 2009-12-02
JP2010018522A (ja) 2010-01-28
EP2127663A4 (en) 2011-04-13

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